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PRJEB1986: zebrafish developmental stages transcriptome

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Results for zbtb14

Z-value: 3.09

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Transcription factors associated with zbtb14

Gene Symbol Gene ID Gene Info
ENSDARG00000098273 zinc finger and BTB domain containing 14

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
zbtb14dr11_v1_chr24_+_41989108_41989108-0.282.5e-01Click!

Activity profile of zbtb14 motif

Sorted Z-values of zbtb14 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_22281854 19.85 ENSDART00000146319
crystallin, gamma M2d3
chr14_+_46313135 12.69 ENSDART00000172902
crystallin, beta A1, like 1
chr25_+_14165447 10.30 ENSDART00000145387
SH3 and multiple ankyrin repeat domains 2
chr18_-_5692292 8.98 ENSDART00000121503
complexin 3b
chr23_+_45611649 8.74 ENSDART00000169521
doublecortin-like kinase 2b
chr4_-_797831 8.55 ENSDART00000158970
ENSDART00000170012
microtubule-associated protein, RP/EB family, member 3b
chr2_-_22688651 8.29 ENSDART00000013863
alanine-glyoxylate aminotransferase b
chr2_+_42724404 8.09 ENSDART00000075392
brain abundant, membrane attached signal protein 1
chr1_+_53321878 7.87 ENSDART00000143909
TBC1 domain family, member 9 (with GRAM domain)
chr7_+_73332486 7.84 ENSDART00000174119
ENSDART00000092051
ENSDART00000192388

chr21_+_11468642 7.44 ENSDART00000041869
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr16_-_43026273 7.28 ENSDART00000156820
ENSDART00000189080
si:dkey-7j14.5
chr23_-_44226556 7.09 ENSDART00000149115
zgc:158659
chr14_+_46313396 7.03 ENSDART00000047525
crystallin, beta A1, like 1
chr7_+_67451108 6.82 ENSDART00000163840
glycine cleavage system protein H (aminomethyl carrier), b
chr7_+_39624728 6.72 ENSDART00000173847
ENSDART00000173845
protein tyrosine phosphatase, non-receptor type 5
chr15_-_43164591 6.56 ENSDART00000171305
adaptor-related protein complex 1, sigma 3 subunit, a
chr21_+_11468934 5.86 ENSDART00000126045
ENSDART00000129744
ENSDART00000102368
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr3_-_21280373 5.85 ENSDART00000003939
synaptogyrin 1a
chr21_+_6212844 5.82 ENSDART00000150301
formin binding protein 1b
chr5_-_22952156 5.73 ENSDART00000111146
si:ch211-26b3.4
chr13_+_27073901 5.63 ENSDART00000146227
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr18_-_44527124 5.54 ENSDART00000189471
amyloid beta (A4) precursor-like protein 2
chr3_-_62087346 5.54 ENSDART00000092665
sterol regulatory element binding transcription factor 1
chr3_+_17744339 5.50 ENSDART00000132622
zinc finger protein 385C
chr13_+_30054996 5.34 ENSDART00000110061
ENSDART00000186045
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr20_-_3953631 5.32 ENSDART00000124197

chr18_-_6856380 5.21 ENSDART00000175747
protein phosphatase 6, regulatory subunit 2b
chr5_+_63668735 5.13 ENSDART00000134261
ENSDART00000097330
dynamin 1b
chr1_-_21409877 5.11 ENSDART00000102782
glutamate receptor, ionotropic, AMPA 2a
chr23_-_306796 5.00 ENSDART00000143125
ankyrin repeat and sterile alpha motif domain containing 1Aa
chr5_-_69180587 4.93 ENSDART00000156681
ENSDART00000160753
zgc:171967
chr11_+_7324704 4.85 ENSDART00000031937
DIRAS family, GTP-binding RAS-like 1a
chr14_-_7306983 4.84 ENSDART00000158914
si:ch211-51f19.1
chr16_-_43025885 4.84 ENSDART00000193146
ENSDART00000157302
si:dkey-7j14.5
chr13_-_27767330 4.68 ENSDART00000131631
ENSDART00000112553
ENSDART00000189911
regulating synaptic membrane exocytosis 1a
chr17_-_3986236 4.67 ENSDART00000188794
ENSDART00000160830
si:ch1073-140o9.2
chr3_-_36115339 4.60 ENSDART00000187406
ENSDART00000123505
ENSDART00000151775
RAB11 family interacting protein 4 (class II) a
chr13_+_30055171 4.52 ENSDART00000143581
ENSDART00000132027
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr7_+_74141297 4.50 ENSDART00000164992
RNA binding protein with multiple splicing
chr9_-_52814204 4.50 ENSDART00000140771
ENSDART00000007401
si:ch211-45c16.2
chr11_-_37589293 4.44 ENSDART00000172989
bassoon (presynaptic cytomatrix protein) b
chr1_-_50859053 4.43 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
chr8_-_29719393 4.39 ENSDART00000077635
si:ch211-103n10.5
chr16_-_26074529 4.37 ENSDART00000148653
ENSDART00000148923
transmembrane protein 145
chr1_-_56223913 4.35 ENSDART00000019573
zgc:65894
chr14_-_2163454 4.32 ENSDART00000160123
ENSDART00000169653
protocadherin 2 alpha b 9
protocadherin 2 alpha c
chr7_+_4162994 4.30 ENSDART00000172800
si:ch211-63p21.1
chr18_+_42970208 4.29 ENSDART00000084454
nectin cell adhesion molecule 1b
chr12_+_6214041 4.28 ENSDART00000179759
protein kinase, cGMP-dependent, type Ib
chr14_-_48588422 4.28 ENSDART00000161147
si:ch211-154c21.1
chr5_+_28973264 4.25 ENSDART00000005638
syntaxin binding protein 1b
chr24_+_5840258 4.24 ENSDART00000087034
transient receptor potential cation channel, subfamily C, member 1
chr4_-_18434924 4.22 ENSDART00000190271
suppressor of cytokine signaling 2
chr10_+_466926 4.21 ENSDART00000145220
ARVCF, delta catenin family member a
chr5_-_69180227 4.20 ENSDART00000154816
zgc:171967
chr2_-_57110477 4.13 ENSDART00000181132
solute carrier family 25, member 42
chr8_-_410728 4.12 ENSDART00000151255
tripartite motif containing 36
chr10_-_33156789 4.11 ENSDART00000192268
ENSDART00000182065
ENSDART00000081170
cut-like homeobox 1a
chr5_+_28972935 4.08 ENSDART00000193274
syntaxin binding protein 1b
chr20_+_50852356 4.07 ENSDART00000167517
ENSDART00000168396
gephyrin b
chr25_-_22639133 4.07 ENSDART00000073583
immunoglobulin superfamily containing leucine-rich repeat 2
chr9_+_53707240 4.01 ENSDART00000171490
si:ch211-199f5.1
chr20_-_54869006 3.98 ENSDART00000184817

chr1_-_53700392 3.96 ENSDART00000127216
family with sequence similarity 161, member A
chr19_-_5254699 3.95 ENSDART00000081951
syntaxin 1B
chr19_-_25301711 3.93 ENSDART00000175739
regulating synaptic membrane exocytosis 3
chr20_-_44557037 3.79 ENSDART00000140995
major facilitator superfamily domain containing 2B
chr4_-_5764255 3.78 ENSDART00000113864
failed axon connections homolog a
chr20_-_40451115 3.71 ENSDART00000075092
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr16_+_45456066 3.71 ENSDART00000093365
synaptic Ras GTPase activating protein 1b
chr1_+_20635190 3.70 ENSDART00000145418
ENSDART00000148518
ENSDART00000139461
ENSDART00000102969
ENSDART00000166479
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr1_-_20911297 3.70 ENSDART00000078271
carboxypeptidase E
chr25_+_37209619 3.64 ENSDART00000112192
si:dkey-234i14.3
chr20_-_53624645 3.57 ENSDART00000083427
ENSDART00000152920
solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29
chr23_+_26039524 3.55 ENSDART00000142851
inter-alpha-trypsin inhibitor heavy chain family, member 6
chr12_+_12112384 3.54 ENSDART00000152431
glutamate receptor, ionotropic, delta 1b
chr3_-_36944749 3.53 ENSDART00000154501
contactin associated protein 1
chr24_+_5840748 3.50 ENSDART00000139191
transient receptor potential cation channel, subfamily C, member 1
chr13_-_29421331 3.49 ENSDART00000150228
choline O-acetyltransferase a
chr2_-_57227542 3.43 ENSDART00000182675
ENSDART00000159480
BTB (POZ) domain containing 2b
chr12_-_36045283 3.43 ENSDART00000160646
G protein-coupled receptor, class C, group 5, member C
chr11_-_34188346 3.41 ENSDART00000172978
ATPase 13A3
chr14_-_6931889 3.37 ENSDART00000166439
si:ch211-266k2.1
chr20_-_8419057 3.37 ENSDART00000145841
Dab, reelin signal transducer, homolog 1a (Drosophila)
chr11_+_575665 3.37 ENSDART00000122133
MKRN2 opposite strand, tandem duplicate 1
chr25_+_6122823 3.34 ENSDART00000191824
ENSDART00000067514
RNA binding protein with multiple splicing 2a
chr5_-_34185497 3.31 ENSDART00000146321
fibrinogen C domain containing 1
chr8_-_5220125 3.31 ENSDART00000035676
BCL2 interacting protein 3 like a
chr23_+_44732863 3.31 ENSDART00000160044
ENSDART00000172268
ATPase Na+/K+ transporting subunit beta 2a
chr7_-_47850702 3.22 ENSDART00000109511
si:ch211-186j3.6
chr17_-_52594756 3.20 ENSDART00000167288
si:ch211-173a9.7
chr13_-_31829786 3.19 ENSDART00000138667
SERTA domain containing 4
chr11_-_33960318 3.19 ENSDART00000087597
collagen, type VI, alpha 2
chr17_+_2162916 3.18 ENSDART00000103775
p21 protein (Cdc42/Rac)-activated kinase 6a
chr19_-_13733870 3.16 ENSDART00000177773
erythrocyte membrane protein band 4.1a
chr24_-_6501211 3.15 ENSDART00000186241
ENSDART00000109040
ENSDART00000136154
G protein-coupled receptor 158a
chr23_+_45611980 3.12 ENSDART00000181582
doublecortin-like kinase 2b
chr19_-_3574060 3.12 ENSDART00000105120
transmembrane protein 170B
chr23_+_45845423 3.12 ENSDART00000183404
lamin L3
chr18_-_6855991 3.12 ENSDART00000135206
protein phosphatase 6, regulatory subunit 2b
chr3_+_3810919 3.08 ENSDART00000056035

chr12_-_43576437 3.05 ENSDART00000182226
ENSDART00000191641
protein tyrosine phosphatase, receptor type, E, a
chr22_-_21150845 3.04 ENSDART00000027345
transmembrane protein 59-like
chr24_-_28245872 3.04 ENSDART00000167861
cytochrome c oxidase subunit IV isoform 1, like
chr22_-_12160283 3.03 ENSDART00000146785
ENSDART00000128176
transmembrane protein 163b
chr5_-_21030934 3.02 ENSDART00000133461
ENSDART00000098667
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1
chr24_+_35881124 3.00 ENSDART00000143015
kelch-like family member 14
chr16_+_49601838 3.00 ENSDART00000168570
ENSDART00000159236
si:dkey-82o10.4
chr8_+_23916647 2.98 ENSDART00000143152
copine Va
chr17_+_3993772 2.95 ENSDART00000170822
ENSDART00000168613
ENSDART00000186174
thioredoxin-related transmembrane protein 4
chr17_-_26537928 2.94 ENSDART00000155692
ENSDART00000122366
coiled-coil serine-rich protein 2a
chr17_-_20287530 2.94 ENSDART00000078703
ENSDART00000191289
adducin 3 (gamma) b
chr9_-_849069 2.89 ENSDART00000136091
complement component 1, q subcomponent-like 2
chr8_+_48603398 2.89 ENSDART00000074900
zgc:195023
chr14_-_2400668 2.85 ENSDART00000172717
ENSDART00000182882
si:ch73-233f7.1
chr14_-_4682114 2.83 ENSDART00000014454
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4
chr1_+_9004719 2.83 ENSDART00000006211
ENSDART00000137211
protein kinase C, beta a
chr11_-_575786 2.83 ENSDART00000019997
makorin, ring finger protein, 2
chr7_+_32722227 2.82 ENSDART00000126565
si:ch211-150g13.3
chr14_-_9199968 2.82 ENSDART00000146113
Cdc42 guanine nucleotide exchange factor (GEF) 9b
chr1_-_22370660 2.81 ENSDART00000127506
si:ch73-380n15.2
chr10_-_15405564 2.80 ENSDART00000020665
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr12_+_49006048 2.80 ENSDART00000184102
carbohydrate (chondroitin 6) sulfotransferase 3b
chr7_-_49594995 2.78 ENSDART00000174161
ENSDART00000109147
BR serine/threonine kinase 2b
chr16_-_42152145 2.78 ENSDART00000038748
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr11_-_10828539 2.76 ENSDART00000040180
T-box, brain, 1a
chr4_-_9810999 2.74 ENSDART00000146858
si:dkeyp-27e10.3
chr2_+_49417900 2.72 ENSDART00000122742
ENSDART00000160783
RAR-related orphan receptor C b
chr22_-_80533 2.70 ENSDART00000183124

chr23_+_45906137 2.68 ENSDART00000159939
ATP-binding cassette, sub-family G (WHITE), member 2a
chr2_+_394166 2.68 ENSDART00000155733
myosin light chain kinase family, member 4a
chr13_+_31757331 2.67 ENSDART00000044282
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) a
chr16_-_13388821 2.67 ENSDART00000144062
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b
chr7_+_14632157 2.64 ENSDART00000161264
neurotrophic tyrosine kinase, receptor, type 3b
chr22_-_372723 2.63 ENSDART00000112895
si:zfos-1324h11.5
chr14_-_1454045 2.62 ENSDART00000161460
phosphoethanolamine methyltransferase
chr20_-_1151265 2.61 ENSDART00000012376
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr12_+_21299338 2.57 ENSDART00000074540
ENSDART00000133188
carbonic anhydrase Xa
chr17_+_51764310 2.55 ENSDART00000157171
si:ch211-168d23.3
chr7_-_52334429 2.55 ENSDART00000187372

chr10_+_16756546 2.55 ENSDART00000168624

chr23_+_4583747 2.54 ENSDART00000160350

chr5_-_31712399 2.54 ENSDART00000141328
phosphatidylinositol-4-phosphate 5-kinase-like 1
chr16_+_3004422 2.53 ENSDART00000189969

chr2_-_30324610 2.52 ENSDART00000185422
junctophilin 1b
chr12_+_1000323 2.51 ENSDART00000054363
si:ch1073-272o11.3
chr25_+_3677650 2.51 ENSDART00000154348
prion protein, related sequence 3
chr11_+_27133560 2.51 ENSDART00000158411
histone deacetylase 11
chr19_+_41075488 2.48 ENSDART00000138687
protein phosphatase 1, regulatory subunit 9A
chr10_-_21054059 2.44 ENSDART00000139733
protocadherin 1a
chr24_-_35699595 2.43 ENSDART00000167990
microtubule-associated protein, RP/EB family, member 2
chr18_-_44526940 2.42 ENSDART00000077125
amyloid beta (A4) precursor-like protein 2
chr24_-_25673405 2.41 ENSDART00000186081
ENSDART00000110241
ENSDART00000142351
connector enhancer of kinase suppressor of Ras 2a
chr23_-_32129569 2.40 ENSDART00000167761
ENSDART00000139569
zgc:92658
chr10_+_15064433 2.36 ENSDART00000179978
prostate androgen-regulated mucin-like protein 1
chr14_-_2209742 2.35 ENSDART00000054889
protocadherin 2 alpha b 5
chr14_-_34276574 2.31 ENSDART00000021437
glutamate receptor, ionotropic, AMPA 1a
chr11_+_41858807 2.30 ENSDART00000161605
intermediate filament family orphan 2b
chr2_-_54946834 2.29 ENSDART00000192280

chr4_-_2196798 2.28 ENSDART00000110178
ENSDART00000149330
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr18_+_19974289 2.25 ENSDART00000090334
ENSDART00000192982
SKI family transcriptional corepressor 1b
chr25_-_4733221 2.25 ENSDART00000172689
dopamine receptor D4a
chr2_-_54039293 2.24 ENSDART00000166013
abhydrolase domain containing 8a
chr18_+_16125852 2.20 ENSDART00000061106
basic helix-loop-helix family, member e41
chr5_-_16274058 2.19 ENSDART00000090684
kringle containing transmembrane protein 1
chr3_+_32789605 2.18 ENSDART00000171895
TBC1 domain family, member 10b
chr18_-_25177230 2.18 ENSDART00000013363
solute carrier organic anion transporter family, member 3A1
chr6_-_11780070 2.18 ENSDART00000151195
membrane-associated ring finger (C3HC4) 7
chr3_-_30434016 2.17 ENSDART00000150958
leucine rich repeat containing 4Ba
chr5_-_10002260 2.17 ENSDART00000141831
si:ch73-266o15.4
chr4_+_2482046 2.17 ENSDART00000103371
zinc finger, DHHC-type containing 17
chr20_+_474288 2.16 ENSDART00000026794
5'-nucleotidase domain containing 1
chr17_-_51829310 2.16 ENSDART00000154544
numb homolog (Drosophila)
chr10_-_27223827 2.16 ENSDART00000185138
autism susceptibility candidate 2a
chr24_-_21498802 2.16 ENSDART00000181235
ENSDART00000153695
ATPase phospholipid transporting 8A2
chr6_-_957830 2.14 ENSDART00000090019
ENSDART00000184286
zinc finger E-box binding homeobox 2b
chr10_-_25069155 2.14 ENSDART00000078226
ENSDART00000181941
melatonin receptor 1Bb
chr22_-_29586608 2.13 ENSDART00000059869
adrenoceptor alpha 2A
chr20_+_715739 2.12 ENSDART00000136768
myosin VIa
chr20_-_31067306 2.11 ENSDART00000014163
fibronectin type III domain containing 1
chr6_+_52350443 2.09 ENSDART00000151612
ENSDART00000151349
si:ch211-239j9.1
chr11_-_45385803 2.09 ENSDART00000173329
trafficking protein particle complex 10
chr22_+_20461488 2.08 ENSDART00000135984
one cut homeobox 3a
chr19_-_22488952 2.07 ENSDART00000179856
ENSDART00000141503
plectin a
chr7_+_73593814 2.06 ENSDART00000110544
zinc finger protein 219
chr24_+_16393302 2.05 ENSDART00000188670
ENSDART00000081759
ENSDART00000177790
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr1_-_47771742 2.05 ENSDART00000101079
neuralized E3 ubiquitin protein ligase 1Aa
chr15_-_47929455 2.05 ENSDART00000064462
proteasome subunit alpha 6, like
chr4_+_3980247 2.05 ENSDART00000049194
G protein-coupled receptor 37b
chr15_-_41807371 2.03 ENSDART00000156819
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36b
chr21_+_15870752 1.99 ENSDART00000122015
family with sequence similarity 169, member Ab
chr7_+_48288762 1.98 ENSDART00000083569
ornithine decarboxylase antizyme 2b
chr1_-_8428736 1.98 ENSDART00000138435
ENSDART00000121823
synaptogyrin 3b
chr20_-_1314537 1.97 ENSDART00000144288
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr9_+_8929764 1.96 ENSDART00000102562
ankyrin repeat domain 10b
chr16_-_42151909 1.94 ENSDART00000160950
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr17_+_15983247 1.94 ENSDART00000154275
calmin
chr25_-_12203952 1.93 ENSDART00000158204
ENSDART00000091727
neurotrophic tyrosine kinase, receptor, type 3a
chr17_-_45254585 1.92 ENSDART00000185507
ENSDART00000172080
tau tubulin kinase 2a

Network of associatons between targets according to the STRING database.

First level regulatory network of zbtb14

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.8 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
1.7 5.0 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
1.4 4.3 GO:0044406 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
1.4 8.3 GO:0006544 glycine metabolic process(GO:0006544) glycine biosynthetic process(GO:0006545)
1.4 4.1 GO:0072579 establishment of synaptic specificity at neuromuscular junction(GO:0007529) molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
1.3 11.9 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
1.2 3.5 GO:0008292 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.9 2.8 GO:1903334 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.9 3.6 GO:0006844 acyl carnitine transport(GO:0006844)
0.8 4.2 GO:0061551 trigeminal ganglion development(GO:0061551)
0.8 4.0 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.8 2.4 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.7 13.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.7 2.0 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.7 3.3 GO:0051145 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
0.7 2.6 GO:0070317 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.6 3.7 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.6 4.2 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.6 3.0 GO:0032978 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.6 7.3 GO:0048899 anterior lateral line development(GO:0048899)
0.5 3.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.5 2.5 GO:0021731 trigeminal motor nucleus development(GO:0021731)
0.5 1.5 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.5 1.9 GO:0071733 establishment of mitotic sister chromatid cohesion(GO:0034087) establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169) transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.5 2.8 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.4 0.9 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.4 4.4 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.4 2.1 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.4 3.4 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.4 8.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.4 2.7 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.4 5.2 GO:0051967 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.4 7.1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.4 3.3 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.4 2.2 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.4 3.5 GO:0032288 myelin assembly(GO:0032288)
0.3 8.3 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.3 0.6 GO:1904861 excitatory synapse assembly(GO:1904861)
0.3 11.8 GO:0046847 filopodium assembly(GO:0046847)
0.3 0.6 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.3 39.6 GO:0002088 lens development in camera-type eye(GO:0002088)
0.3 5.1 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.3 1.3 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.2 10.2 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.2 4.6 GO:1990090 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.2 1.0 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.2 5.7 GO:1990798 pancreas regeneration(GO:1990798)
0.2 3.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 2.5 GO:0030431 sleep(GO:0030431)
0.2 1.3 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.2 0.9 GO:0048914 anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940) trabecula formation(GO:0060343) heart trabecula formation(GO:0060347)
0.2 1.5 GO:0006833 water transport(GO:0006833)
0.2 2.7 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.2 1.1 GO:0032608 interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648) positive regulation of interferon-beta production(GO:0032728)
0.2 0.9 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.2 2.8 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.2 3.3 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.2 3.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 1.4 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.2 1.0 GO:0060251 memory(GO:0007613) regulation of glial cell proliferation(GO:0060251)
0.2 1.3 GO:1990402 embryonic liver development(GO:1990402)
0.2 6.7 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.2 8.1 GO:0036269 swimming behavior(GO:0036269)
0.2 2.8 GO:0060078 regulation of postsynaptic membrane potential(GO:0060078)
0.1 1.3 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.1 2.8 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.1 1.6 GO:0035588 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1 2.6 GO:0016584 nucleosome positioning(GO:0016584)
0.1 1.3 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.1 2.2 GO:0071715 icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571)
0.1 4.1 GO:0007006 mitochondrial membrane organization(GO:0007006)
0.1 1.6 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.1 2.7 GO:0036294 cellular response to decreased oxygen levels(GO:0036294) cellular response to hypoxia(GO:0071456)
0.1 2.0 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 4.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 1.8 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 1.0 GO:0043217 myelin maintenance(GO:0043217)
0.1 2.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 4.6 GO:0032456 endocytic recycling(GO:0032456)
0.1 1.5 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.1 1.2 GO:0050688 regulation of defense response to virus(GO:0050688)
0.1 2.1 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.1 0.3 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.1 1.6 GO:0016203 muscle attachment(GO:0016203)
0.1 2.8 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.4 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.1 1.5 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 4.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 2.2 GO:0021884 forebrain neuron development(GO:0021884)
0.1 0.9 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.4 GO:0030575 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.1 5.5 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.1 2.0 GO:0006595 polyamine metabolic process(GO:0006595)
0.1 2.0 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 10.1 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 1.4 GO:0039014 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014) nephron tubule epithelial cell differentiation(GO:0072160)
0.1 5.6 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.1 1.0 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 3.0 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 0.8 GO:0006670 sphingosine metabolic process(GO:0006670)
0.1 2.2 GO:0045332 phospholipid translocation(GO:0045332)
0.1 1.1 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 0.5 GO:0051013 microtubule severing(GO:0051013)
0.1 2.8 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 2.1 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.1 1.0 GO:0051693 actin filament capping(GO:0051693)
0.1 11.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.6 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 0.6 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.0 1.4 GO:0006829 zinc II ion transport(GO:0006829)
0.0 4.2 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 2.0 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 8.1 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 1.2 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 1.5 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 1.7 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.4 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 1.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 2.1 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.7 GO:0001569 patterning of blood vessels(GO:0001569)
0.0 3.2 GO:0060027 convergent extension involved in gastrulation(GO:0060027)
0.0 1.9 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.8 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 2.6 GO:0048675 axon extension(GO:0048675)
0.0 2.1 GO:0030903 notochord development(GO:0030903)
0.0 5.3 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 1.4 GO:0021545 cranial nerve development(GO:0021545)
0.0 1.1 GO:0007416 synapse assembly(GO:0007416)
0.0 3.4 GO:0007601 visual perception(GO:0007601)
0.0 1.7 GO:0050769 positive regulation of neurogenesis(GO:0050769)
0.0 0.1 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.2 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 1.2 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 3.6 GO:0044782 cilium organization(GO:0044782)
0.0 1.6 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 1.0 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.4 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 1.5 GO:0007043 cell-cell junction assembly(GO:0007043)
0.0 0.4 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 2.1 GO:0001889 liver development(GO:0001889)
0.0 0.6 GO:0009948 anterior/posterior axis specification(GO:0009948)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.8 GO:0005960 glycine cleavage complex(GO:0005960)
1.1 16.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.9 2.8 GO:0072380 TRC complex(GO:0072380)
0.9 2.7 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.8 4.0 GO:0030314 junctional membrane complex(GO:0030314)
0.7 7.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.6 3.2 GO:1990071 TRAPPII protein complex(GO:1990071)
0.6 3.4 GO:0070062 extracellular exosome(GO:0070062)
0.5 11.9 GO:0035371 microtubule plus-end(GO:0035371)
0.5 13.1 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.4 3.5 GO:0033010 paranodal junction(GO:0033010)
0.4 10.2 GO:0043195 terminal bouton(GO:0043195)
0.4 1.2 GO:0010369 chromocenter(GO:0010369)
0.4 1.5 GO:0005588 collagen type V trimer(GO:0005588)
0.3 3.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.3 7.8 GO:0031594 neuromuscular junction(GO:0031594)
0.3 3.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.3 5.1 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.2 3.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 1.0 GO:0008091 spectrin(GO:0008091)
0.2 3.0 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 2.0 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 7.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 4.0 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 5.4 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.2 1.6 GO:0036449 microtubule minus-end(GO:0036449)
0.1 2.1 GO:0030056 hemidesmosome(GO:0030056)
0.1 1.9 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 2.3 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 2.0 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.1 4.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 14.8 GO:0099572 postsynaptic specialization(GO:0099572)
0.1 1.3 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.4 GO:0098978 glutamatergic synapse(GO:0098978)
0.1 0.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 2.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 4.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 2.3 GO:0042734 presynaptic membrane(GO:0042734)
0.1 0.8 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 8.4 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 1.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 2.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 0.9 GO:0005922 connexon complex(GO:0005922)
0.1 5.0 GO:0030141 secretory granule(GO:0030141)
0.1 10.2 GO:0034703 cation channel complex(GO:0034703)
0.1 4.4 GO:0048475 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.1 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 4.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.2 GO:0008278 cohesin complex(GO:0008278)
0.0 1.0 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 3.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.0 GO:0035102 PRC1 complex(GO:0035102)
0.0 8.6 GO:0005911 cell-cell junction(GO:0005911)
0.0 3.5 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 2.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 5.2 GO:0030424 axon(GO:0030424)
0.0 0.4 GO:0015030 Cajal body(GO:0015030)
0.0 2.8 GO:0005802 trans-Golgi network(GO:0005802)
0.0 27.3 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 1.1 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.5 GO:0030496 midbody(GO:0030496)
0.0 0.4 GO:0070822 Sin3-type complex(GO:0070822)
0.0 1.6 GO:0005770 late endosome(GO:0005770)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
1.4 4.1 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.9 2.8 GO:0042165 neurotransmitter binding(GO:0042165) acetylcholine binding(GO:0042166)
0.9 3.6 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.8 16.0 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.8 4.6 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.7 4.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.7 2.8 GO:0008459 chondroitin 6-sulfotransferase activity(GO:0008459)
0.7 2.0 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.7 2.7 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.6 7.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.6 3.8 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.6 5.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.6 3.7 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.5 4.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.5 2.0 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.5 7.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.5 2.9 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.5 39.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.5 1.4 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.4 5.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.4 1.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.4 8.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.4 2.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.4 2.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.3 8.3 GO:0008483 transaminase activity(GO:0008483)
0.3 1.3 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2 4.4 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.2 8.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 1.6 GO:0030274 LIM domain binding(GO:0030274)
0.2 1.6 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.2 2.9 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.2 4.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 1.7 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.2 3.5 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.2 2.7 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 1.4 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.2 2.8 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.2 1.4 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.2 0.8 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.2 4.6 GO:0031267 small GTPase binding(GO:0031267)
0.2 1.6 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 7.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 0.9 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.2 1.6 GO:0030507 spectrin binding(GO:0030507)
0.2 3.3 GO:0001671 ATPase activator activity(GO:0001671)
0.2 8.6 GO:0044325 ion channel binding(GO:0044325)
0.1 1.8 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 2.1 GO:0030506 ankyrin binding(GO:0030506)
0.1 9.0 GO:0019905 syntaxin binding(GO:0019905)
0.1 3.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 5.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 2.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 3.2 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.1 2.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 8.3 GO:0019903 protein phosphatase binding(GO:0019903)
0.1 2.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 2.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 3.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 3.0 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 2.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.0 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 2.8 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 2.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 1.5 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 0.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 4.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 3.1 GO:0019003 GDP binding(GO:0019003)
0.1 2.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.4 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 1.5 GO:0005080 protein kinase C binding(GO:0005080)
0.1 3.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 2.0 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.1 0.9 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 6.4 GO:0045296 cadherin binding(GO:0045296)
0.1 0.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 8.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.4 GO:0004960 thromboxane receptor activity(GO:0004960)
0.1 0.2 GO:0043185 vascular endothelial growth factor receptor 3 binding(GO:0043185)
0.1 3.0 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.5 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.0 GO:0002039 p53 binding(GO:0002039)
0.1 0.6 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.1 2.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 5.0 GO:0005516 calmodulin binding(GO:0005516)
0.0 1.1 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.0 4.8 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 12.9 GO:0005096 GTPase activator activity(GO:0005096)
0.0 2.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 1.8 GO:0000146 microfilament motor activity(GO:0000146) actin-dependent ATPase activity(GO:0030898)
0.0 4.3 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 1.5 GO:0000149 SNARE binding(GO:0000149)
0.0 0.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 1.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 25.1 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.8 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 1.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.4 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.1 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 1.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 4.1 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 2.2 GO:0000287 magnesium ion binding(GO:0000287)
0.0 1.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.1 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.6 GO:0019838 growth factor binding(GO:0019838)
0.0 3.7 GO:0008017 microtubule binding(GO:0008017)
0.0 3.0 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 1.7 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 13.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.3 5.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.3 4.7 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.2 2.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 1.4 PID RHOA PATHWAY RhoA signaling pathway
0.1 1.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 3.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 3.9 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 2.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 7.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 5.2 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 3.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 0.8 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 3.2 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.1 1.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 2.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.0 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.5 1.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 2.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.2 1.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 4.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 5.4 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.2 3.9 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.2 3.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.2 0.8 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.2 2.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 2.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 3.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 0.9 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 3.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 6.7 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.1 3.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 3.7 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.1 1.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 5.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 0.7 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 1.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.1 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 2.2 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.2 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.0 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA