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PRJEB1986: zebrafish developmental stages transcriptome

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Results for wt1a+wt1b

Z-value: 2.02

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Transcription factors associated with wt1a+wt1b

Gene Symbol Gene ID Gene Info
ENSDARG00000007990 WT1 transcription factor b
ENSDARG00000031420 WT1 transcription factor a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
wt1adr11_v1_chr25_-_15214161_152141610.716.7e-04Click!
wt1bdr11_v1_chr18_-_45617146_45617146-0.077.8e-01Click!

Activity profile of wt1a+wt1b motif

Sorted Z-values of wt1a+wt1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_43056153 6.75 ENSDART00000186377
prion protein a
chr4_+_68562464 6.49 ENSDART00000192954

chr2_-_22535 6.10 ENSDART00000157877

chr20_-_25518488 5.99 ENSDART00000186993
cytochrome P450, family 2, subfamily N, polypeptide 13
chr7_-_10606 5.53 ENSDART00000192650
ENSDART00000186761

chr5_+_36614196 5.17 ENSDART00000150574
neuro-oncological ventral antigen 1
chr25_+_10811551 5.03 ENSDART00000167730
alanyl (membrane) aminopeptidase b
chr25_+_24250247 4.63 ENSDART00000064646
transmembrane protein 86A
chr1_-_59422880 4.57 ENSDART00000167244
si:ch211-188p14.2
chr9_-_54001502 4.44 ENSDART00000085253
midline 1
chr7_+_67325933 4.43 ENSDART00000170575
ENSDART00000183342
nuclear factor of activated T cells 5b
chr8_+_2656231 4.20 ENSDART00000160833
family with sequence similarity 102, member Aa
chr23_-_637347 4.13 ENSDART00000132175
L1 cell adhesion molecule, paralog b
chr4_-_68563862 4.11 ENSDART00000182970

chr17_+_27456804 4.01 ENSDART00000017756
ENSDART00000181461
ENSDART00000180178
cathepsin L.1
chr11_+_6819050 3.90 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr2_+_58221163 3.80 ENSDART00000157939

chr8_-_22739757 3.76 ENSDART00000182167
ENSDART00000171891
IQ motif and Sec7 domain 2a
chr9_-_33725972 3.74 ENSDART00000028225
monoamine oxidase
chr21_-_39058490 3.66 ENSDART00000114885
aldehyde dehydrogenase 3 family, member A2b
chr23_-_3703569 3.65 ENSDART00000143731
protein kinase C and casein kinase substrate in neurons 1a
chr15_-_37543591 3.62 ENSDART00000180400
lysine (K)-specific methyltransferase 2Bb
chr8_+_26268100 3.62 ENSDART00000138882
solute carrier family 26, member 6
chr3_-_11624694 3.61 ENSDART00000127157
hepatic leukemia factor a
chr21_+_1143141 3.50 ENSDART00000178294

chr13_-_638485 3.44 ENSDART00000066080
ENSDART00000128969
slit homolog 1a (Drosophila)
chr12_+_48744016 3.41 ENSDART00000175518

chr13_-_27767330 3.41 ENSDART00000131631
ENSDART00000112553
ENSDART00000189911
regulating synaptic membrane exocytosis 1a
chr21_+_11468642 3.38 ENSDART00000041869
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr3_+_32526799 3.37 ENSDART00000185755
si:ch73-367p23.2
chr18_+_3004572 3.32 ENSDART00000190328

chr7_-_6592142 3.30 ENSDART00000160137
potassium inwardly-rectifying channel, subfamily J, member 10a
chr25_+_34984333 3.28 ENSDART00000154760
coiled-coil domain containing 136b
chr3_+_19299309 3.28 ENSDART00000046297
ENSDART00000146955
low density lipoprotein receptor a
chr11_+_36989696 3.25 ENSDART00000045888
transketolase a
chr19_+_41701660 3.22 ENSDART00000033362
GATA zinc finger domain containing 2B
chr5_+_6617401 3.22 ENSDART00000060532
zgc:110796
chr5_+_9348284 3.21 ENSDART00000149417
T-cell acute lymphocytic leukemia 2
chr23_+_44665230 3.21 ENSDART00000144958
calmodulin binding transcription activator 2
chr4_-_77557279 3.19 ENSDART00000180113

chr7_+_10701938 3.16 ENSDART00000158162
aryl-hydrocarbon receptor nuclear translocator 2
chr16_-_22022456 3.13 ENSDART00000140175
si:dkey-71b5.3
chr18_+_660578 3.11 ENSDART00000161203
si:dkey-205h23.2
chr6_-_52428826 2.99 ENSDART00000047399
matrix metallopeptidase 24
chr9_-_30363770 2.97 ENSDART00000147030
synaptotagmin-like 5
chr7_-_57949117 2.96 ENSDART00000138803
ankyrin 2b, neuronal
chr8_+_8166285 2.94 ENSDART00000147940
plexin B3
chr9_-_54840124 2.92 ENSDART00000137214
ENSDART00000085693
glycoprotein M6Bb
chr11_-_103136 2.89 ENSDART00000173308
ENSDART00000162982
engulfment and cell motility 2
chr6_+_2271559 2.86 ENSDART00000165223
pre-B-cell leukemia homeobox 1b
chr2_+_48073972 2.80 ENSDART00000186442
Kruppel-like factor 6b
chr4_+_55758103 2.78 ENSDART00000185964

chr23_-_30785382 2.63 ENSDART00000136156
ENSDART00000131285
myelin transcription factor 1a
chr16_-_280835 2.63 ENSDART00000190541

chr14_-_2933185 2.62 ENSDART00000161677
ENSDART00000162446
ENSDART00000109378
si:dkey-201i24.6
chr6_-_60104628 2.61 ENSDART00000057463
ENSDART00000169188
prostate transmembrane protein, androgen induced 1
chr14_+_30910114 2.60 ENSDART00000187166
ENSDART00000078187
forkhead box O4
chr8_+_26268726 2.55 ENSDART00000180883
solute carrier family 26, member 6
chr11_-_44030962 2.55 ENSDART00000171910

chr5_-_13086616 2.53 ENSDART00000051664
yippee-like 1
chr13_+_13693722 2.52 ENSDART00000110509
si:ch211-194c3.5
chr1_+_54677173 2.49 ENSDART00000114705
G protein-coupled receptor, class C, group 5, member Bb
chr25_+_35774544 2.48 ENSDART00000034737
ENSDART00000188162
copine VIII
chr3_+_50312422 2.48 ENSDART00000157689
growth arrest-specific 7a
chr16_+_36650984 2.45 ENSDART00000156780
collagen, type VI, alpha 4a
chr22_-_18112374 2.45 ENSDART00000191154
neurocan b
chr5_+_51443009 2.45 ENSDART00000083350
Ras protein-specific guanine nucleotide-releasing factor 2b
chr13_-_31166544 2.44 ENSDART00000146250
ENSDART00000132129
ENSDART00000139591
mitogen-activated protein kinase 8a
chr17_+_44756247 2.43 ENSDART00000153773
CLOCK-interacting pacemaker a
chr13_-_49666615 2.42 ENSDART00000148083
translocase of outer mitochondrial membrane 20
chr24_-_38110779 2.41 ENSDART00000147783
c-reactive protein, pentraxin-related
chr10_+_44940693 2.41 ENSDART00000157515
cyclin and CBS domain divalent metal cation transport mediator 4a
chr22_-_600016 2.40 ENSDART00000086434
transmembrane and coiled-coil domain family 2
chr25_-_207214 2.40 ENSDART00000193448

chr6_+_58492201 2.36 ENSDART00000156375
potassium voltage-gated channel, KQT-like subfamily, member 2b
chr19_+_164013 2.32 ENSDART00000167379
capping protein regulator and myosin 1 linker 1
chr6_+_6491013 2.32 ENSDART00000140827
B cell CLL/lymphoma 11Ab
chr5_+_9382301 2.32 ENSDART00000124017
UDP glucuronosyltransferase 2 family, polypeptide A7
chr3_-_30861177 2.31 ENSDART00000154811
SH3 and multiple ankyrin repeat domains 1
chr17_-_20711735 2.29 ENSDART00000150056
ankyrin 3b
chr10_+_32561317 2.27 ENSDART00000109029
microtubule-associated protein 6a
chr15_-_33925851 2.26 ENSDART00000187807
ENSDART00000187780
myelin associated glycoprotein
chr20_+_46741074 2.25 ENSDART00000145294
si:ch211-57i17.1
chr21_+_11468934 2.24 ENSDART00000126045
ENSDART00000129744
ENSDART00000102368
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr3_-_62380146 2.24 ENSDART00000155853
G protein-coupled receptor, class C, group 5, member Ba
chr19_+_935565 2.22 ENSDART00000113368
ring finger protein 5
chr25_+_22683640 2.17 ENSDART00000131993
Usher syndrome 1C
chr17_-_22048233 2.17 ENSDART00000155203
tau tubulin kinase 1b
chr11_-_32723851 2.17 ENSDART00000155592
protocadherin 17
chr14_-_2369849 2.15 ENSDART00000180422
ENSDART00000189731
ENSDART00000111748
protocadherin b
chr16_-_13613475 2.12 ENSDART00000139102
D site albumin promoter binding protein b
chr10_-_24343507 2.12 ENSDART00000002974
phosphatidylinositol transfer protein, alpha b
chr5_-_68022631 2.11 ENSDART00000143199
WAS protein family, member 3a
chr2_+_7192966 2.09 ENSDART00000142735
si:ch211-13f8.1
chr11_+_40649412 2.09 ENSDART00000043016
ENSDART00000134560
solute carrier family 45, member 1
chr10_+_8885769 2.09 ENSDART00000139466
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 2
chr3_-_1190132 2.08 ENSDART00000149709
single-pass membrane protein with aspartate-rich tail 1a
chr13_+_1100197 2.06 ENSDART00000139560
protein phosphatase 3, regulatory subunit B, alpha a
chr21_+_28958471 2.06 ENSDART00000144331
ENSDART00000005929
protein phosphatase 3, catalytic subunit, alpha isozyme
chr2_-_54639964 2.06 ENSDART00000100103
acyl-CoA synthetase short chain family member 2 like
chr12_+_2522642 2.04 ENSDART00000152567
FERM and PDZ domain containing 2
chr21_-_22485847 2.04 ENSDART00000162860
myosin VB
chr23_+_29908348 2.04 ENSDART00000186622
ENSDART00000150174
si:ch73-236e11.2
chr25_-_19395476 2.01 ENSDART00000182622
microtubule-associated protein 1Ab
chr19_+_48111285 2.01 ENSDART00000169420
NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 2
chr2_-_57076687 1.99 ENSDART00000161523
solute carrier family 25, member 42
chr19_+_33701366 1.99 ENSDART00000162517
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_-_18446483 1.98 ENSDART00000180027
si:dkey-215k6.1
chr25_+_35706493 1.96 ENSDART00000176741
kinesin family member 21A
chr7_+_74141297 1.96 ENSDART00000164992
RNA binding protein with multiple splicing
chr20_-_1268863 1.95 ENSDART00000109321
ENSDART00000027119
large tumor suppressor kinase 1
chr5_+_37343643 1.94 ENSDART00000163993
ENSDART00000164459
ENSDART00000167006
ENSDART00000128122
ENSDART00000183720
kelch-like family member 13
chr3_-_49504023 1.92 ENSDART00000168108
protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a
chr11_+_25459697 1.91 ENSDART00000161481
opsin 1 (cone pigments), short-wave-sensitive 2
chr11_+_41560792 1.91 ENSDART00000127292
potassium voltage-gated channel, shaker-related subfamily, beta member 2 a
chr21_+_11139175 1.90 ENSDART00000169024
alanine--glyoxylate aminotransferase 2
chr19_+_33701734 1.89 ENSDART00000123270
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_+_6576940 1.88 ENSDART00000138135
V-set and immunoglobulin domain containing 8b
chr14_-_1565317 1.88 ENSDART00000169496

chr23_+_43834376 1.86 ENSDART00000148989
si:ch211-149b19.4
chr16_+_1803462 1.85 ENSDART00000183974
glutamate ionotropic receptor kainate type subunit 2
chr5_-_31928913 1.84 ENSDART00000142919
slingshot protein phosphatase 1b
chr2_+_33382648 1.83 ENSDART00000137207
ENSDART00000098831
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr22_+_883678 1.82 ENSDART00000140588
serine/threonine kinase 38b
chr15_-_30816370 1.81 ENSDART00000142982
ENSDART00000050649
ENSDART00000136901
ENSDART00000100194
musashi RNA-binding protein 2b
chr19_+_233143 1.80 ENSDART00000175273
synaptic Ras GTPase activating protein 1a
chr4_-_38476901 1.78 ENSDART00000167124
si:ch211-209n20.59
chr5_-_46273938 1.78 ENSDART00000080033
si:ch211-130m23.3
chr8_+_22485956 1.76 ENSDART00000099960
si:ch211-261n11.7
chr15_-_42736433 1.75 ENSDART00000154379
si:ch211-181d7.1
chr8_+_36666789 1.74 ENSDART00000144255
MAGI family member, X-linked b
chr1_-_37087966 1.73 ENSDART00000172111
ENSDART00000160056
nuclear receptor subfamily 3, group C, member 2
chr19_+_63567 1.73 ENSDART00000165657
ENSDART00000165183
zinc fingers and homeoboxes 2b
chr5_-_6433577 1.72 ENSDART00000160439

chr3_+_7617353 1.72 ENSDART00000165551
zgc:109949
chr18_-_33344 1.72 ENSDART00000129125
phosphodiesterase 8A
chr18_-_1258777 1.72 ENSDART00000077106
ENSDART00000129065
UDP glucuronosyltransferase 5 family, polypeptide F1
chr10_+_10738880 1.72 ENSDART00000004181
solute carrier family 27 (fatty acid transporter), member 4
chr19_-_6193448 1.71 ENSDART00000151405
Ets2 repressor factor
chr14_-_12837432 1.70 ENSDART00000178444
glutamate receptor, ionotropic, AMPA 3b
chr20_-_52928541 1.69 ENSDART00000162812
farnesyl-diphosphate farnesyltransferase 1
chr1_-_411331 1.69 ENSDART00000092524
RAS p21 protein activator 3
chr3_+_32526263 1.68 ENSDART00000150897
si:ch73-367p23.2
chr2_+_49232559 1.68 ENSDART00000154285
ENSDART00000175147
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba
chr22_+_1539373 1.67 ENSDART00000172104
si:ch211-255f4.7
chr12_-_48943467 1.66 ENSDART00000191829

chr21_-_24865454 1.65 ENSDART00000142907
immunoglobulin superfamily, member 9Bb
chr25_-_37501371 1.64 ENSDART00000160498

chr9_+_48943471 1.64 ENSDART00000125090
serine threonine kinase 39
chr21_-_22114625 1.62 ENSDART00000177426
ENSDART00000135410
ELMO/CED-12 domain containing 1
chr16_+_4838808 1.61 ENSDART00000179363
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr10_+_439692 1.58 ENSDART00000147740
zinc finger, DHHC-type containing 8a
chr9_-_2572790 1.55 ENSDART00000135076
ENSDART00000016710
secernin 3
chr16_-_42152145 1.54 ENSDART00000038748
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr20_+_715739 1.54 ENSDART00000136768
myosin VIa
chr10_+_45128375 1.53 ENSDART00000164805
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr2_-_9646857 1.53 ENSDART00000056901
zgc:153615
chr23_+_27912079 1.52 ENSDART00000171859

chr14_-_12837052 1.52 ENSDART00000165004
ENSDART00000043180
glutamate receptor, ionotropic, AMPA 3b
chr17_+_46387086 1.52 ENSDART00000157079
si:dkey-206p8.1
chr14_+_22172047 1.51 ENSDART00000114750
ENSDART00000148259
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr8_+_23165749 1.50 ENSDART00000063057
DnaJ (Hsp40) homolog, subfamily C, member 5aa
chr7_-_29534001 1.50 ENSDART00000124028
annexin A2b
chr5_-_67145505 1.50 ENSDART00000011295
retinal outer segment membrane protein 1a
chr15_+_47418565 1.48 ENSDART00000155709
ClpB homolog, mitochondrial AAA ATPase chaperonin
chr7_-_51627019 1.47 ENSDART00000174111
NHS-like 2
chr3_+_22079219 1.46 ENSDART00000122782
KAT8 regulatory NSL complex subunit 1b
chr8_+_51958968 1.45 ENSDART00000139509
ENSDART00000186544
guanine nucleotide binding protein (G protein), alpha 14a
chr19_-_617246 1.44 ENSDART00000062551
cytochrome P450, family 51
chr16_+_10918252 1.44 ENSDART00000172949
POU class 2 homeobox 2a
chr6_-_58828113 1.44 ENSDART00000180934
kinesin family member 5A, b
chr3_-_36944749 1.43 ENSDART00000154501
contactin associated protein 1
chr2_+_48074243 1.42 ENSDART00000056291
Kruppel-like factor 6b
chr8_-_53490376 1.41 ENSDART00000158789
choline dehydrogenase
chr24_-_38644937 1.40 ENSDART00000170194
solute carrier family 6, member 16b
chr11_-_97817 1.39 ENSDART00000092903
engulfment and cell motility 2
chr17_-_19828505 1.38 ENSDART00000154745
formin 2a
chr9_+_13714379 1.38 ENSDART00000017593
ENSDART00000145503
transmembrane protein 237a
chr17_+_11507131 1.36 ENSDART00000013170
kinesin family member 26Ba
chr6_-_30859656 1.36 ENSDART00000156235
phosphodiesterase 4B, cAMP-specific a
chr4_+_3980247 1.34 ENSDART00000049194
G protein-coupled receptor 37b
chr8_+_7740004 1.34 ENSDART00000170184
ENSDART00000187811
FYVE, RhoGEF and PH domain containing 1
chr2_-_24068848 1.34 ENSDART00000145526
solute carrier family 12 (potassium/chloride transporter), member 7a
chr2_-_11912347 1.34 ENSDART00000023851
abhydrolase domain containing 3
chr20_+_13969414 1.34 ENSDART00000049864
retinal degeneration 3
chr12_+_48511605 1.34 ENSDART00000168389
Rho GTPase activating protein 44
chr3_+_12322170 1.33 ENSDART00000161227
GLIS family zinc finger 2b
chr23_+_19564392 1.33 ENSDART00000144746
ATPase H+ transporting accessory protein 1 like b
chr20_-_51727860 1.33 ENSDART00000147044
BRO1 domain and CAAX motif containing
chr6_-_7776612 1.32 ENSDART00000190269
myosin, heavy chain 9a, non-muscle
chr2_+_38924975 1.32 ENSDART00000109219
RAS (RAD and GEM)-like GTP binding 2
chr11_+_45461419 1.31 ENSDART00000173424
son of sevenless homolog 1 (Drosophila)
chr9_-_1434484 1.30 ENSDART00000093412
oxysterol binding protein-like 6
chr12_-_314899 1.30 ENSDART00000066579
6-pyruvoyltetrahydropterin synthase
chr10_-_33156789 1.30 ENSDART00000192268
ENSDART00000182065
ENSDART00000081170
cut-like homeobox 1a
chr6_-_442163 1.29 ENSDART00000163564
ENSDART00000189134
ENSDART00000169789
GRB2-related adaptor protein 2b
chr6_-_16406210 1.29 ENSDART00000012023
Fas apoptotic inhibitory molecule b
chr14_+_2243 1.29 ENSDART00000191193
cytokine like 1
chr14_-_962171 1.27 ENSDART00000010773
acyl-CoA synthetase long chain family member 1b
chr16_-_12953739 1.27 ENSDART00000103894
calcium channel, voltage-dependent, gamma subunit 8b

Network of associatons between targets according to the STRING database.

First level regulatory network of wt1a+wt1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
1.0 6.2 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
1.0 4.0 GO:0006837 serotonin transport(GO:0006837) serotonin uptake(GO:0051610)
0.8 2.3 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.6 3.2 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.6 2.4 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.6 3.0 GO:0036371 protein localization to T-tubule(GO:0036371)
0.6 2.3 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.6 0.6 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.5 3.3 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.5 2.0 GO:0003245 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.5 1.5 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.5 3.3 GO:0036268 swimming(GO:0036268)
0.5 1.4 GO:0019695 choline metabolic process(GO:0019695)
0.5 1.8 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.4 1.7 GO:0071387 cellular response to cortisol stimulus(GO:0071387)
0.4 6.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.4 3.7 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.4 2.6 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.3 2.1 GO:0019427 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.3 7.6 GO:0045773 positive regulation of axon extension(GO:0045773)
0.3 5.9 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.3 1.3 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.3 1.5 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.3 2.3 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.3 2.0 GO:0090177 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.3 1.3 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.3 1.3 GO:0061438 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.3 1.0 GO:0070317 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.3 3.3 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.2 1.2 GO:0070650 actin filament bundle distribution(GO:0070650)
0.2 3.1 GO:0048798 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.2 5.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 0.7 GO:0032369 negative regulation of lipid transport(GO:0032369)
0.2 1.9 GO:0071326 cellular response to carbohydrate stimulus(GO:0071322) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.2 1.7 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.2 1.7 GO:0043363 nucleate erythrocyte differentiation(GO:0043363)
0.2 5.2 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.2 1.4 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.2 0.8 GO:0006740 NADPH regeneration(GO:0006740)
0.2 0.6 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.2 3.7 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.2 0.9 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.2 1.6 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.2 1.9 GO:0098900 regulation of action potential(GO:0098900)
0.2 2.0 GO:0003139 secondary heart field specification(GO:0003139) regulation of organ growth(GO:0046620)
0.2 0.5 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.2 4.7 GO:0043171 peptide catabolic process(GO:0043171)
0.2 0.5 GO:0098838 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.2 2.4 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.2 0.5 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214) cardiac left ventricle formation(GO:0003218)
0.2 1.2 GO:0071357 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 2.2 GO:0001964 startle response(GO:0001964)
0.1 0.4 GO:0009085 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.1 1.4 GO:0032288 myelin assembly(GO:0032288)
0.1 0.4 GO:0019370 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.1 2.4 GO:0015693 magnesium ion transport(GO:0015693)
0.1 2.4 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.1 2.1 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 1.5 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.1 2.8 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 1.5 GO:0034605 cellular response to heat(GO:0034605)
0.1 3.1 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.1 1.0 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 1.3 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 2.0 GO:1902307 positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 2.0 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 1.3 GO:0039023 pronephric duct morphogenesis(GO:0039023)
0.1 1.3 GO:1902042 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.1 2.1 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 2.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 1.0 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.1 0.9 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 1.8 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.1 2.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 1.0 GO:0046247 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 0.8 GO:0032475 otolith formation(GO:0032475)
0.1 2.9 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.1 3.0 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.1 4.9 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.1 0.6 GO:0007603 phototransduction, visible light(GO:0007603)
0.1 3.0 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 0.9 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.4 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.4 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.9 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 1.4 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 3.2 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.1 0.5 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.1 0.5 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 1.2 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 0.6 GO:0021794 thalamus development(GO:0021794)
0.1 1.2 GO:0031936 nucleosome positioning(GO:0016584) negative regulation of chromatin silencing(GO:0031936)
0.1 1.3 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 0.2 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.1 0.6 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.1 0.5 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.1 1.6 GO:0051289 protein homotetramerization(GO:0051289)
0.1 3.1 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.1 1.0 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 2.2 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1 5.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 1.4 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.1 0.5 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.1 0.7 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.1 0.4 GO:0051673 membrane disruption in other organism(GO:0051673)
0.1 1.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 2.5 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.3 GO:1902868 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.0 0.3 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 5.4 GO:0006909 phagocytosis(GO:0006909)
0.0 2.9 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 1.5 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 1.9 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.4 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 1.9 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.1 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 1.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 2.3 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.7 GO:0022011 myelination in peripheral nervous system(GO:0022011)
0.0 0.2 GO:0002082 regulation of oxidative phosphorylation(GO:0002082) regulation of nucleoside metabolic process(GO:0009118) regulation of ATP metabolic process(GO:1903578)
0.0 0.2 GO:0003210 cardiac atrium formation(GO:0003210)
0.0 0.5 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.2 GO:0034505 tooth mineralization(GO:0034505)
0.0 0.7 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 1.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.8 GO:0050890 cognition(GO:0050890)
0.0 0.9 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.3 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.0 1.4 GO:0045010 actin nucleation(GO:0045010)
0.0 2.4 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108)
0.0 0.5 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.5 GO:0055075 potassium ion homeostasis(GO:0055075)
0.0 0.3 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.8 GO:0046847 filopodium assembly(GO:0046847)
0.0 1.3 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.1 GO:0090435 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.0 1.4 GO:0015914 phospholipid transport(GO:0015914)
0.0 2.0 GO:0030837 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.6 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.7 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 2.1 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 1.1 GO:0007006 mitochondrial membrane organization(GO:0007006)
0.0 0.7 GO:0043523 regulation of neuron apoptotic process(GO:0043523)
0.0 1.1 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 0.7 GO:0060349 bone morphogenesis(GO:0060349)
0.0 0.4 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.7 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 5.6 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 1.2 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 1.2 GO:0007254 JNK cascade(GO:0007254)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 2.9 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 1.1 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 1.4 GO:0060027 convergent extension involved in gastrulation(GO:0060027)
0.0 1.0 GO:0030048 actin filament-based movement(GO:0030048)
0.0 1.1 GO:0070509 calcium ion import(GO:0070509)
0.0 0.9 GO:0030041 actin filament polymerization(GO:0030041)
0.0 2.1 GO:0051321 meiotic cell cycle(GO:0051321)
0.0 0.1 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.0 0.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.7 GO:0070062 extracellular exosome(GO:0070062)
0.4 5.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.3 4.1 GO:0044295 axonal growth cone(GO:0044295)
0.3 2.1 GO:0005955 calcineurin complex(GO:0005955)
0.3 2.4 GO:0043194 axon initial segment(GO:0043194)
0.2 2.2 GO:0032426 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.2 4.4 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 1.3 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.2 2.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.2 3.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.2 1.9 GO:0001669 acrosomal vesicle(GO:0001669)
0.2 3.0 GO:0030315 T-tubule(GO:0030315)
0.2 1.4 GO:0033010 paranodal junction(GO:0033010)
0.2 5.1 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.2 2.1 GO:1990246 uniplex complex(GO:1990246)
0.2 1.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.1 GO:0016586 RSC complex(GO:0016586)
0.1 2.8 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 2.1 GO:0031209 SCAR complex(GO:0031209)
0.1 5.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.1 1.5 GO:0044545 NSL complex(GO:0044545)
0.1 1.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 6.2 GO:0035097 histone methyltransferase complex(GO:0035097)
0.1 0.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.8 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 4.8 GO:0031901 early endosome membrane(GO:0031901)
0.1 3.3 GO:0005902 microvillus(GO:0005902)
0.1 0.9 GO:0043209 myelin sheath(GO:0043209)
0.1 2.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 4.6 GO:0005871 kinesin complex(GO:0005871)
0.1 1.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 1.1 GO:0032039 integrator complex(GO:0032039)
0.0 0.6 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 1.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.0 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 2.1 GO:0008305 integrin complex(GO:0008305)
0.0 1.4 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.0 GO:0035371 microtubule plus-end(GO:0035371)
0.0 4.7 GO:0005884 actin filament(GO:0005884)
0.0 3.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 3.8 GO:0005875 microtubule associated complex(GO:0005875)
0.0 3.1 GO:0016459 myosin complex(GO:0016459)
0.0 2.3 GO:0030027 lamellipodium(GO:0030027)
0.0 0.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.9 GO:0005844 polysome(GO:0005844)
0.0 6.3 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.9 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 2.9 GO:0000786 nucleosome(GO:0000786)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 5.1 GO:0005874 microtubule(GO:0005874)
0.0 1.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 2.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.7 GO:0098802 plasma membrane receptor complex(GO:0098802)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 6.7 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.8 3.3 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.7 3.7 GO:0008131 primary amine oxidase activity(GO:0008131)
0.7 2.0 GO:0080122 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.6 4.6 GO:0016803 ether hydrolase activity(GO:0016803)
0.6 2.8 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.6 1.7 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.5 3.2 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.5 2.6 GO:0070412 R-SMAD binding(GO:0070412)
0.4 1.3 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.4 1.2 GO:0005499 vitamin D binding(GO:0005499)
0.4 1.9 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.4 1.5 GO:0071253 connexin binding(GO:0071253)
0.4 1.1 GO:0015222 serotonin:sodium symporter activity(GO:0005335) serotonin transmembrane transporter activity(GO:0015222)
0.4 3.7 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.3 2.1 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.3 2.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.3 2.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.3 6.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.3 6.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.3 2.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.3 1.1 GO:0072571 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.3 2.1 GO:0015157 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.2 2.4 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 2.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 2.0 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.2 3.4 GO:0048495 Roundabout binding(GO:0048495)
0.2 3.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.2 1.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.2 0.6 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.2 1.0 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.2 0.8 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.2 4.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 1.7 GO:1990239 steroid hormone binding(GO:1990239)
0.2 0.5 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.2 3.0 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 8.4 GO:0044325 ion channel binding(GO:0044325)
0.1 4.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.7 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.1 1.8 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 2.0 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1 2.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.3 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 1.5 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.1 3.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.0 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 3.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.4 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 1.0 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 3.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 4.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 4.7 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.1 0.7 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 3.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 4.9 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 2.0 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 1.0 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 1.9 GO:0008483 transaminase activity(GO:0008483)
0.1 3.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.6 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 2.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.2 GO:0001671 ATPase activator activity(GO:0001671)
0.1 1.0 GO:0035497 cAMP response element binding(GO:0035497)
0.1 1.1 GO:0070411 I-SMAD binding(GO:0070411)
0.1 3.0 GO:0017124 SH3 domain binding(GO:0017124)
0.1 2.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.9 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.0 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 1.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 3.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 5.2 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.3 GO:0042287 MHC protein binding(GO:0042287)
0.0 1.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 1.0 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.3 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 2.3 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 1.9 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 2.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.9 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 1.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.7 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.8 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.2 GO:0005109 frizzled binding(GO:0005109)
0.0 1.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 2.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 1.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 2.7 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.7 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 3.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 4.8 GO:0008134 transcription factor binding(GO:0008134)
0.0 6.4 GO:0008017 microtubule binding(GO:0008017)
0.0 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 7.1 GO:0051015 actin filament binding(GO:0051015)
0.0 0.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.4 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 5.0 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 5.7 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.2 2.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 0.4 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 3.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 2.6 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 1.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 4.4 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 0.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 0.6 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 1.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 1.9 PID AURORA B PATHWAY Aurora B signaling
0.1 1.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 1.6 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 2.8 PID BCR 5PATHWAY BCR signaling pathway
0.0 2.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 2.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.9 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.7 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.7 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.5 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 2.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 1.9 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.2 2.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 2.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 1.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2 2.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.6 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.1 1.2 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 1.8 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 2.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.3 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.1 0.9 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 6.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 2.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 2.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 2.6 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 0.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 1.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 0.6 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 2.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.3 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.4 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 1.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.9 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 2.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.7 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors