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PRJEB1986: zebrafish developmental stages transcriptome

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Results for tfcp2+tfcp2l1+ubp1

Z-value: 2.14

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Transcription factors associated with tfcp2+tfcp2l1+ubp1

Gene Symbol Gene ID Gene Info
ENSDARG00000018000 upstream binding protein 1
ENSDARG00000029497 transcription factor CP2-like 1
ENSDARG00000060306 transcription factor CP2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tfcp2dr11_v1_chr23_-_33679579_336795790.742.6e-04Click!
tfcp2l1dr11_v1_chr9_+_38292947_38292947-0.708.7e-04Click!
ubp1dr11_v1_chr19_+_42806812_42806814-0.662.2e-03Click!

Activity profile of tfcp2+tfcp2l1+ubp1 motif

Sorted Z-values of tfcp2+tfcp2l1+ubp1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr22_+_18349794 7.66 ENSDART00000186580
GATA zinc finger domain containing 2Ab
chr17_+_51743908 7.07 ENSDART00000149039
ENSDART00000148869
ornithine decarboxylase 1
chr8_-_13541514 6.38 ENSDART00000063834
zgc:86586
chr11_-_308838 6.01 ENSDART00000112538
POC1 centriolar protein A
chr16_+_51180938 5.52 ENSDART00000169022
high mobility group nucleosomal binding domain 2
chr5_-_68795063 5.31 ENSDART00000016307
hairy-related 1
chr15_-_5901514 5.26 ENSDART00000155252
si:ch73-281n10.2
chr3_-_27647845 5.17 ENSDART00000151625
si:ch211-157c3.4
chr16_+_29509133 5.03 ENSDART00000112116
cathepsin S, ortholog2, tandem duplicate 1
chr5_-_54712159 4.78 ENSDART00000149207
cyclin B1
chr7_+_57088920 4.63 ENSDART00000024076
secretory carrier membrane protein 2, like
chr20_-_25631256 4.43 ENSDART00000048164
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr3_+_6469754 4.40 ENSDART00000185809
nucleoporin 85
chr23_-_21446985 4.38 ENSDART00000044080
hairy-related 12
chr13_+_28495419 4.37 ENSDART00000025583
fibroblast growth factor 8a
chr11_+_6116503 4.20 ENSDART00000176170
nuclear receptor subfamily 2, group F, member 6b
chr9_-_28939181 4.18 ENSDART00000101276
ENSDART00000135334
erythrocyte membrane protein band 4.1 like 5
chr1_-_53685090 4.14 ENSDART00000162751
exportin 1 (CRM1 homolog, yeast) a
chr25_+_36292057 4.08 ENSDART00000152329
brambleberry
chr12_-_21681509 3.82 ENSDART00000112726
essential meiotic structure-specific endonuclease 1
chr13_+_18533005 3.81 ENSDART00000136024
finTRIM family, member 14-like
chr11_-_36350421 3.77 ENSDART00000141477
proteasome subunit alpha 5
chr4_-_77979432 3.74 ENSDART00000049170
zgc:85975
chr3_-_23512285 3.61 ENSDART00000159151

chr24_+_5935377 3.55 ENSDART00000191989
ENSDART00000185932
ENSDART00000131768
abl-interactor 1a
chr15_+_5901970 3.55 ENSDART00000114134
tryptophan rich basic protein
chr16_-_27224246 3.53 ENSDART00000103257
asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase)
chr13_-_24260609 3.34 ENSDART00000138747
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr16_+_23961276 3.31 ENSDART00000192754
apolipoprotein Eb
chr15_-_34668485 3.30 ENSDART00000186605
BCL2 associated athanogene 6
chr4_+_10066840 3.29 ENSDART00000026492
filamin C, gamma b (actin binding protein 280)
chr22_+_18319230 3.28 ENSDART00000184747
ENSDART00000184649
GATA zinc finger domain containing 2Ab
chr7_+_57089354 3.19 ENSDART00000140702
secretory carrier membrane protein 2, like
chr6_+_41452979 3.19 ENSDART00000007353
WD repeat domain 82
chr4_+_28359718 3.16 ENSDART00000180048
si:ch73-263o4.4
chr4_+_18963822 3.12 ENSDART00000066975
ENSDART00000066973
IMP (inosine 5'-monophosphate) dehydrogenase 1b
chr13_+_24671481 3.09 ENSDART00000001678
ADAM metallopeptidase domain 8a
chr11_-_36350876 3.02 ENSDART00000146495
ENSDART00000020655
proteasome subunit alpha 5
chr17_-_19534474 3.02 ENSDART00000192469
cytochrome P450, family 26, subfamily C, polypeptide 1
chr21_+_25625026 3.00 ENSDART00000134678
ovo-like zinc finger 1b
chr19_-_47570672 2.99 ENSDART00000112155
ribonucleotide reductase M2 polypeptide
chr7_-_26436436 2.96 ENSDART00000019035
ENSDART00000123395
hairy-related 8a
chr7_+_25221757 2.94 ENSDART00000173551
exocyst complex component 6B
chr22_+_19640309 2.93 ENSDART00000061725
ENSDART00000140819
RGM domain family, member D
chr8_-_32805214 2.93 ENSDART00000131597
zgc:194839
chr13_-_25774183 2.91 ENSDART00000046981
PDZ and LIM domain 1 (elfin)
chr23_+_36144487 2.88 ENSDART00000082473
homeobox C3a
chr12_-_10476448 2.83 ENSDART00000106172
Rac family small GTPase 1a
chr21_+_36396864 2.81 ENSDART00000137309
gem (nuclear organelle) associated protein 5
chr5_-_30704390 2.77 ENSDART00000016709
intraflagellar transport 22 homolog (Chlamydomonas)
chr7_-_51648749 2.76 ENSDART00000109055
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr21_+_19648814 2.75 ENSDART00000048581
fibroblast growth factor 10a
chr20_-_39367895 2.74 ENSDART00000136476
ENSDART00000021788
ENSDART00000180784
PDZ binding kinase
chr14_-_31087830 2.69 ENSDART00000002250
heparan sulfate 6-O-sulfotransferase 2
chr15_-_4596623 2.66 ENSDART00000132227
eukaryotic translation initiation factor 4h
chr24_+_13925066 2.64 ENSDART00000134221
ENSDART00000012253
ENSDART00000081595
ENSDART00000136443
EYA transcriptional coactivator and phosphatase 1
chr7_+_38808027 2.64 ENSDART00000052323
harbinger transposase derived 1
chr20_-_25645150 2.63 ENSDART00000063137
si:dkeyp-117h8.4
chr19_-_17304866 2.62 ENSDART00000160433
ENSDART00000190798
ENSDART00000171284
splicing factor 3a, subunit 3
chr19_-_18418763 2.61 ENSDART00000167271
zgc:112966
chr3_-_30488063 2.60 ENSDART00000055393
ENSDART00000151367
mediator complex subunit 25
chr8_-_20914829 2.58 ENSDART00000025356
HAUS augmin-like complex, subunit 5
chr16_-_6424816 2.57 ENSDART00000164864
ENSDART00000141860
membrane bound O-acyltransferase domain containing 1
chr25_+_36292465 2.55 ENSDART00000152649
brambleberry
chr20_-_39391833 2.53 ENSDART00000135149
si:dkey-217m5.8
chr7_+_22792895 2.52 ENSDART00000184407
RNA binding motif protein 4.3
chr18_+_17725410 2.48 ENSDART00000090608
ring finger and SPRY domain containing 1
chr11_+_2202987 2.44 ENSDART00000190008
ENSDART00000173139
homeobox C6b
chr17_+_26815021 2.43 ENSDART00000086885
acetylserotonin O-methyltransferase 2
chr1_-_11104805 2.42 ENSDART00000147648
kinetochore scaffold 1
chr3_-_40162843 2.40 ENSDART00000129664
ENSDART00000025285
developmentally regulated GTP binding protein 2
chr12_+_27024676 2.40 ENSDART00000153104
male-specific lethal 1 homolog b (Drosophila)
chr5_+_20319519 2.39 ENSDART00000004217
coronin, actin binding protein, 1Ca
chr4_-_26035770 2.39 ENSDART00000124514
ubiquitin specific peptidase 44
chr4_+_6032640 2.38 ENSDART00000157487
transcription factor EC
chr7_-_17814118 2.38 ENSDART00000179688
ECSIT signalling integrator
chr22_+_17499905 2.35 ENSDART00000061366
ENSDART00000133793
RAB11B, member RAS oncogene family, a
chr21_+_22892836 2.32 ENSDART00000065565
ALG8, alpha-1,3-glucosyltransferase
chr14_-_33425170 2.31 ENSDART00000124629
ENSDART00000105800
ENSDART00000001318
NFKB activating protein
chr8_-_36554675 2.31 ENSDART00000132804
ENSDART00000078746
coiled-coil domain containing 157
chr22_+_18319666 2.31 ENSDART00000033103
GATA zinc finger domain containing 2Ab
chr2_-_9527129 2.30 ENSDART00000157422
ENSDART00000004398
coatomer protein complex, subunit epsilon
chr2_-_25143373 2.30 ENSDART00000160108
neutral cholesterol ester hydrolase 1a
chr18_-_7448047 2.29 ENSDART00000193213
ENSDART00000131940
ENSDART00000186944
ENSDART00000052803
si:dkey-30c15.10
chr22_-_15587360 2.28 ENSDART00000142717
ENSDART00000138978
tropomyosin 4a
chr4_-_48636872 2.28 ENSDART00000168605
zinc finger protein 1063
chr22_-_3299355 2.21 ENSDART00000190993
si:zfos-943e10.1
chr3_-_26806032 2.21 ENSDART00000143710
phosphatidylinositol glycan anchor biosynthesis, class Q
chr9_-_3400727 2.16 ENSDART00000183979
ENSDART00000111386
distal-less homeobox 2a
chr12_+_27156943 2.15 ENSDART00000153030
ENSDART00000001737
src kinase associated phosphoprotein 1
chr1_+_51475094 2.14 ENSDART00000146352
Meis homeobox 1 a
chr14_+_6535426 2.14 ENSDART00000055961
tRNA-histidine guanylyltransferase 1-like
chr21_-_40049642 2.13 ENSDART00000124416
mediator complex subunit 31
chr8_-_52715911 2.12 ENSDART00000168241
tubulin, beta 2b
chr5_+_30741730 2.11 ENSDART00000098246
ENSDART00000186992
ENSDART00000182533
finTRIM family, member 83
chr10_+_44692272 2.11 ENSDART00000157458
ubiquitin C
chr9_-_45602978 2.11 ENSDART00000139019
ENSDART00000085763
anterior gradient 1
chr11_+_3246059 2.11 ENSDART00000161529
timeless circadian clock
chr5_+_43807003 2.10 ENSDART00000097625
zgc:158640
chr2_+_53720028 2.10 ENSDART00000170799
catenin, beta like 1
chr13_-_12006007 2.10 ENSDART00000111438
meningioma expressed antigen 5 (hyaluronidase)
chr9_-_10068004 2.09 ENSDART00000011922
ENSDART00000162818
speckle-type POZ protein-like a
chr9_+_21260314 2.09 ENSDART00000145943
spindle and kinetochore associated complex subunit 3
chr17_-_43677471 2.08 ENSDART00000137015
early growth response 2a
chr19_-_42588510 2.08 ENSDART00000102583
synaptotagmin-like 1
chr3_-_29977495 2.07 ENSDART00000077111
hydroxysteroid (17-beta) dehydrogenase 14
chr14_+_52481288 2.05 ENSDART00000169164
ENSDART00000159297
transcription elongation regulator 1a (CA150)
chr14_-_31862657 2.05 ENSDART00000172870
ENSDART00000007927
ENSDART00000134748
ENSDART00000128730
RNA binding motif protein, X-linked
chr6_-_27108844 2.04 ENSDART00000073883
deoxythymidylate kinase (thymidylate kinase)
chr21_-_36396334 2.04 ENSDART00000183627
mitochondrial ribosomal protein L22
chr16_+_33938227 2.02 ENSDART00000166254
GPN-loop GTPase 2
chr13_-_40411908 2.02 ENSDART00000057094
ENSDART00000150091
NK2 homeobox 3
chr13_-_15928934 2.01 ENSDART00000142732
tubulin tyrosine ligase
chr14_+_9421510 1.98 ENSDART00000123652
high mobility group nucleosome binding domain 6
chr21_-_37973081 1.97 ENSDART00000136569
ripply transcriptional repressor 1
chr16_-_27224000 1.96 ENSDART00000126347
asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase)
chr2_-_47620806 1.96 ENSDART00000038228
adaptor-related protein complex 1, sigma 3 subunit, b
chr6_-_28943056 1.96 ENSDART00000065138
TBC1 domain family, member 23
chr6_+_149405 1.95 ENSDART00000161154
ferredoxin 1-like
chr20_-_22193190 1.95 ENSDART00000047624
transmembrane protein 165
chr23_-_25779995 1.93 ENSDART00000110670
si:dkey-21c19.3
chr21_-_13149453 1.92 ENSDART00000172578
si:dkey-228b2.6
chr5_-_28041715 1.91 ENSDART00000078660
zgc:113436
chr18_+_5308392 1.90 ENSDART00000179072
deoxyuridine triphosphatase
chr8_-_3312384 1.88 ENSDART00000035965
fucosyltransferase 9b
chr4_+_53976731 1.87 ENSDART00000165813
si:ch211-249c2.1
chr3_+_32341917 1.87 ENSDART00000055299
prolactin
chr7_+_19835569 1.87 ENSDART00000149812
ovo-like zinc finger 1a
chr20_-_36416922 1.86 ENSDART00000019145
lamin B receptor
chr21_-_13668358 1.86 ENSDART00000180323
patatin-like phospholipase domain containing 7a
chr11_+_44579865 1.85 ENSDART00000173425
nidogen 1b
chr3_-_26204867 1.85 ENSDART00000103748
glycerophosphodiester phosphodiesterase domain containing 3a
chr6_+_23810529 1.85 ENSDART00000166921
glutamate-ammonia ligase (glutamine synthase) b
chr18_-_40773413 1.84 ENSDART00000133797
vasodilator stimulated phosphoprotein b
chr8_-_28349859 1.84 ENSDART00000062671
tubulin, alpha 8 like
chr13_+_31321297 1.83 ENSDART00000143308
anthrax toxin receptor 1d
chr7_+_24205034 1.83 ENSDART00000018580
neural precursor cell expressed, developmentally down-regulated 8
chr12_-_7607114 1.83 ENSDART00000158095
solute carrier family 16, member 9b
chr9_-_41088279 1.81 ENSDART00000000564
asparagine synthetase domain containing 1
chr10_-_1523253 1.80 ENSDART00000179510
ENSDART00000176548
ENSDART00000180368
ENSDART00000185270
WD repeat domain 70
chr9_-_28255029 1.80 ENSDART00000160387
cyclin Y-like 1
chr22_-_17499513 1.80 ENSDART00000105460
si:ch211-197g15.6
chr24_+_38671054 1.79 ENSDART00000154214
si:ch73-70c5.1
chr2_-_42035250 1.77 ENSDART00000056460
ENSDART00000140788
guanylate binding protein 1
chr5_+_15203421 1.76 ENSDART00000040826
T-box 1
chr10_+_36662640 1.74 ENSDART00000063359
uncoupling protein 2
chr3_-_7524363 1.74 ENSDART00000162970
zinc finger protein 1001
chr14_-_41467497 1.73 ENSDART00000181220
MID1 interacting protein 1, like
chr21_+_34088377 1.72 ENSDART00000170070
myotubularin related protein 1b
chr4_-_35989745 1.71 ENSDART00000162568
zinc finger protein 1125
chr25_+_7532627 1.69 ENSDART00000187660
phosphatidylserine synthase 2
chr1_-_38195012 1.69 ENSDART00000020409
heart and neural crest derivatives expressed 2
chr4_-_50434519 1.69 ENSDART00000150372
zinc finger protein 1061
chr22_+_22021936 1.69 ENSDART00000149586
guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 1
chr10_+_39084354 1.67 ENSDART00000158245
si:ch73-1a9.3
chr2_+_327081 1.65 ENSDART00000155595
zgc:174263
chr3_-_36846496 1.63 ENSDART00000055237
receptor (G protein-coupled) activity modifying protein 2
chr3_-_38783951 1.63 ENSDART00000155518
zinc finger protein 281a
chr19_+_9091673 1.63 ENSDART00000052898
si:ch211-81a5.5
chr4_-_64141714 1.60 ENSDART00000128628

chr2_-_30611389 1.59 ENSDART00000142500
catenin (cadherin-associated protein), delta 2b
chr15_+_46329149 1.58 ENSDART00000128404
si:ch1073-340i21.3
chr6_+_13506841 1.57 ENSDART00000032331
GDP-mannose pyrophosphorylase Ab
chr21_-_32467799 1.57 ENSDART00000007675
ENSDART00000133099
zgc:123105
chr16_+_17252487 1.57 ENSDART00000063572
general transcription factor IIIC, polypeptide 6, alpha
chr9_-_28939796 1.55 ENSDART00000101269
erythrocyte membrane protein band 4.1 like 5
chr5_-_46329880 1.54 ENSDART00000156577
si:ch211-130m23.5
chr4_-_27129697 1.52 ENSDART00000131240
zinc finger, BED-type containing 4
chr21_-_30031396 1.51 ENSDART00000157167
PWWP domain containing 2A
chr7_-_34256374 1.50 ENSDART00000075176
DIS3 like exosome 3'-5' exoribonuclease
chr25_-_34670413 1.50 ENSDART00000073440
DnaJ heat shock protein family (Hsp40) member A4
chr24_-_9979342 1.50 ENSDART00000138576
ENSDART00000191206
zgc:171977
chr1_-_46706639 1.49 ENSDART00000074519
karyopherin alpha 3 (importin alpha 4)
chr24_+_20536056 1.48 ENSDART00000082082
glycyl-tRNA synthetase
chr9_-_10778615 1.48 ENSDART00000182577

chr7_+_48806420 1.47 ENSDART00000083431
carnitine palmitoyltransferase 1Aa (liver)
chr11_-_309420 1.46 ENSDART00000173185
POC1 centriolar protein A
chr20_-_14012859 1.45 ENSDART00000152429
si:ch211-22i13.2
chr21_-_32467099 1.44 ENSDART00000186354
zgc:123105
chr22_-_21176269 1.42 ENSDART00000112839
required for excision 1-B domain containing
chr15_-_34866219 1.42 ENSDART00000099723
SH3-binding domain protein 5-like, a
chr6_+_37625787 1.39 ENSDART00000065122
tubulin, gamma complex associated protein 5
chr6_+_52931841 1.39 ENSDART00000174358
si:dkeyp-3f10.12
chr14_-_45558490 1.38 ENSDART00000165060
integrator complex subunit 5
chr4_+_42078825 1.38 ENSDART00000164496
zinc finger protein 1060
chr22_-_34979139 1.38 ENSDART00000116455
ENSDART00000133537
Rho GTPase activating protein 19
chr24_+_37825634 1.36 ENSDART00000129889
intraflagellar transport 140 homolog (Chlamydomonas)
chr13_+_33268657 1.35 ENSDART00000002095
transmembrane protein 39B
chr25_+_30196039 1.35 ENSDART00000005299
hydroxysteroid (17-beta) dehydrogenase 12a
chr3_-_32590164 1.35 ENSDART00000151151
tetraspanin 4b
chr8_-_28274552 1.34 ENSDART00000131580
RAP1A, member of RAS oncogene family a
chr7_-_40656148 1.33 ENSDART00000142315
nucleolar protein with MIF4G domain 1
chr13_-_36798204 1.33 ENSDART00000012357
salvador family WW domain containing protein 1
chr22_-_14161309 1.33 ENSDART00000133365
si:ch211-246m6.5
chr2_+_47906240 1.33 ENSDART00000122206
finTRIM family, member 23
chr21_-_32082130 1.32 ENSDART00000003978
ENSDART00000182050
methionine adenosyltransferase II, beta
chr21_-_32081552 1.32 ENSDART00000135659
methionine adenosyltransferase II, beta
chr4_-_193762 1.31 ENSDART00000169667
protein tyrosine phosphatase, receptor type, O
chr20_+_26916639 1.31 ENSDART00000077787
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 2
chr5_+_31779911 1.29 ENSDART00000098163
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25b

Network of associatons between targets according to the STRING database.

First level regulatory network of tfcp2+tfcp2l1+ubp1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.6 GO:0000741 karyogamy(GO:0000741) pronuclear fusion(GO:0007344)
1.1 3.3 GO:0071831 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
1.1 3.2 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
1.0 3.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.8 7.4 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011)
0.8 2.4 GO:0030186 melatonin metabolic process(GO:0030186)
0.8 7.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.7 5.7 GO:0021550 medulla oblongata development(GO:0021550) dorsal motor nucleus of vagus nerve development(GO:0021744)
0.7 2.7 GO:0061033 lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.7 2.0 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.7 2.0 GO:1990403 embryonic brain development(GO:1990403)
0.6 1.9 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.6 1.9 GO:0015074 DNA integration(GO:0015074)
0.6 2.4 GO:1904667 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.6 1.8 GO:0003156 regulation of organ formation(GO:0003156)
0.5 4.8 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.5 7.8 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.5 1.9 GO:0070285 pigment cell development(GO:0070285)
0.5 4.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.5 1.8 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.4 4.4 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.4 2.1 GO:0043111 replication fork arrest(GO:0043111)
0.4 2.0 GO:0033119 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.4 2.4 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.4 3.8 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.4 2.7 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.4 2.6 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.4 3.4 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.4 2.2 GO:0046532 amacrine cell differentiation(GO:0035881) regulation of photoreceptor cell differentiation(GO:0046532)
0.4 1.1 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.4 1.8 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.3 2.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.3 3.0 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.3 3.0 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.3 2.3 GO:0032185 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.3 1.9 GO:0021767 mammillary body development(GO:0021767)
0.3 3.1 GO:0046037 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.3 2.6 GO:2001240 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.3 1.7 GO:0030859 polarized epithelial cell differentiation(GO:0030859) determination of intestine left/right asymmetry(GO:0071908)
0.3 7.3 GO:0001757 somite specification(GO:0001757)
0.3 1.3 GO:0071320 negative regulation of neurotransmitter secretion(GO:0046929) response to cAMP(GO:0051591) cellular response to cAMP(GO:0071320) negative regulation of synaptic vesicle transport(GO:1902804) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.3 1.8 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.3 1.6 GO:0019673 GDP-mannose biosynthetic process(GO:0009298) GDP-mannose metabolic process(GO:0019673)
0.2 1.0 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.2 0.7 GO:0060958 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) endocardial cell development(GO:0060958) cell proliferation involved in heart valve development(GO:2000793)
0.2 2.4 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.2 0.9 GO:0070987 error-free translesion synthesis(GO:0070987)
0.2 7.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.2 1.7 GO:1990845 adaptive thermogenesis(GO:1990845)
0.2 2.4 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.2 1.8 GO:1901998 toxin transport(GO:1901998)
0.2 3.0 GO:0045116 protein neddylation(GO:0045116)
0.2 0.8 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.2 1.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.2 0.9 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.2 2.2 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.2 1.7 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.2 0.5 GO:0030237 female sex determination(GO:0030237)
0.2 1.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 1.5 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.1 0.9 GO:0001955 blood vessel maturation(GO:0001955)
0.1 2.1 GO:0031397 negative regulation of protein ubiquitination(GO:0031397) negative regulation of protein modification by small protein conjugation or removal(GO:1903321)
0.1 0.9 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 2.6 GO:0060021 palate development(GO:0060021)
0.1 1.5 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1 0.9 GO:1901224 positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.1 1.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.4 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.1 1.4 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 0.9 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.1 1.9 GO:0016926 protein desumoylation(GO:0016926)
0.1 1.0 GO:0021794 thalamus development(GO:0021794)
0.1 2.8 GO:0007520 myoblast fusion(GO:0007520)
0.1 3.2 GO:0090148 membrane fission(GO:0090148)
0.1 1.9 GO:0033555 multicellular organismal response to stress(GO:0033555)
0.1 1.3 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 0.9 GO:0042987 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.1 0.3 GO:0045649 regulation of macrophage differentiation(GO:0045649)
0.1 0.6 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 0.7 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.1 3.8 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 1.0 GO:0014028 notochord formation(GO:0014028)
0.1 1.0 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.5 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 2.9 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.1 2.5 GO:0006695 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.1 1.9 GO:0007020 microtubule nucleation(GO:0007020)
0.1 0.5 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 2.3 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 0.7 GO:0060386 synapse assembly involved in innervation(GO:0060386)
0.1 1.2 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.1 1.8 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 1.0 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 1.2 GO:0036065 fucosylation(GO:0036065)
0.1 2.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 2.2 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 0.1 GO:0034372 triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372) reverse cholesterol transport(GO:0043691)
0.1 0.4 GO:0034505 tooth mineralization(GO:0034505)
0.1 2.3 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 1.4 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 1.4 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 0.7 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.1 0.7 GO:0051122 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 18.0 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.1 1.6 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.1 1.6 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.4 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.1 1.5 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 3.5 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.1 2.8 GO:0030217 T cell differentiation(GO:0030217)
0.0 0.2 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.0 0.8 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.4 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176) positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.0 1.4 GO:0046890 regulation of lipid biosynthetic process(GO:0046890)
0.0 0.6 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862) SMAD protein signal transduction(GO:0060395)
0.0 1.6 GO:0031623 receptor internalization(GO:0031623)
0.0 0.7 GO:0032418 lysosome localization(GO:0032418)
0.0 2.1 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 4.4 GO:0001756 somitogenesis(GO:0001756)
0.0 2.1 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 1.3 GO:0021587 cerebellum morphogenesis(GO:0021587)
0.0 2.0 GO:0042255 ribosome assembly(GO:0042255)
0.0 3.3 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 2.6 GO:0051225 spindle assembly(GO:0051225)
0.0 0.2 GO:0038066 p38MAPK cascade(GO:0038066) regulation of p38MAPK cascade(GO:1900744)
0.0 1.3 GO:0060972 left/right pattern formation(GO:0060972)
0.0 1.6 GO:0032456 endocytic recycling(GO:0032456)
0.0 2.7 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.7 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 5.7 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 2.3 GO:0007030 Golgi organization(GO:0007030)
0.0 1.2 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 1.3 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.0 2.4 GO:0009913 epidermal cell differentiation(GO:0009913)
0.0 2.1 GO:0006400 tRNA modification(GO:0006400)
0.0 1.5 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 2.1 GO:0031101 fin regeneration(GO:0031101)
0.0 0.2 GO:0031204 posttranslational protein targeting to membrane(GO:0006620) posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.2 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.0 2.9 GO:0071773 BMP signaling pathway(GO:0030509) response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
0.0 0.7 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 1.8 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.6 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.4 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 1.8 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.0 0.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.7 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.8 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.8 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.8 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.4 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 10.3 GO:0045184 establishment of protein localization(GO:0045184)
0.0 3.2 GO:0000377 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.2 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
1.0 3.1 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.8 3.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.7 13.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.7 2.6 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.6 3.8 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.6 6.8 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.5 3.3 GO:0071818 BAT3 complex(GO:0071818)
0.4 2.1 GO:0031298 replication fork protection complex(GO:0031298)
0.4 7.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.4 2.0 GO:0071203 WASH complex(GO:0071203)
0.4 2.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.3 1.4 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.3 2.0 GO:0070062 extracellular exosome(GO:0070062)
0.3 2.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.3 0.9 GO:0097361 CIA complex(GO:0097361)
0.3 2.1 GO:0070847 core mediator complex(GO:0070847)
0.3 2.4 GO:0072487 MSL complex(GO:0072487)
0.3 2.6 GO:0070652 HAUS complex(GO:0070652)
0.3 0.9 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.3 1.6 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.2 2.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.2 3.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.2 1.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.2 0.5 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.2 1.2 GO:1990130 Iml1 complex(GO:1990130)
0.1 2.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 1.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.5 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 2.0 GO:0030990 intraciliary transport particle(GO:0030990)
0.1 2.9 GO:0000145 exocyst(GO:0000145)
0.1 0.5 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 3.7 GO:0030175 filopodium(GO:0030175)
0.1 7.0 GO:0031965 nuclear membrane(GO:0031965)
0.1 3.1 GO:0032587 ruffle membrane(GO:0032587)
0.1 1.4 GO:0032039 integrator complex(GO:0032039)
0.1 2.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 2.9 GO:0031941 filamentous actin(GO:0031941)
0.1 0.6 GO:0070449 elongin complex(GO:0070449)
0.1 0.4 GO:0036156 inner dynein arm(GO:0036156)
0.1 1.0 GO:0042555 MCM complex(GO:0042555)
0.1 2.6 GO:0016592 mediator complex(GO:0016592)
0.1 0.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 6.8 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.0 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 15.3 GO:0000785 chromatin(GO:0000785)
0.0 13.6 GO:0005764 lysosome(GO:0005764)
0.0 2.4 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 2.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.0 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.8 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 1.3 GO:0035861 site of double-strand break(GO:0035861)
0.0 3.2 GO:0016607 nuclear speck(GO:0016607)
0.0 2.3 GO:0005884 actin filament(GO:0005884)
0.0 5.4 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.2 GO:0005784 Sec61 translocon complex(GO:0005784)
0.0 0.8 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 1.8 GO:0048475 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0 1.0 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 3.2 GO:0005840 ribosome(GO:0005840)
0.0 0.4 GO:0071565 nBAF complex(GO:0071565)
0.0 1.6 GO:0031968 mitochondrial outer membrane(GO:0005741) outer membrane(GO:0019867) organelle outer membrane(GO:0031968)
0.0 0.8 GO:0016342 catenin complex(GO:0016342)
0.0 2.5 GO:0005938 cell cortex(GO:0005938)
0.0 4.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.9 GO:0005930 axoneme(GO:0005930)
0.0 3.3 GO:0019866 mitochondrial inner membrane(GO:0005743) organelle inner membrane(GO:0019866)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.5 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
1.1 4.4 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
1.1 3.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.8 7.1 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.7 2.0 GO:0009041 uridylate kinase activity(GO:0009041)
0.7 14.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.6 3.7 GO:0070568 guanylyltransferase activity(GO:0070568)
0.6 7.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.5 3.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.5 1.8 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.4 2.7 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.4 1.7 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.4 3.0 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.4 4.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.4 2.7 GO:0034057 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.3 1.9 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.3 2.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.3 3.6 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.3 0.9 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.3 1.8 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 3.9 GO:0031386 protein tag(GO:0031386)
0.2 1.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.2 4.6 GO:0015026 coreceptor activity(GO:0015026)
0.2 0.9 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.2 0.7 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.2 1.5 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.2 1.0 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.2 4.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.2 1.7 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 1.7 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.2 1.8 GO:0005522 profilin binding(GO:0005522)
0.2 1.4 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1 2.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 2.9 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 3.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 1.4 GO:0002020 protease binding(GO:0002020)
0.1 3.3 GO:0051787 misfolded protein binding(GO:0051787)
0.1 2.2 GO:0004860 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.1 1.9 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 1.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.8 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 1.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 6.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.7 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.1 1.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 0.5 GO:0005549 olfactory receptor activity(GO:0004984) odorant binding(GO:0005549)
0.1 2.4 GO:0008171 O-methyltransferase activity(GO:0008171)
0.1 1.5 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487) nuclear import signal receptor activity(GO:0061608)
0.1 0.6 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 2.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 1.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.5 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 1.9 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 1.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 0.9 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 2.0 GO:0017069 snRNA binding(GO:0017069)
0.1 2.1 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 1.0 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 1.2 GO:0097602 cullin family protein binding(GO:0097602)
0.1 1.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 2.2 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 1.2 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.4 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.3 GO:0046625 sphingolipid binding(GO:0046625) ceramide binding(GO:0097001)
0.0 0.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 2.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.6 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 1.9 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 6.0 GO:0004518 nuclease activity(GO:0004518)
0.0 2.1 GO:0031625 ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.0 4.2 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 5.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 10.4 GO:0003924 GTPase activity(GO:0003924)
0.0 14.4 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 2.4 GO:0045296 cadherin binding(GO:0045296)
0.0 2.4 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 4.6 GO:0005525 GTP binding(GO:0005525)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.1 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 1.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 3.9 GO:0003682 chromatin binding(GO:0003682)
0.0 0.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 8.1 GO:0004175 endopeptidase activity(GO:0004175)
0.0 0.8 GO:0004601 peroxidase activity(GO:0004601)
0.0 31.3 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 2.9 GO:0005506 iron ion binding(GO:0005506)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 1.7 GO:0005179 hormone activity(GO:0005179)
0.0 3.4 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 11.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 2.1 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 5.5 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.1 4.1 PID P53 REGULATION PATHWAY p53 pathway
0.1 2.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 1.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 1.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 2.0 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 1.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.9 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 2.4 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.0 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 3.0 PID E2F PATHWAY E2F transcription factor network
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.0 PID ATR PATHWAY ATR signaling pathway
0.0 0.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.9 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.4 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.6 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.7 PID P73PATHWAY p73 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 6.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.5 2.6 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.5 7.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.3 4.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 5.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 2.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.2 7.2 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.2 2.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.2 6.8 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 2.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 2.1 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 2.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 3.0 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 2.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.9 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 1.0 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 1.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 1.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 1.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.8 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 1.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 3.3 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.1 3.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 5.3 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 2.8 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 1.0 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 2.4 REACTOME TRAF6 MEDIATED INDUCTION OF NFKB AND MAP KINASES UPON TLR7 8 OR 9 ACTIVATION Genes involved in TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
0.0 1.7 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.1 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases