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PRJEB1986: zebrafish developmental stages transcriptome

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Results for sp1

Z-value: 2.01

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Transcription factors associated with sp1

Gene Symbol Gene ID Gene Info
ENSDARG00000088347 sp1 transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sp1dr11_v1_chr11_-_28747_287470.752.1e-04Click!

Activity profile of sp1 motif

Sorted Z-values of sp1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_46201008 8.62 ENSDART00000160110
transglutaminase 1 like 4
chr1_-_59571758 4.91 ENSDART00000193546
ENSDART00000167087
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
chr10_-_1625080 4.03 ENSDART00000137285
nucleoporin 155
chr7_+_7630409 3.89 ENSDART00000172934
chloride channel 3
chr6_+_27991943 3.65 ENSDART00000143974
ENSDART00000141354
ENSDART00000088914
ENSDART00000139367
angiomotin like 2a
chr21_-_308852 3.37 ENSDART00000151613
LHFPL tetraspan subfamily member 2a
chr24_+_17005647 3.07 ENSDART00000149149
zinc finger protein, X-linked
chr6_+_39370587 2.99 ENSDART00000157165
ENSDART00000155079
si:dkey-195m11.8
chr24_-_37955993 2.93 ENSDART00000041805
meteorin, glial cell differentiation regulator
chr8_-_20138054 2.92 ENSDART00000133141
ENSDART00000147634
ENSDART00000029939
regulatory factor X, 2 (influences HLA class II expression)
chr3_+_1211242 2.87 ENSDART00000171287
ENSDART00000165769
polymerase (DNA-directed), delta interacting protein 3
chr16_+_46294337 2.85 ENSDART00000040769
nuclear receptor subfamily 2, group F, member 5
chr12_-_43664682 2.83 ENSDART00000159423
forkhead box i1
chr9_+_15890558 2.80 ENSDART00000144032
si:dkey-14o1.20
chr1_-_51157454 2.76 ENSDART00000047851
jagged 1a
chr25_+_16356083 2.68 ENSDART00000125925
ENSDART00000125444
TEA domain family member 1a
chr16_-_7793457 2.67 ENSDART00000113483
tripartite motif containing 71, E3 ubiquitin protein ligase
chr16_-_7443388 2.65 ENSDART00000017445
PR domain containing 1a, with ZNF domain
chr1_-_59232267 2.65 ENSDART00000169658
ENSDART00000163257
A kinase (PRKA) anchor protein 8-like
chr5_-_66028371 2.61 ENSDART00000183012
NOTCH regulated ankyrin repeat protein b
chr24_-_41180149 2.52 ENSDART00000019975
activin A receptor type 2Ba
chr3_+_41917499 2.51 ENSDART00000028673
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr18_-_49318823 2.50 ENSDART00000098419
sb:cb81
chr2_-_48826707 2.46 ENSDART00000134711
supervillin b
chr9_-_46415847 2.43 ENSDART00000009790
connexin 43.4
chr5_+_43870389 2.42 ENSDART00000141002
zgc:112966
chr20_+_33294428 2.41 ENSDART00000024104
MYCN proto-oncogene, bHLH transcription factor
chr7_-_16598212 2.41 ENSDART00000128488
E2F transcription factor 8
chr15_+_1397811 2.37 ENSDART00000102125
schwannomin interacting protein 1
chr1_-_51157660 2.27 ENSDART00000137172
jagged 1a
chr20_+_39250673 2.26 ENSDART00000153003
RALBP1 associated Eps domain containing 1
chr3_-_53559408 2.22 ENSDART00000073930
notch 3
chr22_-_34979139 2.20 ENSDART00000116455
ENSDART00000133537
Rho GTPase activating protein 19
chr23_-_3759345 2.18 ENSDART00000132205
ENSDART00000137707
ENSDART00000189382
high mobility group AT-hook 1a
chr25_-_36492779 2.17 ENSDART00000042271
iroquois homeobox 3b
chr23_-_3759692 2.13 ENSDART00000028885
high mobility group AT-hook 1a
chr22_+_465269 2.11 ENSDART00000145767
cadherin, EGF LAG seven-pass G-type receptor 2
chr22_-_26524596 2.09 ENSDART00000087623
zgc:194330
chr17_-_114121 2.07 ENSDART00000172408
ENSDART00000157784
Rho GTPase activating protein 11A
chr13_-_33822550 2.06 ENSDART00000143703
fibronectin leucine rich transmembrane 3
chr1_+_57371447 2.04 ENSDART00000152229
ENSDART00000181077
si:dkey-27j5.3
chr13_+_11439486 2.03 ENSDART00000138312
zinc finger and BTB domain containing 18
chr1_-_54107321 2.01 ENSDART00000148382
ENSDART00000150357
regulatory factor X, 1b (influences HLA class II expression)
chr5_-_66028714 1.98 ENSDART00000022625
ENSDART00000164228
NOTCH regulated ankyrin repeat protein b
chr7_-_24995631 1.98 ENSDART00000173955
ENSDART00000173791
REST corepressor 2
chr7_-_61683417 1.96 ENSDART00000098622
ENSDART00000184088
ENSDART00000148270
leucine-rich repeats and calponin homology (CH) domain containing 4
chr6_-_39313027 1.96 ENSDART00000012644
keratin 4
chr2_+_58841181 1.96 ENSDART00000164102
cold inducible RNA binding protein a
chr8_-_2591654 1.94 ENSDART00000049109
SET nuclear proto-oncogene a
chr7_+_34688527 1.93 ENSDART00000108473
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr7_+_74141297 1.92 ENSDART00000164992
RNA binding protein with multiple splicing
chr2_+_24374669 1.91 ENSDART00000133818
nuclear receptor subfamily 2, group F, member 6a
chr5_-_12219572 1.90 ENSDART00000167834
nitric oxide synthase 1 (neuronal)
chr5_+_25765522 1.89 ENSDART00000133217
transmembrane protein 2
chr5_+_25760112 1.88 ENSDART00000088011
ENSDART00000182046
transmembrane protein 2
chr18_-_127558 1.88 ENSDART00000149556
transient receptor potential cation channel, subfamily M, member 7
chr3_-_53559581 1.88 ENSDART00000183499
notch 3
chr3_+_15805917 1.85 ENSDART00000055834
phosphatase, orphan 1
chr2_+_26655744 1.85 ENSDART00000174928
aspartate beta-hydroxylase
chr8_-_53490376 1.83 ENSDART00000158789
choline dehydrogenase
chr7_+_49715750 1.83 ENSDART00000019446
achaete-scute family bHLH transcription factor 1b
chr20_+_2731436 1.81 ENSDART00000058779
ENSDART00000129870
ENSDART00000132186
ENSDART00000152727
synaptotagmin binding, cytoplasmic RNA interacting protein
chr5_-_8171625 1.81 ENSDART00000167643
solute carrier family 1 (glial high affinity glutamate transporter), member 3a
chr5_-_4532516 1.80 ENSDART00000192398
cystatin 14b, tandem duplicate 1
chr5_-_54714789 1.80 ENSDART00000063357
cyclin B1
chr20_+_30797329 1.80 ENSDART00000145066
NHS-like 1b
chr19_-_2029777 1.79 ENSDART00000128639

chr21_+_249970 1.79 ENSDART00000169026
Janus kinase 2a
chr6_+_12922002 1.76 ENSDART00000080350
ENSDART00000149018
chemokine (C-X-C motif) receptor 4a
chr10_-_31563049 1.72 ENSDART00000023575
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr18_-_46010 1.72 ENSDART00000052641
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr8_-_30979494 1.71 ENSDART00000138959
si:ch211-251j10.3
chr18_-_127873 1.71 ENSDART00000148490
transient receptor potential cation channel, subfamily M, member 7
chr6_-_45905746 1.71 ENSDART00000025428
eph receptor A2 a
chr22_+_13886821 1.70 ENSDART00000130585
ENSDART00000105711
SH3-domain binding protein 4a
chr8_+_2656681 1.70 ENSDART00000185067
ENSDART00000165943
family with sequence similarity 102, member Aa
chr1_+_29858032 1.70 ENSDART00000054066
zic family member 2 (odd-paired homolog, Drosophila) b
chr11_+_31324335 1.69 ENSDART00000088093
signal-induced proliferation-associated 1 like 2
chr2_-_39675829 1.68 ENSDART00000147821
splA/ryanodine receptor domain and SOCS box containing 4a
chr23_-_2513300 1.68 ENSDART00000067652
snail family zinc finger 1b
chr3_-_62527675 1.67 ENSDART00000155048
ENSDART00000064500
SRY (sex determining region Y)-box 9b
chr24_-_21258945 1.67 ENSDART00000111025
BOC cell adhesion associated, oncogene regulated
chr3_+_12554801 1.66 ENSDART00000167177
cyclin F
chr8_-_51753604 1.66 ENSDART00000007090
T-box 16
chr25_+_3294150 1.65 ENSDART00000030683
thymopoietin b
chr12_-_37449396 1.64 ENSDART00000152951
CDC42 effector protein (Rho GTPase binding) 4b
chr20_-_16156419 1.63 ENSDART00000037420
Ral GEF with PH domain and SH3 binding motif 2
chr9_+_34350025 1.63 ENSDART00000183451
POU class 2 homeobox 1b
chr6_-_27891961 1.61 ENSDART00000155116
im:7152348
chr7_-_52498175 1.60 ENSDART00000129769
cingulin-like 1
chr25_-_37331513 1.59 ENSDART00000111862
low density lipoprotein receptor class A domain containing 3
chr3_-_5964557 1.59 ENSDART00000184738

chr20_+_48803248 1.59 ENSDART00000164006
NK2 homeobox 4b
chr5_-_44496805 1.59 ENSDART00000110076
growth arrest-specific 1a
chr5_-_14326959 1.59 ENSDART00000137355
tet methylcytosine dioxygenase 3
chr16_-_52733384 1.57 ENSDART00000147236
ENSDART00000056101
antizyme inhibitor 1a
chr1_-_23595779 1.56 ENSDART00000134860
ENSDART00000138852
ligand dependent nuclear receptor corepressor-like
chr21_-_11646878 1.56 ENSDART00000162426
ENSDART00000135937
ENSDART00000131448
ENSDART00000148097
ENSDART00000133443
calpastatin
chr12_-_26851726 1.54 ENSDART00000047724
zinc finger E-box binding homeobox 1b
chr7_-_5396154 1.54 ENSDART00000172980
Rho guanine nucleotide exchange factor (GEF) 11
chr5_+_72152813 1.51 ENSDART00000149910
c-abl oncogene 1, non-receptor tyrosine kinase
chr3_-_21094437 1.50 ENSDART00000153739
ENSDART00000109790
nemo-like kinase, type 1
chr19_-_15855427 1.49 ENSDART00000133059
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4a
chr13_+_15941850 1.49 ENSDART00000016294
fidgetin-like 1
chr4_-_56703300 1.47 ENSDART00000160063
zinc finger protein 1118
chr2_+_24376373 1.47 ENSDART00000135323
nuclear receptor subfamily 2, group F, member 6a
chr17_-_10059557 1.47 ENSDART00000092209
ENSDART00000161243
bromodomain adjacent to zinc finger domain, 1A
chr10_+_10210455 1.47 ENSDART00000144214
SH2 domain containing 3Ca
chr20_-_28698172 1.46 ENSDART00000190635
signal-induced proliferation-associated 1 like 1
chr3_+_46559639 1.46 ENSDART00000146189
ENSDART00000127832
ENSDART00000151035
ribonucleoprotein, PTB-binding 1
chr7_+_1579236 1.46 ENSDART00000172830
SPT16 homolog, facilitates chromatin remodeling subunit
chr13_-_40316367 1.45 ENSDART00000009343
pyridine nucleotide-disulphide oxidoreductase domain 2
chr25_-_348784 1.45 ENSDART00000059514
prickle homolog 1a
chr1_+_15062 1.44 ENSDART00000169005
centrosomal protein 97
chr11_-_19775182 1.44 ENSDART00000037894
nicotinamide phosphoribosyltransferase b
chr6_+_32326074 1.43 ENSDART00000042134
ENSDART00000181177
dedicator of cytokinesis 7
chr7_-_33114884 1.43 ENSDART00000052385
tryptophan hydroxylase 1b
chr24_+_42127983 1.43 ENSDART00000190157
ENSDART00000176032
ENSDART00000175790
WW domain containing E3 ubiquitin protein ligase 1
chr15_-_3736773 1.43 ENSDART00000090624
lysophosphatidic acid receptor 6a
chr21_-_13972745 1.40 ENSDART00000143874
AT-hook transcription factor
chr14_+_31865099 1.40 ENSDART00000189124
transmembrane 9 superfamily protein member 5
chr2_+_24374305 1.40 ENSDART00000022379
nuclear receptor subfamily 2, group F, member 6a
chr7_-_45852270 1.40 ENSDART00000170224
SHC SH2-domain binding protein 1
chr19_-_6193067 1.39 ENSDART00000092656
ENSDART00000140347
Ets2 repressor factor
chr10_-_35257458 1.39 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
proline rich 11
chr12_-_42214 1.39 ENSDART00000045071
forkhead box K2
chr20_+_710052 1.38 ENSDART00000166656
SUMO1/sentrin specific peptidase 6a
chr5_-_54714525 1.37 ENSDART00000150138
ENSDART00000150070
cyclin B1
chr4_-_5795309 1.37 ENSDART00000039987
phosphoglucomutase 3
chr10_-_641609 1.37 ENSDART00000041236
regulatory factor X, 3 (influences HLA class II expression)
chr2_+_43469241 1.37 ENSDART00000142078
ENSDART00000098265
neuropilin 1b
chr22_+_413349 1.37 ENSDART00000082453
cadherin, EGF LAG seven-pass G-type receptor 2
chr14_+_31865324 1.37 ENSDART00000039880
transmembrane 9 superfamily protein member 5
chr23_+_21380079 1.37 ENSDART00000089379
intermediate filament family orphan 2a
chr23_+_5524247 1.36 ENSDART00000189679
ENSDART00000083622
TEA domain family member 3 a
chr7_-_18881358 1.36 ENSDART00000021502
MLLT3, super elongation complex subunit
chr14_-_12822 1.36 ENSDART00000180650
ENSDART00000188819
muscle segment homeobox 1a
chr16_-_52646789 1.36 ENSDART00000035761
ubiquitin protein ligase E3 component n-recognin 5
chr17_-_28811747 1.36 ENSDART00000001444
G2/M-phase specific E3 ubiquitin protein ligase
chr19_+_42716542 1.35 ENSDART00000144557
cytoplasmic linker associated protein 2
chr18_-_50845804 1.34 ENSDART00000158517
si:cabz01113374.3
chr1_-_669717 1.34 ENSDART00000160564
cysteine/tyrosine-rich 1
chr14_-_42231293 1.34 ENSDART00000185486

chr22_+_10232527 1.33 ENSDART00000139297
si:dkeyp-87e7.4
chr15_+_19838458 1.33 ENSDART00000101204
activated leukocyte cell adhesion molecule b
chr5_+_68807170 1.33 ENSDART00000017849
hairy and enhancer of split related-7
chr1_+_14454663 1.31 ENSDART00000005067
recombination signal binding protein for immunoglobulin kappa J region a
chr4_-_23839789 1.31 ENSDART00000143571
USP6 N-terminal like
chr19_+_48060464 1.31 ENSDART00000123163
zgc:85936
chr5_-_63515210 1.30 ENSDART00000022348
PR domain containing 12b
chr21_-_37027252 1.30 ENSDART00000076483
zgc:77151
chr8_+_31016180 1.30 ENSDART00000130870
ENSDART00000143604
outer dense fiber of sperm tails 2b
chr7_-_51102479 1.30 ENSDART00000174023
collagen, type IV, alpha 6
chr24_+_17140938 1.29 ENSDART00000149134
MLLT10, histone lysine methyltransferase DOT1L cofactor
chr17_-_10059996 1.29 ENSDART00000166984
bromodomain adjacent to zinc finger domain, 1A
chr13_+_5978809 1.29 ENSDART00000102563
ENSDART00000121598
PHD finger protein 10
chr3_-_32362872 1.28 ENSDART00000035545
ENSDART00000012630
protein arginine methyltransferase 1
chr14_-_237130 1.28 ENSDART00000164988
biorientation of chromosomes in cell division 1-like 1
chr21_-_39024754 1.28 ENSDART00000056878
tnf receptor-associated factor 4b
chr3_+_23692462 1.28 ENSDART00000145934
homeobox B7a
chr8_+_4697764 1.27 ENSDART00000064197
claudin 5a
chr18_-_14677936 1.26 ENSDART00000111995
si:dkey-238o13.4
chr20_+_51061695 1.26 ENSDART00000134416
im:7140055
chr23_+_31107685 1.26 ENSDART00000103448
T-box 18
chr20_-_2584101 1.26 ENSDART00000141595
ENSDART00000135760
mediator complex subunit 23
chr5_+_35398745 1.25 ENSDART00000098010
prostaglandin E receptor 4 (subtype EP4) b
chr8_+_29962635 1.25 ENSDART00000007640
patched 1
chr20_-_25748407 1.24 ENSDART00000063152
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr16_-_53919115 1.24 ENSDART00000179533
frizzled class receptor 1
chr1_-_45584407 1.23 ENSDART00000149155
activating transcription factor 7 interacting protein
chr20_+_4157815 1.23 ENSDART00000113132
glyceronephosphate O-acyltransferase
chr2_-_44282796 1.23 ENSDART00000163040
ENSDART00000166923
ENSDART00000056372
ENSDART00000109251
ENSDART00000132682
myelin protein zero
chr11_-_30138299 1.23 ENSDART00000172106
Scm polycomb group protein like 2
chr5_+_67390645 1.23 ENSDART00000014822
early B cell factor 2
chr3_+_12322170 1.23 ENSDART00000161227
GLIS family zinc finger 2b
chr12_+_48841182 1.22 ENSDART00000109315
ENSDART00000185609
ENSDART00000187217
discs, large homolog 5b (Drosophila), tandem duplicate 1
chr7_-_64971839 1.22 ENSDART00000164682
SIN3-HDAC complex associated factor, like
chr12_+_14149686 1.22 ENSDART00000123741
kelch repeat and BTB (POZ) domain containing 2
chr23_+_44634187 1.21 ENSDART00000143688
si:ch73-265d7.2
chr7_+_22718251 1.21 ENSDART00000027718
ENSDART00000143341
fragile X mental retardation, autosomal homolog 2
chr25_+_150570 1.21 ENSDART00000170892
ADAM metallopeptidase domain 10b
chr16_+_33953644 1.21 ENSDART00000164447
ENSDART00000159969
AT rich interactive domain 1Aa (SWI-like)
chr23_-_14403939 1.20 ENSDART00000090930
sodium/potassium transporting ATPase interacting 4
chr1_-_45616470 1.20 ENSDART00000150165
activating transcription factor 7 interacting protein
chr1_-_45580787 1.19 ENSDART00000135089
activating transcription factor 7 interacting protein
chr7_+_24881680 1.19 ENSDART00000058843
kelch repeat-containing protein
chr11_-_7139555 1.19 ENSDART00000016472
bone morphogenetic protein 7a
chr17_+_25856671 1.19 ENSDART00000064817
WAPL cohesin release factor a
chr5_-_68782641 1.18 ENSDART00000141699
methylphosphate capping enzyme
chr19_+_14352332 1.17 ENSDART00000164386
AT rich interactive domain 1Ab (SWI-like)
chr25_-_6389713 1.17 ENSDART00000083539
SIN3 transcription regulator family member Aa
chr23_+_10347851 1.17 ENSDART00000127667
keratin 18
chr10_+_17713022 1.17 ENSDART00000170453
solute carrier family 20 (phosphate transporter), member 1b
chr4_-_1720648 1.16 ENSDART00000103484
growth arrest-specific 2 like 3
chr6_+_54576520 1.16 ENSDART00000093199
ENSDART00000127519
ENSDART00000157142
TEA domain family member 3 b
chr12_+_695619 1.16 ENSDART00000161691
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr17_+_51746830 1.16 ENSDART00000184230
ornithine decarboxylase 1
chr16_+_32559821 1.15 ENSDART00000093250
POU class 3 homeobox 2b
chr4_+_15006217 1.15 ENSDART00000090837
zinc finger, C3HC-type containing 1
chr18_-_16924221 1.15 ENSDART00000122102
WEE1 G2 checkpoint kinase

Network of associatons between targets according to the STRING database.

First level regulatory network of sp1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0035019 somatic stem cell population maintenance(GO:0035019) symmetric cell division(GO:0098725)
1.3 4.0 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
1.2 3.6 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
1.1 4.5 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.8 2.4 GO:0006600 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.7 0.7 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.7 2.8 GO:0048890 epidermal cell fate specification(GO:0009957) lateral line ganglion development(GO:0048890)
0.6 1.9 GO:0098924 retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by nitric oxide(GO:0098924)
0.6 1.8 GO:0019695 choline metabolic process(GO:0019695)
0.6 4.8 GO:0035912 aorta morphogenesis(GO:0035909) dorsal aorta morphogenesis(GO:0035912)
0.6 1.7 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.6 1.7 GO:0048341 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341) intermediate mesoderm development(GO:0048389)
0.5 2.7 GO:0010586 miRNA metabolic process(GO:0010586)
0.5 1.5 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.5 2.0 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.5 2.3 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.5 0.9 GO:0035477 regulation of angioblast cell migration involved in selective angioblast sprouting(GO:0035477)
0.4 1.8 GO:0021703 locus ceruleus development(GO:0021703)
0.4 1.3 GO:0072314 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.4 2.2 GO:0035777 pronephric distal tubule development(GO:0035777)
0.4 1.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.4 1.7 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.4 2.1 GO:1901166 neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.4 2.5 GO:0055016 hypochord development(GO:0055016)
0.4 1.7 GO:0061032 visceral serous pericardium development(GO:0061032)
0.4 2.1 GO:0042264 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.4 5.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.4 1.6 GO:0032208 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
0.4 1.2 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.4 1.2 GO:1904869 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.4 8.6 GO:0018149 peptide cross-linking(GO:0018149)
0.4 3.8 GO:0001709 cell fate determination(GO:0001709)
0.4 3.4 GO:0046546 development of primary male sexual characteristics(GO:0046546)
0.4 1.1 GO:0007571 age-dependent general metabolic decline(GO:0007571)
0.4 1.1 GO:0009397 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.4 1.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.4 4.7 GO:0090308 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.4 2.9 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.4 3.2 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.3 6.6 GO:0030878 thyroid gland development(GO:0030878)
0.3 1.4 GO:0090230 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.3 1.3 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.3 2.7 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.3 1.7 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.3 1.0 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.3 1.0 GO:0060571 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.3 8.4 GO:0035329 hippo signaling(GO:0035329)
0.3 1.3 GO:0034969 histone arginine methylation(GO:0034969)
0.3 0.6 GO:0021742 abducens nucleus development(GO:0021742)
0.3 1.6 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.3 1.3 GO:0042308 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.3 2.8 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.3 0.9 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.3 0.9 GO:0035676 anterior lateral line neuromast hair cell development(GO:0035676)
0.3 0.9 GO:0045887 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.3 0.9 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.3 3.5 GO:0021754 facial nucleus development(GO:0021754)
0.3 1.1 GO:1900136 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.3 0.8 GO:0043525 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.3 1.7 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.3 1.1 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.3 1.6 GO:0050655 dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.3 1.3 GO:0021885 forebrain cell migration(GO:0021885)
0.3 1.0 GO:0016103 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.3 1.3 GO:0071380 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.2 1.0 GO:0060471 negative regulation of fertilization(GO:0060467) prevention of polyspermy(GO:0060468) cortical granule exocytosis(GO:0060471)
0.2 1.0 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.2 0.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 1.0 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.2 0.7 GO:0002369 T cell cytokine production(GO:0002369)
0.2 1.7 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.2 2.2 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.2 1.8 GO:0021535 cell migration in hindbrain(GO:0021535)
0.2 1.4 GO:1900044 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.2 1.6 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.2 0.7 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.2 0.7 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.2 1.1 GO:0000012 single strand break repair(GO:0000012)
0.2 1.1 GO:0060584 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.2 0.4 GO:0072020 proximal straight tubule development(GO:0072020)
0.2 0.6 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.2 1.1 GO:0090527 actin filament reorganization(GO:0090527)
0.2 0.6 GO:0070417 cellular response to cold(GO:0070417)
0.2 2.1 GO:0031269 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.2 0.6 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.2 0.6 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.2 0.4 GO:0071867 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.2 0.6 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.2 1.4 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.2 0.6 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.2 0.8 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.2 0.6 GO:0001839 neural plate morphogenesis(GO:0001839)
0.2 2.5 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.2 3.1 GO:0060046 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.2 0.4 GO:0072025 distal convoluted tubule development(GO:0072025) late distal convoluted tubule development(GO:0072068)
0.2 0.7 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.2 0.5 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.2 1.1 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.2 0.5 GO:0001113 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.2 0.9 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.2 0.5 GO:0050748 N-terminal protein palmitoylation(GO:0006500) negative regulation of lipoprotein metabolic process(GO:0050748) regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.2 1.7 GO:0046548 retinal rod cell development(GO:0046548)
0.2 0.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.2 1.0 GO:0097638 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.2 3.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.2 1.2 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.2 2.5 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.2 1.5 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.2 1.0 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.2 0.6 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.2 1.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.2 0.8 GO:0098900 regulation of action potential(GO:0098900)
0.2 0.6 GO:0072103 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.2 1.7 GO:0071679 commissural neuron axon guidance(GO:0071679)
0.2 0.3 GO:0038179 neurotrophin signaling pathway(GO:0038179) nerve growth factor signaling pathway(GO:0038180)
0.2 0.6 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.2 0.5 GO:0005997 xylulose metabolic process(GO:0005997)
0.2 0.8 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.1 2.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.3 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.6 GO:1904182 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.1 1.0 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.7 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.1 1.8 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 0.7 GO:0071480 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.1 1.7 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.7 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 1.2 GO:0039023 pronephric duct morphogenesis(GO:0039023) nephric duct morphogenesis(GO:0072178)
0.1 1.1 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.1 1.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.4 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.1 1.1 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 1.5 GO:0021854 hypothalamus development(GO:0021854)
0.1 1.7 GO:0060729 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.1 1.4 GO:0051382 kinetochore assembly(GO:0051382)
0.1 1.1 GO:0003160 endocardium morphogenesis(GO:0003160)
0.1 0.4 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.1 0.6 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 1.2 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444)
0.1 0.3 GO:0070293 renal absorption(GO:0070293)
0.1 0.8 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.1 0.5 GO:0010610 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.1 1.3 GO:0070307 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.1 0.3 GO:0055071 manganese ion homeostasis(GO:0055071)
0.1 0.4 GO:0061033 lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.1 0.7 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 2.0 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.8 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 0.9 GO:0021627 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.1 0.6 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.1 1.0 GO:0044458 motile cilium assembly(GO:0044458)
0.1 2.1 GO:0097178 ruffle assembly(GO:0097178)
0.1 0.7 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.7 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.1 0.9 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 1.1 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 0.6 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.7 GO:0043931 ossification involved in bone maturation(GO:0043931) bone maturation(GO:0070977)
0.1 2.2 GO:0043049 otic placode formation(GO:0043049)
0.1 3.1 GO:0051014 actin filament severing(GO:0051014)
0.1 0.4 GO:0032534 regulation of microvillus organization(GO:0032530) regulation of microvillus assembly(GO:0032534)
0.1 0.2 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.1 0.6 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 0.4 GO:0090148 membrane fission(GO:0090148)
0.1 1.9 GO:0071456 cellular response to hypoxia(GO:0071456)
0.1 0.5 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.1 0.2 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.1 1.3 GO:0043268 positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 2.9 GO:0003351 epithelial cilium movement(GO:0003351)
0.1 0.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 8.1 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.1 2.7 GO:0030500 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.1 0.6 GO:0061056 sclerotome development(GO:0061056)
0.1 0.9 GO:0015813 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.1 0.5 GO:0070650 actin filament bundle distribution(GO:0070650)
0.1 0.3 GO:1904950 negative regulation of protein transport(GO:0051224) negative regulation of establishment of protein localization(GO:1904950)
0.1 2.1 GO:0007379 somite specification(GO:0001757) segment specification(GO:0007379)
0.1 0.5 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 0.8 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.1 0.9 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.1 0.3 GO:0090003 regulation of Golgi to plasma membrane protein transport(GO:0042996) positive regulation of Golgi to plasma membrane protein transport(GO:0042998) regulation of establishment of protein localization to plasma membrane(GO:0090003) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 0.4 GO:0060876 semicircular canal formation(GO:0060876)
0.1 0.7 GO:0060036 notochord cell vacuolation(GO:0060036)
0.1 0.3 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168)
0.1 0.9 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.1 0.6 GO:0043363 nucleate erythrocyte differentiation(GO:0043363)
0.1 0.5 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.1 0.6 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.1 0.7 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.1 0.3 GO:0006591 ornithine metabolic process(GO:0006591)
0.1 0.4 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 0.8 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.5 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338) negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.1 0.7 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 1.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 1.1 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.1 0.2 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.1 0.4 GO:0019370 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.1 0.6 GO:0090398 cellular senescence(GO:0090398)
0.1 0.9 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 0.1 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.1 0.1 GO:0098773 skin epidermis development(GO:0098773)
0.1 1.2 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1 0.4 GO:0034505 tooth mineralization(GO:0034505)
0.1 4.3 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.1 0.3 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.1 0.5 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.1 1.4 GO:0010458 exit from mitosis(GO:0010458)
0.1 1.7 GO:0001522 pseudouridine synthesis(GO:0001522)
0.1 2.6 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.1 3.9 GO:0016575 histone deacetylation(GO:0016575)
0.1 0.3 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.1 2.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 1.1 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 0.7 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.3 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.9 GO:1902253 regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902253) negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.1 0.4 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 1.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.4 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.1 0.3 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 1.8 GO:0046427 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.1 0.8 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 2.6 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.1 0.6 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.1 0.6 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.4 GO:0030104 water homeostasis(GO:0030104)
0.1 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.9 GO:1903672 positive regulation of sprouting angiogenesis(GO:1903672)
0.1 0.2 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.1 1.6 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 1.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.4 GO:0044319 wound healing, spreading of cells(GO:0044319) epiboly involved in wound healing(GO:0090505) skeletal muscle satellite cell migration(GO:1902766)
0.1 0.6 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 1.0 GO:0046686 response to cadmium ion(GO:0046686)
0.1 0.5 GO:0006582 melanin metabolic process(GO:0006582)
0.1 0.6 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 0.5 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.5 GO:0072160 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014) nephron tubule epithelial cell differentiation(GO:0072160)
0.1 1.4 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 1.6 GO:0048538 thymus development(GO:0048538)
0.1 2.0 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 0.6 GO:1902017 regulation of cilium assembly(GO:1902017)
0.1 0.9 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 0.4 GO:0007004 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.1 0.2 GO:0032602 chemokine production(GO:0032602) toll-like receptor 3 signaling pathway(GO:0034138)
0.1 0.5 GO:0021684 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 2.0 GO:0021575 hindbrain morphogenesis(GO:0021575)
0.1 0.5 GO:0048634 regulation of muscle organ development(GO:0048634)
0.1 0.5 GO:0034435 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.1 0.5 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.4 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.1 1.0 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 1.5 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.2 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 1.0 GO:0001966 thigmotaxis(GO:0001966)
0.0 0.6 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.1 GO:0060137 parturition(GO:0007567) multi-multicellular organism process(GO:0044706) maternal process involved in parturition(GO:0060137)
0.0 1.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0030327 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.0 0.6 GO:0060324 face development(GO:0060324)
0.0 0.1 GO:0055021 regulation of cardiac muscle tissue growth(GO:0055021) regulation of cardiac muscle cell proliferation(GO:0060043)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.8 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.9 GO:0006301 postreplication repair(GO:0006301)
0.0 0.8 GO:0014020 neural tube closure(GO:0001843) primary neural tube formation(GO:0014020) tube closure(GO:0060606)
0.0 0.2 GO:0017003 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.0 1.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.4 GO:0046850 regulation of tissue remodeling(GO:0034103) regulation of bone remodeling(GO:0046850)
0.0 4.9 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 2.1 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.0 0.3 GO:0050714 positive regulation of protein secretion(GO:0050714)
0.0 4.5 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 1.1 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.2 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.0 0.5 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.2 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.3 GO:0003232 bulbus arteriosus development(GO:0003232)
0.0 2.2 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.2 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 5.6 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.5 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.6 GO:0071897 DNA biosynthetic process(GO:0071897)
0.0 1.9 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.5 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.8 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 1.3 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.4 GO:0022011 myelination in peripheral nervous system(GO:0022011)
0.0 1.5 GO:0016331 morphogenesis of embryonic epithelium(GO:0016331)
0.0 0.3 GO:0051785 positive regulation of mitotic nuclear division(GO:0045840) positive regulation of nuclear division(GO:0051785)
0.0 0.9 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.5 GO:0060872 semicircular canal development(GO:0060872)
0.0 0.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.6 GO:0021884 forebrain neuron development(GO:0021884)
0.0 1.5 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.2 GO:0015862 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.0 0.7 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 0.8 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.0 3.6 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 2.7 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.2 GO:0046294 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.0 0.2 GO:0003272 endocardial cushion formation(GO:0003272)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 1.2 GO:0001885 endothelial cell development(GO:0001885)
0.0 1.3 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.6 GO:0051402 neuron apoptotic process(GO:0051402)
0.0 0.7 GO:0060536 cartilage morphogenesis(GO:0060536)
0.0 0.7 GO:0000723 telomere maintenance(GO:0000723) telomere organization(GO:0032200)
0.0 0.2 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.0 1.0 GO:0001935 endothelial cell proliferation(GO:0001935)
0.0 1.6 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.6 GO:0007257 activation of JUN kinase activity(GO:0007257) regulation of JUN kinase activity(GO:0043506) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.2 GO:0018904 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 2.5 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.0 1.1 GO:0051693 actin filament capping(GO:0051693)
0.0 1.2 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.4 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 1.0 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.1 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.0 0.2 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.7 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 1.7 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 0.3 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 0.8 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.1 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.5 GO:0061035 regulation of cartilage development(GO:0061035)
0.0 0.3 GO:0060972 left/right pattern formation(GO:0060972)
0.0 1.3 GO:0008360 regulation of cell shape(GO:0008360)
0.0 1.1 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.7 GO:0051028 mRNA transport(GO:0051028)
0.0 2.4 GO:0006821 chloride transport(GO:0006821)
0.0 0.4 GO:0043687 post-translational protein modification(GO:0043687)
0.0 0.0 GO:0006699 bile acid biosynthetic process(GO:0006699) bile acid metabolic process(GO:0008206)
0.0 0.1 GO:0070828 heterochromatin organization(GO:0070828)
0.0 0.6 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.2 GO:0061099 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.1 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.3 GO:0031076 embryonic camera-type eye development(GO:0031076)
0.0 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.2 GO:0045766 positive regulation of angiogenesis(GO:0045766)
0.0 0.9 GO:0044344 fibroblast growth factor receptor signaling pathway(GO:0008543) cellular response to fibroblast growth factor stimulus(GO:0044344) response to fibroblast growth factor(GO:0071774)
0.0 0.2 GO:0033628 regulation of cell adhesion mediated by integrin(GO:0033628)
0.0 0.6 GO:0003401 axis elongation(GO:0003401)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.9 GO:0007043 cell-cell junction assembly(GO:0007043)
0.0 0.8 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.7 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.0 0.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 1.1 GO:0006913 nucleocytoplasmic transport(GO:0006913) nuclear transport(GO:0051169)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 2.7 GO:1904888 cranial skeletal system development(GO:1904888)
0.0 0.5 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 0.2 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.8 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.1 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.1 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 1.2 GO:0048793 pronephros development(GO:0048793)
0.0 2.5 GO:0000377 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 3.5 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.0 0.1 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.0 0.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0030534 adult behavior(GO:0030534)
0.0 0.2 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.0 0.1 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.3 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.3 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.9 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.1 GO:0061615 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.5 GO:0031101 fin regeneration(GO:0031101)
0.0 0.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.1 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.2 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.1 GO:0030517 negative regulation of axon extension(GO:0030517) negative regulation of axonogenesis(GO:0050771)
0.0 0.3 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.2 GO:0009950 dorsal/ventral axis specification(GO:0009950)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
1.0 4.0 GO:0044611 nuclear pore inner ring(GO:0044611)
0.4 1.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.3 1.3 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.3 1.2 GO:1902737 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.3 2.4 GO:0035060 brahma complex(GO:0035060)
0.3 2.9 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.3 1.7 GO:0098651 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.3 2.8 GO:0045095 keratin filament(GO:0045095)
0.2 0.7 GO:0098536 deuterosome(GO:0098536)
0.2 3.2 GO:0048179 activin receptor complex(GO:0048179)
0.2 2.5 GO:0035101 FACT complex(GO:0035101)
0.2 0.6 GO:0032301 MutSalpha complex(GO:0032301)
0.2 0.8 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.2 2.2 GO:0071564 npBAF complex(GO:0071564)
0.2 3.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 0.6 GO:0032584 growth cone membrane(GO:0032584)
0.2 1.9 GO:0016580 Sin3 complex(GO:0016580)
0.2 0.8 GO:0008091 spectrin(GO:0008091)
0.2 1.1 GO:0071818 BAT3 complex(GO:0071818)
0.1 1.0 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 0.8 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 0.5 GO:0060171 stereocilium membrane(GO:0060171)
0.1 0.8 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 1.6 GO:0070187 telosome(GO:0070187)
0.1 1.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.5 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 2.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 0.6 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.6 GO:1990130 Iml1 complex(GO:1990130)
0.1 1.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 1.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 0.3 GO:0070578 RISC-loading complex(GO:0070578)
0.1 1.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 1.1 GO:0014704 intercalated disc(GO:0014704)
0.1 0.9 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.9 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 2.0 GO:0045180 basal cortex(GO:0045180)
0.1 0.3 GO:0097255 R2TP complex(GO:0097255)
0.1 0.4 GO:0034359 mature chylomicron(GO:0034359)
0.1 9.9 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 6.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 0.7 GO:0016272 prefoldin complex(GO:0016272)
0.1 4.6 GO:0031901 early endosome membrane(GO:0031901)
0.1 1.6 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 3.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 1.4 GO:0032039 integrator complex(GO:0032039)
0.1 0.7 GO:0032432 actin filament bundle(GO:0032432)
0.1 0.6 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.2 GO:1990879 CST complex(GO:1990879)
0.1 0.3 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.1 1.0 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.5 GO:0032019 mitochondrial cloud(GO:0032019)
0.1 1.1 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 0.8 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 1.0 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.3 GO:0016234 inclusion body(GO:0016234)
0.1 0.3 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 3.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 1.0 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.8 GO:0030057 desmosome(GO:0030057)
0.0 0.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.4 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.0 0.7 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 1.0 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.9 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.2 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.0 1.7 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.6 GO:0042555 MCM complex(GO:0042555)
0.0 1.0 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 1.2 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.7 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 1.0 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.6 GO:0015030 Cajal body(GO:0015030)
0.0 0.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 1.6 GO:0016592 mediator complex(GO:0016592)
0.0 1.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.4 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 2.6 GO:0055037 recycling endosome(GO:0055037)
0.0 3.9 GO:0016459 myosin complex(GO:0016459)
0.0 5.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.3 GO:0030904 retromer complex(GO:0030904)
0.0 2.4 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.5 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.9 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.0 0.2 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 8.2 GO:0000785 chromatin(GO:0000785)
0.0 2.9 GO:0016607 nuclear speck(GO:0016607)
0.0 0.7 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 3.1 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.9 GO:0016342 catenin complex(GO:0016342)
0.0 0.7 GO:0044447 axoneme part(GO:0044447)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 1.1 GO:0005814 centriole(GO:0005814)
0.0 1.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.9 GO:0042641 actomyosin(GO:0042641)
0.0 1.3 GO:0000922 spindle pole(GO:0000922)
0.0 0.5 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 1.9 GO:0005813 centrosome(GO:0005813)
0.0 1.3 GO:0005815 microtubule organizing center(GO:0005815)
0.0 0.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 87.7 GO:0005634 nucleus(GO:0005634)
0.0 0.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.0 GO:1990923 PET complex(GO:1990923)
0.0 0.4 GO:0030286 dynein complex(GO:0030286)
0.0 0.8 GO:0005769 early endosome(GO:0005769)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.9 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.0 GO:0016323 basolateral plasma membrane(GO:0016323)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 6.4 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.6 1.9 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.6 2.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.5 2.2 GO:0097108 hedgehog family protein binding(GO:0097108)
0.5 2.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.4 1.3 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.4 1.3 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.4 1.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.4 8.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.4 10.4 GO:0005112 Notch binding(GO:0005112)
0.4 1.1 GO:0031701 angiotensin receptor binding(GO:0031701)
0.4 1.1 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.4 4.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.4 1.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.3 1.0 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.3 3.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.3 2.8 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.3 0.9 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.3 3.1 GO:0035804 structural constituent of egg coat(GO:0035804)
0.3 1.6 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.3 1.9 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.3 2.7 GO:0035198 miRNA binding(GO:0035198)
0.3 1.0 GO:0001096 TFIIF-class transcription factor binding(GO:0001096)
0.3 5.6 GO:0005003 ephrin receptor activity(GO:0005003)
0.2 3.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.2 1.0 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2 2.7 GO:0005158 insulin receptor binding(GO:0005158)
0.2 1.6 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 1.6 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.2 3.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.2 1.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.2 0.8 GO:0070034 telomerase RNA binding(GO:0070034)
0.2 0.6 GO:0043621 protein self-association(GO:0043621)
0.2 0.6 GO:0032143 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.2 3.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 4.6 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.2 4.0 GO:0048185 activin binding(GO:0048185)
0.2 1.0 GO:0019960 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2 0.8 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.2 0.9 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.2 0.7 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.2 1.1 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 1.8 GO:0070700 BMP receptor binding(GO:0070700)
0.2 0.7 GO:0008459 chondroitin 6-sulfotransferase activity(GO:0008459)
0.2 1.4 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2 0.5 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)
0.2 1.4 GO:0043515 kinetochore binding(GO:0043515)
0.2 0.6 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 1.0 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.6 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.6 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 1.0 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 0.7 GO:0070412 R-SMAD binding(GO:0070412)
0.1 4.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.4 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.1 0.5 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 0.3 GO:0070883 pre-miRNA binding(GO:0070883)
0.1 1.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.8 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 0.9 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.8 GO:0019215 intermediate filament binding(GO:0019215)
0.1 1.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 6.4 GO:0031491 nucleosome binding(GO:0031491)
0.1 0.7 GO:0042974 estrogen receptor binding(GO:0030331) retinoic acid receptor binding(GO:0042974)
0.1 1.9 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 1.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 3.9 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.1 0.5 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 1.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.7 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.4 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 1.0 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 1.0 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.9 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.3 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 1.7 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1 0.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.7 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 0.4 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.1 1.3 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 0.7 GO:0035173 histone kinase activity(GO:0035173)
0.1 1.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.9 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.4 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.3 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 1.7 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 1.5 GO:0008013 beta-catenin binding(GO:0008013)
0.1 0.8 GO:0050700 CARD domain binding(GO:0050700)
0.1 2.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.6 GO:0030274 LIM domain binding(GO:0030274)
0.1 5.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.2 GO:0008022 protein C-terminus binding(GO:0008022)
0.1 0.4 GO:0060182 apelin receptor activity(GO:0060182)
0.1 0.9 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.6 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.6 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.6 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 0.7 GO:0005113 patched binding(GO:0005113)
0.1 0.5 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.3 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 0.4 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.6 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.7 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 1.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 1.3 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 1.5 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 0.9 GO:0030507 spectrin binding(GO:0030507)
0.1 0.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 2.2 GO:0051018 protein kinase A binding(GO:0051018)
0.1 0.5 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 1.6 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 0.3 GO:0071253 connexin binding(GO:0071253)
0.1 1.1 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 3.2 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 1.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 0.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 1.2 GO:0017069 snRNA binding(GO:0017069)
0.1 0.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 4.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 1.4 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 0.4 GO:0004630 phospholipase D activity(GO:0004630)
0.1 0.3 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.3 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.1 0.7 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.6 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1 0.9 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.3 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 8.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 0.2 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1 0.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.1 GO:0004990 oxytocin receptor activity(GO:0004990)
0.0 0.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.6 GO:0098631 protein binding involved in cell adhesion(GO:0098631)
0.0 0.2 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.8 GO:0002039 p53 binding(GO:0002039)
0.0 7.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.7 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.0 0.2 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.0 0.2 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 0.4 GO:0070325 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
0.0 1.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 1.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.2 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.0 1.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.4 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.2 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.3 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.6 GO:0031386 protein tag(GO:0031386)
0.0 3.5 GO:0045296 cadherin binding(GO:0045296)
0.0 0.9 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 11.8 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.8 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 1.4 GO:0005109 frizzled binding(GO:0005109)
0.0 6.6 GO:0000989 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 0.4 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.0 0.3 GO:0016530 metallochaperone activity(GO:0016530)
0.0 6.2 GO:0042393 histone binding(GO:0042393)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.5 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.1 GO:0003684 damaged DNA binding(GO:0003684)
0.0 49.1 GO:0001159 core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 1.6 GO:0000146 microfilament motor activity(GO:0000146)
0.0 1.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.4 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 1.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.9 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 8.8 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 1.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.7 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.9 GO:0051427 hormone receptor binding(GO:0051427)
0.0 0.9 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.3 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 1.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0042285 xylosyltransferase activity(GO:0042285)
0.0 0.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.7 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 6.3 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.3 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.7 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 1.7 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.1 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 1.0 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.3 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.1 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.0 0.2 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 0.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 2.2 GO:0042802 identical protein binding(GO:0042802)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 0.4 GO:0019003 GDP binding(GO:0019003)
0.0 1.3 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.0 GO:0004475 mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
0.0 0.0 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 6.4 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 0.3 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 0.3 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 8.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 0.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 4.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 4.4 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 3.1 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 1.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 0.5 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 1.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 3.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 2.3 PID ATM PATHWAY ATM pathway
0.1 1.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 0.6 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 2.0 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.1 1.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 1.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 2.0 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 2.9 PID NOTCH PATHWAY Notch signaling pathway
0.1 1.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 1.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 1.0 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 6.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.1 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.2 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.1 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.3 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.5 PID BMP PATHWAY BMP receptor signaling
0.0 0.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.4 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.6 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.7 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID BARD1 PATHWAY BARD1 signaling events
0.0 2.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.7 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.2 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.3 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.2 PID ARF 3PATHWAY Arf1 pathway
0.0 0.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.3 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 0.9 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.5 4.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.4 4.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.3 0.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 0.9 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.2 0.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 1.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 0.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 1.9 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2 4.1 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.2 2.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.3 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.1 5.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 2.0 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.1 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 4.6 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.1 1.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 0.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.9 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 2.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 1.0 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 0.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.8 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 0.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 1.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 2.9 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.1 1.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.7 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 1.6 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 1.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 0.9 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 0.7 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.1 0.4 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 1.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 3.4 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.1 0.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 1.1 REACTOME KINESINS Genes involved in Kinesins
0.1 1.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 0.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 5.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 0.6 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.7 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.8 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 1.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 3.8 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 1.1 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 2.9 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.5 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 3.8 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.9 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.6 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 1.1 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.0 0.5 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 0.3 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.5 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.5 REACTOME TRANSLATION Genes involved in Translation