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PRJEB1986: zebrafish developmental stages transcriptome

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Results for sox5

Z-value: 1.02

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Transcription factors associated with sox5

Gene Symbol Gene ID Gene Info
ENSDARG00000011582 SRY-box transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox5dr11_v1_chr4_-_17055950_17055950-0.445.9e-02Click!

Activity profile of sox5 motif

Sorted Z-values of sox5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_22339582 3.61 ENSDART00000134805
crystallin, gamma M2d1
chr9_-_22135420 1.90 ENSDART00000184959
crystallin, gamma M2d8
chr20_-_47704973 1.82 ENSDART00000174808
transcription factor AP-2 beta
chr9_-_22272181 1.64 ENSDART00000113174
crystallin, gamma M2d7
chr13_+_25449681 1.46 ENSDART00000101328
atonal bHLH transcription factor 7
chr22_-_10487490 1.41 ENSDART00000064798
asporin (LRR class 1)
chr1_-_30689004 1.40 ENSDART00000018827
dachshund c
chr3_-_30158395 1.34 ENSDART00000103502
si:ch211-152f23.5
chr24_+_24461558 1.29 ENSDART00000182424
basic helix-loop-helix family, member e22
chr24_+_24461341 1.27 ENSDART00000147658
basic helix-loop-helix family, member e22
chr7_+_39444843 1.24 ENSDART00000143999
ENSDART00000173554
ENSDART00000173698
ENSDART00000173754
ENSDART00000144075
ENSDART00000138192
ENSDART00000145457
ENSDART00000141750
ENSDART00000103056
ENSDART00000142946
ENSDART00000173748
troponin T type 3b (skeletal, fast)
chr19_-_43542568 1.20 ENSDART00000051720

chr6_+_43426599 1.15 ENSDART00000056457
microphthalmia-associated transcription factor a
chr8_+_23093155 1.14 ENSDART00000063075
zgc:100920
chr20_+_54383838 1.14 ENSDART00000157737
leucine rich repeat and fibronectin type III domain containing 5b
chr18_+_16246806 1.13 ENSDART00000142584
ALX homeobox 1
chr4_+_16323970 1.06 ENSDART00000190651

chr3_-_35602233 1.05 ENSDART00000055269
guanine nucleotide binding protein (G protein), gamma 13b
chr2_-_33455164 1.03 ENSDART00000134024
ENSDART00000132221
coiled-coil domain containing 24
chr8_+_31941650 1.00 ENSDART00000138217
5-hydroxytryptamine (serotonin) receptor 1A a
chr18_+_19972853 0.96 ENSDART00000180071
SKI family transcriptional corepressor 1b
chr23_-_32157865 0.96 ENSDART00000000876
nuclear receptor subfamily 4, group A, member 1
chr16_+_10318893 0.94 ENSDART00000055380
tubulin, beta 5
chr4_-_16412084 0.93 ENSDART00000188460
decorin
chr23_+_8797143 0.92 ENSDART00000132992
SRY (sex determining region Y)-box 18
chr16_-_33095161 0.90 ENSDART00000187648
dopey family member 1
chr2_+_50626476 0.89 ENSDART00000018150
neuronal differentiation 6b
chr11_-_6048490 0.89 ENSDART00000066164
plasmalemma vesicle associated protein b
chr20_-_14054083 0.88 ENSDART00000009549
Rh associated glycoprotein
chr20_+_39283849 0.87 ENSDART00000002481
ENSDART00000146683
scavenger receptor class A, member 3
chr9_+_32978302 0.85 ENSDART00000007630
nescient helix loop helix 2
chr1_-_38709551 0.85 ENSDART00000128794
glycoprotein M6Ab
chr12_-_35054354 0.84 ENSDART00000075351
zgc:112285
chr9_+_24008879 0.82 ENSDART00000190419
ENSDART00000191843
ENSDART00000148226
melanophilin b
chr18_+_27300700 0.82 ENSDART00000140444
pleckstrin homology domain containing, family A member 7a
chr8_-_34051548 0.80 ENSDART00000105204
pre-B-cell leukemia homeobox 3b
chr18_-_10995410 0.79 ENSDART00000136751
tetraspanin 33b
chr22_-_10541372 0.79 ENSDART00000179708
si:dkey-42i9.4
chr8_+_18830759 0.78 ENSDART00000089079
MPN domain containing
chr11_+_25257022 0.75 ENSDART00000156052
tumor protein p53 inducible nuclear protein 2
chr23_+_32335871 0.74 ENSDART00000149698
solute carrier family 39 (zinc transporter), member 5
chr2_+_32846602 0.73 ENSDART00000056649
transmembrane protein 53
chr11_+_39672874 0.73 ENSDART00000046663
ENSDART00000157659
calmodulin binding transcription activator 1b
chr22_+_661711 0.72 ENSDART00000113795
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr25_+_14507567 0.71 ENSDART00000015681
developing brain homeobox 1b
chr7_-_35515931 0.70 ENSDART00000193324
iroquois homeobox 6a
chr13_+_38520927 0.70 ENSDART00000137299
ENSDART00000111080
adhesion G protein-coupled receptor B3
chr17_-_30666037 0.70 ENSDART00000156509
ALK and LTK ligand 2b
chr3_-_28828242 0.68 ENSDART00000151445
si:ch211-76l23.4
chr14_-_26704829 0.67 ENSDART00000078563
neurogenin 1
chr13_-_40411908 0.67 ENSDART00000057094
ENSDART00000150091
NK2 homeobox 3
chr19_-_103289 0.66 ENSDART00000143118
adhesion G protein-coupled receptor B1b
chr18_-_20466061 0.66 ENSDART00000060311
progestin and adipoQ receptor family member Va
chr14_-_46442459 0.66 ENSDART00000158770
fibroblast growth factor binding protein 1b
chr14_+_38786298 0.66 ENSDART00000164440
si:ch211-195b11.3
chr8_+_21195420 0.66 ENSDART00000100234
ENSDART00000091307
collagen, type II, alpha 1a
chr12_+_6195191 0.64 ENSDART00000043236
ENSDART00000186420
protein kinase, cGMP-dependent, type Ib
chr19_+_19777437 0.63 ENSDART00000170662
homeobox A3a
chr15_+_28685892 0.63 ENSDART00000155815
ENSDART00000060244
neuro-oncological ventral antigen 2
chr16_+_28754403 0.62 ENSDART00000103340
S100 calcium binding protein V1
chr3_+_23742868 0.62 ENSDART00000153512
homeobox B3a
chr13_+_29773153 0.61 ENSDART00000144443
ENSDART00000133796
ENSDART00000141310
ENSDART00000139782
paired box 2a
chr5_-_67911111 0.61 ENSDART00000051833
GS homeobox 1
chr3_+_29714775 0.60 ENSDART00000041388
calcium channel, voltage-dependent, gamma subunit 2a
chr16_-_28856112 0.60 ENSDART00000078543
synaptotagmin XIb
chr19_+_37848830 0.59 ENSDART00000042276
ENSDART00000180872
neurexophilin 1
chr19_+_15571290 0.59 ENSDART00000131134
forkhead box O6 b
chr15_-_41689981 0.59 ENSDART00000059327
splA/ryanodine receptor domain and SOCS box containing 4b
chr2_+_56463167 0.59 ENSDART00000123392
RAB11B, member RAS oncogene family, b
chr3_+_23697997 0.59 ENSDART00000184299
ENSDART00000078466
homeobox B3a
chr13_+_12045758 0.58 ENSDART00000079398
ENSDART00000165467
ENSDART00000165880
guanine nucleotide binding protein (G protein), gamma 2
chr13_+_12045475 0.56 ENSDART00000163053
ENSDART00000160812
ENSDART00000158244
guanine nucleotide binding protein (G protein), gamma 2
chr25_+_26441054 0.56 ENSDART00000158607
death-associated protein kinase 2b
chr8_-_31938364 0.56 ENSDART00000137647
si:dkey-250l23.4
chr3_+_52999962 0.56 ENSDART00000104683
pre-B-cell leukemia transcription factor 4
chr10_+_23022263 0.55 ENSDART00000138955
si:dkey-175g6.2
chr7_-_18601206 0.54 ENSDART00000111636
si:ch211-119e14.2
chr19_-_38872650 0.54 ENSDART00000146641
adhesion G protein-coupled receptor B2
chr18_-_14836600 0.53 ENSDART00000045232
metastasis suppressor 1-like a
chr12_+_45677293 0.53 ENSDART00000152850
ENSDART00000153047
si:ch73-111m19.2
chr23_-_3759692 0.53 ENSDART00000028885
high mobility group AT-hook 1a
chr19_-_868187 0.53 ENSDART00000186626
eomesodermin homolog a
chr25_-_12923482 0.52 ENSDART00000161754

chr15_+_29728377 0.52 ENSDART00000099958
zgc:153372
chr4_-_6567355 0.52 ENSDART00000134820
ENSDART00000142087
forkhead box P2
chr5_+_56026031 0.51 ENSDART00000050970
frizzled class receptor 9a
chr23_+_36118738 0.51 ENSDART00000139319
homeobox C5a
chr15_-_20233105 0.51 ENSDART00000123910
protein phosphatase 1, regulatory (inhibitor) subunit 14Ab
chr18_+_30421528 0.50 ENSDART00000140908
Gse1 coiled-coil protein
chr12_-_33357655 0.50 ENSDART00000066233
ENSDART00000148165
solute carrier family 16 (monocarboxylate transporter), member 3
chr2_-_21170517 0.50 ENSDART00000135417
bmi1 polycomb ring finger oncogene 1b
chr14_-_24761132 0.50 ENSDART00000146299
slit homolog 3 (Drosophila)
chr16_+_23811554 0.50 ENSDART00000114336
si:dkey-7f3.9
chr11_-_3865472 0.49 ENSDART00000161426
GATA binding protein 2a
chr1_+_45958904 0.49 ENSDART00000108528
Rho guanine nucleotide exchange factor (GEF) 7b
chr13_+_29771463 0.48 ENSDART00000134424
ENSDART00000138332
ENSDART00000134330
ENSDART00000160944
ENSDART00000076992
ENSDART00000160921
paired box 2a
chr23_+_30730121 0.48 ENSDART00000134141
additional sex combs like transcriptional regulator 1
chr6_+_42819337 0.47 ENSDART00000046498
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa
chr14_+_21754521 0.46 ENSDART00000111839
lysine (K)-specific demethylase 2Ab
chr19_-_2318391 0.46 ENSDART00000012791
sp8 transcription factor a
chr6_+_18520859 0.46 ENSDART00000158263
si:dkey-10p5.10
chr7_-_31938938 0.46 ENSDART00000132353
brain-derived neurotrophic factor
chr1_+_14372680 0.46 ENSDART00000046874

chr10_-_28761454 0.46 ENSDART00000129400
activated leukocyte cell adhesion molecule a
chr19_+_20793388 0.46 ENSDART00000142463
thioredoxin-like 4A
chr3_+_52487695 0.45 ENSDART00000155451
si:ch211-241f5.3
chr16_+_29492937 0.45 ENSDART00000011497
cathepsin K
chr15_+_19797918 0.45 ENSDART00000113314
si:ch211-229d2.5
chr10_+_15255198 0.45 ENSDART00000139047
ENSDART00000172107
ENSDART00000183413
ENSDART00000185314
very low density lipoprotein receptor
chr16_-_7443388 0.44 ENSDART00000017445
PR domain containing 1a, with ZNF domain
chr19_+_19762183 0.44 ENSDART00000163611
ENSDART00000187604
homeobox A3a
chr17_-_30975978 0.44 ENSDART00000051697
Enah/Vasp-like a
chr19_+_43604643 0.44 ENSDART00000151168
si:ch211-199g17.9
chr16_+_40560622 0.43 ENSDART00000038294
tumor protein p53 inducible nuclear protein 1
chr3_-_31804481 0.43 ENSDART00000028270
glial fibrillary acidic protein
chr8_+_13106760 0.43 ENSDART00000029308
integrin, beta 4
chr14_-_25949951 0.43 ENSDART00000141304
secreted protein, acidic, cysteine-rich (osteonectin)
chr21_-_18991165 0.43 ENSDART00000012574
si:ch211-222n4.6
chr3_+_51684963 0.42 ENSDART00000091180
ENSDART00000183711
ENSDART00000159493
BAI1-associated protein 2a
chr19_+_43604256 0.42 ENSDART00000151080
ENSDART00000110305
si:ch211-199g17.9
chr16_+_19732543 0.42 ENSDART00000149901
ENSDART00000052927
twist family bHLH transcription factor 1b
chr13_+_28854438 0.42 ENSDART00000193407
ENSDART00000189554

chr15_-_41689684 0.42 ENSDART00000143447
splA/ryanodine receptor domain and SOCS box containing 4b
chr5_+_17624463 0.42 ENSDART00000183869
ENSDART00000081064
fibrosin-like 1
chr25_-_19139259 0.41 ENSDART00000067327
abhydrolase domain containing 2b
chr6_-_21873266 0.41 ENSDART00000151658
ENSDART00000151152
ENSDART00000151179
si:dkey-19e4.5
chr6_+_32382743 0.41 ENSDART00000190009
dedicator of cytokinesis 7
chr5_-_44843738 0.41 ENSDART00000003926
fructose-1,6-bisphosphatase 1a
chr17_-_30975707 0.41 ENSDART00000138346
Enah/Vasp-like a
chr14_+_31529958 0.41 ENSDART00000053026
family with sequence similarity 122B
chr7_+_20471315 0.40 ENSDART00000173714
si:dkey-19b23.13
chr11_+_39135050 0.40 ENSDART00000180571
ENSDART00000189685
cell division cycle 42
chr20_+_34915945 0.40 ENSDART00000153064
synaptosomal-associated protein, 25a
chr24_+_32411753 0.40 ENSDART00000058530
neuronal differentiation 6a
chr25_+_7321675 0.39 ENSDART00000104712
ENSDART00000142934
high mobility group 20A
chr9_+_11293830 0.39 ENSDART00000144440
wingless-type MMTV integration site family, member 6b
chr9_+_41040294 0.39 ENSDART00000000693
O-sialoglycoprotein endopeptidase-like 1
chr17_+_43595692 0.39 ENSDART00000156271
cilia and flagella associated protein 99
chr9_+_42607138 0.39 ENSDART00000138133
ENSDART00000002027
GULP, engulfment adaptor PTB domain containing 1a
chr23_-_33654889 0.38 ENSDART00000146180
cysteine-serine-rich nuclear protein 2
chr10_-_31104983 0.38 ENSDART00000186941
pbx/knotted 1 homeobox 2
chr18_-_14836862 0.38 ENSDART00000124843
metastasis suppressor 1-like a
chr21_+_7605803 0.38 ENSDART00000121813
WD repeat domain 41
chr14_-_36397768 0.37 ENSDART00000185199
ENSDART00000052562
spermatogenesis associated 4
chr10_+_15255012 0.37 ENSDART00000023766
very low density lipoprotein receptor
chr3_+_54047342 0.37 ENSDART00000178486
olfactomedin 2a
chr7_+_25003851 0.37 ENSDART00000144526
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr1_+_16466771 0.37 ENSDART00000162389
vacuolar protein sorting 37A
chr6_-_28943056 0.36 ENSDART00000065138
TBC1 domain family, member 23
chr8_+_7311478 0.36 ENSDART00000133358
ssu-2 homolog, related sequence 1
chr3_-_26244256 0.36 ENSDART00000103741
protein phosphatase 4, catalytic subunit a
chr6_-_32093830 0.36 ENSDART00000017695
forkhead box D3
chr4_-_19016396 0.36 ENSDART00000166160
si:dkey-31f5.11
chr7_+_47287307 0.36 ENSDART00000114669
dpy-19 like C-mannosyltransferase 3
chr23_-_33640959 0.36 ENSDART00000187599
ENSDART00000189475
cysteine-serine-rich nuclear protein 2
chr16_+_29492749 0.36 ENSDART00000179680
cathepsin K
chr19_-_45960191 0.35 ENSDART00000052434
ENSDART00000172732
eukaryotic translation initiation factor 3, subunit H, b
chr19_+_19761966 0.35 ENSDART00000163697
homeobox A3a
chr20_-_25369767 0.35 ENSDART00000180278
intersectin 2a
chr14_-_2588216 0.35 ENSDART00000188082
ENSDART00000167293
F-box and WD repeat domain containing 11a
chr5_-_28606916 0.35 ENSDART00000026107
ENSDART00000137717
tenascin C
chr2_-_30246781 0.34 ENSDART00000175071
elongin C paralog b
chr17_+_29276544 0.34 ENSDART00000049399
ankyrin repeat domain 9
chr16_-_21047872 0.34 ENSDART00000131582
chromobox homolog 3b
chr6_-_38418862 0.34 ENSDART00000104135
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr23_+_20523617 0.34 ENSDART00000176404
activity-dependent neuroprotector homeobox b
chr23_-_3759345 0.33 ENSDART00000132205
ENSDART00000137707
ENSDART00000189382
high mobility group AT-hook 1a
chr5_+_41793001 0.33 ENSDART00000136439
ENSDART00000190477
ENSDART00000192289
BCL tumor suppressor 7A
chr25_+_28253844 0.33 ENSDART00000151891
Ca++-dependent secretion activator 2
chr22_-_14128716 0.33 ENSDART00000140323
si:ch211-246m6.4
chr18_-_19484919 0.33 ENSDART00000177690
ENSDART00000184949
lactase-like b
chr5_-_20893993 0.33 ENSDART00000137603
si:ch211-225b11.4
chr19_+_19759577 0.32 ENSDART00000169480
homeobox A5a
chr23_-_33944597 0.32 ENSDART00000133223
si:dkey-190g6.2
chr24_-_3426620 0.32 ENSDART00000184346
NCK adaptor protein 1b
chr16_+_19033554 0.32 ENSDART00000182430
Rap guanine nucleotide exchange factor (GEF) 5b
chr14_-_41478265 0.32 ENSDART00000149886
ENSDART00000016002
tetraspanin 7
chr13_+_3938526 0.32 ENSDART00000012759
Yip1 domain family, member 3
chr21_-_27201495 0.32 ENSDART00000145013
zgc:77262
chr2_-_12079718 0.31 ENSDART00000155821
potassium channel, subfamily T, member 2
chr7_+_21180747 0.31 ENSDART00000185543
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr8_-_39978767 0.31 ENSDART00000083066
aspartate beta-hydroxylase domain containing 2
chr18_+_48428713 0.30 ENSDART00000076861
Fli-1 proto-oncogene, ETS transcription factor a
chr6_-_46742455 0.30 ENSDART00000011970
zgc:66479
chr18_+_6039141 0.30 ENSDART00000138972
si:ch73-386h18.1
chr13_+_11440389 0.30 ENSDART00000186463
zinc finger and BTB domain containing 18
chr23_-_30787932 0.30 ENSDART00000135771
myelin transcription factor 1a
chr11_-_16152400 0.29 ENSDART00000123665
actin related protein 2/3 complex, subunit 4, like
chr6_+_9872261 0.29 ENSDART00000045070
si:ch211-222n4.6
chr15_-_19705707 0.29 ENSDART00000047643
synaptotagmin-like 2b
chr11_+_16153207 0.29 ENSDART00000192356
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr8_+_20488322 0.29 ENSDART00000036630
zgc:101100
chr17_+_30545895 0.29 ENSDART00000076739
NHS-like 1a
chr11_+_16152316 0.29 ENSDART00000081054
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr25_-_29134000 0.28 ENSDART00000172027
ENSDART00000190447
poly (ADP-ribose) polymerase family, member 6b
chr7_-_38861741 0.28 ENSDART00000173629
ENSDART00000037361
ENSDART00000173953
PHD finger protein 21Aa
chr15_-_5799170 0.28 ENSDART00000142334
ENSDART00000171528
heterogeneous nuclear ribonucleoprotein L2
chr17_+_23968214 0.27 ENSDART00000183053
exportin 1 (CRM1 homolog, yeast) b
chr21_+_28502340 0.27 ENSDART00000077897
ENSDART00000140229
OTU deubiquitinase, ubiquitin aldehyde binding 1a
chr11_+_37612214 0.27 ENSDART00000172899
ENSDART00000077496
heterochromatin protein 1, binding protein 3

Network of associatons between targets according to the STRING database.

First level regulatory network of sox5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0045218 zonula adherens maintenance(GO:0045218)
0.2 1.1 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.2 0.9 GO:0015840 urea transport(GO:0015840)
0.2 1.4 GO:0060017 parathyroid gland development(GO:0060017)
0.2 0.5 GO:0060571 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.2 0.7 GO:0090386 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.2 0.5 GO:1902895 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.2 0.5 GO:0071896 protein localization to adherens junction(GO:0071896)
0.2 0.5 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.1 0.7 GO:0016322 neuron remodeling(GO:0016322)
0.1 1.1 GO:0021588 cerebellum formation(GO:0021588)
0.1 0.7 GO:0021516 dorsal spinal cord development(GO:0021516) anterior lateral line nerve development(GO:0048909)
0.1 0.4 GO:1990403 embryonic brain development(GO:1990403)
0.1 0.4 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.2 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 0.7 GO:0070376 ERK5 cascade(GO:0070375) regulation of ERK5 cascade(GO:0070376) positive regulation of ERK5 cascade(GO:0070378)
0.1 0.3 GO:0045887 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.1 1.0 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 0.6 GO:0003232 bulbus arteriosus development(GO:0003232)
0.1 1.0 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.3 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.1 0.4 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.4 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.1 0.7 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.4 GO:0097066 response to thyroid hormone(GO:0097066)
0.1 0.5 GO:0033687 osteoblast proliferation(GO:0033687)
0.1 0.2 GO:0032241 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833) messenger ribonucleoprotein complex assembly(GO:1990120)
0.1 1.7 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 0.2 GO:0030238 male sex determination(GO:0030238)
0.1 0.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 0.2 GO:0071548 cellular response to cortisol stimulus(GO:0071387) response to dexamethasone(GO:0071548)
0.1 1.2 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 1.2 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.0 0.9 GO:0007130 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0 1.0 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.9 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.3 GO:1900045 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.4 GO:0001709 cell fate determination(GO:0001709)
0.0 0.3 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 5.7 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.2 GO:0006844 acyl carnitine transport(GO:0006844)
0.0 0.2 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.1 GO:0097264 self proteolysis(GO:0097264)
0.0 0.2 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.2 GO:0033499 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.0 0.2 GO:0060760 positive regulation of cytokine-mediated signaling pathway(GO:0001961) positive regulation of response to cytokine stimulus(GO:0060760)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.0 0.5 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.6 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.0 0.2 GO:0061056 sclerotome development(GO:0061056)
0.0 0.6 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 0.9 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.5 GO:0045471 response to ethanol(GO:0045471)
0.0 0.2 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.0 0.2 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 0.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.5 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0 1.1 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.3 GO:0003160 endocardium morphogenesis(GO:0003160)
0.0 0.4 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0099612 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.0 0.1 GO:2000726 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.2 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 1.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.7 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.0 0.4 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.2 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.6 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 0.1 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.0 1.0 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 1.0 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.7 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.2 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.5 GO:0016525 negative regulation of angiogenesis(GO:0016525) negative regulation of vasculature development(GO:1901343) negative regulation of blood vessel morphogenesis(GO:2000181)
0.0 0.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.0 0.3 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.1 GO:1904036 negative regulation of epithelial cell apoptotic process(GO:1904036)
0.0 0.2 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.3 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.4 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.0 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.0 0.9 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.7 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.3 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.0 0.5 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.2 GO:0030816 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 0.4 GO:0060536 cartilage morphogenesis(GO:0060536)
0.0 0.4 GO:0042476 odontogenesis(GO:0042476)
0.0 0.5 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.4 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.0 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 1.0 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.1 0.7 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.4 GO:0071203 WASH complex(GO:0071203)
0.1 0.8 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.5 GO:0035517 PR-DUB complex(GO:0035517)
0.1 0.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.2 GO:0042382 paraspeckles(GO:0042382)
0.1 0.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.4 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 1.0 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.8 GO:0034361 very-low-density lipoprotein particle(GO:0034361)
0.1 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.7 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.2 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.9 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.1 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.0 0.2 GO:0098651 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 1.0 GO:0016605 PML body(GO:0016605)
0.0 1.0 GO:0005861 troponin complex(GO:0005861)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 1.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0033010 paranodal junction(GO:0033010)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.3 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.2 GO:0030027 lamellipodium(GO:0030027)
0.0 3.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.3 GO:0032590 neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0070097 delta-catenin binding(GO:0070097)
0.2 0.8 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.2 0.5 GO:0030792 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.2 0.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.4 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.7 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.1 0.6 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 2.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.7 GO:0070888 E-box binding(GO:0070888)
0.1 0.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 1.0 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.1 0.4 GO:0043998 H2A histone acetyltransferase activity(GO:0043998)
0.1 1.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.9 GO:0005522 profilin binding(GO:0005522)
0.1 2.8 GO:0005518 collagen binding(GO:0005518)
0.1 0.4 GO:0008126 acetylesterase activity(GO:0008126)
0.1 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.2 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.1 5.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.1 GO:0070122 isopeptidase activity(GO:0070122)
0.1 0.4 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.7 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.0 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.2 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.9 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.3 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.5 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.5 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.5 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.2 GO:0008515 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.3 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 1.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 8.2 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.8 GO:0046332 SMAD binding(GO:0046332)
0.0 0.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.6 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 1.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.3 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.4 GO:0098631 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0017022 myosin binding(GO:0017022)
0.0 0.0 GO:0015105 arsenite transmembrane transporter activity(GO:0015105)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 2.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.8 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.4 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.4 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 0.8 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 0.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.9 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 1.1 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.5 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.3 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME PI3K EVENTS IN ERBB4 SIGNALING Genes involved in PI3K events in ERBB4 signaling
0.0 0.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway