Project

PRJEB1986: zebrafish developmental stages transcriptome

Navigation
Downloads

Results for sox18

Z-value: 0.60

Motif logo

Transcription factors associated with sox18

Gene Symbol Gene ID Gene Info
ENSDARG00000058598 SRY-box transcription factor 18

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox18dr11_v1_chr23_+_8797143_87971430.155.5e-01Click!

Activity profile of sox18 motif

Sorted Z-values of sox18 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr23_+_42482137 1.63 ENSDART00000160199
cytochrome P450, family 2, subfamily AA, polypeptide 3
chr21_+_8341774 1.18 ENSDART00000129749
ENSDART00000055325
ENSDART00000133804
proteasome subunit beta 7
chr19_+_15440841 1.14 ENSDART00000182329
lin-28 homolog A (C. elegans)
chr18_-_40905901 1.06 ENSDART00000064848
peptidoglycan recognition protein 5
chr11_-_28614608 1.05 ENSDART00000065853
dehydrogenase/reductase (SDR family) member 3b
chr7_+_24814866 1.02 ENSDART00000173581
si:ch211-226l4.6
chr8_+_23726708 1.01 ENSDART00000142395
makorin, ring finger protein, 4
chr4_+_30776883 0.99 ENSDART00000169519
si:dkey-11d20.1
chr7_-_24995631 0.93 ENSDART00000173955
ENSDART00000173791
REST corepressor 2
chr5_-_30704390 0.91 ENSDART00000016709
intraflagellar transport 22 homolog (Chlamydomonas)
chr14_+_24277556 0.86 ENSDART00000122660
heterogeneous nuclear ribonucleoprotein A0a
chr17_+_16423721 0.86 ENSDART00000064233
EF-hand calcium binding domain 11
chr7_+_22688781 0.79 ENSDART00000173509
UDP glucuronosyltransferase 5 family, polypeptide G1
chr10_-_1718395 0.77 ENSDART00000137620
si:ch73-46j18.5
chr5_-_7513082 0.77 ENSDART00000158913
bone morphogenetic protein receptor, type IBa
chr3_+_34986837 0.77 ENSDART00000190341
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr11_+_17984354 0.73 ENSDART00000179986
RNA pseudouridylate synthase domain containing 4
chr14_-_24277805 0.72 ENSDART00000054243
D4, zinc and double PHD fingers family 2, like
chr9_+_44994214 0.70 ENSDART00000141434
retinol saturase (all-trans-retinol 13,14-reductase) like
chr2_-_27900518 0.70 ENSDART00000109561
ENSDART00000077720
zgc:163121
chr14_+_6962271 0.68 ENSDART00000148447
ENSDART00000149114
ENSDART00000149492
ENSDART00000148394
heterogeneous nuclear ribonucleoprotein A/Ba
chr3_+_22442445 0.68 ENSDART00000190921
WNK lysine deficient protein kinase 4b
chr4_+_13412030 0.68 ENSDART00000003694
cullin-associated and neddylation-dissociated 1
chr6_-_37460178 0.67 ENSDART00000153500
si:dkey-66a8.7
chr10_-_42237304 0.66 ENSDART00000140341
transcription factor 7 like 1a
chr3_+_25999477 0.65 ENSDART00000024316
minichromosome maintenance complex component 5
chr5_-_38107741 0.63 ENSDART00000156853
si:ch211-284e13.14
chr22_+_17118225 0.63 ENSDART00000135604
Fras1 related extracellular matrix 1b
chr11_+_17984167 0.60 ENSDART00000020283
ENSDART00000188329
RNA pseudouridylate synthase domain containing 4
chr12_-_44122412 0.59 ENSDART00000169094
si:ch73-329n5.3
chr17_+_50564070 0.57 ENSDART00000075150
bone morphogenetic protein 4
chr4_-_13973213 0.57 ENSDART00000067177
ENSDART00000144127
prickle homolog 1b
chr2_-_9971609 0.56 ENSDART00000137924
ENSDART00000048655
ENSDART00000131613
zgc:55943
chr9_+_32306862 0.56 ENSDART00000078513
MOB family member 4, phocein
chr5_+_61863996 0.56 ENSDART00000082879
symplekin
chr12_-_35105670 0.55 ENSDART00000153034
si:ch73-127m5.2
chr2_-_32262287 0.55 ENSDART00000056621
ENSDART00000039717
family with sequence similarity 49, member Ba
chr3_+_34159192 0.55 ENSDART00000151119
coactivator-associated arginine methyltransferase 1
chr12_+_18524953 0.55 ENSDART00000090332
neuralized E3 ubiquitin protein ligase 2
chr12_+_13348918 0.54 ENSDART00000181373
ribonuclease type III, nuclear
chr6_+_49052741 0.53 ENSDART00000011876
synaptonemal complex protein 1
chr25_+_35061044 0.53 ENSDART00000111706
si:dkey-108k21.14
chr2_+_32016516 0.52 ENSDART00000135040
MYC proto-oncogene, bHLH transcription factor b
chr6_-_37459759 0.51 ENSDART00000190666
si:dkey-66a8.7
chr14_-_35400671 0.51 ENSDART00000129676
LSM11, U7 small nuclear RNA associated
chr4_-_18741942 0.49 ENSDART00000145747
ENSDART00000066980
ENSDART00000186518
ataxin 10
chr1_-_35924495 0.49 ENSDART00000184424
SMAD family member 1
chr5_+_3892551 0.49 ENSDART00000134396
RPA interacting protein
chr2_+_31942390 0.47 ENSDART00000138684
ENSDART00000146758
ENSDART00000137921
OTU deubiquitinase with linear linkage specificity b
chr17_+_24597001 0.46 ENSDART00000191834
rearranged L-myc fusion
chr25_+_16043246 0.43 ENSDART00000186663
sb:cb470
chr15_-_8319988 0.41 ENSDART00000137552
si:ch211-113p18.3
chr8_-_17184482 0.40 ENSDART00000025803
polymerase (DNA directed), alpha 2
chr1_+_49435017 0.40 ENSDART00000124833
programmed cell death 11
chr16_+_23398369 0.40 ENSDART00000037694
S100 calcium binding protein A10b
chr22_+_1853999 0.39 ENSDART00000163288
zinc finger protein 1174
chr15_-_20779624 0.38 ENSDART00000181936
tyrosylprotein sulfotransferase 1
chr16_-_21903083 0.38 ENSDART00000165849
SET domain, bifurcated 1b
chr13_-_45063686 0.35 ENSDART00000130467
ENSDART00000136679
calcineurin-like EF-hand protein 1
chr4_-_37479395 0.35 ENSDART00000168299
ENSDART00000157864
si:dkey-106c17.2
chr22_+_2533514 0.34 ENSDART00000147967
si:ch73-92e7.4
chr8_+_37700090 0.33 ENSDART00000187885
ENSDART00000127633
adrenoceptor beta 3a
chr4_+_38981587 0.32 ENSDART00000142713
si:dkey-66k12.3
chr3_+_9588705 0.31 ENSDART00000172543
ENSDART00000104875
TNF receptor-associated protein 1
chr10_+_4235998 0.31 ENSDART00000169328
phospholipid phosphatase related 1
chr18_+_32444636 0.30 ENSDART00000164223
vomeronasal 2 receptor, a1
chr1_-_43987873 0.30 ENSDART00000108821

chr7_+_73827805 0.29 ENSDART00000109316
zgc:173587
chr24_+_38658334 0.28 ENSDART00000155735
si:ch73-70c5.1
chr15_-_31366742 0.28 ENSDART00000125585
odorant receptor, family D, subfamily 111, member 3
chr3_-_23470986 0.28 ENSDART00000113135
male-specific lethal 1 homolog a (Drosophila)
chr17_-_14780578 0.27 ENSDART00000154690
si:ch211-266o15.1
chr22_+_25352530 0.27 ENSDART00000176742
ENSDART00000113186
si:dkey-240e12.6
chr20_-_42534153 0.26 ENSDART00000061122
regulatory factor X, 6
chr22_+_9110998 0.26 ENSDART00000141520
NACHT, LRR and PYD domains-containing protein 15
chr21_-_30166097 0.25 ENSDART00000130676
heparin-binding EGF-like growth factor b
chr25_+_12849609 0.25 ENSDART00000168144
chemokine (C-C motif) ligand 33, duplicate 2
chr17_+_51682429 0.24 ENSDART00000004379
nucleolar protein 10
chr2_-_51593835 0.24 ENSDART00000168072
si:ch211-9d9.7
chr25_+_10987817 0.24 ENSDART00000156529
si:dkey-52p2.5
chr16_-_40508624 0.23 ENSDART00000075718
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr2_+_32016256 0.23 ENSDART00000005143
MYC proto-oncogene, bHLH transcription factor b
chr16_+_29586004 0.23 ENSDART00000149520
MCL1, BCL2 family apoptosis regulator b
chr18_-_7400075 0.23 ENSDART00000101250
si:dkey-30c15.13
chr20_+_34717403 0.21 ENSDART00000034252
prepronociceptin b
chr19_+_9113932 0.21 ENSDART00000060442
SET domain, bifurcated 1a
chr5_-_62317496 0.20 ENSDART00000180089
zgc:85789
chr11_+_5565082 0.20 ENSDART00000112590
ENSDART00000183207
si:ch73-40i7.5
chr13_-_18863680 0.20 ENSDART00000109277
leucine zipper, putative tumor suppressor 2a
chr3_-_38915998 0.20 ENSDART00000141886
si:dkey-106c17.2
chr22_+_1786230 0.19 ENSDART00000169318
ENSDART00000164948
zinc finger protein 1154
chr7_+_4922104 0.19 ENSDART00000135154
si:dkey-28d5.11
chr8_-_13486258 0.18 ENSDART00000137459
Pim proto-oncogene, serine/threonine kinase, related 104
chr2_+_21185903 0.17 ENSDART00000131369
si:dkey-29d8.3
chr16_-_24819860 0.17 ENSDART00000183874
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr24_+_11334733 0.17 ENSDART00000147552
ENSDART00000143171
si:dkey-12l12.1
chr5_+_39667272 0.16 ENSDART00000085388
bone morphogenetic protein 3
chr23_+_20795781 0.15 ENSDART00000128577
tetratricopeptide repeat domain 34
chr13_-_42724645 0.15 ENSDART00000046066
calpain 1, (mu/I) large subunit a
chr1_-_2061419 0.14 ENSDART00000058878
oxoglutarate (alpha-ketoglutarate) receptor 1a, tandem duplicate 3
chr15_+_11683114 0.14 ENSDART00000168233
si:dkey-31c13.1
chr11_-_396724 0.13 ENSDART00000184375

chr24_-_25184553 0.13 ENSDART00000166917
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr5_+_22459087 0.12 ENSDART00000134781

chr9_+_44832032 0.12 ENSDART00000002633
frizzled related protein
chr11_+_29671661 0.12 ENSDART00000024318
ENSDART00000165024
ring finger protein 207a
chr7_-_47282853 0.12 ENSDART00000169299
si:ch211-186j3.3
chr5_-_16475374 0.11 ENSDART00000134274
ENSDART00000136004
piwi-like RNA-mediated gene silencing 2
chr13_+_18659325 0.11 ENSDART00000147905
ENSDART00000188249
ENSDART00000134740
selenoprotein U 1a
chr18_-_7399767 0.10 ENSDART00000181689
si:dkey-30c15.13
chr1_-_57839070 0.10 ENSDART00000152571
si:dkey-1c7.3
chr23_+_4373360 0.09 ENSDART00000144061
protein tyrosine phosphatase domain containing 1b
chr3_-_33961589 0.08 ENSDART00000151533
immunoglobulin heavy constant delta
chr16_+_29586468 0.08 ENSDART00000148926
MCL1, BCL2 family apoptosis regulator b
chr23_-_10745288 0.08 ENSDART00000140745
ENSDART00000013768
eukaryotic translation initiation factor 4E family member 3
chr25_+_25202213 0.07 ENSDART00000150744
chemokine (C-C motif) ligand 39, duplicate 10
chr1_+_30551777 0.07 ENSDART00000112778
G protein-coupled receptor 183b
chr2_-_51521079 0.07 ENSDART00000165504

chr13_+_18659617 0.06 ENSDART00000133062
selenoprotein U 1a
chr16_-_9449712 0.06 ENSDART00000136522
PRP3 pre-mRNA processing factor 3 homolog (yeast)
chr21_+_14511685 0.05 ENSDART00000102099

chr8_-_29677300 0.05 ENSDART00000032407
ENSDART00000143623
perforin 1.6
chr8_-_13454281 0.05 ENSDART00000141959

chr5_-_7829657 0.05 ENSDART00000158374
PDZ and LIM domain 5a
chr1_-_50611031 0.05 ENSDART00000148285
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr20_+_26892761 0.05 ENSDART00000133293
finTRIM family, member 97
chr23_-_10831995 0.03 ENSDART00000142533
PDZ domain containing RING finger 3a
chr10_-_29733194 0.02 ENSDART00000149252
si:ch73-261i21.2
chr17_+_10570906 0.02 ENSDART00000182371
ENSDART00000176097
ENSDART00000110593
ENSDART00000169356
MGA, MAX dimerization protein a
chr14_+_30272891 0.02 ENSDART00000017122
N-acylsphingosine amidohydrolase (acid ceramidase) 1a
chr1_+_45707219 0.02 ENSDART00000143363
si:ch211-214c7.4
chr22_-_910926 0.02 ENSDART00000180075

chr7_+_4283299 0.01 ENSDART00000182026
kelch-like family member 33
chr5_+_42912966 0.01 ENSDART00000039973
RUN and FYVE domain containing 3
chr3_+_52145511 0.01 ENSDART00000078485
adhesion G protein-coupled receptor E14
chr25_-_35104083 0.00 ENSDART00000183252
ENSDART00000156727
si:dkey-108k21.21

Network of associatons between targets according to the STRING database.

First level regulatory network of sox18

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0010265 SCF complex assembly(GO:0010265)
0.2 1.3 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.2 0.6 GO:0033335 anal fin development(GO:0033335)
0.2 0.5 GO:0051026 meiotic DNA repair synthesis(GO:0000711) chiasma assembly(GO:0051026)
0.2 0.7 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.2 1.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 0.5 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 0.7 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 0.3 GO:0061178 insulin secretion involved in cellular response to glucose stimulus(GO:0035773) regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.1 1.1 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.5 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.8 GO:0003160 endocardium morphogenesis(GO:0003160)
0.1 0.5 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.3 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1 0.6 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.2 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.0 0.4 GO:0006477 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.6 GO:0021754 cell migration in hindbrain(GO:0021535) facial nucleus development(GO:0021754)
0.0 0.1 GO:0061400 positive regulation of transcription from RNA polymerase II promoter in response to calcium ion(GO:0061400)
0.0 0.6 GO:0090308 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 1.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.4 GO:0001881 receptor recycling(GO:0001881)
0.0 1.6 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.5 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.3 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.0 0.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.7 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.1 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.6 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.0 0.3 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.4 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.6 GO:0034112 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 0.9 GO:0016575 histone deacetylation(GO:0016575)
0.0 1.0 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 0.2 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0043073 germ cell nucleus(GO:0043073)
0.1 0.4 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.5 GO:0071797 LUBAC complex(GO:0071797)
0.1 0.9 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.2 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.6 GO:0042555 MCM complex(GO:0042555)
0.0 0.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 1.5 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.3 GO:0072487 MSL complex(GO:0072487)
0.0 0.7 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:1990923 PET complex(GO:1990923)
0.0 0.6 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.8 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.5 GO:0016605 PML body(GO:0016605)
0.0 0.9 GO:0000118 histone deacetylase complex(GO:0000118)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 1.1 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.5 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.1 0.8 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.3 GO:0051380 norepinephrine binding(GO:0051380)
0.1 1.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.6 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.8 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 1.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.6 GO:0043142 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1 0.6 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.4 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.7 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 1.0 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.3 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.3 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.2 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.5 GO:0017069 snRNA binding(GO:0017069)
0.0 0.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.5 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.6 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 1.2 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.5 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis