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PRJEB1986: zebrafish developmental stages transcriptome

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Results for sox17

Z-value: 0.78

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Transcription factors associated with sox17

Gene Symbol Gene ID Gene Info
ENSDARG00000101717 SRY-box transcription factor 17

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox17dr11_v1_chr7_-_58776400_587764000.771.0e-04Click!

Activity profile of sox17 motif

Sorted Z-values of sox17 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_22213297 1.79 ENSDART00000110656
ENSDART00000133149
crystallin, gamma M2d20
chr24_-_14712427 1.76 ENSDART00000176316
junctophilin 1a
chr9_-_22240052 1.72 ENSDART00000111109
crystallin, gamma M2d9
chr18_+_1837668 1.51 ENSDART00000164210

chr9_-_22299412 1.42 ENSDART00000139101
crystallin, gamma M2d21
chr21_+_11385031 1.40 ENSDART00000040598
carboxyl ester lipase, tandem duplicate 2
chr5_+_1278092 1.30 ENSDART00000147972
ENSDART00000159783
dynamin 1a
chr7_+_26100024 1.23 ENSDART00000173726
si:ch211-196f2.3
chr5_+_67812062 1.20 ENSDART00000158611
zgc:175280
chr2_+_45636034 1.18 ENSDART00000142230
fibronectin type III domain containing 7, related sequence 3
chr15_-_33896159 1.16 ENSDART00000159791
myelin associated glycoprotein
chr2_+_55199721 1.16 ENSDART00000016143
zmp:0000000521
chr16_-_28658341 1.16 ENSDART00000148456
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr16_+_43152727 1.11 ENSDART00000125590
ENSDART00000154493
ADAM metallopeptidase domain 22
chr25_+_4760489 1.10 ENSDART00000167399

chr7_+_23495986 1.08 ENSDART00000190739
ENSDART00000115299
ENSDART00000101423
ENSDART00000142401
zgc:109889
chr9_+_34641237 1.07 ENSDART00000133996
short stature homeobox
chr3_-_31079186 1.04 ENSDART00000145636
ENSDART00000140569
elongin B
elongin B
chr16_+_5184402 1.04 ENSDART00000156685
SOGA family member 3a
chr10_-_2522588 1.00 ENSDART00000081926

chr7_+_21841037 0.99 ENSDART00000077503
transmembrane 4 L six family member 5
chr18_+_10926197 0.93 ENSDART00000192387
tetratricopeptide repeat domain 38
chr3_+_18097700 0.89 ENSDART00000021634
info WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2a
chr22_+_14051245 0.87 ENSDART00000043711
ENSDART00000164259
aldehyde oxidase 6
chr5_-_69004007 0.86 ENSDART00000137443
ankyrin 1, erythrocytic a
chr15_+_19652807 0.84 ENSDART00000134321
ENSDART00000054426
lens intrinsic membrane protein 2.3
chr21_+_6328801 0.82 ENSDART00000163577
formin binding protein 1b
chr7_+_17992455 0.81 ENSDART00000089211
ENSDART00000190881
EH domain binding protein 1-like 1a
chr5_-_20678300 0.80 ENSDART00000088639
WSC domain containing 2
chr10_-_22845485 0.80 ENSDART00000079454
vesicle-associated membrane protein 2
chr22_+_14051894 0.80 ENSDART00000142548
aldehyde oxidase 6
chr12_-_7806007 0.79 ENSDART00000190359
ankyrin 3b
chr17_+_25289431 0.79 ENSDART00000161002
kelch repeat and BTB (POZ) domain containing 11
chr4_-_50301491 0.78 ENSDART00000163146
si:ch211-197e7.3
chr10_-_3258073 0.77 ENSDART00000113162
phosphatidylinositol 4-kinase, catalytic, alpha a
chr12_+_2870671 0.76 ENSDART00000165225
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) b
chr5_-_32274383 0.76 ENSDART00000122889
myosin, heavy polypeptide 1.3, skeletal muscle
chr17_+_51499789 0.75 ENSDART00000187701

chr9_-_22069364 0.74 ENSDART00000101938
crystallin, gamma M2b
chr18_-_15771551 0.74 ENSDART00000130931
ENSDART00000154079
si:ch211-219a15.3
chr11_-_44979281 0.74 ENSDART00000190972
LIM-domain binding 1b
chr17_-_6519423 0.73 ENSDART00000175626

chr3_-_34084387 0.72 ENSDART00000155365
immunoglobulin heavy variable 4-3
chr14_+_36738069 0.71 ENSDART00000105590
tryptophan 2,3-dioxygenase a
chr17_-_15382704 0.70 ENSDART00000005313
zgc:85722
chr5_-_32273777 0.70 ENSDART00000181242
myosin, heavy polypeptide 1.3, skeletal muscle
chr22_-_6884981 0.70 ENSDART00000124219

chr9_-_32813177 0.68 ENSDART00000012694
myxovirus (influenza virus) resistance C
chr11_-_40742424 0.67 ENSDART00000173399
ENSDART00000021369
taste receptor, type 1, member 3
chr16_-_25563508 0.67 ENSDART00000189642
ataxin 1b
chr7_+_49865049 0.67 ENSDART00000164165
solute carrier family 1 (glial high affinity glutamate transporter), member 2a
chr7_+_17992640 0.66 ENSDART00000173679
EH domain binding protein 1-like 1a
chr11_-_472547 0.65 ENSDART00000005923
zgc:77375
chr4_-_14328997 0.65 ENSDART00000091151
neural EGFL like 2b
chr1_+_37391141 0.64 ENSDART00000083593
ENSDART00000168647
SPARC-like 1
chr18_+_45504362 0.64 ENSDART00000140089
cyclic nucleotide gated channel beta 1a
chr1_-_44413629 0.64 ENSDART00000192747

chr5_-_68022631 0.64 ENSDART00000143199
WAS protein family, member 3a
chr16_-_50175069 0.63 ENSDART00000192979
lens intrinsic membrane protein 2.5
chr14_-_3174570 0.62 ENSDART00000163585
colony stimulating factor 1 receptor, a
chr8_+_6967108 0.62 ENSDART00000004588
acid-sensing (proton-gated) ion channel 1a
chr11_+_6152643 0.61 ENSDART00000012789
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr17_-_33289304 0.61 ENSDART00000135118
ENSDART00000040346
EFR3 homolog Ba (S. cerevisiae)
chr9_-_49464993 0.61 ENSDART00000181471
xin actin binding repeat containing 2b
chr19_-_15397946 0.61 ENSDART00000143480
human immunodeficiency virus type I enhancer binding protein 3a
chr11_-_29833698 0.60 ENSDART00000079149
X-linked Kx blood group (McLeod syndrome)
chr1_+_44800298 0.59 ENSDART00000073712
ENSDART00000187054
transmembrane protein 187
chr15_-_33904831 0.59 ENSDART00000164333
ENSDART00000165404
myelin associated glycoprotein
chr11_-_45385803 0.59 ENSDART00000173329
trafficking protein particle complex 10
chr2_-_12502495 0.58 ENSDART00000186781
dipeptidyl-peptidase 6b
chr9_-_22057658 0.57 ENSDART00000101944
crystallin, gamma MX, like 1
chr21_+_11105007 0.57 ENSDART00000128859
ENSDART00000193105
prolactin receptor a
chr20_+_46867816 0.57 ENSDART00000161469
si:ch73-21k16.1
chr19_-_36234185 0.56 ENSDART00000186003
CUB and Sushi multiple domains 2
chr9_-_16218097 0.55 ENSDART00000190503
myosin IB
chr6_+_30091811 0.54 ENSDART00000088403
melanotransferrin
chr1_+_53321878 0.54 ENSDART00000143909
TBC1 domain family, member 9 (with GRAM domain)
chr6_+_40714811 0.54 ENSDART00000153868
coiled-coil domain containing 36
chr21_+_18353703 0.54 ENSDART00000181396
ENSDART00000166359
si:ch73-287m6.1
chr5_-_26181863 0.54 ENSDART00000098500
coiled-coil domain containing 125
chr9_-_46276626 0.53 ENSDART00000165238
histone deacetylase 4
chr13_+_29462249 0.53 ENSDART00000147903
leucine-rich repeat, immunoglobulin-like and transmembrane domains 1a
chr6_+_37894914 0.53 ENSDART00000148817
oculocutaneous albinism II
chr6_-_442163 0.53 ENSDART00000163564
ENSDART00000189134
ENSDART00000169789
GRB2-related adaptor protein 2b
chr12_-_41662327 0.53 ENSDART00000191602
ENSDART00000170423
Janus kinase and microtubule interacting protein 3
chr21_-_7178348 0.52 ENSDART00000187467
family with sequence similarity 69, member B
chr11_+_11201096 0.52 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myomesin 2a
chr3_+_15279016 0.52 ENSDART00000182005
aspartate beta-hydroxylase domain containing 1
chr6_-_7842078 0.52 ENSDART00000065507
phospholipid phosphatase related 2b
chr17_-_52595932 0.51 ENSDART00000127225
si:ch211-173a9.7
chr19_-_657439 0.51 ENSDART00000167100
solute carrier family 6 (neutral amino acid transporter), member 18
chr7_-_24373662 0.50 ENSDART00000173865
si:dkey-11k2.7
chr25_-_1720736 0.50 ENSDART00000097256
solute carrier family 6 member 13
chr15_+_863931 0.50 ENSDART00000154083
si:dkey-7i4.12
chr3_+_36366053 0.50 ENSDART00000181140
regulator of G protein signaling 9a
chr7_-_39378903 0.49 ENSDART00000173659
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr1_+_6817292 0.49 ENSDART00000145822
ENSDART00000092118
erb-b2 receptor tyrosine kinase 4a
chr15_-_37543591 0.49 ENSDART00000180400
lysine (K)-specific methyltransferase 2Bb
chr2_+_22409249 0.49 ENSDART00000182915
zgc:56628
chr9_+_34127005 0.48 ENSDART00000167384
ENSDART00000078065
coagulation factor V
chr4_-_3064101 0.48 ENSDART00000135701
pleckstrin homology domain containing, family A member 5
chr15_-_43768776 0.47 ENSDART00000170398
glutamate receptor, metabotropic 5b
chr17_+_50127648 0.46 ENSDART00000156460
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr1_+_37391716 0.46 ENSDART00000191986
SPARC-like 1
chr1_-_23110740 0.46 ENSDART00000171848
ENSDART00000086797
ENSDART00000189344
ENSDART00000190858
adhesion G protein-coupled receptor L3.1
chr23_+_25201077 0.45 ENSDART00000136675
si:dkey-151g10.3
chr10_+_15454745 0.45 ENSDART00000129441
ENSDART00000123935
ENSDART00000163446
ENSDART00000087680
ENSDART00000193752
erbb2 interacting protein
chr1_-_46981134 0.45 ENSDART00000130607
pbx/knotted 1 homeobox 1.2
chr5_-_69314495 0.45 ENSDART00000182335
smoothelin b
chr7_-_3927813 0.45 ENSDART00000172991
ENSDART00000173392
si:dkey-88n24.12
chr11_-_575786 0.45 ENSDART00000019997
makorin, ring finger protein, 2
chr7_+_66565572 0.44 ENSDART00000180250
transmembrane protein 176l.3b
chr22_-_26175237 0.44 ENSDART00000108737
complement component c3b, tandem duplicate 2
chr24_-_38079261 0.44 ENSDART00000105662
C-reactive protein 1
chr23_+_34321237 0.44 ENSDART00000173272
plexin A1a
chr25_+_20140926 0.44 ENSDART00000121989
caldesmon 1b
chr5_-_33606729 0.43 ENSDART00000137073
si:dkey-34e4.1
chr18_-_16181952 0.43 ENSDART00000157824
solute carrier family 6 (neutral amino acid transporter), member 15
chr16_+_11623956 0.43 ENSDART00000137788
chemokine (C-X-C motif) receptor 3, tandem duplicate 1
chr4_-_49582758 0.43 ENSDART00000180834
ENSDART00000187608
si:dkey-159n16.2
chr12_-_14551077 0.43 ENSDART00000188717

chr17_-_6399920 0.43 ENSDART00000022010
human immunodeficiency virus type I enhancer binding protein 2b
chr22_+_1868983 0.42 ENSDART00000160135
si:dkey-15h8.17
chr11_+_575665 0.42 ENSDART00000122133
MKRN2 opposite strand, tandem duplicate 1
chr20_+_18945057 0.41 ENSDART00000035447
myotubularin related protein 9
chr21_-_21530868 0.41 ENSDART00000174231
odorant receptor, family H, subfamily 133, member 9
chr7_-_52096498 0.41 ENSDART00000098688
ENSDART00000098690
cytochrome P450, family 2, subfamily X, polypeptide 10.2
chr6_-_39158953 0.40 ENSDART00000050682
signal transducer and activator of transcription 2
chr15_+_16521785 0.40 ENSDART00000062191
polypeptide N-acetylgalactosaminyltransferase 17
chr24_-_33276139 0.40 ENSDART00000128943
nuclear receptor binding protein 2b
chr3_+_15773991 0.39 ENSDART00000089923
zinc finger protein 652
chr19_-_22498629 0.39 ENSDART00000185370
plectin a
chr7_-_68373495 0.39 ENSDART00000167440
zinc finger homeobox 3
chr3_-_12381271 0.39 ENSDART00000171068
ENSDART00000157475
coronin 7
chr11_-_45385602 0.38 ENSDART00000166691
trafficking protein particle complex 10
chr24_+_26406770 0.38 ENSDART00000110011
si:ch211-230g15.5
chr8_-_9684872 0.38 ENSDART00000132158
protein tyrosine phosphatase, non-receptor type 18
chr24_-_25673405 0.38 ENSDART00000186081
ENSDART00000110241
ENSDART00000142351
connector enhancer of kinase suppressor of Ras 2a
chr14_+_29609245 0.38 ENSDART00000043058
si:dkey-34l15.2
chr6_+_54538948 0.38 ENSDART00000149270
tubby like protein 1b
chr21_-_1742159 0.37 ENSDART00000151049
one cut homeobox 2
chr21_-_39628771 0.37 ENSDART00000183995
aldolase C, fructose-bisphosphate, b
chr2_-_9260002 0.37 ENSDART00000057299
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5a
chr2_-_51630555 0.37 ENSDART00000171746
polymeric immunoglobulin receptor
chr17_-_52594756 0.37 ENSDART00000167288
si:ch211-173a9.7
chr1_-_656693 0.37 ENSDART00000170483
ENSDART00000166786
amyloid beta (A4) precursor protein a
chr19_-_22621991 0.36 ENSDART00000175106
plectin a
chr11_-_42134968 0.36 ENSDART00000187115

chr16_-_52736549 0.36 ENSDART00000146607
antizyme inhibitor 1a
chr14_+_25464681 0.36 ENSDART00000067500
ENSDART00000187601
si:dkey-280e21.3
chr3_-_8510201 0.36 ENSDART00000009151

chr19_+_10493223 0.36 ENSDART00000180826
si:ch211-171h4.6
chr17_+_13031497 0.35 ENSDART00000115208
F-box protein 33
chr4_-_75803810 0.35 ENSDART00000163517
si:ch211-203c5.3
chr22_+_12361317 0.35 ENSDART00000189963
ENSDART00000159614
R3H domain containing 1
chr14_-_1313480 0.35 ENSDART00000097748
interleukin 21
chr5_-_30074332 0.35 ENSDART00000147963
beta-carotene oxygenase 2a
chr19_+_9305964 0.35 ENSDART00000136241
si:ch73-15n24.1
chr14_+_2076215 0.34 ENSDART00000190062

chr23_-_45319592 0.34 ENSDART00000189861
coiled-coil domain containing 171
chr5_+_45990046 0.34 ENSDART00000084024
synaptic vesicle glycoprotein 2C
chr1_-_46650022 0.34 ENSDART00000148759
ENSDART00000053222
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chr23_-_10048533 0.34 ENSDART00000166663
plexin b1a
chr4_-_5371639 0.34 ENSDART00000150697
si:dkey-14d8.1
chr19_-_41213718 0.34 ENSDART00000077121
pyruvate dehydrogenase kinase, isozyme 4
chr1_-_44037843 0.34 ENSDART00000160276
si:ch73-109d9.3
chr11_-_8320868 0.33 ENSDART00000160570
si:ch211-247n2.1
chr2_-_17492486 0.33 ENSDART00000189464
lysine (K)-specific demethylase 4A, genome duplicate b
chr5_-_5243079 0.33 ENSDART00000130576
ENSDART00000164377
multivesicular body subunit 12Ba
chr4_-_38476901 0.33 ENSDART00000167124
si:ch211-209n20.59
chr17_-_19963718 0.33 ENSDART00000154251
cholinergic receptor, muscarinic 3a
chr21_+_24536233 0.33 ENSDART00000145448
ENSDART00000109886
ENSDART00000135191
anaphase promoting complex subunit 13
chr23_+_16774589 0.32 ENSDART00000104791
zgc:153722
chr4_-_2975461 0.32 ENSDART00000150794
pleckstrin homology domain containing, family A member 5
chr5_-_8602937 0.32 ENSDART00000157765
RPTOR independent companion of MTOR, complex 2 a
chr25_+_22682065 0.32 ENSDART00000129484
Usher syndrome 1C
chr2_+_36007449 0.32 ENSDART00000161837
laminin, gamma 2
chr20_-_45062514 0.32 ENSDART00000183529
ENSDART00000182955
kelch-like family member 29
chr21_-_2248239 0.32 ENSDART00000169448
si:ch73-299h12.1
chr11_-_25213651 0.32 ENSDART00000097316
ENSDART00000152186
myosin, heavy chain 7B, cardiac muscle, beta a
chr7_+_18017756 0.32 ENSDART00000173717
EH domain binding protein 1-like 1a
chr12_-_31103906 0.31 ENSDART00000189099
ENSDART00000121527
ENSDART00000185635
ENSDART00000183754
transcription factor 7 like 2
chr22_-_26236188 0.31 ENSDART00000162640
ENSDART00000167169
ENSDART00000138595
complement component c3b, tandem duplicate 1
chr1_+_29281764 0.31 ENSDART00000112106
family with sequence similarity 155, member A
chr20_-_35040041 0.31 ENSDART00000131919
kinesin family member 26Bb
chr17_-_20558961 0.31 ENSDART00000155993
SH3 and PX domains 2Ab
chr11_-_42918971 0.30 ENSDART00000052912
protocadherin 20
chr1_-_12278056 0.30 ENSDART00000139336
ENSDART00000137463
complexin 2, like
chr23_-_27101600 0.30 ENSDART00000139231
signal transducer and activator of transcription 6, interleukin-4 induced
chr22_+_1352192 0.29 ENSDART00000169629
zinc finger 45 like
chr17_+_51520073 0.28 ENSDART00000189646
ENSDART00000170951
ENSDART00000189492
peroxidasin
chr23_-_26652273 0.28 ENSDART00000112124
ENSDART00000111029
heparan sulfate proteoglycan 2
chr2_+_51818039 0.28 ENSDART00000170353
activin A receptor type 2Bb
chr4_+_25950372 0.28 ENSDART00000125767
methionyl aminopeptidase 2a
chr4_-_24031924 0.28 ENSDART00000017443
cugbp, Elav-like family member 2
chr22_+_7923713 0.28 ENSDART00000167210

chr6_+_4299164 0.27 ENSDART00000159759
neurobeachin-like 1
chr21_-_39546737 0.27 ENSDART00000006971
septin 4a
chr8_-_45277370 0.27 ENSDART00000146364
ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr22_+_12361489 0.27 ENSDART00000182483
R3H domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of sox17

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:1903826 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.2 1.0 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.2 0.5 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.2 0.6 GO:0042481 regulation of macrophage chemotaxis(GO:0010758) positive regulation of macrophage chemotaxis(GO:0010759) regulation of odontogenesis(GO:0042481) mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675)
0.1 0.6 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.5 GO:0090299 regulation of neural crest formation(GO:0090299)
0.1 1.4 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 1.7 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.3 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.1 0.4 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.3 GO:0042560 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.1 0.7 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.1 0.6 GO:0070207 protein homotrimerization(GO:0070207)
0.1 0.3 GO:0044803 virion assembly(GO:0019068) virus maturation(GO:0019075) multi-organism membrane organization(GO:0044803) viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.1 1.6 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 0.3 GO:0010226 response to lithium ion(GO:0010226)
0.1 0.2 GO:0060907 macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907)
0.1 0.2 GO:0015942 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 0.3 GO:0070084 protein initiator methionine removal(GO:0070084)
0.1 0.5 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 0.4 GO:1902267 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 0.5 GO:0042438 melanin biosynthetic process(GO:0042438)
0.1 0.9 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.2 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.1 0.7 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.3 GO:0034695 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.1 0.2 GO:0007405 neuroblast proliferation(GO:0007405) establishment of centrosome localization(GO:0051660)
0.1 0.5 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 0.8 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.3 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.3 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.3 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 5.9 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.2 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.0 0.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0016119 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 0.8 GO:1902287 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.3 GO:0071233 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.0 1.2 GO:0009636 response to toxic substance(GO:0009636)
0.0 1.0 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 0.1 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.0 0.5 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.4 GO:0034340 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.1 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 0.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.7 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.5 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.5 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.5 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.2 GO:0038026 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) reelin-mediated signaling pathway(GO:0038026)
0.0 0.1 GO:1902514 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 1.1 GO:0030282 bone mineralization(GO:0030282)
0.0 0.3 GO:0001964 startle response(GO:0001964)
0.0 0.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 1.0 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.8 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.1 GO:0032206 positive regulation of telomere maintenance(GO:0032206) regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
0.0 0.5 GO:0006826 iron ion transport(GO:0006826)
0.0 0.6 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.4 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.2 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.1 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 1.0 GO:0048741 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 0.2 GO:0039023 pronephric duct morphogenesis(GO:0039023)
0.0 0.3 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 0.7 GO:0043534 blood vessel endothelial cell migration(GO:0043534)
0.0 0.3 GO:0016233 telomere capping(GO:0016233)
0.0 0.2 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.1 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045)
0.0 0.2 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.0 GO:1904088 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.0 0.0 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.3 GO:0070831 basement membrane assembly(GO:0070831)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0030314 junctional membrane complex(GO:0030314)
0.2 0.7 GO:0044316 cone cell pedicle(GO:0044316)
0.2 1.0 GO:1990071 TRAPPII protein complex(GO:1990071)
0.2 1.0 GO:0030891 VCB complex(GO:0030891)
0.1 1.7 GO:0031209 SCAR complex(GO:0031209)
0.1 0.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.6 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 0.3 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0032997 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.0 0.8 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.3 GO:0002141 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.0 1.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.6 GO:0005903 brush border(GO:0005903)
0.0 0.5 GO:0031430 M band(GO:0031430)
0.0 0.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0070187 telosome(GO:0070187)
0.0 0.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.2 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.7 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.1 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.3 GO:0043195 terminal bouton(GO:0043195)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.2 GO:0016459 myosin complex(GO:0016459)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0004031 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.5 1.4 GO:0004771 sterol esterase activity(GO:0004771)
0.4 1.2 GO:0015562 protein-transmembrane transporting ATPase activity(GO:0015462) efflux transmembrane transporter activity(GO:0015562)
0.2 0.7 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.2 1.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 1.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.2 0.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.6 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 0.9 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.6 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 1.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 1.8 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.8 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.7 GO:0030274 LIM domain binding(GO:0030274)
0.1 7.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.3 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 0.4 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.5 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.1 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.4 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.7 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.8 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.6 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0019767 immunoglobulin receptor activity(GO:0019763) IgE receptor activity(GO:0019767)
0.0 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.3 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.5 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.3 GO:0070728 leucine binding(GO:0070728)
0.0 1.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.6 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.5 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.3 GO:0030332 cyclin binding(GO:0030332)
0.0 0.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.3 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.4 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.5 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.9 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.3 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 0.6 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 0.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 0.9 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.6 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.3 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.2 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.2 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription