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PRJEB1986: zebrafish developmental stages transcriptome

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Results for sox14+sox14-1+sox21a

Z-value: 1.07

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Transcription factors associated with sox14+sox14-1+sox21a

Gene Symbol Gene ID Gene Info
ENSDARG00000031664 SRY-box transcription factor 21a
ENSDARG00000070929 SRY-box transcription factor 14
ENSDARG00000111842 SRY-box transcription factor 21a
ENSDARG00000111969 SRY-box transcription factor 14

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox14dr11_v1_chr6_-_26559921_265599210.662.0e-03Click!
FQ377628.2dr11_v1_chr2_-_22575851_22575851-0.165.2e-01Click!
sox21adr11_v1_chr6_+_7414215_7414215-0.009.8e-01Click!

Activity profile of sox14+sox14-1+sox21a motif

Sorted Z-values of sox14+sox14-1+sox21a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_6641223 2.15 ENSDART00000023793
major intrinsic protein of lens fiber b
chr5_-_30615901 2.08 ENSDART00000147769
si:ch211-117m20.5
chr14_+_46313396 2.01 ENSDART00000047525
crystallin, beta A1, like 1
chr12_+_17865374 1.78 ENSDART00000169019
transmembrane protein 130
chr6_-_39764995 1.74 ENSDART00000085277
phosphofructokinase, muscle b
chr14_+_46313135 1.68 ENSDART00000172902
crystallin, beta A1, like 1
chr9_-_11560110 1.56 ENSDART00000176941
crystallin, beta A2b
chr8_-_13541514 1.42 ENSDART00000063834
zgc:86586
chr25_+_25202213 1.37 ENSDART00000150744
chemokine (C-C motif) ligand 39, duplicate 10
chr12_-_4346085 1.34 ENSDART00000112433
carbonic anhydrase XV c
chr13_+_30912385 1.34 ENSDART00000182642
dorsal root ganglia homeobox
chr6_-_39765546 1.33 ENSDART00000185767
phosphofructokinase, muscle b
chr8_-_20243389 1.28 ENSDART00000184904
alkaline ceramidase 1
chr5_-_41531629 1.19 ENSDART00000051082
aldo-keto reductase family 1, member A1a (aldehyde reductase)
chr8_+_18830759 1.16 ENSDART00000089079
MPN domain containing
chr7_+_31891110 1.14 ENSDART00000173883
myosin binding protein C, cardiac
chr9_-_11560427 1.10 ENSDART00000127942
ENSDART00000061442
crystallin, beta A2b
chr21_-_16113799 1.10 ENSDART00000187848
cytochrome b561 family, member A3b
chr1_-_55118745 1.10 ENSDART00000133915
SERTA domain containing 2a
chr1_+_59088205 1.05 ENSDART00000150649
ENSDART00000100197
zgc:173915
chr10_+_44042033 0.99 ENSDART00000190006
ENSDART00000046172
crystallin, beta A4
chr23_+_36130883 0.99 ENSDART00000103132
homeobox C4a
chr6_+_4229360 0.97 ENSDART00000191347
ENSDART00000130642

chr12_+_22576404 0.95 ENSDART00000172053
capping protein (actin filament), gelsolin-like b
chr21_-_16113477 0.94 ENSDART00000147588
cytochrome b561 family, member A3b
chr2_-_6112862 0.91 ENSDART00000164269
peroxiredoxin 1
chr9_-_23922011 0.90 ENSDART00000145734
collagen, type VI, alpha 3
chr6_+_43426599 0.90 ENSDART00000056457
microphthalmia-associated transcription factor a
chr2_+_36004381 0.79 ENSDART00000098706
laminin, gamma 2
chr21_+_26390549 0.79 ENSDART00000185643
thymosin, beta
chr8_-_17067364 0.78 ENSDART00000132687
RAB3C, member RAS oncogene family
chr12_-_17655683 0.77 ENSDART00000066411
discs, large (Drosophila) homolog-associated protein 5
chr14_-_2189889 0.77 ENSDART00000181557
ENSDART00000106707
protocadherin 2 alpha b 9
protocadherin 2 alpha b 11
chr14_+_11457500 0.77 ENSDART00000169202
si:ch211-153b23.5
chr1_-_33557915 0.75 ENSDART00000075632
cAMP responsive element binding protein 1a
chr22_-_10019768 0.74 ENSDART00000162077

chr18_+_17725410 0.74 ENSDART00000090608
ring finger and SPRY domain containing 1
chr9_-_51436377 0.74 ENSDART00000006612
T-box, brain, 1b
chr17_-_46457622 0.72 ENSDART00000130215
transmembrane protein 179
chr4_-_17805128 0.71 ENSDART00000128988
Spi-2 proto-oncogene
chr4_-_27301356 0.69 ENSDART00000100444
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5a
chr18_-_38087875 0.68 ENSDART00000111301
leucine zipper protein 2
chr25_-_13023569 0.68 ENSDART00000167232
chemokine (C-C motif) ligand 39, duplicate 1
chr2_-_45510699 0.68 ENSDART00000024034
ENSDART00000145634
G protein signaling modulator 2
chr7_-_19915414 0.67 ENSDART00000144180
zgc:110591
chr2_+_38025260 0.65 ENSDART00000075905
heterogeneous nuclear ribonucleoprotein C
chr11_+_15613218 0.63 ENSDART00000066033
growth differentiation factor 11
chr12_+_28955766 0.62 ENSDART00000123417
ENSDART00000139347
zinc finger protein 668
chr17_-_37214196 0.62 ENSDART00000128715
kinesin family member 3Cb
chr15_-_33818872 0.62 ENSDART00000158325
NEDD4 binding protein 2-like 2
chr16_+_35535171 0.61 ENSDART00000167001
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr7_+_22801465 0.61 ENSDART00000052862
ENSDART00000173633
RNA binding motif protein 4.1
chr1_+_218524 0.61 ENSDART00000109529
transmembrane and coiled-coil domains 3
chr18_+_20034023 0.60 ENSDART00000139441
mortality factor 4 like 1
chr3_-_25814097 0.59 ENSDART00000169706
netrin 1b
chr18_-_13203351 0.59 ENSDART00000039585
ENSDART00000134920
ENSDART00000142942
kelch-like family member 36
chr13_-_31470439 0.58 ENSDART00000076574
reticulon 1a
chr7_+_38380135 0.58 ENSDART00000174005
rhophilin, Rho GTPase binding protein 2
chr23_-_30727596 0.58 ENSDART00000060193
THAP domain containing, apoptosis associated protein 3
chr9_-_23922778 0.58 ENSDART00000135769
collagen, type VI, alpha 3
chr8_-_30204650 0.56 ENSDART00000133209
zgc:162939
chr6_-_52723901 0.55 ENSDART00000033949
oxidative stress responsive serine-rich 1
chr7_-_20611039 0.55 ENSDART00000170422
si:dkey-19b23.8
chr4_-_22749553 0.54 ENSDART00000040033
nucleoporin 107
chr4_-_2052687 0.54 ENSDART00000138291
ENSDART00000150844
cleavage and polyadenylation specific factor 6
chr1_+_29140884 0.54 ENSDART00000053926
ENSDART00000150133
ankyrin repeat domain 10a
chr1_-_49225890 0.53 ENSDART00000111598
chemokine (C-X-C motif) ligand 18b
chr7_-_30694177 0.53 ENSDART00000191633
myosin IE, a
chr18_+_46151505 0.52 ENSDART00000015034
ENSDART00000141287
biliverdin reductase B
chr3_-_25275364 0.51 ENSDART00000163782
ENSDART00000145420
ENSDART00000133718
ENSDART00000055492
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr23_-_19715799 0.50 ENSDART00000142072
ENSDART00000032744
ENSDART00000131860
ribosomal protein L10
chr16_+_28578648 0.50 ENSDART00000149566
N-myristoyltransferase 2
chr5_-_29559758 0.50 ENSDART00000051471
ENSDART00000167115
negative elongation factor complex member B
chr19_+_46222918 0.50 ENSDART00000158703
vacuolar protein sorting 28 (yeast)
chr3_-_5644028 0.49 ENSDART00000019957
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Ab
chr6_+_37623693 0.48 ENSDART00000144812
ENSDART00000182709
tubulin, gamma complex associated protein 5
chr6_-_40885496 0.48 ENSDART00000189857
sirtuin 4
chr17_+_14711765 0.47 ENSDART00000012889
connexin 28.6
chr7_+_20019125 0.47 ENSDART00000186391
B-cell CLL/lymphoma 6, member B
chr25_-_12982193 0.46 ENSDART00000159617
chemokine (C-C motif) ligand 39, duplicate 5
chr16_+_35535375 0.46 ENSDART00000171675
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr22_+_24770744 0.45 ENSDART00000142882
si:rp71-23d18.4
chr1_+_26356360 0.45 ENSDART00000113020
tet methylcytosine dioxygenase 2
chr1_+_54901028 0.44 ENSDART00000137352
zinc finger, FYVE domain containing 27
chr20_+_9128829 0.44 ENSDART00000064144
ENSDART00000137450
bisphosphate nucleotidase 1
chr25_+_10793478 0.43 ENSDART00000058339
ENSDART00000134923
adaptor-related protein complex 3, sigma 2 subunit
chr11_-_27838621 0.43 ENSDART00000173087
eukaryotic translation initiation factor 4 gamma, 3a
chr19_-_20430892 0.42 ENSDART00000111409
TBC1 domain family, member 5
chr7_+_25913225 0.42 ENSDART00000129924
high mobility group box 3a
chr11_-_24063196 0.42 ENSDART00000036513
tribbles pseudokinase 3
chr6_+_584632 0.42 ENSDART00000151150
zgc:92360
chr19_-_3916075 0.41 ENSDART00000161799
si:ch73-281i18.7
chr10_+_32662886 0.41 ENSDART00000099841
RAD51 paralog C
chr5_+_36752943 0.41 ENSDART00000017138
exocyst complex component 3-like 2a
chr20_+_29691118 0.40 ENSDART00000164121
membrane bound O-acyltransferase domain containing 2b
chr2_-_36933472 0.40 ENSDART00000170405

chr12_-_19862912 0.40 ENSDART00000145788
shisa family member 9a
chr14_-_246342 0.40 ENSDART00000054823
aurora kinase B
chr19_+_46222428 0.40 ENSDART00000183984
vacuolar protein sorting 28 (yeast)
chr13_+_30912938 0.39 ENSDART00000190003
dorsal root ganglia homeobox
chr25_+_32474031 0.39 ENSDART00000152124
sulfide quinone oxidoreductase
chr23_-_3758637 0.39 ENSDART00000131536
ENSDART00000139408
ENSDART00000137826
high mobility group AT-hook 1a
chr1_+_54865552 0.38 ENSDART00000145381
si:ch211-196h16.5
chr14_+_16036139 0.38 ENSDART00000190733
PRELI domain containing 1a
chr10_+_24692076 0.38 ENSDART00000181600
transmembrane phosphatase with tensin homology
chr14_+_23717165 0.38 ENSDART00000006373
Nedd4 family interacting protein 1
chr19_-_18418763 0.37 ENSDART00000167271
zgc:112966
chr12_+_27243059 0.36 ENSDART00000066269
ADP-ribosylation factor-like 4D
chr21_+_12056934 0.36 ENSDART00000125380
zgc:162344
chr18_+_14477740 0.36 ENSDART00000146472
potassium voltage-gated channel, subfamily G, member 4a
chr13_+_8677166 0.36 ENSDART00000181016
ENSDART00000135028
PROP paired-like homeobox 1
chr17_-_36929332 0.35 ENSDART00000183454
dihydropyrimidinase-like 5a
chr12_-_17479078 0.34 ENSDART00000079115
3'-phosphoadenosine 5'-phosphosulfate synthase 2b
chr22_+_1440702 0.34 ENSDART00000165677
si:dkeyp-53d3.3
chr8_+_39619087 0.34 ENSDART00000134822
musashi RNA-binding protein 1
chr5_-_31856681 0.33 ENSDART00000187817
protein kinase N3
chr20_-_46467280 0.33 ENSDART00000060702
regulator of microtubule dynamics 3
chr25_+_20081553 0.33 ENSDART00000174684
troponin I4b, tandem duplicate 1
chr23_-_27857051 0.33 ENSDART00000043462
ENSDART00000137861
activin A receptor like type 1
chr20_+_9128256 0.33 ENSDART00000163883
ENSDART00000183072
ENSDART00000187276
bisphosphate nucleotidase 1
chr11_+_14280598 0.33 ENSDART00000163033
si:ch211-262i1.3
chr24_-_11076400 0.33 ENSDART00000003195
charged multivesicular body protein 4C
chr8_-_32385989 0.31 ENSDART00000143716
ENSDART00000098850
lipase, endothelial
chr22_-_10050856 0.31 ENSDART00000144811
zgc:174564
chr13_+_23897975 0.30 ENSDART00000002244
splicing factor 3b, subunit 5
chr4_-_28958601 0.30 ENSDART00000111294
zgc:174315
chr2_+_36939749 0.30 ENSDART00000005382
growth arrest and DNA-damage-inducible, beta b
chr17_-_32863250 0.30 ENSDART00000167292
prospero homeobox 1a
chr17_-_20228610 0.30 ENSDART00000125758
early B cell factor 3b
chr14_-_38828057 0.29 ENSDART00000186088
spindle apparatus coiled-coil protein 1
chr7_+_31145386 0.29 ENSDART00000075407
ENSDART00000169462
family with sequence similarity 189, member A1
chr7_-_26125092 0.29 ENSDART00000079364
small nuclear RNA activating complex, polypeptide 2
chr23_-_36446307 0.29 ENSDART00000136623
zgc:174906
chr22_-_10570749 0.29 ENSDART00000140736
si:dkey-42i9.6
chr18_-_33254039 0.28 ENSDART00000099130
si:ch211-229c8.4
chr22_+_38914983 0.28 ENSDART00000085701
SUMO1/sentrin specific peptidase 5
chr21_-_36453594 0.28 ENSDART00000193176
CCR4-NOT transcription complex, subunit 8
chr3_-_41715690 0.27 ENSDART00000184703

chr15_-_36533322 0.27 ENSDART00000156466
ENSDART00000121755
si:dkey-262k9.4
chr7_-_40145097 0.27 ENSDART00000173634
WD repeat domain 60
chr17_+_53292215 0.27 ENSDART00000170686
si:ch1073-416d2.3
chr20_-_39391833 0.27 ENSDART00000135149
si:dkey-217m5.8
chr5_-_20446082 0.26 ENSDART00000051607
si:ch211-191d15.2
chr12_+_19958845 0.26 ENSDART00000193248
excision repair cross-complementation group 4
chr21_+_22878834 0.26 ENSDART00000065562
PCF11 cleavage and polyadenylation factor subunit
chr17_-_6599484 0.26 ENSDART00000156927
si:ch211-189e2.2
chr25_-_29134654 0.25 ENSDART00000067066
poly (ADP-ribose) polymerase family, member 6b
chr8_+_43852743 0.25 ENSDART00000186485

chr1_-_35695614 0.25 ENSDART00000133813
ENSDART00000145291
ENSDART00000176451
si:dkey-27h10.2
chr8_-_49172418 0.25 ENSDART00000142437
ENSDART00000036157
FK506 binding protein 1Aa
chr16_+_54209504 0.25 ENSDART00000020033
X-ray repair complementing defective repair in Chinese hamster cells 1
chr24_-_26485098 0.25 ENSDART00000135496
ENSDART00000009609
ENSDART00000133782
ENSDART00000141029
ENSDART00000113739
eukaryotic translation initiation factor 5A
chr2_-_51512294 0.24 ENSDART00000185287
si:ch211-9d9.8
chr11_-_11791718 0.24 ENSDART00000180476
cell division cycle 6 homolog (S. cerevisiae)
chr23_-_7826849 0.24 ENSDART00000157612
myelin transcription factor 1b
chr13_-_42530656 0.23 ENSDART00000084327
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated
chr16_-_24703603 0.23 ENSDART00000131167
neuromast-expressed gpi-anchored lymphocyte antigen 6
chr9_+_21243985 0.23 ENSDART00000131586
si:rp71-68n21.12
chr16_+_25074029 0.22 ENSDART00000155465
si:dkeyp-84f3.9
chr21_-_26071142 0.22 ENSDART00000004740
RAB34, member RAS oncogene family b
chr12_-_33770299 0.22 ENSDART00000189849
lethal giant larvae homolog 2 (Drosophila)
chr19_-_11949996 0.22 ENSDART00000163478
ENSDART00000167299
cleavage and polyadenylation specific factor 1
chr16_-_40373836 0.22 ENSDART00000134498
si:dkey-242e21.3
chr7_-_59047720 0.22 ENSDART00000184831

chr22_-_13857729 0.22 ENSDART00000177971
S100 calcium binding protein, beta (neural)
chr9_-_48036 0.21 ENSDART00000165230
ENSDART00000171335
mitogen-activated protein kinase kinase kinase kinase 4
chr19_-_7420867 0.21 ENSDART00000081741
RAB25, member RAS oncogene family a
chr16_-_29690188 0.21 ENSDART00000132351
ENSDART00000004284
sodium channel modifier 1
chr6_+_12968101 0.20 ENSDART00000013781
minichromosome maintenance complex component 6
chr19_+_13410903 0.20 ENSDART00000165033
ENSDART00000168672
serine/arginine-rich splicing factor 4
chr20_+_35445462 0.20 ENSDART00000124497
tudor domain containing 6
chr21_-_2955181 0.19 ENSDART00000158991
ENSDART00000174052
zinc finger protein 971
chr12_-_16084835 0.19 ENSDART00000090881
potassium voltage-gated channel, subfamily J, member 19b
chr7_-_27696958 0.19 ENSDART00000173470
calcitonin/calcitonin-related polypeptide, alpha
chr1_+_46405294 0.19 ENSDART00000143228
tubulin, gamma complex associated protein 3
chr14_-_38873095 0.19 ENSDART00000047050
ENSDART00000173285
ENSDART00000147521
glutathione reductase
chr25_-_12998202 0.18 ENSDART00000171661
chemokine (C-C motif) ligand 39, duplicate 3
chr5_-_11905920 0.18 ENSDART00000114378
F-box and WD repeat domain containing 8
chr24_-_16980337 0.17 ENSDART00000183812
kelch-like family member 15
chr8_-_46486009 0.17 ENSDART00000140431
sulfotransferase family 1, cytosolic sulfotransferase 9
chr7_+_52178109 0.16 ENSDART00000174099
katanin p80 (WD repeat containing) subunit B 1
chr11_-_16093018 0.16 ENSDART00000139309
ENSDART00000139819
si:dkey-205k8.5
chr15_-_37779978 0.16 ENSDART00000157202
si:dkey-42l23.3
chr4_+_11723852 0.16 ENSDART00000028820
muskelin 1, intracellular mediator containing kelch motifs
chr16_-_24703855 0.15 ENSDART00000182422
neuromast-expressed gpi-anchored lymphocyte antigen 6
chr1_+_55476002 0.15 ENSDART00000152356
si:dkey-9c18.3
chr5_-_57528943 0.15 ENSDART00000130320
phosphatidylserine decarboxylase
chr11_+_583725 0.15 ENSDART00000189415
MKRN2 opposite strand, tandem duplicate 2
chr2_+_6963296 0.15 ENSDART00000147146
discoidin domain receptor tyrosine kinase 2b
chr19_+_43715911 0.15 ENSDART00000006344
CAP, adenylate cyclase-associated protein 1 (yeast)
chr5_-_66028371 0.15 ENSDART00000183012
NOTCH regulated ankyrin repeat protein b
chr11_+_36665359 0.15 ENSDART00000166144
si:ch211-11c3.9
chr19_+_47311020 0.15 ENSDART00000138295
exostoses (multiple) 1c
chr16_+_26846495 0.14 ENSDART00000078124
tripartite motif containing 35-29
chr7_-_1965927 0.14 ENSDART00000053656
si:cabz01040626.2
chr4_-_14470071 0.14 ENSDART00000143773
plexin b2a
chr2_-_37134169 0.13 ENSDART00000146123
ENSDART00000146533
ENSDART00000040427
ELAV like RNA binding protein 1a
chr20_+_88168 0.13 ENSDART00000149283
zgc:112001
chr4_-_25796848 0.13 ENSDART00000122881
transmembrane and coiled-coil domain family 3
chr5_-_20879527 0.13 ENSDART00000134697
phosphoinositide-3-kinase interacting protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of sox14+sox14-1+sox21a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.1 GO:0061621 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 2.2 GO:0006833 water transport(GO:0006833)
0.2 1.1 GO:0003210 cardiac atrium formation(GO:0003210)
0.2 0.6 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.2 0.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 0.5 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.2 0.5 GO:1990120 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833) messenger ribonucleoprotein complex assembly(GO:1990120)
0.2 0.5 GO:1990403 embryonic brain development(GO:1990403)
0.2 0.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.4 GO:0002902 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878) regulation of lymphocyte apoptotic process(GO:0070228)
0.1 0.4 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.1 0.5 GO:0018377 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.1 0.7 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.1 1.3 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 0.3 GO:0000103 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 0.9 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 0.9 GO:0071450 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 0.3 GO:1901255 nucleotide-excision repair involved in interstrand cross-link repair(GO:1901255)
0.1 0.3 GO:0034405 response to fluid shear stress(GO:0034405)
0.1 1.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.4 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.1 1.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.2 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.4 GO:0000730 DNA recombinase assembly(GO:0000730)
0.1 7.3 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 0.5 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.1 2.2 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 0.6 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.2 GO:0000012 single strand break repair(GO:0000012)
0.0 0.8 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.2 GO:0010719 photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 0.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0090219 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.0 0.3 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.5 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.1 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.3 GO:0034501 mitotic metaphase plate congression(GO:0007080) protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.1 GO:0070166 enamel mineralization(GO:0070166)
0.0 1.0 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.3 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.2 GO:0045905 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.5 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.0 0.1 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.3 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.2 GO:0030719 P granule organization(GO:0030719)
0.0 0.1 GO:0006844 acyl carnitine transport(GO:0006844)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0014909 smooth muscle cell migration(GO:0014909)
0.0 0.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.5 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.7 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.2 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.3 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.4 GO:0021984 adenohypophysis development(GO:0021984)
0.0 1.5 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.8 GO:0043113 receptor clustering(GO:0043113)
0.0 0.3 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.0 0.3 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0 0.5 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.8 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.3 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.3 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.9 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.4 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 0.1 GO:0030825 regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 0.5 GO:0042382 paraspeckles(GO:0042382)
0.1 1.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.4 GO:0033065 Rad51C-XRCC3 complex(GO:0033065)
0.1 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.2 GO:0033391 chromatoid body(GO:0033391)
0.1 0.3 GO:0070724 BMP receptor complex(GO:0070724)
0.1 0.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 0.2 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.1 0.8 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 0.5 GO:0032021 NELF complex(GO:0032021)
0.1 0.2 GO:0008352 katanin complex(GO:0008352)
0.1 0.9 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.6 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.5 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.5 GO:0005581 collagen trimer(GO:0005581)
0.0 1.9 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.2 2.2 GO:0015250 water channel activity(GO:0015250)
0.2 1.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.2 1.3 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.4 GO:0043621 protein self-association(GO:0043621)
0.1 0.4 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 0.5 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.1 0.9 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.4 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.1 2.1 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.1 0.5 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.1 0.3 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 1.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 7.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.4 GO:0050699 WW domain binding(GO:0050699)
0.1 0.2 GO:0031716 calcitonin receptor binding(GO:0031716)
0.1 0.4 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 1.2 GO:0070122 isopeptidase activity(GO:0070122)
0.1 0.3 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.1 0.4 GO:0035173 histone kinase activity(GO:0035173)
0.1 0.4 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.2 GO:0044548 S100 protein binding(GO:0044548)
0.1 1.0 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.8 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.8 GO:0008252 nucleotidase activity(GO:0008252)
0.0 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.5 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 1.0 GO:0003823 antigen binding(GO:0003823)
0.0 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.6 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.3 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.5 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.1 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 1.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 1.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.2 PID AURORA A PATHWAY Aurora A signaling
0.0 1.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.8 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.9 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.2 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 0.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 1.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.2 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.5 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.8 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.1 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.4 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.4 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination