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PRJEB1986: zebrafish developmental stages transcriptome

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Results for sox11a+sox11b

Z-value: 1.00

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Transcription factors associated with sox11a+sox11b

Gene Symbol Gene ID Gene Info
ENSDARG00000077811 SRY-box transcription factor 11a
ENSDARG00000095743 SRY-box transcription factor 11b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox11bdr11_v1_chr20_-_30035326_30035326-0.427.7e-02Click!
sox11adr11_v1_chr17_-_35881841_35881841-0.399.7e-02Click!

Activity profile of sox11a+sox11b motif

Sorted Z-values of sox11a+sox11b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_22240052 6.16 ENSDART00000111109
crystallin, gamma M2d9
chr5_-_26118855 5.44 ENSDART00000009028
elastase 3 like
chr3_-_61205711 4.22 ENSDART00000055062
parvalbumin 1
chr19_-_21832441 3.23 ENSDART00000151272
ENSDART00000151442
ENSDART00000150168
ENSDART00000148797
ENSDART00000128196
ENSDART00000149259
ENSDART00000052556
ENSDART00000149658
ENSDART00000149639
ENSDART00000148424
myelin basic protein a
chr18_+_25653599 3.05 ENSDART00000007856
FK506 binding protein 16
chr1_-_20928772 3.01 ENSDART00000078277
methylsterol monooxygenase 1
chr21_+_11401247 2.86 ENSDART00000143952
carboxyl ester lipase, tandem duplicate 1
chr13_+_24755049 2.81 ENSDART00000134102
collagen, type XVII, alpha 1b
chr20_+_9128829 2.63 ENSDART00000064144
ENSDART00000137450
bisphosphate nucleotidase 1
chr2_+_52232630 2.57 ENSDART00000006216
phospholipid phosphatase 2a
chr22_+_7439186 2.50 ENSDART00000190667
zgc:92041
chr19_+_37509638 2.44 ENSDART00000139999
si:ch211-250g4.3
chr16_-_23346095 2.30 ENSDART00000160546
si:dkey-247k7.2
chr1_-_54765262 2.29 ENSDART00000150362
si:ch211-197k17.3
chr20_+_9128256 2.20 ENSDART00000163883
ENSDART00000183072
ENSDART00000187276
bisphosphate nucleotidase 1
chr16_-_24598042 2.20 ENSDART00000156407
ENSDART00000154072
si:dkey-56f14.4
chr12_-_21834611 2.19 ENSDART00000179553
thyroid hormone receptor alpha b
chr11_+_30513656 2.18 ENSDART00000008594
transmembrane protein 178
chr2_-_32643738 2.17 ENSDART00000112452
si:dkeyp-73d8.9
chr8_+_24861264 2.15 ENSDART00000099607
solute carrier family 6 (neutral amino acid transporter), member 17
chr2_+_24177006 2.15 ENSDART00000132582
microtubule associated protein 4 like
chr1_-_14234076 2.11 ENSDART00000040049
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr5_-_32308526 2.10 ENSDART00000193758
myosin, heavy polypeptide 1.1, skeletal muscle
chr20_+_41664350 2.03 ENSDART00000186247
family with sequence similarity 184, member A
chr10_+_2587234 2.00 ENSDART00000126937
wu:fb59d01
chr17_+_33340675 1.97 ENSDART00000184396
ENSDART00000077553
xanthine dehydrogenase
chr16_-_52540056 1.96 ENSDART00000188304

chr2_+_24177190 1.90 ENSDART00000099546
microtubule associated protein 4 like
chr5_-_38342992 1.82 ENSDART00000140337
misshapen-like kinase 1
chr13_+_13693722 1.79 ENSDART00000110509
si:ch211-194c3.5
chr17_-_39185336 1.78 ENSDART00000050534
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr25_+_35056619 1.78 ENSDART00000154389
histone cluster 1 H4 family member j
chr23_+_40460333 1.75 ENSDART00000184658
SOGA family member 3b
chr8_-_14050758 1.70 ENSDART00000133922
ATPase plasma membrane Ca2+ transporting 3a
chr21_-_41305748 1.68 ENSDART00000170457
neuronal vesicle trafficking associated 2
chr11_+_39672874 1.64 ENSDART00000046663
ENSDART00000157659
calmodulin binding transcription activator 1b
chr18_+_3579829 1.60 ENSDART00000158763
ENSDART00000182850
ENSDART00000162754
ENSDART00000178789
ENSDART00000172656
leucine-rich repeats and calponin homology (CH) domain containing 3
chr13_-_11644806 1.60 ENSDART00000169953
dynactin 1b
chr1_-_22512063 1.57 ENSDART00000031546
ENSDART00000190987
cholinergic receptor, nicotinic, alpha 6
chr23_-_17657348 1.54 ENSDART00000054736
basic helix-loop-helix family, member e23
chr8_-_10045043 1.53 ENSDART00000081917
si:dkey-8e10.3
chr10_+_41668483 1.49 ENSDART00000127073
leucine rich repeat containing 75Bb
chr3_+_19299309 1.47 ENSDART00000046297
ENSDART00000146955
low density lipoprotein receptor a
chr25_+_14087045 1.46 ENSDART00000155770
actin, alpha, cardiac muscle 1c
chr6_-_57539141 1.46 ENSDART00000156967
itchy E3 ubiquitin protein ligase a
chr8_-_5220125 1.45 ENSDART00000035676
BCL2 interacting protein 3 like a
chr14_-_2187202 1.36 ENSDART00000160205
protocadherin 2 alpha b 12
chr20_+_50852356 1.34 ENSDART00000167517
ENSDART00000168396
gephyrin b
chr2_+_28672152 1.33 ENSDART00000157410
ENSDART00000169614
NAD synthetase 1
chr20_-_26039841 1.31 ENSDART00000179929
si:dkey-12h9.6
chr23_+_11669109 1.29 ENSDART00000091416
contactin 3a, tandem duplicate 1
chr14_+_4151379 1.29 ENSDART00000160431
dehydrogenase/reductase (SDR family) member 13 like 1
chr5_+_26795465 1.26 ENSDART00000053001
transcobalamin II
chr3_+_22270463 1.25 ENSDART00000104004
sodium channel, voltage-gated, type IV, alpha, b
chr9_-_18568927 1.24 ENSDART00000084668
ecto-NOX disulfide-thiol exchanger 1
chr20_-_47731768 1.22 ENSDART00000031167
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr16_-_22006996 1.21 ENSDART00000116114
si:dkey-71b5.7
chr17_-_47090440 1.18 ENSDART00000163542

chr13_-_40499296 1.15 ENSDART00000158338
Danio rerio cyclin and CBS domain divalent metal cation transport mediator 1 (cnnm1), mRNA.
chr2_-_37889111 1.15 ENSDART00000168939
ENSDART00000098529
mannose binding lectin 2
chr20_+_50115335 1.13 ENSDART00000031139
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4b
chr9_+_19039608 1.13 ENSDART00000055866
charged multivesicular body protein 2Ba
chr6_+_54538948 1.12 ENSDART00000149270
tubby like protein 1b
chr20_-_35706379 1.08 ENSDART00000152847
si:dkey-30j22.1
chr5_-_35301800 1.06 ENSDART00000085142
microtubule-associated protein 1B
chr17_-_48915427 1.04 ENSDART00000054781
galectin 8b
chr9_+_17984358 1.02 ENSDART00000192399
A kinase (PRKA) anchor protein 11
chr11_+_30282141 1.01 ENSDART00000122756
si:dkey-163f14.6
chr21_+_26612777 0.98 ENSDART00000142667
estrogen-related receptor alpha
chr6_+_39812475 0.96 ENSDART00000067063
complement component 1, q subcomponent-like 4b
chr16_-_33001153 0.95 ENSDART00000147941
malic enzyme 1, NADP(+)-dependent, cytosolic
chr2_-_1569250 0.94 ENSDART00000167202
Dab, reelin signal transducer, homolog 1b (Drosophila)
chr2_-_26509057 0.92 ENSDART00000139169
ENSDART00000181777
bestrophin 4
chr9_+_38883388 0.88 ENSDART00000135902
microtubule-associated protein 2
chr20_+_54383838 0.88 ENSDART00000157737
leucine rich repeat and fibronectin type III domain containing 5b
chr15_-_2841677 0.86 ENSDART00000026145
ENSDART00000180290
angiomotin like 1
chr24_+_22056386 0.86 ENSDART00000132390
ankyrin repeat domain 33ba
chr21_-_21530868 0.86 ENSDART00000174231
odorant receptor, family H, subfamily 133, member 9
chr22_+_7462997 0.85 ENSDART00000106082
zgc:112368
chr20_+_37295006 0.84 ENSDART00000153137
connexin 23
chr5_+_37069605 0.83 ENSDART00000161977
si:dkeyp-110c7.4
chr7_+_54642005 0.83 ENSDART00000171864
fibroblast growth factor 19
chr20_-_8304271 0.83 ENSDART00000179057
Dab, reelin signal transducer, homolog 1a (Drosophila)
chr18_-_25177230 0.83 ENSDART00000013363
solute carrier organic anion transporter family, member 3A1
chr6_-_1768724 0.82 ENSDART00000162488
ENSDART00000163613
zgc:158417
chr10_+_38806719 0.81 ENSDART00000184416
Down syndrome cell adhesion molecule a
chr6_-_59271436 0.80 ENSDART00000174588
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2b
chr12_+_32323098 0.80 ENSDART00000188722
si:ch211-277e21.2
chr24_-_41220538 0.80 ENSDART00000150207
activin A receptor type 2Ba
chr23_+_4226341 0.80 ENSDART00000012445
zgc:113278
chr15_-_40267485 0.78 ENSDART00000152253
potassium inwardly-rectifying channel, subfamily J, member 13
chr19_+_2279051 0.78 ENSDART00000182103
integrin, beta 8
chr19_+_32401278 0.77 ENSDART00000184353
ataxin 1a
chr18_-_3527686 0.75 ENSDART00000169049
calpain 5a
chr11_-_25734417 0.75 ENSDART00000103570
bromodomain and PHD finger containing, 3a
chr17_-_43558494 0.74 ENSDART00000103830
5'-nucleotidase, cytosolic IAb
chr11_-_25733910 0.73 ENSDART00000171935
bromodomain and PHD finger containing, 3a
chr14_+_29200772 0.72 ENSDART00000166608
si:dkey-34l15.2
chr18_-_43884044 0.71 ENSDART00000087382
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr15_-_15357178 0.71 ENSDART00000106120
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2
chr11_+_41243094 0.70 ENSDART00000191782
ENSDART00000169817
ENSDART00000162157
paired box 7a
chr12_-_44010532 0.69 ENSDART00000183875
si:ch211-182p11.1
chr6_-_59271270 0.69 ENSDART00000126870
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2b
chr17_+_47090497 0.68 ENSDART00000169038
ENSDART00000159292
zgc:103755
chr10_+_21650828 0.67 ENSDART00000160754
protocadherin 1 gamma 1
chr11_-_1409236 0.67 ENSDART00000121537
si:ch211-266k22.6
chr20_-_31067306 0.66 ENSDART00000014163
fibronectin type III domain containing 1
chr3_+_12861158 0.64 ENSDART00000171237
potassium inwardly-rectifying channel, subfamily J, member 2b
chr1_-_36152131 0.64 ENSDART00000182113
ENSDART00000182904
zinc finger protein 827
chr1_+_10003193 0.64 ENSDART00000162675
tripartite motif containing 2b
chr22_+_3156386 0.63 ENSDART00000161212
ribosomal protein L36
chr4_-_42391176 0.63 ENSDART00000189739
si:ch211-59d8.2
chr7_+_19762595 0.62 ENSDART00000130347
si:dkey-9k7.3
chr25_+_35058088 0.61 ENSDART00000156838
zgc:112234
chr24_+_30521619 0.61 ENSDART00000162903
dihydropyrimidine dehydrogenase a, tandem duplicate 3
chr9_+_24008879 0.61 ENSDART00000190419
ENSDART00000191843
ENSDART00000148226
melanophilin b
chr13_-_1349922 0.60 ENSDART00000140970
si:ch73-52p7.1
chr22_-_35961365 0.60 ENSDART00000188434

chr10_-_7857494 0.60 ENSDART00000143215
inositol polyphosphate-5-phosphatase Ja
chr8_-_1838315 0.58 ENSDART00000114476
ENSDART00000140077
phosphatidylinositol 4-kinase, catalytic, alpha b
chr5_+_1983495 0.56 ENSDART00000179860

chr2_+_9061885 0.54 ENSDART00000028906
phosphatidylinositol glycan anchor biosynthesis, class K
chr3_+_26267725 0.54 ENSDART00000131288
ArfGAP with dual PH domains 2
chr11_-_891674 0.53 ENSDART00000172904
ATG7 autophagy related 7 homolog (S. cerevisiae)
chr1_-_23596391 0.53 ENSDART00000155184
ligand dependent nuclear receptor corepressor-like
chr11_+_23760470 0.52 ENSDART00000175688
ENSDART00000121874
ENSDART00000086720
neurofascin homolog (chicken) a
chr1_+_16397063 0.52 ENSDART00000159794
mitochondrial calcium uptake family, member 3a
chr22_+_37902976 0.49 ENSDART00000169327
potassium voltage-gated channel, subfamily H (eag-related), member 1a
chr7_-_51727760 0.48 ENSDART00000174180
histone deacetylase 8
chr3_-_8399774 0.47 ENSDART00000190238
ENSDART00000113140
ENSDART00000132949
RNA binding fox-1 homolog 3b
chr18_-_16392229 0.46 ENSDART00000189031
mgat4 family, member C
chr24_-_26302375 0.46 ENSDART00000130696
COP9 signalosome subunit 9
chr15_-_38177768 0.46 ENSDART00000152404
si:dkey-24p1.7
chr2_+_904362 0.46 ENSDART00000024967
receptor (TNFRSF)-interacting serine-threonine kinase 1, like
chr21_-_41025340 0.45 ENSDART00000148231
PLAC8-like 1
chr19_-_31402429 0.45 ENSDART00000137292
transmembrane protein 106Bb
chr15_-_38186537 0.41 ENSDART00000012872
cholinergic receptor, nicotinic, alpha 10a
chr16_+_36768674 0.41 ENSDART00000169208
ENSDART00000180470
si:ch73-215d9.1
chr19_-_47456787 0.40 ENSDART00000168792
transcription factor AP-2 epsilon
chr5_-_57528943 0.40 ENSDART00000130320
phosphatidylserine decarboxylase
chr25_-_29087925 0.40 ENSDART00000171758
ribonuclease P and MRP subunit p25, a
chr10_+_6884123 0.40 ENSDART00000149095
ENSDART00000148772
ENSDART00000149334
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr2_-_2451181 0.40 ENSDART00000101033
parathyroid hormone 1 receptor a
chr11_-_16093018 0.39 ENSDART00000139309
ENSDART00000139819
si:dkey-205k8.5
chr5_-_66301142 0.39 ENSDART00000067541
prolactin receptor b
chr2_-_37532772 0.38 ENSDART00000133951
rho/rac guanine nucleotide exchange factor (GEF) 18a
chr16_+_6957582 0.38 ENSDART00000111308
ENSDART00000187541
ENSDART00000149987
Bardet-Biedl syndrome 9
chr5_-_3118346 0.38 ENSDART00000167554
heat shock transcription factor family member 5
chr1_-_21297748 0.36 ENSDART00000142109
neuropeptide Y receptor Y1
chr5_-_13251907 0.35 ENSDART00000176774
ENSDART00000030553
DNA topoisomerase III beta
chr1_-_19079957 0.35 ENSDART00000141795
paired-like homeobox 2ba
chr21_-_30254185 0.35 ENSDART00000101054
DnaJ (Hsp40) homolog, subfamily C, member 18
chr16_-_44878245 0.35 ENSDART00000154391
ENSDART00000154925
ENSDART00000154697
Rho GTPase activating protein 33
chr16_+_54263921 0.34 ENSDART00000002856
dopamine receptor D2 like
chr7_-_58729894 0.34 ENSDART00000149347
coiled-coil-helix-coiled-coil-helix domain containing 7
chr14_+_45970033 0.34 ENSDART00000047716
fermitin family member 3b
chr23_+_38953545 0.34 ENSDART00000184621
ATPase phospholipid transporting 9A (putative)
chr23_-_22650992 0.33 ENSDART00000079007
carbonic anhydrase VI
chr1_+_46948010 0.33 ENSDART00000132843
si:dkey-22n8.2
chrM_+_6425 0.31 ENSDART00000093606
cytochrome c oxidase I, mitochondrial
chr19_+_26718074 0.31 ENSDART00000134455
zgc:100906
chr6_-_31336317 0.31 ENSDART00000193927
DnaJ (Hsp40) homolog, subfamily C, member 6
chr6_+_39098397 0.30 ENSDART00000003716
ENSDART00000188655
protease, serine, 60.2
chr16_+_18535618 0.30 ENSDART00000021596
retinoid x receptor, beta b
chrM_+_12897 0.30 ENSDART00000093622
NADH dehydrogenase 5, mitochondrial
chr23_+_23022790 0.30 ENSDART00000189843
sterile alpha motif domain containing 11
chr6_+_42820228 0.29 ENSDART00000185413
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa
chr12_-_18408566 0.29 ENSDART00000078767
ENSDART00000152748
target of myb1 like 2 membrane trafficking protein
chr10_-_41907213 0.27 ENSDART00000167004
lysine (K)-specific demethylase 2Bb
chr22_+_3238474 0.27 ENSDART00000157954
si:ch1073-178p5.3
chr7_-_40145097 0.27 ENSDART00000173634
WD repeat domain 60
chr16_+_40217043 0.27 ENSDART00000191128

chr2_+_26240631 0.26 ENSDART00000129895
paralemmin 1b
chr22_-_6361178 0.26 ENSDART00000150147
zgc:113298
chr15_-_20949692 0.25 ENSDART00000185548
tubulin folding cofactor E-like a
chr5_-_41841892 0.25 ENSDART00000167089
si:dkey-65b12.6
chr20_+_19793620 0.25 ENSDART00000136317
cholinergic receptor, nicotinic, alpha 2b (neuronal)
chr20_-_35012093 0.24 ENSDART00000062761
consortin, connexin sorting protein b
chr18_+_5547185 0.24 ENSDART00000193977
nicotinamide nucleotide transhydrogenase 2
chr10_-_39321367 0.23 ENSDART00000129647
somatolactin beta
chr15_-_45510977 0.22 ENSDART00000090596
fibroblast growth factor 12b
chr4_-_18635005 0.22 ENSDART00000125361
peroxisome proliferator-activated receptor alpha a
chr12_+_46696867 0.21 ENSDART00000152928
ENSDART00000153445
ENSDART00000123357
ENSDART00000152880
ENSDART00000123834
ENSDART00000174765
ENSDART00000189923
exocyst complex component 7
chr21_-_40317035 0.21 ENSDART00000143648
ENSDART00000013359
odorant receptor, family B, subfamily 101, member 1
chr16_-_17056630 0.19 ENSDART00000138715
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr12_-_20665164 0.19 ENSDART00000105352
gastric inhibitory polypeptide
chr19_-_1920613 0.19 ENSDART00000186176
si:ch211-149a19.3
chr8_-_36140405 0.18 ENSDART00000182806

chr11_+_36355348 0.17 ENSDART00000145427
synaptophysin-like 2a
chr15_+_41932853 0.17 ENSDART00000183581
ENSDART00000157807
si:ch211-191a16.2
chr23_-_6865946 0.16 ENSDART00000056426
finTRIM family, member 58
chr8_-_38105053 0.14 ENSDART00000131546
adhesion G protein-coupled receptor A2
chr13_-_45201300 0.14 ENSDART00000074750
ENSDART00000180265
runt-related transcription factor 3
chr6_+_4229360 0.14 ENSDART00000191347
ENSDART00000130642

chr16_-_15988320 0.13 ENSDART00000160883

chr15_-_14467394 0.13 ENSDART00000191944
numb homolog (Drosophila)-like
chr8_+_8671229 0.12 ENSDART00000131963
ubiquitin specific peptidase 11
chr9_-_5318873 0.12 ENSDART00000129308
activin A receptor type 1C
chr20_+_16703050 0.11 ENSDART00000005244
potassium channel, subfamily K, member 13b
chr12_-_37734973 0.10 ENSDART00000140353
sidekick cell adhesion molecule 2b

Network of associatons between targets according to the STRING database.

First level regulatory network of sox11a+sox11b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.7 2.1 GO:0015824 proline transport(GO:0015824)
0.7 2.0 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.4 1.3 GO:0018315 establishment of synaptic specificity at neuromuscular junction(GO:0007529) molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.4 1.3 GO:0015889 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
0.3 1.3 GO:0023041 neuronal signal transduction(GO:0023041)
0.3 2.9 GO:0097090 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.2 1.2 GO:0007624 ultradian rhythm(GO:0007624)
0.2 5.4 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.2 1.8 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.2 2.2 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.2 0.8 GO:0051876 pigment granule dispersal(GO:0051876)
0.2 1.4 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.2 0.5 GO:2000434 regulation of protein neddylation(GO:2000434)
0.2 0.6 GO:0015990 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.1 1.5 GO:0034381 plasma lipoprotein particle clearance(GO:0034381)
0.1 0.7 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.1 0.6 GO:0019860 uracil catabolic process(GO:0006212) beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483) uracil metabolic process(GO:0019860) 'de novo' UMP biosynthetic process(GO:0044205)
0.1 0.7 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.1 0.3 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631) regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.1 1.5 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 0.4 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 1.3 GO:0009435 NAD biosynthetic process(GO:0009435)
0.1 0.9 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.7 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.2 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 0.8 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 0.5 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 1.1 GO:0001840 neural plate development(GO:0001840)
0.1 2.1 GO:0001757 somite specification(GO:0001757)
0.1 1.3 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 2.1 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 3.0 GO:0016126 sterol biosynthetic process(GO:0016126)
0.1 1.3 GO:0042574 retinal metabolic process(GO:0042574)
0.1 1.8 GO:0048570 notochord morphogenesis(GO:0048570)
0.1 1.6 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 0.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.5 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 0.2 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.7 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 7.0 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 1.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.8 GO:1901571 icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571)
0.0 0.5 GO:0021576 hindbrain formation(GO:0021576)
0.0 1.0 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0022009 central nervous system vasculogenesis(GO:0022009)
0.0 0.2 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304)
0.0 0.4 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 1.5 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 1.8 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 2.0 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 2.6 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.8 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.2 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.3 GO:0051967 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.2 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 1.0 GO:0061035 regulation of cartilage development(GO:0061035)
0.0 0.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 1.1 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.1 GO:0002676 granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
0.0 0.2 GO:0035094 response to nicotine(GO:0035094)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.5 GO:0003171 atrioventricular valve development(GO:0003171)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.5 GO:0019226 transmission of nerve impulse(GO:0019226)
0.0 0.8 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 1.8 GO:0010506 regulation of autophagy(GO:0010506)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.4 GO:0001843 neural tube closure(GO:0001843)
0.0 2.8 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 1.2 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.3 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 2.1 GO:0042391 regulation of membrane potential(GO:0042391)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.2 GO:0043209 myelin sheath(GO:0043209)
0.1 1.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.5 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 2.3 GO:0035371 microtubule plus-end(GO:0035371)
0.1 1.5 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 1.1 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.4 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.8 GO:0048179 activin receptor complex(GO:0048179)
0.1 1.3 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 1.3 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.4 GO:0034464 BBSome(GO:0034464)
0.0 0.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.5 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 2.0 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.1 GO:0016459 myosin complex(GO:0016459)
0.0 0.8 GO:0008305 integrin complex(GO:0008305)
0.0 0.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 3.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 4.9 GO:0005874 microtubule(GO:0005874)
0.0 6.0 GO:0009986 cell surface(GO:0009986)
0.0 1.1 GO:0005581 collagen trimer(GO:0005581)
0.0 12.8 GO:0005615 extracellular space(GO:0005615)
0.0 0.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0004771 sterol esterase activity(GO:0004771)
0.4 1.3 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.4 3.0 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.4 1.5 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.2 5.6 GO:0008252 nucleotidase activity(GO:0008252)
0.2 0.9 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.2 2.0 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.2 3.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 1.3 GO:0031419 cobalamin binding(GO:0031419)
0.2 0.6 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.1 1.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 1.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 1.1 GO:0004359 glutaminase activity(GO:0004359)
0.1 1.7 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.5 GO:0019778 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 1.5 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 2.6 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.4 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 2.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.6 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.2 GO:0070186 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
0.1 0.6 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1 6.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 2.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.8 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 2.1 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 1.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.2 GO:0071253 connexin binding(GO:0071253)
0.1 3.1 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 0.2 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 1.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 0.5 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.8 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 2.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.8 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.2 GO:0031769 glucagon receptor binding(GO:0031769)
0.0 0.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.5 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.8 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 1.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 5.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.1 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 2.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.4 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 6.0 GO:0008017 microtubule binding(GO:0008017)
0.0 0.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 2.1 GO:0003774 motor activity(GO:0003774)
0.0 0.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.6 GO:0017022 myosin binding(GO:0017022)
0.0 1.1 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 0.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 1.1 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.9 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.8 PID FGF PATHWAY FGF signaling pathway
0.0 2.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.4 2.0 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.2 1.6 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.8 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 3.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.8 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 0.8 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis