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PRJEB1986: zebrafish developmental stages transcriptome

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Results for sox10

Z-value: 0.92

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Transcription factors associated with sox10

Gene Symbol Gene ID Gene Info
ENSDARG00000077467 SRY-box transcription factor 10

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox10dr11_v1_chr3_+_1492174_14921740.371.2e-01Click!

Activity profile of sox10 motif

Sorted Z-values of sox10 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr22_+_14098028 3.55 ENSDART00000018432
hatching enzyme 1, tandem dupliate 2
chr13_+_33651416 3.51 ENSDART00000180221

chr1_-_33645967 1.56 ENSDART00000192758
claudin g
chr14_+_16036139 1.54 ENSDART00000190733
PRELI domain containing 1a
chr23_+_36144487 1.51 ENSDART00000082473
homeobox C3a
chr5_-_61652254 1.44 ENSDART00000097364
draculin
chr6_+_45932276 1.38 ENSDART00000103491
retinol binding protein 7b, cellular
chr23_-_21471022 1.35 ENSDART00000104206
hairy-related 4, tandem duplicate 2
chr2_-_42960353 1.26 ENSDART00000098303
otoconin 90
chr22_-_10541372 1.25 ENSDART00000179708
si:dkey-42i9.4
chr11_+_3501669 1.21 ENSDART00000160808
pseudouridylate synthase-like 1
chr9_+_15893093 1.19 ENSDART00000099483
ENSDART00000134657
si:dkey-14o1.20
chr3_-_41535647 1.18 ENSDART00000153723
ENSDART00000154198
si:ch211-222n22.1
chr19_-_47570672 1.18 ENSDART00000112155
ribonucleotide reductase M2 polypeptide
chr19_-_18152407 1.18 ENSDART00000193264
ENSDART00000016135
nuclear factor, erythroid 2-like 3
chr3_-_16250527 1.16 ENSDART00000146699
ENSDART00000141181
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr14_+_25505468 1.13 ENSDART00000079016
THO complex 3
chr16_-_45917322 1.12 ENSDART00000060822
antifreeze protein type IV
chr8_+_39802506 1.11 ENSDART00000018862
HNF1 homeobox a
chr24_+_22485710 1.11 ENSDART00000146058
si:dkey-40h20.1
chr7_+_22688781 1.09 ENSDART00000173509
UDP glucuronosyltransferase 5 family, polypeptide G1
chr15_-_36365840 1.05 ENSDART00000192926
si:dkey-23k10.3
chr21_-_20342096 1.03 ENSDART00000065659
retinol binding protein 4, like
chr20_-_29498178 1.02 ENSDART00000152986
ENSDART00000027851
ENSDART00000152954
ribonucleotide reductase M2 polypeptide
chr5_-_20205075 1.02 ENSDART00000051611
D-amino-acid oxidase, tandem duplicate 3
chr6_-_43092175 1.00 ENSDART00000084389
leucine rich repeat neuronal 1
chr13_+_21677767 0.99 ENSDART00000165166
mitochondrial ribosome-associated GTPase 1
chr15_+_35691783 0.96 ENSDART00000183994

chr4_-_38877924 0.94 ENSDART00000177741
zinc finger protein 1127
chr19_-_17208728 0.93 ENSDART00000151228
stathmin 1a
chr15_-_3736149 0.93 ENSDART00000182986
lysophosphatidic acid receptor 6a
chr13_+_18321140 0.92 ENSDART00000180947
eukaryotic translation initiation factor 4E family member 1c
chr22_-_15587360 0.91 ENSDART00000142717
ENSDART00000138978
tropomyosin 4a
chr21_-_25741411 0.91 ENSDART00000101211
claudin h
chr6_-_54290227 0.90 ENSDART00000050483
SAM pointed domain containing ETS transcription factor
chr22_-_18546241 0.89 ENSDART00000105404
ENSDART00000105405
cold inducible RNA binding protein b
chr24_+_18714212 0.89 ENSDART00000171181
centrosome and spindle pole associated protein 1a
chr5_+_67662430 0.89 ENSDART00000137700
ENSDART00000142586
si:dkey-70b23.2
chr3_-_26184018 0.88 ENSDART00000191604
si:ch211-11k18.4
chr16_+_26732086 0.87 ENSDART00000138496
RAD54 homolog B (S. cerevisiae)
chr6_-_6993046 0.87 ENSDART00000053304
si:ch211-114n24.6
chr4_+_63088692 0.87 ENSDART00000168872
zgc:173714
chr7_+_24814866 0.86 ENSDART00000173581
si:ch211-226l4.6
chr22_-_10541712 0.86 ENSDART00000013933
si:dkey-42i9.4
chr3_-_31258459 0.85 ENSDART00000177928

chr14_+_989733 0.85 ENSDART00000161487
ENSDART00000127317
si:ch73-308l14.2
chr17_-_16422654 0.85 ENSDART00000150149
tyrosyl-DNA phosphodiesterase 1
chr7_-_38689562 0.85 ENSDART00000167209
apelin receptor 2
chr17_+_15535501 0.84 ENSDART00000002932
myristoylated alanine-rich protein kinase C substrate b
chr7_+_22982201 0.84 ENSDART00000134116
cyclin B3
chr18_-_37241080 0.83 ENSDART00000126421
ENSDART00000078064
SIX homeobox 9
chr4_+_25607743 0.83 ENSDART00000028297
acyl-CoA thioesterase 14
chr18_-_35407695 0.82 ENSDART00000191845
ENSDART00000141703
small nuclear ribonucleoprotein polypeptide A
chr19_+_43017931 0.81 ENSDART00000132213
sodium/potassium transporting ATPase interacting 1
chr16_-_32233463 0.81 ENSDART00000102016
calcium homeostasis modulator family member 6
chr23_-_30727596 0.81 ENSDART00000060193
THAP domain containing, apoptosis associated protein 3
chr18_-_25051846 0.79 ENSDART00000013082
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr25_+_14400704 0.78 ENSDART00000067235
cytokine induced apoptosis inhibitor 1
chr3_-_31069776 0.77 ENSDART00000167462
elongin B
chr10_+_44984946 0.77 ENSDART00000182520
H2A histone family, member Vb
chr13_+_46941930 0.77 ENSDART00000056962
F-box protein 5
chr24_+_37799818 0.77 ENSDART00000131975
TEL2, telomere maintenance 2, homolog (S. cerevisiae)
chr4_+_5334439 0.77 ENSDART00000180644
APEX nuclease (multifunctional DNA repair enzyme) 1
chr2_-_25140022 0.77 ENSDART00000134543
neutral cholesterol ester hydrolase 1a
chr15_-_31514818 0.77 ENSDART00000153978
high mobility group box 1b
chr8_-_16697912 0.77 ENSDART00000076542
retinal pigment epithelium-specific protein 65b
chr4_-_20108833 0.76 ENSDART00000100867
family with sequence similarity 3, member C
chr11_-_41220794 0.75 ENSDART00000192895
mitochondrial ribosomal protein S16
chr15_-_47822597 0.75 ENSDART00000193236
ENSDART00000161391

chr13_+_33298338 0.75 ENSDART00000131892
ENSDART00000143895
IQ motif containing C
chr21_-_20341836 0.75 ENSDART00000176689
retinol binding protein 4, like
chr19_-_27588842 0.74 ENSDART00000121643
si:dkeyp-46h3.2
chr19_+_3215466 0.74 ENSDART00000181288
zgc:86598
chr14_-_38827442 0.73 ENSDART00000160000
spindle apparatus coiled-coil protein 1
chr4_-_71110826 0.73 ENSDART00000167431
si:dkeyp-80d11.1
chr9_-_18911608 0.73 ENSDART00000138785
si:dkey-239h2.3
chr21_-_5077715 0.72 ENSDART00000081954
HAUS augmin-like complex, subunit 1
chr3_-_29977495 0.71 ENSDART00000077111
hydroxysteroid (17-beta) dehydrogenase 14
chr1_-_53277660 0.71 ENSDART00000014232
zinc finger protein 330
chr18_+_31117136 0.70 ENSDART00000138403
transcription factor 25 (basic helix-loop-helix)
chr7_+_22981909 0.69 ENSDART00000122449
cyclin B3
chr2_+_35595454 0.69 ENSDART00000098734
calcyclin binding protein
chr9_+_8396755 0.69 ENSDART00000043067
zgc:171776
chr4_+_69577362 0.68 ENSDART00000160913
zinc finger protein 1030
chr21_-_41065369 0.68 ENSDART00000143749
leucyl-tRNA synthetase b
chr14_-_4170654 0.68 ENSDART00000188347
si:dkey-185e18.7
chr2_+_10821579 0.68 ENSDART00000179694
glomulin, FKBP associated protein a
chr8_+_23356264 0.67 ENSDART00000145062
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a
chr23_+_36063599 0.67 ENSDART00000103147
homeobox C12a
chr11_+_6882049 0.66 ENSDART00000075998
kelch-like family member 26
chr20_+_31217495 0.65 ENSDART00000020252
protein disulfide isomerase family A, member 6
chr13_+_51579851 0.65 ENSDART00000163847
NK6 homeobox 2
chr1_+_35862550 0.65 ENSDART00000132118
si:ch211-194g2.4
chr5_+_25681174 0.65 ENSDART00000134773
zinc finger, AN1-type domain 5a
chr16_+_15114645 0.65 ENSDART00000158483
MDM2 binding protein
chr9_+_23003208 0.65 ENSDART00000021060
ELL associated factor 2
chr21_-_26495700 0.65 ENSDART00000109379
CD248 molecule, endosialin b
chr21_+_44684577 0.64 ENSDART00000099528
sprouty homolog 4 (Drosophila)
chr8_+_39619087 0.63 ENSDART00000134822
musashi RNA-binding protein 1
chr5_+_32141790 0.63 ENSDART00000041504
tescalcin b
chr24_+_11083146 0.63 ENSDART00000009473
zinc finger, AN1-type domain 1
chr17_+_24064014 0.62 ENSDART00000182782
ENSDART00000139063
ENSDART00000132755
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2b
chr20_+_18703454 0.62 ENSDART00000152342
eukaryotic translation initiation factor 5
chr20_+_25586099 0.61 ENSDART00000063122
ENSDART00000134047
cytochrome P450, family 2, subfamily P, polypeptide 10
chr2_-_21170517 0.60 ENSDART00000135417
bmi1 polycomb ring finger oncogene 1b
chr16_+_35401543 0.60 ENSDART00000171608
RAB42, member RAS oncogene family
chr19_+_1872794 0.60 ENSDART00000013217
small nuclear ribonucleoprotein D1 polypeptide
chr5_-_41645058 0.59 ENSDART00000051092
RIO kinase 2 (yeast)
chr11_+_37720756 0.59 ENSDART00000173337
small nuclear ribonucleoprotein polypeptide E
chr5_-_52215926 0.59 ENSDART00000163973
ENSDART00000193602
leucyl/cystinyl aminopeptidase
chr17_+_24851951 0.58 ENSDART00000180746
connexin 35.4
chr20_+_11734029 0.58 ENSDART00000179959
si:ch211-155o21.3
chr13_+_43247936 0.57 ENSDART00000126850
ENSDART00000165331
SPARC related modular calcium binding 2
chr5_+_26121393 0.57 ENSDART00000002221
beta-carotene 15, 15-dioxygenase 2, like
chr16_+_9762261 0.57 ENSDART00000020654
proteasome 26S subunit, non-ATPase 4b
chr2_-_56649883 0.57 ENSDART00000191786
glutathione peroxidase 4b
chr4_+_69375564 0.57 ENSDART00000150334
si:dkey-246j6.1
chr3_-_26204867 0.57 ENSDART00000103748
glycerophosphodiester phosphodiesterase domain containing 3a
chr23_+_36340520 0.57 ENSDART00000011201
coatomer protein complex, subunit zeta 1
chr6_+_36459897 0.57 ENSDART00000104248
ENSDART00000145753
leucine rich repeat containing 15
chr14_-_38828057 0.57 ENSDART00000186088
spindle apparatus coiled-coil protein 1
chr13_-_35459928 0.56 ENSDART00000144109
SLX4 interacting protein
chr14_+_36220479 0.56 ENSDART00000148319
paired-like homeodomain 2
chr21_-_2310064 0.56 ENSDART00000169520
si:ch211-241b2.1
chr2_-_30912922 0.56 ENSDART00000141669
myosin, light chain 12, genome duplicate 2
chr19_+_18903533 0.56 ENSDART00000157523
ENSDART00000166562
solute carrier family 39 (zinc transporter), member 7
chr17_-_42213285 0.55 ENSDART00000140549
NK2 homeobox 2a
chr15_+_834697 0.55 ENSDART00000154861
ENSDART00000160694
si:dkey-7i4.14
zgc:174573
chr14_-_24101897 0.55 ENSDART00000143695
cytoplasmic polyadenylation element binding protein 4a
chr19_+_13410903 0.54 ENSDART00000165033
ENSDART00000168672
serine/arginine-rich splicing factor 4
chr22_-_17489040 0.54 ENSDART00000141286
si:ch211-197g15.6
chr5_+_9134187 0.54 ENSDART00000132240
Pim proto-oncogene, serine/threonine kinase, related 123
chr17_+_43595692 0.54 ENSDART00000156271
cilia and flagella associated protein 99
chr8_+_21133307 0.54 ENSDART00000056405
mago homolog, exon junction complex core component
chr3_+_41922114 0.54 ENSDART00000138280
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr23_-_10175898 0.53 ENSDART00000146185
keratin 5
chr16_-_25699554 0.53 ENSDART00000155899
ENSDART00000114495
DEAD (Asp-Glu-Ala-Asp) box helicase 61
chr23_-_3758637 0.53 ENSDART00000131536
ENSDART00000139408
ENSDART00000137826
high mobility group AT-hook 1a
chr11_-_7147540 0.53 ENSDART00000143942
bone morphogenetic protein 7a
chr17_-_6599484 0.53 ENSDART00000156927
si:ch211-189e2.2
chr16_-_27566552 0.52 ENSDART00000142102
zgc:153215
chr5_+_25680845 0.52 ENSDART00000139701
ENSDART00000009952
zinc finger, AN1-type domain 5a
chr16_+_14201401 0.52 ENSDART00000113679
death associated protein 3
chr21_+_7131970 0.51 ENSDART00000161921
zgc:113019
chr6_-_7020162 0.51 ENSDART00000148982
bridging integrator 1b
chr17_-_49438873 0.51 ENSDART00000004424
zinc finger protein 292a
chr13_+_22675802 0.51 ENSDART00000145538
ENSDART00000143312
zgc:193505
chr17_-_51222510 0.51 ENSDART00000166687
presenilin 1
chr14_+_18782610 0.51 ENSDART00000164468
si:ch211-111e20.1
chr5_+_53482597 0.51 ENSDART00000180333

chr2_-_38080075 0.51 ENSDART00000056544
TOX high mobility group box family member 4 a
chr7_+_19835569 0.50 ENSDART00000149812
ovo-like zinc finger 1a
chr25_-_27541621 0.49 ENSDART00000130678
sperm adhesion molecule 1
chr21_-_25756119 0.49 ENSDART00000002341
claudin c
chr7_+_10562118 0.49 ENSDART00000185188
ENSDART00000168801
zinc finger, AN1-type domain 6
chr23_-_36446307 0.49 ENSDART00000136623
zgc:174906
chr12_-_30777540 0.49 ENSDART00000126466
ectonucleoside triphosphate diphosphohydrolase 1
chr19_+_26714949 0.49 ENSDART00000188540
zgc:100906
chr21_-_40348790 0.49 ENSDART00000178123

chr5_-_56948058 0.48 ENSDART00000083074
ENSDART00000191028
si:ch211-127d4.3
chr2_+_30513887 0.48 ENSDART00000137048
membrane-associated ring finger (C3HC4) 6
chr19_-_3876877 0.48 ENSDART00000163711
thyroid hormone receptor associated protein 3b
chr14_-_10387377 0.48 ENSDART00000145118
COMM domain containing 5
chr18_-_2668698 0.48 ENSDART00000157510
RELT, TNF receptor
chr16_+_35535375 0.47 ENSDART00000171675
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr16_+_19637384 0.47 ENSDART00000184773
ENSDART00000191895
ENSDART00000182020
ENSDART00000135359
metastasis associated in colon cancer 1
chr11_+_13528437 0.47 ENSDART00000011362
arrestin domain containing 2
chr1_-_52790724 0.47 ENSDART00000139577
ENSDART00000100937
protein associated with topoisomerase II homolog 1 (yeast)
chr17_+_24848976 0.47 ENSDART00000062917
connexin 35.4
chr21_+_22878991 0.47 ENSDART00000186399
PCF11 cleavage and polyadenylation factor subunit
chr25_+_15994100 0.47 ENSDART00000144723
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr2_-_30912307 0.46 ENSDART00000188653
myosin, light chain 12, genome duplicate 2
chr18_-_40773413 0.46 ENSDART00000133797
vasodilator stimulated phosphoprotein b
chr5_-_28625515 0.46 ENSDART00000190782
ENSDART00000179736
ENSDART00000131729
tenascin C
chr7_+_73819078 0.46 ENSDART00000169756
Histone H2B 1/2
chr15_-_18218227 0.46 ENSDART00000156332
bloodthirsty-related gene family, member 21
chr9_-_7683799 0.45 ENSDART00000102713
si:ch73-199e17.1
chr4_+_62184754 0.45 ENSDART00000168844
si:dkeyp-35e5.9
chr21_-_28920245 0.45 ENSDART00000132884
CXXC finger protein 5a
chr25_+_16880990 0.45 ENSDART00000020259
zgc:77158
chr21_+_19347655 0.45 ENSDART00000093155
heparanase
chr13_-_1151410 0.45 ENSDART00000007231
proteasome subunit beta 1
chr13_+_15933168 0.45 ENSDART00000131390
fidgetin-like 1
chr23_+_21492151 0.45 ENSDART00000025487
isoprenylcysteine carboxyl methyltransferase
chr9_+_34151367 0.44 ENSDART00000143991
G protein-coupled receptor 161
chr5_+_63329608 0.44 ENSDART00000139180
si:ch73-376l24.3
chr5_+_3892551 0.44 ENSDART00000134396
RPA interacting protein
chr20_+_34129465 0.44 ENSDART00000168804
ENSDART00000023211
phospholipase A2, group IVAb (cytosolic, calcium-dependent)
chr10_+_9550419 0.44 ENSDART00000064977
si:ch211-243g18.2
chr19_+_16015881 0.44 ENSDART00000187135
CTP synthase 1a
chr20_-_22476255 0.44 ENSDART00000103510
platelet-derived growth factor receptor, alpha polypeptide
chr10_+_35422802 0.43 ENSDART00000147303
HERV-H LTR-associating 2a, tandem duplicate 1
chr6_-_39313027 0.43 ENSDART00000012644
keratin 4
chr19_+_43017628 0.43 ENSDART00000182608
ENSDART00000015632
sodium/potassium transporting ATPase interacting 1
chr19_+_42432625 0.43 ENSDART00000076938
pogo transposable element derived with ZNF domain a
chr2_-_17115256 0.43 ENSDART00000190488
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr12_-_3077395 0.43 ENSDART00000002867
ENSDART00000126315
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr11_+_37612214 0.42 ENSDART00000172899
ENSDART00000077496
heterochromatin protein 1, binding protein 3
chr6_-_21091948 0.42 ENSDART00000057348
inhibin, alpha
chr9_-_9242777 0.42 ENSDART00000021191
U2 small nuclear RNA auxiliary factor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of sox10

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.6 GO:0035188 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.3 1.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.3 0.9 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.3 1.0 GO:0055130 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.2 1.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.2 2.2 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.2 1.9 GO:0034501 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.2 0.8 GO:1904667 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.2 0.8 GO:0016109 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.2 0.6 GO:1902176 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
0.2 0.8 GO:0000012 single strand break repair(GO:0000012)
0.2 0.5 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.1 0.5 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.1 0.8 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 1.0 GO:0021628 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.1 0.6 GO:0061072 iris morphogenesis(GO:0061072)
0.1 0.8 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.4 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 1.4 GO:0050482 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 0.3 GO:2000639 response to sterol(GO:0036314) cellular response to sterol(GO:0036315) SREBP-SCAP complex retention in endoplasmic reticulum(GO:0036316) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.6 GO:0033986 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.1 1.1 GO:0050714 positive regulation of protein secretion(GO:0050714)
0.1 0.5 GO:0055016 hypochord development(GO:0055016)
0.1 0.4 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.1 0.3 GO:0008344 adult locomotory behavior(GO:0008344)
0.1 1.4 GO:0021594 rhombomere formation(GO:0021594)
0.1 0.4 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 1.5 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 0.5 GO:0070285 pigment cell development(GO:0070285)
0.1 1.0 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.5 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.5 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.8 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.7 GO:0021703 locus ceruleus development(GO:0021703)
0.1 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.3 GO:0031627 telomeric loop formation(GO:0031627)
0.1 1.0 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.2 GO:0072196 proximal/distal pattern formation involved in nephron development(GO:0072047) proximal/distal pattern formation involved in pronephric nephron development(GO:0072196)
0.1 1.1 GO:0030073 insulin secretion(GO:0030073)
0.1 0.3 GO:0046102 adenosine catabolic process(GO:0006154) inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103)
0.1 0.4 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 0.4 GO:0098971 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.0 0.9 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0010456 cell proliferation in dorsal spinal cord(GO:0010456)
0.0 0.2 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.3 GO:0097638 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.0 1.0 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.1 GO:0060030 dorsal convergence(GO:0060030)
0.0 0.6 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 1.0 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.4 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.0 0.6 GO:0014812 muscle cell migration(GO:0014812)
0.0 0.2 GO:0010873 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.0 1.2 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.6 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.8 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.2 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.3 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.0 0.4 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.0 0.8 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.8 GO:0007004 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0 0.6 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.4 GO:2000406 positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
0.0 0.4 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 1.1 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 1.0 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 1.2 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.0 0.4 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.3 GO:0046471 cardiolipin metabolic process(GO:0032048) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.3 GO:0051122 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.6 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.3 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 1.5 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.1 GO:1902946 protein localization to early endosome(GO:1902946)
0.0 0.2 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 2.1 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 0.6 GO:0042476 odontogenesis(GO:0042476)
0.0 0.4 GO:0070828 heterochromatin organization(GO:0070828)
0.0 0.4 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.1 GO:0046324 regulation of glucose import(GO:0046324)
0.0 0.9 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.4 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 0.4 GO:0009712 catecholamine metabolic process(GO:0006584) catechol-containing compound metabolic process(GO:0009712)
0.0 0.7 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.4 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.2 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.0 0.5 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.6 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.5 GO:0043574 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 1.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.9 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.6 GO:0043171 peptide catabolic process(GO:0043171)
0.0 1.0 GO:0006354 DNA-templated transcription, elongation(GO:0006354)
0.0 0.2 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.5 GO:0001843 neural tube closure(GO:0001843) primary neural tube formation(GO:0014020)
0.0 0.2 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.8 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.0 0.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 1.4 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.0 0.4 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.4 GO:0008345 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.0 0.3 GO:0014823 response to activity(GO:0014823)
0.0 0.1 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.6 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 1.1 GO:0034504 protein localization to nucleus(GO:0034504)
0.0 0.1 GO:0042311 vasodilation(GO:0042311)
0.0 0.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.4 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.6 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.4 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.1 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.4 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.9 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 0.1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.2 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.6 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.6 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.9 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.3 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.3 GO:0051014 actin filament severing(GO:0051014)
0.0 0.6 GO:0015914 phospholipid transport(GO:0015914)
0.0 1.2 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.1 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) ventral spinal cord interneuron fate commitment(GO:0060579)
0.0 0.3 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.4 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 1.0 GO:0006413 translational initiation(GO:0006413)
0.0 0.8 GO:0001666 response to hypoxia(GO:0001666)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0034709 methylosome(GO:0034709)
0.2 0.8 GO:0070209 ASTRA complex(GO:0070209)
0.2 1.1 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.6 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.1 0.8 GO:0030891 VCB complex(GO:0030891)
0.1 0.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.4 GO:0097268 cytoophidium(GO:0097268)
0.1 0.5 GO:0043198 dendritic shaft(GO:0043198)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 1.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 1.0 GO:0045095 keratin filament(GO:0045095)
0.1 0.6 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 0.7 GO:0070652 HAUS complex(GO:0070652)
0.1 1.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 0.4 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.2 GO:0017177 glucosidase II complex(GO:0017177)
0.1 0.7 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 2.3 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 0.4 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 0.6 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.8 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.4 GO:0089701 U2AF(GO:0089701)
0.0 0.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.6 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.3 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.6 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.8 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.2 GO:0035517 PR-DUB complex(GO:0035517)
0.0 1.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.0 GO:0016605 PML body(GO:0016605)
0.0 0.6 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.2 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 1.9 GO:0016607 nuclear speck(GO:0016607)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.0 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.2 GO:0042627 chylomicron(GO:0042627)
0.0 1.0 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 1.2 GO:0005884 actin filament(GO:0005884)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.0 GO:0000776 kinetochore(GO:0000776)
0.0 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.9 GO:0000922 spindle pole(GO:0000922)
0.0 0.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.2 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.3 0.8 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.3 1.0 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.3 1.8 GO:0034632 retinol transporter activity(GO:0034632)
0.2 1.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 0.7 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.2 1.5 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.2 0.6 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 0.8 GO:0050251 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.2 0.7 GO:0044548 S100 protein binding(GO:0044548)
0.2 0.8 GO:0060182 apelin receptor activity(GO:0060182)
0.2 0.8 GO:0008311 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.1 0.6 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.1 0.9 GO:0015616 DNA translocase activity(GO:0015616)
0.1 1.3 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.6 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.4 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 0.6 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 0.3 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.1 0.4 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.4 GO:0048407 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.1 0.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.8 GO:0030619 U1 snRNA binding(GO:0030619)
0.1 0.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.3 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.1 0.3 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.5 GO:0048156 tau protein binding(GO:0048156)
0.1 0.4 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 1.2 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.4 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 1.7 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 1.0 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.2 GO:0072591 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
0.1 0.3 GO:0070573 metallodipeptidase activity(GO:0070573)
0.1 0.9 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.3 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.6 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 1.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.3 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 0.9 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.5 GO:0008506 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 0.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.5 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.7 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.8 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.7 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 1.2 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.3 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.0 0.4 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.4 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.0 0.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.4 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.8 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.3 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.2 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.5 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.4 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.6 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.6 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0043394 glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)
0.0 0.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.9 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0003994 aconitate hydratase activity(GO:0003994)
0.0 1.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 3.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 1.1 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 1.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.3 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.3 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.2 GO:0005165 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 0.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.3 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.9 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.4 GO:0003823 antigen binding(GO:0003823)
0.0 2.0 GO:0003735 structural constituent of ribosome(GO:0003735)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.6 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 2.2 PID E2F PATHWAY E2F transcription factor network
0.0 0.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.5 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 3.0 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 0.8 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 2.3 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 1.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 0.6 REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION Genes involved in Cleavage of Growing Transcript in the Termination Region
0.1 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 0.4 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 0.6 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 0.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 0.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 0.5 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.1 1.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.0 0.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.8 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.5 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.6 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.8 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import