Project

PRJEB1986: zebrafish developmental stages transcriptome

Navigation
Downloads

Results for snai2

Z-value: 0.79

Motif logo

Transcription factors associated with snai2

Gene Symbol Gene ID Gene Info
ENSDARG00000040046 snail family zinc finger 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
snai2dr11_v1_chr24_+_35387517_353875170.671.6e-03Click!

Activity profile of snai2 motif

Sorted Z-values of snai2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_59313465 1.56 ENSDART00000158067
ENSDART00000159419
thioredoxin domain containing 11
chr4_-_77216726 1.45 ENSDART00000099943
proteasome subunit beta 10
chr7_+_20917966 1.43 ENSDART00000129161
WD repeat containing, antisense to TP53
chr6_-_130849 1.40 ENSDART00000108710
si:zfos-323e3.4
chr9_-_48370645 1.36 ENSDART00000140185
collagen, type XXVIII, alpha 2a
chr19_-_35439237 1.35 ENSDART00000145883
anillin, actin binding protein
chr10_-_94184 1.30 ENSDART00000146125
tetratricopeptide repeat domain 3
chr21_-_21465111 1.18 ENSDART00000141487
nectin cell adhesion molecule 3b
chr9_+_15893093 1.11 ENSDART00000099483
ENSDART00000134657
si:dkey-14o1.20
chr5_+_22974019 1.10 ENSDART00000147157
ENSDART00000020434
bromodomain and WD repeat domain containing 3
chr13_+_2894536 1.08 ENSDART00000183678

chr11_-_45429199 1.05 ENSDART00000173111
replication factor C (activator 1) 4
chr8_+_39570615 1.05 ENSDART00000142557
leucine zipper, putative tumor suppressor 1
chr22_-_22231720 1.04 ENSDART00000160165
adaptor-related protein complex 3, delta 1 subunit
chr8_-_4892913 1.04 ENSDART00000126808
immunoglobulin superfamily, member 9b
chr20_+_30797329 1.03 ENSDART00000145066
NHS-like 1b
chr16_+_53203370 1.02 ENSDART00000154669
si:ch211-269k10.2
chr15_-_36365840 1.01 ENSDART00000192926
si:dkey-23k10.3
chr25_-_26736088 0.99 ENSDART00000067114
F-box and leucine-rich repeat protein 22
chr6_+_56141852 0.92 ENSDART00000149665
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr2_-_17694504 0.92 ENSDART00000133709
protein tyrosine phosphatase, receptor type, f, b
chr9_+_25775816 0.92 ENSDART00000127834
ENSDART00000189994
zinc finger E-box binding homeobox 2a
chr3_+_1179601 0.90 ENSDART00000173378
TRIO and F-actin binding protein b
chr22_+_2417105 0.88 ENSDART00000106415
zgc:113220
chr20_-_43723860 0.87 ENSDART00000122051
Mix paired-like homeobox
chr2_+_58877162 0.86 ENSDART00000122174

chr13_+_31133270 0.86 ENSDART00000014922
Rho GTPase activating protein 22
chr23_+_27778670 0.84 ENSDART00000053863
lysine (K)-specific methyltransferase 2D
chr4_+_4803698 0.83 ENSDART00000129252
solute carrier family 13 (sodium/sulfate symporter), member 4
chr8_+_15254564 0.80 ENSDART00000024433
solute carrier family 5 (sodium/sugar cotransporter), member 9
chr7_+_16166558 0.79 ENSDART00000173785
si:ch73-367j5.3
chr25_+_5249513 0.79 ENSDART00000126814

chr5_-_32505109 0.77 ENSDART00000188219
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr23_+_27779452 0.74 ENSDART00000134785
lysine (K)-specific methyltransferase 2D
chr17_+_27434626 0.74 ENSDART00000052446
vestigial-like family member 2b
chr20_+_50052627 0.74 ENSDART00000188799
cleavage and polyadenylation specific factor 2
chr7_+_74141297 0.73 ENSDART00000164992
RNA binding protein with multiple splicing
chr6_+_7555614 0.72 ENSDART00000187590
myosin, heavy chain 10, non-muscle
chr22_+_22438783 0.72 ENSDART00000147825
kinesin family member 14
chr17_-_51121525 0.72 ENSDART00000130412
ENSDART00000013418
aquarius intron-binding spliceosomal factor
chr17_-_49412313 0.72 ENSDART00000152100
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b
chr3_-_32362872 0.71 ENSDART00000035545
ENSDART00000012630
protein arginine methyltransferase 1
chr1_-_59407322 0.71 ENSDART00000161661
si:ch211-188p14.5
chr2_-_44282796 0.71 ENSDART00000163040
ENSDART00000166923
ENSDART00000056372
ENSDART00000109251
ENSDART00000132682
myelin protein zero
chr22_-_3595439 0.70 ENSDART00000083308
protein tyrosine phosphatase, receptor type, s, a
chr17_+_24843401 0.70 ENSDART00000110179
connexin 34.4
chr2_+_111919 0.69 ENSDART00000149391
FGGY carbohydrate kinase domain containing
chr24_+_19578935 0.69 ENSDART00000137175
sulfatase 1
chr4_+_57505842 0.68 ENSDART00000127643

chr5_-_54712159 0.68 ENSDART00000149207
cyclin B1
chr20_-_43743700 0.68 ENSDART00000100620
si:dkeyp-50f7.2
chr5_+_53482597 0.68 ENSDART00000180333

chr21_-_21515466 0.67 ENSDART00000147593
nectin cell adhesion molecule 3b
chr2_+_56012016 0.66 ENSDART00000146160
ENSDART00000188702
lysyl oxidase-like 5b
chr20_-_26491567 0.66 ENSDART00000147154
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr25_-_3623847 0.65 ENSDART00000172586
si:ch211-272n13.3
chr17_-_11151655 0.64 ENSDART00000156383

chr23_+_14771979 0.64 ENSDART00000137410
exosome component 10
chr14_+_989733 0.63 ENSDART00000161487
ENSDART00000127317
si:ch73-308l14.2
chr21_-_45882643 0.63 ENSDART00000168703
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr23_-_38054 0.63 ENSDART00000170393

chr21_-_45073764 0.63 ENSDART00000181390
ENSDART00000063714
Rap guanine nucleotide exchange factor (GEF) 6
chr11_-_11791718 0.63 ENSDART00000180476
cell division cycle 6 homolog (S. cerevisiae)
chr10_+_1052591 0.63 ENSDART00000123405
unc-5 netrin receptor C
chr4_-_38877924 0.62 ENSDART00000177741
zinc finger protein 1127
chr10_-_13116337 0.62 ENSDART00000164568
muscle, skeletal, receptor tyrosine kinase
chr22_+_9922301 0.61 ENSDART00000105924
bloody fingers
chr12_-_7710563 0.61 ENSDART00000187382

chr17_-_2596125 0.61 ENSDART00000175740
zona pellucida glycoprotein 3, tandem duplicate 2
chr13_+_23157053 0.61 ENSDART00000162359
sorbin and SH3 domain containing 1
chr17_+_1360192 0.59 ENSDART00000184561
SIVA1, apoptosis-inducing factor
chr18_+_5308392 0.59 ENSDART00000179072
deoxyuridine triphosphatase
chr2_-_23677422 0.58 ENSDART00000079131
chromodomain protein, Y-like
chr15_-_18574716 0.58 ENSDART00000142010
ENSDART00000019006
neural cell adhesion molecule 1b
chr3_-_32965848 0.58 ENSDART00000050930
caspase 6, apoptosis-related cysteine peptidase
chr13_+_34689663 0.57 ENSDART00000133661
taspase, threonine aspartase, 1
chr3_+_43086548 0.57 ENSDART00000163579
si:dkey-43p13.5
chr5_+_18014931 0.56 ENSDART00000142562
activating signal cointegrator 1 complex subunit 2
chr21_-_2958422 0.56 ENSDART00000174091
zgc:194215
chr24_-_31904924 0.56 ENSDART00000156060
ENSDART00000129741
ENSDART00000154276
si:ch73-78o10.1
chr4_-_43280244 0.55 ENSDART00000150762
si:dkeyp-53e4.1
chr11_-_8782871 0.55 ENSDART00000158546
si:ch211-51h4.2
chr20_-_23426339 0.54 ENSDART00000004625
zygote arrest 1
chr14_-_26482096 0.54 ENSDART00000187280
SMAD family member 5
chr23_-_27607039 0.54 ENSDART00000183639
PHD finger protein 8
chr3_+_14641962 0.54 ENSDART00000091070
zgc:158403
chr10_+_5954787 0.54 ENSDART00000161887
ENSDART00000160345
ENSDART00000190046
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr3_-_60027255 0.53 ENSDART00000189252
ENSDART00000154684
RecQ helicase-like 5
chr4_+_72235562 0.53 ENSDART00000168547
si:cabz01071912.2
chr8_+_19668654 0.53 ENSDART00000091436
forkhead box E3
chr21_-_43666420 0.53 ENSDART00000139008
ENSDART00000183996
ENSDART00000183395
si:dkey-229d11.3
si:dkey-229d11.5
chr24_-_9294134 0.53 ENSDART00000082434
TGFB-induced factor homeobox 1
chr12_+_30705769 0.53 ENSDART00000186448
ENSDART00000066259
potassium channel, subfamily K, member 1a
chr16_+_23961276 0.53 ENSDART00000192754
apolipoprotein Eb
chr3_-_30888415 0.53 ENSDART00000124458
lysine methyltransferase 5C
chr16_+_27444098 0.52 ENSDART00000157690
inversin
chr17_+_15041647 0.52 ENSDART00000108999
sterile alpha motif domain containing 4A
chr1_+_41609676 0.52 ENSDART00000183675
mannosyl-oligosaccharide glucosidase
chr25_-_12730260 0.51 ENSDART00000171834
kelch domain containing 4
chr3_-_15139293 0.51 ENSDART00000161213
ENSDART00000146053
family with sequence similarity 173, member A
chr12_+_48784731 0.51 ENSDART00000158348
zinc finger, MIZ-type containing 1b
chr23_-_44677315 0.51 ENSDART00000143054
kinesin family member 1C
chr22_+_30195257 0.50 ENSDART00000027803
ENSDART00000172496
adducin 3 (gamma) a
chr7_-_26571994 0.50 ENSDART00000128801
si:dkey-62k3.6
chr11_-_35575791 0.49 ENSDART00000031441
ENSDART00000188513
ENSDART00000183609
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb
chr23_+_28077953 0.49 ENSDART00000186122
ENSDART00000111570
solute carrier family 26, member 10
chr17_+_51906053 0.49 ENSDART00000159072
ENSDART00000056869
feline leukemia virus subgroup C cellular receptor family, member 2a
chr18_+_17786548 0.49 ENSDART00000189493
ENSDART00000146133
si:ch211-216l23.1
chr5_+_20693724 0.48 ENSDART00000141368
si:ch211-240b21.2
chr2_+_4208323 0.48 ENSDART00000167906
GATA binding protein 6
chr14_+_48862987 0.48 ENSDART00000167810
zgc:154054
chr6_-_10728057 0.46 ENSDART00000002247
Sp3b transcription factor
chr7_+_12835048 0.46 ENSDART00000016465
connexin 36.7
chr6_-_51556308 0.46 ENSDART00000149033
retinoblastoma-like 1 (p107)
chr10_-_57270 0.46 ENSDART00000058411
holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
chr8_+_999421 0.45 ENSDART00000149528
fatty acid binding protein 1b, tandem duplicate 1
chr1_-_55196103 0.45 ENSDART00000140153
methylthioribose-1-phosphate isomerase 1
chr21_-_217589 0.44 ENSDART00000185017

chr15_+_36096689 0.44 ENSDART00000049849
collagen, type IV, alpha 3
chr5_+_42259002 0.44 ENSDART00000083778
Era-like 12S mitochondrial rRNA chaperone 1
chr4_+_77993977 0.43 ENSDART00000174118
telomeric repeat binding factor a
chr18_+_6857071 0.43 ENSDART00000018735
ENSDART00000181969
DnaJ (Hsp40) homolog, subfamily A, member 2, like
chr3_+_41647637 0.43 ENSDART00000050332
guanine nucleotide binding protein (G protein) alpha 12a
chr3_+_49521106 0.43 ENSDART00000162799
crumbs homolog 3a
chr12_-_7234915 0.43 ENSDART00000048866
inositol polyphosphate multikinase b
chr6_+_1724889 0.43 ENSDART00000157415
activin A receptor type 2Ab
chr14_+_18785727 0.43 ENSDART00000184452
si:ch211-111e20.1
chr22_-_12304591 0.42 ENSDART00000136408
zinc finger, RAN-binding domain containing 3
chr11_+_7528599 0.42 ENSDART00000171813
adhesion G protein-coupled receptor L2a
chr16_-_31791165 0.42 ENSDART00000148389
chromodomain helicase DNA binding protein 4b
chr8_+_247163 0.42 ENSDART00000122378
centrosomal protein 120
chr10_+_19596214 0.42 ENSDART00000183110

chr2_-_7605121 0.42 ENSDART00000182099

chr13_-_31296358 0.41 ENSDART00000030946
PR domain containing 8
chr15_-_33834577 0.41 ENSDART00000163354
matrix metallopeptidase 13b
chr23_+_25201077 0.41 ENSDART00000136675
si:dkey-151g10.3
chr19_-_21716593 0.41 ENSDART00000155126
zinc finger protein 516
chr17_+_24590177 0.40 ENSDART00000092941
rearranged L-myc fusion
chr1_-_7673376 0.40 ENSDART00000013264
arginine and glutamate rich 1b
chr15_-_16177603 0.40 ENSDART00000156352
si:ch211-259g3.4
chr22_-_16758438 0.40 ENSDART00000132829
PATJ, crumbs cell polarity complex component
chr7_-_58867188 0.40 ENSDART00000187006

chr25_+_9027831 0.40 ENSDART00000155855
im:7145024
chr7_+_30988570 0.39 ENSDART00000180613
ENSDART00000185625
tight junction protein 1a
chr23_+_578218 0.39 ENSDART00000055134
opioid growth factor receptor
chr18_+_13077800 0.39 ENSDART00000161153
gigaxonin
chr5_-_68244564 0.39 ENSDART00000169350

chr6_-_10728921 0.38 ENSDART00000151484
Sp3b transcription factor
chr12_-_2869565 0.38 ENSDART00000152772
zinc finger, DHHC-type containing 16b
chr14_+_26546175 0.38 ENSDART00000105932
si:dkeyp-110e4.11
chr18_+_6641542 0.38 ENSDART00000160379
C2 calcium-dependent domain containing 5
chr22_+_1589407 0.37 ENSDART00000175704
si:ch211-255f4.11
chr1_+_34696503 0.37 ENSDART00000186106

chr7_+_14005111 0.37 ENSDART00000187365
furin (paired basic amino acid cleaving enzyme) a
chr3_+_40255408 0.37 ENSDART00000074746
Smith-Magenis syndrome chromosome region, candidate 8a
chr22_+_2686673 0.37 ENSDART00000161580
si:dkey-20i20.15
chr2_+_23677179 0.37 ENSDART00000153918
oxidative stress responsive 1a
chr16_+_41060161 0.37 ENSDART00000141130
SREBF chaperone
chr18_-_48492951 0.37 ENSDART00000146346
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 6
chr16_-_19568795 0.36 ENSDART00000185141
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr24_+_9372292 0.36 ENSDART00000082422
ENSDART00000191127
ENSDART00000180510
si:ch211-285f17.1
chr10_-_3416258 0.36 ENSDART00000005168
DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
chr10_-_108952 0.36 ENSDART00000127228
tetratricopeptide repeat domain 3
chr7_-_50367642 0.36 ENSDART00000134941
protein regulator of cytokinesis 1b
chr18_-_48508585 0.36 ENSDART00000133364
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 4
chr6_-_55399214 0.35 ENSDART00000168367
cathepsin A
chr1_-_24349759 0.35 ENSDART00000142740
ENSDART00000177989
LPS-responsive vesicle trafficking, beach and anchor containing
chr12_-_990149 0.35 ENSDART00000054367
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2b
chr9_-_28990649 0.35 ENSDART00000078823
protein tyrosine phosphatase, non-receptor type 4a
chr4_-_41269844 0.35 ENSDART00000186177

chr14_-_1998501 0.35 ENSDART00000189052
protocadherin 2 gamma 5
chr20_+_36730049 0.34 ENSDART00000045948
nuclear receptor coactivator 1
chr21_+_30794351 0.34 ENSDART00000139486
zgc:158225
chr4_+_38344 0.34 ENSDART00000170197
ENSDART00000175348
putative homeodomain transcription factor 2
chr5_-_36948586 0.33 ENSDART00000193606
H3 histone, family 3C
chr16_-_34258931 0.33 ENSDART00000145485
phosphatase and actin regulator 4b
chr21_+_30351256 0.33 ENSDART00000078341
forkhead box I3a
chr2_-_58075414 0.33 ENSDART00000161920
nectin cell adhesion molecule 4
chr19_+_791538 0.32 ENSDART00000146554
ENSDART00000138406
transmembrane protein 79a
chr22_-_26251563 0.32 ENSDART00000060888
ENSDART00000142821
coiled-coil domain containing 130
chr17_+_25332711 0.32 ENSDART00000082319
transmembrane protein 54a
chr20_+_42978499 0.32 ENSDART00000138793
si:ch211-203k16.3
chr12_+_30706158 0.32 ENSDART00000133869
potassium channel, subfamily K, member 1a
chr14_-_38865800 0.32 ENSDART00000173047
glutathione reductase
chr8_-_25697279 0.32 ENSDART00000143938
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ga
chr16_+_26747766 0.31 ENSDART00000183257
RAD54 homolog B (S. cerevisiae)
chr18_-_26781616 0.31 ENSDART00000136776
ENSDART00000076484
KTI12 chromatin associated homolog
chr6_+_58289335 0.31 ENSDART00000177399
Ral GTPase activating protein, beta subunit (non-catalytic)
chr22_-_8910567 0.31 ENSDART00000187896
ENSDART00000188511
ENSDART00000175764

chr23_+_2560005 0.31 ENSDART00000186906
gamma-glutamyltransferase 7
chr13_-_11800281 0.31 ENSDART00000079392
zmp:0000000662
chr1_+_56180416 0.31 ENSDART00000089358
crumbs homolog 3b
chr3_-_62403550 0.30 ENSDART00000055055
SRY (sex determining region Y)-box 8b
chr25_-_2081371 0.30 ENSDART00000104915
ENSDART00000156925
wingless-type MMTV integration site family, member 7Bb
chr25_-_255971 0.30 ENSDART00000162006

chr5_+_40224938 0.30 ENSDART00000142897
si:dkey-193c22.2
chr11_-_25853212 0.30 ENSDART00000145655
transmembrane protein 51b
chr2_-_43851915 0.29 ENSDART00000146493
zinc finger E-box binding homeobox 1a
chr14_+_16937997 0.29 ENSDART00000163013
ENSDART00000167856
LIM and calponin homology domains 1b
chr12_-_48312647 0.29 ENSDART00000114415
activating signal cointegrator 1 complex subunit 1

Network of associatons between targets according to the STRING database.

First level regulatory network of snai2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0008356 asymmetric cell division(GO:0008356)
0.3 1.4 GO:0030575 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.3 0.8 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.2 0.6 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.2 0.5 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.2 0.5 GO:1902746 negative regulation of epithelial cell differentiation(GO:0030857) regulation of lens fiber cell differentiation(GO:1902746)
0.2 0.7 GO:0034969 histone arginine methylation(GO:0034969)
0.2 1.6 GO:0003428 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.2 0.5 GO:0071830 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.2 0.5 GO:0034770 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.2 0.5 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.1 0.6 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 1.0 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.1 0.9 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.1 0.5 GO:0072116 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.1 1.0 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 0.5 GO:0097037 heme export(GO:0097037)
0.1 0.4 GO:0046689 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.1 0.7 GO:0070650 actin filament bundle distribution(GO:0070650)
0.1 1.6 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.1 0.9 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.4 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.7 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) histone mRNA metabolic process(GO:0008334)
0.1 0.4 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.1 1.0 GO:0086003 cardiac muscle cell contraction(GO:0086003)
0.1 0.5 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.1 0.5 GO:0043011 myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011)
0.1 1.4 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 0.7 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.1 0.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.6 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.1 0.4 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.1 0.7 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 0.9 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.1 0.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.5 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.2 GO:0003403 optic vesicle formation(GO:0003403)
0.1 0.6 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 1.9 GO:0007286 spermatid development(GO:0007286)
0.1 0.4 GO:0048478 replication fork protection(GO:0048478)
0.1 0.6 GO:0000022 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.1 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.9 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 1.0 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.1 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.1 GO:1904088 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.0 0.3 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.7 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.2 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.4 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.0 0.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.4 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.5 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.0 0.9 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 1.0 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.1 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.0 0.2 GO:0061055 myotome development(GO:0061055)
0.0 0.4 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.2 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.0 0.4 GO:1901381 positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.3 GO:0007045 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.0 0.4 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.4 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.3 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.5 GO:2000134 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.0 0.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 0.5 GO:0008272 sulfate transport(GO:0008272)
0.0 0.1 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.1 GO:1901888 regulation of cell junction assembly(GO:1901888)
0.0 0.9 GO:0001706 endoderm formation(GO:0001706)
0.0 0.3 GO:1902287 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.1 GO:0015864 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.0 0.5 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0043217 myelin maintenance(GO:0043217)
0.0 0.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.5 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.8 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.1 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.0 0.4 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.3 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 0.3 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.5 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.3 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 1.0 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.1 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561) apoptotic process involved in development(GO:1902742)
0.0 1.1 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 0.4 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 0.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.0 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 1.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 1.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.5 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 1.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 1.4 GO:0015030 Cajal body(GO:0015030)
0.1 0.3 GO:0016460 myosin II complex(GO:0016460)
0.1 0.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.6 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.4 GO:0031526 brush border membrane(GO:0031526)
0.0 0.7 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.2 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 1.0 GO:0043195 terminal bouton(GO:0043195)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0032797 SMN complex(GO:0032797)
0.0 0.7 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0005592 collagen type XI trimer(GO:0005592)
0.0 0.2 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.9 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.4 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.4 GO:0070187 telosome(GO:0070187)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.4 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.3 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.7 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 1.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.1 GO:0043296 apical junction complex(GO:0043296)
0.0 1.2 GO:0005871 kinesin complex(GO:0005871)
0.0 1.3 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.4 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.2 1.4 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.2 0.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 0.5 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.2 0.8 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.4 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.4 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 0.5 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 2.0 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 1.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 1.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.3 GO:0032034 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
0.1 0.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.8 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 0.6 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.1 0.3 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.1 0.6 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.5 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.5 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.8 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.4 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 0.3 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.4 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.5 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.7 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.7 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.5 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.5 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.1 GO:0072545 tyrosine binding(GO:0072545)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.5 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.4 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.4 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.5 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.5 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.5 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.6 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 2.1 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.1 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0038131 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.6 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 0.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 2.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.2 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.3 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.5 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.7 PID ATR PATHWAY ATR signaling pathway
0.0 0.6 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.6 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.0 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 1.0 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 0.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 0.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 2.2 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.0 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.7 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.6 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.5 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions