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PRJEB1986: zebrafish developmental stages transcriptome

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Results for smarcc1a+smarcc1b

Z-value: 1.01

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Transcription factors associated with smarcc1a+smarcc1b

Gene Symbol Gene ID Gene Info
ENSDARG00000017397 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1a
ENSDARG00000098919 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
smarcc1bdr11_v1_chr19_-_19379084_19379084-0.272.6e-01Click!
smarcc1adr11_v1_chr16_-_42461263_42461263-0.223.6e-01Click!

Activity profile of smarcc1a+smarcc1b motif

Sorted Z-values of smarcc1a+smarcc1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_47115787 5.67 ENSDART00000192601

chr3_-_4303262 4.16 ENSDART00000112819
si:dkey-73p2.2
chr7_+_35068036 3.71 ENSDART00000022139
zgc:136461
chr1_-_59252973 3.67 ENSDART00000167061
si:ch1073-286c18.5
chr16_+_18974064 3.48 ENSDART00000079248
solute carrier family 6 (neutral amino acid transporter), member 19b
chr24_-_40009446 3.16 ENSDART00000087422
amine oxidase, copper containing 1
chr11_+_24002503 2.62 ENSDART00000164702
chitinase, acidic.2
chr19_-_21832441 2.58 ENSDART00000151272
ENSDART00000151442
ENSDART00000150168
ENSDART00000148797
ENSDART00000128196
ENSDART00000149259
ENSDART00000052556
ENSDART00000149658
ENSDART00000149639
ENSDART00000148424
myelin basic protein a
chr2_-_293793 2.54 ENSDART00000082091
si:ch73-40a17.3
chr12_-_30841679 2.51 ENSDART00000105594
crystallin, gamma MX
chr6_-_13783604 2.37 ENSDART00000149536
ENSDART00000041269
ENSDART00000150102
crystallin, beta A2a
chr16_+_14033121 2.36 ENSDART00000135844
RUN and SH3 domain containing 1
chr8_+_43053519 2.35 ENSDART00000147178
prion protein a
chr6_-_12588044 2.30 ENSDART00000047896
solute carrier family 15 (oligopeptide transporter), member 1b
chr5_-_20678300 2.11 ENSDART00000088639
WSC domain containing 2
chr5_-_50992690 2.09 ENSDART00000149553
ENSDART00000097460
ENSDART00000192021
3-hydroxy-3-methylglutaryl-CoA reductase a
chr18_-_5692292 2.09 ENSDART00000121503
complexin 3b
chr15_+_28989573 1.94 ENSDART00000076648
CAP-GLY domain containing linker protein 3
chr9_+_56422311 1.89 ENSDART00000171958
G protein-coupled receptor 39
chr2_-_3437862 1.77 ENSDART00000053012
cytochrome P450, family 8, subfamily B, polypeptide 1
chr11_-_43104475 1.76 ENSDART00000125368
acylphosphatase 2, muscle type
chr24_+_35947077 1.75 ENSDART00000173406
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF b
chr9_-_12493628 1.71 ENSDART00000180832
insulin-like growth factor 2 mRNA binding protein 2a
chr5_-_22501663 1.68 ENSDART00000133174
si:dkey-27p18.5
chr22_-_10110959 1.67 ENSDART00000031005
ENSDART00000147580
glutaminase 2b (liver, mitochondrial)
chr2_-_155270 1.67 ENSDART00000131177
adenylate cyclase 1b
chr3_-_61185746 1.65 ENSDART00000028219
parvalbumin 4
chr19_-_703898 1.65 ENSDART00000181096
ENSDART00000121462
solute carrier family 6 (neutral amino acid transporter), member 19a, tandem duplicate 2
chr4_+_74131530 1.65 ENSDART00000174125

chr23_-_40250886 1.61 ENSDART00000041912
transglutaminase 1 like 3
chr16_+_49005321 1.59 ENSDART00000160919

chr22_+_1049367 1.58 ENSDART00000065380
calcium/calmodulin-dependent protein kinase IGa
chr1_+_9071324 1.58 ENSDART00000184194

chr1_+_45323142 1.58 ENSDART00000132210
epithelial membrane protein 1
chr16_-_36834505 1.54 ENSDART00000141275
ENSDART00000139588
ENSDART00000041993
purine nucleoside phosphorylase 4b
chr21_+_6328801 1.53 ENSDART00000163577
formin binding protein 1b
chr1_-_54765262 1.53 ENSDART00000150362
si:ch211-197k17.3
chr2_+_46589798 1.49 ENSDART00000128457
ENSDART00000145347
EPH receptor B1
chr17_+_22311413 1.49 ENSDART00000151929
solute carrier family 8 (sodium/calcium exchanger), member 1b
chr12_+_22607761 1.49 ENSDART00000153112
si:dkey-219e21.2
chr5_+_21931124 1.49 ENSDART00000137627
si:ch73-92i20.1
chr15_-_45674213 1.46 ENSDART00000080072

chr7_+_34492744 1.46 ENSDART00000109635
ENSDART00000173844
calmodulin-like 4a
chr23_-_270847 1.45 ENSDART00000191867
ankyrin repeat and sterile alpha motif domain containing 1Aa
chr1_+_9004719 1.44 ENSDART00000006211
ENSDART00000137211
protein kinase C, beta a
chr21_-_42100471 1.44 ENSDART00000166148
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr11_-_10770053 1.44 ENSDART00000179213
solute carrier family 4, sodium bicarbonate transporter, member 10a
chr22_-_29191152 1.42 ENSDART00000132702
parvalbumin 7
chr3_+_3810919 1.42 ENSDART00000056035

chr22_+_19247255 1.36 ENSDART00000144053
si:dkey-21e2.10
chr5_+_62356304 1.35 ENSDART00000148381
aspartoacylase
chr16_-_13818061 1.33 ENSDART00000132982
ENSDART00000144856
leukocyte receptor cluster (LRC) member 9
chr13_-_293250 1.33 ENSDART00000138581
chitin synthase 1
chr13_+_23988442 1.31 ENSDART00000010918
angiotensinogen
chr3_+_4346854 1.30 ENSDART00000004273
si:dkey-73p2.3
chr5_-_37935607 1.29 ENSDART00000141233
ENSDART00000084868
ENSDART00000125857
sodium channel, voltage-gated, type IV, beta b
chr23_-_7799184 1.29 ENSDART00000190946
ENSDART00000165427
myelin transcription factor 1b
chr22_-_24297510 1.28 ENSDART00000163297
si:ch211-117l17.6
chr22_-_6562618 1.27 ENSDART00000106100
zgc:171490
chr9_+_33154841 1.27 ENSDART00000132465
dopey family member 2
chr12_+_47280839 1.25 ENSDART00000187574
ryanodine receptor 2
chr21_+_13353263 1.24 ENSDART00000114677
si:ch73-62l21.1
chr4_-_789645 1.21 ENSDART00000164441
microtubule-associated protein, RP/EB family, member 3b
chr10_-_105100 1.21 ENSDART00000145716
tetratricopeptide repeat domain 3
chr24_-_11309477 1.20 ENSDART00000137257
myosin VIIA and Rab interacting protein
chr13_+_1430094 1.18 ENSDART00000169888
si:ch211-165e15.1
chr19_+_1510971 1.18 ENSDART00000157721
solute carrier family 45 member 4
chr22_+_28337204 1.15 ENSDART00000163352
interphotoreceptor matrix proteoglycan 2b
chr1_-_45920632 1.15 ENSDART00000140890
patatin-like phospholipase domain containing 6
chr9_-_34915351 1.14 ENSDART00000100728
ENSDART00000139608
UPF3A, regulator of nonsense mediated mRNA decay
chr18_+_15841449 1.14 ENSDART00000141800
ENSDART00000091349
early endosome antigen 1
chr4_-_53047883 1.14 ENSDART00000157496
si:dkey-201g16.5
chr1_+_6640437 1.13 ENSDART00000147638
si:ch211-93g23.2
chr18_-_8312848 1.13 ENSDART00000092033
mitogen-activated protein kinase 8 interacting protein 2
chr17_-_3986236 1.12 ENSDART00000188794
ENSDART00000160830
si:ch1073-140o9.2
chr2_+_50862527 1.10 ENSDART00000169800
ENSDART00000158847
ENSDART00000160900
adenylate cyclase activating polypeptide 1a (pituitary) receptor type I
chr1_-_40227166 1.09 ENSDART00000146680
si:ch211-113e8.3
chr20_+_41664350 1.09 ENSDART00000186247
family with sequence similarity 184, member A
chr11_-_36963988 1.09 ENSDART00000168288
calcium channel, voltage-dependent, L type, alpha 1D subunit, a
chr7_-_5487593 1.09 ENSDART00000136594
Rho guanine nucleotide exchange factor (GEF) 11
chr5_+_61556172 1.08 ENSDART00000131937
ORAI calcium release-activated calcium modulator 2
chr13_-_7031033 1.07 ENSDART00000193211

chr5_-_69482891 1.07 ENSDART00000109487

chr2_+_20430366 1.06 ENSDART00000155108
si:ch211-153l6.6
chr21_+_26612777 1.06 ENSDART00000142667
estrogen-related receptor alpha
chr19_-_36675023 1.06 ENSDART00000132471
CUB and Sushi multiple domains 2
chr1_+_49266886 1.06 ENSDART00000137179
calcyon neuron-specific vesicular protein
chr9_+_13682133 1.05 ENSDART00000175639
membrane protein, palmitoylated 4a (MAGUK p55 subfamily member 4)
chr21_-_22485847 1.05 ENSDART00000162860
myosin VB
chr15_+_15314189 1.05 ENSDART00000156830
calcium/calmodulin-dependent protein kinase kinase 1, alpha b
chr10_-_20481763 1.05 ENSDART00000091156
ENSDART00000192358
transforming, acidic coiled-coil containing protein 1
chr10_+_1638876 1.04 ENSDART00000184484
ENSDART00000060946
ENSDART00000181251
small G protein signaling modulator 1b
chr3_+_56905103 1.04 ENSDART00000124728
ENSDART00000154408
otopetrin 2
chr3_+_24986145 1.04 ENSDART00000055428
chromobox homolog 7a
chr17_-_45247151 1.02 ENSDART00000186230
tau tubulin kinase 2a
chr18_-_12957451 1.02 ENSDART00000140403
SLIT-ROBO Rho GTPase activating protein 1a
chr19_+_4139065 1.02 ENSDART00000172524
si:dkey-218f9.10
chr24_-_33366188 1.01 ENSDART00000074161
solute carrier family 4 (anion exchanger), member 2b
chr1_+_45323400 1.01 ENSDART00000148906
ENSDART00000132366
epithelial membrane protein 1
chr2_+_47582488 1.00 ENSDART00000149967
secretogranin II (chromogranin C), b
chr7_+_25033924 1.00 ENSDART00000170873
sb:cb1058
chr13_+_13770980 0.99 ENSDART00000113089
solute carrier family 4, sodium borate transporter, member 11
chr20_-_40750953 0.99 ENSDART00000061256
connexin 28.9
chr12_+_46967789 0.97 ENSDART00000114866
ornithine aminotransferase
chr19_-_36234185 0.97 ENSDART00000186003
CUB and Sushi multiple domains 2
chr13_-_16222388 0.97 ENSDART00000182861
zgc:110045
chr14_+_49395437 0.97 ENSDART00000172850
TNFAIP3 interacting protein 1
chr20_-_39273505 0.96 ENSDART00000153114
clusterin
chr17_+_41302660 0.96 ENSDART00000059480
fos-like antigen 2
chr3_+_39922602 0.96 ENSDART00000193937
calcium channel, voltage-dependent, T type, alpha 1H subunit a
chr5_+_4338874 0.95 ENSDART00000141866
spermidine/spermine N1-acetyltransferase 1a, duplicate 1
chr3_+_7617353 0.95 ENSDART00000165551
zgc:109949
chr8_+_24861264 0.95 ENSDART00000099607
solute carrier family 6 (neutral amino acid transporter), member 17
chr4_+_60492313 0.93 ENSDART00000191043
ENSDART00000191631
si:dkey-211i20.2
chr5_+_20147830 0.93 ENSDART00000098727
SV2 related protein a
chr25_+_13498188 0.93 ENSDART00000015710
SNF related kinase b
chr20_-_34090740 0.93 ENSDART00000062539
ENSDART00000008140
phosducin b
chr7_+_17992455 0.93 ENSDART00000089211
ENSDART00000190881
EH domain binding protein 1-like 1a
chr18_-_20869175 0.93 ENSDART00000090079
synemin, intermediate filament protein
chr8_+_50983551 0.93 ENSDART00000142061
si:dkey-32e23.4
chr8_+_24854600 0.92 ENSDART00000156570
solute carrier family 6 (neutral amino acid transporter), member 17
chr6_+_59642695 0.91 ENSDART00000166373
ENSDART00000161030
R3H domain containing 2
chr23_-_12014931 0.91 ENSDART00000134652
si:dkey-178k16.1
chr20_-_27864964 0.91 ENSDART00000153311
synapse differentiation inducing 1-like
chr1_-_34750169 0.90 ENSDART00000149380
si:dkey-151m22.8
chr8_+_17933475 0.90 ENSDART00000100651
glutamate-rich 3
chr12_-_43982343 0.90 ENSDART00000161539

chr3_+_4266289 0.90 ENSDART00000101636
si:dkey-73p2.1
chr2_-_23778180 0.89 ENSDART00000136782
si:dkey-24c2.7
chr22_+_19188809 0.89 ENSDART00000134791
ENSDART00000133682
si:dkey-21e2.8
chr24_+_24923166 0.88 ENSDART00000065288
phosphate cytidylyltransferase 1, choline, beta a
chr4_-_5291256 0.88 ENSDART00000150864
si:ch211-214j24.9
chr6_+_11250316 0.87 ENSDART00000137122
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr7_-_9674073 0.87 ENSDART00000187902
leucine-rich repeat kinase 1
chr16_-_13613475 0.87 ENSDART00000139102
D site albumin promoter binding protein b
chr19_+_551963 0.87 ENSDART00000110495
A kinase (PRKA) anchor protein 9
chr19_+_43314700 0.87 ENSDART00000049045
ENSDART00000133158
matrilin 1
chr19_+_5072918 0.86 ENSDART00000037126
enolase 2
chr5_+_20035284 0.86 ENSDART00000191808
small G protein signaling modulator 1a
chr1_-_31505144 0.86 ENSDART00000087115
regulating synaptic membrane exocytosis 1b
chr25_-_22191733 0.85 ENSDART00000067478
plakophilin 3a
chr19_-_103289 0.85 ENSDART00000143118
adhesion G protein-coupled receptor B1b
chr13_-_40141630 0.85 ENSDART00000181618
ENSDART00000171583
ENSDART00000192780
cartilage acidic protein 1b
chr16_+_48714048 0.84 ENSDART00000148709
ENSDART00000150121
bromodomain containing 2b
chr9_-_21936841 0.84 ENSDART00000144843
LIM domain 7a
chr18_+_9635178 0.84 ENSDART00000183486
piccolo presynaptic cytomatrix protein b
chr5_+_19337108 0.84 ENSDART00000089078
acetyl-CoA carboxylase beta
chr1_+_51312752 0.84 ENSDART00000063938
microtubule associated serine/threonine kinase 1a
chr25_-_21085661 0.83 ENSDART00000099355
proline rich 5a (renal)
chr4_+_77735212 0.83 ENSDART00000160716
si:dkey-238k10.1
chr9_+_38481780 0.83 ENSDART00000087241
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr25_+_22643954 0.83 ENSDART00000182843
ENSDART00000121791
Usher syndrome 1C
chr22_+_8979955 0.83 ENSDART00000144005
si:ch211-213a13.1
chr19_+_49721 0.82 ENSDART00000160489
collagen, type XIV, alpha 1b
chr17_+_8183393 0.82 ENSDART00000155957
tubby like protein 4b
chr12_-_10315039 0.82 ENSDART00000152680
peptide YYb
chr6_+_27275716 0.81 ENSDART00000156434
ENSDART00000114347
selenocysteine lyase
chr8_-_11170114 0.81 ENSDART00000133532
si:ch211-204d2.4
chr14_-_1535430 0.81 ENSDART00000179228

chr2_+_30379650 0.80 ENSDART00000129542
cysteine-rich secretory protein LCCL domain containing 1b
chr9_-_22057658 0.80 ENSDART00000101944
crystallin, gamma MX, like 1
chr20_-_16548912 0.80 ENSDART00000137601
checkpoint suppressor 1
chr13_-_37545487 0.80 ENSDART00000131269
synaptotagmin XVI
chr5_-_67629263 0.80 ENSDART00000133753
zinc finger and BTB domain containing 20
chr12_+_4573696 0.80 ENSDART00000152534
si:dkey-94f20.4
chr20_+_7084154 0.79 ENSDART00000136448
finTRIM family, member 85
chr16_+_13818500 0.79 ENSDART00000135245
folliculin
chr12_-_4388704 0.79 ENSDART00000152168
si:ch211-173d10.1
chr2_+_47582681 0.79 ENSDART00000187579
secretogranin II (chromogranin C), b
chr6_-_35446110 0.79 ENSDART00000058773
regulator of G protein signaling 16
chr4_-_69189894 0.78 ENSDART00000169596
si:ch211-209j12.1
chr7_+_14005111 0.78 ENSDART00000187365
furin (paired basic amino acid cleaving enzyme) a
chr9_-_22076368 0.78 ENSDART00000128486
crystallin, gamma M2a
chr18_+_5137241 0.77 ENSDART00000159601
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr15_-_43978141 0.77 ENSDART00000041249
cysteine and histidine-rich domain (CHORD) containing 1a
chr9_-_12034444 0.77 ENSDART00000038651
zinc finger protein 804A
chr23_-_7797207 0.76 ENSDART00000181611
myelin transcription factor 1b
chr4_+_76671012 0.76 ENSDART00000005585
membrane-spanning 4-domains, subfamily A, member 17a.2
chr23_-_18024543 0.76 ENSDART00000139695
peptidase M20 domain containing 1, tandem duplicate 1
chr8_+_44714336 0.76 ENSDART00000145801
ELMO/CED-12 domain containing 3
chr20_+_34915945 0.76 ENSDART00000153064
synaptosomal-associated protein, 25a
chr8_+_14792830 0.76 ENSDART00000139972
calcium channel, voltage-dependent, R type, alpha 1E subunit a
chr5_+_15350954 0.75 ENSDART00000140990
ENSDART00000137287
ENSDART00000061653
phosphatidylethanolamine binding protein 1
chr17_-_29192987 0.75 ENSDART00000164302
spectrin, beta, non-erythrocytic 5
chr3_+_49097775 0.74 ENSDART00000169185
zgc:123284
chr13_-_10945288 0.74 ENSDART00000114315
ENSDART00000164667
ENSDART00000159482
ATP-binding cassette, sub-family G (WHITE), member 8
chr2_-_56387041 0.74 ENSDART00000036240
ceramide synthase 4b
chr5_-_35159379 0.74 ENSDART00000144105
FCH domain only 2
chr17_-_12389259 0.74 ENSDART00000185724
synaptosomal-associated protein, 25b
chr17_-_45247332 0.73 ENSDART00000016815
tau tubulin kinase 2a
chr4_+_76752707 0.73 ENSDART00000082121
membrane-spanning 4-domains, subfamily A, member 17A.4
chr3_+_45401472 0.72 ENSDART00000156693
BAI1-associated protein 3
chr24_+_39135419 0.72 ENSDART00000180941
TBC1 domain family, member 24
chr9_-_30363770 0.72 ENSDART00000147030
synaptotagmin-like 5
chr2_+_31600661 0.71 ENSDART00000139039
si:ch211-106h4.4
chr19_-_5805923 0.71 ENSDART00000134340
si:ch211-264f5.8
chr19_-_22621991 0.71 ENSDART00000175106
plectin a
chr24_+_26039464 0.71 ENSDART00000131017
tyrosine kinase, non-receptor, 2a
chr8_-_38403018 0.71 ENSDART00000134100
sorbin and SH3 domain containing 3
chr2_+_3452590 0.71 ENSDART00000153935
cytochrome P450, family 8, subfamily B, polypeptide 2

Network of associatons between targets according to the STRING database.

First level regulatory network of smarcc1a+smarcc1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.2 GO:0046677 response to antibiotic(GO:0046677)
0.6 1.9 GO:0015824 proline transport(GO:0015824)
0.5 2.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.5 1.4 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.4 1.6 GO:0048913 anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
0.3 1.4 GO:0070208 protein heterotrimerization(GO:0070208)
0.3 1.3 GO:1901073 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.3 1.1 GO:0003245 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.3 2.3 GO:0006857 oligopeptide transport(GO:0006857)
0.2 2.6 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.2 1.0 GO:0009447 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.2 0.6 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.2 0.8 GO:0090386 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.2 0.8 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.2 1.7 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.2 0.6 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.2 0.8 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.2 0.9 GO:1903146 regulation of mitophagy(GO:1903146)
0.2 2.4 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.2 0.5 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.2 0.6 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.2 0.5 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.1 0.4 GO:0019417 sulfur oxidation(GO:0019417)
0.1 0.4 GO:0035902 response to immobilization stress(GO:0035902)
0.1 1.2 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.1 0.7 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.2 GO:0034650 cortisol metabolic process(GO:0034650)
0.1 0.8 GO:0003321 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.1 1.6 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 1.0 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 0.9 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 2.4 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.4 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 0.5 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 1.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.5 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1 0.4 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.1 1.5 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 0.9 GO:0044805 late nucleophagy(GO:0044805)
0.1 0.3 GO:0022009 central nervous system vasculogenesis(GO:0022009)
0.1 0.9 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 0.6 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.8 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.1 0.3 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 1.5 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 0.6 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 0.4 GO:1901907 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.5 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1 0.8 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.4 GO:0033119 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 1.3 GO:0001990 regulation of systemic arterial blood pressure by hormone(GO:0001990)
0.1 0.3 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 1.0 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.1 1.1 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1 0.5 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 0.2 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.1 0.1 GO:0060347 trabecula formation(GO:0060343) heart trabecula formation(GO:0060347)
0.1 0.1 GO:2000378 negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.1 2.5 GO:0060536 cartilage morphogenesis(GO:0060536)
0.1 1.0 GO:0010002 cardioblast differentiation(GO:0010002)
0.1 1.1 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 0.4 GO:0071800 podosome assembly(GO:0071800)
0.1 0.4 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.1 0.3 GO:0072314 visceral serous pericardium development(GO:0061032) glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.1 0.4 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 0.7 GO:0030325 adrenal gland development(GO:0030325)
0.1 1.3 GO:0002574 thrombocyte differentiation(GO:0002574)
0.1 1.1 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 0.4 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.1 0.4 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.2 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.1 1.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 0.3 GO:0070254 mucus secretion(GO:0070254)
0.1 0.5 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.2 GO:0016038 absorption of visible light(GO:0016038)
0.1 2.1 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.1 0.9 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.1 0.7 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 1.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 6.5 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.8 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.4 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.5 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.4 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 2.4 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.4 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 1.7 GO:0061035 regulation of cartilage development(GO:0061035)
0.0 0.2 GO:0070459 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.0 0.3 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.3 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.5 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.7 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.2 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.2 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.8 GO:0002093 auditory receptor cell morphogenesis(GO:0002093)
0.0 0.3 GO:1904861 excitatory synapse assembly(GO:1904861)
0.0 0.4 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.7 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.2 GO:0015846 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 1.1 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.9 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.6 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 3.0 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 5.0 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 7.3 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 1.0 GO:0006817 phosphate ion transport(GO:0006817)
0.0 1.4 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.1 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 1.9 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.1 GO:0001779 natural killer cell differentiation(GO:0001779)
0.0 0.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.2 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.6 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.2 GO:1900028 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.0 0.2 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.5 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.4 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959)
0.0 0.7 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.6 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.3 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:0090134 coronary vasculature development(GO:0060976) mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.0 0.3 GO:0009251 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 1.6 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.2 GO:0071684 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 1.2 GO:0046328 regulation of JNK cascade(GO:0046328)
0.0 0.5 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.2 GO:0031179 peptide modification(GO:0031179)
0.0 0.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 2.3 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 2.6 GO:0007601 visual perception(GO:0007601)
0.0 0.8 GO:0051298 centrosome duplication(GO:0051298)
0.0 0.5 GO:0050868 negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 0.1 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 1.6 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.3 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 0.8 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.9 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.5 GO:0097553 release of sequestered calcium ion into cytosol(GO:0051209) calcium ion transmembrane import into cytosol(GO:0097553) calcium ion import into cytosol(GO:1902656)
0.0 0.3 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 1.0 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.5 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.3 GO:1901071 glucosamine-containing compound metabolic process(GO:1901071)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:0043247 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.3 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:0009749 response to glucose(GO:0009749)
0.0 0.2 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 0.4 GO:0050708 regulation of protein secretion(GO:0050708)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0006868 glutamine transport(GO:0006868)
0.0 0.4 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.8 GO:0051028 mRNA transport(GO:0051028)
0.0 0.1 GO:0099565 excitatory postsynaptic potential(GO:0060079) chemical synaptic transmission, postsynaptic(GO:0099565)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.2 1.5 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.2 0.5 GO:0033268 node of Ranvier(GO:0033268)
0.2 1.3 GO:0030428 cell septum(GO:0030428)
0.1 1.5 GO:0042583 chromaffin granule(GO:0042583)
0.1 2.6 GO:0043209 myelin sheath(GO:0043209)
0.1 0.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.4 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.1 2.8 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.9 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 2.5 GO:0043195 terminal bouton(GO:0043195)
0.1 0.8 GO:0002142 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.1 0.8 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 1.7 GO:0031430 M band(GO:0031430)
0.1 0.5 GO:0016589 NURF complex(GO:0016589)
0.1 0.5 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 0.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 1.4 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 0.3 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.4 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 2.9 GO:0031941 filamentous actin(GO:0031941)
0.1 2.1 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 1.0 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.1 2.3 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.9 GO:0098831 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 3.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 3.2 GO:0030141 secretory granule(GO:0030141)
0.0 0.8 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.9 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.3 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.2 GO:0070449 elongin complex(GO:0070449)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 2.7 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.9 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 1.5 GO:0042383 sarcolemma(GO:0042383)
0.0 0.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.1 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.5 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.5 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.1 GO:0031201 SNARE complex(GO:0031201)
0.0 0.5 GO:0043204 perikaryon(GO:0043204)
0.0 0.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.9 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 1.9 GO:0030424 axon(GO:0030424)
0.0 0.9 GO:0043025 neuronal cell body(GO:0043025)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0008397 sterol 12-alpha-hydroxylase activity(GO:0008397)
0.6 3.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.3 2.3 GO:0071916 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.3 2.4 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 2.6 GO:0004568 chitinase activity(GO:0004568)
0.2 0.7 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.2 1.1 GO:0038131 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.2 0.6 GO:0060175 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.2 0.8 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.2 0.6 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 0.6 GO:0097643 amylin receptor activity(GO:0097643)
0.2 1.7 GO:0004359 glutaminase activity(GO:0004359)
0.2 1.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.2 0.9 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 2.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 0.7 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.2 0.7 GO:0072570 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.2 0.8 GO:0031841 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.2 1.3 GO:0004100 chitin synthase activity(GO:0004100)
0.2 3.4 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 2.1 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.1 1.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 1.0 GO:0019809 spermidine binding(GO:0019809)
0.1 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.0 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 1.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 1.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.8 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 3.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.7 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 3.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.4 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 1.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 7.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.3 GO:0004133 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.1 0.5 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 0.4 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 1.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.4 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 0.8 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 1.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.7 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.5 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 0.3 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.3 GO:0043121 neurotrophin binding(GO:0043121)
0.1 0.3 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.2 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.7 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 1.6 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 0.8 GO:0030506 ankyrin binding(GO:0030506)
0.1 1.5 GO:0051787 misfolded protein binding(GO:0051787)
0.1 1.4 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 1.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 5.1 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.5 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.1 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.8 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.9 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.8 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.5 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.8 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.7 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 1.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.4 GO:0042285 xylosyltransferase activity(GO:0042285)
0.0 0.6 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 1.1 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 6.0 GO:0015293 symporter activity(GO:0015293)
0.0 1.0 GO:0008483 transaminase activity(GO:0008483)
0.0 0.9 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.6 GO:0008242 omega peptidase activity(GO:0008242)
0.0 1.2 GO:0017022 myosin binding(GO:0017022)
0.0 0.2 GO:1900750 oligopeptide binding(GO:1900750)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 6.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.2 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 3.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 1.5 GO:0050661 NADP binding(GO:0050661)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.9 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 1.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0031704 apelin receptor binding(GO:0031704)
0.0 0.3 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.6 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.6 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.7 GO:0016866 intramolecular transferase activity(GO:0016866)
0.0 0.4 GO:0003785 actin monomer binding(GO:0003785)
0.0 2.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.9 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 5.6 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.7 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 1.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.6 GO:0005178 integrin binding(GO:0005178)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 3.1 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 0.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 1.1 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 1.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.4 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.6 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.7 PID AURORA B PATHWAY Aurora B signaling
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.6 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.5 PID FOXO PATHWAY FoxO family signaling
0.0 0.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.2 PID ARF 3PATHWAY Arf1 pathway
0.0 0.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.3 0.9 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.2 2.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 1.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 1.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 0.7 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.1 0.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 2.1 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.4 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.9 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.5 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.6 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 1.7 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.1 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.9 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.2 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.0 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.2 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism