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PRJEB1986: zebrafish developmental stages transcriptome

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Results for smad3a+smad3b

Z-value: 0.73

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Transcription factors associated with smad3a+smad3b

Gene Symbol Gene ID Gene Info
ENSDARG00000010207 SMAD family member 3b
ENSDARG00000036096 SMAD family member 3a
ENSDARG00000117146 SMAD family member 3a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
smad3bdr11_v1_chr18_+_19772874_19772874-0.615.1e-03Click!
smad3adr11_v1_chr7_-_34149263_34149263-0.223.7e-01Click!

Activity profile of smad3a+smad3b motif

Sorted Z-values of smad3a+smad3b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_16949391 3.23 ENSDART00000152635
zgc:174153
chr5_+_24305877 3.14 ENSDART00000144226
cathepsin L, like
chr3_-_58644920 1.61 ENSDART00000155953
dehydrogenase/reductase (SDR family) member 7Ca
chr21_+_20903244 1.53 ENSDART00000186193
complement component 7b
chr5_+_22459087 1.49 ENSDART00000134781

chr2_-_20599315 1.44 ENSDART00000114199
si:ch211-267e7.3
chr12_-_21681509 1.39 ENSDART00000112726
essential meiotic structure-specific endonuclease 1
chr8_-_13541514 1.38 ENSDART00000063834
zgc:86586
chr4_+_15944245 1.34 ENSDART00000134594
si:dkey-117n7.3
chr1_+_47178529 1.10 ENSDART00000158432
ENSDART00000074450
ENSDART00000137448
MORC family CW-type zinc finger 3b
chr8_-_37043900 1.09 ENSDART00000139567
renin binding protein
chr25_-_35956344 1.07 ENSDART00000066987
M-phase phosphoprotein 6
chr8_-_13735572 0.98 ENSDART00000139642
si:dkey-258f14.7
chr13_+_10023256 0.96 ENSDART00000110035
S1 RNA binding domain 1
chr2_-_59265521 0.95 ENSDART00000146341
ENSDART00000097799
finTRIM family, member 33
chr4_-_64141714 0.94 ENSDART00000128628

chr3_-_9444749 0.94 ENSDART00000182191

chr19_-_10207103 0.92 ENSDART00000151629
zinc finger protein 865
chr9_-_41153896 0.92 ENSDART00000059667
WD repeat domain 75
chr3_-_28872756 0.92 ENSDART00000138840
eukaryotic elongation factor 2 lysine methyltransferase
chr4_-_11577253 0.91 ENSDART00000144452
neuroepithelial cell transforming 1
chr22_+_14836291 0.90 ENSDART00000122740
GTP binding protein 1, like
chr1_+_21731382 0.90 ENSDART00000054395
paired box 5
chr25_-_16552135 0.90 ENSDART00000125836
si:ch211-266k8.4
chr11_+_25010491 0.85 ENSDART00000167285
zgc:92107
chr23_-_21463788 0.82 ENSDART00000079265
hairy-related 4, tandem duplicate 4
chr10_+_8875195 0.82 ENSDART00000141045
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 3
chr9_-_7378566 0.82 ENSDART00000144003
solute carrier family 23, member 3
chr2_-_59157790 0.78 ENSDART00000192303
ENSDART00000159362
finTRIM family, member 32
chr24_+_9744012 0.78 ENSDART00000129656
transmembrane protein 108
chr13_-_21650404 0.77 ENSDART00000078352
tetraspanin 14
chr14_-_25095808 0.77 ENSDART00000184244
matrin 3-like 1.1
chr3_+_13603272 0.76 ENSDART00000185084
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr4_-_30440116 0.73 ENSDART00000159935
si:dkey-199m13.5
chr12_-_17479078 0.70 ENSDART00000079115
3'-phosphoadenosine 5'-phosphosulfate synthase 2b
chr3_-_10779777 0.69 ENSDART00000153911
zinc finger protein 1004
chr1_-_52494122 0.68 ENSDART00000131407
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr19_-_8962884 0.68 ENSDART00000172582
ENSDART00000104657
mitochondrial ribosomal protein S21
chr16_+_26706519 0.68 ENSDART00000142706
vir like m6A methyltransferase associated
chr20_+_35282682 0.67 ENSDART00000187199
family with sequence similarity 49, member A
chr21_-_26071773 0.66 ENSDART00000141382
RAB34, member RAS oncogene family b
chr20_-_2619316 0.66 ENSDART00000185777
BUB1 mitotic checkpoint serine/threonine kinase
chr13_+_21677767 0.66 ENSDART00000165166
mitochondrial ribosome-associated GTPase 1
chr19_-_15281996 0.66 ENSDART00000103784
endothelin 2
chr19_-_42503143 0.65 ENSDART00000007642
zgc:110239
chr17_-_45386546 0.65 ENSDART00000182647
transmembrane protein 206
chr23_+_21455152 0.65 ENSDART00000158511
ENSDART00000161321
ENSDART00000160731
ENSDART00000137573
hairy-related 4, tandem duplicate 2
chr25_-_2081371 0.63 ENSDART00000104915
ENSDART00000156925
wingless-type MMTV integration site family, member 7Bb
chr4_-_25812329 0.63 ENSDART00000146658
transmembrane and coiled-coil domain family 3
chr1_-_57172294 0.63 ENSDART00000063774
Rac family small GTPase 1, like
chr2_-_59376399 0.62 ENSDART00000137134
finTRIM family, member 38
chr5_-_31857593 0.61 ENSDART00000191650
ENSDART00000183731
protein kinase N3
chr1_-_59130383 0.61 ENSDART00000171552

chr22_+_36582963 0.60 ENSDART00000132181
armadillo repeat containing 9
chr19_+_627899 0.59 ENSDART00000148508
telomerase reverse transcriptase
chr16_-_32204470 0.59 ENSDART00000143928
RWD domain containing 1
chr6_-_43283122 0.58 ENSDART00000186022
FERM domain containing 4Ba
chr16_-_32006737 0.57 ENSDART00000184813
ENSDART00000179827
glutathione S-transferase kappa 4
chr5_+_62723233 0.57 ENSDART00000183718
nanos homolog 2
chr20_+_25711718 0.56 ENSDART00000033436
centrosomal protein 135
chr16_+_15114645 0.56 ENSDART00000158483
MDM2 binding protein
chr17_-_27273296 0.55 ENSDART00000077087
inhibitor of DNA binding 3
chr6_+_37623693 0.55 ENSDART00000144812
ENSDART00000182709
tubulin, gamma complex associated protein 5
chr5_+_4806851 0.55 ENSDART00000067599
angiopoietin-like 2a
chr6_-_8498676 0.54 ENSDART00000148627
peptidoglycan recognition protein 2
chr13_+_33298338 0.54 ENSDART00000131892
ENSDART00000143895
IQ motif containing C
chr7_-_58244220 0.52 ENSDART00000180450
un-named hu7910
chr5_-_15283509 0.51 ENSDART00000052712
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
chr5_+_13394543 0.51 ENSDART00000051669
ENSDART00000135921
tectonic family member 2
chr22_-_17499513 0.51 ENSDART00000105460
si:ch211-197g15.6
chr12_+_27061720 0.50 ENSDART00000153426
Snf2-related CREBBP activator protein
chr14_+_38786298 0.49 ENSDART00000164440
si:ch211-195b11.3
chr11_+_30306606 0.49 ENSDART00000128276
ENSDART00000190222
UDP glucuronosyltransferase 1 family, polypeptide B4
chr23_+_13928346 0.49 ENSDART00000155326
si:dkey-90a13.10
chr16_+_14249546 0.49 ENSDART00000059967
polymerase (RNA) III (DNA directed) polypeptide C
chr25_-_29415369 0.48 ENSDART00000110774
ENSDART00000019183
UDP glucuronosyltransferase 5 family, polypeptide A2
UDP glucuronosyltransferase 5 family, polypeptide A1
chr11_+_45448212 0.45 ENSDART00000173341
son of sevenless homolog 1 (Drosophila)
chr3_+_34120191 0.45 ENSDART00000020017
ENSDART00000151700
aldehyde dehydrogenase 3 family, member B1
chr3_-_4501026 0.45 ENSDART00000163052
zgc:162198
chr7_+_21180747 0.45 ENSDART00000185543
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr5_-_24124118 0.45 ENSDART00000051550
capping protein (actin filament), gelsolin-like a
chr10_+_36441124 0.44 ENSDART00000185626
ubiquitin specific peptidase like 1
chr11_-_23332592 0.43 ENSDART00000125024
golgi transport 1A
chr21_-_27362938 0.43 ENSDART00000131297
Ras and Rab interactor 1a
chr5_+_33488860 0.43 ENSDART00000135571
si:dkey-238j22.1
chr18_+_50961953 0.42 ENSDART00000158768
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
chr19_-_438337 0.42 ENSDART00000127985
mitochondrial transcription termination factor 1
chr17_+_10578823 0.42 ENSDART00000134610
MGA, MAX dimerization protein a
chr11_+_15890984 0.42 ENSDART00000158433
pantothenate kinase 4
chr12_-_3978306 0.42 ENSDART00000149473
ENSDART00000114857
protein phosphatase 4, catalytic subunit b
chr17_-_45386823 0.41 ENSDART00000156002
transmembrane protein 206
chr8_+_25893071 0.41 ENSDART00000078161
transmembrane protein 115
chr12_-_18560500 0.41 ENSDART00000078172
BRICHOS domain containing 5
chr16_-_9449712 0.41 ENSDART00000136522
PRP3 pre-mRNA processing factor 3 homolog (yeast)
chr8_+_50150834 0.40 ENSDART00000056074
ectonucleoside triphosphate diphosphohydrolase 4
chr24_+_29912509 0.40 ENSDART00000168422
ferric-chelate reductase 1b
chr12_-_33805366 0.40 ENSDART00000030566
galactokinase 1
chr23_-_26880623 0.40 ENSDART00000038491
adenylate cyclase 6b
chr20_-_4883673 0.40 ENSDART00000145540
ENSDART00000053877
zinc finger, DHHC-type containing 14
chr21_+_33249478 0.40 ENSDART00000169972
si:ch211-151g22.1
chr14_-_30983011 0.39 ENSDART00000014095
RAP2C, member of RAS oncogene family
chr25_+_36315127 0.39 ENSDART00000191984
zgc:165555
chr4_-_11737939 0.39 ENSDART00000150299
podocalyxin-like
chr22_-_28373698 0.38 ENSDART00000157592
si:ch211-213c4.5
chr4_-_76488581 0.36 ENSDART00000174291
finTRIM family, member 51
chr22_-_10591876 0.36 ENSDART00000105846
si:dkey-42i9.8
chr6_-_8498908 0.36 ENSDART00000149222
peptidoglycan recognition protein 2
chr11_+_30310170 0.36 ENSDART00000127797
UDP glucuronosyltransferase 1 family, polypeptide B3
chr23_-_21453614 0.35 ENSDART00000079274
hairy-related 4, tandem duplicate 1
chr15_-_18218227 0.35 ENSDART00000156332
bloodthirsty-related gene family, member 21
chr13_+_2830574 0.35 ENSDART00000138143
si:ch211-233m11.1
chr11_-_8208464 0.35 ENSDART00000161283
Pim proto-oncogene, serine/threonine kinase, related 203
chr22_+_1526040 0.34 ENSDART00000164089
ENSDART00000159126
si:ch211-255f4.6
chr2_-_59285407 0.34 ENSDART00000181616
finTRIM family, member 34
chr3_-_4591643 0.33 ENSDART00000138144
finTRIM family, member 50
chr23_-_27442544 0.33 ENSDART00000019521
disco-interacting protein 2 homolog Ba
chr16_-_17699111 0.33 ENSDART00000108581
si:dkey-17m8.1
chr24_-_6628359 0.32 ENSDART00000169731
Rho GTPase activating protein 21a
chr20_+_17581881 0.32 ENSDART00000182832
cadherin 2, type 1, N-cadherin (neuronal)
chr7_+_29890292 0.30 ENSDART00000170403
ENSDART00000168600
talin 2a
chr10_+_25982212 0.30 ENSDART00000128292
ENSDART00000108808
Fras1 related extracellular matrix protein 2a
chr5_-_31716713 0.30 ENSDART00000131443
dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
chr25_-_35126024 0.30 ENSDART00000185109
zgc:165555
chr1_-_29761086 0.30 ENSDART00000136760
asparagine-linked glycosylation 11 (alpha-1,2-mannosyltransferase)
chr14_+_2487672 0.29 ENSDART00000170629
ENSDART00000123063
fibroblast growth factor 18a
chr20_-_1454131 0.29 ENSDART00000138059
protein tyrosine phosphatase, receptor type, K
chr7_-_5608678 0.29 ENSDART00000138572
si:ch211-165f21.2
chr8_-_23194408 0.28 ENSDART00000141090
si:ch211-196c10.15
chr9_+_29616854 0.28 ENSDART00000033902
ENSDART00000143493
PHD finger protein 11
chr9_-_41818760 0.28 ENSDART00000140601
si:dkeyp-30e7.2
chr23_-_18567088 0.27 ENSDART00000192371
selenophosphate synthetase 2
chr23_+_36052944 0.27 ENSDART00000103149
homeobox C13a
chr2_+_47927026 0.27 ENSDART00000143023
finTRIM family, member 25
chr10_+_5268054 0.26 ENSDART00000114491
receptor tyrosine kinase-like orphan receptor 2
chr3_+_24190207 0.26 ENSDART00000034762
proline rich 15-like a
chr5_+_17780475 0.26 ENSDART00000110783
ENSDART00000115227
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
chr2_-_7605121 0.25 ENSDART00000182099

chr6_-_39649504 0.25 ENSDART00000179960
ENSDART00000190951
La ribonucleoprotein domain family, member 4Ab
chr4_-_73227710 0.25 ENSDART00000193165

chr18_-_7454422 0.25 ENSDART00000124709
putative pyruvate dehydrogenase phosphatase isoenzyme 2
chr12_+_46386983 0.25 ENSDART00000183982
Danio rerio legumain (LOC100005356), mRNA.
chr9_-_21369765 0.25 ENSDART00000132032
intraflagellar transport 88 homolog
chr9_-_16218097 0.24 ENSDART00000190503
myosin IB
chr5_+_50371509 0.24 ENSDART00000167163
SMC5-SMC6 complex localization factor 1
chr3_-_48980319 0.24 ENSDART00000165319
finTRIM family, member 42
chr22_+_661711 0.23 ENSDART00000113795
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr8_+_23194212 0.23 ENSDART00000028946
ENSDART00000186842
ENSDART00000137815
ENSDART00000136914
ENSDART00000144855
ENSDART00000182689
tumor protein D52-like 2a
chr24_-_17400472 0.23 ENSDART00000024691
cullin 1b
chr1_+_23784905 0.23 ENSDART00000171951
ENSDART00000188521
ENSDART00000183029
ENSDART00000187183
slit homolog 2 (Drosophila)
chr1_-_59139599 0.23 ENSDART00000152233
si:ch1073-110a20.3
chr5_+_63390315 0.22 ENSDART00000124616
RAB14, member RAS oncogene family
chr14_-_40797117 0.22 ENSDART00000122369
E74-like ETS transcription factor 1
chr22_+_8489400 0.21 ENSDART00000129119

chr9_-_16853462 0.21 ENSDART00000160273

chr15_+_38007237 0.21 ENSDART00000182271

chr15_-_25556227 0.21 ENSDART00000156445
matrix metallopeptidase 20a (enamelysin)
chr15_-_41450823 0.20 ENSDART00000183327
NLR family CARD domain containing 9
chr7_-_6100716 0.20 ENSDART00000173003
si:cabz01036006.1
chr21_+_25533908 0.19 ENSDART00000185225
NLR family, CARD domain containing 3-like 1
chr5_+_13385837 0.18 ENSDART00000191190
chemokine (C-C motif) ligand 19a, tandem duplicate 1
chr4_+_16787488 0.18 ENSDART00000143006
golgi transport 1Ba
chr2_+_25560556 0.18 ENSDART00000133623
phospholipase D1a
chr3_-_2091029 0.18 ENSDART00000141464
si:dkey-88j15.4
chr1_-_43920576 0.18 ENSDART00000191914
secretory calcium-binding phosphoprotein 7
chr7_+_24523017 0.18 ENSDART00000077047
bloodthirsty-related gene family, member 9
chr15_-_5203371 0.17 ENSDART00000141582
odorant receptor, family E, subfamily 128, member 8
chr15_+_2500510 0.17 ENSDART00000180329
WD repeat domain 53
chr5_+_38685089 0.17 ENSDART00000139743
si:dkey-58f10.10
chr2_-_47904043 0.16 ENSDART00000185328
ENSDART00000126740
finTRIM family, member 22
chr5_+_71999996 0.16 ENSDART00000179933
ENSDART00000187070
phospholipid phosphatase 7 (inactive)
chr24_-_37698796 0.16 ENSDART00000172178
si:ch211-231f6.6
chr21_-_17603182 0.15 ENSDART00000020048
ENSDART00000177270
gelsolin a
chr23_-_35694461 0.15 ENSDART00000185884
tubulin, alpha 1c
chr22_+_19478140 0.15 ENSDART00000135291
ENSDART00000136576
si:dkey-78l4.8
chr13_-_46899329 0.14 ENSDART00000181699
solute carrier family 29 (equilibrative nucleoside transporter), member 1a
chr18_-_26715655 0.14 ENSDART00000181497
MALT paracaspase 3
chr20_-_29683754 0.14 ENSDART00000130599
ENSDART00000015928
ENSDART00000131219
si:ch211-195d17.2
chr1_-_45889820 0.14 ENSDART00000144735
patatin-like phospholipase domain containing 6
chr21_+_25533531 0.13 ENSDART00000134052
NLR family, CARD domain containing 3-like 1
chr19_-_24218942 0.13 ENSDART00000189198

chr14_-_28052474 0.13 ENSDART00000172948
ENSDART00000135337
si:ch211-220e11.3
zgc:64189
chr8_-_52594111 0.13 ENSDART00000167667
si:ch73-199g24.2
chr8_-_38201415 0.13 ENSDART00000155189
PDZ and LIM domain 2 (mystique)
chr1_-_57129179 0.13 ENSDART00000157226
ENSDART00000152469
si:ch73-94k4.2
chr23_-_2099350 0.13 ENSDART00000091532
neuron-derived neurotrophic factor
chr18_-_33093705 0.12 ENSDART00000059500
olfactory receptor C family, d3
chr13_+_17694845 0.12 ENSDART00000079778
interferon-induced protein with tetratricopeptide repeats 8
chr1_-_59104145 0.12 ENSDART00000132495
ENSDART00000152457
si:zfos-2330d3.1
si:zfos-2330d3.7
chr22_+_661505 0.12 ENSDART00000149460
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr16_+_30961822 0.11 ENSDART00000059187
glutathione S-transferase kappa 2
chr10_+_17088261 0.11 ENSDART00000132103
si:dkey-106l3.7
chr6_+_49926115 0.11 ENSDART00000018523
adenosylhomocysteinase
chr19_+_38168006 0.11 ENSDART00000087662
ENSDART00000177759
PHD finger protein 14
chr15_-_37834433 0.09 ENSDART00000189748
si:dkey-238d18.3
chr4_+_33654247 0.09 ENSDART00000192537
si:dkey-84h14.1
chr4_+_35576329 0.09 ENSDART00000171191
ENSDART00000161611
si:dkeyp-4c4.2
chr22_+_14836040 0.09 ENSDART00000180951
GTP binding protein 1, like
chr2_+_42318012 0.09 ENSDART00000138137
finTRIM family, member 8
chr10_-_40490647 0.09 ENSDART00000143660
trace amine associated receptor 20x
chr7_-_1504382 0.09 ENSDART00000172770
si:zfos-405g10.4

Network of associatons between targets according to the STRING database.

First level regulatory network of smad3a+smad3b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0098543 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.2 0.7 GO:0050427 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.2 0.6 GO:0007571 age-dependent general metabolic decline(GO:0007571)
0.2 1.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.6 GO:0032534 regulation of microvillus organization(GO:0032530) regulation of microvillus assembly(GO:0032534)
0.1 0.4 GO:0009193 ribonucleoside diphosphate catabolic process(GO:0009191) pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.1 0.7 GO:0060584 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 1.4 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.1 0.3 GO:0021577 hindbrain structural organization(GO:0021577) dorsal fin morphogenesis(GO:0035142) cell motility involved in somitogenic axis elongation(GO:0090247) cell migration involved in somitogenic axis elongation(GO:0090248)
0.1 0.5 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.9 GO:0060005 reflex(GO:0060004) vestibular reflex(GO:0060005) vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.1 0.8 GO:0097106 postsynaptic density organization(GO:0097106)
0.1 0.6 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.7 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 0.4 GO:0030575 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576) protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.1 0.7 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 0.2 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
0.1 1.8 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 0.2 GO:0007414 axonal defasciculation(GO:0007414)
0.1 0.2 GO:1904184 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.1 0.3 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.4 GO:0006012 galactose metabolic process(GO:0006012)
0.1 0.6 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.1 0.2 GO:0090386 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.1 0.6 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.1 1.5 GO:0019835 cytolysis(GO:0019835)
0.1 0.9 GO:1900107 regulation of nodal signaling pathway(GO:1900107)
0.0 0.5 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.4 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.3 GO:2000758 positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.7 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.0 0.1 GO:0021795 pallium development(GO:0021543) cerebral cortex cell migration(GO:0021795) cerebral cortex tangential migration(GO:0021800) cerebral cortex tangential migration using cell-axon interactions(GO:0021824) substrate-dependent cerebral cortex tangential migration(GO:0021825) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) cerebral cortex development(GO:0021987)
0.0 1.1 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.4 GO:0033866 nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0 0.8 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.6 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.1 GO:0015864 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.0 0.6 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.3 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 1.0 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.5 GO:0043486 histone exchange(GO:0043486)
0.0 0.6 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.4 GO:0022011 myelination in peripheral nervous system(GO:0022011)
0.0 0.7 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.2 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 0.3 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.2 0.6 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 0.6 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 0.3 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 1.5 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.5 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.4 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 0.7 GO:0000780 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.3 GO:0014704 intercalated disc(GO:0014704)
0.0 0.4 GO:0015030 Cajal body(GO:0015030)
0.0 6.8 GO:0005764 lysosome(GO:0005764)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.6 GO:0005844 polysome(GO:0005844)
0.0 0.4 GO:0071141 SMAD protein complex(GO:0071141)
0.0 1.4 GO:0005814 centriole(GO:0005814)
0.0 0.4 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.6 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.2 GO:0005903 brush border(GO:0005903)
0.0 0.4 GO:0055038 recycling endosome membrane(GO:0055038)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.2 0.7 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.2 0.6 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.1 0.7 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.5 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.3 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.1 0.4 GO:0032183 SUMO binding(GO:0032183)
0.1 0.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.4 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.7 GO:0004046 aminoacylase activity(GO:0004046)
0.1 1.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 7.2 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.5 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.3 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.0 1.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.6 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.5 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.9 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.2 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.0 GO:0001607 neuromedin U receptor activity(GO:0001607)
0.0 0.4 GO:0019003 GDP binding(GO:0019003)
0.0 0.4 GO:0019200 carbohydrate kinase activity(GO:0019200)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.7 PID AURORA B PATHWAY Aurora B signaling
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.7 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.9 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.3 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.6 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.1 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway