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PRJEB1986: zebrafish developmental stages transcriptome

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Results for smad2_smad10a+smad4a_smad1

Z-value: 1.36

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Transcription factors associated with smad2_smad10a+smad4a_smad1

Gene Symbol Gene ID Gene Info
ENSDARG00000006389 SMAD family member 2
ENSDARG00000045094 si_dkey-222b8.1
ENSDARG00000070428 si_dkey-222b8.1
ENSDARG00000075226 SMAD family member 4a
ENSDARG00000027199 SMAD family member 1
ENSDARG00000112617 SMAD family member 1
ENSDARG00000115674 SMAD family member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
smad2dr11_v1_chr10_-_14920989_149209890.796.1e-05Click!
si:dkey-239n17.4dr11_v1_chr16_-_28876479_288764790.493.1e-02Click!
si:dkey-222b8.1dr11_v1_chr19_+_23932259_239322590.436.9e-02Click!
smad4adr11_v1_chr10_+_585719_5857190.292.3e-01Click!
smad1dr11_v1_chr1_-_35916247_359162470.262.9e-01Click!

Activity profile of smad2_smad10a+smad4a_smad1 motif

Sorted Z-values of smad2_smad10a+smad4a_smad1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_46040618 4.73 ENSDART00000161415

chr13_-_479129 2.72 ENSDART00000159803
ENSDART00000082127
HEAT repeat containing 5B
chr20_-_7648325 2.25 ENSDART00000186541

chr23_+_36460239 2.17 ENSDART00000172441
LIM domain and actin binding 1a
chr9_-_180334 1.97 ENSDART00000180339
zgc:158619
chr2_+_54755172 1.89 ENSDART00000097864
ankyrin repeat domain 12
chr3_-_3496738 1.84 ENSDART00000186849

chr14_+_8127893 1.73 ENSDART00000169091
pleckstrin and Sec7 domain containing 2
chr5_-_66028714 1.73 ENSDART00000022625
ENSDART00000164228
NOTCH regulated ankyrin repeat protein b
chr13_-_5079511 1.59 ENSDART00000110248
solute carrier family 29 (equilibrative nucleoside transporter), member 3
chr25_+_31958911 1.56 ENSDART00000191394
ENSDART00000090727
ENSDART00000185893
dual oxidase
chr22_+_635813 1.50 ENSDART00000179067

chr18_+_50461981 1.44 ENSDART00000158761

chr10_-_10018794 1.26 ENSDART00000130734
spermatid perinuclear RNA binding protein
chr14_-_237130 1.25 ENSDART00000164988
biorientation of chromosomes in cell division 1-like 1
chr8_+_32719930 1.17 ENSDART00000145362
hemicentin 2
chr20_+_35085224 1.14 ENSDART00000040456
CDC42 binding protein kinase alpha (DMPK-like) b
chr23_+_41831224 1.10 ENSDART00000171885
sterol carrier protein 2b
chr6_-_31827597 1.07 ENSDART00000159400
receptor tyrosine kinase-like orphan receptor 1
chr4_-_76488581 1.05 ENSDART00000174291
finTRIM family, member 51
chr7_-_72269049 1.04 ENSDART00000161497

chr14_+_8442248 1.01 ENSDART00000163059
si:dkey-160o24.3
chr17_+_1514711 0.99 ENSDART00000165641
v-akt murine thymoma viral oncogene homolog 1
chr19_+_41551335 0.99 ENSDART00000169193
si:ch211-57n23.4
chr13_+_25433774 0.96 ENSDART00000141255
si:dkey-51a16.9
chr10_+_37181780 0.95 ENSDART00000187625
kinase suppressor of ras 1a
chr19_+_42219165 0.93 ENSDART00000163192

chr9_+_45605410 0.86 ENSDART00000136444
ENSDART00000007189
ENSDART00000158713
ENSDART00000182671
TNF receptor-associated factor 3 interacting protein 1
chr9_+_52411530 0.86 ENSDART00000163684
NME/NM23 family member 8
chr20_-_48061351 0.80 ENSDART00000164962
prolyl endopeptidase
chr12_-_9294819 0.80 ENSDART00000003805
parathyroid hormone 1 receptor b
chr5_-_58780160 0.75 ENSDART00000166955
Rho guanine nucleotide exchange factor (GEF) 12b
chr19_+_31061718 0.75 ENSDART00000145971
sclerostin domain containing 1b
chr18_+_49225552 0.72 ENSDART00000135026
si:ch211-136a13.1
chr5_+_18047111 0.70 ENSDART00000132164
histone cell cycle regulator a
chr15_+_28303161 0.70 ENSDART00000087926
myosin Ic, paralog b
chr2_-_42628028 0.68 ENSDART00000179866
myosin X
chr18_-_44908479 0.67 ENSDART00000169636
si:ch211-71n6.4
chr23_+_44080382 0.67 ENSDART00000011715
zgc:56304
chr4_-_16412084 0.66 ENSDART00000188460
decorin
chr23_+_40908583 0.64 ENSDART00000180933

chr19_+_25478203 0.64 ENSDART00000132934
collagen, type XXVIII, alpha 1a
chr17_+_45765164 0.62 ENSDART00000145882
asparaginase homolog (S. cerevisiae)
chr17_+_50524573 0.60 ENSDART00000187974

chr11_+_77526 0.59 ENSDART00000193521

chr24_-_26632171 0.57 ENSDART00000008374
ENSDART00000017384
TRAF2 and NCK interacting kinase b
chr16_-_39859119 0.54 ENSDART00000138388
RNA binding motif, single stranded interacting protein
chr22_-_506522 0.54 ENSDART00000106645
ENSDART00000067637
dual serine/threonine and tyrosine protein kinase
chr3_-_1317290 0.53 ENSDART00000047094

chr20_+_18163355 0.52 ENSDART00000011287
aquaporin 4
chr25_+_32157326 0.50 ENSDART00000112588
tight junction protein 1b
chr13_+_22295905 0.49 ENSDART00000180133
ENSDART00000181125
ubiquitin specific peptidase 54a
chr16_-_11961325 0.48 ENSDART00000143845
si:ch73-296e2.3
chr8_+_28527776 0.48 ENSDART00000053782
scratch family zinc finger 2
chr2_+_47623202 0.48 ENSDART00000154465
si:ch211-165b10.3
chr7_-_18508815 0.47 ENSDART00000173539
regulator of G protein signaling 12a
chr25_-_6261693 0.46 ENSDART00000135808
iron-responsive element binding protein 2
chr19_-_18152942 0.44 ENSDART00000190182
nuclear factor, erythroid 2-like 3
chr6_+_6491013 0.43 ENSDART00000140827
B cell CLL/lymphoma 11Ab
chr4_-_76488854 0.42 ENSDART00000132323
finTRIM family, member 51
chr5_+_457729 0.42 ENSDART00000025183
intraflagellar transport 74
chr3_+_13879446 0.41 ENSDART00000164767
phenylalanyl-tRNA synthetase, alpha subunit
chr20_-_26042070 0.41 ENSDART00000140255
si:dkey-12h9.6
chr19_-_47456787 0.41 ENSDART00000168792
transcription factor AP-2 epsilon
chr1_+_57347888 0.41 ENSDART00000104222
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
chr18_-_5542351 0.41 ENSDART00000129459
spermatogenesis associated 5-like 1
chr8_-_2230128 0.41 ENSDART00000140427
si:dkeyp-117b11.2
chr11_+_45255774 0.40 ENSDART00000172838
alveolar soft part sarcoma chromosome region, candidate 1
chr5_-_70625697 0.40 ENSDART00000179538
ENSDART00000190540

chr25_-_210730 0.40 ENSDART00000187580

chr4_-_191736 0.40 ENSDART00000169187
ENSDART00000192054
protein tyrosine phosphatase, receptor type, O
chr18_+_50961953 0.40 ENSDART00000158768
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
chr6_-_52757276 0.39 ENSDART00000159154

chr7_+_26998169 0.38 ENSDART00000128110
ENSDART00000101018
cell cycle associated protein 1a
chr3_-_31019715 0.37 ENSDART00000156687
ENSDART00000156127
ENSDART00000153945
si:dkeyp-71f10.5
chr9_+_51882534 0.37 ENSDART00000165493

chr15_-_40157331 0.36 ENSDART00000187958
si:ch211-281l24.3
chr7_-_29271738 0.35 ENSDART00000109030
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr19_+_41551543 0.35 ENSDART00000112364
si:ch211-57n23.4
chr16_-_30655980 0.34 ENSDART00000146508
low density lipoprotein receptor class A domain containing 4b
chr20_-_2355357 0.34 ENSDART00000085281
si:ch73-18b11.1
chr3_-_53559408 0.34 ENSDART00000073930
notch 3
chr20_-_4049862 0.33 ENSDART00000158057
SprT-like N-terminal domain
chr4_-_21466825 0.33 ENSDART00000066897
PRKC, apoptosis, WT1, regulator
chr23_-_44965582 0.33 ENSDART00000163367
transferrin receptor 2
chr8_+_54055390 0.33 ENSDART00000102696
membrane associated guanylate kinase, WW and PDZ domain containing 1a
chr10_-_35186310 0.33 ENSDART00000127805
POM121 transmembrane nucleoporin
chr22_+_35930526 0.32 ENSDART00000169242

chr13_-_16226312 0.32 ENSDART00000163952
zgc:110045
chr6_+_11989537 0.32 ENSDART00000190817
bromodomain adjacent to zinc finger domain, 2Ba
chr14_-_451555 0.32 ENSDART00000190906
FAT atypical cadherin 4
chr19_-_36675023 0.32 ENSDART00000132471
CUB and Sushi multiple domains 2
chr22_+_38824012 0.32 ENSDART00000144318
ENSDART00000003736
anosmin 1b
chr14_+_6546516 0.32 ENSDART00000097214
ADAM metallopeptidase domain 19b
chr20_+_23625387 0.32 ENSDART00000147945
ENSDART00000150497
palladin, cytoskeletal associated protein
chr19_-_43819582 0.31 ENSDART00000160879
ENSDART00000075902
kelch-like family member 43
chr3_-_53559581 0.30 ENSDART00000183499
notch 3
chr12_-_628024 0.30 ENSDART00000158563
ENSDART00000152612
wu:fj29h11
si:ch73-301j1.1
chr20_+_52442870 0.30 ENSDART00000163100
Rho GTPase activating protein 39
chr12_+_48581588 0.30 ENSDART00000114996

chr23_-_27152866 0.30 ENSDART00000141305
si:dkey-157g16.6
chr15_-_40157513 0.29 ENSDART00000184014
si:ch211-281l24.3
chr1_+_47446032 0.29 ENSDART00000126904
ENSDART00000007262
gap junction protein alpha 8 paralog b
chr5_-_66749535 0.29 ENSDART00000132183
K(lysine) acetyltransferase 5b
chr1_+_47585700 0.29 ENSDART00000153746
ENSDART00000084457
SH3 and PX domains 2Aa
chr12_+_17933775 0.29 ENSDART00000186047
ENSDART00000160586
transformation/transcription domain-associated protein
chr19_+_4061699 0.29 ENSDART00000158309
ENSDART00000166512
bloodthirsty-related gene family, member 25
bloodthirsty-related gene family, member 26
chr17_+_10578823 0.29 ENSDART00000134610
MGA, MAX dimerization protein a
chr9_+_34148714 0.29 ENSDART00000078051
G protein-coupled receptor 161
chr19_-_13286722 0.28 ENSDART00000168296
ENSDART00000158330
zinc finger protein, FOG family member 2b
chr25_+_32496723 0.28 ENSDART00000087978
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2a
chr4_+_41602 0.28 ENSDART00000159640
putative homeodomain transcription factor 2
chr20_+_54356540 0.28 ENSDART00000143591
zinc finger protein 410
chr18_+_50924556 0.28 ENSDART00000159287
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr13_+_12175724 0.28 ENSDART00000166053
gamma-aminobutyric acid type A receptor gamma1 subunit
chr15_+_45595385 0.28 ENSDART00000161937
ENSDART00000170214
ENSDART00000157450
ATG16 autophagy related 16-like 1 (S. cerevisiae)
chr21_-_45728069 0.28 ENSDART00000185101

chr1_-_51157660 0.27 ENSDART00000137172
jagged 1a
chr9_-_22963897 0.27 ENSDART00000133676
si:dkey-91i10.2
chr23_+_45734011 0.27 ENSDART00000062415

chr12_+_33403694 0.27 ENSDART00000124083
fatty acid synthase
chr19_-_38611814 0.27 ENSDART00000151958
collagen, type XVI, alpha 1
chr24_+_38306010 0.27 ENSDART00000143184
myosin binding protein C, fast type b
chr2_-_42705284 0.27 ENSDART00000187160
myosin X
chr11_-_44999858 0.27 ENSDART00000167759
ENSDART00000126845
LIM-domain binding 1b
chr17_+_6467398 0.27 ENSDART00000149527
si:dkey-36g24.3
chr17_-_608857 0.27 ENSDART00000163431
kelch like family member 28
chr5_-_41638039 0.27 ENSDART00000144525
ectopic P-granules autophagy protein 5 homolog (C. elegans)
chr14_-_22390821 0.27 ENSDART00000054396
F-box and leucine-rich repeat protein 3, like
chr23_+_4362463 0.26 ENSDART00000039829
zgc:112175
chr12_+_30789611 0.26 ENSDART00000181501
aldehyde dehydrogenase 18 family, member A1
chr1_-_55238610 0.26 ENSDART00000110818

chr18_+_27337994 0.26 ENSDART00000136172
si:dkey-29p10.4
chr18_+_5549672 0.26 ENSDART00000184970
nicotinamide nucleotide transhydrogenase 2
chr1_-_54765262 0.26 ENSDART00000150362
si:ch211-197k17.3
chr5_+_483965 0.26 ENSDART00000150007
TEK tyrosine kinase, endothelial
chr19_-_3754327 0.25 ENSDART00000168463
bloodthirsty-related gene family, member 21
chr25_+_32496877 0.25 ENSDART00000132698
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2a
chr12_+_48511605 0.25 ENSDART00000168389
Rho GTPase activating protein 44
chr7_+_16352924 0.25 ENSDART00000158972
metallophosphoesterase domain containing 2a
chr7_-_25895189 0.25 ENSDART00000173599
ENSDART00000079235
ENSDART00000173786
ENSDART00000173602
ENSDART00000079245
ENSDART00000187568
ENSDART00000173505
CD99 molecule-like 2
chr14_-_1949277 0.25 ENSDART00000159435
protocadherin 2 gamma 5
chr1_-_44037843 0.24 ENSDART00000160276
si:ch73-109d9.3
chr13_+_45980163 0.24 ENSDART00000074547
ENSDART00000005195
BSD domain containing 1
chr24_+_41610068 0.24 ENSDART00000159507

chr10_+_37182626 0.24 ENSDART00000137636
kinase suppressor of ras 1a
chr4_-_29753895 0.24 ENSDART00000150742
si:dkey-191j3.1
chr17_+_24843401 0.24 ENSDART00000110179
connexin 34.4
chr5_+_36752943 0.24 ENSDART00000017138
exocyst complex component 3-like 2a
chr1_-_59411901 0.24 ENSDART00000167015
si:ch211-188p14.4
chr13_+_38302665 0.24 ENSDART00000145777
adhesion G protein-coupled receptor B3
chr6_+_9793495 0.24 ENSDART00000108524
amyotrophic lateral sclerosis 2b (juvenile)
chr13_-_36418921 0.24 ENSDART00000135804
ddb1 and cul4 associated factor 5
chr4_+_77740228 0.24 ENSDART00000193397
si:zfos-2131b9.2
chr25_+_37268900 0.24 ENSDART00000156737
si:dkey-234i14.6
chr2_+_26179096 0.23 ENSDART00000024662
phospholipid phosphatase related 3a
chr3_-_32320537 0.23 ENSDART00000113550
ENSDART00000168483
si:dkey-16p21.7
chr24_-_37272116 0.23 ENSDART00000022999
ubiquitin-conjugating enzyme E2Ib
chr10_+_42589391 0.23 ENSDART00000067689
ENSDART00000075259
fibroblast growth factor receptor 1b
chr12_+_45060789 0.23 ENSDART00000190396
ADAM metallopeptidase domain 12
chr21_+_10828828 0.23 ENSDART00000136449
O-acyltransferase like
chr7_+_36898622 0.23 ENSDART00000190773
TOX high mobility group box family member 3
chr19_+_25497541 0.23 ENSDART00000144300
collagen, type XXVIII, alpha 1a
chr25_-_31433512 0.22 ENSDART00000067028
zgc:172145
chr10_-_74408 0.22 ENSDART00000100073
ENSDART00000141723
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, a
chr21_+_26390549 0.22 ENSDART00000185643
thymosin, beta
chr14_-_30050 0.22 ENSDART00000164411
zinc finger and BTB domain containing 49
chr23_+_3594171 0.22 ENSDART00000159609
si:dkey-9l20.3
chr5_+_8964926 0.22 ENSDART00000091397
ENSDART00000164535
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase b
chr23_+_44633858 0.22 ENSDART00000180728
si:ch73-265d7.2
chr2_+_19236677 0.22 ENSDART00000166292
coiled-coil and C2 domain containing 1B
chr3_-_21288202 0.21 ENSDART00000191766
ENSDART00000187319
family with sequence similarity 171, member A2a
chr18_+_6054816 0.21 ENSDART00000113668
si:ch73-386h18.1
chr4_+_4889257 0.21 ENSDART00000175651
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr20_+_50061890 0.21 ENSDART00000137725
cleavage and polyadenylation specific factor 2
chr21_-_41588129 0.21 ENSDART00000164125
creb3 regulatory factor
chr10_+_44581378 0.21 ENSDART00000190331
seizure related 6 homolog (mouse)-like
chr19_-_81851 0.21 ENSDART00000172319
heterogeneous nuclear ribonucleoprotein R
chr3_+_24458899 0.21 ENSDART00000156655
chromobox homolog 6b
chr3_-_38783951 0.20 ENSDART00000155518
zinc finger protein 281a
chr18_+_18612388 0.20 ENSDART00000186455
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr4_+_31259 0.20 ENSDART00000166826
putative homeodomain transcription factor 2
chr10_+_1052591 0.20 ENSDART00000123405
unc-5 netrin receptor C
chr4_+_11458078 0.20 ENSDART00000037600
ankyrin repeat domain 16
chr4_+_76957765 0.20 ENSDART00000129607
si:dkey-240n22.6
chr6_-_55958705 0.20 ENSDART00000155963
EYA transcriptional coactivator and phosphatase 2
chr19_-_42503143 0.20 ENSDART00000007642
zgc:110239
chr21_+_10866421 0.20 ENSDART00000137858
alpha-kinase 2
chr25_-_31396479 0.20 ENSDART00000156828
proline rich 33
chr4_-_25858620 0.20 ENSDART00000128968
nuclear receptor subfamily 2, group C, member 1
chr19_+_42754882 0.20 ENSDART00000133711
cytoplasmic linker associated protein 2
chr18_+_6706140 0.20 ENSDART00000111343
lipase maturation factor 2a
chr23_-_874418 0.20 ENSDART00000133906
RNA binding motif protein 10
chr19_-_48010490 0.20 ENSDART00000159938
zgc:158376
chr10_-_300000 0.20 ENSDART00000183273
EMSY BRCA2-interacting transcriptional repressor
chr20_-_1265562 0.20 ENSDART00000189866
large tumor suppressor kinase 1
chr10_-_44341288 0.20 ENSDART00000166131
zinc finger, SWIM-type containing 6
chr20_+_44582318 0.19 ENSDART00000149000
ENSDART00000149775
ENSDART00000085416
ATPase family, AAA domain containing 2B
chr23_+_3602779 0.19 ENSDART00000013629
si:dkey-9l20.3
chr9_+_12907574 0.19 ENSDART00000102348
si:dkey-230p4.1

Network of associatons between targets according to the STRING database.

First level regulatory network of smad2_smad10a+smad4a_smad1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0006590 thyroid hormone generation(GO:0006590)
0.2 1.1 GO:0032370 positive regulation of lipid transport(GO:0032370)
0.2 0.6 GO:0035019 somatic stem cell population maintenance(GO:0035019) symmetric cell division(GO:0098725)
0.2 0.6 GO:0016264 gap junction assembly(GO:0016264)
0.2 1.2 GO:0090497 mesenchymal cell migration(GO:0090497)
0.2 1.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.2 1.8 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.4 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.4 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.1 0.9 GO:0031113 regulation of microtubule polymerization(GO:0031113) cerebrospinal fluid circulation(GO:0090660)
0.1 1.6 GO:1901642 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.1 0.4 GO:0072512 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.1 0.6 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.4 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 1.7 GO:0030537 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.1 0.5 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 0.1 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.3 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.9 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.5 GO:0060036 notochord cell vacuolation(GO:0060036)
0.1 0.7 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.1 0.2 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.1 0.5 GO:0006833 water transport(GO:0006833)
0.1 0.3 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.3 GO:0019079 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.1 0.2 GO:0032206 positive regulation of telomere maintenance(GO:0032206) regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
0.1 0.3 GO:0090527 actin filament reorganization(GO:0090527)
0.1 1.4 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.1 0.3 GO:0032616 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.0 0.3 GO:0060251 regulation of glial cell proliferation(GO:0060251)
0.0 0.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.2 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 2.8 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 1.8 GO:0009395 phospholipid catabolic process(GO:0009395)
0.0 0.2 GO:0090386 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.0 0.1 GO:1903441 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.0 0.2 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.5 GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043516)
0.0 0.2 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.2 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591)
0.0 0.2 GO:1902837 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.0 0.3 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.4 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.0 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
0.0 0.2 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.0 0.1 GO:0006290 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:1902895 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis.(GO:0002926)
0.0 0.1 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.3 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.1 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.0 0.5 GO:0070672 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.0 0.1 GO:0002568 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.0 0.2 GO:0034333 adherens junction assembly(GO:0034333)
0.0 1.5 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.2 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.4 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.0 0.2 GO:1902267 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.1 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.9 GO:0050654 chondroitin sulfate proteoglycan metabolic process(GO:0050654)
0.0 2.1 GO:0051017 actin filament bundle assembly(GO:0051017)
0.0 0.2 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.1 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.1 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 0.2 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0009098 leucine biosynthetic process(GO:0009098)
0.0 0.2 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.3 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.1 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.0 0.0 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.0 1.1 GO:0008643 carbohydrate transport(GO:0008643)
0.0 0.1 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.2 GO:0016576 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.5 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.8 GO:1903844 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.0 0.1 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 1.1 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.2 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.1 GO:0061511 centriole elongation(GO:0061511)
0.0 0.1 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.1 GO:0086091 regulation of heart rate by cardiac conduction(GO:0086091)
0.0 0.2 GO:0003139 secondary heart field specification(GO:0003139)
0.0 0.1 GO:0003232 bulbus arteriosus development(GO:0003232)
0.0 0.8 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.1 GO:0090311 regulation of histone deacetylation(GO:0031063) regulation of protein deacetylation(GO:0090311)
0.0 0.1 GO:0072149 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0006266 DNA ligation(GO:0006266) DNA ligation involved in DNA repair(GO:0051103)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.2 GO:0001709 cell fate determination(GO:0001709)
0.0 0.1 GO:0008584 male gonad development(GO:0008584)
0.0 0.1 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045)
0.0 0.3 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0061011 hepatic duct development(GO:0061011)
0.0 0.5 GO:0021587 cerebellum morphogenesis(GO:0021587)
0.0 0.1 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 0.2 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.0 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.2 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.3 GO:0030878 thyroid gland development(GO:0030878)
0.0 0.2 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:1901985 positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.0 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.0 0.3 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.4 GO:0048920 neuromast primordium migration(GO:0048883) posterior lateral line neuromast primordium migration(GO:0048920)
0.0 0.3 GO:0035675 neuromast hair cell development(GO:0035675)
0.0 0.1 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:2000142 regulation of transcription initiation from RNA polymerase II promoter(GO:0060260) regulation of DNA-templated transcription, initiation(GO:2000142)
0.0 0.1 GO:0001765 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.3 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.0 0.2 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.0 0.1 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.0 0.1 GO:0048886 neuromast hair cell differentiation(GO:0048886)
0.0 0.1 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.1 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.1 GO:0002320 lymphoid progenitor cell differentiation(GO:0002320)
0.0 0.1 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.0 GO:0042044 fluid transport(GO:0042044)
0.0 0.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.3 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.0 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0010456 cell proliferation in dorsal spinal cord(GO:0010456)
0.0 0.2 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.0 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.2 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.3 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.1 GO:0019427 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.0 0.0 GO:0051876 pigment granule dispersal(GO:0051876)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.0 GO:0003403 optic vesicle formation(GO:0003403)
0.0 0.1 GO:1901998 toxin transport(GO:1901998)
0.0 0.1 GO:0009648 photoperiodism(GO:0009648)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 1.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.3 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 1.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 2.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 2.9 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.1 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.1 GO:0098826 endoplasmic reticulum tubular network membrane(GO:0098826)
0.0 0.6 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.1 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.0 0.2 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.1 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.0 0.1 GO:0008352 katanin complex(GO:0008352)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 1.3 GO:0042641 actomyosin(GO:0042641)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.3 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.0 GO:0031213 RSF complex(GO:0031213)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.7 GO:0005902 microvillus(GO:0005902)
0.0 0.3 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 1.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.3 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0016586 RSC complex(GO:0016586)
0.0 0.1 GO:0071565 nBAF complex(GO:0071565)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.0 GO:0098753 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) anchored component of the cytoplasmic side of the plasma membrane(GO:0098753)
0.0 0.2 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 1.5 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.0 GO:0005913 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.0 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.3 GO:0008278 cohesin complex(GO:0008278)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.2 0.5 GO:0003994 aconitate hydratase activity(GO:0003994)
0.1 0.5 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.6 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.4 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 0.8 GO:0036122 BMP binding(GO:0036122)
0.1 0.4 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 1.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 0.6 GO:0004067 asparaginase activity(GO:0004067)
0.1 0.3 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.9 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.2 GO:0043621 protein self-association(GO:0043621)
0.1 0.3 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 0.2 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 0.5 GO:0015250 water channel activity(GO:0015250)
0.1 0.3 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.7 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0032138 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.0 0.1 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.0 1.0 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.8 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0031704 apelin receptor binding(GO:0031704)
0.0 0.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0002054 nucleobase binding(GO:0002054)
0.0 0.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 1.8 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.5 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 1.4 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 1.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
0.0 0.3 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.1 GO:0004557 alpha-galactosidase activity(GO:0004557)
0.0 0.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 2.1 GO:0004620 phospholipase activity(GO:0004620)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0043998 H2A histone acetyltransferase activity(GO:0043998)
0.0 0.0 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.7 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.0 GO:0043185 vascular endothelial growth factor receptor 3 binding(GO:0043185)
0.0 0.1 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.5 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.8 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.0 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.6 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.0 GO:0048030 disaccharide binding(GO:0048030)
0.0 0.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.4 GO:0031490 chromatin DNA binding(GO:0031490)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.1 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.7 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.2 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 1.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 0.6 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 0.1 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.1 0.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.2 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 1.2 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME CD28 CO STIMULATION Genes involved in CD28 co-stimulation
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.5 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.1 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.1 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.1 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.0 0.1 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism