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PRJEB1986: zebrafish developmental stages transcriptome

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Results for scrt1a+scrt1b+scrt2

Z-value: 0.91

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Transcription factors associated with scrt1a+scrt1b+scrt2

Gene Symbol Gene ID Gene Info
ENSDARG00000040214 scratch family zinc finger 1b
ENSDARG00000056175 scratch family zinc finger 2
ENSDARG00000100821 scratch family zinc finger 1a
ENSDARG00000110984 scratch family zinc finger 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
scrt1bdr11_v1_chr16_-_31188715_31188715-0.821.7e-05Click!
scrt1adr11_v1_chr19_+_1184878_1184878-0.541.8e-02Click!
scrt2dr11_v1_chr8_+_28527776_28527776-0.194.5e-01Click!

Activity profile of scrt1a+scrt1b+scrt2 motif

Sorted Z-values of scrt1a+scrt1b+scrt2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_36477481 2.45 ENSDART00000128245
low density lipoprotein receptor class A domain containing 2
chr8_-_13985032 2.21 ENSDART00000140576
insulin-like growth factor 3
chr7_-_54677143 2.20 ENSDART00000163748
cyclin D1
chr13_-_28688104 2.18 ENSDART00000133827
polycomb group ring finger 6
chr16_+_5678071 2.03 ENSDART00000011166
ENSDART00000134198
ENSDART00000131575
zgc:158689
chr8_-_1051438 2.01 ENSDART00000067093
ENSDART00000170737
SET and MYND domain containing 1b
chr10_+_31809226 1.86 ENSDART00000087898
forkhead box O1 b
chr5_-_24201437 1.86 ENSDART00000114113
SRY (sex determining region Y)-box 19a
chr3_-_30158395 1.85 ENSDART00000103502
si:ch211-152f23.5
chr25_+_14507567 1.81 ENSDART00000015681
developing brain homeobox 1b
chr20_-_32446406 1.81 ENSDART00000026635
nuclear receptor subfamily 2, group E, member 1
chr8_-_16259063 1.77 ENSDART00000057590
DMRT-like family A2
chr23_-_18130264 1.66 ENSDART00000016976
nuclear casein kinase and cyclin-dependent kinase substrate 1b
chr17_+_23462972 1.56 ENSDART00000112959
ENSDART00000192168
ankyrin repeat domain 1a (cardiac muscle)
chr11_+_14321113 1.51 ENSDART00000039822
ENSDART00000137347
ENSDART00000132997
polypyrimidine tract binding protein 1b
chr21_-_4849029 1.51 ENSDART00000168930
ENSDART00000151019
notch 1a
chr13_-_36844945 1.47 ENSDART00000129562
ENSDART00000150899
ninein (GSK3B interacting protein)
chr14_+_6423973 1.45 ENSDART00000051556
ATP-binding cassette, sub-family A (ABC1), member 1B
chr6_-_52675630 1.39 ENSDART00000083830
syndecan 4
chr2_+_37838259 1.37 ENSDART00000136796
poly (ADP-ribose) polymerase 2
chr16_-_9869056 1.35 ENSDART00000149312
neurocalcin delta a
chr16_-_43233509 1.34 ENSDART00000025877
claudin 12
chr15_+_36309070 1.33 ENSDART00000157034
geminin coiled-coil domain containing
chr25_-_29074064 1.28 ENSDART00000165603
AT rich interactive domain 3B (BRIGHT-like)
chr2_+_10766744 1.27 ENSDART00000015379
growth factor independent 1A transcription repressor a
chr8_-_20118549 1.27 ENSDART00000132218
regulatory factor X, 2 (influences HLA class II expression)
chr23_+_38245610 1.21 ENSDART00000191386
zinc finger protein 217
chr13_+_13578552 1.17 ENSDART00000101673
forkhead box I2
chr25_-_3139805 1.17 ENSDART00000166625
eosinophil peroxidase
chr2_+_25378457 1.17 ENSDART00000089108
fibronectin type III domain containing 3Ba
chr23_+_4741543 1.17 ENSDART00000144761
Raf-1 proto-oncogene, serine/threonine kinase a
chr2_-_30659222 1.15 ENSDART00000145405
catenin (cadherin-associated protein), delta 2b
chr25_+_30074947 1.13 ENSDART00000154849
si:ch211-147k10.5
chr8_+_10823069 1.11 ENSDART00000081341
mitogen-activated protein kinase 13
chr24_-_21903588 1.10 ENSDART00000180991
spermatogenesis associated 13
chr5_+_27525477 1.08 ENSDART00000051491
secreted frizzled-related protein 1a
chr23_-_26784736 1.06 ENSDART00000024064
ENSDART00000131615
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
chr24_-_21903360 1.04 ENSDART00000091252
spermatogenesis associated 13
chr20_+_22220988 1.04 ENSDART00000049204
kinase insert domain receptor (a type III receptor tyrosine kinase)
chr17_-_2690083 1.00 ENSDART00000135374
protein tyrosine phosphatase, non-receptor type 21
chr19_+_7636941 0.98 ENSDART00000081611
ENSDART00000163805
ENSDART00000112404
cingulin b
chr7_-_52498175 0.97 ENSDART00000129769
cingulin-like 1
chr25_-_16666886 0.96 ENSDART00000155764
solute carrier family 25 (glutamate carrier), member 18
chr2_-_10564019 0.96 ENSDART00000132167
coiled-coil domain containing 18
chr12_+_28854963 0.94 ENSDART00000153227
nuclear factor, erythroid 2-like 1b
chr22_-_23545307 0.92 ENSDART00000166915
crumbs family member 1, photoreceptor morphogenesis associated
chr16_+_34111919 0.92 ENSDART00000134037
ENSDART00000006061
ENSDART00000140552
transcription elongation factor A (SII), 3
chr24_+_25913162 0.91 ENSDART00000143099
ENSDART00000184814
mitogen-activated protein kinase kinase kinase 15
chr23_-_43713757 0.90 ENSDART00000192175
ATP-binding cassette, sub-family E (OABP), member 1
chr2_-_10563576 0.89 ENSDART00000185818
ENSDART00000190887
coiled-coil domain containing 18
chr21_-_11646878 0.89 ENSDART00000162426
ENSDART00000135937
ENSDART00000131448
ENSDART00000148097
ENSDART00000133443
calpastatin
chr17_+_34186632 0.88 ENSDART00000014306
membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5)
chr7_+_52712807 0.87 ENSDART00000174095
ENSDART00000174377
ENSDART00000174061
ENSDART00000174094
ENSDART00000110906
ENSDART00000174071
ENSDART00000174238
zinc finger protein 280D
chr22_-_10891213 0.85 ENSDART00000145229
rho/rac guanine nucleotide exchange factor (GEF) 18b
chr9_-_34300707 0.85 ENSDART00000049805
immunoglobulin-like domain containing receptor 2
chr3_-_12930217 0.83 ENSDART00000166322
platelet-derived growth factor alpha polypeptide b
chr11_+_39928828 0.83 ENSDART00000137516
ENSDART00000134082
vesicle-associated membrane protein 3 (cellubrevin)
chr4_-_21466480 0.82 ENSDART00000139962
PRKC, apoptosis, WT1, regulator
chr3_+_37574885 0.82 ENSDART00000055225
wingless-type MMTV integration site family, member 9B
chr9_-_28939181 0.82 ENSDART00000101276
ENSDART00000135334
erythrocyte membrane protein band 4.1 like 5
chr21_-_30994577 0.78 ENSDART00000065503
post-GPI attachment to proteins 2
chr18_-_6766354 0.78 ENSDART00000132611
adrenomedullin 2b
chr15_-_41245962 0.77 ENSDART00000155359
single-pass membrane protein with coiled-coil domains 4
chr16_+_21918503 0.75 ENSDART00000167919
zinc finger protein 687a
chr17_-_12758171 0.74 ENSDART00000131564
breast cancer metastasis-suppressor 1-like a
chr14_+_35424539 0.74 ENSDART00000171809
ENSDART00000162185
synaptotagmin-like 4
chr21_-_9562272 0.73 ENSDART00000162225
ENSDART00000163874
ENSDART00000168173
protein tyrosine phosphatase, non-receptor type 13
chr13_+_25486608 0.72 ENSDART00000057689
BCL2 associated athanogene 3
chr4_-_78026285 0.72 ENSDART00000168273
chaperonin containing TCP1 subunit 2
chr6_-_22145926 0.71 ENSDART00000038818
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr4_+_8532580 0.70 ENSDART00000162065
wingless-type MMTV integration site family, member 5b
chr4_+_16710001 0.69 ENSDART00000035899
plakophilin 2
chr3_-_50046004 0.68 ENSDART00000109544
si:ch1073-100f3.2
chr5_+_37649206 0.65 ENSDART00000149151
ENSDART00000097723
spectrin, beta, non-erythrocytic 2
chr8_+_26034623 0.64 ENSDART00000004521
ENSDART00000142555
ariadne homolog 2 (Drosophila)
chr4_+_18489207 0.64 ENSDART00000135276
si:dkey-202b22.5
chr16_+_14684916 0.63 ENSDART00000138611
collagen, type XIV, alpha 1a
chr12_+_20149707 0.62 ENSDART00000181942
forkhead box J1b
chr14_-_22152064 0.62 ENSDART00000115422
NudC domain containing 2
chr19_-_10612774 0.61 ENSDART00000091898
si:dkey-211g8.6
chr23_-_15090782 0.61 ENSDART00000133624
si:ch211-218g4.2
chr24_-_34335265 0.60 ENSDART00000128690
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr7_+_38898208 0.60 ENSDART00000172251
cAMP responsive element binding protein 3-like 1
chr11_-_42417194 0.57 ENSDART00000191086
ENSDART00000076650
ENSDART00000165903
ENSDART00000104444
sarcolemma associated protein a
chr19_+_41520892 0.56 ENSDART00000182218
ENSDART00000115123
CREB regulated transcription coactivator 2
chr1_+_7679328 0.56 ENSDART00000163488
ENSDART00000190070
engrailed homeobox 1b
chr17_-_30521043 0.55 ENSDART00000087111
intersectin 2b
chr3_+_16265924 0.54 ENSDART00000122519
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr18_+_41313999 0.54 ENSDART00000048985
ventricular zone expressed PH domain-containing 1
chr10_-_1827225 0.54 ENSDART00000058627
erythrocyte membrane protein band 4.1 like 4A
chr2_-_32247341 0.52 ENSDART00000146452
family with sequence similarity 49, member Ba
chr1_-_21204114 0.52 ENSDART00000141077
si:dkey-253i9.4
chr23_+_36083529 0.52 ENSDART00000053295
ENSDART00000130260
homeobox C10a
chr2_-_6115389 0.51 ENSDART00000134921
peroxiredoxin 1
chr6_+_27361978 0.51 ENSDART00000065238
ciliary rootlet coiled-coil, rootletin family member 2
chr7_-_71456117 0.50 ENSDART00000042492
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
chr19_+_7759354 0.49 ENSDART00000151400
ubiquitin associated protein 2-like
chr21_+_3778498 0.49 ENSDART00000139813
torsin family 1
chr21_+_29227224 0.48 ENSDART00000013641
adrenoceptor alpha 1Ba
chr6_+_46309795 0.48 ENSDART00000154817
si:dkeyp-67f1.1
chr11_+_355305 0.48 ENSDART00000147426
p53 and DNA-damage regulated 1
chr7_+_4524059 0.47 ENSDART00000187693
si:dkey-83f18.4
chr8_-_53926228 0.47 ENSDART00000015554
UbiA prenyltransferase domain containing 1
chr16_-_39570832 0.46 ENSDART00000039832
transforming growth factor beta receptor 2b
chr21_+_44581654 0.46 ENSDART00000187201
ENSDART00000180360
ENSDART00000191543
ENSDART00000180039
ENSDART00000186308
transmembrane protein 164
chr22_+_26600834 0.46 ENSDART00000157411
adenylate cyclase 9
chr7_+_31051603 0.43 ENSDART00000108721
tight junction protein 1a
chr2_+_1988036 0.43 ENSDART00000155956
synovial sarcoma, X breakpoint 2 interacting protein a
chr15_+_24746444 0.42 ENSDART00000032306
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1
chr14_+_29941266 0.41 ENSDART00000112757
family with sequence similarity 149 member A
chr13_-_39159810 0.41 ENSDART00000131508
collagen, type IX, alpha 1b
chr7_+_38897836 0.40 ENSDART00000024330
cAMP responsive element binding protein 3-like 1
chr15_+_20529197 0.40 ENSDART00000060935
ENSDART00000137926
ENSDART00000140087
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr16_+_11029762 0.39 ENSDART00000091183
Ets2 repressor factor like 3
chr19_+_10558994 0.39 ENSDART00000148353
upstream transcription factor 2, c-fos interacting
chr24_+_22022109 0.38 ENSDART00000133686
rhophilin associated tail protein 1-like
chr13_+_24584401 0.38 ENSDART00000057599
fucose mutarotase
chr9_+_17787864 0.37 ENSDART00000013111
diacylglycerol kinase, eta
chr7_-_29292206 0.36 ENSDART00000086753
death-associated protein kinase 2a
chr14_-_46897067 0.35 ENSDART00000058789
quinoid dihydropteridine reductase a
chr4_+_31085014 0.35 ENSDART00000172541
si:dkey-47k16.4
chr3_+_53240562 0.33 ENSDART00000031234
syntaxin binding protein 2
chr12_+_20149305 0.32 ENSDART00000126676
ENSDART00000153327
forkhead box J1b
chr18_+_38191346 0.32 ENSDART00000052703
nucleobindin 2b
chr7_-_41468751 0.31 ENSDART00000150146
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b
chr4_-_17803784 0.31 ENSDART00000187195
Spi-2 proto-oncogene
chr8_+_11425048 0.31 ENSDART00000018739
tight junction protein 2b (zona occludens 2)
chr15_+_3284684 0.31 ENSDART00000179778
forkhead box O1 a
chr20_-_52271015 0.30 ENSDART00000074307
rhophilin, Rho GTPase binding protein 1
chr2_+_9560740 0.30 ENSDART00000003465
GIPC PDZ domain containing family, member 2
chr5_+_44806374 0.30 ENSDART00000184237
cathepsin La
chr20_-_52271262 0.28 ENSDART00000135463
rhophilin, Rho GTPase binding protein 1
chr5_-_65782783 0.28 ENSDART00000130888
ENSDART00000050855
notch 1b
chr12_-_20409794 0.27 ENSDART00000077936
leucine carboxyl methyltransferase 1
chr3_-_56030117 0.26 ENSDART00000113030
ENSDART00000157764
centrosomal protein 112
chr7_-_18700364 0.26 ENSDART00000112359
si:ch211-119e14.9
chr13_-_4333181 0.26 ENSDART00000122406
zinc finger protein 318
chr21_-_18086114 0.25 ENSDART00000143987
vav 2 guanine nucleotide exchange factor
chr7_-_26497947 0.24 ENSDART00000058910
SRY (sex determining region Y)-box 19b
chr21_+_22237964 0.24 ENSDART00000003181
myosin VIIAb
chr9_+_44034990 0.22 ENSDART00000162406
integrin alpha 4
chr22_-_6362442 0.22 ENSDART00000149907
ENSDART00000106104
zgc:113298
chr7_+_24889783 0.20 ENSDART00000005329
ENSDART00000159955
MAP/microtubule affinity-regulating kinase 2b
chr21_+_32338897 0.19 ENSDART00000110137
si:ch211-247j9.1
chr9_+_44034790 0.17 ENSDART00000166110
ENSDART00000176954
integrin alpha 4
chr23_-_6522099 0.17 ENSDART00000092214
ENSDART00000183380
ENSDART00000138020
bone morphogenetic protein 7b
chr23_-_31400792 0.17 ENSDART00000132736
Leber congenital amaurosis 5
chr19_-_45650994 0.16 ENSDART00000163504
trichorhinophalangeal syndrome I
chr17_-_49443247 0.16 ENSDART00000059245
glycoprotein hormones, alpha polypeptide
chr9_+_48415043 0.16 ENSDART00000159930
low density lipoprotein receptor-related protein 2a
chr18_+_9493720 0.15 ENSDART00000053125
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr9_+_32358514 0.15 ENSDART00000144608
phospholipase C like 1
chr11_+_27969045 0.14 ENSDART00000146461
alkaline phosphatase, liver/bone/kidney
chr17_-_49443399 0.14 ENSDART00000155293
glycoprotein hormones, alpha polypeptide
chr2_-_6115688 0.14 ENSDART00000081663
peroxiredoxin 1
chr4_+_2228754 0.12 ENSDART00000166058
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr3_-_61494840 0.11 ENSDART00000101957
BAI1-associated protein 2-like 1b
chr23_+_37579107 0.11 ENSDART00000169376
pleckstrin homology domain containing, family G (with RhoGef domain) member 5b
chr13_-_42560662 0.10 ENSDART00000124898

chr7_+_49664174 0.10 ENSDART00000137059
ENSDART00000131210
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr24_+_22731228 0.10 ENSDART00000146733
si:dkey-225k4.1
chr2_+_2470687 0.09 ENSDART00000184024
ENSDART00000061955
myosin, light chain 13
chr17_+_26543690 0.09 ENSDART00000156417
SPARC-like 2
chr8_-_24970790 0.09 ENSDART00000141267
si:ch211-199o1.2
chr15_+_25489406 0.08 ENSDART00000162482
zgc:152863
chr16_-_33930759 0.08 ENSDART00000177453
dynein, axonemal, light intermediate chain 1
chr20_+_21583639 0.05 ENSDART00000131069
estrogen receptor 2a
chr7_+_4625915 0.04 ENSDART00000108557
si:ch211-225k7.3
chr24_+_26742226 0.03 ENSDART00000079721
growth hormone secretagogue receptor b
chr11_+_21587950 0.02 ENSDART00000162251
zgc:101564
chr5_-_9216758 0.02 ENSDART00000134896
ENSDART00000147000
low-density lipoprotein receptor related-protein 13
chr20_+_45853154 0.00 ENSDART00000181109

Network of associatons between targets according to the STRING database.

First level regulatory network of scrt1a+scrt1b+scrt2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.4 2.2 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.3 1.4 GO:0048103 neuronal stem cell division(GO:0036445) somatic stem cell division(GO:0048103)
0.3 2.6 GO:0048240 sperm capacitation(GO:0048240)
0.3 1.5 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.3 1.3 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.2 0.7 GO:0010664 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.2 2.1 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.2 0.9 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.2 0.8 GO:0021744 medulla oblongata development(GO:0021550) dorsal motor nucleus of vagus nerve development(GO:0021744)
0.2 2.0 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.2 0.5 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.2 0.5 GO:0042373 vitamin K metabolic process(GO:0042373) cellular response to fluid shear stress(GO:0071498)
0.2 2.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 1.4 GO:0033700 phospholipid efflux(GO:0033700)
0.1 0.7 GO:1904105 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591) positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.1 2.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.7 GO:0071422 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.1 0.9 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 1.4 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 1.1 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.3 GO:0010893 positive regulation of steroid biosynthetic process(GO:0010893) positive regulation of steroid metabolic process(GO:0045940)
0.1 0.7 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 0.5 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 1.0 GO:0015800 C4-dicarboxylate transport(GO:0015740) acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.1 0.8 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 0.6 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 1.8 GO:0021984 adenohypophysis development(GO:0021984)
0.1 0.5 GO:0003321 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.1 0.5 GO:0021628 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.1 0.6 GO:0000303 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 0.4 GO:0006004 fucose metabolic process(GO:0006004)
0.1 0.8 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.3 GO:0048745 smooth muscle tissue development(GO:0048745)
0.1 0.4 GO:0042438 melanin biosynthetic process(GO:0042438)
0.0 0.9 GO:0033750 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753) rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0 0.6 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.8 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 2.1 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 1.2 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.4 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 1.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.3 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.3 GO:0032094 response to food(GO:0032094)
0.0 1.1 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.3 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 1.1 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.2 GO:1900028 negative regulation of Rac protein signal transduction(GO:0035021) wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.0 0.4 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 2.3 GO:0001945 lymph vessel development(GO:0001945)
0.0 1.0 GO:0035924 cellular response to vascular endothelial growth factor stimulus(GO:0035924)
0.0 0.8 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 1.4 GO:0021515 cell differentiation in spinal cord(GO:0021515)
0.0 0.3 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.0 0.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 1.0 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.6 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.9 GO:0034599 cellular response to oxidative stress(GO:0034599)
0.0 1.0 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 0.2 GO:0070293 renal absorption(GO:0070293)
0.0 0.2 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.0 1.2 GO:0006979 response to oxidative stress(GO:0006979)
0.0 0.9 GO:0003146 heart jogging(GO:0003146)
0.0 0.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 1.3 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.0 0.9 GO:0006414 translational elongation(GO:0006414)
0.0 0.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.8 GO:0007492 endoderm development(GO:0007492)
0.0 0.6 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.7 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.1 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.8 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.6 GO:0051693 actin filament capping(GO:0051693)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0008091 spectrin(GO:0008091)
0.1 1.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 2.0 GO:0031430 M band(GO:0031430)
0.1 2.2 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.5 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.7 GO:0014704 intercalated disc(GO:0014704)
0.1 0.5 GO:0016272 prefoldin complex(GO:0016272)
0.1 2.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.9 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.7 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.9 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 2.2 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 2.8 GO:0005912 adherens junction(GO:0005912)
0.0 0.7 GO:0030018 Z disc(GO:0030018)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.3 1.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.3 2.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.7 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.1 0.9 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.4 GO:0042806 fucose binding(GO:0042806)
0.1 0.7 GO:0019215 intermediate filament binding(GO:0019215)
0.1 1.4 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.6 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.8 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.4 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.1 2.0 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 1.0 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 1.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.5 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.9 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.5 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.5 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.5 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 1.5 GO:0005112 Notch binding(GO:0005112)
0.1 0.7 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 1.0 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.4 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 2.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.1 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 1.3 GO:0005109 frizzled binding(GO:0005109)
0.0 1.1 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.3 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.5 GO:0019894 kinesin binding(GO:0019894)
0.0 1.2 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.7 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.5 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.7 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.1 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.2 GO:0045296 cadherin binding(GO:0045296)
0.0 0.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.5 GO:0000049 tRNA binding(GO:0000049)
0.0 3.7 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 1.0 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 1.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 2.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.8 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.4 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.6 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 1.0 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 2.2 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.5 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.7 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 1.1 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation