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PRJEB1986: zebrafish developmental stages transcriptome

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Results for rorc

Z-value: 0.93

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Transcription factors associated with rorc

Gene Symbol Gene ID Gene Info
rorc
ENSDARG00000087195 RAR-related orphan receptor C

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rorcdr11_v1_chr16_+_17913936_17913945-0.351.4e-01Click!

Activity profile of rorc motif

Sorted Z-values of rorc motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_43314700 5.17 ENSDART00000049045
ENSDART00000133158
matn1
matrilin 1
chr14_+_17376940 2.90 ENSDART00000054590
ENSDART00000010148
spon2b
spondin 2b, extracellular matrix protein
chr15_+_19682013 2.62 ENSDART00000127368
si:dkey-4p15.5
si:dkey-4p15.5
chr6_+_13742899 2.43 ENSDART00000104722
cdk5r2a
cyclin-dependent kinase 5, regulatory subunit 2a (p39)
chr15_+_19681718 1.85 ENSDART00000164803
si:dkey-4p15.5
si:dkey-4p15.5
chr20_+_16750177 1.66 ENSDART00000185357
calm1b
calmodulin 1b
chr15_-_37829160 1.64 ENSDART00000099425
ctrl
chymotrypsin-like
chr5_+_2815021 1.63 ENSDART00000020472
hpda
4-hydroxyphenylpyruvate dioxygenase a
chr19_+_4990320 1.59 ENSDART00000147056
zgc:91968
zgc:91968
chr21_+_27189490 1.58 ENSDART00000125349
bada
BCL2 associated agonist of cell death a
chr19_+_4990496 1.53 ENSDART00000151050
ENSDART00000017535
zgc:91968
zgc:91968
chr8_+_25351863 1.52 ENSDART00000034092
dnase1l1l
deoxyribonuclease I-like 1-like
chr10_-_39321367 1.40 ENSDART00000129647
smtlb
somatolactin beta
chr23_+_19564392 1.33 ENSDART00000144746
atp6ap1lb
ATPase H+ transporting accessory protein 1 like b
chr5_-_11573490 1.23 ENSDART00000109577
FO704871.1

chr21_+_40106448 1.22 ENSDART00000100166
serpinf1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr17_-_6738538 1.14 ENSDART00000157125
vsnl1b
visinin-like 1b
chr13_+_29470442 1.13 ENSDART00000028417
lrit2
leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
chr4_+_17280868 1.11 ENSDART00000145349
bcat1
branched chain amino-acid transaminase 1, cytosolic
chr20_-_14680897 1.03 ENSDART00000063857
ENSDART00000161314
scrn2
secernin 2
chr24_-_32408404 1.03 ENSDART00000144157
si:ch211-56a11.2
si:ch211-56a11.2
chr11_-_24458786 1.01 ENSDART00000089713
mxra8a
matrix-remodelling associated 8a
chr11_+_30672282 1.01 ENSDART00000023981
ENSDART00000188846
ttbk1a
tau tubulin kinase 1a
chr7_+_65240227 0.96 ENSDART00000168287
bco1l
beta-carotene oxygenase 1, like
chr23_-_36724575 0.92 ENSDART00000159560
agap2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr19_+_30990129 0.90 ENSDART00000052169
ENSDART00000193376
sync
syncoilin, intermediate filament protein
chr19_+_30990815 0.87 ENSDART00000134645
sync
syncoilin, intermediate filament protein
chr22_-_13544244 0.86 ENSDART00000110136
cntnap5b
contactin associated protein-like 5b
chr3_+_1016404 0.81 ENSDART00000189545
si:ch1073-464p5.5
si:ch1073-464p5.5
chr22_-_38480186 0.79 ENSDART00000171704
soul4
heme-binding protein soul4
chr8_-_29706882 0.79 ENSDART00000045909
prf1.5
perforin 1.5
chr21_+_30549512 0.78 ENSDART00000132831
rab38c
RAB38c, member of RAS oncogene family
chr5_-_16983336 0.78 ENSDART00000038740
galnt9
polypeptide N-acetylgalactosaminyltransferase 9
chr4_-_4129187 0.78 ENSDART00000146889
asb15b
ankyrin repeat and SOCS box containing 15b
chr2_+_28889936 0.73 ENSDART00000078232
cdh10a
cadherin 10, type 2a (T2-cadherin)
chr9_+_35876927 0.72 ENSDART00000138834
mab21l3
mab-21-like 3
chr2_+_49417900 0.71 ENSDART00000122742
ENSDART00000160783
rorcb
RAR-related orphan receptor C b
chr12_+_1286642 0.68 ENSDART00000157467
pemt
phosphatidylethanolamine N-methyltransferase
chr24_+_24809877 0.68 ENSDART00000185117
dnajc5b
DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chr22_-_600016 0.63 ENSDART00000086434
tmcc2
transmembrane and coiled-coil domain family 2
chr15_-_12360409 0.63 ENSDART00000164596
tmprss13a
transmembrane protease, serine 13a
chr5_-_30079434 0.62 ENSDART00000133981
bco2a
beta-carotene oxygenase 2a
chr18_+_7594012 0.60 ENSDART00000062150
zgc:77752
zgc:77752
chr22_-_11124419 0.59 ENSDART00000149634
atp6ap2
ATPase H+ transporting accessory protein 2
chr23_+_44741500 0.58 ENSDART00000166421
atp1b2a
ATPase Na+/K+ transporting subunit beta 2a
chr15_-_24178893 0.56 ENSDART00000077980
pipox
pipecolic acid oxidase
chr1_+_9708801 0.55 ENSDART00000189621
elfn1b
extracellular leucine-rich repeat and fibronectin type III domain containing 1b
chr2_-_56655769 0.53 ENSDART00000113589
gpx4b
glutathione peroxidase 4b
chr16_+_26738404 0.53 ENSDART00000163110
fsbp
fibrinogen silencer binding protein
chr13_+_21768447 0.52 ENSDART00000100941
chchd1
coiled-coil-helix-coiled-coil-helix domain containing 1
chr25_-_32888115 0.52 ENSDART00000087586
c2cd4a
C2 calcium dependent domain containing 4A
chr19_-_8096984 0.51 ENSDART00000146987
si:dkey-266f7.9
si:dkey-266f7.9
chr18_+_22302635 0.51 ENSDART00000141051
carmil2
capping protein regulator and myosin 1 linker 2
chr12_+_16106459 0.50 ENSDART00000114174
muc13b
mucin 13b, cell surface associated
chr25_-_17918810 0.50 ENSDART00000023959
arntl1a
aryl hydrocarbon receptor nuclear translocator-like 1a
chr10_+_2232023 0.49 ENSDART00000097695
cntnap3
contactin associated protein like 3
chr11_+_28476298 0.49 ENSDART00000122319
lrrc38b
leucine rich repeat containing 38b
chr21_-_40557281 0.47 ENSDART00000172327
taok1b
TAO kinase 1b
chr7_+_66048102 0.47 ENSDART00000104523
arntl1b
aryl hydrocarbon receptor nuclear translocator-like 1b
chr3_-_22829710 0.45 ENSDART00000055659
cyb561
cytochrome b561
chr18_-_42313798 0.45 ENSDART00000098639
cntn5
contactin 5
chr21_-_5881344 0.44 ENSDART00000009241
rpl35
ribosomal protein L35
chr17_-_2126517 0.44 ENSDART00000013093
zfyve19
zinc finger, FYVE domain containing 19
chr3_-_26191960 0.44 ENSDART00000113843
ypel3
yippee-like 3
chr7_-_28058442 0.43 ENSDART00000173842
si:ch211-235p24.2
si:ch211-235p24.2
chr7_+_24573721 0.42 ENSDART00000173938
ENSDART00000173681
si:dkeyp-75h12.7
si:dkeyp-75h12.7
chr15_+_42599501 0.42 ENSDART00000177646
grik1b
glutamate receptor, ionotropic, kainate 1b
chr9_+_21993092 0.41 ENSDART00000059693
crygm7
crystallin, gamma M7
chr8_+_25352268 0.41 ENSDART00000187829
dnase1l1l
deoxyribonuclease I-like 1-like
chr15_-_31419805 0.41 ENSDART00000060111
or111-11
odorant receptor, family D, subfamily 111, member 11
chr24_-_31422574 0.39 ENSDART00000158567
cngb3.1
cyclic nucleotide gated channel beta 3, tandem duplicate 1
chr19_-_8604429 0.38 ENSDART00000151165
trim46b
tripartite motif containing 46b
chr16_+_30438041 0.38 ENSDART00000137977
pear1
platelet endothelial aggregation receptor 1
chr11_-_29737088 0.37 ENSDART00000159828
si:ch211-218g23.6
si:ch211-218g23.6
chr24_-_35707552 0.36 ENSDART00000165199
mapre2
microtubule-associated protein, RP/EB family, member 2
chr2_-_56649883 0.35 ENSDART00000191786
gpx4b
glutathione peroxidase 4b
chr16_-_24561354 0.35 ENSDART00000193278
ENSDART00000126274
si:ch211-79k12.2
si:ch211-79k12.2
chr17_-_13072334 0.34 ENSDART00000159598
CU469462.1

chr25_-_17918536 0.34 ENSDART00000148660
arntl1a
aryl hydrocarbon receptor nuclear translocator-like 1a
chr21_+_41649336 0.32 ENSDART00000164694
ENSDART00000181539
ppp2r2bb
protein phosphatase 2, regulatory subunit B, beta b
chr12_-_32013125 0.32 ENSDART00000153355
grin2cb
glutamate receptor, ionotropic, N-methyl D-aspartate 2Cb
chr9_-_48937089 0.32 ENSDART00000193442
cers6
ceramide synthase 6
chr2_+_48282590 0.29 ENSDART00000035338
lpar5a
lysophosphatidic acid receptor 5a
chr3_-_5362347 0.29 ENSDART00000187511
trim35-7
tripartite motif containing 35-7
chr22_-_5752009 0.28 ENSDART00000190052
bcdin3d
BCDIN3 domain containing
chr9_+_13682133 0.27 ENSDART00000175639
mpp4a
membrane protein, palmitoylated 4a (MAGUK p55 subfamily member 4)
chr22_+_8612462 0.27 ENSDART00000114586
CR450686.1

chr1_-_33353778 0.26 ENSDART00000041191
gyg2
glycogenin 2
chr6_-_39605734 0.25 ENSDART00000044276
ENSDART00000179059
dip2bb
disco-interacting protein 2 homolog Bb
chr3_-_31226841 0.25 ENSDART00000085903
syt17
synaptotagmin XVII
chr19_+_2590182 0.25 ENSDART00000162293
si:ch73-345f18.3
si:ch73-345f18.3
chr17_-_37312922 0.24 ENSDART00000153555
si:ch211-180n24.3
si:ch211-180n24.3
chr11_-_1948784 0.24 ENSDART00000082475
nr1d4b
nuclear receptor subfamily 1, group D, member 4b
chr8_-_51349429 0.23 ENSDART00000134043
ENSDART00000098282
si:ch211-198o12.4
si:ch211-198o12.4
chr3_-_39198113 0.23 ENSDART00000102690
RETSAT
zgc:154169
chr17_-_27976031 0.22 ENSDART00000154829
ptafr
platelet-activating factor receptor
chr17_-_12718547 0.22 ENSDART00000193002
BX294375.1

chr7_-_22632518 0.21 ENSDART00000161046
si:dkey-112a7.4
si:dkey-112a7.4
chr21_-_25613249 0.21 ENSDART00000137896
fibpb
fibroblast growth factor (acidic) intracellular binding protein b
chr22_+_26263290 0.21 ENSDART00000184840
BX649315.1

chr8_+_21146262 0.20 ENSDART00000045684
porcn
porcupine O-acyltransferase
chr6_-_8244474 0.20 ENSDART00000151358
rgl3a
ral guanine nucleotide dissociation stimulator-like 3a
chr25_-_19374710 0.20 ENSDART00000184483
ENSDART00000188706
map1ab
microtubule-associated protein 1Ab
chr23_-_5683147 0.19 ENSDART00000102766
ENSDART00000067351
tnnt2a
troponin T type 2a (cardiac)
chr22_+_36704764 0.18 ENSDART00000146662
trim35-33
tripartite motif containing 35-33
chr5_-_31689796 0.18 ENSDART00000184319
ENSDART00000190229
ENSDART00000186294
ENSDART00000170313
ENSDART00000147065
ENSDART00000134427
ENSDART00000098172
sh3glb2b
SH3-domain GRB2-like endophilin B2b
chr19_+_41173386 0.18 ENSDART00000142773
asb4
ankyrin repeat and SOCS box containing 4
chr6_-_43005901 0.18 ENSDART00000161071
si:ch73-361p23.3
si:ch73-361p23.3
chr24_-_982443 0.15 ENSDART00000063151
napga
N-ethylmaleimide-sensitive factor attachment protein, gamma a
chr8_+_18464235 0.14 ENSDART00000110571
alkal1
ALK and LTK ligand 1
chr25_+_30233638 0.14 ENSDART00000192558
ENSDART00000067057
ENSDART00000147327
ENSDART00000145924
ENSDART00000148250
alkbh3
alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase
chr20_-_4738101 0.14 ENSDART00000050201
ENSDART00000152559
ENSDART00000053858
ENSDART00000125620
papola
poly(A) polymerase alpha
chr5_-_39698224 0.13 ENSDART00000076929
prkg2
protein kinase, cGMP-dependent, type II
chr25_+_3035384 0.13 ENSDART00000184219
ENSDART00000149360
mpi
mannose phosphate isomerase
chr2_-_25120197 0.13 ENSDART00000132549
pccb
propionyl CoA carboxylase, beta polypeptide
chr7_-_22632938 0.13 ENSDART00000159867
ENSDART00000165706
si:dkey-112a7.4
si:dkey-112a7.4
chr2_-_8648440 0.13 ENSDART00000135743
si:ch211-71m22.3
si:ch211-71m22.3
chr11_+_26363435 0.12 ENSDART00000088800
ppcs
phosphopantothenoylcysteine synthetase
chr21_-_20725853 0.12 ENSDART00000114502
si:ch211-22d5.2
si:ch211-22d5.2
chr17_+_2214283 0.12 ENSDART00000189187
pak6a
p21 protein (Cdc42/Rac)-activated kinase 6a
chr20_+_44082532 0.12 ENSDART00000188481
BX510352.1

chr1_+_19433004 0.11 ENSDART00000133959
clockb
clock circadian regulator b
chr15_-_34322915 0.11 ENSDART00000190543
ENSDART00000019651
ENSDART00000193601
dgkb
diacylglycerol kinase, beta
chr11_+_19159083 0.11 ENSDART00000138964
adamts9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr20_-_30377221 0.11 ENSDART00000126229
rps7
ribosomal protein S7
chr15_-_34878388 0.11 ENSDART00000154094
mgat1a
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase a
chr5_+_70155935 0.11 ENSDART00000165570
rgs3a
regulator of G protein signaling 3a
chr8_+_18463797 0.10 ENSDART00000148958
alkal1
ALK and LTK ligand 1
chr12_+_31616412 0.10 ENSDART00000124439
cpn1
carboxypeptidase N, polypeptide 1
chr15_-_2841677 0.08 ENSDART00000026145
ENSDART00000180290
AMOTL1
angiomotin like 1
chr3_-_5555500 0.08 ENSDART00000176133
ENSDART00000057464
trim35-31
tripartite motif containing 35-31
chr6_-_49159207 0.07 ENSDART00000041942
tspan2a
tetraspanin 2a
chr3_+_32698424 0.07 ENSDART00000055340
fus
FUS RNA binding protein
chr25_-_1235457 0.07 ENSDART00000093093
coro2bb
coronin, actin binding protein, 2Bb
chr25_-_19219807 0.06 ENSDART00000183577
acanb
aggrecan b
chr17_-_36513936 0.05 ENSDART00000165075
DCDC2C
si:dkey-25g12.4
chr10_+_40548616 0.04 ENSDART00000147894
si:ch211-238p8.10
si:ch211-238p8.10
chr23_-_36316352 0.04 ENSDART00000014840
nfe2
nuclear factor, erythroid 2
chr3_+_13637383 0.04 ENSDART00000166000
si:ch211-194b1.1
si:ch211-194b1.1
chr16_+_17715243 0.03 ENSDART00000149437
ENSDART00000149596
si:dkey-87o1.2
si:dkey-87o1.2
chr6_+_32415132 0.03 ENSDART00000155790
kank4
KN motif and ankyrin repeat domains 4
chr8_+_42917515 0.03 ENSDART00000021715
slc23a2
solute carrier family 23 (ascorbic acid transporter), member 2
chr7_+_48675347 0.03 ENSDART00000157917
ENSDART00000185580
trpm5
transient receptor potential cation channel, subfamily M, member 5
chr21_+_19517492 0.03 ENSDART00000123168
ENSDART00000187993
gzmk
granzyme K
chr21_+_21812311 0.02 ENSDART00000151253
neu3.4
sialidase 3 (membrane sialidase), tandem duplicate 4
chr5_+_52167986 0.02 ENSDART00000162256
ENSDART00000073626
slc14a2
solute carrier family 14 (urea transporter), member 2
chr8_+_26254903 0.01 ENSDART00000113763
slc26a6
solute carrier family 26, member 6

Network of associatons between targets according to the STRING database.

First level regulatory network of rorc

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0009098 leucine biosynthetic process(GO:0009098)
0.3 1.6 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 3.1 GO:0090382 phagosome maturation(GO:0090382)
0.2 1.6 GO:0042214 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 0.4 GO:0009838 abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878)
0.1 0.6 GO:0006554 lysine catabolic process(GO:0006554) L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.1 1.4 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.1 1.9 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.1 0.7 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 0.3 GO:0070920 regulation of production of small RNA involved in gene silencing by RNA(GO:0070920) regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798)
0.1 0.2 GO:0061355 Wnt protein secretion(GO:0061355)
0.1 2.4 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.1 0.5 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.2 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.0 0.1 GO:0042546 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.0 0.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.2 GO:0070375 ERK5 cascade(GO:0070375) regulation of ERK5 cascade(GO:0070376) positive regulation of ERK5 cascade(GO:0070378)
0.0 0.4 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.4 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.8 GO:0032438 melanosome organization(GO:0032438)
0.0 0.6 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.6 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.8 GO:0019835 cytolysis(GO:0019835)
0.0 0.6 GO:1990798 pancreas regeneration(GO:1990798)
0.0 1.0 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.0 0.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.8 GO:0009648 photoperiodism(GO:0009648)
0.0 0.1 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.0 0.6 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 1.3 GO:0030641 regulation of cellular pH(GO:0030641)
0.0 0.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 4.8 GO:0051216 cartilage development(GO:0051216)
0.0 0.5 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 0.3 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 1.2 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.5 GO:0032543 mitochondrial translation(GO:0032543)
0.0 1.0 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.4 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.3 3.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2 1.3 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 1.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0 0.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.8 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.1 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.7 GO:0016342 catenin complex(GO:0016342)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.5 1.4 GO:0005131 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
0.3 1.1 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 1.0 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.2 1.9 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.2 2.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2 0.9 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.2 1.6 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 0.4 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.4 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 1.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.6 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1 9.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.3 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.2 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.4 GO:0005222 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.2 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 0.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 3.6 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.4 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.0 1.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0008171 O-methyltransferase activity(GO:0008171)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 5.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.9 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.1 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism