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PRJEB1986: zebrafish developmental stages transcriptome

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Results for rfx7a+rfx7b

Z-value: 0.88

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Transcription factors associated with rfx7a+rfx7b

Gene Symbol Gene ID Gene Info
ENSDARG00000077237 regulatory factor X7a
ENSDARG00000103691 regulatory factor X7b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rfx7adr11_v1_chr7_+_34506937_34506937-0.633.8e-03Click!
rfx7bdr11_v1_chr25_+_388258_388258-0.077.9e-01Click!

Activity profile of rfx7a+rfx7b motif

Sorted Z-values of rfx7a+rfx7b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr22_+_438714 3.24 ENSDART00000136491
cadherin, EGF LAG seven-pass G-type receptor 2
chr2_-_42960353 3.01 ENSDART00000098303
otoconin 90
chr4_-_78026285 2.87 ENSDART00000168273
chaperonin containing TCP1 subunit 2
chr10_-_22797959 2.56 ENSDART00000183269
procollagen C-endopeptidase enhancer a
chr1_+_604127 2.43 ENSDART00000133165
junctional adhesion molecule 2a
chr4_+_34343524 2.19 ENSDART00000171694
si:ch211-246b8.5
chr6_-_55297274 2.11 ENSDART00000184283
ubiquitin-conjugating enzyme E2C
chr18_+_5618368 2.03 ENSDART00000159945
unc-51 like kinase 3
chr17_-_28811747 1.80 ENSDART00000001444
G2/M-phase specific E3 ubiquitin protein ligase
chr11_-_40519886 1.76 ENSDART00000172819
migration and invasion inhibitory protein
chr10_-_10863936 1.73 ENSDART00000180568
NOTCH regulated ankyrin repeat protein a
chr14_-_12051610 1.64 ENSDART00000193741
ENSDART00000029366
zgc:66447
chr1_-_51710225 1.63 ENSDART00000057601
ENSDART00000152745
small nuclear ribonucleoprotein polypeptide B2
chr14_-_38827442 1.59 ENSDART00000160000
spindle apparatus coiled-coil protein 1
chr21_-_29991098 1.54 ENSDART00000155772
si:ch73-190f9.4
chr10_-_10864331 1.54 ENSDART00000122657
NOTCH regulated ankyrin repeat protein a
chr21_-_23307653 1.53 ENSDART00000140284
ENSDART00000134103
zinc finger and BTB domain containing 16a
chr22_-_24984733 1.51 ENSDART00000142147
ENSDART00000187284
dynein, axonemal, light chain 4b
chr3_-_60175470 1.49 ENSDART00000156597
si:ch73-364h19.1
chr20_+_30797329 1.43 ENSDART00000145066
NHS-like 1b
chr7_+_22981909 1.41 ENSDART00000122449
cyclin B3
chr7_+_22982201 1.37 ENSDART00000134116
cyclin B3
chr18_-_14677936 1.33 ENSDART00000111995
si:dkey-238o13.4
chr21_-_29735366 1.33 ENSDART00000181668

chr8_+_2487250 1.26 ENSDART00000081325
dynein, light chain, LC8-type 1
chr12_-_48168135 1.26 ENSDART00000186624
phosphatase domain containing, paladin 1a
chr6_-_19683406 1.26 ENSDART00000158041
cilia and flagella associated protein 52
chr25_+_34845115 1.26 ENSDART00000061996
transmembrane protein 231
chr19_-_27588842 1.25 ENSDART00000121643
si:dkeyp-46h3.2
chr2_-_7246848 1.22 ENSDART00000146434
zgc:153115
chr21_-_29838117 1.21 ENSDART00000160727

chr14_-_38826739 1.20 ENSDART00000187633
spindle apparatus coiled-coil protein 1
chr12_+_17620067 1.18 ENSDART00000073599
radial spoke head 10 homolog B
chr11_+_6116503 1.17 ENSDART00000176170
nuclear receptor subfamily 2, group F, member 6b
chr10_+_44692272 1.15 ENSDART00000157458
ubiquitin C
chr21_-_29295713 1.15 ENSDART00000170081

chr1_-_59567685 1.14 ENSDART00000159144
ENSDART00000182913
zmp:0000001082
chr21_-_29990574 1.14 ENSDART00000185800
si:ch73-190f9.4
chr10_-_17231917 1.14 ENSDART00000038577
RAB36, member RAS oncogene family
chr15_+_37589698 1.13 ENSDART00000076066
ENSDART00000153894
ENSDART00000156298
lin-37 DREAM MuvB core complex component
chr11_+_6115621 1.12 ENSDART00000165031
ENSDART00000027666
ENSDART00000161458
nuclear receptor subfamily 2, group F, member 6b
chr8_+_31016180 1.11 ENSDART00000130870
ENSDART00000143604
outer dense fiber of sperm tails 2b
chr17_-_33716688 1.10 ENSDART00000043651
dynein, axonemal, light chain 1
chr21_-_29689141 1.10 ENSDART00000100876

chr21_-_29533723 1.10 ENSDART00000193554

chr21_-_29940453 1.09 ENSDART00000182862

chr14_+_30413312 1.09 ENSDART00000186864
CCR4-NOT transcription complex, subunit 7
chr14_-_30905288 1.08 ENSDART00000173449
ENSDART00000173451
si:ch211-126c2.4
chr21_-_29416966 1.08 ENSDART00000162575
zgc:171310
chr21_-_29364166 1.07 ENSDART00000188602

chr18_-_21950751 1.05 ENSDART00000043452
translin-associated factor X interacting protein 1
chr7_+_51795667 1.02 ENSDART00000174201
ENSDART00000073839
solute carrier family 38, member 7
chr2_-_16449504 1.02 ENSDART00000144801
ATR serine/threonine kinase
chr14_+_24840669 1.02 ENSDART00000106039
Rho guanine nucleotide exchange factor (GEF) 37
chr24_-_37272116 1.01 ENSDART00000022999
ubiquitin-conjugating enzyme E2Ib
chr25_-_16755340 1.01 ENSDART00000124729
ENSDART00000110859
RIB43A domain with coiled-coils 2
chr16_+_5901835 0.99 ENSDART00000060519
unc-51 like kinase 4
chr7_+_17908235 0.99 ENSDART00000077113
metastasis associated 1 family, member 2
chr25_+_34845469 0.98 ENSDART00000145416
transmembrane protein 231
chr25_+_3868438 0.98 ENSDART00000156438
transmembrane protein 138
chr10_+_25204626 0.97 ENSDART00000024514
cysteine and histidine-rich domain (CHORD) containing 1b
chr25_+_5755314 0.96 ENSDART00000172088
ENSDART00000164208
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr15_-_23206562 0.96 ENSDART00000110360
coiled-coil domain containing 153
chr14_+_35892802 0.95 ENSDART00000135079
zgc:63568
chr13_+_233482 0.92 ENSDART00000102511
cilia and flagella associated protein 36
chr3_+_60716904 0.92 ENSDART00000168280
forkhead box J1a
chr19_+_14351560 0.91 ENSDART00000182732
AT rich interactive domain 1Ab (SWI-like)
chr5_+_30392148 0.91 ENSDART00000086765
serine/threonine kinase 36 (fused homolog, Drosophila)
chr7_+_41146560 0.88 ENSDART00000143285
ENSDART00000173852
ENSDART00000174003
ENSDART00000038487
ENSDART00000173463
ENSDART00000166448
ENSDART00000052274
poly-U binding splicing factor b
chr13_-_24717618 0.87 ENSDART00000172156
ER lipid raft associated 1
chr12_+_15165736 0.87 ENSDART00000180398
ADP-ribosylarginine hydrolase
chr23_+_24501918 0.86 ENSDART00000078824
SUZ RNA binding domain containing 1
chr7_-_28403930 0.85 ENSDART00000076496
serine/threonine kinase 33
chr8_-_14080534 0.84 ENSDART00000042867
death effector domain containing
chr18_+_2168695 0.84 ENSDART00000165855
dynein axonemal assembly factor 4
chr7_-_41881177 0.83 ENSDART00000174258
ENSDART00000018972
zgc:92818
chr3_-_15144067 0.83 ENSDART00000127738
ENSDART00000060426
ENSDART00000180799
family with sequence similarity 173, member A
chr5_-_66823750 0.83 ENSDART00000041441
ENSDART00000112488
stress-induced phosphoprotein 1
chr7_-_22981796 0.81 ENSDART00000167565
si:dkey-171c9.3
chr17_-_18888959 0.81 ENSDART00000080029
adenylate kinase 7b
chr21_-_32781612 0.80 ENSDART00000031028
CCR4-NOT transcription complex, subunit 6a
chr23_+_12134839 0.80 ENSDART00000128551
ENSDART00000141204
tubulin tyrosine ligase-like family, member 9
chr6_+_18251140 0.80 ENSDART00000169752
coiled-coil domain containing 40
chr1_-_53277187 0.79 ENSDART00000131520
zinc finger protein 330
chr1_-_59216197 0.79 ENSDART00000062426
lysophosphatidic acid receptor 2b
chr17_-_49412313 0.79 ENSDART00000152100
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b
chr24_+_22022109 0.78 ENSDART00000133686
rhophilin associated tail protein 1-like
chr16_-_31791165 0.77 ENSDART00000148389
chromodomain helicase DNA binding protein 4b
chr3_+_28831622 0.77 ENSDART00000184130
ENSDART00000191294
fleer
chr7_+_26549846 0.77 ENSDART00000141353
tyrosine kinase, non-receptor, 1
chr11_+_25328199 0.76 ENSDART00000141478
ENSDART00000112209
family with sequence similarity 83, member D
chr21_-_45348983 0.75 ENSDART00000188017
S-phase kinase-associated protein 1
chr13_-_36703164 0.75 ENSDART00000044357
cyclin-dependent kinase-like 1 (CDC2-related kinase)
chr24_+_22021675 0.75 ENSDART00000081234
rhophilin associated tail protein 1-like
chr24_-_17067284 0.74 ENSDART00000111237
armadillo repeat containing 3
chr10_-_15854743 0.73 ENSDART00000092343
tight junction protein 2a (zona occludens 2)
chr14_+_6954579 0.73 ENSDART00000060998
NME/NM23 family member 5
chr19_+_10661520 0.73 ENSDART00000091813
ENSDART00000165653
argonaute RISC catalytic component 3b
chr23_+_21380079 0.73 ENSDART00000089379
intermediate filament family orphan 2a
chr19_+_9091673 0.73 ENSDART00000052898
si:ch211-81a5.5
chr3_+_52999962 0.72 ENSDART00000104683
pre-B-cell leukemia transcription factor 4
chr25_-_10571078 0.72 ENSDART00000153898
si:ch211-107e6.5
chr13_+_24717880 0.72 ENSDART00000147713
cilia and flagella associated protein 43
chr24_-_10006158 0.71 ENSDART00000106244
zgc:171750
chr14_-_1355544 0.71 ENSDART00000060417
centrin 4
chr7_+_22981441 0.70 ENSDART00000182887
cyclin B3
chr21_+_26726936 0.68 ENSDART00000065392
calmodulin 2a (phosphorylase kinase, delta)
chr7_+_54222156 0.68 ENSDART00000165201
ENSDART00000158518
protein kinase C and casein kinase substrate in neurons 3
chr4_-_71110826 0.68 ENSDART00000167431
si:dkeyp-80d11.1
chr20_+_48116476 0.67 ENSDART00000043938
translocation associated membrane protein 2
chr10_-_17232372 0.67 ENSDART00000135679
RAB36, member RAS oncogene family
chr13_-_6218248 0.67 ENSDART00000159052
si:zfos-1056e6.1
chr17_+_21818093 0.66 ENSDART00000125335
IKAROS family zinc finger 5
chr24_-_38816725 0.66 ENSDART00000063231
noggin 2
chr16_+_37891735 0.65 ENSDART00000178753
ENSDART00000142104
centrosomal protein 162
chr19_+_21266008 0.65 ENSDART00000024639
teashirt zinc finger homeobox 1
chr3_+_21189766 0.64 ENSDART00000078807
zgc:123295
chr16_+_28578352 0.64 ENSDART00000149306
N-myristoyltransferase 2
chr13_+_24679674 0.64 ENSDART00000033090
ENSDART00000139854
zgc:66426
chr1_-_6225285 0.64 ENSDART00000141653
malate dehydrogenase 1B, NAD (soluble)
chr17_-_48805159 0.63 ENSDART00000103662
kinesin family member 6
chr8_-_30242706 0.63 ENSDART00000139864
ENSDART00000143809
zgc:162939
chr14_-_21660548 0.63 ENSDART00000161713
ENSDART00000089845
lysine (K)-specific demethylase 3B
chr1_+_6225493 0.63 ENSDART00000145378
FAST kinase domains 2
chr16_+_41171949 0.62 ENSDART00000135294
NIMA-related kinase 11
chr20_-_4766645 0.62 ENSDART00000147071
ENSDART00000152398
adenylate kinase 7a
chr5_-_24882357 0.61 ENSDART00000127773
ENSDART00000003998
ENSDART00000143851
EWS RNA-binding protein 1b
chr23_+_43950674 0.61 ENSDART00000167813
corin, serine peptidase
chr25_+_35942867 0.61 ENSDART00000066985
hydroxysteroid (17-beta) dehydrogenase 2
chr10_-_24753715 0.61 ENSDART00000192401
integrin-linked kinase
chr5_-_26566435 0.61 ENSDART00000146070
ARVCF, delta catenin family member b
chr15_-_37589600 0.60 ENSDART00000154641
proline and serine rich 3
chr2_+_16449627 0.60 ENSDART00000005381
zgc:110269
chr12_+_11650146 0.60 ENSDART00000150191
WAPL cohesin release factor b
chr18_-_44359726 0.60 ENSDART00000166935
PR domain containing 10
chr2_+_68789 0.58 ENSDART00000058569
claudin 1
chr17_-_24684687 0.58 ENSDART00000105457
MORN repeat containing 2
chr15_+_29085955 0.58 ENSDART00000156799
si:ch211-137a8.4
chr13_-_24717365 0.57 ENSDART00000137934
ENSDART00000003922
ER lipid raft associated 1
chr19_+_28187480 0.57 ENSDART00000183825
iroquois homeobox 4b
chr4_+_48769555 0.55 ENSDART00000150725
zinc finger protein 1020
chr3_+_28831450 0.55 ENSDART00000055422
fleer
chr8_-_22274509 0.55 ENSDART00000181805
ENSDART00000100063
nephronophthisis 4
chr12_+_28955766 0.55 ENSDART00000123417
ENSDART00000139347
zinc finger protein 668
chr7_+_33372680 0.54 ENSDART00000193436
ENSDART00000099988
glucuronic acid epimerase b
chr13_-_18195942 0.54 ENSDART00000079902
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr12_+_6391243 0.54 ENSDART00000152765
protein kinase, cGMP-dependent, type Ib
chr20_-_30900947 0.54 ENSDART00000153419
ENSDART00000062536
heme binding protein 2
chr7_-_40738774 0.54 ENSDART00000084179
ring finger protein 32
chr8_-_22274222 0.53 ENSDART00000131805
nephronophthisis 4
chr18_-_5248365 0.53 ENSDART00000082506
ENSDART00000082504
ENSDART00000097960
myelin expression factor 2
chr1_+_45002971 0.53 ENSDART00000021336
DnaJ (Hsp40) homolog, subfamily A, member 1
chr18_-_49283058 0.53 ENSDART00000076554
si:zfos-464b6.2
chr2_-_59247811 0.53 ENSDART00000141384
finTRIM family, member 32
chr8_-_1266181 0.52 ENSDART00000148654
ENSDART00000149924
cell division cycle 14B
chr17_+_1496107 0.52 ENSDART00000187804

chr15_-_47812268 0.51 ENSDART00000190231
transmembrane O-methyltransferase
chr19_-_5058908 0.51 ENSDART00000130062
chromodomain helicase DNA binding protein 4a
chr11_-_11965033 0.50 ENSDART00000193683
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr24_+_14240196 0.49 ENSDART00000124740
nuclear receptor coactivator 2
chr23_+_29358188 0.49 ENSDART00000189242
TAR DNA binding protein, like
chr8_-_53488832 0.48 ENSDART00000191801
choline dehydrogenase
chr7_+_38395197 0.48 ENSDART00000138669
centrosomal protein 89
chr9_+_52411530 0.47 ENSDART00000163684
NME/NM23 family member 8
chr1_+_58609885 0.47 ENSDART00000186199
si:ch73-236c18.9
chr24_-_36910224 0.47 ENSDART00000079233
dynein, axonemal, assembly factor 3 like
chr13_-_51903150 0.47 ENSDART00000090644
mitochondrial ribosomal protein L2
chr11_+_5499661 0.46 ENSDART00000027850
solute carrier family 35, member E1
chr25_+_3306858 0.46 ENSDART00000137077
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b
chr7_+_21180747 0.46 ENSDART00000185543
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr7_+_52159028 0.46 ENSDART00000014632
ENSDART00000174042
katanin p80 (WD repeat containing) subunit B 1
chr13_-_6323959 0.45 ENSDART00000149619
ENSDART00000148907
microcephalin 1
chr4_+_11690923 0.45 ENSDART00000150624
muskelin 1, intracellular mediator containing kelch motifs
chr1_-_21538673 0.45 ENSDART00000131257
WD repeat domain 19
chr22_-_24738188 0.45 ENSDART00000050238
vitellogenin 1
chr23_-_29357764 0.43 ENSDART00000156512
si:ch211-129o18.4
chr21_-_45349548 0.43 ENSDART00000008454
S-phase kinase-associated protein 1
chr22_+_25049563 0.42 ENSDART00000078173
double zinc ribbon and ankyrin repeat domains 1
chr24_+_36239617 0.42 ENSDART00000062745
RIO kinase 3 (yeast)
chr12_+_1087263 0.42 ENSDART00000160868

chr20_-_46085840 0.42 ENSDART00000133714
trace amine associated receptor 12a
chr3_-_12026741 0.42 ENSDART00000132238
cilia and flagella associated protein 70
chr3_+_60034194 0.42 ENSDART00000189858
ENSDART00000153642

chr19_+_22062202 0.41 ENSDART00000100181
spalt-like transcription factor 3b
chr4_+_57099307 0.41 ENSDART00000131654
si:ch211-238e22.2
chr13_-_9291499 0.40 ENSDART00000146877
si:dkey-33c12.12
chr1_+_22003173 0.40 ENSDART00000054388
dynein, axonemal, heavy chain 6
chr1_-_21538329 0.40 ENSDART00000182798
ENSDART00000193518
ENSDART00000183873
ENSDART00000183376
WD repeat domain 19
chr4_-_178510 0.39 ENSDART00000169805
epidermal growth factor receptor pathway substrate 8
chr15_-_1534232 0.39 ENSDART00000056763
ENSDART00000133943
intraflagellar transport 80 homolog (Chlamydomonas)
chr13_+_9368621 0.39 ENSDART00000109126
Alstrom syndrome protein 1
chr6_+_33537267 0.39 ENSDART00000040334
phosphoinositide-3-kinase, regulatory subunit 3b (gamma)
chr13_-_3155243 0.39 ENSDART00000139183
ENSDART00000050934
protein kinase domain containing, cytoplasmic a
chr2_-_58183499 0.39 ENSDART00000172281
ENSDART00000186262
si:ch1073-185p12.2
chr14_-_35892767 0.39 ENSDART00000052648
transmembrane protein 144b
chr14_+_10596628 0.39 ENSDART00000115177
G protein-coupled receptor 174
chr5_+_36650096 0.38 ENSDART00000111414
alkB homolog 6
chr11_+_37652870 0.38 ENSDART00000129918
kinesin family member 17
chr11_+_1533097 0.37 ENSDART00000066191
intraflagellar transport 52 homolog (Chlamydomonas)
chr17_+_31592191 0.37 ENSDART00000153765
si:dkey-13p1.3

Network of associatons between targets according to the STRING database.

First level regulatory network of rfx7a+rfx7b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.8 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.3 2.8 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.3 0.9 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.3 0.8 GO:0036159 inner dynein arm assembly(GO:0036159)
0.3 3.3 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.3 1.0 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.2 3.2 GO:0021754 facial nucleus development(GO:0021754)
0.2 1.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.2 0.7 GO:1902176 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
0.2 1.0 GO:0018008 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.2 0.9 GO:0060295 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.2 3.0 GO:0032309 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.2 1.7 GO:0036372 opsin transport(GO:0036372)
0.2 1.0 GO:1901207 regulation of heart looping(GO:1901207)
0.2 0.6 GO:0060623 regulation of sister chromatid cohesion(GO:0007063) regulation of chromosome condensation(GO:0060623) regulation of cohesin loading(GO:0071922)
0.2 0.8 GO:0051310 metaphase plate congression(GO:0051310)
0.2 1.5 GO:0048240 sperm capacitation(GO:0048240)
0.2 0.5 GO:0019695 choline metabolic process(GO:0019695)
0.1 5.2 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.1 0.5 GO:0010610 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.1 0.5 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 0.6 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.1 0.7 GO:0003232 bulbus arteriosus development(GO:0003232)
0.1 0.7 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.4 GO:0003352 regulation of cilium movement(GO:0003352)
0.1 0.7 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.1 1.5 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.1 0.7 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.1 1.4 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.6 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.6 GO:0035989 tendon development(GO:0035989)
0.1 1.1 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 2.4 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.1 0.4 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.1 2.4 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.7 GO:0072091 regulation of stem cell proliferation(GO:0072091)
0.1 0.2 GO:0006043 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.1 0.3 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.4 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.1 0.6 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.1 0.6 GO:0051013 microtubule severing(GO:0051013)
0.1 0.9 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 0.2 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 0.4 GO:1903573 IRE1-mediated unfolded protein response(GO:0036498) negative regulation of response to endoplasmic reticulum stress(GO:1903573) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.7 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 0.3 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.1 0.6 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.1 0.7 GO:0014028 notochord formation(GO:0014028)
0.1 0.5 GO:0009217 dGTP catabolic process(GO:0006203) purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dGTP metabolic process(GO:0046070)
0.1 0.4 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.1 0.8 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.1 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 1.0 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.0 0.8 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.5 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 1.0 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.4 GO:0050957 equilibrioception(GO:0050957)
0.0 0.9 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.4 GO:0046457 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.8 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.7 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.4 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.9 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.7 GO:0001649 osteoblast differentiation(GO:0001649)
0.0 0.8 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.9 GO:0042770 signal transduction in response to DNA damage(GO:0042770)
0.0 0.2 GO:1901224 positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 0.4 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.4 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 2.2 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.5 GO:0009408 response to heat(GO:0009408)
0.0 1.1 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 1.6 GO:0009142 nucleoside triphosphate biosynthetic process(GO:0009142)
0.0 1.8 GO:0060215 primitive hemopoiesis(GO:0060215)
0.0 0.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.9 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.1 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.0 0.3 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.3 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 1.2 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 0.5 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.6 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.9 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 0.1 GO:0042539 hypotonic response(GO:0006971) hypotonic salinity response(GO:0042539)
0.0 0.2 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 1.1 GO:0048916 posterior lateral line development(GO:0048916)
0.0 0.3 GO:0061512 protein localization to cilium(GO:0061512)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0005879 axonemal microtubule(GO:0005879)
0.2 0.6 GO:0008352 katanin complex(GO:0008352)
0.2 2.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.2 2.6 GO:0036038 MKS complex(GO:0036038)
0.2 3.1 GO:0097546 ciliary base(GO:0097546)
0.1 0.9 GO:0035060 brahma complex(GO:0035060)
0.1 0.9 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 1.9 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.7 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 1.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 1.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.2 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.1 0.8 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 3.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 1.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.6 GO:0005685 U1 snRNP(GO:0005685)
0.1 0.8 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 3.1 GO:0030286 dynein complex(GO:0030286)
0.1 0.3 GO:0043034 costamere(GO:0043034)
0.1 2.8 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.1 2.1 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 1.0 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.4 GO:0030904 retromer complex(GO:0030904)
0.0 0.5 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.0 2.1 GO:0005814 centriole(GO:0005814)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.8 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.8 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.3 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.4 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.0 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0070735 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.3 1.0 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.3 2.8 GO:0043515 kinetochore binding(GO:0043515)
0.3 0.9 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.3 1.4 GO:0004127 cytidylate kinase activity(GO:0004127)
0.3 1.0 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.2 1.0 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.2 1.6 GO:0030619 U1 snRNA binding(GO:0030619)
0.2 0.6 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 0.8 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 0.5 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.1 0.5 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 0.6 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 1.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 3.0 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 0.4 GO:0071568 UFM1 transferase activity(GO:0071568)
0.1 0.8 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 1.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 2.9 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.5 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.4 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.2 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 1.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.5 GO:0016793 dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793)
0.1 0.7 GO:0035198 miRNA binding(GO:0035198)
0.1 1.1 GO:0031386 protein tag(GO:0031386)
0.1 1.9 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 0.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.4 GO:0045735 nutrient reservoir activity(GO:0045735)
0.1 0.9 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.1 0.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 3.0 GO:0031491 nucleosome binding(GO:0031491)
0.1 0.8 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 3.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.8 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.8 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.7 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.2 GO:0045309 protein phosphorylated amino acid binding(GO:0045309) phosphoprotein binding(GO:0051219)
0.0 1.4 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.8 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.4 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 3.9 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 1.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 1.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.5 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.4 GO:1901476 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 0.2 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.5 GO:0005347 ATP transmembrane transporter activity(GO:0005347)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 1.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.6 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.6 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.5 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.8 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.5 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.4 PID CDC42 PATHWAY CDC42 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 1.0 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 1.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.0 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 1.7 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 1.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 0.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.6 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.6 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.8 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions