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PRJEB1986: zebrafish developmental stages transcriptome

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Results for rbpjb

Z-value: 0.65

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Transcription factors associated with rbpjb

Gene Symbol Gene ID Gene Info
ENSDARG00000052091 recombination signal binding protein for immunoglobulin kappa J region b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rbpjbdr11_v1_chr7_+_62080456_620804560.381.1e-01Click!

Activity profile of rbpjb motif

Sorted Z-values of rbpjb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_22092089 1.31 ENSDART00000101928
crystallin, gamma M2d13
chr14_+_41887070 1.28 ENSDART00000173264
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr20_-_47731768 1.11 ENSDART00000031167
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr9_-_22205682 1.10 ENSDART00000101869
crystallin, gamma M2d12
chr11_+_41981959 1.07 ENSDART00000055707
hairy and enhancer of split-related 15, tandem duplicate 1
chr9_-_22147567 0.99 ENSDART00000110941
crystallin, gamma M2d14
chr1_+_44442140 0.93 ENSDART00000190592
crystallin, beta B1, like 2
chr4_-_5302162 0.86 ENSDART00000177099
si:ch211-214j24.9
chr5_+_10015002 0.75 ENSDART00000140570
solute carrier family 2 (facilitated glucose transporter), member 11b
chr7_+_46252993 0.72 ENSDART00000167149
zinc finger protein 536
chr7_+_31891110 0.72 ENSDART00000173883
myosin binding protein C, cardiac
chr2_-_32769759 0.72 ENSDART00000178951
beaded filament structural protein 2, phakinin
chr15_+_7176182 0.71 ENSDART00000101578
hairy-related 8.2
chr10_+_25982212 0.69 ENSDART00000128292
ENSDART00000108808
Fras1 related extracellular matrix protein 2a
chr23_-_21446985 0.69 ENSDART00000044080
hairy-related 12
chr15_-_37846047 0.63 ENSDART00000184837
heat shock cognate 70
chr15_-_21702317 0.59 ENSDART00000155824
si:dkey-40g16.6
chr19_-_31802296 0.56 ENSDART00000103640
hes-related family bHLH transcription factor with YRPW motif 1
chr23_-_21471022 0.56 ENSDART00000104206
hairy-related 4, tandem duplicate 2
chr3_+_26081343 0.56 ENSDART00000134647
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr21_-_4849029 0.52 ENSDART00000168930
ENSDART00000151019
notch 1a
chr3_+_41917499 0.45 ENSDART00000028673
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr7_-_33960170 0.44 ENSDART00000180766
SKI family transcriptional corepressor 1a
chr16_+_36671064 0.44 ENSDART00000109703
collagen, type VI, alpha 4a
chr9_-_23807032 0.43 ENSDART00000027443
extended synaptotagmin-like protein 3
chr24_-_37877554 0.43 ENSDART00000132219
transmembrane protein 204
chr4_+_19535946 0.42 ENSDART00000192342
ENSDART00000183740
ENSDART00000180812
ENSDART00000180017
leucine rich repeat containing 4.1
chr10_+_3507861 0.42 ENSDART00000092684
rabphilin 3A homolog (mouse), a
chr6_-_14139503 0.42 ENSDART00000089577
calcium channel, voltage-dependent, beta 4b subunit
chr20_+_39283849 0.41 ENSDART00000002481
ENSDART00000146683
scavenger receptor class A, member 3
chr22_+_30335936 0.41 ENSDART00000059923
max interactor 1, dimerization protein
chr2_-_9646857 0.41 ENSDART00000056901
zgc:153615
chr5_-_66028371 0.41 ENSDART00000183012
NOTCH regulated ankyrin repeat protein b
chr3_+_59051503 0.41 ENSDART00000160767
rasd family member 4
chr5_+_9348284 0.40 ENSDART00000149417
T-cell acute lymphocytic leukemia 2
chr1_+_14454663 0.40 ENSDART00000005067
recombination signal binding protein for immunoglobulin kappa J region a
chr4_-_9891874 0.38 ENSDART00000067193
adrenomedullin 2a
chr5_-_22082918 0.37 ENSDART00000020908
zinc finger, C4H2 domain containing
chr3_+_37574885 0.36 ENSDART00000055225
wingless-type MMTV integration site family, member 9B
chr5_-_7834582 0.35 ENSDART00000162626
ENSDART00000157661
PDZ and LIM domain 5a
chr14_+_25817246 0.35 ENSDART00000136733
glycine receptor, alpha 1
chr9_-_22345500 0.33 ENSDART00000101802
crystallin, gamma M2f
chr1_-_45633955 0.33 ENSDART00000044057
septin 3
chr20_+_14789148 0.32 ENSDART00000164761
transmembrane p24 trafficking protein 5
chr11_-_7320211 0.32 ENSDART00000091664
adenomatosis polyposis coli 2
chr20_+_14789305 0.32 ENSDART00000002463
transmembrane p24 trafficking protein 5
chr7_+_39634873 0.32 ENSDART00000114774
protein tyrosine phosphatase, non-receptor type 5
chr11_-_11518469 0.32 ENSDART00000104254
keratin 15
chr3_+_23677351 0.31 ENSDART00000023674
homeobox B9a
chr21_-_5799122 0.31 ENSDART00000129351
ENSDART00000151202
cyclin I
chr8_+_11993150 0.30 ENSDART00000132492
ENSDART00000191519
ENSDART00000114432
netrin g2a
chr25_-_23526058 0.30 ENSDART00000191331
ENSDART00000062930
pleckstrin homology-like domain, family A, member 2
chr20_-_39596338 0.30 ENSDART00000023531
hes-related family bHLH transcription factor with YRPW motif 2
chr7_-_40738774 0.29 ENSDART00000084179
ring finger protein 32
chr7_-_26436436 0.29 ENSDART00000019035
ENSDART00000123395
hairy-related 8a
chr19_-_5254699 0.29 ENSDART00000081951
syntaxin 1B
chr5_-_66028714 0.29 ENSDART00000022625
ENSDART00000164228
NOTCH regulated ankyrin repeat protein b
chr6_+_10333920 0.28 ENSDART00000151667
ENSDART00000151477
cordon-bleu WH2 repeat protein-like 1a
chr18_-_14941840 0.28 ENSDART00000091729
megalencephalic leukoencephalopathy with subcortical cysts 1
chr19_-_32641725 0.28 ENSDART00000165006
ENSDART00000188185
hippocalcin
chr5_-_28679135 0.28 ENSDART00000193585
tenascin C
chr10_-_10863936 0.28 ENSDART00000180568
NOTCH regulated ankyrin repeat protein a
chr20_+_1349043 0.27 ENSDART00000186375
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr8_+_48491387 0.27 ENSDART00000086053
si:ch211-263k4.2
chr10_-_10864331 0.27 ENSDART00000122657
NOTCH regulated ankyrin repeat protein a
chr7_+_53754653 0.27 ENSDART00000163261
ENSDART00000158160
neogenin 1a
chr6_+_30430591 0.26 ENSDART00000108943
shroom family member 2a
chr24_-_37877978 0.26 ENSDART00000128574
transmembrane protein 204
chr13_-_40398556 0.26 ENSDART00000191921
NK3 homeobox 3
chr13_+_11440389 0.26 ENSDART00000186463
zinc finger and BTB domain containing 18
chr5_+_25736979 0.26 ENSDART00000175959
abhydrolase domain containing 17B
chr4_-_15103646 0.25 ENSDART00000138183
ENSDART00000181044
nuclear respiratory factor 1
chr25_+_21178033 0.25 ENSDART00000041169
ELKS/RAB6-interacting/CAST family member 1a
chr7_-_1918971 0.23 ENSDART00000181759

chr24_-_20658446 0.22 ENSDART00000127923
natural killer cell triggering receptor
chr6_+_39923052 0.22 ENSDART00000149019
inositol 1,4,5-trisphosphate receptor, type 1a
chr14_+_35806605 0.22 ENSDART00000173093
glutamate receptor, ionotropic, AMPA 2b
chr4_+_4849789 0.20 ENSDART00000130818
ENSDART00000127751
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr21_-_43485351 0.20 ENSDART00000151597
ankyrin repeat domain 46a
chr16_+_5579744 0.20 ENSDART00000147973
microtubule-actin crosslinking factor 1 b
chr23_-_23401305 0.19 ENSDART00000078936
hairy-related 9
chr16_+_9762261 0.19 ENSDART00000020654
proteasome 26S subunit, non-ATPase 4b
chr25_+_6122823 0.19 ENSDART00000191824
ENSDART00000067514
RNA binding protein with multiple splicing 2a
chr13_-_24874950 0.19 ENSDART00000077775
K(lysine) acetyltransferase 6B
chr10_+_40624702 0.19 ENSDART00000109129
zgc:172131
chr10_+_1668106 0.19 ENSDART00000142278
small G protein signaling modulator 1b
chr22_+_5727753 0.19 ENSDART00000063484
si:dkey-222f2.1
chr18_+_12655766 0.19 ENSDART00000144246
thromboxane A synthase 1 (platelet)
chr25_+_35304903 0.18 ENSDART00000034313
ENSDART00000187659
growth arrest-specific 2a
chr6_-_14292307 0.18 ENSDART00000177852
ENSDART00000061745
inositol polyphosphate-4-phosphatase type I Ab
chr19_+_48018802 0.17 ENSDART00000161339
ENSDART00000166978
si:ch1073-205c8.3
chr2_+_35728033 0.17 ENSDART00000002094
ankyrin repeat domain 45
chr16_+_33953644 0.17 ENSDART00000164447
ENSDART00000159969
AT rich interactive domain 1Aa (SWI-like)
chr19_+_48018464 0.17 ENSDART00000172307
ENSDART00000163848
si:ch1073-205c8.3
chr22_-_11729350 0.17 ENSDART00000105813
keratin 222
chr8_-_41273768 0.17 ENSDART00000108518
ring finger protein 10
chr7_+_17229282 0.17 ENSDART00000097982
solute carrier family 6 (neurotransmitter transporter), member 5
chr8_-_41273461 0.17 ENSDART00000190598
ring finger protein 10
chr4_-_74367912 0.17 ENSDART00000174199
ENSDART00000165257
protein tyrosine phosphatase, receptor type, b
chr2_+_1881334 0.17 ENSDART00000161420
adhesion G protein-coupled receptor L2b, tandem duplicate 1
chr19_-_7540821 0.17 ENSDART00000143958
limb and CNS expressed 1 like
chr10_-_4375190 0.16 ENSDART00000016102

chr3_-_54992934 0.16 ENSDART00000053095
ENSDART00000145766
rhomboid 5 homolog 1a (Drosophila)
chr13_-_27916439 0.16 ENSDART00000139081
ENSDART00000087097
opioid growth factor receptor-like 1
chr7_+_38445938 0.16 ENSDART00000173467
centrosomal protein 89
chr14_+_28486213 0.16 ENSDART00000161852
stromal antigen 2b
chr7_+_53755054 0.16 ENSDART00000181629
neogenin 1a
chr10_-_42297889 0.16 ENSDART00000099262
transcription factor 7 like 1a
chr7_+_62080456 0.16 ENSDART00000092580
recombination signal binding protein for immunoglobulin kappa J region b
chr5_+_62009930 0.15 ENSDART00000082872
A kinase (PRKA) anchor protein 10
chr9_-_22076368 0.15 ENSDART00000128486
crystallin, gamma M2a
chr12_+_19362335 0.15 ENSDART00000041711
G1 to S phase transition 1
chr5_-_56513825 0.15 ENSDART00000024207
T-box 2a
chr7_+_36041509 0.15 ENSDART00000162850
iroquois homeobox 3a
chr1_+_12763920 0.15 ENSDART00000189465
protocadherin 10a
chr22_+_12431608 0.15 ENSDART00000108609
Rho family GTPase 3a
chr16_-_52646789 0.15 ENSDART00000035761
ubiquitin protein ligase E3 component n-recognin 5
chr16_-_21047483 0.15 ENSDART00000136235
chromobox homolog 3b
chr22_+_16308806 0.15 ENSDART00000162685
leucine rich repeat containing 39
chr16_-_27640995 0.14 ENSDART00000019658
NAC alpha domain containing
chr12_+_19362547 0.14 ENSDART00000180148
G1 to S phase transition 1
chr7_+_12950507 0.14 ENSDART00000067629
ENSDART00000158004
serum amyloid A
chr3_-_36839115 0.14 ENSDART00000154553
receptor (G protein-coupled) activity modifying protein 2
chr19_-_20163197 0.13 ENSDART00000148179
ENSDART00000151646
family with sequence similarity 221, member A
chr5_+_34578479 0.13 ENSDART00000016314
G elongation factor, mitochondrial 2
chr6_-_36552844 0.13 ENSDART00000023613
hairy-related 6
chr12_-_15584479 0.13 ENSDART00000150134
acyl-CoA binding domain containing 4
chr25_+_10793478 0.13 ENSDART00000058339
ENSDART00000134923
adaptor-related protein complex 3, sigma 2 subunit
chr16_-_27628994 0.13 ENSDART00000157407
NAC alpha domain containing
chr14_+_16022157 0.12 ENSDART00000167092
neuropeptide Y receptor Y7
chr19_+_42609132 0.12 ENSDART00000010104
cartilage associated protein
chr8_+_21225064 0.12 ENSDART00000129210
cryptochrome circadian clock 1ba
chr11_-_40519886 0.12 ENSDART00000172819
migration and invasion inhibitory protein
chr14_-_33083539 0.12 ENSDART00000160173
discs, large homolog 3 (Drosophila)
chr23_-_36003282 0.12 ENSDART00000103150
calcium binding and coiled-coil domain 1a
chr17_-_27200634 0.11 ENSDART00000185332
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr16_-_21047872 0.11 ENSDART00000131582
chromobox homolog 3b
chr5_+_62009765 0.11 ENSDART00000134335
A kinase (PRKA) anchor protein 10
chr5_-_37252111 0.11 ENSDART00000185110
leucine-rich repeats and calponin homology (CH) domain containing 2
chr25_-_893464 0.11 ENSDART00000159321
zinc finger protein 609a
chr5_+_15202495 0.11 ENSDART00000144915
T-box 1
chr24_-_19718077 0.11 ENSDART00000109107
ENSDART00000056082
cysteine-serine-rich nuclear protein 1b
chr12_+_41991635 0.11 ENSDART00000186161
ENSDART00000192510
transcription elongation regulator 1 like
chr14_+_49152341 0.11 ENSDART00000084114
nuclear receptor binding SET domain protein 1a
chr17_-_6730247 0.11 ENSDART00000031091
visinin-like 1b
chr19_+_19767567 0.10 ENSDART00000169074
homeobox A3a
chr17_+_5061135 0.10 ENSDART00000064313
CDC5 cell division cycle 5-like (S. pombe)
chr4_-_13613148 0.10 ENSDART00000067164
ENSDART00000111247
interferon regulatory factor 5
chr12_-_19862912 0.10 ENSDART00000145788
shisa family member 9a
chr7_+_52712807 0.10 ENSDART00000174095
ENSDART00000174377
ENSDART00000174061
ENSDART00000174094
ENSDART00000110906
ENSDART00000174071
ENSDART00000174238
zinc finger protein 280D
chr23_+_31405497 0.10 ENSDART00000053546
SH3 domain binding glutamate-rich protein like 2
chr13_-_36579086 0.10 ENSDART00000146671
lectin, galactoside binding soluble 3a
chr20_-_54508650 0.10 ENSDART00000147642

chr1_+_10018466 0.09 ENSDART00000113551
tripartite motif containing 2b
chr12_+_21299338 0.09 ENSDART00000074540
ENSDART00000133188
carbonic anhydrase Xa
chr15_-_47468085 0.09 ENSDART00000164438
inositol polyphosphate phosphatase-like 1a
chr14_+_23076207 0.09 ENSDART00000161628
ecto-NOX disulfide-thiol exchanger 2
chr8_-_36554675 0.09 ENSDART00000132804
ENSDART00000078746
coiled-coil domain containing 157
chr6_+_58522557 0.09 ENSDART00000128062
ADP-ribosylation factor related protein 1
chr5_-_2752573 0.09 ENSDART00000168121
leucine zipper, putative tumor suppressor family member 3a
chr8_-_48847772 0.09 ENSDART00000122458
WD repeat containing, antisense to TP73
chr5_-_36597612 0.09 ENSDART00000031270
ENSDART00000122098
ras homolog gene family, member Gc
chr7_-_26462831 0.08 ENSDART00000113543
metallo-beta-lactamase domain containing 1
chr19_-_12648122 0.08 ENSDART00000151184
family with sequence similarity 210, member Aa
chr6_-_49861506 0.08 ENSDART00000121809
GNAS complex locus
chr18_+_41772474 0.08 ENSDART00000097547
transient receptor potential cation channel, subfamily C, member 6b
chr3_+_46315016 0.08 ENSDART00000157199
MKL/myocardin-like 2b
chr14_+_41406321 0.08 ENSDART00000111480
BCL6 corepressor-like 1
chr16_-_17300030 0.08 ENSDART00000149267
Kell blood group, metallo-endopeptidase
chr14_+_38786298 0.08 ENSDART00000164440
si:ch211-195b11.3
chr9_+_2020667 0.07 ENSDART00000157818
limb and neural patterns a
chr14_+_30762131 0.07 ENSDART00000145039
si:ch211-145o7.3
chr2_+_8261109 0.07 ENSDART00000024677
deleted in autism 1a
chr13_-_31389661 0.07 ENSDART00000134630
zinc finger, DHHC-type containing 16a
chr23_-_36003441 0.07 ENSDART00000164699
calcium binding and coiled-coil domain 1a
chr13_-_33246154 0.07 ENSDART00000130127
RTF1 homolog, Paf1/RNA polymerase II complex component
chr25_+_6186823 0.07 ENSDART00000153526
ornithine decarboxylase antizyme 2a
chr8_+_23009662 0.07 ENSDART00000030885
uridine-cytidine kinase 1-like 1a
chr19_-_25113660 0.07 ENSDART00000035538
protein tyrosine phosphatase type IVA, member 3
chr13_-_25305179 0.07 ENSDART00000110064
plasminogen activator, urokinase a
chr18_-_21177674 0.07 ENSDART00000060175
si:dkey-12e7.4
chr3_-_28665291 0.07 ENSDART00000151670
F-box and leucine-rich repeat protein 16
chr17_-_27235797 0.06 ENSDART00000130080
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr25_-_20574859 0.06 ENSDART00000067288
adenosine deaminase-like
chr14_+_8475007 0.06 ENSDART00000148210
DnaJ (Hsp40) homolog, subfamily C, member 4
chr3_+_10637330 0.06 ENSDART00000129257
transmembrane protein 220
chr1_-_51720633 0.06 ENSDART00000045894
ribonuclease H2, subunit A
chr2_+_8112449 0.06 ENSDART00000138136
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2a
chr14_-_4321874 0.06 ENSDART00000042672
GUF1 homolog, GTPase
chr23_+_32011768 0.05 ENSDART00000053509
pleiomorphic adenoma gene X
chr15_+_29362714 0.05 ENSDART00000099916
ENSDART00000126196
guanylate cyclase 2F, retinal
chr23_-_8733092 0.05 ENSDART00000014222
transcription elongation factor A (SII), 2
chr4_-_9722568 0.05 ENSDART00000067190
tetraspanin 9b
chr16_-_13881139 0.05 ENSDART00000138904
ENSDART00000090221
ENSDART00000135099
CDC42 effector protein (Rho GTPase binding) 5
chr22_+_3238474 0.05 ENSDART00000157954
si:ch1073-178p5.3
chr11_+_7580079 0.05 ENSDART00000091550
ENSDART00000193223
ENSDART00000193386
adhesion G protein-coupled receptor L2a
chr12_+_38563073 0.05 ENSDART00000009172
tweety family member 2
chr7_+_19424857 0.04 ENSDART00000173674
si:ch211-212k18.6
chr13_+_31390313 0.04 ENSDART00000111477
ENSDART00000137291
si:dkey-15f17.8
chr19_-_12648408 0.04 ENSDART00000103692
family with sequence similarity 210, member Aa

Network of associatons between targets according to the STRING database.

First level regulatory network of rbpjb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.1 0.7 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 0.6 GO:0090076 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.1 0.6 GO:0072149 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.1 0.5 GO:0055016 hypochord development(GO:0055016)
0.1 0.3 GO:0060844 arterial endothelial cell fate commitment(GO:0060844)
0.1 0.3 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.1 0.2 GO:0070417 cellular response to cold(GO:0070417)
0.1 0.2 GO:0043090 amino acid import(GO:0043090) L-amino acid import(GO:0043092)
0.1 0.9 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.2 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 0.4 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.1 0.3 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.1 GO:0072068 distal convoluted tubule development(GO:0072025) late distal convoluted tubule development(GO:0072068)
0.0 0.2 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.0 0.6 GO:0042026 protein refolding(GO:0042026)
0.0 0.3 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.2 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.0 0.1 GO:0003156 regulation of organ formation(GO:0003156)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 4.2 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.3 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.1 GO:0006953 acute-phase response(GO:0006953)
0.0 0.6 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.4 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.0 0.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 0.3 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.1 GO:1903373 endoplasmic reticulum tubular network maintenance(GO:0071788) regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
0.0 0.1 GO:1900045 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.2 GO:1904950 negative regulation of protein transport(GO:0051224) negative regulation of establishment of protein localization(GO:1904950)
0.0 1.3 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.2 GO:0099558 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.0 0.3 GO:0008105 asymmetric protein localization(GO:0008105) apical protein localization(GO:0045176)
0.0 0.1 GO:0090280 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677) positive regulation of calcium ion import(GO:0090280)
0.0 0.3 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.9 GO:0045103 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.1 GO:0007624 ultradian rhythm(GO:0007624)
0.0 0.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:0021794 thalamus development(GO:0021794)
0.0 0.4 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.4 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0046103 adenosine catabolic process(GO:0006154) inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103)
0.0 1.8 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 0.1 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.0 0.2 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.3 GO:0070831 basement membrane assembly(GO:0070831)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0031673 H zone(GO:0031673)
0.1 0.3 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.3 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.6 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:0098826 endoplasmic reticulum tubular network membrane(GO:0098826)
0.0 0.2 GO:0035060 brahma complex(GO:0035060)
0.0 0.6 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.0 0.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 1.3 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.3 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 4.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.2 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.0 1.4 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.3 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0050780 mu-type opioid receptor binding(GO:0031852) dopamine receptor binding(GO:0050780) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)