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PRJEB1986: zebrafish developmental stages transcriptome

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Results for rbpja

Z-value: 1.10

Motif logo

Transcription factors associated with rbpja

Gene Symbol Gene ID Gene Info
ENSDARG00000003398 recombination signal binding protein for immunoglobulin kappa J region a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rbpjadr11_v1_chr1_+_14454663_144546630.923.0e-08Click!

Activity profile of rbpja motif

Sorted Z-values of rbpja motif

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_45705525 4.60 ENSDART00000148959
endothelin receptor type Ab
chr3_+_41917499 4.05 ENSDART00000028673
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr6_+_30430591 3.70 ENSDART00000108943
shroom family member 2a
chr10_-_10864331 3.07 ENSDART00000122657
NOTCH regulated ankyrin repeat protein a
chr13_-_49819027 2.99 ENSDART00000067824
beta-1,3-N-acetylgalactosaminyltransferase 2
chr23_-_21446985 2.71 ENSDART00000044080
hairy-related 12
chr6_-_9695294 2.63 ENSDART00000162728
NOP58 ribonucleoprotein homolog (yeast)
chr10_-_10863936 2.61 ENSDART00000180568
NOTCH regulated ankyrin repeat protein a
chr1_-_23370395 2.51 ENSDART00000143014
ENSDART00000126785
ENSDART00000159138
PDS5 cohesin associated factor A
chr19_+_42609132 2.47 ENSDART00000010104
cartilage associated protein
chr3_-_25119839 2.42 ENSDART00000154724
chondroadherin-like a
chr3_+_36646054 2.42 ENSDART00000170013
ENSDART00000159948
G1 to S phase transition 1, like
chr16_-_25680666 2.41 ENSDART00000132693
ENSDART00000140539
ENSDART00000015302
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr4_+_21741228 2.40 ENSDART00000112035
ENSDART00000127664
myogenic factor 5
chr4_-_16451375 2.35 ENSDART00000192700
ENSDART00000128835
wu:fc23c09
chr6_-_36552844 2.33 ENSDART00000023613
hairy-related 6
chr23_-_21453614 2.28 ENSDART00000079274
hairy-related 4, tandem duplicate 1
chr19_+_42432625 2.24 ENSDART00000076938
pogo transposable element derived with ZNF domain a
chr8_-_36554675 2.23 ENSDART00000132804
ENSDART00000078746
coiled-coil domain containing 157
chr2_-_32237916 2.08 ENSDART00000141418
family with sequence similarity 49, member Ba
chr20_+_14789148 2.06 ENSDART00000164761
transmembrane p24 trafficking protein 5
chr10_+_38512270 1.97 ENSDART00000109752
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a
chr16_+_40575742 1.95 ENSDART00000161503
cyclin E2
chr21_-_37194365 1.88 ENSDART00000100286
fibroblast growth factor receptor 4
chr10_-_44306636 1.87 ENSDART00000191068
cyclin dependent kinase 2 associated protein 1
chr24_+_18714212 1.84 ENSDART00000171181
centrosome and spindle pole associated protein 1a
chr20_-_39596338 1.83 ENSDART00000023531
hes-related family bHLH transcription factor with YRPW motif 2
chr1_-_51720633 1.82 ENSDART00000045894
ribonuclease H2, subunit A
chr14_-_4321874 1.76 ENSDART00000042672
GUF1 homolog, GTPase
chr16_+_9762261 1.73 ENSDART00000020654
proteasome 26S subunit, non-ATPase 4b
chr6_+_3716666 1.71 ENSDART00000041627
Sjogren syndrome antigen B (autoantigen La)
chr19_-_18127629 1.70 ENSDART00000187722
sorting nexin 10a
chr17_+_16046132 1.59 ENSDART00000155005
si:ch73-204p21.2
chr19_-_18127808 1.59 ENSDART00000108627
sorting nexin 10a
chr5_+_65040228 1.57 ENSDART00000164278
peptidase (mitochondrial processing) alpha
chr6_+_45932276 1.56 ENSDART00000103491
retinol binding protein 7b, cellular
chr17_-_2573021 1.56 ENSDART00000074181
zona pellucida glycoprotein 3, tandem duplicate 2
chr25_+_16646113 1.54 ENSDART00000110426
cat eye syndrome chromosome region, candidate 2
chr3_+_3641429 1.53 ENSDART00000092393
phospholipase B domain containing 1
chr5_-_36597612 1.52 ENSDART00000031270
ENSDART00000122098
ras homolog gene family, member Gc
chr24_+_24170914 1.51 ENSDART00000127842
si:dkey-226l10.6
chr25_+_20272145 1.48 ENSDART00000109605
si:dkey-219c3.2
chr16_+_5579744 1.44 ENSDART00000147973
microtubule-actin crosslinking factor 1 b
chr8_+_15277874 1.44 ENSDART00000146965
deoxynucleotidyltransferase, terminal, interacting protein 2
chr23_+_17839187 1.43 ENSDART00000104647
DNA primase subunit 1
chr21_+_45268112 1.39 ENSDART00000157136
transcription factor 7
chr15_+_9861973 1.36 ENSDART00000170945
si:dkey-13m3.2
chr2_-_48539673 1.33 ENSDART00000168202

chr7_-_41726657 1.32 ENSDART00000099121
ADP-ribosylation factor-like 8
chr21_+_26536950 1.30 ENSDART00000146315
syntaxin 5A, like
chr15_-_6863317 1.30 ENSDART00000155128
ENSDART00000018945
myeloid ecotropic viral integration site 3
chr25_+_2263857 1.29 ENSDART00000076439
tyrosyl-tRNA synthetase 2, mitochondrial
chr16_-_31718013 1.29 ENSDART00000190716
retinol binding protein 1a, cellular
chr23_-_9855627 1.29 ENSDART00000180159
protein kinase C binding protein 1, like
chr10_+_36441124 1.25 ENSDART00000185626
ubiquitin specific peptidase like 1
chr20_+_14789305 1.25 ENSDART00000002463
transmembrane p24 trafficking protein 5
chr16_-_31717851 1.24 ENSDART00000169109
retinol binding protein 1a, cellular
chr21_+_43172506 1.23 ENSDART00000121725
zinc finger, CCHC domain containing 10
chr3_+_31058464 1.23 ENSDART00000153381
si:dkey-66i24.7
chr4_+_45441669 1.22 ENSDART00000150745
si:ch211-162i8.7
chr10_-_44306399 1.20 ENSDART00000180042
cyclin dependent kinase 2 associated protein 1
chr22_-_26274177 1.20 ENSDART00000060978
WD repeat domain containing 83
chr4_+_9030609 1.19 ENSDART00000154399
aldehyde dehydrogenase 1 family, member L2
chr21_+_39673157 1.18 ENSDART00000100240
mitochondrial rRNA methyltransferase 3b
chr25_+_34915576 1.17 ENSDART00000073441
syntrophin, beta 2
chr3_-_3428938 1.16 ENSDART00000179811
ENSDART00000115282
ENSDART00000192263
ENSDART00000046454
zgc:171445
chr18_-_18587745 1.15 ENSDART00000191973
splicing factor 3b, subunit 3
chr24_-_21090447 1.14 ENSDART00000136507
ENSDART00000140786
ENSDART00000184841
queuine tRNA-ribosyltransferase accessory subunit 2
chr18_-_21746421 1.12 ENSDART00000188809
protein serine kinase H1
chr19_+_48018802 1.11 ENSDART00000161339
ENSDART00000166978
si:ch1073-205c8.3
chr11_-_3535537 1.09 ENSDART00000165329
ENSDART00000009788
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (DBP5 homolog, yeast)
chr4_-_41269844 1.08 ENSDART00000186177

chr24_-_20658446 1.08 ENSDART00000127923
natural killer cell triggering receptor
chr13_+_21919786 1.07 ENSDART00000182440
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2a
chr23_+_1730663 1.07 ENSDART00000149545
transglutaminase 1, K polypeptide
chr17_+_5061135 1.05 ENSDART00000064313
CDC5 cell division cycle 5-like (S. pombe)
chr23_-_5783421 1.05 ENSDART00000131521
ENSDART00000019455
cysteine and glycine-rich protein 1a
chr7_+_15329819 1.05 ENSDART00000006018
mesoderm posterior aa
chr16_-_32233463 1.04 ENSDART00000102016
calcium homeostasis modulator family member 6
chr22_-_506522 1.03 ENSDART00000106645
ENSDART00000067637
dual serine/threonine and tyrosine protein kinase
chr1_+_17593392 1.02 ENSDART00000078889
helt bHLH transcription factor
chr4_+_40329524 1.02 ENSDART00000165722
zinc finger protein 993
chr1_+_1805294 1.01 ENSDART00000103850
ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 3
chr22_-_3255341 1.00 ENSDART00000114232
G protein-coupled receptor 35, tandem duplicate 1
chr6_-_52235118 0.99 ENSDART00000191243
translocase of outer mitochondrial membrane 34
chr21_-_27213166 0.99 ENSDART00000146959
MAP/microtubule affinity-regulating kinase 2a
chr16_-_24605969 0.98 ENSDART00000163305
ENSDART00000167121
FXYD domain containing ion transport regulator 6 like
chr6_-_30683637 0.98 ENSDART00000065212
tetratricopeptide repeat domain 4
chr7_+_54475134 0.96 ENSDART00000164063
zgc:153993
chr8_-_39654669 0.96 ENSDART00000145677
si:dkey-63d15.12
chr14_+_743346 0.95 ENSDART00000110511
klotho beta
chr7_-_41338923 0.95 ENSDART00000099138
neutrophil cytosolic factor 2
chr4_-_61406364 0.95 ENSDART00000142592
zinc finger protein 1021
chr17_-_45387134 0.94 ENSDART00000010975
transmembrane protein 206
chr5_+_9246458 0.94 ENSDART00000081772
sushi domain containing 1
chr1_-_54100988 0.92 ENSDART00000192662
regulatory factor X, 1b (influences HLA class II expression)
chr2_-_20923864 0.91 ENSDART00000006870
prostaglandin-endoperoxide synthase 2a
chr25_+_245018 0.91 ENSDART00000155344
zgc:92481
chr17_+_43659940 0.90 ENSDART00000145738
ENSDART00000075619
2-aminoethanethiol (cysteamine) dioxygenase b
chr18_-_46369516 0.90 ENSDART00000018163
interferon regulatory factor 2 binding protein 1
chr20_-_3319642 0.89 ENSDART00000186743
ENSDART00000123096
myristoylated alanine-rich protein kinase C substrate a
chr25_+_245438 0.89 ENSDART00000004689
zgc:92481
chr15_-_23508214 0.88 ENSDART00000115051
ATP-binding cassette, sub-family G (WHITE), member 4b
chr18_+_18612388 0.88 ENSDART00000186455
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr16_-_27161410 0.88 ENSDART00000177503

chr6_+_21005725 0.87 ENSDART00000041370
connexin 44.2
chr5_+_20319519 0.86 ENSDART00000004217
coronin, actin binding protein, 1Ca
chr21_-_32082130 0.85 ENSDART00000003978
ENSDART00000182050
methionine adenosyltransferase II, beta
chr25_+_34915762 0.85 ENSDART00000191776
syntrophin, beta 2
chr8_+_36554816 0.85 ENSDART00000126687
splicing factor 3a, subunit 1
chr23_-_14216506 0.85 ENSDART00000019620
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
chr1_+_57348756 0.85 ENSDART00000063750
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
chr7_+_49681040 0.83 ENSDART00000176372
ENSDART00000192172
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr15_-_6863150 0.82 ENSDART00000153815
myeloid ecotropic viral integration site 3
chr18_-_17075098 0.82 ENSDART00000042496
ENSDART00000192284
ENSDART00000180307
transport and golgi organization 6 homolog (Drosophila)
chr20_-_9199721 0.82 ENSDART00000064140
YLP motif containing 1
chr17_+_32374876 0.81 ENSDART00000183851
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b
chr5_+_4533244 0.81 ENSDART00000158826
Danio rerio thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 1 (LOC561325), mRNA.
chr8_+_23147609 0.78 ENSDART00000180284
GID complex subunit 8 homolog a (S. cerevisiae)
chr9_+_50175366 0.78 ENSDART00000170352
cordon-bleu WH2 repeat protein-like 1b
chr11_-_20956309 0.78 ENSDART00000188659

chr16_+_26449615 0.78 ENSDART00000039746
erythrocyte membrane protein band 4.1b
chr14_+_109016 0.77 ENSDART00000158405
glypican 2
chr21_+_20549395 0.77 ENSDART00000181633
ephrin-A5a
chr17_+_11372531 0.76 ENSDART00000130975
ENSDART00000149366
translocase of inner mitochondrial membrane 9 homolog
chr20_+_53368611 0.75 ENSDART00000060432
cell division cycle 40 homolog (S. cerevisiae)
chr13_-_34781984 0.75 ENSDART00000172138
isthmin 1
chr3_-_7436932 0.72 ENSDART00000163501

chr2_+_8112449 0.72 ENSDART00000138136
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2a
chr19_+_3842891 0.70 ENSDART00000159043
LSM10, U7 small nuclear RNA associated
chr6_-_55423220 0.70 ENSDART00000158929
cathepsin A
chr2_-_38287987 0.68 ENSDART00000185329
ENSDART00000061677
si:ch211-14a17.6
chr16_+_2905150 0.68 ENSDART00000109980
leucyl-tRNA synthetase 2, mitochondrial
chr4_-_60518031 0.68 ENSDART00000157489
si:dkey-211i20.4
chr22_+_567733 0.67 ENSDART00000171036
ubiquitin specific peptidase 49
chr14_+_13454840 0.67 ENSDART00000161854
plastin 3 (T isoform)
chr12_-_4331117 0.67 ENSDART00000008893
carbonic anhydrase XVa
chr7_+_27834130 0.66 ENSDART00000052656
RAS related 2
chr24_+_39027481 0.65 ENSDART00000085565
calpain 15
chr19_+_48018464 0.65 ENSDART00000172307
ENSDART00000163848
si:ch1073-205c8.3
chr17_+_24851951 0.64 ENSDART00000180746
connexin 35.4
chr5_-_29750377 0.63 ENSDART00000051474
BarH-like homeobox 1a
chr19_-_31802296 0.63 ENSDART00000103640
hes-related family bHLH transcription factor with YRPW motif 1
chr5_+_41143563 0.63 ENSDART00000011229
SUB1 homolog, transcriptional regulator b
chr22_+_25049563 0.63 ENSDART00000078173
double zinc ribbon and ankyrin repeat domains 1
chr17_+_6956696 0.63 ENSDART00000171368
zgc:172341
chr19_-_42462491 0.62 ENSDART00000131715
proteasome subunit beta 4
chr24_-_9989634 0.62 ENSDART00000115275
zgc:152652
chr5_-_22082918 0.60 ENSDART00000020908
zinc finger, C4H2 domain containing
chr6_+_58522557 0.60 ENSDART00000128062
ADP-ribosylation factor related protein 1
chr22_+_30335936 0.59 ENSDART00000059923
max interactor 1, dimerization protein
chr12_+_25223843 0.58 ENSDART00000077180
ENSDART00000127454
ENSDART00000122665
metastasis associated 1 family, member 3
chr2_-_38282079 0.58 ENSDART00000145808
si:ch211-10e2.1
chr3_-_41995321 0.57 ENSDART00000192277
tweety family member 3a
chr7_-_17712665 0.57 ENSDART00000149047
multiple endocrine neoplasia I
chr24_+_20658942 0.56 ENSDART00000142848
SEC22 homolog C, vesicle trafficking protein
chr18_-_21640389 0.56 ENSDART00000100857
solute carrier family 38, member 8a
chr20_+_218886 0.55 ENSDART00000002661
laminin, alpha 4
chr24_+_20658760 0.53 ENSDART00000188362
SEC22 homolog C, vesicle trafficking protein
chr12_-_37449396 0.53 ENSDART00000152951
CDC42 effector protein (Rho GTPase binding) 4b
chr22_+_9049179 0.51 ENSDART00000192625
si:ch211-213a13.2
chr4_-_5595237 0.51 ENSDART00000109854
vascular endothelial growth factor Ab
chr7_+_24496894 0.51 ENSDART00000149994
negative elongation factor complex member A
chr8_+_23147218 0.50 ENSDART00000030920
ENSDART00000141175
ENSDART00000146264
GID complex subunit 8 homolog a (S. cerevisiae)
chr10_-_38468847 0.50 ENSDART00000133914
glycerophosphodiester phosphodiesterase domain containing 5a
chr11_-_23322182 0.49 ENSDART00000111289
KiSS-1 metastasis-suppressor
chr13_+_674351 0.48 ENSDART00000111328
cutC copper transporter homolog (E. coli)
chr3_-_36272670 0.48 ENSDART00000141638
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) a
chr22_+_10752787 0.47 ENSDART00000186542
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
chr8_+_12925385 0.47 ENSDART00000085377
zgc:103670
chr3_-_31158382 0.46 ENSDART00000076764
ENSDART00000076796
SMG1 phosphatidylinositol 3-kinase-related kinase
chr3_-_3439150 0.46 ENSDART00000021286
si:dkey-46g23.5
chr5_-_37997774 0.44 ENSDART00000139616
ENSDART00000167694
si:dkey-111e8.1
chr14_-_33521071 0.43 ENSDART00000052789
C1GALT1-specific chaperone 1
chr9_+_23124252 0.42 ENSDART00000192377

chr20_-_54075136 0.42 ENSDART00000074255
mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr11_-_16394971 0.40 ENSDART00000180981
ENSDART00000179925
leucine-rich repeats and immunoglobulin-like domains 1
chr8_+_16726386 0.40 ENSDART00000144621
small integral membrane protein 15
chr7_+_15324830 0.40 ENSDART00000189088
mesoderm posterior aa
chr10_+_31951338 0.39 ENSDART00000019416
LHFPL tetraspan subfamily member 6
chr22_+_21965148 0.38 ENSDART00000136020
si:ch211-207c7.2
chr4_-_74367912 0.38 ENSDART00000174199
ENSDART00000165257
protein tyrosine phosphatase, receptor type, b
chr6_+_58522738 0.38 ENSDART00000157327
ADP-ribosylation factor related protein 1
chr17_-_23416897 0.37 ENSDART00000163391
si:ch211-149k12.3
chr14_+_26229056 0.36 ENSDART00000179045

chr8_-_46386024 0.34 ENSDART00000136602
ENSDART00000060919
ENSDART00000137472
glutaminyl-tRNA synthetase
chr16_-_17300030 0.34 ENSDART00000149267
Kell blood group, metallo-endopeptidase
chr3_+_17616201 0.34 ENSDART00000156775
RAB5C, member RAS oncogene family
chr8_+_26292560 0.33 ENSDART00000053463
monoglyceride lipase
chr11_+_15480695 0.31 ENSDART00000104111
CDK5 regulatory subunit associated protein 1
chr23_-_478201 0.31 ENSDART00000140749
si:ch73-181d5.4
chr14_+_29775602 0.31 ENSDART00000125589
zgc:153146
chr7_-_43787616 0.30 ENSDART00000179758
cadherin 11, type 2, OB-cadherin (osteoblast)
chr3_-_53092509 0.28 ENSDART00000062081
lysophosphatidic acid receptor 2a
chr18_-_5209258 0.28 ENSDART00000183109

chr2_-_59247811 0.27 ENSDART00000141384
finTRIM family, member 32
chr22_-_164944 0.27 ENSDART00000145379
filamin binding LIM protein 1
chr3_-_36750068 0.26 ENSDART00000173388
ATP-binding cassette, sub-family C (CFTR/MRP), member 6b, tandem duplicate 1
chr18_-_18937485 0.26 ENSDART00000139015
si:dkey-73n10.1
chr13_-_50546634 0.25 ENSDART00000192127

Network of associatons between targets according to the STRING database.

First level regulatory network of rbpja

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.7 4.1 GO:0055016 hypochord development(GO:0055016)
0.7 3.3 GO:0070986 left/right axis specification(GO:0070986)
0.7 4.6 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.6 1.9 GO:1904251 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.6 1.8 GO:0060844 arterial endothelial cell fate commitment(GO:0060844)
0.5 2.4 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.4 2.1 GO:1901166 neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.4 1.2 GO:0042560 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.4 1.4 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.3 1.4 GO:0033153 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.3 1.3 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.3 1.8 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.3 3.2 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.3 3.7 GO:0045176 asymmetric protein localization(GO:0008105) apical protein localization(GO:0045176)
0.3 2.3 GO:0021794 thalamus development(GO:0021794)
0.3 1.3 GO:1904867 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576) protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.2 1.4 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.2 0.9 GO:0045730 respiratory burst(GO:0045730)
0.2 0.9 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.2 1.6 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 2.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 2.2 GO:2000344 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 1.4 GO:0048041 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.1 1.0 GO:0060036 notochord cell vacuolation(GO:0060036)
0.1 0.9 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 2.3 GO:0001757 somite specification(GO:0001757)
0.1 1.7 GO:0043248 proteasome assembly(GO:0043248)
0.1 4.4 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.4 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 2.5 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.1 1.8 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 1.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 1.0 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.1 2.2 GO:0008345 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.1 2.6 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.1 2.0 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 1.1 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 1.0 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.1 2.1 GO:0050870 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.1 0.6 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 0.8 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.1 0.7 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 1.0 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 0.2 GO:0019062 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
0.1 0.3 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.5 GO:0035188 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 1.0 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 0.5 GO:0031268 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.9 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 1.5 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 0.5 GO:0097531 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 5.7 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 1.1 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.5 GO:0055070 copper ion homeostasis(GO:0055070)
0.0 0.3 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.7 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.7 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 1.8 GO:0045727 positive regulation of translation(GO:0045727)
0.0 1.3 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 1.5 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 2.4 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 0.5 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.9 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.5 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 1.0 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 1.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.4 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.6 GO:0016203 muscle attachment(GO:0016203)
0.0 0.9 GO:0090148 membrane fission(GO:0090148)
0.0 0.7 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.8 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 1.0 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 1.5 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.2 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 3.5 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 0.5 GO:0033555 multicellular organismal response to stress(GO:0033555)
0.0 0.6 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.6 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.4 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 1.0 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.1 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 1.1 GO:0006400 tRNA modification(GO:0006400)
0.0 3.8 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 4.3 GO:0000398 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 1.4 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.6 GO:0042462 eye photoreceptor cell development(GO:0042462)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.5 2.4 GO:0018444 translation release factor complex(GO:0018444)
0.5 1.4 GO:1990077 primosome complex(GO:1990077)
0.5 1.8 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.4 2.6 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.3 0.8 GO:0031362 intrinsic component of external side of plasma membrane(GO:0031233) anchored component of external side of plasma membrane(GO:0031362)
0.2 2.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.2 0.9 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 1.5 GO:0031010 ISWI-type complex(GO:0031010)
0.1 1.1 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.1 3.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 1.7 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 0.9 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 1.1 GO:0000974 Prp19 complex(GO:0000974)
0.1 2.0 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.3 GO:0015030 Cajal body(GO:0015030)
0.1 3.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 2.9 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 1.5 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 1.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 0.5 GO:0031931 TORC1 complex(GO:0031931)
0.1 4.1 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.1 0.5 GO:0032021 NELF complex(GO:0032021)
0.1 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.8 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.6 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.1 GO:0044216 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.6 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.6 GO:0005839 proteasome core complex(GO:0005839)
0.0 2.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.8 GO:0000922 spindle pole(GO:0000922)
0.0 0.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 2.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 5.8 GO:0000139 Golgi membrane(GO:0000139)
0.0 3.3 GO:0010008 endosome membrane(GO:0010008)
0.0 1.0 GO:0030018 Z disc(GO:0030018)
0.0 1.3 GO:0005882 intermediate filament(GO:0005882)
0.0 1.8 GO:0005759 mitochondrial matrix(GO:0005759)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.7 4.6 GO:0004962 endothelin receptor activity(GO:0004962)
0.4 1.2 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.3 1.8 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3 2.5 GO:0016918 retinal binding(GO:0016918)
0.3 1.3 GO:0032183 SUMO binding(GO:0032183)
0.2 2.4 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2 1.1 GO:0030620 U2 snRNA binding(GO:0030620)
0.2 0.9 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.2 2.4 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.1 1.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 1.6 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 0.7 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 1.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 2.6 GO:0030515 snoRNA binding(GO:0030515)
0.1 0.5 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 4.4 GO:0005518 collagen binding(GO:0005518)
0.1 0.7 GO:0032190 acrosin binding(GO:0032190)
0.1 0.4 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 0.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 1.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.9 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.7 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 1.0 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 2.0 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 1.5 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.1 0.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 3.0 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.1 1.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.3 GO:0031005 filamin binding(GO:0031005)
0.1 1.0 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.6 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 1.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 1.4 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.6 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 1.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.4 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.0 GO:0042805 actinin binding(GO:0042805)
0.0 0.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 17.4 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.6 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 1.5 GO:0043022 ribosome binding(GO:0043022)
0.0 1.4 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 1.9 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.0 0.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 1.0 GO:0031072 heat shock protein binding(GO:0031072)
0.0 1.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.7 GO:0019003 GDP binding(GO:0019003)
0.0 1.2 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 3.3 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 1.8 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 3.7 GO:0051015 actin filament binding(GO:0051015)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 1.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 2.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 3.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 2.8 PID FGF PATHWAY FGF signaling pathway
0.0 0.6 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.1 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.5 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.2 1.9 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.2 3.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.4 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 2.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 0.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 4.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.7 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.0 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.1 2.0 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 2.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 0.7 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 2.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 1.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 0.9 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 0.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 2.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.6 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.8 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.9 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.6 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 1.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation