Project

PRJEB1986: zebrafish developmental stages transcriptome

Navigation
Downloads

Results for prrx1a+prrx1b

Z-value: 1.02

Motif logo

Transcription factors associated with prrx1a+prrx1b

Gene Symbol Gene ID Gene Info
ENSDARG00000033971 paired related homeobox 1a
ENSDARG00000042027 paired related homeobox 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
prrx1bdr11_v1_chr20_+_34511678_345116780.716.2e-04Click!
prrx1adr11_v1_chr2_-_23172708_231727080.213.8e-01Click!

Activity profile of prrx1a+prrx1b motif

Sorted Z-values of prrx1a+prrx1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr25_+_31276842 14.83 ENSDART00000187238
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr1_+_17676745 4.77 ENSDART00000030665
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr9_-_22339582 4.14 ENSDART00000134805
crystallin, gamma M2d1
chr2_+_37227011 2.94 ENSDART00000126587
ENSDART00000084958
sterile alpha motif domain containing 7
chr20_-_43775495 2.83 ENSDART00000100610
ENSDART00000149001
ENSDART00000148809
ENSDART00000100608
matrilin 3a
chr1_-_43905252 2.45 ENSDART00000135477
ENSDART00000132089
si:dkey-22i16.3
chr4_+_9669717 2.41 ENSDART00000004604
si:dkey-153k10.9
chr25_+_29160102 2.22 ENSDART00000162854
pyruvate kinase M1/2b
chr25_+_31277415 2.19 ENSDART00000036275
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr15_+_45640906 2.14 ENSDART00000149361
ENSDART00000149079
S-antigen; retina and pineal gland (arrestin) b
chr11_+_36243774 2.11 ENSDART00000023323
zgc:172270
chr23_-_24343363 2.00 ENSDART00000166392
family with sequence similarity 131, member C
chr15_-_44512461 1.96 ENSDART00000155456
glutamate receptor, ionotropic, AMPA 4a
chr25_+_31227747 1.95 ENSDART00000033872
troponin I type 2a (skeletal, fast), tandem duplicate 1
chr24_-_7697274 1.74 ENSDART00000186077
synaptotagmin Vb
chr7_+_35075847 1.70 ENSDART00000193469
ENSDART00000037346
chymotrypsinogen B1
chr21_+_7582036 1.70 ENSDART00000135485
ENSDART00000027268
orthopedia homeobox a
chr14_+_11430796 1.68 ENSDART00000165275
si:ch211-153b23.3
chr17_-_19345521 1.66 ENSDART00000082085
goosecoid
chr7_+_66822229 1.64 ENSDART00000112109
lymphatic vessel endothelial hyaluronic receptor 1a
chr4_-_14315855 1.62 ENSDART00000133325
neural EGFL like 2b
chr2_+_38039857 1.61 ENSDART00000159951
calsequestrin 1a
chr14_-_49063157 1.58 ENSDART00000021260
septin 8b
chr16_-_45058919 1.58 ENSDART00000177134
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr3_-_31079186 1.57 ENSDART00000145636
ENSDART00000140569
elongin B
elongin B
chr21_-_27881752 1.53 ENSDART00000132583
neurexin 2a
chr6_+_40661703 1.53 ENSDART00000142492
enolase 1b, (alpha)
chr6_+_40354424 1.46 ENSDART00000047416
solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr15_-_16098531 1.46 ENSDART00000080377
aldolase C, fructose-bisphosphate, a
chr9_+_34641237 1.44 ENSDART00000133996
short stature homeobox
chr22_-_910926 1.41 ENSDART00000180075

chr13_+_25449681 1.38 ENSDART00000101328
atonal bHLH transcription factor 7
chr7_-_28148310 1.38 ENSDART00000044208
LIM domain only 1
chr3_-_32337653 1.33 ENSDART00000156918
ENSDART00000156551
si:dkey-16p21.8
chr7_-_13884610 1.31 ENSDART00000006897
retinaldehyde binding protein 1a
chr17_-_16965809 1.29 ENSDART00000153697
neurexin 3a
chr15_+_19797918 1.28 ENSDART00000113314
si:ch211-229d2.5
chr22_+_18389271 1.26 ENSDART00000088270
YjeF N-terminal domain containing 3
chr10_+_29698467 1.25 ENSDART00000163402
discs, large homolog 2 (Drosophila)
chr23_+_45584223 1.25 ENSDART00000149367
si:ch73-290k24.5
chr11_+_27543093 1.24 ENSDART00000023889
BARX homeobox 1
chr10_-_26744131 1.23 ENSDART00000020096
ENSDART00000162710
ENSDART00000179853
fibroblast growth factor 13b
chr16_-_27749172 1.22 ENSDART00000145198
STEAP family member 4
chr19_+_9174166 1.22 ENSDART00000104637
ENSDART00000150968
si:ch211-81a5.8
chr19_+_10339538 1.21 ENSDART00000151808
ENSDART00000151235
recoverin 3
chr7_-_27685365 1.19 ENSDART00000188342
calcitonin/calcitonin-related polypeptide, alpha
chr18_-_16801033 1.19 ENSDART00000100100
adrenomedullin b
chr1_+_37391141 1.18 ENSDART00000083593
ENSDART00000168647
SPARC-like 1
chr21_+_27382893 1.13 ENSDART00000005682
actinin alpha 3a
chr20_-_9462433 1.13 ENSDART00000152674
ENSDART00000040557
zgc:101840
chr1_-_50859053 1.10 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
chr3_-_32170850 1.06 ENSDART00000055307
ENSDART00000157366
troponin T type 1 (skeletal, slow)
chr20_-_44496245 1.06 ENSDART00000012229
FK506 binding protein 1b
chr9_-_46701326 1.05 ENSDART00000159971
si:ch73-193i22.1
chr25_-_210730 1.05 ENSDART00000187580

chr21_+_19008168 1.04 ENSDART00000136196
ENSDART00000128381
ENSDART00000176624
neurofilament, light polypeptide a
chr3_-_24980067 1.03 ENSDART00000048871
desumoylating isopeptidase 1a
chr25_+_26921480 1.00 ENSDART00000155949
glutamate receptor, metabotropic 8b
chr20_-_2134620 0.99 ENSDART00000064375
transmembrane protein 244
chr11_-_37509001 0.99 ENSDART00000109753
bassoon (presynaptic cytomatrix protein) b
chr21_+_26720803 0.98 ENSDART00000053797
solute carrier family 3 (amino acid transporter heavy chain), member 2b
chr1_+_25801648 0.98 ENSDART00000129471
guanylate cyclase 1 soluble subunit beta 1
chr13_-_29421331 0.97 ENSDART00000150228
choline O-acetyltransferase a
chr18_+_8833251 0.95 ENSDART00000143519
IMP (inosine 5'-monophosphate) dehydrogenase 1a
chr18_+_1703984 0.95 ENSDART00000114010
SLIT and NTRK-like family, member 3a
chr3_+_39540014 0.95 ENSDART00000074848
zgc:165423
chr3_+_13440900 0.93 ENSDART00000143715
si:dkey-117i10.1
chr10_-_10607118 0.93 ENSDART00000101089
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr5_+_11407504 0.91 ENSDART00000186723
ENSDART00000018047
zgc:112294
chr15_-_21702317 0.91 ENSDART00000155824
si:dkey-40g16.6
chr17_-_37214196 0.90 ENSDART00000128715
kinesin family member 3Cb
chr23_-_12345764 0.90 ENSDART00000133956
phosphatase and actin regulator 3a
chr10_-_34772211 0.90 ENSDART00000145450
ENSDART00000134307
doublecortin-like kinase 1a
chr25_-_13381854 0.89 ENSDART00000164621
ENSDART00000169129
NDRG family member 4
chr18_-_47662696 0.87 ENSDART00000184260

chr25_+_31267268 0.87 ENSDART00000181239
troponin I type 2a (skeletal, fast), tandem duplicate 3
chr21_-_43022048 0.86 ENSDART00000138329
dihydropyrimidinase-like 3
chr21_+_3093419 0.85 ENSDART00000162520
SHC adaptor protein 3
chr17_+_18117029 0.85 ENSDART00000154646
ENSDART00000179739
B cell CLL/lymphoma 11Ba
chr1_-_10647484 0.84 ENSDART00000164541
ENSDART00000188958
ENSDART00000190904
si:dkey-31e10.1
chr21_+_6556635 0.83 ENSDART00000139598
procollagen, type V, alpha 1
chr25_+_20089986 0.83 ENSDART00000143441
ENSDART00000184073
troponin I4b, tandem duplicate 2
chr18_-_8885792 0.82 ENSDART00000143619
si:dkey-95h12.1
chr12_-_20795867 0.82 ENSDART00000152835
ENSDART00000153424
NME/NM23 nucleoside diphosphate kinase 2a
chr7_+_25858380 0.82 ENSDART00000148780
ENSDART00000079218
myotubularin related protein 1a
chr12_+_42436920 0.82 ENSDART00000177303
early B cell factor 3a
chr21_+_13861589 0.81 ENSDART00000015629
ENSDART00000171306
syntaxin binding protein 1a
chr12_+_18681477 0.81 ENSDART00000127981
ENSDART00000143979
regulator of G protein signaling 9b
chr19_-_5103313 0.81 ENSDART00000037007
triosephosphate isomerase 1a
chr4_+_9279784 0.81 ENSDART00000014897
SLIT-ROBO Rho GTPase activating protein 1b
chr14_+_22152060 0.80 ENSDART00000082697
ENSDART00000054982
gamma-aminobutyric acid (GABA) A receptor, alpha 6a
chr4_-_390431 0.79 ENSDART00000067482
ENSDART00000138500
dynein, light chain, Tctex-type 1
chr14_+_19258702 0.78 ENSDART00000187087
ENSDART00000005738
SLIT and NTRK-like family, member 2
chr20_-_30920356 0.78 ENSDART00000022951
kinesin family member 25
chr6_-_40884453 0.78 ENSDART00000017968
ENSDART00000154100
sirtuin 4
chr12_+_42436328 0.77 ENSDART00000167324
early B cell factor 3a
chr7_-_35515931 0.76 ENSDART00000193324
iroquois homeobox 6a
chr22_+_20208185 0.76 ENSDART00000142748
si:dkey-110c1.7
chr10_-_34741738 0.75 ENSDART00000163072
doublecortin-like kinase 1a
chr16_-_16643377 0.75 ENSDART00000185748
tenascin XBa
chr4_+_2267641 0.75 ENSDART00000165503
si:ch73-89b15.3
chr7_+_26629084 0.74 ENSDART00000101044
ENSDART00000173765
heat shock factor binding protein 1a
chr13_+_24279021 0.72 ENSDART00000058629
actin, alpha 1b, skeletal muscle
chr8_+_2575993 0.72 ENSDART00000112914
si:ch211-51h9.7
chr8_-_18203274 0.71 ENSDART00000134078
ENSDART00000180235
ENSDART00000080006
ENSDART00000125418
ENSDART00000142114
ELOVL fatty acid elongase 8b
chr19_+_31771270 0.71 ENSDART00000147474
stathmin 2b
chr6_+_37894220 0.70 ENSDART00000087311
oculocutaneous albinism II
chr15_-_576135 0.69 ENSDART00000124170
cerebellin 20
chr13_+_31757331 0.69 ENSDART00000044282
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) a
chr9_-_48397702 0.68 ENSDART00000147169
zgc:172182
chr9_+_35876927 0.68 ENSDART00000138834
mab-21-like 3
chr25_+_3327071 0.68 ENSDART00000136131
ENSDART00000133243
lactate dehydrogenase Bb
chr12_-_47601845 0.67 ENSDART00000169548
ENSDART00000182889
regulator of G protein signaling 7b
chr16_-_41439659 0.67 ENSDART00000191624
copine IVa
chr5_-_69180587 0.67 ENSDART00000156681
ENSDART00000160753
zgc:171967
chr19_-_5103141 0.67 ENSDART00000150952
triosephosphate isomerase 1a
chr20_+_34717403 0.66 ENSDART00000034252
prepronociceptin b
chr5_+_36850650 0.65 ENSDART00000051186
non-specific cytotoxic cell receptor protein 1
chr24_-_38384432 0.65 ENSDART00000140739
leucine rich repeat containing 4Bb
chr14_-_34044369 0.64 ENSDART00000149396
ENSDART00000123607
ENSDART00000190746
cytoplasmic FMR1 interacting protein 2
chr2_+_23823622 0.63 ENSDART00000099581
si:dkey-24c2.9
chr16_+_50434668 0.62 ENSDART00000193500
zgc:110372
chr6_+_52350443 0.62 ENSDART00000151612
ENSDART00000151349
si:ch211-239j9.1
chr23_+_34047413 0.61 ENSDART00000143933
ENSDART00000123925
ENSDART00000176139
coiled-coil-helix-coiled-coil-helix domain containing 6a
chr2_-_5505094 0.61 ENSDART00000145035
S-antigen; retina and pineal gland (arrestin) a
chr22_-_15562933 0.61 ENSDART00000141528
ankyrin repeat and MYND domain containing 1
chr24_-_38012593 0.60 ENSDART00000151970
si:ch211-248l17.3
chr25_+_22730490 0.60 ENSDART00000149455
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr18_-_26785861 0.60 ENSDART00000098361
neuromedin Ba
chr23_-_31763753 0.59 ENSDART00000053399
aldehyde dehydrogenase 8 family, member A1
chr2_+_56463167 0.59 ENSDART00000123392
RAB11B, member RAS oncogene family, b
chr3_-_55404985 0.59 ENSDART00000154274
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ga
chr3_+_28953274 0.59 ENSDART00000133528
ENSDART00000103602
lectin, galactoside-binding, soluble, 2a
chr1_-_45553602 0.59 ENSDART00000143664
glutamate receptor, ionotropic, N-methyl D-aspartate 2B, genome duplicate b
chr13_-_49444636 0.58 ENSDART00000136991
interferon regulatory factor 2 binding protein 2a
chr8_-_44868020 0.58 ENSDART00000142712
calcium channel, voltage-dependent, L type, alpha 1F subunit a
chr10_-_33621739 0.58 ENSDART00000142655
ENSDART00000128049
hormonally up-regulated Neu-associated kinase
chr1_+_12009673 0.58 ENSDART00000080100
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr22_-_10121880 0.58 ENSDART00000002348
retinol dehydrogenase 5 (11-cis/9-cis)
chr17_+_46387086 0.57 ENSDART00000157079
si:dkey-206p8.1
chr7_+_20344032 0.57 ENSDART00000144948
ENSDART00000138786
plac8 onzin related protein 1
chr18_+_38321039 0.56 ENSDART00000132534
ENSDART00000111260
ENSDART00000192806
ALX homeobox 4b
chr10_-_17083180 0.55 ENSDART00000170083
family with sequence similarity 166, member B
chr8_+_635704 0.55 ENSDART00000130358
chondroitin sulfate N-acetylgalactosaminyltransferase 1b
chr14_-_17068712 0.54 ENSDART00000170277
paired-like homeobox 2bb
chr17_-_15657029 0.54 ENSDART00000153925
fucosyltransferase 9a
chr12_-_558201 0.54 ENSDART00000168586
ENSDART00000158355
brain specific kinase 146
chr25_-_19648154 0.53 ENSDART00000148570
ATPase plasma membrane Ca2+ transporting 1b
chr12_+_17504559 0.53 ENSDART00000020628
cytohesin 3a
chr2_+_15203322 0.53 ENSDART00000144171
ATP-binding cassette, sub-family A (ABC1), member 4b
chr6_+_8315050 0.53 ENSDART00000189987
glutaryl-CoA dehydrogenase a
chr18_+_5490668 0.52 ENSDART00000167035
muscle-specific beta 1 integrin binding protein 2
chr12_-_25294769 0.52 ENSDART00000153306
hydroxycarboxylic acid receptor 1-4
chr24_+_25069609 0.52 ENSDART00000115165
APC membrane recruitment protein 2
chr8_+_21406769 0.51 ENSDART00000135766
si:dkey-163f12.6
chr12_-_19091214 0.51 ENSDART00000153225
si:ch73-139e5.4
chr22_+_1556948 0.50 ENSDART00000159050
si:ch211-255f4.8
chr9_-_48407408 0.50 ENSDART00000058248
zgc:172182
chr4_+_72578191 0.50 ENSDART00000182434
si:cabz01054394.5
chr13_-_23095006 0.49 ENSDART00000089242
kif1 binding protein
chr8_+_41647539 0.49 ENSDART00000136492
ENSDART00000138799
ENSDART00000134404
si:ch211-158d24.4
chr6_+_23887314 0.49 ENSDART00000163188
zinc finger protein 648
chr25_+_10923100 0.48 ENSDART00000157055
si:ch211-147g22.7
chr7_+_20344222 0.48 ENSDART00000141186
ENSDART00000139274
plac8 onzin related protein 1
chr24_-_25442342 0.48 ENSDART00000177140
ENSDART00000138215
phosphate regulating endopeptidase homolog, X-linked
chr22_+_10698549 0.48 ENSDART00000081228
abhydrolase domain containing 14A
chr23_-_44226556 0.47 ENSDART00000149115
zgc:158659
chr16_+_23984755 0.47 ENSDART00000145328
apolipoprotein C-II
chr23_+_28770225 0.47 ENSDART00000132179
ENSDART00000142273
mannan-binding lectin serine peptidase 2
chr13_-_29505604 0.46 ENSDART00000110005
cadherin-related family member 1a
chr3_+_34919810 0.46 ENSDART00000055264
carbonic anhydrase Xb
chr16_+_20161805 0.45 ENSDART00000192146
chromosome 16 C2orf66 homolog
chr25_-_16146851 0.45 ENSDART00000104043
dickkopf WNT signaling pathway inhibitor 3b
chr23_+_42810055 0.45 ENSDART00000186647
myosin, light chain 9a, regulatory
chr1_+_44814322 0.45 ENSDART00000059227
NADH dehydrogenase (ubiquinone) Fe-S protein 8a
chr1_-_30979707 0.45 ENSDART00000008469
distal-less homeobox 2b
chr3_-_13921173 0.45 ENSDART00000159177
ENSDART00000165174
si:dkey-61n16.5
chr16_-_27640995 0.44 ENSDART00000019658
NAC alpha domain containing
chr3_+_32594357 0.44 ENSDART00000151639
unc-119 lipid binding chaperone B homolog 2
chr13_+_12761707 0.44 ENSDART00000015127
zgc:100846
chr5_+_34407763 0.44 ENSDART00000188849
ENSDART00000145127
laminin, gamma 3
chr14_+_46291022 0.44 ENSDART00000074099
calcium binding protein 2b
chr22_+_14051894 0.44 ENSDART00000142548
aldehyde oxidase 6
chr2_+_30916188 0.44 ENSDART00000137012
myomesin 1a (skelemin)
chr4_-_16345227 0.44 ENSDART00000079521
keratocan
chr18_-_21271373 0.43 ENSDART00000060001
purine nucleoside phosphorylase 6
chr12_+_10631266 0.43 ENSDART00000161455
colony stimulating factor 3 (granulocyte) a
chr24_-_24282427 0.43 ENSDART00000123299
pyruvate dehydrogenase E1 alpha 1 subunit b
chr6_+_29693492 0.43 ENSDART00000114172
phosphodiesterase 6D, cGMP-specific, rod, delta
chr20_+_5106568 0.42 ENSDART00000028039
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 1
chr22_-_23668356 0.42 ENSDART00000167106
ENSDART00000159622
ENSDART00000163228
complement factor H
chr16_-_42872571 0.42 ENSDART00000154757
ENSDART00000102345
thioredoxin interacting protein b
chr16_-_16590780 0.42 ENSDART00000059841
si:ch211-257p13.3
chr1_+_18811679 0.42 ENSDART00000078610
solute carrier family 25, member 51a
chr2_+_20605186 0.42 ENSDART00000128505
olfactomedin-like 2Bb
chr5_-_69180227 0.41 ENSDART00000154816
zgc:171967
chr5_-_11944361 0.41 ENSDART00000165446
ENSDART00000167305
ring finger protein, transmembrane 2
chr14_+_46342882 0.40 ENSDART00000193707
ENSDART00000060577
transmembrane protein 33
chr6_+_49081141 0.40 ENSDART00000131080
ENSDART00000050000
thyroid stimulating hormone, beta subunit, a
chr20_-_46534179 0.39 ENSDART00000060689
eukaryotic translation initiation factor 2B, subunit 2 beta

Network of associatons between targets according to the STRING database.

First level regulatory network of prrx1a+prrx1b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.8 GO:0051503 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.5 1.6 GO:0014809 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.4 21.7 GO:0003009 skeletal muscle contraction(GO:0003009)
0.4 1.2 GO:2000648 positive regulation of stem cell proliferation(GO:2000648)
0.4 1.5 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.3 1.0 GO:0008292 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.3 1.3 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.3 0.9 GO:0046333 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.3 1.2 GO:0015677 copper ion import(GO:0015677)
0.3 1.7 GO:0021767 mammillary body development(GO:0021767) social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.2 1.0 GO:0099543 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.2 0.7 GO:0060292 long term synaptic depression(GO:0060292)
0.2 2.7 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.2 0.9 GO:0061549 sympathetic ganglion development(GO:0061549)
0.2 0.6 GO:0097053 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.2 0.6 GO:1904377 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.2 1.5 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.2 1.6 GO:0031579 membrane raft assembly(GO:0001765) membrane raft organization(GO:0031579) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.2 1.6 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 0.8 GO:0016081 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.1 0.4 GO:0015695 organic cation transport(GO:0015695)
0.1 1.2 GO:0036368 cone photoresponse recovery(GO:0036368)
0.1 0.3 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.1 0.7 GO:2001270 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.7 GO:0042438 melanin biosynthetic process(GO:0042438)
0.1 5.3 GO:0006096 glycolytic process(GO:0006096)
0.1 1.0 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.1 1.7 GO:0010717 regulation of epithelial to mesenchymal transition(GO:0010717)
0.1 0.6 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.1 1.0 GO:0072078 renal tubule morphogenesis(GO:0061333) nephron tubule morphogenesis(GO:0072078) nephron epithelium morphogenesis(GO:0072088)
0.1 1.0 GO:0046037 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.1 0.3 GO:0060879 peripheral nervous system myelin formation(GO:0032290) semicircular canal fusion(GO:0060879)
0.1 1.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.6 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 0.3 GO:0030186 melatonin metabolic process(GO:0030186)
0.1 0.5 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 1.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 1.3 GO:0006825 copper ion transport(GO:0006825)
0.1 0.5 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.1 1.4 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.4 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.1 0.7 GO:0034605 cellular response to heat(GO:0034605)
0.1 0.5 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.3 GO:0033119 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 0.9 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 1.5 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.4 GO:0036268 swimming(GO:0036268)
0.1 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.8 GO:0006183 GTP biosynthetic process(GO:0006183) guanosine-containing compound biosynthetic process(GO:1901070)
0.1 1.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 0.4 GO:2001286 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1 0.3 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.1 1.1 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.4 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.0 0.6 GO:0046887 positive regulation of hormone secretion(GO:0046887)
0.0 0.1 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.0 0.2 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.0 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:0032782 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.0 0.6 GO:0001964 startle response(GO:0001964)
0.0 0.7 GO:0036065 fucosylation(GO:0036065)
0.0 0.6 GO:0042407 cristae formation(GO:0042407)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0071939 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.0 1.1 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 1.2 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.4 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.2 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.6 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.8 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.0 0.4 GO:0060142 regulation of syncytium formation by plasma membrane fusion(GO:0060142)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 1.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.5 GO:0090303 positive regulation of wound healing(GO:0090303)
0.0 0.6 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.2 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 1.4 GO:0036269 swimming behavior(GO:0036269)
0.0 0.4 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.2 GO:0034695 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.0 1.6 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 1.2 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.5 GO:0007398 ectoderm development(GO:0007398)
0.0 0.7 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.7 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.2 GO:0030431 sleep(GO:0030431)
0.0 0.2 GO:1990709 presynaptic active zone organization(GO:1990709)
0.0 0.4 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.3 GO:0097300 necrotic cell death(GO:0070265) programmed necrotic cell death(GO:0097300)
0.0 0.5 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.4 GO:0010257 mitochondrial electron transport, NADH to ubiquinone(GO:0006120) NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 1.4 GO:0030282 bone mineralization(GO:0030282)
0.0 0.8 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.2 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.7 GO:0050868 negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 0.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.7 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 4.5 GO:0007601 visual perception(GO:0007601)
0.0 0.1 GO:1902895 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.4 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.2 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.8 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.4 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.0 1.3 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.1 GO:0070285 pigment cell development(GO:0070285)
0.0 0.5 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.3 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.3 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.4 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.2 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.0 0.7 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.1 GO:0003232 bulbus arteriosus development(GO:0003232)
0.0 0.1 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 1.4 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.5 GO:0051014 actin filament severing(GO:0051014)
0.0 0.4 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.7 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.8 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.2 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.2 GO:0048016 calcineurin-NFAT signaling cascade(GO:0033173) inositol phosphate-mediated signaling(GO:0048016)
0.0 0.0 GO:0050968 chemosensory behavior(GO:0007635) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0 0.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.3 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.5 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.7 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.8 GO:0014904 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 0.5 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 21.7 GO:0005861 troponin complex(GO:0005861)
0.3 1.6 GO:0030891 VCB complex(GO:0030891)
0.2 1.6 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.2 0.8 GO:0005588 collagen type V trimer(GO:0005588)
0.2 1.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.7 GO:0031045 dense core granule(GO:0031045)
0.1 2.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 1.0 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 2.0 GO:0043195 terminal bouton(GO:0043195)
0.1 0.4 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 0.4 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 1.3 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.2 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.1 0.9 GO:0036038 MKS complex(GO:0036038)
0.1 0.4 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.8 GO:0043679 axon terminus(GO:0043679)
0.1 0.6 GO:0061617 MICOS complex(GO:0061617)
0.1 0.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.9 GO:0030667 secretory granule membrane(GO:0030667)
0.1 3.0 GO:0030426 growth cone(GO:0030426)
0.1 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.5 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0030897 HOPS complex(GO:0030897)
0.0 0.7 GO:0005869 dynactin complex(GO:0005869)
0.0 2.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 1.4 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.1 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.0 1.1 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.3 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.2 GO:0038039 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 1.1 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.4 GO:0031430 M band(GO:0031430)
0.0 1.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.0 0.2 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.4 GO:0035869 ciliary transition zone(GO:0035869)
0.0 5.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 1.4 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.2 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.8 GO:0030141 secretory granule(GO:0030141)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.2 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.8 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.4 1.2 GO:0031716 calcitonin receptor binding(GO:0031716)
0.4 1.6 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.4 2.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.4 1.5 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.3 0.9 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.3 1.2 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.3 1.3 GO:0016531 copper chaperone activity(GO:0016531)
0.2 1.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 1.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 1.0 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.4 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1 1.0 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.1 0.6 GO:0071253 connexin binding(GO:0071253)
0.1 0.5 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.1 2.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.7 GO:0004104 cholinesterase activity(GO:0004104)
0.1 0.6 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.3 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 1.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.7 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.9 GO:0016936 galactoside binding(GO:0016936)
0.1 0.5 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.4 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 0.6 GO:0031705 bombesin receptor binding(GO:0031705)
0.1 0.8 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.7 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.5 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.1 1.0 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 0.9 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.4 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.1 1.2 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 0.2 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 1.1 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.5 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.3 GO:0046592 polyamine oxidase activity(GO:0046592)
0.1 0.8 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.1 1.1 GO:0015026 coreceptor activity(GO:0015026)
0.1 1.3 GO:0016854 racemase and epimerase activity(GO:0016854)
0.1 0.7 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 1.0 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.8 GO:0070403 NAD+ binding(GO:0070403)
0.1 1.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.3 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.7 GO:0031628 opioid receptor binding(GO:0031628)
0.0 4.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 1.1 GO:0005523 tropomyosin binding(GO:0005523)
0.0 4.6 GO:0019905 syntaxin binding(GO:0019905)
0.0 1.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.5 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 1.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0015126 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.0 0.6 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.8 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 1.7 GO:0000049 tRNA binding(GO:0000049)
0.0 1.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.5 GO:0051117 ATPase binding(GO:0051117)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.3 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.1 GO:0004776 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.0 0.2 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0001729 ceramide kinase activity(GO:0001729)
0.0 0.8 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.2 GO:0034632 retinol transporter activity(GO:0034632)
0.0 0.3 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 1.9 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 1.1 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0015105 arsenite transmembrane transporter activity(GO:0015105)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.5 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.9 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.2 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.2 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.3 GO:0030552 cAMP binding(GO:0030552)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 1.8 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0016917 GABA receptor activity(GO:0016917)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.0 GO:0072570 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.0 2.3 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 1.2 GO:0005179 hormone activity(GO:0005179)
0.0 2.3 GO:0042393 histone binding(GO:0042393)
0.0 0.2 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 PID CONE PATHWAY Visual signal transduction: Cones
0.1 0.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.7 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.8 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.2 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.1 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.3 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 4.8 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 0.9 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 0.8 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.8 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.6 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 1.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.5 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 1.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 2.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions