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PRJEB1986: zebrafish developmental stages transcriptome

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Results for pou4f3_pou4f1+pou4f4

Z-value: 1.62

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Transcription factors associated with pou4f3_pou4f1+pou4f4

Gene Symbol Gene ID Gene Info
ENSDARG00000006206 POU class 4 homeobox 3
ENSDARG00000005559 POU class 4 homeobox 1
ENSDARG00000044375 zgc
ENSDARG00000111929 zgc

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou4f3dr11_v1_chr9_+_54290896_542908960.789.0e-05Click!
pou4f1dr11_v1_chr6_+_4539953_45399530.253.0e-01Click!
zgc:158291dr11_v1_chr21_+_38312549_38312549-0.039.1e-01Click!

Activity profile of pou4f3_pou4f1+pou4f4 motif

Sorted Z-values of pou4f3_pou4f1+pou4f4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_30620625 8.05 ENSDART00000098273
transcobalamin like
chr11_+_6819050 7.64 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr19_-_10196370 6.90 ENSDART00000091707
D site albumin promoter binding protein a
chr17_+_2162916 5.88 ENSDART00000103775
p21 protein (Cdc42/Rac)-activated kinase 6a
chr7_-_69298271 5.73 ENSDART00000122935
PH domain and leucine rich repeat protein phosphatase 2
chr1_-_21901589 5.29 ENSDART00000140553
FERM and PDZ domain containing 1a
chr20_-_40754794 5.10 ENSDART00000187251
connexin 32.3
chr2_+_39108339 5.00 ENSDART00000085675
calsyntenin 2
chr5_+_51079504 4.95 ENSDART00000097466
family with sequence similarity 169, member Aa
chr23_-_27345425 4.93 ENSDART00000022042
ENSDART00000191870
sodium channel, voltage gated, type VIII, alpha subunit a
chr5_-_30418636 4.67 ENSDART00000098285
activating transcription factor 5a
chr25_-_4148719 4.58 ENSDART00000112880
ENSDART00000023278
fatty acid desaturase 2
chr24_-_4765740 4.53 ENSDART00000121576
carboxypeptidase B1 (tissue)
chr25_-_13614702 4.47 ENSDART00000165510
ENSDART00000190959
fatty acid 2-hydroxylase
chr7_-_34225011 4.45 ENSDART00000049588
crystallin beta gamma X
chr20_+_9355912 4.38 ENSDART00000142337
si:dkey-174m14.3
chr5_-_23429228 4.22 ENSDART00000049291
glutamate receptor, ionotropic, AMPA 3a
chr4_+_12111154 4.07 ENSDART00000036779
transmembrane protein 178B
chr16_+_14029283 3.89 ENSDART00000146165
ENSDART00000132075
RUN and SH3 domain containing 1
chr20_-_31808779 3.85 ENSDART00000133788
syntaxin binding protein 5a (tomosyn)
chr6_-_39489190 3.85 ENSDART00000151299
sodium channel, voltage gated, type VIII, alpha subunit b
chr25_+_28679672 3.57 ENSDART00000139965
ENSDART00000134072
CCR4-NOT transcription complex, subunit 2
chr16_-_49505275 3.29 ENSDART00000160784
SATB homeobox 1b
chr5_+_58372164 3.28 ENSDART00000057910
neurogranin (protein kinase C substrate, RC3) a
chr16_-_12953739 3.27 ENSDART00000103894
calcium channel, voltage-dependent, gamma subunit 8b
chr6_+_21740672 3.26 ENSDART00000193734
lipoma HMGIC fusion partner-like 4a
chr13_-_43599898 3.24 ENSDART00000084416
ENSDART00000145705
actin binding LIM protein 1a
chr6_+_45494227 3.18 ENSDART00000159863
contactin 4
chr2_+_25929619 3.15 ENSDART00000137746
solute carrier family 7, member 14a
chr10_+_38775408 3.10 ENSDART00000125045
Down syndrome cell adhesion molecule a
chr9_-_22213297 3.04 ENSDART00000110656
ENSDART00000133149
crystallin, gamma M2d20
chr17_-_37395460 3.00 ENSDART00000148160
ENSDART00000075975
cysteine-rich protein 1
chr20_+_22045089 3.00 ENSDART00000063564
ENSDART00000187013
ENSDART00000161552
ENSDART00000174478
ENSDART00000063568
ENSDART00000152247
neuromedin U
chr22_+_5687615 2.98 ENSDART00000133241
ENSDART00000019854
ENSDART00000138102
deoxyribonuclease 1 like 4, tandem duplicate 2
chr2_-_43196595 2.93 ENSDART00000141087
cAMP responsive element modulator a
chr20_-_44575103 2.85 ENSDART00000192573
UBX domain protein 2A
chr16_+_16849220 2.84 ENSDART00000047409
ENSDART00000142155
myosin, heavy chain 14, non-muscle
chr21_-_13123176 2.77 ENSDART00000144866
ENSDART00000024616
family with sequence similarity 219, member Aa
chr23_-_29376859 2.71 ENSDART00000146411
somatostatin 6
chr20_-_34801181 2.67 ENSDART00000048375
ENSDART00000132426
stathmin-like 4
chr23_-_24195723 2.65 ENSDART00000145489
anoctamin 11
chr1_-_15797663 2.64 ENSDART00000177122
sarcoglycan zeta
chr22_+_15507218 2.59 ENSDART00000125450
glypican 1a
chr16_+_10776688 2.58 ENSDART00000161969
ENSDART00000172657
ATPase Na+/K+ transporting subunit alpha 3b
chr22_-_2959005 2.58 ENSDART00000040701
inhibitor of growth family, member 5a
chr6_-_35446110 2.56 ENSDART00000058773
regulator of G protein signaling 16
chr25_+_24291156 2.51 ENSDART00000083407
beta-1,4-N-acetyl-galactosaminyl transferase 4a
chr11_+_23760470 2.39 ENSDART00000175688
ENSDART00000121874
ENSDART00000086720
neurofascin homolog (chicken) a
chr25_-_13614863 2.36 ENSDART00000121859
fatty acid 2-hydroxylase
chr14_-_18672561 2.35 ENSDART00000166730
ENSDART00000006998
SLIT and NTRK-like family, member 4
chr5_-_30074332 2.34 ENSDART00000147963
beta-carotene oxygenase 2a
chr19_-_3574060 2.33 ENSDART00000105120
transmembrane protein 170B
chr16_-_45398408 2.31 ENSDART00000004052
ral guanine nucleotide dissociation stimulator-like 2
chr11_-_38083397 2.27 ENSDART00000086516
ENSDART00000184033
kelch domain containing 8A
chr10_-_10018120 2.16 ENSDART00000132375
spermatid perinuclear RNA binding protein
chr9_+_38481780 2.15 ENSDART00000087241
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr10_+_38775959 2.14 ENSDART00000192990
Down syndrome cell adhesion molecule a
chr21_+_27278120 2.13 ENSDART00000193882
si:dkey-175m17.7
chr13_+_28702104 2.09 ENSDART00000135481
si:ch211-67n3.9
chr10_+_25726694 2.08 ENSDART00000140308
UDP glucuronosyltransferase 5 family, polypeptide D1
chr8_-_22838364 1.98 ENSDART00000187954
ENSDART00000185368
ENSDART00000188210
MAGI family member, X-linked a
chr12_+_2446837 1.97 ENSDART00000112032
si:dkey-191m6.4
chr11_+_37137196 1.86 ENSDART00000172950
WNK lysine deficient protein kinase 2
chr13_+_45524475 1.83 ENSDART00000074567
ENSDART00000019113
macoilin 1b
chr8_-_20230559 1.82 ENSDART00000193677
MLLT1, super elongation complex subunit a
chr17_-_20287530 1.81 ENSDART00000078703
ENSDART00000191289
adducin 3 (gamma) b
chr24_-_26622423 1.78 ENSDART00000182044
TRAF2 and NCK interacting kinase b
chr5_-_68058168 1.76 ENSDART00000177026
ring finger protein 167
chr2_+_50608099 1.75 ENSDART00000185805
ENSDART00000111135
neuronal differentiation 6b
chr20_+_41664350 1.74 ENSDART00000186247
family with sequence similarity 184, member A
chr8_+_7975745 1.74 ENSDART00000137920
si:ch211-169p10.1
chr23_-_24195519 1.72 ENSDART00000112370
ENSDART00000180377
anoctamin 11
chr18_+_15616167 1.72 ENSDART00000080454
solute carrier family 17 (vesicular glutamate transporter), member 8
chr13_-_17860307 1.71 ENSDART00000135920
ENSDART00000054579
membrane-associated ring finger (C3HC4) 8
chr13_-_49666615 1.67 ENSDART00000148083
translocase of outer mitochondrial membrane 20
chr24_+_14713776 1.64 ENSDART00000134475
ganglioside induced differentiation associated protein 1
chr2_+_22702488 1.62 ENSDART00000076647
kinesin family member 1Ab
chr7_+_73397283 1.60 ENSDART00000174390

chr11_-_38513978 1.59 ENSDART00000123381
si:ch211-117k10.3
chr15_-_14552101 1.59 ENSDART00000171169
numb homolog (Drosophila)-like
chr3_-_23407720 1.57 ENSDART00000155658
Rap guanine nucleotide exchange factor (GEF)-like 1
chr12_-_26406323 1.55 ENSDART00000131896
myozenin 1b
chr2_-_31651297 1.55 ENSDART00000132955
si:ch211-106h4.9
chr23_-_18024543 1.54 ENSDART00000139695
peptidase M20 domain containing 1, tandem duplicate 1
chr18_-_47662696 1.53 ENSDART00000184260

chr16_-_38118003 1.52 ENSDART00000058667
si:dkey-23o4.6
chr23_+_6232895 1.50 ENSDART00000139795
synaptotagmin IIa
chr7_-_71829649 1.50 ENSDART00000160449
calcium channel, voltage-dependent, beta 2a
chr3_+_26734162 1.44 ENSDART00000114552
si:dkey-202l16.5
chr20_+_31076488 1.43 ENSDART00000136255
ENSDART00000008840
otoferlin a
chr23_+_20689255 1.42 ENSDART00000182420
ubiquitin specific peptidase 21
chr20_-_48172556 1.41 ENSDART00000097888

chr17_-_51893123 1.40 ENSDART00000103350
ENSDART00000017329
numb homolog (Drosophila)
chr13_+_8604710 1.36 ENSDART00000091097
suppressor of cytokine signaling 5b
chr6_+_38427570 1.34 ENSDART00000170612
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr23_-_27692717 1.33 ENSDART00000053878
ENSDART00000145028
si:dkey-166n8.9
chr11_-_1956204 1.32 ENSDART00000185541
nuclear receptor subfamily 1, group D, member 4b
chr3_-_28048475 1.31 ENSDART00000150888
RNA binding fox-1 homolog 1
chr17_+_31914877 1.30 ENSDART00000177801
family with sequence similarity 196 member A
chr24_-_3419998 1.28 ENSDART00000066839
solute carrier family 35, member G2b
chr7_-_49892991 1.27 ENSDART00000126240
CD44 molecule (Indian blood group) a
chr9_-_68934 1.25 ENSDART00000054594
ENSDART00000009389
interleukin 10 receptor, beta
chr12_-_26537145 1.24 ENSDART00000138437
ENSDART00000163931
ENSDART00000132737
acyl-CoA synthetase family member 2
chr17_+_15983247 1.24 ENSDART00000154275
calmin
chr1_+_44491077 1.24 ENSDART00000073736
reticulon 4 receptor-like 2 a
chr11_+_44356504 1.23 ENSDART00000160678
serine/arginine-rich splicing factor 7b
chr8_+_668184 1.22 ENSDART00000183788
ring finger protein 165b
chr13_-_21688176 1.22 ENSDART00000063825
shadow of prion protein
chr3_-_61336841 1.21 ENSDART00000155414
tectonin beta-propeller repeat containing 1b
chr23_-_30431333 1.20 ENSDART00000146633
calmodulin binding transcription activator 1a
chr24_+_3328354 1.20 ENSDART00000147468
3-hydroxybutyrate dehydrogenase, type 1
chr6_+_4299164 1.18 ENSDART00000159759
neurobeachin-like 1
chr23_+_21966447 1.18 ENSDART00000189378
lactamase, beta-like 1a
chr10_+_42423318 1.17 ENSDART00000134282
neuropeptide Y receptor Y8a
chr13_+_12299997 1.16 ENSDART00000108535
gamma-aminobutyric acid (GABA) A receptor, beta 1
chr6_+_3280939 1.14 ENSDART00000151359
lysine (K)-specific demethylase 4A, genome duplicate a
chr9_+_22388686 1.13 ENSDART00000182731
ENSDART00000181462
diacylglycerol kinase, gamma
chr3_-_23406964 1.11 ENSDART00000114723
Rap guanine nucleotide exchange factor (GEF)-like 1
chr1_+_36665555 1.10 ENSDART00000128557
ENSDART00000010632
endothelin receptor type Aa
chr9_-_18735256 1.10 ENSDART00000143165
TSC22 domain family, member 1
chr7_+_27976448 1.09 ENSDART00000181026
tubby bipartite transcription factor
chr2_-_48171112 1.09 ENSDART00000156258
phosphofructokinase, platelet b
chr15_+_45586471 1.09 ENSDART00000165699
claudin 15-like b
chr11_+_19060079 1.09 ENSDART00000158123
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr16_+_29630965 1.06 ENSDART00000185820
ENSDART00000192105
ENSDART00000153683
ENSDART00000186713
si:ch211-203d17.1
chr2_-_50966124 1.05 ENSDART00000170470
growth hormone releasing hormone receptor a
chr13_+_31757331 1.05 ENSDART00000044282
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) a
chr6_-_41229787 1.05 ENSDART00000065013
synaptoporin
chr9_-_40931637 1.05 ENSDART00000165103
Small membrane A-kinase anchor protein
chr11_+_23957440 1.04 ENSDART00000190721
contactin 2
chr3_-_34717882 1.03 ENSDART00000151127
thyroid hormone receptor alpha a
chr3_-_28665291 1.02 ENSDART00000151670
F-box and leucine-rich repeat protein 16
chr7_-_12371206 1.01 ENSDART00000161679
elongation factor like GTPase 1
chr13_-_32635859 1.00 ENSDART00000146249
ENSDART00000145395
ENSDART00000148040
ENSDART00000100650
matrilin 3b
chr4_+_6869847 0.99 ENSDART00000036646
dedicator of cytokinesis 4b
chr11_-_45135643 0.98 ENSDART00000170863
calcium activated nucleotidase 1b
chr11_+_44356707 0.96 ENSDART00000165219
serine/arginine-rich splicing factor 7b
chr20_-_2361226 0.95 ENSDART00000172130
si:ch73-18b11.1
chr9_+_11034967 0.95 ENSDART00000152081
acid-sensing (proton-gated) ion channel family member 4a
chr7_+_3357973 0.94 ENSDART00000172853
si:ch211-285c6.5
chr15_+_32297441 0.94 ENSDART00000153657
tripartite motif containing 3a
chr6_+_8079974 0.93 ENSDART00000152071
si:ch211-207j7.2
chr7_-_28148310 0.91 ENSDART00000044208
LIM domain only 1
chr10_+_40214877 0.89 ENSDART00000109689
GRAM domain containing 1Ba
chr13_-_39830999 0.87 ENSDART00000115089
zgc:171482
chr23_+_33907899 0.85 ENSDART00000159445
citrate synthase
chr10_+_19528321 0.85 ENSDART00000184816
V-set and immunoglobulin domain containing 8a
chr17_+_33999630 0.83 ENSDART00000167085
ENSDART00000155030
ENSDART00000168522
ENSDART00000191799
ENSDART00000189684
ENSDART00000153942
ENSDART00000187272
ENSDART00000127692
gephyrin a
chr22_-_32360464 0.83 ENSDART00000148886
poly(rC) binding protein 4
chr20_+_27298783 0.83 ENSDART00000013861
protein phosphatase 4, regulatory subunit 4
chr9_+_7030016 0.82 ENSDART00000148047
ENSDART00000148181
inositol polyphosphate-4-phosphatase type I Aa
chr1_+_31113951 0.82 ENSDART00000129362
eukaryotic translation elongation factor 1 alpha 1b
chr25_+_8407892 0.81 ENSDART00000153536
mucin 5.2
chr17_+_15983557 0.81 ENSDART00000190806
calmin
chr12_-_30523216 0.81 ENSDART00000152896
ENSDART00000153191
pleckstrin homology domain containing, family S member 1
chr14_-_7207961 0.80 ENSDART00000167994
ENSDART00000166532
storkhead box 2b
chr10_+_5645887 0.79 ENSDART00000171426
PDZ and pleckstrin homology domains 1
chr20_-_43663494 0.79 ENSDART00000144564

chr7_+_53156810 0.78 ENSDART00000189816
cadherin 29
chr1_-_43899422 0.77 ENSDART00000134649
si:dkey-22i16.2
chr5_+_4054704 0.77 ENSDART00000140537
dehydrogenase/reductase (SDR family) member 11a
chr22_-_20379045 0.76 ENSDART00000183511
zinc finger and BTB domain containing 7a
chr8_-_27858458 0.76 ENSDART00000132632
ENSDART00000136562
CTTNBP2 N-terminal like b
chr7_+_47316944 0.76 ENSDART00000173534
dpy-19 like C-mannosyltransferase 3
chr12_+_20618336 0.75 ENSDART00000084007
si:dkey-220f10.4
chr18_+_40355408 0.75 ENSDART00000167134
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like
chr13_+_36622100 0.73 ENSDART00000133198
si:ch211-67f24.7
chr21_+_170038 0.69 ENSDART00000157614
kelch-like family member 8
chr11_+_36409457 0.68 ENSDART00000077641
cytochrome b561 family, member D1
chr12_-_33893381 0.67 ENSDART00000153280
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Gb
chr1_+_25783801 0.66 ENSDART00000102455
guanylate cyclase 1 soluble subunit alpha 1
chr19_-_43552252 0.66 ENSDART00000138308
G protein-coupled receptor 186
chr20_-_39333657 0.66 ENSDART00000153720
ENSDART00000142164
chemokine (C-C motif) ligand 38, duplicate 1
chr3_-_30434016 0.65 ENSDART00000150958
leucine rich repeat containing 4Ba
chr11_+_34523132 0.64 ENSDART00000192257
zinc finger, matrin-type 3
chr22_-_14475927 0.64 ENSDART00000135768
low density lipoprotein receptor-related protein 1Ba
chr21_+_5882300 0.63 ENSDART00000165065
ubiquinol-cytochrome c reductase, complex III subunit X
chr8_-_39952727 0.61 ENSDART00000181310
calcium binding protein 1a
chr24_+_36840652 0.61 ENSDART00000088168

chr3_+_22578369 0.61 ENSDART00000187695
ENSDART00000182678
ENSDART00000112270
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2a
chr16_-_31351419 0.60 ENSDART00000178298
ENSDART00000018091
maestro heat-like repeat family member 1
chr1_+_38758261 0.60 ENSDART00000182756
WD repeat domain 17
chr2_-_9818640 0.59 ENSDART00000139499
ENSDART00000165548
ENSDART00000012442
ENSDART00000046587
adaptor-related protein complex 2, mu 1 subunit, b
chr8_-_23884301 0.57 ENSDART00000185509
ENSDART00000147202
LHFPL tetraspan subfamily member 5b
chr23_+_41831224 0.56 ENSDART00000171885
sterol carrier protein 2b
chr13_-_16066997 0.54 ENSDART00000184790
spermatogenesis associated 48
chr12_+_20618522 0.54 ENSDART00000091452
si:dkey-220f10.4
chr7_+_27317174 0.53 ENSDART00000193058
SRY (sex determining region Y)-box 6
chr2_+_45511459 0.52 ENSDART00000132101
AKNA domain containing 1
chr4_+_9669717 0.52 ENSDART00000004604
si:dkey-153k10.9
chr16_+_1353894 0.51 ENSDART00000148426
cugbp, Elav-like family member 3b
chr11_+_30057762 0.51 ENSDART00000164139
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr10_+_44824072 0.46 ENSDART00000162669
solute carrier family 4 (sodium bicarbonate cotransporter), member 5
chr9_-_10532591 0.46 ENSDART00000175269
thrombospondin, type I, domain containing 7Ba
chr1_+_38758445 0.46 ENSDART00000136300
WD repeat domain 17
chr20_-_40766387 0.45 ENSDART00000061173
hydroxysteroid dehydrogenase like 1
chr11_-_25777318 0.45 ENSDART00000079328
phospholipase C, eta 2b
chr22_+_30517227 0.44 ENSDART00000170978
si:dkey-103k4.1
chr20_-_11178022 0.43 ENSDART00000152246
fibronectin leucine rich transmembrane protein 2
chr7_+_6941583 0.43 ENSDART00000160709
ENSDART00000157634
RNA binding motif protein 14b

Network of associatons between targets according to the STRING database.

First level regulatory network of pou4f3_pou4f1+pou4f4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.6 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
1.2 4.9 GO:0007638 mechanosensory behavior(GO:0007638)
1.0 4.1 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
1.0 3.0 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.4 4.4 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.4 1.7 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.4 2.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.4 1.5 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.4 1.8 GO:0023041 neuronal signal transduction(GO:0023041)
0.4 3.6 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.3 1.0 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.3 1.0 GO:0042256 mature ribosome assembly(GO:0042256)
0.3 1.1 GO:0010155 regulation of proton transport(GO:0010155)
0.3 2.3 GO:0046247 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.3 4.4 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.3 0.8 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.2 3.8 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.2 3.0 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.2 1.7 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.2 3.3 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.2 5.2 GO:0070593 dendrite self-avoidance(GO:0070593)
0.2 3.0 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.2 2.9 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.2 0.8 GO:0033119 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 3.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 3.7 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.1 2.6 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 2.6 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.1 1.4 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 0.3 GO:0042730 fibrinolysis(GO:0042730)
0.1 1.9 GO:0010765 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 0.6 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.1 0.6 GO:0032370 positive regulation of lipid transport(GO:0032370)
0.1 0.8 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 1.0 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.1 3.3 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 1.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 1.1 GO:0061718 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 3.3 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.1 3.9 GO:0050708 regulation of protein secretion(GO:0050708)
0.1 10.8 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.1 0.8 GO:0060612 adipose tissue development(GO:0060612)
0.1 0.7 GO:0090594 inflammatory response to wounding(GO:0090594)
0.1 1.2 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.1 2.1 GO:0016114 terpenoid biosynthetic process(GO:0016114)
0.1 1.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.2 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.1 1.4 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.1 0.6 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 8.0 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 0.2 GO:0070257 regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
0.1 2.7 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 2.4 GO:0061512 protein localization to cilium(GO:0061512)
0.1 0.9 GO:0014823 response to activity(GO:0014823)
0.0 0.2 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.0 1.1 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 4.5 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 1.1 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.2 GO:1901380 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 1.8 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.3 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.4 GO:0006566 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.0 0.4 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.0 1.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 1.4 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 1.3 GO:0021854 hypothalamus development(GO:0021854)
0.0 3.2 GO:0006865 amino acid transport(GO:0006865)
0.0 0.9 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 1.4 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 1.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 2.2 GO:0007283 spermatogenesis(GO:0007283)
0.0 0.2 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 1.7 GO:0042552 myelination(GO:0042552)
0.0 1.9 GO:0070374 positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.0 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.3 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.9 GO:0009755 hormone-mediated signaling pathway(GO:0009755)
0.0 1.9 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.0 2.4 GO:0030334 regulation of cell migration(GO:0030334)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0060077 inhibitory synapse(GO:0060077)
0.4 8.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.3 1.5 GO:0042584 chromaffin granule membrane(GO:0042584)
0.3 3.6 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.2 7.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 1.7 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 2.6 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 1.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.7 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 2.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 1.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 1.0 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 1.8 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 2.5 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 0.6 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 3.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 4.0 GO:0031201 SNARE complex(GO:0031201)
0.1 1.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.6 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 8.7 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 1.2 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.8 GO:0016459 myosin complex(GO:0016459)
0.0 1.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.5 GO:0005902 microvillus(GO:0005902)
0.0 1.5 GO:0005811 lipid particle(GO:0005811)
0.0 1.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 6.4 GO:0030424 axon(GO:0030424)
0.0 0.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.6 GO:0030018 Z disc(GO:0030018)
0.0 1.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.8 GO:1903293 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 8.7 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.4 GO:0016607 nuclear speck(GO:0016607)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.8 GO:0080132 fatty acid alpha-hydroxylase activity(GO:0080132)
0.5 2.5 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.4 1.2 GO:0004904 interferon receptor activity(GO:0004904)
0.4 9.9 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.4 1.2 GO:0031956 medium-chain fatty acid-CoA ligase activity(GO:0031956) butyrate-CoA ligase activity(GO:0047760)
0.3 3.0 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.3 4.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.3 0.8 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.3 2.3 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.3 2.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.2 3.9 GO:0045159 myosin II binding(GO:0045159)
0.2 4.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 5.2 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.2 1.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.2 3.3 GO:0050811 GABA receptor binding(GO:0050811)
0.2 1.6 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.2 1.5 GO:0004046 aminoacylase activity(GO:0004046)
0.2 2.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 1.7 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.1 1.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.8 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 1.9 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1 2.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 0.9 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 1.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.4 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 7.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.4 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.1 2.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 3.0 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.2 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.1 2.4 GO:0035064 methylated histone binding(GO:0035064)
0.1 1.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 0.4 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 4.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 1.5 GO:0017022 myosin binding(GO:0017022)
0.1 1.7 GO:0042287 MHC protein binding(GO:0042287)
0.0 1.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 2.6 GO:0005254 chloride channel activity(GO:0005254)
0.0 2.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 1.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 1.1 GO:0017046 peptide hormone binding(GO:0017046)
0.0 1.0 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 2.2 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.3 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 2.9 GO:0043130 ubiquitin binding(GO:0043130)
0.0 3.2 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 4.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 2.6 GO:0019905 syntaxin binding(GO:0019905)
0.0 3.3 GO:0005179 hormone activity(GO:0005179)
0.0 0.6 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.8 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 9.1 GO:0051015 actin filament binding(GO:0051015)
0.0 1.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.0 GO:0043022 ribosome binding(GO:0043022)
0.0 3.3 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.5 GO:0016229 steroid dehydrogenase activity(GO:0016229)
0.0 2.3 GO:0042277 peptide binding(GO:0042277)
0.0 5.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 4.3 GO:0003924 GTPase activity(GO:0003924)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.9 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.4 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.4 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.2 PID EPHA FWDPATHWAY EPHA forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 3.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.2 2.8 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 2.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 2.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.4 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 3.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.0 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 2.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases