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PRJEB1986: zebrafish developmental stages transcriptome

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Results for pou3f1

Z-value: 0.92

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Transcription factors associated with pou3f1

Gene Symbol Gene ID Gene Info
ENSDARG00000009823 POU class 3 homeobox 1
ENSDARG00000112302 POU class 3 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou3f1dr11_v1_chr16_+_33593116_33593116-0.391.0e-01Click!

Activity profile of pou3f1 motif

Sorted Z-values of pou3f1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_30563115 3.13 ENSDART00000028566
si:ch211-200p22.4
chr13_-_7031033 2.84 ENSDART00000193211

chr16_-_12173554 2.84 ENSDART00000110567
ENSDART00000155935
calsyntenin 3
chr15_+_45640906 2.73 ENSDART00000149361
ENSDART00000149079
S-antigen; retina and pineal gland (arrestin) b
chr18_-_42830563 2.57 ENSDART00000191488
tetratricopeptide repeat domain 36
chr6_+_41096058 2.52 ENSDART00000028373
FK506 binding protein 5
chr16_-_43971258 2.37 ENSDART00000141941
zinc finger protein, FOG family member 2a
chr14_+_32839535 2.15 ENSDART00000168975
arrestin 3b, retinal (X-arrestin)
chr9_-_9980704 2.06 ENSDART00000130243
ENSDART00000193475
UDP glucuronosyltransferase 1 family a, b
chr7_-_24699985 2.01 ENSDART00000052802
calbindin 2b
chr6_+_4539953 1.98 ENSDART00000025031
POU class 4 homeobox 1
chr23_+_36771593 1.89 ENSDART00000078240
membrane-associated ring finger (C3HC4) 9
chr6_-_16406210 1.88 ENSDART00000012023
Fas apoptotic inhibitory molecule b
chr17_+_15882533 1.87 ENSDART00000164124
gamma-aminobutyric acid (GABA) A receptor, rho 2a
chr22_+_20195280 1.83 ENSDART00000088603
ENSDART00000135692
si:dkey-110c1.7
chr23_+_44307996 1.79 ENSDART00000042430
discs, large homolog 4b (Drosophila)
chr6_-_13187168 1.76 ENSDART00000193286
ENSDART00000188350
ENSDART00000150036
ENSDART00000149940
ADAM metallopeptidase domain 23a
chr9_-_31915423 1.74 ENSDART00000060051
fibroblast growth factor 14
chr16_-_12173399 1.71 ENSDART00000142574
calsyntenin 3
chr21_-_27185915 1.70 ENSDART00000135052
solute carrier family 8 (sodium/calcium exchanger), member 4a
chr20_-_25542183 1.70 ENSDART00000024350
cytochrome P450, family 2, subfamily AD, polypeptide 2
chr13_+_33117528 1.65 ENSDART00000085719
si:ch211-10a23.2
chr19_-_28367413 1.64 ENSDART00000079092
si:dkey-261i16.5
chr11_-_44876005 1.60 ENSDART00000192006
opsin 6, group member a
chr9_-_18877597 1.57 ENSDART00000099446
potassium channel tetramerization domain containing 4
chr1_+_1599979 1.50 ENSDART00000097626
urotensin II-related peptide
chr22_+_18389271 1.50 ENSDART00000088270
YjeF N-terminal domain containing 3
chr12_+_48480632 1.48 ENSDART00000158157
Rho GTPase activating protein 44
chr4_-_8903240 1.48 ENSDART00000129983
metallophosphoesterase domain containing 1
chr5_-_16996482 1.43 ENSDART00000144501
polypeptide N-acetylgalactosaminyltransferase 9
chr2_-_34555945 1.43 ENSDART00000056671
bone morphogenetic protein/retinoic acid inducible neural-specific 2
chr5_-_42272517 1.41 ENSDART00000137692
ENSDART00000164363
si:ch211-207c6.2
chr5_-_24238733 1.38 ENSDART00000138170
phospholipid scramblase 3a
chr25_-_16057539 1.38 ENSDART00000090388
cytochrome b5 reductase 2
chr7_-_38633867 1.37 ENSDART00000137424
C1q and TNF related 4
chr14_+_36889893 1.36 ENSDART00000124159
si:ch211-132p1.3
chr25_-_13188678 1.34 ENSDART00000125754
si:ch211-147m6.1
chr4_-_9592402 1.31 ENSDART00000114060
cerebral dopamine neurotrophic factor
chr18_+_660578 1.31 ENSDART00000161203
si:dkey-205h23.2
chr21_+_41743493 1.28 ENSDART00000192669
protein phosphatase 2, regulatory subunit B, beta b
chr2_+_24203229 1.28 ENSDART00000138088
microtubule associated protein 4 like
chr22_+_5106751 1.27 ENSDART00000138967
ataxia, cerebellar, Cayman type a
chr3_-_32337653 1.26 ENSDART00000156918
ENSDART00000156551
si:dkey-16p21.8
chr6_-_13188667 1.26 ENSDART00000191654
ADAM metallopeptidase domain 23a
chr11_+_25634041 1.25 ENSDART00000033657
glutamate receptor, metabotropic 6b
chr6_+_23935045 1.25 ENSDART00000162993
growth arrest and DNA-damage-inducible, alpha, b
chr19_-_32042105 1.24 ENSDART00000088358
zinc finger protein 704
chr5_-_24000211 1.22 ENSDART00000188865
MAP7 domain containing 2a
chr20_+_18225329 1.21 ENSDART00000144172
potassium channel tetramerization domain containing 1
chr23_+_28731379 1.18 ENSDART00000047378
cortistatin
chr5_-_25406807 1.18 ENSDART00000089748
RAR-related orphan receptor B
chr16_+_45746549 1.17 ENSDART00000190403
progestin and adipoQ receptor family member VI
chr10_+_26972755 1.15 ENSDART00000042162
transmembrane 7 superfamily member 2
chr22_+_14051894 1.15 ENSDART00000142548
aldehyde oxidase 6
chr6_+_9867426 1.13 ENSDART00000151749
si:ch211-222n4.6
chr24_-_24983047 1.13 ENSDART00000066631
solute carrier family 51, alpha subunit
chr10_+_453619 1.11 ENSDART00000135598
zinc finger, DHHC-type containing 8a
chr5_+_27429872 1.11 ENSDART00000087894
zgc:165555
chr15_-_30815826 1.11 ENSDART00000156160
ENSDART00000145918
musashi RNA-binding protein 2b
chr25_+_27923846 1.10 ENSDART00000047007
solute carrier family 13 member 1
chr2_+_55982940 1.10 ENSDART00000097753
ENSDART00000097751
nicotinamide riboside kinase 2
chr12_+_46960579 1.10 ENSDART00000149032
ornithine aminotransferase
chr10_-_35103208 1.08 ENSDART00000192734
zgc:110006
chr3_-_32817274 1.07 ENSDART00000142582
myosin light chain, phosphorylatable, fast skeletal muscle a
chr20_+_40150612 1.06 ENSDART00000143680
ENSDART00000109681
ENSDART00000101041
ENSDART00000121818
triadin
chr22_-_18491813 1.05 ENSDART00000105419
si:ch211-212d10.2
chr23_+_28582865 1.04 ENSDART00000020296
L1 cell adhesion molecule, paralog a
chr2_+_30147504 1.04 ENSDART00000190947
potassium voltage-gated channel, Shab-related subfamily, member 2
chr18_-_36135799 1.04 ENSDART00000059344
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) a
chr7_+_13824150 1.02 ENSDART00000035067
abhydrolase domain containing 2a
chr24_-_40009446 0.99 ENSDART00000087422
amine oxidase, copper containing 1
chr4_+_12292274 0.96 ENSDART00000061070
ENSDART00000150786
makorin, ring finger protein, 1
chr18_+_7286788 0.95 ENSDART00000022998
si:ch73-86n2.1
chr22_-_7400471 0.95 ENSDART00000161215
si:dkey-57c15.1
chr2_+_32835679 0.91 ENSDART00000132767
PX domain containing 1a
chr10_+_22003750 0.91 ENSDART00000109420
Kv channel interacting protein 1 b
chr25_-_25736958 0.91 ENSDART00000166308
calcium and integrin binding family member 2
chr8_+_13503377 0.91 ENSDART00000034740
ENSDART00000167187
fucosyltransferase 9d
chr21_-_13662237 0.90 ENSDART00000091647
ENSDART00000151547
patatin-like phospholipase domain containing 7a
chr10_-_24689725 0.89 ENSDART00000079566
si:ch211-287a12.9
chr13_+_30951155 0.86 ENSDART00000057469
ENSDART00000162254
V-set and transmembrane domain containing 4a
chr12_-_28983584 0.86 ENSDART00000112374
zgc:171713
chr8_-_15398760 0.83 ENSDART00000162011
ATP/GTP binding protein-like 4
chr4_-_16644708 0.82 ENSDART00000042307
SIN3-HDAC complex associated factor
chr19_+_3001473 0.78 ENSDART00000145363
scleraxis bHLH transcription factor a
chr5_+_30384554 0.77 ENSDART00000135483
zgc:158412
chr6_+_45692026 0.76 ENSDART00000164759
contactin 4
chr10_+_33744098 0.75 ENSDART00000147775
relaxin/insulin-like family peptide receptor 2a
chr25_-_19666107 0.72 ENSDART00000149889
ATPase plasma membrane Ca2+ transporting 1b
chr19_+_14573998 0.72 ENSDART00000022076
family with sequence similarity 46, member Bb
chr4_+_12013043 0.71 ENSDART00000130692
cryptochrome circadian clock 1aa
chr8_+_31777633 0.71 ENSDART00000142519
3-oxoacid CoA transferase 1a
chr3_-_3209432 0.70 ENSDART00000140635
si:ch211-229i14.2
chr15_-_5157572 0.69 ENSDART00000174192
odorant receptor, family E, subfamily 128, member 10
chr4_+_12013642 0.68 ENSDART00000067281
cryptochrome circadian clock 1aa
chr2_+_2563192 0.68 ENSDART00000055713

chr19_-_8096984 0.67 ENSDART00000146987
si:dkey-266f7.9
chr20_+_35998073 0.67 ENSDART00000140457
opsin 5
chr25_-_26673570 0.67 ENSDART00000154917
circadian associated repressor of transcription b
chr17_-_30473374 0.67 ENSDART00000155021
si:ch211-175f11.5
chr22_+_24645325 0.67 ENSDART00000159531
lysophosphatidic acid receptor 3
chr13_-_49444636 0.65 ENSDART00000136991
interferon regulatory factor 2 binding protein 2a
chr20_+_27298783 0.63 ENSDART00000013861
protein phosphatase 4, regulatory subunit 4
chr10_+_44940693 0.63 ENSDART00000157515
cyclin and CBS domain divalent metal cation transport mediator 4a
chr19_-_30562648 0.63 ENSDART00000171006
hippocalcin like 4
chr15_+_39096736 0.62 ENSDART00000129511
ENSDART00000014877
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr22_-_38516922 0.59 ENSDART00000151257
ENSDART00000151785
kinesin light chain 4
chr17_+_33719415 0.59 ENSDART00000132294
fucosyltransferase 8a (alpha (1,6) fucosyltransferase)
chr15_+_42933236 0.58 ENSDART00000167763
solute carrier family 8 (sodium/calcium exchanger), member 2b
chr25_+_20188769 0.58 ENSDART00000142781
caldesmon 1b
chr7_-_6466119 0.57 ENSDART00000173138
zgc:112234
chr22_+_18786797 0.56 ENSDART00000141864
calcium channel, voltage-dependent, beta subunit associated regulatory protein b
chr20_-_39188476 0.56 ENSDART00000152858
regulator of calcineurin 2
chr22_+_17784414 0.56 ENSDART00000188189
ENSDART00000145260
transmembrane 6 superfamily member 2
chr9_-_18735256 0.55 ENSDART00000143165
TSC22 domain family, member 1
chr14_+_23874062 0.55 ENSDART00000172149
SH3 domain containing ring finger 2
chr16_+_39159752 0.54 ENSDART00000122081
syntabulin (syntaxin-interacting)
chr7_+_69470442 0.54 ENSDART00000189593
GABA(A) receptor-associated protein b
chr12_+_36092218 0.54 ENSDART00000168694
BTB (POZ) domain containing 17a
chr25_+_35067318 0.54 ENSDART00000186828

chr21_+_8427059 0.54 ENSDART00000143151
DENN/MADD domain containing 1A
chr7_+_61050329 0.54 ENSDART00000115355
NACHT and WD repeat domain containing 2
chr11_+_769623 0.54 ENSDART00000172972
vestigial-like family member 4b
chr5_+_30624183 0.53 ENSDART00000141444
ATP-binding cassette, sub-family G (WHITE), member 4a
chr7_-_4036184 0.53 ENSDART00000019949
NDRG family member 2
chr4_+_20255160 0.50 ENSDART00000188658
leucine-rich repeats and transmembrane domains 2a
chr10_+_26973063 0.50 ENSDART00000143162
ENSDART00000186210
transmembrane 7 superfamily member 2
chr7_+_66739166 0.49 ENSDART00000154634
murine retrovirus integration site 1 homolog
chr7_+_5906327 0.49 ENSDART00000173160
zgc:112234
chr7_+_27455321 0.49 ENSDART00000148417
cytochrome P450, family 2, subfamily R, polypeptide 1
chr5_-_46896541 0.49 ENSDART00000133240
EGF-like repeats and discoidin I-like domains 3a
chr10_+_36458563 0.48 ENSDART00000077008
arachidonate 5-lipoxygenase-activating protein
chr10_-_5821584 0.48 ENSDART00000166388
interleukin 6 signal transducer
chr5_+_29820266 0.47 ENSDART00000146331
ENSDART00000098315
F11 receptor, tandem duplicate 2
chr5_+_5398966 0.47 ENSDART00000139553
mitogen-activated protein kinase associated protein 1
chr7_-_6351021 0.47 ENSDART00000159542
zgc:112234
chr23_-_893547 0.47 ENSDART00000136805
RNA binding motif protein 10
chr21_-_35853245 0.47 ENSDART00000172245
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr11_-_41130239 0.46 ENSDART00000173268
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr18_-_49286381 0.45 ENSDART00000174248
ENSDART00000174038
si:zfos-464b6.2
chr2_-_39036604 0.45 ENSDART00000129963
retinol binding protein 1b, cellular
chr4_-_15603511 0.44 ENSDART00000122520
ENSDART00000162356
coiled-coil-helix-coiled-coil-helix domain containing 3a
chr2_-_3616363 0.42 ENSDART00000144699
phosphotriesterase related
chr16_+_40560622 0.42 ENSDART00000038294
tumor protein p53 inducible nuclear protein 1
chr19_-_19556778 0.41 ENSDART00000164060
Tax1 (human T-cell leukemia virus type I) binding protein 1a
chr3_+_47322494 0.41 ENSDART00000102202
phosphatidic acid phosphatase type 2D
chr20_-_39735952 0.40 ENSDART00000101049
ENSDART00000137485
ENSDART00000062402
tumor protein D52-like 1
chr14_-_16810401 0.40 ENSDART00000158396
ENSDART00000170758
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b
chr9_+_45227028 0.40 ENSDART00000185579
adenosine deaminase, RNA-specific, B1b
chr8_-_12403077 0.39 ENSDART00000142150
PHD finger protein 19
chr18_-_47103131 0.39 ENSDART00000188553

chr13_+_42406883 0.39 ENSDART00000084354
cytoplasmic polyadenylation element binding protein 3
chr25_+_36674715 0.38 ENSDART00000111861
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog b (paralog b)
chr10_+_33393829 0.37 ENSDART00000163458
ENSDART00000115379
zgc:153345
chr15_+_34592215 0.37 ENSDART00000099776
tetraspanin 13a
chr20_-_45060241 0.37 ENSDART00000185227
kelch-like family member 29
chr21_-_30254185 0.37 ENSDART00000101054
DnaJ (Hsp40) homolog, subfamily C, member 18
chr22_-_20376488 0.36 ENSDART00000140187
zinc finger and BTB domain containing 7a
chr6_-_52644182 0.35 ENSDART00000015051
growth differentiation factor 5
chr21_-_25573064 0.33 ENSDART00000134310

chr15_-_734203 0.33 ENSDART00000177867
ENSDART00000154918
si:dkey-7i4.21

chr6_-_13308813 0.33 ENSDART00000065372
potassium inwardly-rectifying channel, subfamily J, member 3b
chr7_+_10701938 0.33 ENSDART00000158162
aryl-hydrocarbon receptor nuclear translocator 2
chr17_-_15528597 0.33 ENSDART00000150232
FYN proto-oncogene, Src family tyrosine kinase a
chr3_+_26223376 0.32 ENSDART00000128284
nudix (nucleoside diphosphate linked moiety X)-type motif 9
chr17_-_32865788 0.31 ENSDART00000077476
prospero homeobox 1a
chr18_-_35390735 0.31 ENSDART00000098297

chr3_+_33345348 0.30 ENSDART00000059262
membrane protein, palmitoylated 2a (MAGUK p55 subfamily member 2)
chr25_+_5604512 0.30 ENSDART00000042781
plexin b2b
chr8_+_18044257 0.30 ENSDART00000029255
GLIS family zinc finger 1b
chr24_+_41931585 0.29 ENSDART00000130310
erythrocyte membrane protein band 4.1-like 3a
chr15_-_4023182 0.29 ENSDART00000190195

chr17_-_24916889 0.29 ENSDART00000156157
si:ch211-195o20.7
chr1_-_16394814 0.29 ENSDART00000013024
fibroblast growth factor 20a
chr14_+_6991142 0.28 ENSDART00000157635
ENSDART00000059918
heterogeneous nuclear ribonucleoprotein H1
chr16_-_31756859 0.28 ENSDART00000149170
ENSDART00000126617
ENSDART00000182722
protein tyrosine phosphatase, non-receptor type 6
chr1_-_55068941 0.28 ENSDART00000152143
ENSDART00000152590
pellino E3 ubiquitin protein ligase 1a
chr7_+_31074636 0.28 ENSDART00000173805
tight junction protein 1a
chr25_-_13202208 0.28 ENSDART00000168155
si:ch211-194m7.4
chr2_+_8779164 0.28 ENSDART00000134308
zinc finger, ZZ-type containing 3
chr9_-_25444091 0.27 ENSDART00000002428
activin A receptor type 2Aa
chr1_+_8984068 0.27 ENSDART00000122568
toll-like receptor 2
chr19_-_6239248 0.27 ENSDART00000014127
POU class 2 homeobox 2a
chr23_-_6765653 0.26 ENSDART00000192310

chr25_+_14694876 0.26 ENSDART00000050478
ENSDART00000188093
metallophosphoesterase domain containing 2b
chr9_+_54695981 0.25 ENSDART00000183605
RAB9A, member RAS oncogene family
chr7_+_44593756 0.25 ENSDART00000125365
si:ch211-189a15.5
chr3_+_16922226 0.24 ENSDART00000017646
ATPase H+ transporting V0 subunit a1a
chr7_-_33921366 0.24 ENSDART00000052397
protein inhibitor of activated STAT, 1a
chr22_-_32392252 0.23 ENSDART00000148681
ENSDART00000137945
poly(rC) binding protein 4
chr19_+_30990129 0.22 ENSDART00000052169
ENSDART00000193376
syncoilin, intermediate filament protein
chr5_+_22970617 0.22 ENSDART00000192859
high mobility group nucleosomal binding domain 7
chr2_-_56131312 0.21 ENSDART00000097755
JunD proto-oncogene, AP-1 transcription factor subunit
chr10_-_28477023 0.21 ENSDART00000137008
bobby sox homolog (Drosophila)
chr3_+_2669813 0.21 ENSDART00000014205

chr14_-_28001986 0.20 ENSDART00000054115
TSC22 domain family, member 3
chr19_+_30990815 0.20 ENSDART00000134645
syncoilin, intermediate filament protein
chr16_+_43152727 0.20 ENSDART00000125590
ENSDART00000154493
ADAM metallopeptidase domain 22
chr11_-_45216684 0.19 ENSDART00000168621
transmembrane channel-like 8
chr19_+_41464870 0.19 ENSDART00000102778
distal-less homeobox 6a

Network of associatons between targets according to the STRING database.

First level regulatory network of pou3f1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.5 4.5 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.5 2.0 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.4 1.5 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.3 4.1 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.3 1.8 GO:0099525 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.3 0.8 GO:0035992 tendon formation(GO:0035992)
0.2 0.9 GO:0007638 mechanosensory behavior(GO:0007638)
0.2 0.7 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.2 1.0 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.2 1.0 GO:0046677 response to antibiotic(GO:0046677)
0.2 1.4 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.2 1.9 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.2 0.7 GO:0016038 absorption of visible light(GO:0016038)
0.2 0.5 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.1 0.3 GO:1904861 excitatory synapse assembly(GO:1904861)
0.1 1.7 GO:0042044 fluid transport(GO:0042044)
0.1 0.7 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 1.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.5 GO:0060074 synapse maturation(GO:0060074)
0.1 1.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 1.7 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 1.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 1.1 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 0.5 GO:0070572 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.1 1.3 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.1 0.7 GO:0071305 vitamin D3 metabolic process(GO:0070640) cellular response to vitamin D(GO:0071305)
0.1 1.0 GO:0071941 nitrogen cycle metabolic process(GO:0071941)
0.1 1.2 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 2.9 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 0.5 GO:0019370 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.1 1.5 GO:0036065 fucosylation(GO:0036065)
0.1 0.3 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.1 2.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.6 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.1 0.6 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 3.0 GO:0016126 sterol biosynthetic process(GO:0016126)
0.1 1.6 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 1.0 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.1 0.6 GO:0050975 sensory perception of touch(GO:0050975)
0.1 1.3 GO:0006825 copper ion transport(GO:0006825)
0.1 1.0 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 0.8 GO:0030819 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.1 0.3 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.1 0.6 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.6 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.2 GO:0033119 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.5 GO:0048796 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.0 1.4 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 1.1 GO:0008272 sulfate transport(GO:0008272)
0.0 0.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 1.0 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.5 GO:0033344 cholesterol efflux(GO:0033344)
0.0 1.7 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.5 GO:0090559 intestinal absorption(GO:0050892) regulation of membrane permeability(GO:0090559)
0.0 0.4 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.6 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 1.6 GO:0007602 phototransduction(GO:0007602)
0.0 0.9 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 0.5 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.8 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.3 GO:0046850 regulation of bone remodeling(GO:0046850)
0.0 0.5 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 1.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 2.8 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.3 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0 0.4 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 1.5 GO:0008217 regulation of blood pressure(GO:0008217)
0.0 0.5 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0050654 chondroitin sulfate proteoglycan metabolic process(GO:0050654)
0.0 0.4 GO:0071218 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.0 0.7 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.1 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.0 0.1 GO:0051932 regulation of synaptic transmission, GABAergic(GO:0032228) synaptic transmission, GABAergic(GO:0051932)
0.0 0.1 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.0 0.6 GO:0043534 blood vessel endothelial cell migration(GO:0043534)
0.0 0.2 GO:0035141 medial fin morphogenesis(GO:0035141)
0.0 0.1 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 1.1 GO:0006352 DNA-templated transcription, initiation(GO:0006352)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.1 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.3 1.0 GO:0097524 sperm plasma membrane(GO:0097524)
0.2 3.8 GO:0043195 terminal bouton(GO:0043195)
0.1 2.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 1.0 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.9 GO:0061617 MICOS complex(GO:0061617)
0.1 1.8 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.8 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.6 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 1.9 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 1.1 GO:0005844 polysome(GO:0005844)
0.0 0.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 1.3 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 2.3 GO:0042383 sarcolemma(GO:0042383)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 4.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0016234 inclusion body(GO:0016234)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.4 GO:0043025 neuronal cell body(GO:0043025)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.4 1.2 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.3 1.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.3 1.3 GO:0016531 copper chaperone activity(GO:0016531)
0.2 3.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 0.7 GO:0005502 11-cis retinal binding(GO:0005502)
0.2 1.0 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 1.0 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 1.4 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.2 1.2 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.2 2.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.2 1.0 GO:0008126 acetylesterase activity(GO:0008126)
0.2 1.1 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.1 1.0 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 0.7 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 0.5 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 1.3 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.1 1.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.5 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 1.5 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 0.9 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 1.1 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 1.5 GO:0016854 racemase and epimerase activity(GO:0016854)
0.1 1.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 1.7 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 2.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 1.1 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.6 GO:0051117 ATPase binding(GO:0051117)
0.0 1.2 GO:0008483 transaminase activity(GO:0008483)
0.0 2.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 2.4 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.4 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 1.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.7 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.5 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 2.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.4 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0001729 ceramide kinase activity(GO:0001729)
0.0 0.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.3 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 1.9 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 2.7 GO:0005179 hormone activity(GO:0005179)
0.0 3.1 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.3 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.4 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 2.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 1.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.6 GO:0044325 ion channel binding(GO:0044325)
0.0 0.4 GO:0035064 methylated histone binding(GO:0035064)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 2.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.5 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.5 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME OPSINS Genes involved in Opsins
0.1 1.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.3 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 0.3 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.7 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 1.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.5 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases