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PRJEB1986: zebrafish developmental stages transcriptome

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Results for pou2f2a

Z-value: 1.07

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Transcription factors associated with pou2f2a

Gene Symbol Gene ID Gene Info
ENSDARG00000019658 POU class 2 homeobox 2a
ENSDARG00000036816 POU class 2 homeobox 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou2f2adr11_v1_chr16_+_10918252_10918252-0.662.1e-03Click!

Activity profile of pou2f2a motif

Sorted Z-values of pou2f2a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_6081803 4.78 ENSDART00000099224
deltaD
chr23_+_21473103 4.67 ENSDART00000142921
si:ch73-21g5.7
chr25_+_22320738 3.56 ENSDART00000073566
cytochrome P450, family 11, subfamily A, polypeptide 1
chr4_+_15968483 3.33 ENSDART00000101575
si:dkey-117n7.5
chr14_-_32965169 3.07 ENSDART00000114973
caudal type homeobox 4
chr11_-_11575070 2.62 ENSDART00000142208
zgc:110712
chr14_-_26704829 2.38 ENSDART00000078563
neurogenin 1
chr5_-_66028371 2.28 ENSDART00000183012
NOTCH regulated ankyrin repeat protein b
chr7_+_15736230 2.11 ENSDART00000109942
multiple C2 domains, transmembrane 2b
chr23_+_7692042 2.05 ENSDART00000018512
protein O-fucosyltransferase 1
chr23_+_12454542 2.04 ENSDART00000182259
ENSDART00000193043
si:ch211-153a8.4
chr5_-_66028714 1.87 ENSDART00000022625
ENSDART00000164228
NOTCH regulated ankyrin repeat protein b
chr17_-_4245311 1.84 ENSDART00000055379
growth differentiation factor 3
chr15_+_7187228 1.75 ENSDART00000109394
hairy-related 13
chr20_+_48782068 1.71 ENSDART00000159275
NK2 homeobox 2b
chr1_+_54013457 1.67 ENSDART00000012104
ENSDART00000126339
deltaA
chr1_-_51720633 1.59 ENSDART00000045894
ribonuclease H2, subunit A
chr21_-_34926619 1.56 ENSDART00000065337
ENSDART00000192740
kinesin family member 20A
chr21_-_44512893 1.54 ENSDART00000166853
zgc:136410
chr22_+_35930526 1.54 ENSDART00000169242

chr19_+_19775757 1.51 ENSDART00000164677
homeobox A3a
chr23_+_23232136 1.47 ENSDART00000126479
ENSDART00000187764
pleckstrin homology domain containing, family N member 1
chr14_+_35383267 1.46 ENSDART00000143818
clathrin interactor 1a
chr4_-_9780931 1.44 ENSDART00000134280
ENSDART00000150664
ENSDART00000150304
ENSDART00000080744
SVOP-like
chr19_-_41518922 1.41 ENSDART00000164483
ENSDART00000062080
chromatin accessibility complex 1
chr5_-_65662996 1.40 ENSDART00000147707
calmodulin regulated spectrin-associated protein 1b
chr11_-_30158609 1.36 ENSDART00000006669
Scm polycomb group protein like 2
chr17_+_23311377 1.35 ENSDART00000128073
protein phosphatase 1, regulatory subunit 3Ca
chr10_+_10351685 1.33 ENSDART00000109432
cerebral endothelial cell adhesion molecule
chr8_+_28593707 1.33 ENSDART00000097213
transcription factor 15
chr10_-_7555326 1.32 ENSDART00000162191
ENSDART00000186945
Werner syndrome
chr13_-_30996072 1.32 ENSDART00000181661
WDFY family member 4
chr3_-_5964557 1.31 ENSDART00000184738

chr2_+_4146606 1.31 ENSDART00000171170
mindbomb E3 ubiquitin protein ligase 1
chr19_+_9459050 1.29 ENSDART00000186419
si:ch211-288g17.3
chr12_+_16087077 1.28 ENSDART00000141898
zinc finger protein 281b
chr4_-_64141714 1.28 ENSDART00000128628

chr2_+_4146299 1.27 ENSDART00000173418
mindbomb E3 ubiquitin protein ligase 1
chr19_-_18152942 1.23 ENSDART00000190182
nuclear factor, erythroid 2-like 3
chr14_-_38929885 1.20 ENSDART00000148737
Bruton agammaglobulinemia tyrosine kinase
chr7_-_32020858 1.20 ENSDART00000023568
kinesin family member 18A
chr1_+_24557414 1.19 ENSDART00000076519
dCTP pyrophosphatase 1
chr7_+_20917966 1.18 ENSDART00000129161
WD repeat containing, antisense to TP53
chr10_-_1961930 1.17 ENSDART00000122446
teratocarcinoma-derived growth factor 1
chr23_-_1017428 1.17 ENSDART00000110588
ENSDART00000183158
cadherin 26, tandem duplicate 1
chr9_+_29431763 1.17 ENSDART00000186095
ENSDART00000182640
UDP-glucose glycoprotein glucosyltransferase 2
chr20_+_53441935 1.17 ENSDART00000175214
apolipoprotein Bb, tandem duplicate 2
chr11_+_25010491 1.16 ENSDART00000167285
zgc:92107
chr4_+_58695514 1.14 ENSDART00000169840
si:dkey-25i10.1
chr1_-_46832880 1.13 ENSDART00000142406
si:ch73-160h15.3
chr7_-_41512999 1.13 ENSDART00000173577
si:dkey-10f23.2
chr4_+_29206813 1.13 ENSDART00000131893
si:dkey-23a23.1
chr23_-_1017605 1.12 ENSDART00000138290
cadherin 26, tandem duplicate 1
chr17_-_4245902 1.12 ENSDART00000151851
growth differentiation factor 3
chr6_-_9581949 1.12 ENSDART00000144335
cytochrome P450, family 27, subfamily C, polypeptide 1
chr16_+_25074029 1.11 ENSDART00000155465
si:dkeyp-84f3.9
chr4_+_9592486 1.11 ENSDART00000080829
heat shock protein 14
chr16_+_38167883 1.10 ENSDART00000111796
phosphatidylinositol 4-kinase, catalytic, beta
chr12_+_23424108 1.10 ENSDART00000077732
BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a
chr5_-_63302944 1.10 ENSDART00000047110
gelsolin b
chr7_-_57637779 1.10 ENSDART00000028017
MAD2 mitotic arrest deficient-like 1 (yeast)
chr24_-_23758003 1.10 ENSDART00000178085
Danio rerio minichromosome maintenance domain containing 2 (mcmdc2), mRNA.
chr9_-_27398369 1.09 ENSDART00000186499
testis expressed 30
chr4_+_64549970 1.07 ENSDART00000167846
si:ch211-223a21.3
chr3_-_27646070 1.06 ENSDART00000122031
ENSDART00000151027
si:ch211-157c3.4
chr18_+_22174630 1.05 ENSDART00000089549
RHO family interacting cell polarization regulator 1
chr12_+_27096835 1.05 ENSDART00000149475
tubulin tyrosine ligase-like family, member 6
chr16_-_21912210 1.04 ENSDART00000165824
SET domain, bifurcated 1b
chr9_-_53666031 1.04 ENSDART00000126314
protocadherin 8
chr19_-_18152407 1.04 ENSDART00000193264
ENSDART00000016135
nuclear factor, erythroid 2-like 3
chr24_-_31904924 1.02 ENSDART00000156060
ENSDART00000129741
ENSDART00000154276
si:ch73-78o10.1
chr16_-_21620947 1.02 ENSDART00000115011
ENSDART00000183125
ENSDART00000188856
ENSDART00000189460
discoidin domain receptor tyrosine kinase 1
chr16_-_31790285 1.01 ENSDART00000184655
chromodomain helicase DNA binding protein 4b
chr1_-_25438737 1.01 ENSDART00000134470
FH2 domain containing 1
chr5_+_63302660 0.99 ENSDART00000142131
si:ch73-376l24.2
chr21_+_20903244 0.98 ENSDART00000186193
complement component 7b
chr7_-_8315179 0.95 ENSDART00000184049
coagulation factor XIII, A1 polypeptide b
chr5_+_45322734 0.94 ENSDART00000084411
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr3_-_26806032 0.94 ENSDART00000143710
phosphatidylinositol glycan anchor biosynthesis, class Q
chr12_-_35582683 0.93 ENSDART00000167933
SEC24 homolog C, COPII coat complex component
chr13_+_48617974 0.92 ENSDART00000168596
si:ch1073-268j14.1
chr15_-_29388012 0.92 ENSDART00000115032
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b
chr2_-_22993601 0.91 ENSDART00000125049
ENSDART00000099735
MLLT1, super elongation complex subunit b
chr7_-_12065668 0.90 ENSDART00000101537
mex-3 RNA binding family member B
chr5_+_9259971 0.89 ENSDART00000163060
sushi domain containing 1
chr17_+_26965351 0.89 ENSDART00000114215
ENSDART00000147192
grainyhead-like transcription factor 3
chr23_+_16864130 0.89 ENSDART00000060181
zgc:114174
chr24_+_37825634 0.88 ENSDART00000129889
intraflagellar transport 140 homolog (Chlamydomonas)
chr18_+_30998472 0.87 ENSDART00000154993
ENSDART00000099333
CD151 antigen, like
chr8_+_36570508 0.87 ENSDART00000145868
polymerase (DNA directed), delta 2, regulatory subunit
chr20_+_25625872 0.87 ENSDART00000078385
phosphoribosyl pyrophosphate amidotransferase
chr23_-_20126257 0.87 ENSDART00000005021
transketolase b
chr22_+_5135884 0.86 ENSDART00000141276
myeloid-derived growth factor
chr21_+_19070921 0.84 ENSDART00000029874
NK6 homeobox 1
chr18_+_6866276 0.84 ENSDART00000187516
DnaJ (Hsp40) homolog, subfamily A, member 2, like
chr18_+_34667486 0.84 ENSDART00000163583

chr4_-_73351733 0.84 ENSDART00000169597
si:cabz01021426.2
chr23_+_12455295 0.83 ENSDART00000143752
ENSDART00000135785
si:ch211-153a8.4
chr17_-_31579715 0.83 ENSDART00000110167
ENSDART00000191092
RNA polymerase II associated protein 1
chr10_-_1961576 0.82 ENSDART00000042441
teratocarcinoma-derived growth factor 1
chr2_+_56213694 0.82 ENSDART00000162582
upf1 regulator of nonsense transcripts homolog (yeast)
chr3_-_33422738 0.82 ENSDART00000075493
coiled-coil domain containing 103
chr22_-_17611742 0.81 ENSDART00000144031
glutathione peroxidase 4a
chr22_+_2111820 0.81 ENSDART00000135500
zinc finger protein 1144
chr13_-_10431476 0.81 ENSDART00000133968
calmodulin-lysine N-methyltransferase
chr15_-_16012963 0.81 ENSDART00000144138
HNF1 homeobox Ba
chr25_+_5288665 0.80 ENSDART00000169540

chr1_-_25438934 0.79 ENSDART00000111686
FH2 domain containing 1
chr10_-_74408 0.79 ENSDART00000100073
ENSDART00000141723
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, a
chr4_+_23126558 0.78 ENSDART00000162859
MDM2 oncogene, E3 ubiquitin protein ligase
chr19_+_20178978 0.78 ENSDART00000145115
ENSDART00000151175
transformer 2 alpha homolog
chr6_-_40286633 0.77 ENSDART00000033844
collagen, type VII, alpha 1
chr5_-_25072607 0.77 ENSDART00000145061
patatin-like phospholipase domain containing 7b
chr9_+_22634073 0.76 ENSDART00000181822
ets variant 5a
chr12_-_34887943 0.76 ENSDART00000027379
BRD4 interacting chromatin remodeling complex associated protein like
chr4_+_47656992 0.75 ENSDART00000161148
zinc finger protein 1040
chr4_+_59362813 0.75 ENSDART00000150655
zinc finger protein 1050
chr2_-_38206331 0.74 ENSDART00000136082
apoptotic chromatin condensation inducer 1a
chr21_-_2185600 0.74 ENSDART00000169897
zgc:171220
chr21_+_26522571 0.71 ENSDART00000134617
adenylosuccinate synthase, like
chr8_-_39654669 0.71 ENSDART00000145677
si:dkey-63d15.12
chr22_+_2364835 0.70 ENSDART00000174974
si:dkey-4c15.13
chr20_-_22476255 0.69 ENSDART00000103510
platelet-derived growth factor receptor, alpha polypeptide
chr15_-_29387446 0.69 ENSDART00000145976
ENSDART00000035096
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b
chr10_+_3145707 0.68 ENSDART00000160046
hypermethylated in cancer 2
chr9_-_30502010 0.68 ENSDART00000149483
si:dkey-229b18.3
chr11_+_19433936 0.68 ENSDART00000162081
prickle homolog 2b
chr17_+_24722646 0.68 ENSDART00000138356
mitochondrial fission regulator 1-like
chr16_-_25380903 0.67 ENSDART00000086375
ENSDART00000188587
ADNP homeobox 2a
chr11_-_35575791 0.67 ENSDART00000031441
ENSDART00000188513
ENSDART00000183609
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb
chr1_-_51038885 0.67 ENSDART00000035150
spastin
chr6_-_54111928 0.67 ENSDART00000083880
hyaluronoglucosaminidase 2a
chr6_+_41446541 0.66 ENSDART00000029553
ENSDART00000128756
ENSDART00000144864
REM2 and RAB-like small GTPase 1
chr15_-_34658057 0.66 ENSDART00000110964
BCL2 associated athanogene 6
chr8_+_7315625 0.66 ENSDART00000135655
ENSDART00000181048
selenoprotein H
chr1_-_55166511 0.65 ENSDART00000150430
ENSDART00000035725
proliferation associated nuclear element
chr5_+_33287611 0.65 ENSDART00000125093
ENSDART00000146759
mediator complex subunit 22
chr5_+_29726428 0.65 ENSDART00000143183
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr7_-_51461649 0.65 ENSDART00000193947
ENSDART00000174328
Rho GTPase activating protein 36
chr2_-_7185460 0.65 ENSDART00000092078
ring finger and CCCH-type domains 1b
chr5_+_38837429 0.65 ENSDART00000160236
Fraser extracellular matrix complex subunit 1
chr4_-_48636872 0.64 ENSDART00000168605
zinc finger protein 1063
chr5_+_59494079 0.64 ENSDART00000148727
GTF2I repeat domain containing 1
chr4_+_32649955 0.64 ENSDART00000135750
zinc finger protein 1042
chr8_+_36570791 0.64 ENSDART00000145566
ENSDART00000180527
polymerase (DNA directed), delta 2, regulatory subunit
chr12_+_4160804 0.63 ENSDART00000152515
integrin, alpha M (complement component 3 receptor 3 subunit)
chr24_+_35827766 0.63 ENSDART00000144700
si:dkeyp-7a3.1
chr15_-_18574716 0.63 ENSDART00000142010
ENSDART00000019006
neural cell adhesion molecule 1b
chr21_-_2185004 0.63 ENSDART00000163405
zgc:171220
chr15_-_25083200 0.63 ENSDART00000156053
Pim proto-oncogene, serine/threonine kinase, related 191
chr19_-_21716593 0.62 ENSDART00000155126
zinc finger protein 516
chr14_+_35428152 0.61 ENSDART00000172597
synaptotagmin-like 4
chr19_+_3140313 0.61 ENSDART00000125504
zgc:86598
chr4_-_56157199 0.60 ENSDART00000169806
si:ch211-207e19.15
chr4_-_45337903 0.60 ENSDART00000159767
si:dkey-247i3.6
chr6_+_56147812 0.60 ENSDART00000150219
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr3_-_15119856 0.60 ENSDART00000138328
exportin 6
chr20_+_25626479 0.60 ENSDART00000143883
phosphoribosyl pyrophosphate amidotransferase
chr3_+_24275766 0.60 ENSDART00000055607
platelet-derived growth factor beta polypeptide b
chr22_+_13917311 0.60 ENSDART00000022654
SH3-domain binding protein 4a
chr5_-_68782641 0.59 ENSDART00000141699
methylphosphate capping enzyme
chr4_-_35989745 0.59 ENSDART00000162568
zinc finger protein 1125
chr4_-_5831522 0.59 ENSDART00000008898
forkhead box M1
chr21_-_32467099 0.59 ENSDART00000186354
zgc:123105
chr6_-_22146258 0.58 ENSDART00000181700
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr11_+_18612421 0.58 ENSDART00000110621
nuclear receptor coactivator 3
chr3_-_58165254 0.57 ENSDART00000093031
SNU13 homolog, small nuclear ribonucleoprotein a (U4/U6.U5)
chr24_+_29912509 0.57 ENSDART00000168422
ferric-chelate reductase 1b
chr1_+_31725154 0.57 ENSDART00000112333
ENSDART00000189801
cyclin and CBS domain divalent metal cation transport mediator 2b
chr3_+_28581397 0.57 ENSDART00000150893
septin 12
chr19_+_3653976 0.56 ENSDART00000125673
neural precursor cell expressed, developmentally down-regulated 9
chr4_-_50434519 0.56 ENSDART00000150372
zinc finger protein 1061
chr23_+_2825940 0.56 ENSDART00000135781
phospholipase C, gamma 1
chr22_+_5135193 0.56 ENSDART00000106156
myeloid-derived growth factor
chr1_-_54100988 0.55 ENSDART00000192662
regulatory factor X, 1b (influences HLA class II expression)
chr13_-_40411908 0.55 ENSDART00000057094
ENSDART00000150091
NK2 homeobox 3
chr19_+_19759577 0.55 ENSDART00000169480
homeobox A5a
chr11_+_18612166 0.55 ENSDART00000162694
nuclear receptor coactivator 3
chr11_-_30158191 0.54 ENSDART00000155278
ENSDART00000156121
Scm polycomb group protein like 2
chr4_-_52621232 0.54 ENSDART00000124451
si:dkeyp-104f11.6
chr18_-_14734678 0.54 ENSDART00000142462
teashirt zinc finger homeobox 3a
chr4_+_18489207 0.53 ENSDART00000135276
si:dkey-202b22.5
chr5_+_26212621 0.53 ENSDART00000134432
occludin b
chr22_-_10397600 0.53 ENSDART00000181964
ENSDART00000142886
nischarin
chr14_-_40389699 0.52 ENSDART00000181581
ENSDART00000173398
protocadherin 19
chr1_+_7679328 0.52 ENSDART00000163488
ENSDART00000190070
engrailed homeobox 1b
chr8_-_24803111 0.52 ENSDART00000186281

chr4_+_31259 0.52 ENSDART00000166826
putative homeodomain transcription factor 2
chr12_-_33579873 0.52 ENSDART00000184661
tudor and KH domain containing
chr7_+_36041509 0.50 ENSDART00000162850
iroquois homeobox 3a
chr4_+_33420247 0.50 ENSDART00000150868
zinc finger protein 1065
chr20_+_27464721 0.50 ENSDART00000189552
kinesin family member 26Aa
chr4_+_50726871 0.49 ENSDART00000150469
zinc finger protein 1058
chr2_-_17393971 0.49 ENSDART00000100201
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr19_+_9232676 0.49 ENSDART00000136957
lysine (K)-specific methyltransferase 2Ba
chr20_-_25626693 0.48 ENSDART00000132247
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr4_-_67712607 0.48 ENSDART00000162955
zinc finger protein 1091
chr21_-_41070182 0.48 ENSDART00000026064
leucyl-tRNA synthetase b
chr6_+_33885828 0.48 ENSDART00000179994
GC-rich promoter binding protein 1-like 1
chr19_+_43256986 0.47 ENSDART00000182336
diacylglycerol kinase delta

Network of associatons between targets according to the STRING database.

First level regulatory network of pou2f2a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0007440 foregut morphogenesis(GO:0007440)
1.0 5.0 GO:0021516 dorsal spinal cord development(GO:0021516)
0.7 3.6 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.7 4.8 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.7 0.7 GO:0031112 positive regulation of microtubule polymerization or depolymerization(GO:0031112)
0.7 2.0 GO:0090008 hypoblast development(GO:0090008)
0.6 3.0 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.4 1.7 GO:0055016 hypochord development(GO:0055016)
0.4 1.2 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.4 1.5 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.3 2.0 GO:0006004 fucose metabolic process(GO:0006004)
0.3 1.3 GO:0044806 multicellular organism aging(GO:0010259) G-quadruplex DNA unwinding(GO:0044806)
0.3 0.6 GO:0035477 regulation of angioblast cell migration involved in selective angioblast sprouting(GO:0035477)
0.3 0.8 GO:0036159 inner dynein arm assembly(GO:0036159)
0.3 1.6 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.3 1.8 GO:0060017 parathyroid gland development(GO:0060017)
0.2 1.2 GO:0030576 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.2 1.4 GO:0031113 regulation of microtubule polymerization(GO:0031113)
0.2 1.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.2 2.7 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.2 0.6 GO:1903392 epicardial cell to mesenchymal cell transition(GO:0003347) negative regulation of adherens junction organization(GO:1903392)
0.2 0.6 GO:1904871 positive regulation of protein localization to nucleus(GO:1900182) protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.2 2.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.2 0.8 GO:0048566 embryonic digestive tract development(GO:0048566)
0.2 0.5 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.2 0.5 GO:0045649 regulation of macrophage differentiation(GO:0045649)
0.2 0.8 GO:1904036 negative regulation of epithelial cell apoptotic process(GO:1904036)
0.1 0.6 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 1.7 GO:0033505 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.1 0.4 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.7 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.1 0.4 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.1 0.4 GO:0061178 insulin secretion involved in cellular response to glucose stimulus(GO:0035773) regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.1 0.4 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 0.6 GO:0090527 actin filament reorganization(GO:0090527)
0.1 1.4 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 0.4 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 1.4 GO:0031937 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 1.5 GO:0045682 regulation of epidermis development(GO:0045682)
0.1 1.5 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.1 0.2 GO:0061323 cell proliferation involved in heart morphogenesis(GO:0061323) regulation of cell proliferation involved in heart morphogenesis(GO:2000136)
0.1 0.5 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.1 0.7 GO:0006167 AMP biosynthetic process(GO:0006167)
0.1 1.4 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.1 1.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.9 GO:0006611 protein export from nucleus(GO:0006611)
0.1 0.9 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 0.5 GO:0021767 mammillary body development(GO:0021767)
0.1 1.0 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.1 0.3 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 1.1 GO:0042026 protein refolding(GO:0042026)
0.1 1.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.1 1.0 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.1 0.7 GO:0021794 thalamus development(GO:0021794)
0.1 0.8 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 0.3 GO:0071869 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.1 1.0 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.6 GO:0071156 regulation of cell cycle arrest(GO:0071156)
0.1 0.8 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.1 0.4 GO:0070650 actin filament bundle distribution(GO:0070650)
0.1 0.4 GO:0003348 cardiac endothelial cell differentiation(GO:0003348) endocardial cell differentiation(GO:0060956)
0.1 0.4 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 1.3 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.1 0.4 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.2 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 1.0 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 1.1 GO:0030168 platelet activation(GO:0030168)
0.1 0.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.7 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 1.1 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.0 0.2 GO:1904086 regulation of epiboly involved in gastrulation with mouth forming second(GO:1904086)
0.0 0.4 GO:0031179 peptide modification(GO:0031179)
0.0 2.3 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.8 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 3.2 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.9 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.0 1.3 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.0 1.0 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 1.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.3 GO:0090050 positive regulation of blood vessel endothelial cell migration(GO:0043536) positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 1.1 GO:0060872 semicircular canal development(GO:0060872)
0.0 1.3 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.2 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.3 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.9 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.5 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 1.6 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 1.6 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.3 GO:0010885 regulation of cholesterol storage(GO:0010885)
0.0 0.8 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 1.2 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.5 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.2 GO:0090594 inflammatory response to wounding(GO:0090594)
0.0 1.2 GO:0002250 adaptive immune response(GO:0002250)
0.0 0.1 GO:0042823 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.0 0.7 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.3 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.7 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.4 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.2 GO:0010002 cardioblast differentiation(GO:0010002)
0.0 0.2 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.6 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.3 GO:0016203 muscle attachment(GO:0016203)
0.0 0.2 GO:0043490 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.6 GO:0042129 regulation of T cell proliferation(GO:0042129)
0.0 0.4 GO:0008345 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.0 0.1 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0 0.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.7 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.1 GO:0090113 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.0 0.5 GO:0048663 neuron fate commitment(GO:0048663)
0.0 0.1 GO:0046958 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 0.3 GO:0060030 dorsal convergence(GO:0060030)
0.0 0.6 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.1 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.2 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.6 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.0 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:0031268 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0090398 cellular senescence(GO:0090398)
0.0 0.5 GO:0001841 neural tube formation(GO:0001841)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 GO:0005880 nuclear microtubule(GO:0005880)
0.4 1.6 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.4 1.6 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.3 1.5 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.2 1.2 GO:0034359 mature chylomicron(GO:0034359)
0.2 0.9 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 1.4 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.5 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.9 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 1.3 GO:0031010 ISWI-type complex(GO:0031010)
0.1 0.6 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.7 GO:0071818 BAT3 complex(GO:0071818)
0.1 2.0 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 1.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.2 GO:0015030 Cajal body(GO:0015030)
0.1 0.8 GO:0036157 outer dynein arm(GO:0036157)
0.1 1.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.0 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.6 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.2 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.3 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 8.1 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 2.3 GO:0016342 catenin complex(GO:0016342)
0.0 0.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 1.5 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.3 GO:0042627 chylomicron(GO:0042627)
0.0 0.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.8 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.3 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.4 GO:0044447 axoneme part(GO:0044447)
0.0 0.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.0 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0017177 glucosidase II complex(GO:0017177)
0.0 1.3 GO:0005871 kinesin complex(GO:0005871)
0.0 1.0 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.6 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 1.8 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 1.2 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.5 1.5 GO:1901612 cardiolipin binding(GO:1901612)
0.3 2.4 GO:0070888 E-box binding(GO:0070888)
0.3 1.3 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.2 1.2 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.2 1.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2 5.3 GO:0005112 Notch binding(GO:0005112)
0.2 1.2 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.2 0.7 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.2 0.7 GO:0048487 beta-tubulin binding(GO:0048487)
0.2 0.7 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.2 0.8 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.2 1.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.2 1.4 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.2 2.0 GO:0070697 activin receptor binding(GO:0070697)
0.1 1.3 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 0.9 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.1 1.1 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.4 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.9 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 1.2 GO:0070325 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
0.1 1.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.5 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 1.0 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.1 0.3 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
0.1 0.3 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 1.7 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 0.6 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 1.3 GO:2001069 glycogen binding(GO:2001069)
0.1 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 1.0 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.1 0.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 1.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.5 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.1 1.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.6 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.3 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.4 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 1.6 GO:0005518 collagen binding(GO:0005518)
0.1 0.9 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 1.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.7 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.7 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.4 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 1.5 GO:0005109 frizzled binding(GO:0005109)
0.0 4.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.0 0.2 GO:0005113 patched binding(GO:0005113)
0.0 0.7 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.4 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.0 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 4.2 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 2.1 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.3 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 6.9 GO:0003682 chromatin binding(GO:0003682)
0.0 0.7 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 1.5 GO:0003724 RNA helicase activity(GO:0003724)
0.0 1.5 GO:0051536 iron-sulfur cluster binding(GO:0051536) metal cluster binding(GO:0051540)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 1.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.4 GO:0016411 acylglycerol O-acyltransferase activity(GO:0016411)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 35.7 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 0.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.6 GO:0045296 cadherin binding(GO:0045296)
0.0 0.8 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0048038 quinone binding(GO:0048038)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.7 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.9 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 2.6 GO:0042802 identical protein binding(GO:0042802)
0.0 2.0 GO:0005125 cytokine activity(GO:0005125)
0.0 0.3 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.0 2.8 GO:0008017 microtubule binding(GO:0008017)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.2 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.8 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 1.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 1.8 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 1.2 ST GA12 PATHWAY G alpha 12 Pathway
0.1 0.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 5.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 0.8 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 2.6 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.6 PID AURORA B PATHWAY Aurora B signaling
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.7 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.6 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.5 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.6 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.4 3.6 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.2 2.0 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 2.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 0.6 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 1.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 2.4 REACTOME KINESINS Genes involved in Kinesins
0.1 2.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 1.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.0 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 0.9 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.2 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 2.0 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.8 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.1 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 1.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.5 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.2 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation