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PRJEB1986: zebrafish developmental stages transcriptome

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Results for pou1f1

Z-value: 0.34

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Transcription factors associated with pou1f1

Gene Symbol Gene ID Gene Info
ENSDARG00000058924 POU class 1 homeobox 1
ENSDARG00000110816 POU class 1 homeobox 1
ENSDARG00000115109 POU class 1 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou1f1dr11_v1_chr9_-_19161982_191619820.126.3e-01Click!

Activity profile of pou1f1 motif

Sorted Z-values of pou1f1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_22099536 2.86 ENSDART00000101923

chr12_-_17712393 2.01 ENSDART00000143534
ENSDART00000010144
parvalbumin 2
chr9_-_22213297 1.67 ENSDART00000110656
ENSDART00000133149
crystallin, gamma M2d20
chr14_+_46313396 1.05 ENSDART00000047525
crystallin, beta A1, like 1
chr21_-_20939488 1.03 ENSDART00000039043
regulator of G protein signaling 7 binding protein b
chr25_+_31227747 0.86 ENSDART00000033872
troponin I type 2a (skeletal, fast), tandem duplicate 1
chr5_-_44829719 0.81 ENSDART00000019104
fructose-1,6-bisphosphatase 2
chr2_+_2223837 0.79 ENSDART00000101038
ENSDART00000129354
transmembrane inner ear
chr9_+_18716485 0.77 ENSDART00000135125
stress-associated endoplasmic reticulum protein family member 2
chr4_+_9669717 0.77 ENSDART00000004604
si:dkey-153k10.9
chr20_-_40755614 0.64 ENSDART00000061247
connexin 32.3
chr16_-_28856112 0.64 ENSDART00000078543
synaptotagmin XIb
chr16_-_12173554 0.59 ENSDART00000110567
ENSDART00000155935
calsyntenin 3
chr9_+_54290896 0.57 ENSDART00000149175
POU class 4 homeobox 3
chr23_+_31405497 0.55 ENSDART00000053546
SH3 domain binding glutamate-rich protein like 2
chr4_-_5302866 0.52 ENSDART00000138590
si:ch211-214j24.9
chr9_+_34641237 0.50 ENSDART00000133996
short stature homeobox
chr20_-_5291012 0.50 ENSDART00000122892
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 3
chr9_+_2574122 0.50 ENSDART00000166326
ENSDART00000191822
si:ch73-167c12.2
chr13_-_29420885 0.49 ENSDART00000024225
choline O-acetyltransferase a
chr23_-_20051369 0.49 ENSDART00000049836
biglycan b
chr5_-_41494831 0.49 ENSDART00000051081
eukaryotic translation elongation factor 2, like 2
chr7_+_24573721 0.47 ENSDART00000173938
ENSDART00000173681
si:dkeyp-75h12.7
chr6_+_39905021 0.47 ENSDART00000064904
endonuclease, polyU-specific
chr5_-_71705191 0.47 ENSDART00000187767
adenylate kinase 1
chr16_+_46111849 0.47 ENSDART00000172232
synaptic vesicle glycoprotein 2A
chr19_+_10339538 0.47 ENSDART00000151808
ENSDART00000151235
recoverin 3
chr8_-_33114202 0.44 ENSDART00000098840
Ral GEF with PH domain and SH3 binding motif 1
chr3_+_23092762 0.43 ENSDART00000142884
ENSDART00000024136
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a
chr19_-_26869103 0.43 ENSDART00000089699
proline-rich transmembrane protein 1
chr18_+_924949 0.43 ENSDART00000170888
ENSDART00000193163
pyruvate kinase M1/2a
chr7_-_66868543 0.43 ENSDART00000149680
adenosine monophosphate deaminase 3a
chr11_+_30663300 0.40 ENSDART00000161662
tau tubulin kinase 1a
chr1_-_22757145 0.40 ENSDART00000134719
prominin 1 b
chr15_-_46779934 0.40 ENSDART00000085136
chloride channel 2c
chr6_-_11768198 0.40 ENSDART00000183463
membrane-associated ring finger (C3HC4) 7
chr18_+_39487486 0.39 ENSDART00000126978
acyl-CoA dehydrogenase long chain
chr5_+_2815021 0.39 ENSDART00000020472
4-hydroxyphenylpyruvate dioxygenase a
chr7_+_73397283 0.39 ENSDART00000174390

chr6_-_28980756 0.38 ENSDART00000014661
glomulin, FKBP associated protein b
chr16_-_22781446 0.37 ENSDART00000144107
lens epithelial protein
chr3_-_48716422 0.36 ENSDART00000164979
si:ch211-114m9.1
chr21_-_22635245 0.36 ENSDART00000115224
ENSDART00000101782
nectin cell adhesion molecule 1a
chr13_+_24279021 0.36 ENSDART00000058629
actin, alpha 1b, skeletal muscle
chr16_-_28658341 0.35 ENSDART00000148456
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr17_-_12336987 0.34 ENSDART00000172001
synaptosomal-associated protein, 25b
chr20_-_44557037 0.33 ENSDART00000140995
major facilitator superfamily domain containing 2B
chr11_+_30057762 0.33 ENSDART00000164139
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr2_-_7666021 0.33 ENSDART00000180007

chr1_-_22512063 0.32 ENSDART00000031546
ENSDART00000190987
cholinergic receptor, nicotinic, alpha 6
chr25_-_4146947 0.32 ENSDART00000129268
fatty acid desaturase 2
chr1_-_15797663 0.32 ENSDART00000177122
sarcoglycan zeta
chr25_+_14087045 0.32 ENSDART00000155770
actin, alpha, cardiac muscle 1c
chr22_-_13851297 0.31 ENSDART00000080306
S100 calcium binding protein, beta (neural)
chr20_-_34750363 0.31 ENSDART00000152845
zinc finger protein 395b
chr11_-_29737088 0.30 ENSDART00000159828
si:ch211-218g23.6
chr8_+_7359294 0.30 ENSDART00000121708
proprotein convertase subtilisin/kexin type 1 inhibitor, like
chr16_+_9540033 0.30 ENSDART00000149574
carbonic anhydrase XIV
chr4_+_22480169 0.30 ENSDART00000146272
ENSDART00000066904
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr19_+_43297546 0.30 ENSDART00000168002
lysosomal protein transmembrane 5
chr16_-_38118003 0.29 ENSDART00000058667
si:dkey-23o4.6
chr9_-_42418470 0.29 ENSDART00000144353
calcitonin receptor-like a
chr16_+_36671064 0.29 ENSDART00000109703
collagen, type VI, alpha 4a
chr5_-_30382925 0.28 ENSDART00000125381
grass carp reovirus (GCRV)-induced gene 2o
chr3_-_20040636 0.28 ENSDART00000104118
ataxin 7-like 3
chr5_+_69747417 0.27 ENSDART00000153717
si:ch211-275j6.5
chr1_+_44127292 0.27 ENSDART00000160542
calcium binding protein 2a
chr6_+_52350443 0.27 ENSDART00000151612
ENSDART00000151349
si:ch211-239j9.1
chr10_+_26747755 0.27 ENSDART00000100329
coagulation factor IXb
chr16_-_12173399 0.27 ENSDART00000142574
calsyntenin 3
chr2_-_9059955 0.26 ENSDART00000022768
adenylate kinase 5
chr7_+_23515966 0.26 ENSDART00000186893
ENSDART00000186189
zgc:109889
chr3_+_23029934 0.26 ENSDART00000110343
N-acetylglutamate synthase
chr9_-_43538328 0.26 ENSDART00000140526
zinc finger protein 385B
chr1_-_23040358 0.25 ENSDART00000146871
adhesion G protein-coupled receptor L3.1
chr12_-_558201 0.25 ENSDART00000168586
ENSDART00000158355
brain specific kinase 146
chr17_+_16564921 0.25 ENSDART00000151904
forkhead box N3
chr21_-_43015383 0.25 ENSDART00000065097
dihydropyrimidinase-like 3
chr13_+_9432501 0.25 ENSDART00000058064
zgc:123321
chr20_-_34750045 0.25 ENSDART00000186130
zinc finger protein 395b
chr20_+_4060839 0.25 ENSDART00000178565
tripartite motif containing 67
chr12_+_3022882 0.24 ENSDART00000122905
Rac family small GTPase 3b
chr2_+_20430366 0.24 ENSDART00000155108
si:ch211-153l6.6
chr10_-_36927594 0.24 ENSDART00000162046
seizure related 6 homolog a
chr15_+_25438714 0.24 ENSDART00000154164
apoptosis-inducing factor, mitochondrion-associated, 4
chr21_-_14811058 0.23 ENSDART00000143100
phosphohistidine phosphatase 1
chr20_+_19512727 0.23 ENSDART00000063696
all-trans retinoic acid-induced differentiation factor
chr6_+_40714811 0.23 ENSDART00000153868
coiled-coil domain containing 36
chr6_-_35779348 0.23 ENSDART00000191159
bone morphogenetic protein/retinoic acid inducible neural-specific 3a, tandem duplicate 1
chr1_+_25801648 0.23 ENSDART00000129471
guanylate cyclase 1 soluble subunit beta 1
chr12_-_41684729 0.23 ENSDART00000184461
Janus kinase and microtubule interacting protein 3
chr1_+_39482588 0.23 ENSDART00000181790
teneurin transmembrane protein 3
chr1_+_51721851 0.23 ENSDART00000040397
peroxiredoxin 2
chr5_-_6377865 0.23 ENSDART00000031775
zgc:73226
chr2_+_44571200 0.23 ENSDART00000098132
kelch-like family member 24a
chr20_+_32552912 0.22 ENSDART00000009691
Scm polycomb group protein like 4
chr10_-_33621739 0.21 ENSDART00000142655
ENSDART00000128049
hormonally up-regulated Neu-associated kinase
chr24_+_40529346 0.21 ENSDART00000168548

chr5_-_55933420 0.21 ENSDART00000050966
solute carrier family 25, member 46
chr12_+_1139690 0.21 ENSDART00000160442

chr7_-_11596450 0.21 ENSDART00000173863
StAR-related lipid transfer (START) domain containing 5
chr13_-_2010191 0.21 ENSDART00000161021
ENSDART00000124134
GDNF family receptor alpha like
chr3_+_26145013 0.21 ENSDART00000162546
ENSDART00000129561
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr9_+_54039006 0.21 ENSDART00000112441
toll-like receptor 7
chr24_-_26328721 0.20 ENSDART00000125468
apolipoprotein Db
chr13_-_29421331 0.20 ENSDART00000150228
choline O-acetyltransferase a
chr16_-_31622777 0.20 ENSDART00000137311
ENSDART00000002930
PHD finger protein 20 like 1
chr11_-_1935883 0.20 ENSDART00000172885
Fas apoptotic inhibitory molecule 2b
chr21_+_22840246 0.20 ENSDART00000151621
baculoviral IAP repeat containing 2
chr16_+_51326237 0.20 ENSDART00000168525

chr11_-_2838699 0.20 ENSDART00000066189
LHFPL tetraspan subfamily member 5a
chr8_-_2434282 0.20 ENSDART00000137262
ENSDART00000134044
voltage-dependent anion channel 3
chr5_-_2282256 0.19 ENSDART00000064012
carbonic anhydrase IV a
chr5_-_42904329 0.19 ENSDART00000112807
chemokine (C-X-C motif) ligand 20
chr22_+_1556948 0.19 ENSDART00000159050
si:ch211-255f4.8
chr8_-_39952727 0.19 ENSDART00000181310
calcium binding protein 1a
chr8_-_25422186 0.18 ENSDART00000113492
ENSDART00000131736
potassium voltage-gated channel, KQT-like subfamily, member 2a
chr17_+_45602640 0.18 ENSDART00000153822
si:ch211-202f3.4
chr9_+_21826724 0.18 ENSDART00000101985
zgc:162944
chr6_+_612594 0.18 ENSDART00000150903
kynureninase
chr6_-_24053404 0.18 ENSDART00000168511
si:dkey-44g17.6
chr8_+_8845932 0.18 ENSDART00000112028
si:ch211-180f4.1
chr1_-_55118745 0.17 ENSDART00000133915
SERTA domain containing 2a
chr22_+_18469004 0.17 ENSDART00000061430
cartilage intermediate layer protein 2
chr15_+_9327252 0.17 ENSDART00000144381
sarcoglycan, gamma
chr22_-_26865181 0.17 ENSDART00000138311
heme oxygenase 2a
chr14_-_413273 0.17 ENSDART00000163976
ENSDART00000179907
FAT atypical cadherin 4
chr4_+_5255041 0.17 ENSDART00000137966
coiled-coil domain containing 167
chr14_-_7207961 0.17 ENSDART00000167994
ENSDART00000166532
storkhead box 2b
chr3_+_36424055 0.17 ENSDART00000170318
si:ch1073-443f11.2
chr10_-_26766780 0.17 ENSDART00000146666
MCF.2 cell line derived transforming sequence b
chr2_+_16160906 0.17 ENSDART00000135783
selenoprotein J
chr1_-_54063520 0.17 ENSDART00000171722
single-pass membrane protein with aspartate-rich tail 1b
chr11_+_40812590 0.16 ENSDART00000186690
ERBB receptor feedback inhibitor 1a
chr10_-_35236949 0.16 ENSDART00000145804
yippee-like 2a
chr2_-_1548330 0.16 ENSDART00000082155
ENSDART00000108481
ENSDART00000111272
Dab, reelin signal transducer, homolog 1b (Drosophila)
chr20_+_41756996 0.16 ENSDART00000186393
family with sequence similarity 184, member A
chr4_+_19700308 0.16 ENSDART00000027919
paired box 4
chr9_+_34127005 0.16 ENSDART00000167384
ENSDART00000078065
coagulation factor V
chr20_+_41664350 0.15 ENSDART00000186247
family with sequence similarity 184, member A
chr18_+_35128685 0.15 ENSDART00000151579
si:ch211-195m9.3
chr17_-_30702411 0.15 ENSDART00000114358
zgc:194392
chr22_-_31060579 0.15 ENSDART00000182376
cullin-associated and neddylation-dissociated 2 (putative)
chr8_+_26141680 0.15 ENSDART00000078334
cadherin, EGF LAG seven-pass G-type receptor 3
chr20_+_66857 0.15 ENSDART00000114999
leucine rich repeat and fibronectin type III domain containing 2b
chr8_-_17987547 0.15 ENSDART00000112699
ENSDART00000061747
fucose-1-phosphate guanylyltransferase
chr14_-_2209742 0.15 ENSDART00000054889
protocadherin 2 alpha b 5
chr21_+_21195487 0.14 ENSDART00000181746
ENSDART00000184832
RPTOR independent companion of MTOR, complex 2b
chr11_-_26832685 0.14 ENSDART00000153519
IQ motif and Sec7 domain 1b
chr16_+_12836143 0.14 ENSDART00000067741
calcium channel, voltage-dependent, gamma subunit 6b
chr15_+_34592215 0.14 ENSDART00000099776
tetraspanin 13a
chr1_-_58975098 0.14 ENSDART00000189899

chr10_+_17776981 0.14 ENSDART00000141693
chemokine (C-C motif) ligand 19b
chr23_-_3511630 0.14 ENSDART00000019667
ring finger protein 114
chr18_-_47662696 0.14 ENSDART00000184260

chr8_+_52637507 0.14 ENSDART00000163830
si:dkey-90l8.3
chr13_+_7292061 0.13 ENSDART00000179504
Danio rerio neuroblast differentiation-associated protein AHNAK-like (LOC795051), mRNA.
chr21_+_45841731 0.13 ENSDART00000038657
fatty acid hydroxylase domain containing 2
chr2_+_36007449 0.13 ENSDART00000161837
laminin, gamma 2
chr14_-_4145594 0.13 ENSDART00000077348
caspase 3, apoptosis-related cysteine peptidase b
chr16_+_3068080 0.13 ENSDART00000160092
cytochrome b5 reductase 4
chr14_-_30141162 0.13 ENSDART00000053916
melatonin receptor 1A b
chr12_-_9132682 0.13 ENSDART00000066471
ADAM metallopeptidase domain 8b
chr23_+_7710447 0.13 ENSDART00000168199
kinesin family member 3B
chr4_-_2219705 0.13 ENSDART00000131046
si:ch73-278m9.1
chr13_+_15656042 0.13 ENSDART00000134240
MAP/microtubule affinity-regulating kinase 3a
chr22_+_23359369 0.13 ENSDART00000170886
DENN/MADD domain containing 1B
chr15_-_38154616 0.13 ENSDART00000099392
immunity-related GTPase family, q2
chr12_+_4222854 0.13 ENSDART00000144881
mitogen-activated protein kinase 7
chr21_-_32060993 0.12 ENSDART00000131651
si:ch211-160j14.2
chr18_+_15616167 0.12 ENSDART00000080454
solute carrier family 17 (vesicular glutamate transporter), member 8
chr25_-_19420949 0.12 ENSDART00000181338
microtubule-associated protein 1Ab
chr2_-_7843451 0.12 ENSDART00000163265
si:ch211-38m6.7
chr9_+_7724152 0.12 ENSDART00000061716
motor neuron and pancreas homeobox 2a
chr21_-_38853737 0.12 ENSDART00000184100
toll-like receptor 22
chr10_-_34916208 0.12 ENSDART00000187371
cyclin A1
chr1_+_6862917 0.12 ENSDART00000182953
erb-b2 receptor tyrosine kinase 4a
chr10_-_14556978 0.12 ENSDART00000126643
zgc:153395
chr9_-_40765868 0.12 ENSDART00000138634
ATP-binding cassette, sub-family A (ABC1), member 12
chr7_-_22632690 0.12 ENSDART00000165245
si:dkey-112a7.4
chr2_+_29491314 0.12 ENSDART00000181774
discs, large (Drosophila) homolog-associated protein 1a
chr4_+_20051478 0.12 ENSDART00000143642
late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
chr7_+_49800849 0.11 ENSDART00000164838
ENSDART00000187888
si:ch211-102l7.3
chr23_-_41965557 0.11 ENSDART00000144183
solute carrier family 1 (glutamate transporter), member 7b
chr22_+_1586060 0.11 ENSDART00000160793
si:ch211-255f4.11
chr3_+_7808459 0.11 ENSDART00000162374
hook microtubule-tethering protein 2
chr4_-_27897160 0.11 ENSDART00000066924
ENSDART00000066925
ENSDART00000193020
TBC1 domain family, member 22a
chr4_-_73136420 0.11 ENSDART00000160907
si:ch73-170d6.3
chr7_-_71829649 0.11 ENSDART00000160449
calcium channel, voltage-dependent, beta 2a
chr22_-_10121880 0.11 ENSDART00000002348
retinol dehydrogenase 5 (11-cis/9-cis)
chr8_+_17987778 0.11 ENSDART00000133429
leucine-rich repeats and IQ motif containing 3
chr19_+_12915498 0.11 ENSDART00000132892
collagen triple helix repeat containing 1a
chr20_-_29864390 0.11 ENSDART00000161834
ENSDART00000132278
ring finger protein 144ab
chr2_-_16216568 0.11 ENSDART00000173758
Rho guanine nucleotide exchange factor (GEF) 4
chr9_+_45227028 0.11 ENSDART00000185579
adenosine deaminase, RNA-specific, B1b
chr9_-_25989989 0.11 ENSDART00000090052
Rho GTPase activating protein 15
chr14_+_36521005 0.11 ENSDART00000192286
si:dkey-237h12.3
chr8_+_17987215 0.11 ENSDART00000113605
leucine-rich repeats and IQ motif containing 3
chr2_+_20605925 0.11 ENSDART00000191510
olfactomedin-like 2Bb
chr14_-_28534563 0.11 ENSDART00000054088
zgc:113364

Network of associatons between targets according to the STRING database.

First level regulatory network of pou1f1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0005986 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
0.2 0.7 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.1 0.4 GO:0019062 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
0.1 0.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.4 GO:0099563 modification of synaptic structure(GO:0099563)
0.1 0.4 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 0.4 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 0.2 GO:0035971 peptidyl-histidine dephosphorylation(GO:0035971)
0.1 0.2 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.4 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.4 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.1 0.2 GO:0097052 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.1 0.2 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.1 0.2 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.1 0.2 GO:1903385 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.1 0.2 GO:0090076 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.1 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.2 GO:0060547 negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.0 0.5 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.5 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.8 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.2 GO:0006788 heme oxidation(GO:0006788)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.4 GO:0032264 IMP salvage(GO:0032264)
0.0 0.2 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.1 GO:1902514 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.2 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.0 0.2 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.2 GO:0019430 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 3.0 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.1 GO:0043584 nose development(GO:0043584)
0.0 0.3 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.2 GO:0060005 reflex(GO:0060004) vestibular reflex(GO:0060005)
0.0 0.2 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 0.9 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.1 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.5 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.3 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0048313 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.0 0.7 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.3 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.1 GO:0048730 epidermis morphogenesis(GO:0048730)
0.0 0.1 GO:0070285 pigment cell development(GO:0070285)
0.0 0.0 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.1 GO:0006531 aspartate metabolic process(GO:0006531)
0.0 0.6 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.2 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.1 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.3 GO:0006415 translational termination(GO:0006415)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:0021654 rhombomere boundary formation(GO:0021654)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.2 GO:0042119 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 0.1 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.1 GO:0030279 negative regulation of ossification(GO:0030279)
0.0 0.0 GO:0071706 tumor necrosis factor production(GO:0032640) tumor necrosis factor superfamily cytokine production(GO:0071706)
0.0 0.0 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.1 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.5 GO:0030282 bone mineralization(GO:0030282)
0.0 0.1 GO:0060386 synapse assembly involved in innervation(GO:0060386)
0.0 0.1 GO:0050909 sensory perception of taste(GO:0050909)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.2 GO:0031673 H zone(GO:0031673)
0.1 0.4 GO:0071914 prominosome(GO:0071914)
0.0 0.1 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0 0.1 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.0 0.6 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 0.9 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0044545 NSL complex(GO:0044545)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 0.4 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.4 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.1 0.4 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.1 0.4 GO:0034618 arginine binding(GO:0034618)
0.1 0.3 GO:0015462 protein-transmembrane transporting ATPase activity(GO:0015462) efflux transmembrane transporter activity(GO:0015562)
0.1 0.3 GO:0001635 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.1 0.5 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.1 0.3 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.2 GO:0101006 protein histidine phosphatase activity(GO:0101006)
0.1 0.3 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.7 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.2 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.2 GO:0032052 bile acid binding(GO:0032052)
0.0 0.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 2.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0004134 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.0 0.1 GO:0102344 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.4 GO:0008308 voltage-gated chloride channel activity(GO:0005247) voltage-gated anion channel activity(GO:0008308)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.0 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:0036122 BMP binding(GO:0036122)
0.0 0.0 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.0 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis