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PRJEB1986: zebrafish developmental stages transcriptome

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Results for pax7a+pax7b+prop1

Z-value: 1.10

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Transcription factors associated with pax7a+pax7b+prop1

Gene Symbol Gene ID Gene Info
ENSDARG00000039756 PROP paired-like homeobox 1
ENSDARG00000070818 paired box 7b
ENSDARG00000100398 paired box 7a
ENSDARG00000109950 PROP paired-like homeobox 1
ENSDARG00000111233 paired box 7a
ENSDARG00000114449 PROP paired-like homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pax7adr11_v1_chr11_+_41243094_412430940.788.4e-05Click!
pax7bdr11_v1_chr23_+_20931030_20931030-0.493.3e-02Click!
prop1dr11_v1_chr13_+_8677166_8677304-0.077.9e-01Click!

Activity profile of pax7a+pax7b+prop1 motif

Sorted Z-values of pax7a+pax7b+prop1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_-_48983690 5.60 ENSDART00000182359

chr9_-_22099536 5.55 ENSDART00000101923

chr3_-_31079186 5.28 ENSDART00000145636
ENSDART00000140569
elongin B
elongin B
chr20_-_52902693 4.38 ENSDART00000166115
ENSDART00000161050
cathepsin Bb
chr4_+_18804317 4.07 ENSDART00000101043
solute carrier family 26 (anion exchanger), member 3, tandem duplicate 2
chr3_+_21225750 3.91 ENSDART00000139213
zgc:153968
chr9_-_22129788 3.60 ENSDART00000124272
ENSDART00000175417
crystallin, gamma M2d8
chr8_+_43056153 3.56 ENSDART00000186377
prion protein a
chr22_+_7738966 3.38 ENSDART00000147073
si:ch73-44m9.5
chr1_+_17676745 3.19 ENSDART00000030665
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr21_-_1012269 3.16 ENSDART00000159835

chr17_-_37395460 3.08 ENSDART00000148160
ENSDART00000075975
cysteine-rich protein 1
chr15_-_46779934 3.00 ENSDART00000085136
chloride channel 2c
chr25_+_31227747 2.95 ENSDART00000033872
troponin I type 2a (skeletal, fast), tandem duplicate 1
chr22_+_7439186 2.94 ENSDART00000190667
zgc:92041
chr4_-_8043839 2.85 ENSDART00000190047
ENSDART00000057567
si:ch211-240l19.5
chr5_+_2815021 2.79 ENSDART00000020472
4-hydroxyphenylpyruvate dioxygenase a
chr15_+_45640906 2.76 ENSDART00000149361
ENSDART00000149079
S-antigen; retina and pineal gland (arrestin) b
chr16_-_28658341 2.72 ENSDART00000148456
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr16_-_11798994 2.68 ENSDART00000135408
cornifelin
chr17_-_200316 2.58 ENSDART00000190561

chr25_-_19224298 2.57 ENSDART00000149917
aggrecan b
chr22_-_26865181 2.43 ENSDART00000138311
heme oxygenase 2a
chr16_+_2820340 2.38 ENSDART00000092299
ENSDART00000192931
ENSDART00000148512
si:dkey-288i20.2
chr24_-_29586082 2.38 ENSDART00000136763
vav 3 guanine nucleotide exchange factor a
chr9_+_2574122 2.32 ENSDART00000166326
ENSDART00000191822
si:ch73-167c12.2
chr25_+_31276842 2.28 ENSDART00000187238
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr10_+_45071603 2.26 ENSDART00000186505
ENSDART00000157573
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr16_-_12173554 2.26 ENSDART00000110567
ENSDART00000155935
calsyntenin 3
chr21_+_31150438 2.24 ENSDART00000065366
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr8_+_47633438 2.20 ENSDART00000139096
si:ch211-251b21.1
chr16_-_13281380 2.18 ENSDART00000103882
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b
chr21_+_28958471 2.17 ENSDART00000144331
ENSDART00000005929
protein phosphatase 3, catalytic subunit, alpha isozyme
chr7_+_24573721 2.17 ENSDART00000173938
ENSDART00000173681
si:dkeyp-75h12.7
chr11_-_11266882 2.16 ENSDART00000020256
lengsin, lens protein with glutamine synthetase domain
chr20_-_40755614 2.13 ENSDART00000061247
connexin 32.3
chr12_+_16168342 2.12 ENSDART00000079326
ENSDART00000170024
low density lipoprotein receptor-related protein 2b
chr1_-_50859053 2.11 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
chr16_-_12173399 2.09 ENSDART00000142574
calsyntenin 3
chr24_-_27400017 2.05 ENSDART00000145829
chemokine (C-C motif) ligand 34b, duplicate 1
chr21_+_45841731 2.00 ENSDART00000038657
fatty acid hydroxylase domain containing 2
chr5_+_32206378 1.98 ENSDART00000126873
ENSDART00000051361
myosin, heavy polypeptide 2, fast muscle specific
chr25_-_20024829 1.95 ENSDART00000140182
ENSDART00000174776
CCR4-NOT transcription complex, subunit 4a
chr10_+_45089820 1.87 ENSDART00000175481
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr1_-_15797663 1.87 ENSDART00000177122
sarcoglycan zeta
chr12_+_48480632 1.81 ENSDART00000158157
Rho GTPase activating protein 44
chr24_-_38110779 1.80 ENSDART00000147783
c-reactive protein, pentraxin-related
chr13_+_6342410 1.77 ENSDART00000065228
CUB and Sushi multiple domains 1a
chr19_+_5480327 1.76 ENSDART00000148794
junction plakoglobin b
chr15_-_33925851 1.74 ENSDART00000187807
ENSDART00000187780
myelin associated glycoprotein
chr19_+_43297546 1.70 ENSDART00000168002
lysosomal protein transmembrane 5
chr5_-_41494831 1.69 ENSDART00000051081
eukaryotic translation elongation factor 2, like 2
chr21_+_25660613 1.69 ENSDART00000134017
si:dkey-17e16.15
chr9_-_3866707 1.68 ENSDART00000010378
myosin IIIB
chr5_-_5326010 1.67 ENSDART00000161946
pre-B-cell leukemia homeobox 3a
chr4_+_61995745 1.67 ENSDART00000171539

chr11_+_29770966 1.67 ENSDART00000088624
ENSDART00000124471
retinitis pigmentosa GTPase regulator b
chr15_+_44366556 1.66 ENSDART00000133449
guanylate cyclase 1 soluble subunit alpha 2
chr17_-_36896560 1.65 ENSDART00000045287
microtubule-associated protein, RP/EB family, member 3a
chr23_-_41965557 1.63 ENSDART00000144183
solute carrier family 1 (glutamate transporter), member 7b
chr21_+_31150773 1.63 ENSDART00000126205
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr18_+_26337869 1.62 ENSDART00000109257
si:ch211-234p18.3
chr16_-_22781446 1.62 ENSDART00000144107
lens epithelial protein
chr17_-_12336987 1.60 ENSDART00000172001
synaptosomal-associated protein, 25b
chr4_-_22207873 1.60 ENSDART00000142140
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr23_-_306796 1.59 ENSDART00000143125
ankyrin repeat and sterile alpha motif domain containing 1Aa
chr24_-_7697274 1.54 ENSDART00000186077
synaptotagmin Vb
chr3_-_21280373 1.54 ENSDART00000003939
synaptogyrin 1a
chr13_-_29420885 1.53 ENSDART00000024225
choline O-acetyltransferase a
chr12_-_2522487 1.53 ENSDART00000022471
ENSDART00000145213
mitogen-activated protein kinase 8b
chr6_-_37403444 1.51 ENSDART00000136314
cystathionase (cystathionine gamma-lyase), like
chr3_+_62000822 1.50 ENSDART00000106680
retinoic acid induced 1
chr17_+_5793248 1.48 ENSDART00000153743
retinitis pigmentosa 1-like 1a
chr14_-_14659023 1.47 ENSDART00000170355
ENSDART00000159888
ENSDART00000172241
NAD(P) dependent steroid dehydrogenase-like
chr2_+_44571200 1.47 ENSDART00000098132
kelch-like family member 24a
chr4_-_2219705 1.47 ENSDART00000131046
si:ch73-278m9.1
chr7_+_23515966 1.46 ENSDART00000186893
ENSDART00000186189
zgc:109889
chr25_+_37293312 1.45 ENSDART00000086737
ENSDART00000161595
si:dkey-234i14.9
chr6_+_39905021 1.44 ENSDART00000064904
endonuclease, polyU-specific
chr1_+_55140970 1.44 ENSDART00000039807
myoglobin
chr8_-_13184989 1.44 ENSDART00000135738
zgc:194990
chr6_+_3282809 1.43 ENSDART00000187444
ENSDART00000187407
ENSDART00000191883
lysine (K)-specific demethylase 4A, genome duplicate a
chr9_-_35334642 1.43 ENSDART00000157195
neural cell adhesion molecule 2
chr25_-_19420949 1.42 ENSDART00000181338
microtubule-associated protein 1Ab
chr11_+_42474694 1.42 ENSDART00000056048
ENSDART00000184710
si:ch1073-165f9.2
chr20_-_5291012 1.37 ENSDART00000122892
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 3
chr3_-_23407720 1.37 ENSDART00000155658
Rap guanine nucleotide exchange factor (GEF)-like 1
chr8_+_52637507 1.37 ENSDART00000163830
si:dkey-90l8.3
chr11_-_1935883 1.36 ENSDART00000172885
Fas apoptotic inhibitory molecule 2b
chr11_+_13224281 1.36 ENSDART00000102557
ENSDART00000178706
ATP-binding cassette, sub-family B (MDR/TAP), member 11b
chr22_-_19102256 1.36 ENSDART00000171866
ENSDART00000166295
polymerase (RNA) mitochondrial (DNA directed)
chr4_+_9400012 1.35 ENSDART00000191960
transmembrane and tetratricopeptide repeat containing 1
chr4_-_815871 1.35 ENSDART00000067455
dihydropyrimidinase-like 5b
chr23_-_24825863 1.35 ENSDART00000112493
synaptotagmin VIa
chr21_+_21195487 1.33 ENSDART00000181746
ENSDART00000184832
RPTOR independent companion of MTOR, complex 2b
chr25_+_5821910 1.33 ENSDART00000161035
chromosome 12 open reading frame 75
chr24_-_31425799 1.32 ENSDART00000157998
cyclic nucleotide gated channel beta 3, tandem duplicate 1
chr13_+_2442841 1.31 ENSDART00000114456
ENSDART00000137124
ENSDART00000193737
ENSDART00000189722
ENSDART00000187485
ARFGEF family member 3
chr10_+_21722892 1.30 ENSDART00000162855
protocadherin 1 gamma 13
chr1_-_25370281 1.29 ENSDART00000050445
tripartite motif containing 2a
chr9_-_36924388 1.27 ENSDART00000059756
v-ral simian leukemia viral oncogene homolog Ba (ras related)
chr18_+_38908903 1.25 ENSDART00000159834
myosin VAa
chr21_-_20939488 1.25 ENSDART00000039043
regulator of G protein signaling 7 binding protein b
chr25_+_31267268 1.25 ENSDART00000181239
troponin I type 2a (skeletal, fast), tandem duplicate 3
chr13_+_15838151 1.24 ENSDART00000008987
kinesin light chain 1a
chr4_-_69189894 1.22 ENSDART00000169596
si:ch211-209j12.1
chr3_+_28953274 1.20 ENSDART00000133528
ENSDART00000103602
lectin, galactoside-binding, soluble, 2a
chr10_-_5581487 1.20 ENSDART00000141943
spleen tyrosine kinase
chr14_-_9713549 1.20 ENSDART00000193356
ENSDART00000166739
si:zfos-2326c3.2
chr5_+_37903790 1.18 ENSDART00000162470
transmembrane protease, serine 4b
chr13_-_11644806 1.18 ENSDART00000169953
dynactin 1b
chr23_-_1660708 1.16 ENSDART00000175138

chr2_-_48153945 1.16 ENSDART00000146553
phosphofructokinase, platelet b
chr18_-_8877077 1.16 ENSDART00000137266
si:dkey-95h12.2
chr14_-_49063157 1.15 ENSDART00000021260
septin 8b
chr25_+_3327071 1.15 ENSDART00000136131
ENSDART00000133243
lactate dehydrogenase Bb
chr6_+_24420523 1.14 ENSDART00000185461
transforming growth factor, beta receptor III
chr16_+_47207691 1.14 ENSDART00000062507
islet cell autoantigen 1
chr2_-_37043905 1.14 ENSDART00000056514
guanine nucleotide binding protein (G protein), gamma 7
chr20_-_7583486 1.13 ENSDART00000144729
ubiquitin specific peptidase 24
chr20_+_18945057 1.13 ENSDART00000035447
myotubularin related protein 9
chr19_-_27858033 1.12 ENSDART00000103898
ENSDART00000144884
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
chr19_-_42045372 1.12 ENSDART00000144275
trio Rho guanine nucleotide exchange factor a
chr10_-_105100 1.10 ENSDART00000145716
tetratricopeptide repeat domain 3
chr3_+_16722014 1.10 ENSDART00000008711
glycogen synthase 1 (muscle)
chr10_+_15255198 1.08 ENSDART00000139047
ENSDART00000172107
ENSDART00000183413
ENSDART00000185314
very low density lipoprotein receptor
chr14_-_45512807 1.08 ENSDART00000173172
si:ch211-114c17.1
chr2_+_29491314 1.08 ENSDART00000181774
discs, large (Drosophila) homolog-associated protein 1a
chr2_+_50608099 1.07 ENSDART00000185805
ENSDART00000111135
neuronal differentiation 6b
chr15_-_22074315 1.07 ENSDART00000149830
dopamine receptor D2a
chr19_-_5103141 1.05 ENSDART00000150952
triosephosphate isomerase 1a
chr11_-_2131280 1.04 ENSDART00000008409
calcium binding and coiled-coil domain 1b
chr16_+_16933002 1.04 ENSDART00000173163
myosin, heavy chain 14, non-muscle
chr7_+_24645186 1.03 ENSDART00000150118
ENSDART00000150233
ENSDART00000087691
glucosidase, beta (bile acid) 2
chr17_+_28533102 1.01 ENSDART00000156218
MAM domain containing glycosylphosphatidylinositol anchor 2a
chr12_+_18681477 1.01 ENSDART00000127981
ENSDART00000143979
regulator of G protein signaling 9b
chr20_+_715739 1.00 ENSDART00000136768
myosin VIa
chr17_+_16564921 1.00 ENSDART00000151904
forkhead box N3
chr24_-_11908115 0.98 ENSDART00000184329
transmembrane 9 superfamily member 1
chr10_+_17776981 0.98 ENSDART00000141693
chemokine (C-C motif) ligand 19b
chr21_-_22635245 0.98 ENSDART00000115224
ENSDART00000101782
nectin cell adhesion molecule 1a
chr4_-_63165848 0.97 ENSDART00000183789

chr6_+_9870192 0.97 ENSDART00000150894
si:ch211-222n4.6
chr3_-_59297532 0.97 ENSDART00000187991

chr16_-_34401412 0.97 ENSDART00000054020
human immunodeficiency virus type I enhancer binding protein 3b
chr5_+_71802014 0.97 ENSDART00000124939
ENSDART00000097164
LIM homeobox 3
chr25_+_7504314 0.96 ENSDART00000163231
interferon induced transmembrane protein 5
chr14_+_36521005 0.96 ENSDART00000192286
si:dkey-237h12.3
chr12_-_6880694 0.96 ENSDART00000171846
protocadherin-related 15b
chr9_+_54039006 0.96 ENSDART00000112441
toll-like receptor 7
chr25_-_31898552 0.96 ENSDART00000156128
si:ch73-330k17.3
chr24_-_31843173 0.96 ENSDART00000185782
STEAP family member 2, metalloreductase
chr3_+_26019426 0.95 ENSDART00000135389
ENSDART00000182411
FAD-dependent oxidoreductase domain containing 2
chr24_+_15670013 0.95 ENSDART00000185826

chr20_+_23173710 0.95 ENSDART00000074172
sarcoglycan, beta (dystrophin-associated glycoprotein)
chr12_-_41684729 0.95 ENSDART00000184461
Janus kinase and microtubule interacting protein 3
chr8_+_25767610 0.94 ENSDART00000062406
calcium channel, voltage-dependent, L type, alpha 1S subunit, b
chr3_-_6519691 0.94 ENSDART00000165273
ENSDART00000179882
ENSDART00000172292
si:ch73-157i16.3
chr6_+_13024448 0.94 ENSDART00000104768
paroxysmal nonkinesigenic dyskinesia
chr21_+_6751405 0.93 ENSDART00000037265
ENSDART00000146371
olfactomedin 1b
chr8_-_22326744 0.93 ENSDART00000137645
centrosomal protein 104
chr10_+_42423318 0.93 ENSDART00000134282
neuropeptide Y receptor Y8a
chr2_-_3403020 0.93 ENSDART00000092741
synaptosomal-associated protein, 47
chr14_-_858985 0.93 ENSDART00000148687
ENSDART00000149375
solute carrier family 34 (type II sodium/phosphate cotransporter), member 1a
chr9_+_34127005 0.92 ENSDART00000167384
ENSDART00000078065
coagulation factor V
chr7_+_27898091 0.92 ENSDART00000186451
ENSDART00000173510
tubby bipartite transcription factor
chr22_-_14739491 0.91 ENSDART00000133385
low density lipoprotein receptor-related protein 1Ba
chr5_+_64842730 0.91 ENSDART00000144732
leucine rich repeat containing 8 VRAC subunit Ab
chr12_+_18578597 0.90 ENSDART00000134944
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, b
chr18_+_9810642 0.90 ENSDART00000143965
si:dkey-266j7.2
chr2_+_47708853 0.89 ENSDART00000124307
muscleblind-like splicing regulator 1
chr1_-_6085750 0.89 ENSDART00000138891
si:ch1073-345a8.1
chr3_-_23406964 0.89 ENSDART00000114723
Rap guanine nucleotide exchange factor (GEF)-like 1
chr6_+_32882821 0.88 ENSDART00000075780
growth hormone releasing hormone receptor b
chr6_+_44812444 0.87 ENSDART00000189478
ENSDART00000164653
ENSDART00000184534
ENSDART00000175473
cell adhesion molecule L1-like b
chr3_-_13921173 0.86 ENSDART00000159177
ENSDART00000165174
si:dkey-61n16.5
chr6_-_55347616 0.85 ENSDART00000172081
PDX1 C-terminal inhibiting factor 1
chr4_+_9669717 0.85 ENSDART00000004604
si:dkey-153k10.9
chr22_-_17844117 0.85 ENSDART00000159363

chr1_+_52560549 0.85 ENSDART00000167514
ATP-binding cassette, sub-family A (ABC1), member 1A
chr17_+_38476300 0.84 ENSDART00000123298
StAR-related lipid transfer (START) domain containing 9
chr15_-_17618800 0.83 ENSDART00000157185
ADAM metallopeptidase with thrombospondin type 1 motif, 15b
chr25_+_33192404 0.83 ENSDART00000193592
zgc:171719
chr11_+_41540862 0.83 ENSDART00000173210
potassium voltage-gated channel, shaker-related subfamily, beta member 2 a
chr21_-_42202792 0.82 ENSDART00000124708
gamma-aminobutyric acid (GABA) A receptor, alpha 6b
chr21_-_36571804 0.82 ENSDART00000138129
WW and C2 domain containing 1
chr21_-_18993110 0.82 ENSDART00000144086
si:ch211-222n4.6
chr15_-_37543591 0.81 ENSDART00000180400
lysine (K)-specific methyltransferase 2Bb
chr15_-_40267485 0.81 ENSDART00000152253
potassium inwardly-rectifying channel, subfamily J, member 13
chr11_+_2855430 0.81 ENSDART00000172837
kinesin family member 21B
chr19_+_14573998 0.80 ENSDART00000022076
family with sequence similarity 46, member Bb
chr18_+_45781516 0.79 ENSDART00000168840
ribosomal protein L35a
chr10_-_4375190 0.79 ENSDART00000016102

chr18_+_34225520 0.79 ENSDART00000126115
vomeronasal 2 receptor, l1
chr21_-_5958387 0.79 ENSDART00000130521
si:ch73-209e20.5
chr1_+_44127292 0.79 ENSDART00000160542
calcium binding protein 2a
chr15_+_34592215 0.76 ENSDART00000099776
tetraspanin 13a
chr19_-_9867001 0.76 ENSDART00000091695
calcium channel, voltage-dependent, gamma subunit 7a
chr18_+_39487486 0.75 ENSDART00000126978
acyl-CoA dehydrogenase long chain
chr16_+_32029090 0.75 ENSDART00000041054
transmembrane channel-like 4

Network of associatons between targets according to the STRING database.

First level regulatory network of pax7a+pax7b+prop1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.8 3.2 GO:0015868 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.5 1.6 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.5 1.5 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.5 2.8 GO:0006572 tyrosine catabolic process(GO:0006572)
0.5 2.8 GO:0006788 heme oxidation(GO:0006788)
0.4 1.7 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.4 1.2 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.4 3.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.4 1.8 GO:0002159 desmosome assembly(GO:0002159)
0.3 1.0 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.3 1.0 GO:0021611 facial nerve formation(GO:0021611)
0.3 1.0 GO:0044406 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
0.3 1.0 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.3 0.9 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.3 2.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.3 0.8 GO:0090219 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.2 1.0 GO:0015677 copper ion import(GO:0015677)
0.2 1.2 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.2 2.8 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.2 1.5 GO:0009092 homoserine metabolic process(GO:0009092) cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344) transsulfuration(GO:0019346)
0.2 0.8 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.2 0.6 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.2 1.5 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.2 0.8 GO:0051876 pigment granule dispersal(GO:0051876)
0.2 1.7 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.2 1.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.2 4.1 GO:0015701 bicarbonate transport(GO:0015701)
0.2 3.4 GO:0014823 response to activity(GO:0014823)
0.2 1.4 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.2 0.6 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.2 0.9 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.2 1.7 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.7 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 2.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.6 GO:0060986 regulation of endocrine process(GO:0044060) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938) endocrine hormone secretion(GO:0060986)
0.1 0.7 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 6.6 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.3 GO:0035994 response to muscle stretch(GO:0035994)
0.1 0.4 GO:1900158 negative regulation of chondrocyte differentiation(GO:0032331) negative regulation of cartilage development(GO:0061037) negative regulation of chondrocyte development(GO:0061182) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158) negative regulation of bone development(GO:1903011)
0.1 1.4 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.8 GO:0032475 otolith formation(GO:0032475)
0.1 2.2 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.1 1.6 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 1.2 GO:0061718 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 3.2 GO:0009636 response to toxic substance(GO:0009636)
0.1 0.4 GO:0055071 manganese ion homeostasis(GO:0055071)
0.1 3.0 GO:0055064 chloride ion homeostasis(GO:0055064)
0.1 1.0 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.1 4.0 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 3.4 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.1 1.2 GO:0090303 positive regulation of wound healing(GO:0090303)
0.1 1.0 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 0.6 GO:0046822 regulation of nucleocytoplasmic transport(GO:0046822)
0.1 1.3 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 1.5 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.1 3.0 GO:0002548 monocyte chemotaxis(GO:0002548)
0.1 0.8 GO:0098900 regulation of action potential(GO:0098900)
0.1 1.3 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.1 0.3 GO:0032782 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.1 3.5 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.1 0.7 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.1 0.5 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 1.1 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1 0.3 GO:0035988 chondrocyte proliferation(GO:0035988)
0.1 0.7 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.1 0.7 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 1.4 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.1 0.3 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.1 0.5 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.1 1.1 GO:0050796 regulation of insulin secretion(GO:0050796)
0.1 0.9 GO:0016082 synaptic vesicle priming(GO:0016082)
0.1 2.0 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.3 GO:1902267 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 1.5 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 1.1 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 0.5 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.4 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.0 0.8 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 1.8 GO:0001878 response to yeast(GO:0001878)
0.0 0.8 GO:0060078 regulation of postsynaptic membrane potential(GO:0060078)
0.0 0.3 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 1.2 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.4 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 2.7 GO:0006414 translational elongation(GO:0006414)
0.0 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:0006660 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.6 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 1.6 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.6 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.3 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.0 2.2 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.4 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.5 GO:0006415 translational termination(GO:0006415)
0.0 4.3 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.5 GO:0009583 phototransduction(GO:0007602) detection of light stimulus(GO:0009583)
0.0 1.5 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.6 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 1.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.0 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.3 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.4 GO:0000097 sulfur amino acid biosynthetic process(GO:0000097)
0.0 0.3 GO:1990399 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.0 1.1 GO:1903844 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.0 1.2 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.5 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0050909 sensory perception of taste(GO:0050909)
0.0 2.5 GO:0031101 fin regeneration(GO:0031101)
0.0 0.2 GO:0097531 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.2 GO:0001881 receptor recycling(GO:0001881)
0.0 0.3 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.7 GO:0007548 sex differentiation(GO:0007548)
0.0 0.6 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.4 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.0 GO:0097264 self proteolysis(GO:0097264)
0.0 0.3 GO:0032098 regulation of appetite(GO:0032098)
0.0 1.5 GO:0042461 photoreceptor cell development(GO:0042461)
0.0 0.7 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 2.3 GO:0007601 visual perception(GO:0007601)
0.0 0.2 GO:0072576 liver morphogenesis(GO:0072576)
0.0 0.4 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 0.4 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 1.0 GO:0007599 hemostasis(GO:0007599)
0.0 2.2 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.2 GO:0071679 commissural neuron axon guidance(GO:0071679)
0.0 0.4 GO:0045727 positive regulation of translation(GO:0045727)
0.0 1.2 GO:0031098 stress-activated protein kinase signaling cascade(GO:0031098)
0.0 1.1 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 1.0 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.5 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.9 GO:0070509 calcium ion import(GO:0070509)
0.0 0.2 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 5.3 GO:0030891 VCB complex(GO:0030891)
0.6 2.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.4 2.2 GO:0005955 calcineurin complex(GO:0005955)
0.3 1.6 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.2 0.5 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.2 0.5 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.2 0.6 GO:0032838 cell projection cytoplasm(GO:0032838)
0.2 6.5 GO:0005861 troponin complex(GO:0005861)
0.1 2.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.2 GO:0001772 immunological synapse(GO:0001772)
0.1 1.5 GO:0031045 dense core granule(GO:0031045)
0.1 2.8 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 2.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 2.8 GO:0035371 microtubule plus-end(GO:0035371)
0.1 1.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.7 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.4 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.4 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.1 1.0 GO:0032420 stereocilium(GO:0032420)
0.1 1.1 GO:0034361 very-low-density lipoprotein particle(GO:0034361)
0.1 1.1 GO:0000243 commitment complex(GO:0000243)
0.1 0.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 1.0 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 1.1 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.8 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.1 GO:0030667 secretory granule membrane(GO:0030667)
0.1 0.9 GO:0005903 brush border(GO:0005903)
0.1 1.0 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 7.0 GO:0016459 myosin complex(GO:0016459)
0.1 0.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 2.1 GO:0098978 glutamatergic synapse(GO:0098978)
0.1 1.0 GO:0030057 desmosome(GO:0030057)
0.0 1.4 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 1.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.8 GO:0030315 T-tubule(GO:0030315)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 0.2 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.6 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.6 GO:0044545 NSL complex(GO:0044545)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 0.5 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 2.9 GO:0005871 kinesin complex(GO:0005871)
0.0 1.2 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 6.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 2.7 GO:0043025 neuronal cell body(GO:0043025)
0.0 2.5 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 5.3 GO:0005764 lysosome(GO:0005764)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.3 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 9.9 GO:0043005 neuron projection(GO:0043005)
0.0 0.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.4 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.3 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.5 GO:0005884 actin filament(GO:0005884)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.4 GO:0032432 actin filament bundle(GO:0032432)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.9 2.7 GO:0015562 protein-transmembrane transporting ATPase activity(GO:0015462) efflux transmembrane transporter activity(GO:0015562)
0.8 3.2 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.6 2.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.5 1.5 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.5 3.7 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.5 2.8 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.4 3.6 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.4 1.7 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.4 2.2 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.3 2.2 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.3 2.0 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.3 1.1 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.3 1.1 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.3 1.1 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.2 0.7 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.2 1.0 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2 0.7 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.2 1.2 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.2 1.4 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.2 4.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.2 0.9 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.2 3.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.2 1.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 0.8 GO:0090556 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.2 1.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 1.5 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.2 0.9 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.2 1.5 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.9 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.5 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 1.5 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 1.7 GO:0033691 sialic acid binding(GO:0033691)
0.1 1.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 2.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.4 GO:0015369 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.1 1.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 1.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 1.3 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 1.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.4 GO:0031005 filamin binding(GO:0031005)
0.1 0.6 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.1 4.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.0 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 1.5 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 2.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 1.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.3 GO:0015126 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.1 0.5 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 3.0 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.6 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 1.4 GO:0019825 oxygen transporter activity(GO:0005344) oxygen binding(GO:0019825)
0.1 2.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.4 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.1 2.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 2.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.6 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.8 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.7 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 1.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 1.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.9 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 0.4 GO:0031419 cobalamin binding(GO:0031419)
0.1 1.4 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.3 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.7 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 3.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 2.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 1.8 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 1.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.8 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 2.1 GO:0042562 hormone binding(GO:0042562)
0.0 0.4 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 1.3 GO:0019003 GDP binding(GO:0019003)
0.0 0.9 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 7.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 6.3 GO:0003774 motor activity(GO:0003774)
0.0 0.3 GO:0016936 galactoside binding(GO:0016936)
0.0 0.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0005113 patched binding(GO:0005113)
0.0 1.1 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 1.6 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 0.5 GO:0002039 p53 binding(GO:0002039)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.6 GO:0031267 small GTPase binding(GO:0031267)
0.0 2.7 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.7 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0043295 glutathione binding(GO:0043295)
0.0 3.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.3 GO:0016229 steroid dehydrogenase activity(GO:0016229)
0.0 2.9 GO:0042277 peptide binding(GO:0042277)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 1.1 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.9 GO:0005507 copper ion binding(GO:0005507)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 1.9 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.0 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 2.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 1.1 PID REELIN PATHWAY Reelin signaling pathway
0.1 1.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 1.6 PID RAS PATHWAY Regulation of Ras family activation
0.1 1.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.8 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.7 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.4 1.6 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.2 1.8 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 2.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 1.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 2.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 3.4 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 1.0 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 0.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 0.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 1.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 0.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 0.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.7 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.7 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.5 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 2.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.5 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.3 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors