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PRJEB1986: zebrafish developmental stages transcriptome

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Results for onecut3a+onecut3b

Z-value: 0.67

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Transcription factors associated with onecut3a+onecut3b

Gene Symbol Gene ID Gene Info
ENSDARG00000056395 one cut homeobox 3a
ENSDARG00000091059 one cut homeobox 3b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
onecut3adr11_v1_chr22_+_20461488_204614880.734.4e-04Click!
onecut3bdr11_v1_chr2_+_57504073_575040730.502.9e-02Click!

Activity profile of onecut3a+onecut3b motif

Sorted Z-values of onecut3a+onecut3b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr24_-_38113208 1.68 ENSDART00000079003
c-reactive protein, pentraxin-related
chr18_+_642889 1.66 ENSDART00000189007

chr14_+_35748385 1.35 ENSDART00000064617
ENSDART00000074671
ENSDART00000172803
glutamate receptor, ionotropic, AMPA 2b
chr15_-_34418525 1.33 ENSDART00000147582
alkylglycerol monooxygenase
chr1_-_21409877 1.29 ENSDART00000102782
glutamate receptor, ionotropic, AMPA 2a
chr17_-_20897407 1.27 ENSDART00000149481
ankyrin 3b
chr14_+_35748206 1.24 ENSDART00000177391
glutamate receptor, ionotropic, AMPA 2b
chr3_-_60142530 1.23 ENSDART00000153247
si:ch211-120g10.1
chr4_-_5291256 1.22 ENSDART00000150864
si:ch211-214j24.9
chr1_+_19332837 1.21 ENSDART00000078594
tyrosinase-related protein 1b
chr3_-_28665291 1.19 ENSDART00000151670
F-box and leucine-rich repeat protein 16
chr3_-_28120092 1.18 ENSDART00000151143
RNA binding fox-1 homolog 1
chr12_+_26512569 1.14 ENSDART00000066264
chondroadherin
chr1_+_37391716 1.07 ENSDART00000191986
SPARC-like 1
chr11_+_6819050 1.05 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr17_-_20897250 0.99 ENSDART00000088106
ankyrin 3b
chr16_-_12173554 0.98 ENSDART00000110567
ENSDART00000155935
calsyntenin 3
chr11_-_10798021 0.97 ENSDART00000167112
ENSDART00000179725
ENSDART00000091923
ENSDART00000185825
solute carrier family 4, sodium bicarbonate transporter, member 10a
chr2_-_32505091 0.95 ENSDART00000141884
ENSDART00000056639
Fas apoptotic inhibitory molecule 2a
chr8_-_23081511 0.94 ENSDART00000142015
ENSDART00000135764
ENSDART00000147021
si:dkey-70p6.1
chr21_+_4116437 0.90 ENSDART00000167791
ENSDART00000123759
Rap guanine nucleotide exchange factor (GEF) 1b
chr2_+_47582488 0.90 ENSDART00000149967
secretogranin II (chromogranin C), b
chr12_+_10116912 0.90 ENSDART00000189630
si:dkeyp-118b1.2
chr5_-_71460556 0.89 ENSDART00000108804
bone morphogenetic protein/retinoic acid inducible neural-specific 1
chr8_-_14052349 0.89 ENSDART00000135811
ATPase plasma membrane Ca2+ transporting 3a
chr5_+_19309877 0.87 ENSDART00000190338
RUN and SH3 domain containing 2
chr6_+_3828560 0.85 ENSDART00000185273
ENSDART00000179091
glutamate decarboxylase 1b
chr10_-_33156789 0.82 ENSDART00000192268
ENSDART00000182065
ENSDART00000081170
cut-like homeobox 1a
chr19_-_17526735 0.81 ENSDART00000189391
thyroid hormone receptor beta
chr1_-_23157583 0.81 ENSDART00000144208
adhesion G protein-coupled receptor L3.1
chr8_+_40477264 0.79 ENSDART00000085559
glucokinase (hexokinase 4)
chr22_+_17359346 0.79 ENSDART00000145434
G protein-coupled receptor 52
chr14_+_49376011 0.78 ENSDART00000020961
TNFAIP3 interacting protein 1
chr24_-_23320223 0.78 ENSDART00000135846
zinc finger homeobox 4
chr4_+_7827261 0.78 ENSDART00000129568
phytanoyl-CoA 2-hydroxylase
chr20_+_22130284 0.77 ENSDART00000025575
clock circadian regulator a
chr2_-_56387041 0.77 ENSDART00000036240
ceramide synthase 4b
chr25_-_9805269 0.76 ENSDART00000192048
leucine rich repeat containing 4C
chr16_-_12173399 0.76 ENSDART00000142574
calsyntenin 3
chr18_+_3579829 0.75 ENSDART00000158763
ENSDART00000182850
ENSDART00000162754
ENSDART00000178789
ENSDART00000172656
leucine-rich repeats and calponin homology (CH) domain containing 3
chr4_-_9214288 0.74 ENSDART00000067309
arginine vasopressin receptor 1Ab
chr7_-_68419830 0.74 ENSDART00000191606

chr21_-_23475361 0.73 ENSDART00000156658
ENSDART00000157454
neural cell adhesion molecule 1a
chr2_+_5887626 0.73 ENSDART00000147831
si:ch211-168b3.1
chr10_-_31782616 0.73 ENSDART00000128839
fasciculation and elongation protein zeta 1 (zygin I)
chr23_-_15216654 0.70 ENSDART00000131649
sulfatase 2b
chr2_+_25860344 0.70 ENSDART00000178841
solute carrier family 7, member 14a
chr15_-_7598294 0.70 ENSDART00000165898
glucan (1,4-alpha-), branching enzyme 1b
chr13_-_31166544 0.70 ENSDART00000146250
ENSDART00000132129
ENSDART00000139591
mitogen-activated protein kinase 8a
chr15_-_7598542 0.68 ENSDART00000173092
glucan (1,4-alpha-), branching enzyme 1b
chr15_+_22394074 0.66 ENSDART00000109931
OAF homolog a (Drosophila)
chr17_-_26507289 0.65 ENSDART00000155616
coiled-coil serine-rich protein 2a
chr16_+_21738194 0.64 ENSDART00000163688
Danio rerio si:ch211-154o6.4 (si:ch211-154o6.4), mRNA.
chr16_-_44127307 0.61 ENSDART00000104583
ENSDART00000151936
ENSDART00000058685
ENSDART00000190830
zinc finger protein, FOG family member 2a
chr15_-_34785594 0.60 ENSDART00000154256
gamma-aminobutyric acid (GABA) B receptor, 1a
chr21_+_6212844 0.60 ENSDART00000150301
formin binding protein 1b
chr7_-_41693004 0.59 ENSDART00000121509
MAM and LDL receptor class A domain containing 1
chr18_-_46380471 0.59 ENSDART00000144444
ENSDART00000086772
solute carrier family 19 (thiamine transporter), member 3b
chr2_+_47581997 0.58 ENSDART00000112579
secretogranin II (chromogranin C), b
chr14_+_21783229 0.57 ENSDART00000170784
ankyrin repeat domain 13 family, member D
chr22_-_3092136 0.57 ENSDART00000157620
inhibitor of growth family, member 5a
chr7_-_36096582 0.56 ENSDART00000188507

chr14_-_31893996 0.55 ENSDART00000173222
G protein-coupled receptor 101
chr3_+_39853788 0.55 ENSDART00000154869
calcium channel, voltage-dependent, T type, alpha 1H subunit a
chr9_+_32358514 0.54 ENSDART00000144608
phospholipase C like 1
chr15_+_17446796 0.54 ENSDART00000157189
sorting nexin 19b
chr2_-_6262441 0.53 ENSDART00000092190
ADP-ribosylation factor-like 14
chr6_+_40714811 0.52 ENSDART00000153868
coiled-coil domain containing 36
chr6_+_40992409 0.52 ENSDART00000151419
transforming growth factor, alpha
chr3_-_30434016 0.52 ENSDART00000150958
leucine rich repeat containing 4Ba
chr6_-_33707278 0.50 ENSDART00000188103
microtubule associated serine/threonine kinase 2
chr24_-_36680261 0.50 ENSDART00000059507
chemokine (C-C motif) receptor 10
chr21_-_17482465 0.49 ENSDART00000004548
BarH-like homeobox 1b
chr16_-_26255877 0.49 ENSDART00000146214
Ets2 repressor factor like 1
chr18_+_15876385 0.49 ENSDART00000142527
early endosome antigen 1
chr10_-_7785930 0.47 ENSDART00000043961
ENSDART00000111058
myeloid-specific peroxidase
chr1_-_36151377 0.45 ENSDART00000037516
zinc finger protein 827
chr20_-_40367493 0.44 ENSDART00000075096
sphingomyelin phosphodiesterase, acid-like 3A
chr1_+_40140498 0.43 ENSDART00000101640
zgc:152658
chr19_+_19512515 0.43 ENSDART00000180065
JAZF zinc finger 1a
chr12_+_32729470 0.43 ENSDART00000175712
RNA binding fox-1 homolog 3a
chr18_-_26894732 0.42 ENSDART00000147735
ENSDART00000188938

si:dkey-24l11.2
chr21_-_39058490 0.42 ENSDART00000114885
aldehyde dehydrogenase 3 family, member A2b
chr17_-_8169774 0.42 ENSDART00000091828
spectrin repeat containing, nuclear envelope 1b
chr12_-_30338779 0.41 ENSDART00000192511
von Willebrand factor A domain containing 2
chr10_-_41352502 0.41 ENSDART00000052971
ENSDART00000128156
RAB11 family interacting protein 1 (class I) b
chr13_+_36144341 0.41 ENSDART00000182930
ENSDART00000187327
si:ch211-259k16.3
chr21_+_3901775 0.41 ENSDART00000053609
dolichyldiphosphatase 1
chr5_-_67661102 0.40 ENSDART00000013605
zinc finger and BTB domain containing 20
chr3_-_44753325 0.40 ENSDART00000074543
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr3_-_32071468 0.39 ENSDART00000121979

chr13_+_49727333 0.39 ENSDART00000168799
ENSDART00000037559
geranylgeranyl diphosphate synthase 1
chr25_+_22017182 0.36 ENSDART00000156517
si:dkey-217l24.1
chr5_+_42136359 0.36 ENSDART00000083731
transient receptor potential cation channel, subfamily V, member 1
chr21_+_17768174 0.34 ENSDART00000141380
retinoid X receptor, alpha a
chr22_-_7669624 0.34 ENSDART00000189617

chr3_-_8399774 0.34 ENSDART00000190238
ENSDART00000113140
ENSDART00000132949
RNA binding fox-1 homolog 3b
chr23_+_43870886 0.33 ENSDART00000102658
ENSDART00000149088
nuclear transcription factor, X-box binding-like 1
chr21_+_18877130 0.33 ENSDART00000136893
si:dkey-65l23.2
chr14_+_11946395 0.33 ENSDART00000193290
FERM and PDZ domain containing 3
chr2_+_21309272 0.32 ENSDART00000141322
zinc finger and BTB domain containing 47a
chr7_+_40658003 0.32 ENSDART00000172435
limb development membrane protein 1
chr15_+_17441734 0.31 ENSDART00000153729
sorting nexin 19b
chr19_-_21766461 0.31 ENSDART00000104279
zinc finger protein 516
chr10_-_28477023 0.31 ENSDART00000137008
bobby sox homolog (Drosophila)
chr15_-_33325019 0.30 ENSDART00000181092
ENSDART00000168920
neurobeachin b
chr13_-_37383625 0.30 ENSDART00000192888
ENSDART00000100322
ENSDART00000138934
potassium voltage-gated channel, subfamily H (eag-related), member 5b
chr2_-_17044959 0.30 ENSDART00000090260
chloride channel, voltage-sensitive 2a
chr7_+_30933867 0.29 ENSDART00000156325
tight junction protein 1a
chr10_-_15405564 0.29 ENSDART00000020665
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr25_-_35046114 0.28 ENSDART00000185267
zgc:165555
chr20_+_42978499 0.27 ENSDART00000138793
si:ch211-203k16.3
chr5_-_1999417 0.27 ENSDART00000155437
ENSDART00000145781
si:ch211-160e1.5
chr14_-_4044545 0.26 ENSDART00000169527
sorting nexin 25
chr2_+_30281444 0.26 ENSDART00000172756
si:dkey-82k12.13
chr23_+_25832689 0.26 ENSDART00000138907
hepatocyte nuclear factor 4, alpha
chr16_+_22587661 0.26 ENSDART00000129612
ENSDART00000142241
Src homology 2 domain containing E
chr23_-_20002459 0.25 ENSDART00000163396
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
chr16_-_26435431 0.25 ENSDART00000187526
multiple EGF-like-domains 8
chr14_+_36628131 0.25 ENSDART00000188625
ENSDART00000125345
si:dkey-237h12.3
chr1_+_51391082 0.25 ENSDART00000063936
autophagy related 4D, cysteine peptidase a
chr17_-_45247332 0.25 ENSDART00000016815
tau tubulin kinase 2a
chr25_+_31267268 0.24 ENSDART00000181239
troponin I type 2a (skeletal, fast), tandem duplicate 3
chr16_-_17541890 0.23 ENSDART00000131328
chloride channel, voltage-sensitive 1b
chr12_-_47793857 0.23 ENSDART00000161294
DPY30 domain containing 2
chr8_+_9866351 0.22 ENSDART00000133985
potassium voltage-gated channel, Shal-related subfamily, member 1
chr17_+_23937262 0.22 ENSDART00000113276
si:ch211-189k9.2
chr22_-_23067859 0.22 ENSDART00000137873
protein tyrosine phosphatase, receptor type, C
chr9_+_51147380 0.22 ENSDART00000003913
interferon induced with helicase C domain 1
chr22_-_38360205 0.21 ENSDART00000162055
MAP/microtubule affinity-regulating kinase 1
chr3_+_32443395 0.21 ENSDART00000188447
proline rich 12b
chr16_+_19732543 0.21 ENSDART00000149901
ENSDART00000052927
twist family bHLH transcription factor 1b
chr25_-_11088839 0.20 ENSDART00000154748
synaptic vesicle glycoprotein 2Bb
chr12_+_47794089 0.19 ENSDART00000160726
polymerase (RNA) III (DNA directed) polypeptide A
chr18_-_20560007 0.19 ENSDART00000141367
ENSDART00000090186
si:ch211-238n5.4
chr23_-_35195908 0.19 ENSDART00000122429
Kruppel-like factor 15
chr18_-_44611252 0.18 ENSDART00000173095
sprouty-related, EVH1 domain containing 3
chr18_+_8937718 0.18 ENSDART00000138115
si:dkey-5i3.1
chr7_+_63325819 0.18 ENSDART00000085612
ENSDART00000161436
protocadherin 7b
chr4_+_5842433 0.18 ENSDART00000124085
ENSDART00000179848
ubiquitin specific peptidase 18
chr9_+_32930622 0.17 ENSDART00000100928
cyclic nucleotide gated channel alpha 4
chr5_+_56268436 0.17 ENSDART00000021159
LIM homeobox 1b
chr20_-_13660600 0.17 ENSDART00000063826
si:ch211-122h15.4
chr6_-_17999776 0.17 ENSDART00000183048
ENSDART00000181577
ENSDART00000170597
regulatory associated protein of MTOR, complex 1
chr14_-_41243180 0.16 ENSDART00000184548
dystrophin related protein 2
chr2_+_42871831 0.16 ENSDART00000171393
EFR3 homolog A (S. cerevisiae)
chr12_-_18883079 0.16 ENSDART00000178619
shisa family member 8b
chr20_-_3403033 0.16 ENSDART00000092264
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr25_+_10929790 0.16 ENSDART00000045182

chr3_-_58165254 0.15 ENSDART00000093031
SNU13 homolog, small nuclear ribonucleoprotein a (U4/U6.U5)
chr24_-_15131831 0.15 ENSDART00000028410
CD226 molecule
chr6_-_16456093 0.15 ENSDART00000083305
ENSDART00000181640
solute carrier family 19 (thiamine transporter), member 2
chr1_-_46663997 0.15 ENSDART00000134450
emopamil binding protein-like
chr20_-_13660767 0.13 ENSDART00000127654
si:ch211-122h15.4
chr11_-_22605981 0.13 ENSDART00000186923
myogenin
chr18_+_13248956 0.13 ENSDART00000080709
phospholipase C, gamma 2
chr22_-_6144428 0.13 ENSDART00000106118
si:dkey-19a16.4
chr16_-_31525290 0.12 ENSDART00000109996
WNT1 inducible signaling pathway protein 1b
chr3_-_29506960 0.12 ENSDART00000141720
cytohesin 4a
chr12_+_48204891 0.12 ENSDART00000190534
ENSDART00000164427
nodal-related 2
chr21_-_43482426 0.12 ENSDART00000192901
ankyrin repeat domain 46a
chr24_-_39826865 0.11 ENSDART00000089232
solute carrier family 12 (potassium/chloride transporter), member 7b
chr1_+_47391404 0.11 ENSDART00000113559
B cell CLL/lymphoma 9
chr23_+_16908012 0.10 ENSDART00000133946
si:dkey-147f3.8
chr8_-_14484599 0.10 ENSDART00000057644
LIM homeobox 4
chr16_-_2650341 0.10 ENSDART00000128169
ENSDART00000155432
ENSDART00000103722
lysophospholipase-like 1
chr5_-_3118346 0.10 ENSDART00000167554
heat shock transcription factor family member 5
chr7_+_2228276 0.10 ENSDART00000064294
si:dkey-187j14.4
chr2_+_22042745 0.09 ENSDART00000132039
thymocyte selection-associated high mobility group box
chr15_-_39948635 0.09 ENSDART00000114836
mutS homolog 5
chr5_+_56026031 0.09 ENSDART00000050970
frizzled class receptor 9a
chr7_+_73649686 0.08 ENSDART00000185589
si:dkey-46i9.1
chr10_-_11840353 0.08 ENSDART00000127581
tripartite motif containing 23
chr12_-_35582683 0.08 ENSDART00000167933
SEC24 homolog C, COPII coat complex component
chr20_+_18992679 0.08 ENSDART00000147105
ENSDART00000152811
L-threonine dehydrogenase
chr2_-_45510223 0.08 ENSDART00000113058
G protein signaling modulator 2
chr9_+_19421841 0.06 ENSDART00000159090
ENSDART00000084771
phosphodiesterase 9A
chr7_+_33372680 0.05 ENSDART00000193436
ENSDART00000099988
glucuronic acid epimerase b
chr21_-_40799404 0.05 ENSDART00000147405
ENSDART00000157512
zgc:162239
chr16_+_11683548 0.05 ENSDART00000138000
si:dkey-250k15.7
chr7_-_4461104 0.05 ENSDART00000023090
ENSDART00000140770
solute carrier family 12 (sodium/potassium/chloride transporters), member 10, tandem duplicate 1
chr5_-_14211487 0.04 ENSDART00000135731
neuropeptide FF receptor 1 like 2
chr10_-_39052264 0.04 ENSDART00000144036
immunoglobulin superfamily, member 5a
chr8_-_621142 0.04 ENSDART00000187576
ENSDART00000190316
si:ch211-87m7.2
chr2_+_44781185 0.03 ENSDART00000187103
ENSDART00000147292
ENSDART00000098123
endothelin converting enzyme 2a
chr19_+_43256986 0.02 ENSDART00000182336
diacylglycerol kinase delta
chr17_-_45378473 0.02 ENSDART00000132969
zinc finger protein 106a
chr6_-_40352215 0.02 ENSDART00000103992
tubulin tyrosine ligase-like family, member 3
chr19_-_38539670 0.01 ENSDART00000136775
collagen, type XVI, alpha 1
chr20_+_52546186 0.00 ENSDART00000110777
ENSDART00000153377
ENSDART00000153013
ENSDART00000042704
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr20_-_3004126 0.00 ENSDART00000064390
peptidylprolyl isomerase (cyclophilin)-like 4
chr23_+_25993686 0.00 ENSDART00000053993
WNT1 inducible signaling pathway protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of onecut3a+onecut3b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.3 0.9 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.3 1.3 GO:0046485 ether lipid metabolic process(GO:0046485)
0.2 0.7 GO:0021961 posterior commissure morphogenesis(GO:0021961)
0.2 1.2 GO:0097066 response to thyroid hormone(GO:0097066)
0.2 0.8 GO:0046551 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.2 1.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.8 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.5 GO:0032655 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.1 0.3 GO:1903332 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.1 0.9 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 1.3 GO:0048899 anterior lateral line development(GO:0048899)
0.1 0.8 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.1 0.7 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.1 0.5 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 0.5 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.1 0.5 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.1 0.7 GO:0035860 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 0.2 GO:0002833 response to tumor cell(GO:0002347) natural killer cell cytokine production(GO:0002370) immune response to tumor cell(GO:0002418) natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of response to biotic stimulus(GO:0002833) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 1.0 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.3 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 1.5 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.0 0.2 GO:0032608 interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648) positive regulation of interferon-beta production(GO:0032728)
0.0 0.5 GO:2000377 regulation of reactive oxygen species metabolic process(GO:2000377)
0.0 0.8 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.5 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.2 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 1.4 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 1.3 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.6 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.3 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.1 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.2 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.9 GO:1903038 negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 0.8 GO:0009648 photoperiodism(GO:0009648)
0.0 0.3 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.2 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 1.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.4 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.4 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.4 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 0.8 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.3 GO:0032526 response to retinoic acid(GO:0032526)
0.0 1.0 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.1 GO:0045117 azole transport(GO:0045117)
0.0 0.8 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.6 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 0.1 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 0.1 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.1 1.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 0.3 GO:0072380 TRC complex(GO:0072380)
0.1 4.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.6 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.1 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.6 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 1.5 GO:0030141 secretory granule(GO:0030141)
0.0 1.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.2 GO:0042575 DNA polymerase complex(GO:0042575)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.3 0.9 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.3 3.9 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.2 0.8 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 1.3 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.8 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.8 GO:0070888 E-box binding(GO:0070888)
0.1 0.5 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.6 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.7 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 1.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.7 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 1.0 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.8 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.4 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 1.3 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.1 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.1 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.0 0.4 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.0 0.2 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.5 GO:0019957 chemokine binding(GO:0019956) C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.8 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.3 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.8 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation