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PRJEB1986: zebrafish developmental stages transcriptome

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Results for onecut1+onecutl

Z-value: 2.15

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Transcription factors associated with onecut1+onecutl

Gene Symbol Gene ID Gene Info
ENSDARG00000007982 one cut homeobox 1
ENSDARG00000040253 one cut domain, family member, like
ENSDARG00000112251 one cut homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
onecutldr11_v1_chr16_-_29528198_29528198-0.541.7e-02Click!
onecut1dr11_v1_chr18_+_38755023_387550240.039.1e-01Click!

Activity profile of onecut1+onecutl motif

Sorted Z-values of onecut1+onecutl motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_61205711 12.17 ENSDART00000055062
parvalbumin 1
chr6_-_609880 7.81 ENSDART00000149248
ENSDART00000148867
ENSDART00000149414
ENSDART00000148552
ENSDART00000148391
lectin, galactoside-binding, soluble, 2b
chr2_-_51794472 7.31 ENSDART00000186652

chr2_+_35240485 7.22 ENSDART00000179804
tenascin R (restrictin, janusin)
chr12_-_22524388 7.18 ENSDART00000020942
sex hormone-binding globulin
chr15_-_12270857 7.09 ENSDART00000170093
si:dkey-36i7.3
chr15_-_37846047 6.60 ENSDART00000184837
heat shock cognate 70
chr5_+_55626693 5.93 ENSDART00000168908
ENSDART00000161412
neurotrophic tyrosine kinase, receptor, type 2b
chr8_-_4327473 5.80 ENSDART00000134378
cut-like homeobox 2b
chr8_-_40555340 5.79 ENSDART00000163348
NPC1 like intracellular cholesterol transporter 1
chr14_-_7885707 5.77 ENSDART00000029981
protein phosphatase 3, catalytic subunit, beta isozyme
chr4_+_20318127 5.64 ENSDART00000028856
ENSDART00000132909
calcium channel, voltage-dependent, L type, alpha 1C subunit
chr16_+_52105227 5.50 ENSDART00000150025
ENSDART00000097863
si:ch73-373m9.1
chr12_-_4781801 5.47 ENSDART00000167490
ENSDART00000121718
microtubule-associated protein tau a
chr21_-_27881752 5.10 ENSDART00000132583
neurexin 2a
chr25_+_4760489 4.98 ENSDART00000167399

chr2_+_35240764 4.96 ENSDART00000015827
tenascin R (restrictin, janusin)
chr13_+_16521898 4.85 ENSDART00000122557
potassium large conductance calcium-activated channel, subfamily M, alpha member 1a
chr3_-_41791178 4.85 ENSDART00000049687
galectin-related inter-fiber protein
chr3_-_12890670 4.82 ENSDART00000159934
ENSDART00000188607
BTB (POZ) domain containing 17b
chr8_-_31919624 4.79 ENSDART00000085573
regulator of G protein signaling 7 binding protein a
chr14_+_22172047 4.56 ENSDART00000114750
ENSDART00000148259
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr19_-_9829965 4.51 ENSDART00000136842
ENSDART00000142766
calcium channel, voltage-dependent, gamma subunit 8a
chr21_-_41588129 4.35 ENSDART00000164125
creb3 regulatory factor
chr6_+_55174744 4.34 ENSDART00000023562
synaptotagmin 2
chr9_-_35557397 4.23 ENSDART00000100681
neural cell adhesion molecule 2
chr13_-_23270576 4.23 ENSDART00000132828
si:dkey-103j14.5
chr20_-_39273505 4.04 ENSDART00000153114
clusterin
chr5_-_23429228 4.02 ENSDART00000049291
glutamate receptor, ionotropic, AMPA 3a
chr20_+_3108597 4.01 ENSDART00000133435
si:ch73-212j7.1
chr2_+_32843133 3.98 ENSDART00000018501
opsin 4.1
chr15_-_24869826 3.97 ENSDART00000127047
tumor suppressor candidate 5a
chr12_+_39685485 3.93 ENSDART00000163403

chr8_+_23916647 3.92 ENSDART00000143152
copine Va
chr14_-_2933185 3.91 ENSDART00000161677
ENSDART00000162446
ENSDART00000109378
si:dkey-201i24.6
chr10_+_1638876 3.80 ENSDART00000184484
ENSDART00000060946
ENSDART00000181251
small G protein signaling modulator 1b
chr20_+_25575391 3.75 ENSDART00000063108
cytochrome P450, family 2, subfamily P, polypeptide 8
chr20_+_33981946 3.65 ENSDART00000131775
si:dkey-51e6.1
chr20_-_44575103 3.64 ENSDART00000192573
UBX domain protein 2A
chr1_-_49932040 3.61 ENSDART00000048281
cytochrome P450, family 2, subfamily U, polypeptide 1
chr15_+_30157602 3.60 ENSDART00000047248
ENSDART00000123937
nemo-like kinase, type 2
chr12_-_3756405 3.57 ENSDART00000150839
family with sequence similarity 57, member Bb
chr9_+_54417141 3.56 ENSDART00000056810
dopamine receptor D1b
chr19_+_27479563 3.53 ENSDART00000049368
ENSDART00000185426
alpha tubulin acetyltransferase 1
chr6_-_24143923 3.53 ENSDART00000157948
si:ch73-389b16.1
chr16_+_10346277 3.53 ENSDART00000081092
si:dkeyp-77h1.4
chr24_-_30091937 3.43 ENSDART00000148249
phospholipid phosphatase related 4b
chr15_-_14375452 3.39 ENSDART00000160675
ENSDART00000164028
ENSDART00000171642
D4, zinc and double PHD fingers family 1
chr23_+_44611864 3.36 ENSDART00000145905
ENSDART00000132361
enolase 3, (beta, muscle)
chr16_-_8280885 3.30 ENSDART00000129068
ectonucleoside triphosphate diphosphohydrolase 3
chr20_-_51946052 3.21 ENSDART00000074325
dual specificity phosphatase 10
chr13_+_16522608 3.20 ENSDART00000182838
ENSDART00000143200
potassium large conductance calcium-activated channel, subfamily M, alpha member 1a
chr15_+_47418565 3.17 ENSDART00000155709
ClpB homolog, mitochondrial AAA ATPase chaperonin
chr8_+_7740004 3.13 ENSDART00000170184
ENSDART00000187811
FYVE, RhoGEF and PH domain containing 1
chr14_-_7045009 3.13 ENSDART00000112082
RUN and FYVE domain containing 1
chr18_-_12612699 3.12 ENSDART00000090335
homeodomain interacting protein kinase 2
chr12_+_24344611 3.11 ENSDART00000093094
neurexin 1a
chr1_-_21409877 3.10 ENSDART00000102782
glutamate receptor, ionotropic, AMPA 2a
chr24_-_17444067 3.10 ENSDART00000155843
contactin associated protein like 2a
chr9_-_18424844 3.09 ENSDART00000154351
ecto-NOX disulfide-thiol exchanger 1
chr1_+_2712956 3.06 ENSDART00000126093
glypican 6a
chr19_+_5674907 3.00 ENSDART00000042189
pyruvate dehydrogenase kinase, isozyme 2b
chr20_-_39273987 3.00 ENSDART00000127173
clusterin
chr25_+_19954576 2.96 ENSDART00000149335
potassium voltage-gated channel, shaker-related subfamily, member 1a
chr16_+_5184402 2.96 ENSDART00000156685
SOGA family member 3a
chr19_+_27479838 2.95 ENSDART00000103922
alpha tubulin acetyltransferase 1
chr23_+_28648864 2.94 ENSDART00000189096
L1 cell adhesion molecule, paralog a
chr5_+_3501859 2.94 ENSDART00000080486
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1
chr6_+_3828560 2.91 ENSDART00000185273
ENSDART00000179091
glutamate decarboxylase 1b
chr1_-_6085750 2.90 ENSDART00000138891
si:ch1073-345a8.1
chr4_+_10365857 2.89 ENSDART00000138890
potassium voltage-gated channel, Shal-related subfamily, member 2
chr9_+_46644633 2.88 ENSDART00000160285
solute carrier family 4 (anion exchanger), member 3
chr21_-_41305748 2.85 ENSDART00000170457
neuronal vesicle trafficking associated 2
chr21_+_9628854 2.82 ENSDART00000161753
ENSDART00000160711
mitogen-activated protein kinase 10
chr25_+_4837915 2.81 ENSDART00000168016
guanine nucleotide binding protein (G protein), beta 5a
chr17_-_20979077 2.80 ENSDART00000006676
phytanoyl-CoA 2-hydroxylase interacting protein-like a
chr17_+_8183393 2.76 ENSDART00000155957
tubby like protein 4b
chr4_+_7391400 2.75 ENSDART00000169111
ENSDART00000186395
troponin I4a
chr9_+_19039608 2.70 ENSDART00000055866
charged multivesicular body protein 2Ba
chr2_+_38608290 2.68 ENSDART00000159066
cadherin 24, type 2b
chr6_-_38419318 2.67 ENSDART00000138026
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr16_+_21738194 2.65 ENSDART00000163688
Danio rerio si:ch211-154o6.4 (si:ch211-154o6.4), mRNA.
chr9_-_23990416 2.60 ENSDART00000113176
collagen, type VI, alpha 3
chr22_+_110158 2.59 ENSDART00000143698
protein kinase, cAMP-dependent, regulatory, type II, alpha, B
chr24_+_39990695 2.58 ENSDART00000040281

chr8_-_45279411 2.57 ENSDART00000175207
ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr11_+_6819050 2.55 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr15_+_26399538 2.55 ENSDART00000159589
reticulon 4 receptor-like 1b
chr15_-_25392589 2.52 ENSDART00000124205
si:dkey-54n8.4
chr12_+_24344963 2.49 ENSDART00000191648
ENSDART00000183180
ENSDART00000088178
ENSDART00000189696
neurexin 1a
chr5_-_28102698 2.48 ENSDART00000138140
si:ch211-48m9.1
chr10_+_44057502 2.48 ENSDART00000183868
G protein-coupled receptor kinase 3
chr21_+_17768174 2.46 ENSDART00000141380
retinoid X receptor, alpha a
chr14_-_33894915 2.45 ENSDART00000143290
urotensin-related peptide 1
chr1_+_37391716 2.40 ENSDART00000191986
SPARC-like 1
chr5_-_22952156 2.40 ENSDART00000111146
si:ch211-26b3.4
chr5_-_13835461 2.35 ENSDART00000148297
ENSDART00000114841
adducin 2 (beta)
chr3_+_30257582 2.33 ENSDART00000159497
ENSDART00000103457
ENSDART00000121883
myosin binding protein C, fast type a
chr23_-_44494401 2.33 ENSDART00000114640
ENSDART00000148532
actin-like 6B
chr16_+_30301539 2.32 ENSDART00000186018

chr15_-_26686908 2.30 ENSDART00000185254
PITPNM family member 3
chr7_-_22132265 2.29 ENSDART00000125284
ENSDART00000112978
neuroligin 2a
chr10_+_37137464 2.29 ENSDART00000114909
CUE domain containing 1a
chr13_-_31829786 2.29 ENSDART00000138667
SERTA domain containing 4
chr8_-_3773374 2.26 ENSDART00000115036
BICD family like cargo adaptor 1
chr15_-_5467477 2.24 ENSDART00000123839
arrestin, beta 1
chr22_+_17359346 2.23 ENSDART00000145434
G protein-coupled receptor 52
chr15_-_34785594 2.21 ENSDART00000154256
gamma-aminobutyric acid (GABA) B receptor, 1a
chr7_-_52842007 2.20 ENSDART00000182710
microtubule-associated protein 1Aa
chr15_+_20543770 2.20 ENSDART00000092357
small G protein signaling modulator 2
chr19_+_42470396 2.15 ENSDART00000191679
si:dkey-166k12.1
chr3_-_23407720 2.12 ENSDART00000155658
Rap guanine nucleotide exchange factor (GEF)-like 1
chr13_+_42406883 2.12 ENSDART00000084354
cytoplasmic polyadenylation element binding protein 3
chr7_+_38510197 2.12 ENSDART00000173468
ENSDART00000100479
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr7_-_49892991 2.09 ENSDART00000126240
CD44 molecule (Indian blood group) a
chr12_-_13886952 2.07 ENSDART00000110503
ADAM metallopeptidase domain 11
chr25_+_31264155 2.06 ENSDART00000012256
troponin I type 2a (skeletal, fast), tandem duplicate 3
chr10_+_29199172 2.05 ENSDART00000148828
phosphatidylinositol binding clathrin assembly protein a
chr19_-_9882821 2.04 ENSDART00000147128
calcium channel, voltage-dependent, gamma subunit 7a
chr11_-_17713987 2.03 ENSDART00000090401
family with sequence similarity 19 (chemokine (C-C motif)-like), member A4b
chr24_-_35707552 2.03 ENSDART00000165199
microtubule-associated protein, RP/EB family, member 2
chr25_-_32311048 2.02 ENSDART00000181806
ENSDART00000086334

chr6_+_11438972 2.01 ENSDART00000029314
collagen, type V, alpha 2b
chr21_-_35853245 1.93 ENSDART00000172245
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr17_-_10025234 1.92 ENSDART00000008355
cofilin 2 (muscle)
chr18_+_3498989 1.90 ENSDART00000172373
olfactory marker protein a
chr24_-_21674950 1.89 ENSDART00000123216
ENSDART00000046211
ligand of numb-protein X 2a
chr3_-_28665291 1.89 ENSDART00000151670
F-box and leucine-rich repeat protein 16
chr14_+_45645024 1.88 ENSDART00000168278
si:ch211-276i12.4
chr16_-_44127307 1.87 ENSDART00000104583
ENSDART00000151936
ENSDART00000058685
ENSDART00000190830
zinc finger protein, FOG family member 2a
chr13_-_41908583 1.87 ENSDART00000136515
inositol polyphosphate multikinase a
chr21_+_9576176 1.86 ENSDART00000161289
ENSDART00000159899
ENSDART00000162834
mitogen-activated protein kinase 10
chr1_-_23308225 1.85 ENSDART00000137567
ENSDART00000008201
small integral membrane protein 14
chr17_-_10249095 1.85 ENSDART00000159963
somatostatin receptor 1a
chr3_-_47876427 1.80 ENSDART00000180844
ENSDART00000124480
adhesion G protein-coupled receptor L1a
chr9_+_11034314 1.78 ENSDART00000032695
acid-sensing (proton-gated) ion channel family member 4a
chr3_-_44753325 1.77 ENSDART00000074543
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr16_-_44649053 1.76 ENSDART00000184807

chr10_+_25222367 1.75 ENSDART00000042767
glutamate receptor, metabotropic 5a
chr21_+_1324416 1.72 ENSDART00000176557
transcription factor 4
chr3_-_60711127 1.72 ENSDART00000184119
UBA-like domain containing 2
chr18_-_37007294 1.71 ENSDART00000088309
mitogen-activated protein kinase kinase kinase 10
chr5_-_33769211 1.69 ENSDART00000133504
DAB2 interacting protein b
chr9_+_36356740 1.66 ENSDART00000139033
low density lipoprotein receptor-related protein 1Bb
chr7_+_32722227 1.66 ENSDART00000126565
si:ch211-150g13.3
chr6_-_40098641 1.65 ENSDART00000017402
inositol hexakisphosphate kinase 2b
chr4_+_7391110 1.65 ENSDART00000160708
ENSDART00000187823
troponin I4a
chr16_+_46453176 1.65 ENSDART00000132793
rapunzel 3
chr15_-_16121496 1.62 ENSDART00000128624
uncharacterized serine/threonine-protein kinase SgK494a
chr5_-_64355227 1.61 ENSDART00000170787
family with sequence similarity 78, member Aa
chr5_-_50371205 1.59 ENSDART00000157800
si:ch73-280o22.2
chr10_-_14536399 1.59 ENSDART00000186501
haloacid dehalogenase-like hydrolase domain containing 2
chr7_-_41693004 1.58 ENSDART00000121509
MAM and LDL receptor class A domain containing 1
chr22_-_13649588 1.57 ENSDART00000131877
si:ch211-279g13.1
chr18_-_37007061 1.57 ENSDART00000136432
mitogen-activated protein kinase kinase kinase 10
chr7_-_36096582 1.56 ENSDART00000188507

chr24_-_26302375 1.55 ENSDART00000130696
COP9 signalosome subunit 9
chr24_-_36095526 1.54 ENSDART00000158145

chr15_-_19677511 1.53 ENSDART00000043743
si:dkey-4p15.3
chr10_+_44057177 1.51 ENSDART00000164610
G protein-coupled receptor kinase 3
chr18_-_19484919 1.50 ENSDART00000177690
ENSDART00000184949
lactase-like b
chr3_+_39853788 1.49 ENSDART00000154869
calcium channel, voltage-dependent, T type, alpha 1H subunit a
chr2_+_38881165 1.49 ENSDART00000141850
capping protein regulator and myosin 1 linker 3
chr9_+_22632126 1.49 ENSDART00000139434
ets variant 5a
chr16_-_40727455 1.46 ENSDART00000162331
si:dkey-22o22.2
chr25_-_11088839 1.46 ENSDART00000154748
synaptic vesicle glycoprotein 2Bb
chr17_-_16133249 1.45 ENSDART00000030919
prepronociceptin a
chr1_+_40140498 1.45 ENSDART00000101640
zgc:152658
chr3_-_23406964 1.44 ENSDART00000114723
Rap guanine nucleotide exchange factor (GEF)-like 1
chr7_+_73649686 1.43 ENSDART00000185589
si:dkey-46i9.1
chr3_+_51660158 1.43 ENSDART00000155512
ENSDART00000171764
charged multivesicular body protein 6a
chr9_-_54716363 1.42 ENSDART00000162158
ENSDART00000168430
trafficking protein particle complex 2
chr5_-_26936861 1.42 ENSDART00000191032
HtrA serine peptidase 4
chr16_-_39900665 1.42 ENSDART00000136719
RNA binding motif, single stranded interacting protein
chr21_-_10886709 1.41 ENSDART00000134408
si:dkey-277m11.2
chr18_-_370286 1.39 ENSDART00000162633
si:ch211-79l17.1
chr12_+_4900981 1.39 ENSDART00000171507
CD79b molecule, immunoglobulin-associated beta
chr7_-_12789251 1.39 ENSDART00000052750
ADAMTS-like 3
chr24_-_39826865 1.36 ENSDART00000089232
solute carrier family 12 (potassium/chloride transporter), member 7b
chr5_-_28109416 1.34 ENSDART00000042002
si:ch211-48m9.1
chr1_+_44710955 1.32 ENSDART00000131296
ENSDART00000142187
structure specific recognition protein 1b
chr15_-_26636826 1.29 ENSDART00000087632
solute carrier family 47 (multidrug and toxin extrusion), member 4
chr3_-_55531450 1.26 ENSDART00000155376
testis expressed 2
chr15_-_1003553 1.25 ENSDART00000154195
si:dkey-77f5.6
chr17_-_35076730 1.24 ENSDART00000146590
membrane bound O-acyltransferase domain containing 2a
chr10_+_7182168 1.24 ENSDART00000172766
pleckstrin and Sec7 domain containing 3, like
chr20_+_25563105 1.22 ENSDART00000063100
cytochrome P450, family 2, subfamily P, polypeptide 6
chr12_-_24060358 1.22 ENSDART00000050831
ChaC, cation transport regulator homolog 2 (E. coli)
chr12_-_20373058 1.21 ENSDART00000066382
aquaporin 8a, tandem duplicate 1
chr2_-_5475910 1.20 ENSDART00000100954
ENSDART00000172143
ENSDART00000132496
protein C (inactivator of coagulation factors Va and VIIIa), a
protein C (inactivator of coagulation factors Va and VIIIa), a
chr25_+_22274642 1.20 ENSDART00000127099
nuclear receptor subfamily 2, group E, member 3
chr2_-_5466708 1.18 ENSDART00000136682
protein C (inactivator of coagulation factors Va and VIIIa), a
chr14_+_11762991 1.16 ENSDART00000110004
FERM and PDZ domain containing 3
chr17_-_41798856 1.15 ENSDART00000156031
ENSDART00000192801
ENSDART00000180172
ENSDART00000084745
ENSDART00000175577
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr9_+_35876927 1.15 ENSDART00000138834
mab-21-like 3
chr8_+_8046086 1.15 ENSDART00000163232
ENSDART00000111392
ATP-binding cassette, sub-family D (ALD), member 1
chr17_+_25677458 1.12 ENSDART00000029703
potassium voltage-gated channel, subfamily H (eag-related), member 1a
chr24_-_39858710 1.12 ENSDART00000134251
solute carrier family 12 (potassium/chloride transporter), member 7b
chr19_+_9533008 1.12 ENSDART00000104607
family with sequence similarity 131, member Ba
chr21_-_35082715 1.11 ENSDART00000146454
adrenoceptor beta 2, surface b

Network of associatons between targets according to the STRING database.

First level regulatory network of onecut1+onecutl

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 5.9 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
1.3 4.0 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
1.2 3.7 GO:0035971 peptidyl-histidine dephosphorylation(GO:0035971)
1.1 5.6 GO:0014896 muscle hypertrophy(GO:0014896)
1.1 4.2 GO:0033345 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
1.0 2.9 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.9 2.6 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.7 4.7 GO:0042311 vasodilation(GO:0042311)
0.6 3.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.6 1.9 GO:0030043 actin filament fragmentation(GO:0030043)
0.6 8.0 GO:0010996 response to auditory stimulus(GO:0010996)
0.6 3.1 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.6 3.1 GO:0007624 ultradian rhythm(GO:0007624)
0.6 1.8 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.6 2.3 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.6 2.2 GO:1900120 microglial cell activation(GO:0001774) regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.5 1.6 GO:2000434 regulation of protein neddylation(GO:2000434)
0.4 3.4 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.4 6.5 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.4 5.8 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.3 3.1 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.3 1.0 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.3 4.0 GO:0003315 heart rudiment formation(GO:0003315)
0.3 5.0 GO:0042026 protein refolding(GO:0042026)
0.3 3.2 GO:0034605 cellular response to heat(GO:0034605)
0.2 2.0 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.2 3.1 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.2 3.6 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.2 1.7 GO:0038026 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) reelin-mediated signaling pathway(GO:0038026)
0.2 2.3 GO:0097090 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.2 3.1 GO:0048899 anterior lateral line development(GO:0048899)
0.2 3.3 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.2 1.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.2 1.9 GO:0007608 sensory perception of smell(GO:0007608)
0.2 1.1 GO:0003232 bulbus arteriosus development(GO:0003232)
0.2 2.3 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 3.5 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.2 1.2 GO:0060221 pineal gland development(GO:0021982) retinal rod cell differentiation(GO:0060221)
0.2 4.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2 0.5 GO:0042671 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.2 2.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.2 1.6 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.2 2.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.2 0.8 GO:0007508 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.2 1.9 GO:0007525 somatic muscle development(GO:0007525)
0.2 0.9 GO:0099525 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.2 0.8 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.2 4.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 3.3 GO:0043506 activation of JUN kinase activity(GO:0007257) regulation of JUN kinase activity(GO:0043506) positive regulation of JUN kinase activity(GO:0043507)
0.1 0.8 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.6 GO:0055091 phospholipid homeostasis(GO:0055091)
0.1 1.1 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.1 4.1 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.1 0.7 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.1 6.7 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.1 0.4 GO:2000009 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.1 2.9 GO:0015701 bicarbonate transport(GO:0015701)
0.1 6.5 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 1.1 GO:0021576 hindbrain formation(GO:0021576)
0.1 1.9 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1 1.2 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 2.2 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.1 0.6 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.1 0.9 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.1 2.2 GO:0030183 B cell differentiation(GO:0030183)
0.1 2.5 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 4.7 GO:0007254 JNK cascade(GO:0007254)
0.1 1.5 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 0.7 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.1 4.3 GO:0006986 response to unfolded protein(GO:0006986)
0.1 3.1 GO:0046847 filopodium assembly(GO:0046847)
0.1 1.4 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 8.8 GO:0006475 internal protein amino acid acetylation(GO:0006475) internal peptidyl-lysine acetylation(GO:0018393)
0.1 12.4 GO:0002040 sprouting angiogenesis(GO:0002040)
0.1 2.5 GO:0032526 response to retinoic acid(GO:0032526)
0.1 5.9 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.8 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.4 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.1 2.8 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 3.9 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 3.8 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.1 7.3 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 2.7 GO:0034332 adherens junction organization(GO:0034332)
0.1 1.2 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 1.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 4.2 GO:0036293 response to hypoxia(GO:0001666) response to decreased oxygen levels(GO:0036293)
0.1 0.3 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.1 15.9 GO:0007411 axon guidance(GO:0007411)
0.1 5.9 GO:0051260 protein homooligomerization(GO:0051260)
0.0 5.7 GO:0021782 glial cell development(GO:0021782)
0.0 1.9 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 1.4 GO:0061035 regulation of cartilage development(GO:0061035)
0.0 3.1 GO:0030100 regulation of endocytosis(GO:0030100)
0.0 0.9 GO:0018149 peptide cross-linking(GO:0018149)
0.0 2.1 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 2.5 GO:0008217 regulation of blood pressure(GO:0008217)
0.0 1.9 GO:0035272 exocrine pancreas development(GO:0031017) exocrine system development(GO:0035272)
0.0 2.0 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.6 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.4 GO:0009408 response to heat(GO:0009408)
0.0 1.0 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.0 0.4 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.3 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.5 GO:0097581 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0 0.7 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 1.9 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 2.7 GO:0010506 regulation of autophagy(GO:0010506)
0.0 0.2 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.8 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.7 GO:0048634 regulation of muscle organ development(GO:0048634)
0.0 1.4 GO:0007596 blood coagulation(GO:0007596)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.5 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.5 GO:0045055 regulated exocytosis(GO:0045055)
0.0 0.0 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.0 4.2 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.8 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.6 GO:0010906 regulation of cellular carbohydrate metabolic process(GO:0010675) regulation of glucose metabolic process(GO:0010906)
0.0 1.4 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 1.8 GO:0007409 axonogenesis(GO:0007409)
0.0 0.2 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 0.3 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 1.5 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.2 GO:1900153 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.2 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 0.6 GO:0015914 phospholipid transport(GO:0015914)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.8 GO:0005955 calcineurin complex(GO:0005955)
0.8 2.3 GO:0060077 inhibitory synapse(GO:0060077)
0.7 7.0 GO:0042583 chromaffin granule(GO:0042583)
0.5 2.0 GO:0005588 collagen type V trimer(GO:0005588)
0.4 3.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.4 3.1 GO:0033010 paranodal junction(GO:0033010)
0.3 1.4 GO:0019815 B cell receptor complex(GO:0019815)
0.3 13.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.3 3.0 GO:0033270 paranode region of axon(GO:0033270)
0.3 4.1 GO:0000815 ESCRT III complex(GO:0000815)
0.3 2.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 2.2 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.3 1.9 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 2.9 GO:0044295 axonal growth cone(GO:0044295)
0.2 0.8 GO:0097519 DNA recombinase complex(GO:0097519)
0.2 2.0 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.2 0.8 GO:1990071 TRAPPII protein complex(GO:1990071)
0.2 1.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 6.5 GO:0005861 troponin complex(GO:0005861)
0.1 2.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.6 GO:0008180 COP9 signalosome(GO:0008180)
0.1 3.4 GO:0071565 nBAF complex(GO:0071565)
0.1 6.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 8.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 2.3 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 1.4 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.7 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.1 3.0 GO:0032590 neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590)
0.1 3.1 GO:0016605 PML body(GO:0016605)
0.1 2.0 GO:0035371 microtubule plus-end(GO:0035371)
0.1 1.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 2.8 GO:0043679 axon terminus(GO:0043679)
0.0 2.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 1.8 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 2.7 GO:0016342 catenin complex(GO:0016342)
0.0 2.1 GO:0005902 microvillus(GO:0005902)
0.0 9.5 GO:0030424 axon(GO:0030424)
0.0 2.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 6.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 1.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.5 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 2.3 GO:0014069 postsynaptic density(GO:0014069)
0.0 2.3 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 2.2 GO:0043025 neuronal cell body(GO:0043025)
0.0 2.6 GO:0005581 collagen trimer(GO:0005581)
0.0 1.1 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 1.1 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.5 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 7.6 GO:0043005 neuron projection(GO:0043005)
0.0 1.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 18.2 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.3 GO:0005844 polysome(GO:0005844)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 5.9 GO:0060175 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
1.6 4.8 GO:0048030 disaccharide binding(GO:0048030)
1.2 3.6 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
1.0 2.9 GO:0004351 glutamate decarboxylase activity(GO:0004351)
1.0 5.8 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.9 3.7 GO:0101006 protein histidine phosphatase activity(GO:0101006)
0.8 4.2 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.8 7.8 GO:0016936 galactoside binding(GO:0016936)
0.6 1.9 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.6 2.9 GO:0008046 axon guidance receptor activity(GO:0008046)
0.5 2.9 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.5 7.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.5 8.0 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.5 4.7 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.4 12.0 GO:0051787 misfolded protein binding(GO:0051787)
0.4 3.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.4 3.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.4 2.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.4 3.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.3 1.0 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.3 1.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.3 2.3 GO:0034452 dynactin binding(GO:0034452)
0.3 1.1 GO:0051380 norepinephrine binding(GO:0051380)
0.3 1.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.3 2.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.3 2.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.3 1.8 GO:0099583 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.2 4.0 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.2 3.1 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 1.8 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 3.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 1.5 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 0.8 GO:1990238 double-stranded DNA endodeoxyribonuclease activity(GO:1990238)
0.2 6.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 2.8 GO:0032051 clathrin light chain binding(GO:0032051)
0.2 1.8 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 3.3 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.2 2.7 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.2 2.8 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.2 0.7 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.2 2.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 1.8 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 3.6 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.9 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.2 GO:0015250 water channel activity(GO:0015250)
0.1 6.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 3.4 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 1.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 2.9 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 0.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 1.5 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 2.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 6.5 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.1 1.8 GO:0048495 Roundabout binding(GO:0048495)
0.1 7.0 GO:0042562 hormone binding(GO:0042562)
0.1 1.5 GO:0031628 opioid receptor binding(GO:0031628)
0.1 1.7 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.1 6.7 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 1.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 2.5 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 2.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.7 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 4.0 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 1.3 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.1 2.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.6 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 1.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 1.5 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.8 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.4 GO:0004966 galanin receptor activity(GO:0004966)
0.1 3.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 2.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 2.3 GO:0005548 phospholipid transporter activity(GO:0005548)
0.1 2.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.4 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.3 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 1.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.9 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.5 GO:0043495 protein anchor(GO:0043495)
0.0 1.0 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.5 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.7 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 1.0 GO:0030165 PDZ domain binding(GO:0030165)
0.0 4.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.8 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 1.0 GO:0019003 GDP binding(GO:0019003)
0.0 2.3 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 2.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0051117 ATPase binding(GO:0051117)
0.0 1.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 8.3 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 1.4 GO:0005267 potassium channel activity(GO:0005267)
0.0 1.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 5.6 GO:0008017 microtubule binding(GO:0008017)
0.0 0.5 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 2.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 1.5 GO:0045296 cadherin binding(GO:0045296)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 2.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.2 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 1.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.7 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 1.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 7.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.2 4.7 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.2 2.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.2 6.5 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.1 7.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 2.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 1.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 0.5 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.1 12.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.0 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 2.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 4.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 0.8 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.9 PID RAS PATHWAY Regulation of Ras family activation
0.0 2.4 PID P53 REGULATION PATHWAY p53 pathway
0.0 6.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.4 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.6 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.5 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.5 4.7 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.3 5.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 1.0 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.2 3.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 3.0 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.2 3.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 1.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 5.6 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 7.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 0.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 0.5 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.1 2.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 2.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 2.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.8 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1 2.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 3.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 0.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 2.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.3 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis