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PRJEB1986: zebrafish developmental stages transcriptome

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Results for nrf1

Z-value: 3.86

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Transcription factors associated with nrf1

Gene Symbol Gene ID Gene Info
ENSDARG00000000018 nuclear respiratory factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nrf1dr11_v1_chr4_-_15103646_151036960.734.1e-04Click!

Activity profile of nrf1 motif

Sorted Z-values of nrf1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_41966854 11.38 ENSDART00000055709
hairy-related 2
chr16_-_7379328 11.10 ENSDART00000060447
mediator of RNA polymerase II transcription, subunit 18 homolog (yeast)
chr24_+_42004640 9.73 ENSDART00000171380
DNA topoisomerase I mitochondrial
chr17_-_20167206 9.10 ENSDART00000104874
ENSDART00000191995
prolyl 4-hydroxylase, alpha polypeptide I b
chr20_-_46541834 7.91 ENSDART00000060685
ENSDART00000181720
transmembrane p24 trafficking protein 10
chr10_-_40826657 7.90 ENSDART00000076304
proliferating cell nuclear antigen
chr17_+_24821627 7.75 ENSDART00000112389
WD repeat domain 43
chr6_-_9676108 7.66 ENSDART00000169915
NOP58 ribonucleoprotein homolog (yeast)
chr17_+_37932706 7.59 ENSDART00000075941
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr16_+_40575742 7.27 ENSDART00000161503
cyclin E2
chr22_-_16291041 7.03 ENSDART00000021666
RNA 3'-terminal phosphate cyclase
chr1_+_25178106 6.88 ENSDART00000054265
ENSDART00000141648
meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr22_+_18319230 6.83 ENSDART00000184747
ENSDART00000184649
GATA zinc finger domain containing 2Ab
chr25_+_22320738 6.66 ENSDART00000073566
cytochrome P450, family 11, subfamily A, polypeptide 1
chr1_-_25438737 6.65 ENSDART00000134470
FH2 domain containing 1
chr17_+_53428092 6.45 ENSDART00000192509
serine/arginine-rich splicing factor 10b
chr5_-_24882357 6.36 ENSDART00000127773
ENSDART00000003998
ENSDART00000143851
EWS RNA-binding protein 1b
chr1_-_21563040 6.33 ENSDART00000049572
non-SMC condensin II complex, subunit D3
chr3_+_48473346 6.26 ENSDART00000166294
meteorin, glial cell differentiation regulator-like
chr1_+_260039 6.23 ENSDART00000092584
ENSDART00000111806
centromere protein E
chr24_+_7153628 6.19 ENSDART00000147715
si:dkeyp-101e12.1
chr21_+_18275961 6.12 ENSDART00000019750
WD repeat domain 5
chr23_-_18913032 6.08 ENSDART00000136678
si:ch211-209j10.6
chr11_+_33818179 5.86 ENSDART00000109418
speckle-type POZ protein-like b
chr20_+_48116476 5.79 ENSDART00000043938
translocation associated membrane protein 2
chr14_+_14806851 5.68 ENSDART00000169235
FH2 domain containing 2
chr25_-_12824939 5.68 ENSDART00000169126
ubiquitin-like modifier activating enzyme 2
chr13_-_51903150 5.65 ENSDART00000090644
mitochondrial ribosomal protein L2
chr7_+_26534131 5.63 ENSDART00000173980
si:dkey-62k3.5
chr17_+_37932433 5.62 ENSDART00000185349
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr25_-_31629095 5.60 ENSDART00000170673
ENSDART00000166930
laminin, beta 1a
chr20_-_2725594 5.57 ENSDART00000152120
akirin 2
chr25_+_22319940 5.53 ENSDART00000154065
ENSDART00000153492
ENSDART00000024866
ENSDART00000154376
cytochrome P450, family 11, subfamily A, polypeptide 1
chr7_-_20464133 5.52 ENSDART00000078192
canopy4
chr17_+_20923691 5.50 ENSDART00000122407
cyclin-dependent kinase 1
chr5_+_23913585 5.36 ENSDART00000015401
excision repair cross-complementation group 6-like
chr24_+_35911300 5.31 ENSDART00000129679
ATP-binding cassette, sub-family D (ALD), member 4
chr1_+_53919110 5.31 ENSDART00000020680
nucleoporin 133
chr18_-_21929426 5.27 ENSDART00000132034
ENSDART00000079050
nuclear transport factor 2
chr1_+_21563311 5.25 ENSDART00000147076
ENSDART00000006147
primase and polymerase (DNA-directed)
chr7_-_41881177 5.23 ENSDART00000174258
ENSDART00000018972
zgc:92818
chr15_-_16384184 5.22 ENSDART00000154504
family with sequence similarity 222, member Bb
chr16_-_6205790 5.21 ENSDART00000038495
catenin (cadherin-associated protein), beta 1
chr7_-_50367642 5.19 ENSDART00000134941
protein regulator of cytokinesis 1b
chr16_-_21140097 5.19 ENSDART00000145837
ENSDART00000146500
si:dkey-271j15.3
chr6_-_9695294 5.17 ENSDART00000162728
NOP58 ribonucleoprotein homolog (yeast)
chr3_-_13599482 5.17 ENSDART00000166639
Tu translation elongation factor, mitochondrial
chr23_-_44723102 5.03 ENSDART00000129138
monoacylglycerol O-acyltransferase 3a
chr20_+_25445826 4.98 ENSDART00000012581
phosphoribosylformylglycinamidine synthase
chr25_-_35956344 4.95 ENSDART00000066987
M-phase phosphoprotein 6
chr14_-_9085349 4.92 ENSDART00000054710
polymerase (RNA) I polypeptide D
chr5_+_60847823 4.91 ENSDART00000074426
ligase III, DNA, ATP-dependent
chr12_+_47663419 4.91 ENSDART00000171932
hematopoietically expressed homeobox
chr14_-_26377044 4.89 ENSDART00000022236
empty spiracles homeobox 3
chr16_+_28728347 4.89 ENSDART00000149240
si:dkey-24i24.3
chr20_+_34770197 4.87 ENSDART00000018304
minichromosome maintenance complex component 3
chr7_+_57088920 4.86 ENSDART00000024076
secretory carrier membrane protein 2, like
chr15_+_26933196 4.82 ENSDART00000023842
protein phosphatase, Mg2+/Mn2+ dependent, 1Da
chr6_-_8392104 4.80 ENSDART00000081561
ENSDART00000181178
interleukin enhancer binding factor 3a
chr13_+_25364753 4.76 ENSDART00000027428
conserved helix-loop-helix ubiquitous kinase
chr17_-_29224908 4.74 ENSDART00000156288
si:dkey-28g23.6
chr6_-_19340889 4.63 ENSDART00000181407
MIF4G domain containing a
chr20_-_2725930 4.62 ENSDART00000081643
akirin 2
chr6_+_149405 4.60 ENSDART00000161154
ferredoxin 1-like
chr11_-_26375575 4.59 ENSDART00000079255
UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
chr13_+_159504 4.58 ENSDART00000057248
EWS RNA-binding protein 1b
chr4_-_9909371 4.56 ENSDART00000102656
si:dkey-22l11.6
chr5_+_61459422 4.56 ENSDART00000050902
polymerase (RNA) II (DNA directed) polypeptide J
chr18_-_7448047 4.53 ENSDART00000193213
ENSDART00000131940
ENSDART00000186944
ENSDART00000052803
si:dkey-30c15.10
chr12_-_49168398 4.53 ENSDART00000186608

chr9_+_53276356 4.52 ENSDART00000003310
SRY (sex determining region Y)-box 21b
chr22_-_4989803 4.52 ENSDART00000181359
ENSDART00000125265
ENSDART00000028634
ENSDART00000183294
calcium homeostasis endoplasmic reticulum protein
chr16_+_52847079 4.49 ENSDART00000163151
centrosomal protein 72
chr21_+_25625026 4.49 ENSDART00000134678
ovo-like zinc finger 1b
chr5_+_29803380 4.48 ENSDART00000005263
ENSDART00000137558
ENSDART00000146963
ENSDART00000134900
upstream transcription factor 1, like
chr21_-_4849029 4.48 ENSDART00000168930
ENSDART00000151019
notch 1a
chr21_+_43702016 4.47 ENSDART00000017176
dyskeratosis congenita 1, dyskerin
chr5_+_41793001 4.42 ENSDART00000136439
ENSDART00000190477
ENSDART00000192289
BCL tumor suppressor 7A
chr21_+_17956856 4.36 ENSDART00000080431
dynein, axonemal, intermediate chain 1, paralog 2
chr9_+_32301456 4.26 ENSDART00000078608
ENSDART00000185153
ENSDART00000144947
heat shock 10 protein 1
chr24_+_4978055 4.25 ENSDART00000045813
zic family member 4
chr1_-_25438934 4.25 ENSDART00000111686
FH2 domain containing 1
chr19_-_18127629 4.22 ENSDART00000187722
sorting nexin 10a
chr23_+_29569893 4.21 ENSDART00000078304
leucine zipper and CTNNBIP1 domain containing
chr16_-_42461263 4.19 ENSDART00000109259
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1a
chr1_-_42289704 4.19 ENSDART00000150124
si:ch211-71k14.1
chr22_-_7050 4.18 ENSDART00000127829
ATPase family, AAA domain containing 3
chr21_+_44684577 4.17 ENSDART00000099528
sprouty homolog 4 (Drosophila)
chr25_-_12824656 4.16 ENSDART00000171801
ubiquitin-like modifier activating enzyme 2
chr24_-_7957581 4.15 ENSDART00000145815
thioredoxin domain containing 5
chr10_+_31244619 4.15 ENSDART00000145562
ENSDART00000184412
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr23_+_10805188 4.14 ENSDART00000035693
protein phosphatase 4, regulatory subunit 2a
chr5_+_1493767 4.14 ENSDART00000022132
HAUS augmin-like complex, subunit 4
chr15_-_14884332 4.12 ENSDART00000165237
si:ch211-24o8.4
chr12_-_34435604 4.12 ENSDART00000115088
baculoviral IAP repeat containing 5a
chr5_+_36666715 4.12 ENSDART00000097686
zgc:153990
chr22_+_18319666 4.11 ENSDART00000033103
GATA zinc finger domain containing 2Ab
chr11_+_31236001 4.10 ENSDART00000129393
tRNA methyltransferase 1
chr4_-_25858620 4.08 ENSDART00000128968
nuclear receptor subfamily 2, group C, member 1
chr19_-_18127808 4.08 ENSDART00000108627
sorting nexin 10a
chr24_+_4977862 4.06 ENSDART00000114537
zic family member 4
chr18_+_46382484 4.04 ENSDART00000024202
ENSDART00000142790
dynein assembly factor with WDR repeat domains 1
chr16_-_32221312 4.02 ENSDART00000112348
calcium homeostasis modulator family member 5, tandem duplicate 1
chr4_-_11024767 3.95 ENSDART00000067261
ENSDART00000167631
transmembrane and tetratricopeptide repeat containing 2a
chr25_-_35296165 3.95 ENSDART00000018107
Fanconi anemia, complementation group F
chr21_+_15601100 3.95 ENSDART00000180558
ENSDART00000145454
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b
chr19_+_24891747 3.94 ENSDART00000132209
ENSDART00000193610
EYA transcriptional coactivator and phosphatase 3
chr14_-_21123325 3.94 ENSDART00000180889
ENSDART00000188539
si:dkey-74k8.4
chr5_+_50869091 3.90 ENSDART00000083294
nucleolar protein 6 (RNA-associated)
chr6_+_56141852 3.89 ENSDART00000149665
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr6_-_19341184 3.89 ENSDART00000168236
ENSDART00000167674
MIF4G domain containing a
chr8_-_14239023 3.88 ENSDART00000090371
SIN3 transcription regulator family member B
chr17_+_28706946 3.87 ENSDART00000126967
striatin, calmodulin binding protein 3
chr2_+_25839650 3.85 ENSDART00000134077
ENSDART00000140804
eukaryotic translation initiation factor 5A2
chr20_+_50015470 3.82 ENSDART00000189319
ribosomal oxygenase 1
chr5_+_19933356 3.80 ENSDART00000088819
ankyrin repeat domain 13A
chr2_+_29996650 3.79 ENSDART00000138050
ENSDART00000141026
RNA binding motif protein 33b
chr24_-_38657683 3.77 ENSDART00000154843
si:ch1073-164k15.3
chr13_-_35844961 3.77 ENSDART00000171371
mitogen-activated protein kinase kinase kinase 4
chr25_-_17852944 3.75 ENSDART00000155169
si:ch211-176l24.4
chr21_+_18274825 3.73 ENSDART00000144322
ENSDART00000147768
WD repeat domain 5
chr19_-_48039400 3.69 ENSDART00000166748
ENSDART00000165921
colony stimulating factor 3 (granulocyte) b
chr16_-_4769877 3.66 ENSDART00000149421
ENSDART00000054078
replication protein A2
chr22_-_24285432 3.64 ENSDART00000164083
si:ch211-117l17.4
chr16_-_4770233 3.63 ENSDART00000193228
replication protein A2
chr13_+_25364324 3.62 ENSDART00000187471
conserved helix-loop-helix ubiquitous kinase
chr14_+_24277556 3.62 ENSDART00000122660
heterogeneous nuclear ribonucleoprotein A0a
chr10_+_19026988 3.61 ENSDART00000137456
immunoglobulin superfamily, member 9a
chr22_-_15704704 3.59 ENSDART00000017838
ENSDART00000130238
scaffold attachment factor B
chr22_+_25931782 3.59 ENSDART00000157842
DnaJ (Hsp40) homolog, subfamily A, member 3B
chr15_+_24549054 3.57 ENSDART00000155900
PHD finger protein 12b
chr7_+_57089354 3.56 ENSDART00000140702
secretory carrier membrane protein 2, like
chr22_+_336256 3.56 ENSDART00000019155
B-cell translocation gene 2
chr13_+_5004924 3.56 ENSDART00000056295
ENSDART00000130379
prosaposin
chr25_+_2776511 3.54 ENSDART00000115280
neogenin 1b
chr7_-_50367326 3.53 ENSDART00000141926
protein regulator of cytokinesis 1b
chr8_+_13064750 3.52 ENSDART00000039878
SAP30 binding protein
chr14_-_1355544 3.51 ENSDART00000060417
centrin 4
chr18_-_50799510 3.50 ENSDART00000174373
transaldolase 1
chr21_-_18275226 3.50 ENSDART00000126672
ENSDART00000135239
bromodomain containing 3a
chr17_-_53348486 3.49 ENSDART00000161183

chr13_+_15701849 3.48 ENSDART00000003517
tRNA methyltransferase 61A
chr19_+_20787179 3.47 ENSDART00000193204
ADNP homeobox 2b
chr16_+_4770266 3.46 ENSDART00000038036
ubiquitin protein ligase E3D
chr23_+_31815423 3.46 ENSDART00000075730
ENSDART00000075726
v-myb avian myeloblastosis viral oncogene homolog
chr22_+_37631034 3.46 ENSDART00000159016
ENSDART00000193346
proteasome 26S subunit, non-ATPase 1
chr19_-_35450661 3.45 ENSDART00000113574
ENSDART00000136895
anillin, actin binding protein
chr5_-_33281046 3.43 ENSDART00000051344
ENSDART00000138116
surfeit 6
chr1_-_44484 3.43 ENSDART00000171547
ENSDART00000164075
ENSDART00000168091
transmembrane protein 39A
chr25_-_35101673 3.41 ENSDART00000140864
zgc:162611
chr13_-_36621926 3.41 ENSDART00000057155
cyclin-dependent kinase inhibitor 3
chr15_+_16886196 3.40 ENSDART00000139296
ENSDART00000049196
glycerophosphodiester phosphodiesterase domain containing 1
chr6_+_48862 3.38 ENSDART00000082954
methyl-CpG binding domain protein 5
chr2_+_30182431 3.36 ENSDART00000004903
retinol dehydrogenase 10b
chr20_-_54245256 3.36 ENSDART00000170482
PRP39 pre-mRNA processing factor 39 homolog (yeast)
chr11_-_12233 3.35 ENSDART00000173352
ENSDART00000173009
ENSDART00000102293
melanocyte proliferating gene 1
chr11_-_309420 3.35 ENSDART00000173185
POC1 centriolar protein A
chr2_+_25839193 3.35 ENSDART00000078634
eukaryotic translation initiation factor 5A2
chr13_+_15702142 3.32 ENSDART00000135960
tRNA methyltransferase 61A
chr3_+_43086548 3.29 ENSDART00000163579
si:dkey-43p13.5
chr7_+_39738505 3.28 ENSDART00000004365
transcriptional adaptor 2B
chr25_+_7532627 3.28 ENSDART00000187660
phosphatidylserine synthase 2
chr19_-_30800004 3.27 ENSDART00000128560
ENSDART00000045504
ENSDART00000125893
tRNA isopentenyltransferase 1
chr5_-_32445835 3.25 ENSDART00000170919
neuronal calcium sensor 1a
chr12_+_10443785 3.25 ENSDART00000029133
SNU13 homolog, small nuclear ribonucleoprotein b (U4/U6.U5)
chr23_-_493384 3.25 ENSDART00000128433
histocompatibility (minor) 13
chr10_-_33265566 3.23 ENSDART00000063642
transducin (beta)-like 2
chr22_-_25078650 3.22 ENSDART00000131811
ENSDART00000141546
lysine acetyltransferase 14
chr10_+_44984946 3.21 ENSDART00000182520
H2A histone family, member Vb
chr16_-_7793457 3.20 ENSDART00000113483
tripartite motif containing 71, E3 ubiquitin protein ligase
chr25_-_35101396 3.20 ENSDART00000138865
zgc:162611
chr15_+_9861973 3.19 ENSDART00000170945
si:dkey-13m3.2
chr11_-_36450770 3.19 ENSDART00000128889
zinc finger and BTB domain containing 40
chr16_-_30563129 3.17 ENSDART00000191716
lamin A
chr5_-_41142467 3.16 ENSDART00000129415
zinc finger RNA binding protein
chr21_-_34032650 3.16 ENSDART00000138575
ENSDART00000047515
ring finger protein 145b
chr1_-_39983730 3.15 ENSDART00000160066
inhibitor of growth family, member 2
chr4_+_966061 3.14 ENSDART00000122535
RNA polymerase II associated protein 3
chr15_-_28587147 3.14 ENSDART00000156049
slingshot protein phosphatase 2a
chr19_-_25693728 3.12 ENSDART00000136187
biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino
chr5_-_69716501 3.10 ENSDART00000158956
MOB kinase activator 1A
chr24_-_24168475 3.10 ENSDART00000139369
ENSDART00000080671
eukaryotic translation initiation factor 1A, X-linked, b
chr3_+_15736811 3.09 ENSDART00000080075
prohibitin
chr23_+_26079467 3.09 ENSDART00000129617
ATPase H+ transporting accessory protein 1b
chr25_+_30460378 3.07 ENSDART00000016310
BTG3 associated nuclear protein
chr19_-_42588510 3.05 ENSDART00000102583
synaptotagmin-like 1
chr18_-_7097403 3.05 ENSDART00000003748
cilia and flagella associated protein 161
chr20_-_51547464 3.03 ENSDART00000099486
dispatched homolog 1 (Drosophila)
chr5_-_19932621 3.03 ENSDART00000088881
G protein-coupled receptor kinase interacting ArfGAP 2a
chr3_+_26342768 3.00 ENSDART00000163832
si:ch211-156b7.4
chr11_+_12744575 2.99 ENSDART00000131059
ENSDART00000081335
ENSDART00000142481
retinoblastoma binding protein 4, like
chr21_+_249970 2.99 ENSDART00000169026
Janus kinase 2a
chr14_-_26411918 2.98 ENSDART00000020582
transmembrane p24 trafficking protein 9
chr3_+_38540411 2.96 ENSDART00000154943
si:dkey-7f16.3
chr22_+_15343953 2.95 ENSDART00000045682
ribosomal RNA processing 36
chr12_+_27022517 2.95 ENSDART00000152975
male-specific lethal 1 homolog b (Drosophila)
chr21_+_37090585 2.94 ENSDART00000182971
zinc finger protein 346
chr22_+_37631234 2.91 ENSDART00000007346
proteasome 26S subunit, non-ATPase 1
chr3_-_37082618 2.91 ENSDART00000026701
ENSDART00000110716
tubulin, gamma 1
chr8_-_51954562 2.90 ENSDART00000132527
ENSDART00000057315
centrosomal protein 78

Network of associatons between targets according to the STRING database.

First level regulatory network of nrf1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
2.4 12.2 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
2.0 7.9 GO:0006272 leading strand elongation(GO:0006272)
1.9 11.4 GO:0007405 neuroblast proliferation(GO:0007405)
1.8 5.5 GO:1903392 epicardial cell to mesenchymal cell transition(GO:0003347) negative regulation of adherens junction organization(GO:1903392)
1.7 5.2 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
1.7 5.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
1.7 10.1 GO:0055016 hypochord development(GO:0055016)
1.7 8.4 GO:0007252 I-kappaB phosphorylation(GO:0007252)
1.7 8.3 GO:0070986 left/right axis specification(GO:0070986)
1.6 6.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
1.5 4.5 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
1.5 10.3 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
1.4 4.1 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
1.4 4.1 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
1.3 9.2 GO:0045901 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
1.3 3.9 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
1.2 5.0 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
1.2 7.4 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
1.2 8.5 GO:0032185 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
1.2 8.3 GO:0021534 cell proliferation in hindbrain(GO:0021534)
1.1 5.7 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
1.1 5.5 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
1.1 3.2 GO:0010586 miRNA metabolic process(GO:0010586)
1.1 6.3 GO:0090342 regulation of cell aging(GO:0090342)
1.1 4.2 GO:0070920 regulation of production of small RNA involved in gene silencing by RNA(GO:0070920) regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798)
1.0 2.0 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
1.0 3.0 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
1.0 2.9 GO:0000212 meiotic spindle organization(GO:0000212)
1.0 3.8 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.9 10.0 GO:0000022 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.9 3.5 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.9 2.6 GO:1905048 regulation of metallopeptidase activity(GO:1905048)
0.9 2.6 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.8 3.4 GO:0070291 N-acylethanolamine metabolic process(GO:0070291)
0.8 2.5 GO:0009193 ribonucleoside diphosphate catabolic process(GO:0009191) pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.8 4.9 GO:1902975 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.8 5.6 GO:0031643 positive regulation of myelination(GO:0031643)
0.8 5.3 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.7 2.2 GO:0072526 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.7 3.5 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.7 4.8 GO:0046294 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.7 6.1 GO:2000758 positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.7 4.6 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.6 2.5 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.6 10.5 GO:0034629 cellular protein complex localization(GO:0034629)
0.6 3.1 GO:1901207 regulation of heart looping(GO:1901207)
0.6 2.5 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.6 11.7 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.6 6.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.6 5.8 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.6 3.5 GO:0045658 regulation of granulocyte differentiation(GO:0030852) regulation of neutrophil differentiation(GO:0045658)
0.6 3.4 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.5 3.7 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.5 2.1 GO:0006404 RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
0.5 4.6 GO:1901099 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.5 5.6 GO:0006611 protein export from nucleus(GO:0006611)
0.5 5.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.5 1.5 GO:0051958 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.5 2.5 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.5 5.0 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.5 6.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.5 2.4 GO:0045056 transcytosis(GO:0045056)
0.5 1.4 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.5 6.1 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.5 2.3 GO:0060760 positive regulation of cytokine-mediated signaling pathway(GO:0001961) positive regulation of response to cytokine stimulus(GO:0060760)
0.5 3.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.5 2.3 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.4 2.7 GO:0003342 proepicardium development(GO:0003342) septum transversum development(GO:0003343) determination of intestine left/right asymmetry(GO:0071908)
0.4 1.8 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.4 13.2 GO:0001569 patterning of blood vessels(GO:0001569)
0.4 2.5 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.4 3.9 GO:0043931 ossification involved in bone maturation(GO:0043931) bone maturation(GO:0070977)
0.4 1.9 GO:0071763 nuclear membrane organization(GO:0071763)
0.4 2.3 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.4 2.3 GO:0006013 mannose metabolic process(GO:0006013)
0.4 6.1 GO:0006265 DNA topological change(GO:0006265)
0.4 3.2 GO:0006465 signal peptide processing(GO:0006465)
0.4 8.8 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.3 1.6 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.3 1.6 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.3 8.5 GO:0006446 regulation of translational initiation(GO:0006446)
0.3 9.1 GO:0016925 protein sumoylation(GO:0016925)
0.3 0.9 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.3 2.1 GO:0070285 pigment cell development(GO:0070285)
0.3 1.5 GO:0060544 regulation of necrotic cell death(GO:0010939) regulation of necroptotic process(GO:0060544)
0.3 5.4 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.3 9.6 GO:0030488 tRNA methylation(GO:0030488)
0.3 2.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.3 2.7 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.3 8.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.3 2.9 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.3 2.6 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.3 4.0 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.3 2.2 GO:0051013 microtubule severing(GO:0051013)
0.3 0.8 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.3 0.8 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.3 3.4 GO:0042572 retinol metabolic process(GO:0042572)
0.3 2.5 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.3 1.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.2 2.0 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.2 1.2 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.2 1.7 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.2 3.0 GO:0042694 muscle cell fate specification(GO:0042694)
0.2 1.8 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.2 1.1 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.2 1.8 GO:0008343 adult feeding behavior(GO:0008343)
0.2 3.7 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.2 3.5 GO:0051865 protein autoubiquitination(GO:0051865)
0.2 1.1 GO:0072103 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.2 0.8 GO:0090085 regulation of protein deubiquitination(GO:0090085)
0.2 4.6 GO:0009408 response to heat(GO:0009408)
0.2 1.3 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.2 0.4 GO:0045649 regulation of macrophage differentiation(GO:0045649)
0.2 2.5 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.2 6.3 GO:0006289 nucleotide-excision repair(GO:0006289)
0.2 1.6 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2 1.0 GO:1903426 regulation of reactive oxygen species biosynthetic process(GO:1903426)
0.2 4.1 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 4.9 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.2 1.5 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168)
0.2 2.0 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.2 1.3 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.2 4.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 8.4 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.2 5.7 GO:0032543 mitochondrial translation(GO:0032543)
0.2 9.0 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.2 12.4 GO:0034504 protein localization to nucleus(GO:0034504)
0.2 6.0 GO:0060872 semicircular canal development(GO:0060872)
0.2 3.8 GO:0043249 erythrocyte maturation(GO:0043249)
0.2 2.2 GO:0070189 kynurenine metabolic process(GO:0070189)
0.2 1.6 GO:0030104 water homeostasis(GO:0030104)
0.2 3.9 GO:0036297 interstrand cross-link repair(GO:0036297)
0.2 2.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 3.7 GO:0016180 snRNA processing(GO:0016180)
0.2 6.1 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.1 5.0 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.1 10.2 GO:0045089 positive regulation of innate immune response(GO:0045089)
0.1 35.1 GO:0042254 ribosome biogenesis(GO:0042254)
0.1 1.3 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.1 2.9 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 3.0 GO:0046427 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.1 2.7 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.1 1.9 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 6.3 GO:0055072 iron ion homeostasis(GO:0055072)
0.1 2.0 GO:0002574 thrombocyte differentiation(GO:0002574)
0.1 0.7 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 11.0 GO:0007030 Golgi organization(GO:0007030)
0.1 2.6 GO:0060030 dorsal convergence(GO:0060030)
0.1 2.2 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.1 1.0 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 2.7 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.1 0.7 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.2 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.1 0.6 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 3.4 GO:0007050 cell cycle arrest(GO:0007050)
0.1 4.2 GO:0043277 apoptotic cell clearance(GO:0043277)
0.1 5.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 4.1 GO:0043523 regulation of neuron apoptotic process(GO:0043523)
0.1 3.7 GO:0021954 central nervous system neuron development(GO:0021954)
0.1 1.4 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 2.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 21.1 GO:0006470 protein dephosphorylation(GO:0006470)
0.1 1.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 4.2 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.1 1.5 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 2.0 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 3.3 GO:0006400 tRNA modification(GO:0006400)
0.1 2.0 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.1 1.3 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 3.0 GO:0016573 histone acetylation(GO:0016573)
0.1 1.1 GO:0030878 thyroid gland development(GO:0030878)
0.1 0.4 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 1.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 1.5 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.1 0.9 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 3.6 GO:0050684 regulation of mRNA processing(GO:0050684)
0.1 2.9 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.1 2.5 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 0.6 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 3.6 GO:0051607 defense response to virus(GO:0051607)
0.1 2.9 GO:0048484 enteric nervous system development(GO:0048484)
0.1 4.8 GO:0031101 fin regeneration(GO:0031101)
0.1 0.3 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.1 1.9 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 1.3 GO:0035082 axoneme assembly(GO:0035082)
0.0 1.1 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.4 GO:0030719 P granule organization(GO:0030719)
0.0 0.7 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.0 0.3 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.5 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 1.1 GO:0071230 positive regulation of TOR signaling(GO:0032008) cellular response to amino acid stimulus(GO:0071230)
0.0 1.1 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 1.4 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 2.8 GO:0007098 centrosome cycle(GO:0007098)
0.0 1.3 GO:0007340 acrosome reaction(GO:0007340)
0.0 4.0 GO:0009913 epidermal cell differentiation(GO:0009913)
0.0 3.0 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 3.2 GO:0006413 translational initiation(GO:0006413)
0.0 0.6 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 1.5 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.4 GO:0045444 fat cell differentiation(GO:0045444)
0.0 1.6 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.5 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 3.6 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 0.4 GO:0015800 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0 0.4 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.2 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.6 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.5 GO:0043248 proteasome assembly(GO:0043248)
0.0 3.7 GO:0042176 regulation of protein catabolic process(GO:0042176)
0.0 0.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.4 GO:0070828 heterochromatin organization(GO:0070828)
0.0 0.7 GO:0048634 regulation of muscle organ development(GO:0048634)
0.0 0.9 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 2.5 GO:0001756 somitogenesis(GO:0001756)
0.0 1.6 GO:0030100 regulation of endocytosis(GO:0030100)
0.0 1.4 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.7 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 3.3 GO:0051604 protein maturation(GO:0051604)
0.0 9.9 GO:0006396 RNA processing(GO:0006396)
0.0 0.9 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.0 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 1.2 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 2.8 GO:0007059 chromosome segregation(GO:0007059)
0.0 8.2 GO:0006325 chromatin organization(GO:0006325)
0.0 4.1 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.0 1.7 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 1.0 GO:0007265 Ras protein signal transduction(GO:0007265)
0.0 0.4 GO:0034599 cellular response to oxidative stress(GO:0034599)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 1.8 GO:0050770 regulation of axonogenesis(GO:0050770)
0.0 0.2 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.6 GO:0044344 fibroblast growth factor receptor signaling pathway(GO:0008543) cellular response to fibroblast growth factor stimulus(GO:0044344) response to fibroblast growth factor(GO:0071774)
0.0 0.5 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 16.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
2.5 10.0 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
2.5 9.8 GO:0031510 SUMO activating enzyme complex(GO:0031510)
2.1 6.4 GO:0034515 proteasome storage granule(GO:0034515)
1.8 12.8 GO:0070847 core mediator complex(GO:0070847)
1.4 8.4 GO:0008385 IkappaB kinase complex(GO:0008385)
1.4 4.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
1.4 6.8 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
1.3 3.9 GO:0034456 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
1.2 8.5 GO:0005662 DNA replication factor A complex(GO:0005662)
1.2 8.5 GO:0005826 actomyosin contractile ring(GO:0005826)
1.1 4.5 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.9 5.2 GO:0005913 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.8 3.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.7 5.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.7 2.2 GO:0008352 katanin complex(GO:0008352)
0.7 10.8 GO:0071564 npBAF complex(GO:0071564)
0.7 8.7 GO:1990023 mitotic spindle midzone(GO:1990023)
0.7 4.7 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.7 5.2 GO:0072487 MSL complex(GO:0072487)
0.6 2.6 GO:1990909 Wnt signalosome(GO:1990909)
0.6 10.6 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.6 5.3 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.6 10.9 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.6 6.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.5 1.6 GO:0005828 kinetochore microtubule(GO:0005828)
0.5 1.6 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.5 10.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.5 3.1 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.5 1.5 GO:0097361 CIA complex(GO:0097361)
0.5 5.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.5 4.6 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.5 4.1 GO:0070652 HAUS complex(GO:0070652)
0.4 2.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.4 4.4 GO:0036157 outer dynein arm(GO:0036157)
0.4 2.5 GO:0071818 BAT3 complex(GO:0071818)
0.4 3.9 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.4 3.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.3 3.4 GO:0071565 nBAF complex(GO:0071565)
0.3 7.5 GO:0070822 Sin3-type complex(GO:0070822)
0.3 2.3 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.3 7.5 GO:0071004 U2-type prespliceosome(GO:0071004) prespliceosome(GO:0071010)
0.3 2.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.3 2.5 GO:0001772 immunological synapse(GO:0001772)
0.3 12.4 GO:0005643 nuclear pore(GO:0005643)
0.3 1.5 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.3 1.6 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.3 4.8 GO:0070461 SAGA-type complex(GO:0070461)
0.3 2.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.3 15.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.3 1.5 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.3 5.6 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.3 3.8 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.2 3.7 GO:0044545 NSL complex(GO:0044545)
0.2 3.5 GO:0016363 nuclear matrix(GO:0016363)
0.2 2.0 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.2 1.1 GO:0055087 Ski complex(GO:0055087)
0.2 4.1 GO:0005876 spindle microtubule(GO:0005876)
0.2 1.9 GO:0016272 prefoldin complex(GO:0016272)
0.2 3.0 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 14.5 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.2 3.0 GO:0045180 basal cortex(GO:0045180)
0.2 13.4 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.2 2.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 5.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 3.1 GO:0042555 MCM complex(GO:0042555)
0.2 0.6 GO:0010369 chromocenter(GO:0010369)
0.2 2.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 0.9 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.2 8.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 1.1 GO:0071986 Ragulator complex(GO:0071986)
0.2 3.7 GO:0032039 integrator complex(GO:0032039)
0.2 11.8 GO:0030684 preribosome(GO:0030684)
0.2 7.0 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2 2.6 GO:0036038 MKS complex(GO:0036038)
0.2 1.3 GO:0034464 BBSome(GO:0034464)
0.2 2.7 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 1.3 GO:0032797 SMN complex(GO:0032797)
0.2 1.3 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.2 1.7 GO:0030904 retromer complex(GO:0030904)
0.1 2.1 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.1 3.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 2.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 2.0 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 5.3 GO:0005657 replication fork(GO:0005657)
0.1 3.0 GO:0005844 polysome(GO:0005844)
0.1 0.5 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 10.2 GO:0016607 nuclear speck(GO:0016607)
0.1 1.0 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 2.8 GO:0043204 perikaryon(GO:0043204)
0.1 1.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 2.3 GO:0000781 chromosome, telomeric region(GO:0000781)
0.1 1.2 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.1 0.4 GO:0071546 pi-body(GO:0071546)
0.0 13.8 GO:0000785 chromatin(GO:0000785)
0.0 0.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 10.0 GO:0005730 nucleolus(GO:0005730)
0.0 8.2 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.8 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 2.9 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.8 GO:0044447 axoneme part(GO:0044447)
0.0 2.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.3 GO:0031514 motile cilium(GO:0031514)
0.0 5.9 GO:0010008 endosome membrane(GO:0010008)
0.0 4.0 GO:0005635 nuclear envelope(GO:0005635)
0.0 9.0 GO:0019866 mitochondrial inner membrane(GO:0005743) organelle inner membrane(GO:0019866)
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 0.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.0 2.4 GO:0005774 vacuolar membrane(GO:0005774)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.5 GO:0030117 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 21.9 GO:0005829 cytosol(GO:0005829)
0.0 0.6 GO:0016605 PML body(GO:0016605)
0.0 2.1 GO:0016459 myosin complex(GO:0016459)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.8 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 12.6 GO:0044428 nuclear part(GO:0044428)
0.0 46.2 GO:0005634 nucleus(GO:0005634)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.2 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
2.9 11.4 GO:0033149 FFAT motif binding(GO:0033149)
2.5 9.8 GO:0019948 SUMO activating enzyme activity(GO:0019948)
2.4 11.9 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
2.1 8.4 GO:0008384 IkappaB kinase activity(GO:0008384)
1.4 6.8 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
1.0 4.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
1.0 1.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.9 8.5 GO:0008494 translation activator activity(GO:0008494)
0.9 10.9 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.9 5.4 GO:0015616 DNA translocase activity(GO:0015616)
0.8 2.3 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.7 2.2 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.7 2.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.6 1.9 GO:0000035 acyl binding(GO:0000035)
0.6 3.9 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.6 2.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.6 12.8 GO:0030515 snoRNA binding(GO:0030515)
0.6 2.5 GO:1990931 RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.6 4.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.6 16.5 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.6 8.8 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.6 3.5 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.6 5.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.6 5.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.6 5.0 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.6 5.5 GO:0030332 cyclin binding(GO:0030332)
0.5 5.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.5 2.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.5 6.0 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.5 1.6 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.5 2.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.5 2.6 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.5 5.0 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.5 2.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.5 1.5 GO:0008518 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.5 2.5 GO:0019863 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.5 2.7 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.4 2.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.4 1.7 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.4 1.2 GO:0036310 annealing helicase activity(GO:0036310)
0.4 3.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.4 1.6 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.4 1.5 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.4 1.1 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.4 4.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.4 5.0 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.3 1.7 GO:0008097 5S rRNA binding(GO:0008097)
0.3 3.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.3 6.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.3 4.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.3 3.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.3 0.9 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.3 3.7 GO:0019238 cyclohydrolase activity(GO:0019238)
0.3 10.8 GO:0035064 methylated histone binding(GO:0035064)
0.3 17.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.3 2.6 GO:0035198 miRNA binding(GO:0035198)
0.3 2.8 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.3 1.6 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.3 3.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.3 2.0 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 4.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.2 4.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.2 6.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 3.8 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.2 2.9 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.2 9.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 1.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 2.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 4.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 3.0 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.2 3.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 1.5 GO:0051219 protein phosphorylated amino acid binding(GO:0045309) phosphoprotein binding(GO:0051219)
0.2 2.6 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.2 1.6 GO:0043515 kinetochore binding(GO:0043515)
0.2 4.5 GO:0005112 Notch binding(GO:0005112)
0.2 2.7 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.2 0.5 GO:1990715 mRNA CDS binding(GO:1990715)
0.2 3.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.2 2.6 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.2 6.7 GO:0031072 heat shock protein binding(GO:0031072)
0.2 4.7 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.2 2.5 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.2 1.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 2.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 2.5 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 9.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 5.1 GO:0051087 chaperone binding(GO:0051087)
0.1 0.7 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 7.2 GO:0005178 integrin binding(GO:0005178)
0.1 16.6 GO:0042393 histone binding(GO:0042393)
0.1 51.3 GO:0003712 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.1 4.2 GO:0008013 beta-catenin binding(GO:0008013)
0.1 2.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.8 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.3 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 2.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 4.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.4 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.1 1.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 2.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 2.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 7.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 3.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 6.6 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.1 4.8 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.1 0.8 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 2.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.9 GO:0019894 kinesin binding(GO:0019894)
0.1 1.7 GO:0008143 poly(A) binding(GO:0008143)
0.1 0.7 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 1.0 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 14.7 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 0.6 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 6.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 1.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.6 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 1.8 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 5.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.3 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 7.1 GO:0019208 phosphatase regulator activity(GO:0019208)
0.1 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 1.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 2.6 GO:0019843 rRNA binding(GO:0019843)
0.1 2.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.4 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 0.4 GO:0034584 piRNA binding(GO:0034584)
0.1 0.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.5 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 10.5 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 1.8 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 42.7 GO:0003723 RNA binding(GO:0003723)
0.0 1.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.1 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 2.3 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.6 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 1.4 GO:0098632 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.7 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 1.2 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.8 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.0 0.4 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.9 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.9 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.4 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 1.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.3 GO:0008134 transcription factor binding(GO:0008134)
0.0 0.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 1.7 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.6 GO:0016208 AMP binding(GO:0016208)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 3.8 GO:0003682 chromatin binding(GO:0003682)
0.0 1.4 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 51.4 GO:0003676 nucleic acid binding(GO:0003676)
0.0 0.5 GO:0019003 GDP binding(GO:0019003)
0.0 1.7 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.0 2.6 GO:0005125 cytokine activity(GO:0005125)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 10.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.5 5.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.4 12.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.4 11.8 PID BARD1 PATHWAY BARD1 signaling events
0.4 16.2 PID PLK1 PATHWAY PLK1 signaling events
0.3 5.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.3 8.5 PID ATR PATHWAY ATR signaling pathway
0.2 3.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 2.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.2 3.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.2 6.8 PID P53 REGULATION PATHWAY p53 pathway
0.2 8.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.2 5.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 3.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 1.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 4.9 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 6.2 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.1 4.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 2.4 PID ARF 3PATHWAY Arf1 pathway
0.1 2.3 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.1 2.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 3.9 PID E2F PATHWAY E2F transcription factor network
0.1 2.8 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.1 1.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 1.1 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 2.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.4 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.8 PID P75 NTR PATHWAY p75(NTR)-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
1.4 12.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
1.3 15.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.9 8.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.9 5.5 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.7 3.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.5 8.4 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.5 2.3 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.4 4.9 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.4 10.0 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.4 5.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.4 4.9 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.3 4.9 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.3 2.9 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.3 8.2 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.3 10.7 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.2 1.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.2 1.5 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.2 4.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 3.9 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.2 4.5 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.2 15.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 6.1 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.2 6.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 11.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2 3.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 4.2 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 3.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 7.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 0.5 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 2.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.1 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 2.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 2.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 0.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 2.9 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 1.1 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1 1.9 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 1.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 5.6 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.1 11.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 5.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 1.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 0.6 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 1.1 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.1 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 2.6 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 2.9 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 0.7 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.6 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA