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PRJEB1986: zebrafish developmental stages transcriptome

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Results for nr6a1a

Z-value: 1.64

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Transcription factors associated with nr6a1a

Gene Symbol Gene ID Gene Info
ENSDARG00000101508 nuclear receptor subfamily 6, group A, member 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr6a1adr11_v1_chr8_-_53044300_53044300-0.624.2e-03Click!

Activity profile of nr6a1a motif

Sorted Z-values of nr6a1a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_22188117 9.29 ENSDART00000132890
crystallin, gamma M2d17
chr19_-_5135345 8.91 ENSDART00000151787
guanine nucleotide binding protein (G protein), beta polypeptide 3b
chr10_-_11383900 8.14 ENSDART00000101045
placenta-specific 8, tandem duplicate 1
chr2_-_37210397 6.55 ENSDART00000084938
apolipoprotein Da, duplicate 1
chr3_+_39540014 6.20 ENSDART00000074848
zgc:165423
chr3_+_13469704 6.05 ENSDART00000166806
zgc:77748
chr5_-_50992690 4.54 ENSDART00000149553
ENSDART00000097460
ENSDART00000192021
3-hydroxy-3-methylglutaryl-CoA reductase a
chr9_-_44939104 4.44 ENSDART00000192903
villin 1
chr14_+_32838110 4.26 ENSDART00000158077
arrestin 3b, retinal (X-arrestin)
chr12_+_34896956 4.10 ENSDART00000055415
peripherin 2a (retinal degeneration, slow)
chr25_+_14092871 4.03 ENSDART00000067239
guanylate cyclase activator 1g
chr14_-_33454595 4.01 ENSDART00000109615
ENSDART00000173267
ENSDART00000185737
ENSDART00000190989
transmembrane protein 255A
chr4_+_6643421 3.82 ENSDART00000099462
G protein-coupled receptor 85
chr25_+_33939728 3.77 ENSDART00000148537
RAR-related orphan receptor A, paralog a
chr19_-_703898 3.58 ENSDART00000181096
ENSDART00000121462
solute carrier family 6 (neutral amino acid transporter), member 19a, tandem duplicate 2
chr17_+_25414033 3.55 ENSDART00000001691
L-threonine dehydrogenase 2
chr8_+_44703864 3.53 ENSDART00000016225
steroidogenic acute regulatory protein
chr5_-_9090178 3.47 ENSDART00000091472
potassium channel, subfamily V, member 2b
chr10_-_17284055 3.44 ENSDART00000167464
G protein subunit alpha z
chr25_+_3326885 3.33 ENSDART00000104866
lactate dehydrogenase Bb
chr1_-_50859053 3.29 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
chr17_+_18117358 3.20 ENSDART00000144894
B cell CLL/lymphoma 11Ba
chr6_-_47246948 3.13 ENSDART00000162435
glutamate receptor, metabotropic 4
chr6_+_41099787 3.08 ENSDART00000186884
FK506 binding protein 5
chr12_+_46605600 3.05 ENSDART00000123533
fatty acid desaturase 6
chr13_-_2215213 3.05 ENSDART00000129773
muscular LMNA-interacting protein
chr10_-_16868211 2.98 ENSDART00000171755
stomatin (EPB72)-like 2
chr11_-_97817 2.95 ENSDART00000092903
engulfment and cell motility 2
chr14_+_32837914 2.89 ENSDART00000158888
arrestin 3b, retinal (X-arrestin)
chr20_-_30370884 2.82 ENSDART00000062429
allantoicase
chr4_-_17409533 2.82 ENSDART00000011943
phenylalanine hydroxylase
chr20_-_43771871 2.78 ENSDART00000153304
matrilin 3a
chr15_+_19682013 2.71 ENSDART00000127368
si:dkey-4p15.5
chr6_+_42338309 2.69 ENSDART00000015277
glutathione peroxidase 1b
chr10_-_19801651 2.69 ENSDART00000080430
GDNF family receptor alpha 2b
chr3_+_19299309 2.63 ENSDART00000046297
ENSDART00000146955
low density lipoprotein receptor a
chr6_+_48618512 2.56 ENSDART00000111190
si:dkey-238f9.1
chr25_+_7492663 2.53 ENSDART00000166496
catalase
chr20_+_4392687 2.50 ENSDART00000187271
im:7142702
chr10_-_42685512 2.50 ENSDART00000081347
stanniocalcin 1, like
chr11_+_45287541 2.45 ENSDART00000165321
ENSDART00000173116
pyrroline-5-carboxylate reductase 1b
chr4_+_7827261 2.39 ENSDART00000129568
phytanoyl-CoA 2-hydroxylase
chr7_-_20731078 2.37 ENSDART00000188267
chromodomain helicase DNA binding protein 3
chr24_-_17047918 2.37 ENSDART00000020204
methionine sulfoxide reductase B2
chr21_-_40174647 2.35 ENSDART00000183738
ENSDART00000076840
ENSDART00000145109
solute carrier organic anion transporter family, member 2B1
chr23_-_35756115 2.35 ENSDART00000043429
junctophilin 2
chr25_+_3327071 2.35 ENSDART00000136131
ENSDART00000133243
lactate dehydrogenase Bb
chr13_-_30662403 2.32 ENSDART00000012457
si:dkey-275b16.2
chr13_-_21688176 2.32 ENSDART00000063825
shadow of prion protein
chr16_+_24626448 2.28 ENSDART00000153591
si:dkey-56f14.7
chr10_-_24371312 2.23 ENSDART00000149362
phosphatidylinositol transfer protein, alpha b
chr5_+_9428876 2.19 ENSDART00000081791
UDP glucuronosyltransferase 2 family, polypeptide A7
chr19_-_103289 2.19 ENSDART00000143118
adhesion G protein-coupled receptor B1b
chr7_+_19482084 2.18 ENSDART00000173873
si:ch211-212k18.7
chr12_+_45676667 2.18 ENSDART00000016553
si:ch73-111m19.2
chr6_+_39836474 2.16 ENSDART00000112637
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr24_-_17023392 2.14 ENSDART00000106058
prostaglandin D2 synthase b, tandem duplicate 2
chr9_+_31795343 2.14 ENSDART00000139584
integrin, beta-like 1
chr6_-_56111829 2.12 ENSDART00000154397
glucosaminyl (N-acetyl) transferase family member 7
chr21_-_30658509 2.11 ENSDART00000139764
si:dkey-22f5.9
chr6_+_39506043 2.10 ENSDART00000086260

chr16_+_14033121 2.06 ENSDART00000135844
RUN and SH3 domain containing 1
chr1_-_45553602 2.05 ENSDART00000143664
glutamate receptor, ionotropic, N-methyl D-aspartate 2B, genome duplicate b
chr2_+_37110504 2.04 ENSDART00000132794
ENSDART00000042974
solute carrier family 1 (glutamate transporter), member 8b
chr8_+_19356072 2.03 ENSDART00000063272
macrophage expressed 1, tandem duplicate 2
chr10_-_39321367 2.01 ENSDART00000129647
somatolactin beta
chr16_+_10776688 2.01 ENSDART00000161969
ENSDART00000172657
ATPase Na+/K+ transporting subunit alpha 3b
chr5_+_6892195 2.01 ENSDART00000048201
expressed sequence CR929477
chr17_+_18117029 2.00 ENSDART00000154646
ENSDART00000179739
B cell CLL/lymphoma 11Ba
chr2_+_52232630 1.97 ENSDART00000006216
phospholipid phosphatase 2a
chr12_+_33395748 1.95 ENSDART00000129458
fatty acid synthase
chr1_-_46632948 1.93 ENSDART00000148893
ENSDART00000053232
cytidine and dCMP deaminase domain containing 1
chr8_+_3820134 1.92 ENSDART00000122454
citron rho-interacting serine/threonine kinase b
chr16_-_12319822 1.92 ENSDART00000127453
ENSDART00000184526
transient receptor potential cation channel, subfamily V, member 6
chr16_+_47428721 1.89 ENSDART00000180597
ENSDART00000032309
solute carrier family 25 (mitochondrial folate carrier), member 32b
chr12_-_4346085 1.87 ENSDART00000112433
carbonic anhydrase XV c
chr2_-_24289641 1.86 ENSDART00000128784
ENSDART00000123565
ENSDART00000141922
ENSDART00000184550
ENSDART00000191469
myosin heavy chain 7-like
chr8_+_19514294 1.84 ENSDART00000170622
si:ch73-281k2.5
chr25_-_13188678 1.84 ENSDART00000125754
si:ch211-147m6.1
chr15_-_28247583 1.83 ENSDART00000112967
Rab interacting lysosomal protein
chr15_+_26600611 1.82 ENSDART00000155352
solute carrier family 47 (multidrug and toxin extrusion), member 3
chr5_+_9434288 1.82 ENSDART00000162089
UDP glucuronosyltransferase 2 family, polypeptide A7
chr16_-_17162485 1.82 ENSDART00000123011
intermediate filament family orphan 1b
chr19_-_5103313 1.76 ENSDART00000037007
triosephosphate isomerase 1a
chr9_-_21238616 1.75 ENSDART00000191840
ENSDART00000189127
COX17 cytochrome c oxidase copper chaperone
chr4_-_4932619 1.74 ENSDART00000103293
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr24_-_28245872 1.74 ENSDART00000167861
cytochrome c oxidase subunit IV isoform 1, like
chr9_+_13682133 1.72 ENSDART00000175639
membrane protein, palmitoylated 4a (MAGUK p55 subfamily member 4)
chr15_+_19681718 1.70 ENSDART00000164803
si:dkey-4p15.5
chr5_-_37103487 1.69 ENSDART00000149211
interleukin 13 receptor, alpha 2
chr11_-_18799827 1.69 ENSDART00000185438
ENSDART00000189116
ENSDART00000180504
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b
chr7_-_16205471 1.68 ENSDART00000173584
bloodthirsty-related gene family, member 5
chr18_+_8340886 1.68 ENSDART00000081132
carnitine palmitoyltransferase 1B (muscle)
chr8_-_29713595 1.67 ENSDART00000131988
ENSDART00000077637
macrophage expressed 1, tandem duplicate 1
chr16_-_18960613 1.66 ENSDART00000183197
formin homology 2 domain containing 3b
chr9_-_21238159 1.66 ENSDART00000146764
ENSDART00000102143
COX17 cytochrome c oxidase copper chaperone
chr23_-_19953089 1.65 ENSDART00000153828
ATPase plasma membrane Ca2+ transporting 3b
chr1_-_55785722 1.65 ENSDART00000142069
ENSDART00000043933
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7
chr10_-_42131408 1.64 ENSDART00000076693
STAM binding protein a
chr19_-_5103141 1.64 ENSDART00000150952
triosephosphate isomerase 1a
chr15_-_14375452 1.61 ENSDART00000160675
ENSDART00000164028
ENSDART00000171642
D4, zinc and double PHD fingers family 1
chr1_-_22726233 1.61 ENSDART00000140920
prominin 1 b
chr11_-_7320211 1.60 ENSDART00000091664
adenomatosis polyposis coli 2
chr25_-_34512102 1.56 ENSDART00000087450
Kruppel-like factor 13
chr24_-_20808283 1.54 ENSDART00000143759
vasoactive intestinal peptide receptor 1b
chr17_-_39880725 1.53 ENSDART00000184030
zmp:0000000545
chr22_-_5518117 1.50 ENSDART00000164613

chr21_-_22737228 1.49 ENSDART00000151366
F-box protein 40, tandem duplicate 2
chr8_+_2878756 1.49 ENSDART00000168107
crumbs family member 2b
chr23_+_16633951 1.47 ENSDART00000109537
ENSDART00000193323
syntaphilin b
chr6_+_52235441 1.46 ENSDART00000056319
cytochrome c oxidase subunit VIc
chr5_+_42124706 1.43 ENSDART00000020044
ENSDART00000156372
sedoheptulokinase
chr14_-_36412473 1.42 ENSDART00000128244
ENSDART00000138376
ankyrin repeat and SOCS box containing 5a
chr9_-_48700806 1.42 ENSDART00000026210
retinol dehydrogenase 1
chr20_-_14665002 1.41 ENSDART00000152816
secernin 2
chr1_+_34243650 1.40 ENSDART00000147201
solute carrier family 5 (sodium/choline cotransporter), member 7a
chr11_-_27874116 1.40 ENSDART00000180579
eukaryotic translation initiation factor 4 gamma, 3a
chr14_-_3174570 1.39 ENSDART00000163585
colony stimulating factor 1 receptor, a
chr9_-_54001502 1.38 ENSDART00000085253
midline 1
chr19_-_42571829 1.37 ENSDART00000102606
zgc:103438
chr3_+_4346854 1.37 ENSDART00000004273
si:dkey-73p2.3
chr25_-_16742438 1.36 ENSDART00000156091
polypeptide N-acetylgalactosaminyltransferase 8a, tandem duplicate 1
chr7_+_26138240 1.36 ENSDART00000193750
ENSDART00000184942
N-acetyltransferase 16
chr13_-_3351708 1.32 ENSDART00000042875
si:ch73-193i2.2
chr2_+_7818368 1.32 ENSDART00000007068
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr15_-_46718759 1.31 ENSDART00000085926
ENSDART00000154577
zgc:162872
chr19_-_27858033 1.31 ENSDART00000103898
ENSDART00000144884
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
chr5_-_38064065 1.30 ENSDART00000137181
si:dkey-111e8.5
chr9_-_46276626 1.30 ENSDART00000165238
histone deacetylase 4
chr7_+_17096281 1.30 ENSDART00000035558
HIV-1 Tat interactive protein 2
chr3_-_30609659 1.29 ENSDART00000182516
ENSDART00000187047
ENSDART00000110597
synaptotagmin III
chr23_+_28092083 1.29 ENSDART00000053958
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1a
chr17_+_33311784 1.28 ENSDART00000156229
si:ch211-132f19.7
chr7_+_16033923 1.28 ENSDART00000161669
ENSDART00000114062
inner mitochondrial membrane peptidase subunit 1
chr11_+_27133560 1.28 ENSDART00000158411
histone deacetylase 11
chr5_-_26936861 1.27 ENSDART00000191032
HtrA serine peptidase 4
chr1_+_50085640 1.27 ENSDART00000158988
ENSDART00000165973
nephronectin
chr7_+_65261354 1.24 ENSDART00000168388
beta-carotene oxygenase 1
chr24_-_25574967 1.22 ENSDART00000189828
connector enhancer of kinase suppressor of Ras 2a
chr20_-_23219964 1.21 ENSDART00000144933
DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)
chr3_-_58455289 1.20 ENSDART00000052179
cerebellar degeneration-related protein 2a
chr21_+_15713097 1.19 ENSDART00000015841
glutathione S-transferase theta 1b
chr1_+_50085440 1.19 ENSDART00000018469
ENSDART00000134988
nephronectin
chr3_+_1749793 1.19 ENSDART00000149308
si:dkeyp-52c3.7
chr25_-_35963158 1.17 ENSDART00000153612
sorting nexin 20
chr21_-_43040780 1.17 ENSDART00000187037
janus kinase and microtubule interacting protein 2
chr17_-_36904838 1.17 ENSDART00000188030

chr22_-_5933844 1.17 ENSDART00000163370
ENSDART00000189331
si:rp71-36a1.2
chr2_+_24868010 1.16 ENSDART00000078838
RAB3A, member RAS oncogene family, a
chr10_-_25543227 1.11 ENSDART00000007778
glutamate receptor, ionotropic, kainate 1a
chr16_+_50741154 1.11 ENSDART00000101627
zgc:110372
chr5_-_41834999 1.10 ENSDART00000135772
si:dkey-65b12.6
chr2_+_38924975 1.10 ENSDART00000109219
RAS (RAD and GEM)-like GTP binding 2
chr20_+_9781932 1.09 ENSDART00000053841
DDHD domain containing 1b
chr2_+_51028269 1.08 ENSDART00000161254
eukaryotic translation elongation factor 1 delta a (guanine nucleotide exchange protein)
chr13_+_31192503 1.07 ENSDART00000147936
protein tyrosine phosphatase, non-receptor type 20
chr4_-_34776147 1.07 ENSDART00000167498
si:dkey-146m20.14
chr1_-_53476758 1.06 ENSDART00000074221
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2a
chr5_+_23622177 1.05 ENSDART00000121504
connexin 27.5
chr18_-_226800 1.04 ENSDART00000165180
threonyl-tRNA synthetase-like 2
chr5_-_69004007 1.04 ENSDART00000137443
ankyrin 1, erythrocytic a
chr13_-_1085961 1.02 ENSDART00000171872
ENSDART00000166598
pleckstrin
chr10_+_25219728 1.02 ENSDART00000193829
glutamate receptor, metabotropic 5a
chr7_+_65261576 1.00 ENSDART00000169566
beta-carotene oxygenase 1
chr7_-_56606752 1.00 ENSDART00000138714
sulfotransferase family 5A, member 1
chr24_-_25256230 0.99 ENSDART00000155780
HERV-H LTR-associating 2b, tandem duplicate 1
chr17_-_3190070 0.99 ENSDART00000115027
transmembrane protein 151Bb
chr4_-_63166758 0.99 ENSDART00000192765

chr24_-_17029374 0.99 ENSDART00000039267
prostaglandin D2 synthase b, tandem duplicate 1
chr7_-_58130703 0.97 ENSDART00000172082
ankyrin 2b, neuronal
chr19_+_32855139 0.97 ENSDART00000052082
ribosomal protein L30
chr19_-_32487469 0.97 ENSDART00000050130
guanosine monophosphate reductase
chr9_-_14055959 0.96 ENSDART00000146675
fer-1-like family member 6
chr15_+_46386261 0.96 ENSDART00000191793
immunoglobulin superfamily member 11
chr8_-_18316035 0.96 ENSDART00000134534
ring finger protein 220b
chr9_-_48701035 0.94 ENSDART00000178332
retinol dehydrogenase 1
chr21_-_7687544 0.94 ENSDART00000134519
phosphodiesterase 8B
chr1_-_37000507 0.93 ENSDART00000160637
nuclear receptor subfamily 3, group C, member 2
chr15_+_22722684 0.93 ENSDART00000156760
glutamate receptor, ionotropic, kainate 4
chr18_+_8912113 0.93 ENSDART00000147467
transmembrane protein 243, mitochondrial a
chr14_+_41518257 0.93 ENSDART00000050037
cholinergic receptor, nicotinic, beta 3b (neuronal)
chr1_-_22652424 0.93 ENSDART00000036797
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr4_-_70263609 0.92 ENSDART00000163868
si:dkey-3h2.3
chr8_-_31393429 0.92 ENSDART00000192369
NIM1 serine/threonine protein kinase
chr19_-_41371978 0.91 ENSDART00000166063
ENSDART00000170343
solute carrier family 25 (aspartate/glutamate carrier), member 13
chr18_-_21806613 0.91 ENSDART00000145721
neuritin 1-like a
chr4_-_71267777 0.91 ENSDART00000169664
si:dkeyp-51g9.4
chr4_-_63558838 0.89 ENSDART00000191708
ENSDART00000190740
ENSDART00000186476
si:dkey-16p6.1
chr3_-_584950 0.89 ENSDART00000164752
diverse immunoglobulin domain-containing protein 1.1
chr25_-_16742636 0.88 ENSDART00000192486
ENSDART00000192711
polypeptide N-acetylgalactosaminyltransferase 8a, tandem duplicate 1
chr4_+_6572364 0.87 ENSDART00000122574
protein phosphatase 1, regulatory subunit 3Aa
chr10_-_41450367 0.87 ENSDART00000122682
ENSDART00000189549
calcium binding protein 1b
chr6_-_30932078 0.87 ENSDART00000028612
phosphodiesterase 4B, cAMP-specific a
chr1_+_17527342 0.86 ENSDART00000139702
ENSDART00000140076
ENSDART00000005593
caspase 3, apoptosis-related cysteine peptidase a
chr22_-_23781083 0.86 ENSDART00000166563
ENSDART00000170458
ENSDART00000166158
ENSDART00000171246
complement factor H like 3
chr22_-_17462895 0.85 ENSDART00000160415
si:ch211-197g15.6
chr22_-_17781213 0.85 ENSDART00000137984
si:ch73-63e15.2
chr22_-_6229275 0.84 ENSDART00000146045
ENSDART00000179730
si:ch211-274k16.2
chr16_-_6391275 0.83 ENSDART00000060550
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9
chr5_+_23624684 0.82 ENSDART00000051539
connexin 27.5

Network of associatons between targets according to the STRING database.

First level regulatory network of nr6a1a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.4 GO:2000392 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
1.0 6.2 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.9 2.8 GO:0000256 allantoin catabolic process(GO:0000256)
0.9 3.4 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.6 7.2 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.6 2.4 GO:0030091 protein repair(GO:0030091)
0.5 2.2 GO:0090387 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.5 1.9 GO:0070316 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.5 1.4 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.4 2.7 GO:0010269 response to selenium ion(GO:0010269)
0.4 1.2 GO:2000434 regulation of protein neddylation(GO:2000434)
0.4 3.6 GO:0006566 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.4 1.2 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.3 1.4 GO:0071674 regulation of macrophage chemotaxis(GO:0010758) positive regulation of macrophage chemotaxis(GO:0010759) regulation of odontogenesis(GO:0042481) mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675)
0.3 2.4 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.3 1.0 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.3 3.0 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.3 5.9 GO:0046688 response to copper ion(GO:0046688)
0.3 1.3 GO:0090299 regulation of neural crest formation(GO:0090299)
0.3 1.3 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.3 1.5 GO:0061438 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.3 1.5 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.3 5.1 GO:0042574 retinal metabolic process(GO:0042574)
0.2 0.7 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 2.8 GO:1902222 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.2 0.9 GO:0071387 cellular response to cortisol stimulus(GO:0071387)
0.2 1.3 GO:0005513 detection of calcium ion(GO:0005513)
0.2 1.1 GO:0019860 uracil catabolic process(GO:0006212) beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483) uracil metabolic process(GO:0019860)
0.2 6.5 GO:0007568 aging(GO:0007568)
0.2 1.0 GO:0036371 protein localization to T-tubule(GO:0036371)
0.2 3.6 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.2 2.0 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.2 1.3 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.2 2.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.4 GO:0033212 iron assimilation(GO:0033212)
0.1 1.6 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.1 1.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.4 GO:0035376 sterol import(GO:0035376) recognition of apoptotic cell(GO:0043654) cholesterol import(GO:0070508)
0.1 0.4 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.1 0.4 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 2.5 GO:0051639 actin filament network formation(GO:0051639)
0.1 2.0 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.1 2.0 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 1.7 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 1.5 GO:0006119 oxidative phosphorylation(GO:0006119)
0.1 3.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 0.4 GO:0035994 response to muscle stretch(GO:0035994)
0.1 0.7 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 0.7 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 0.9 GO:0015813 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.1 0.4 GO:0034982 mitochondrial protein processing(GO:0034982)
0.1 1.8 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 1.0 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 2.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 1.3 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 0.4 GO:0035889 otolith tethering(GO:0035889)
0.1 0.3 GO:0070255 regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
0.1 0.6 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 9.3 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 1.0 GO:0097324 melanocyte migration(GO:0097324)
0.1 2.1 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.1 1.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 3.8 GO:0051592 response to calcium ion(GO:0051592)
0.1 0.4 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) glycosylceramide biosynthetic process(GO:0046476)
0.1 2.4 GO:0021587 cerebellum morphogenesis(GO:0021587)
0.1 1.7 GO:0022904 respiratory electron transport chain(GO:0022904)
0.1 1.4 GO:0071219 cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.1 1.6 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.9 GO:0070672 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.1 0.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 1.0 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 0.9 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 1.1 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.9 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.0 1.2 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 1.0 GO:0051923 sulfation(GO:0051923)
0.0 2.2 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.6 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.5 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0 2.5 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 1.7 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 1.3 GO:0046058 cAMP metabolic process(GO:0046058)
0.0 0.3 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.0 1.2 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 1.9 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 1.5 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 3.0 GO:0006909 phagocytosis(GO:0006909)
0.0 14.9 GO:0045944 positive regulation of transcription from RNA polymerase II promoter(GO:0045944)
0.0 0.7 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.3 GO:0034112 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 0.3 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.9 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.6 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.0 1.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.7 GO:0007548 sex differentiation(GO:0007548)
0.0 0.6 GO:0009648 photoperiodism(GO:0009648)
0.0 0.5 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 1.0 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 1.5 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 1.2 GO:0015914 phospholipid transport(GO:0015914)
0.0 1.7 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.0 0.1 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.1 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 2.2 GO:0007601 visual perception(GO:0007601)
0.0 3.2 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 14.0 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)
0.0 0.7 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.5 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.3 GO:0050727 regulation of inflammatory response(GO:0050727)
0.0 0.9 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
0.0 0.3 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.7 GO:0007254 JNK cascade(GO:0007254)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.4 GO:0032433 filopodium tip(GO:0032433)
0.5 2.3 GO:0030314 junctional membrane complex(GO:0030314)
0.3 1.0 GO:1902560 GMP reductase complex(GO:1902560)
0.3 1.3 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 0.9 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.2 1.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.2 1.6 GO:0071914 prominosome(GO:0071914)
0.2 7.4 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.2 1.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 2.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 8.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.6 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.1 1.5 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 4.5 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 2.3 GO:0071565 nBAF complex(GO:0071565)
0.1 3.0 GO:0016605 PML body(GO:0016605)
0.1 2.9 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.8 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 1.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.5 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.1 1.0 GO:0030315 T-tubule(GO:0030315)
0.1 3.8 GO:0031225 anchored component of membrane(GO:0031225)
0.1 4.6 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 0.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 2.1 GO:0008305 integrin complex(GO:0008305)
0.0 0.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 2.5 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.8 GO:0031430 M band(GO:0031430)
0.0 1.4 GO:0043204 perikaryon(GO:0043204)
0.0 4.2 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.7 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 1.0 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 1.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 2.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 3.4 GO:0043235 receptor complex(GO:0043235)
0.0 1.5 GO:0016459 myosin complex(GO:0016459)
0.0 12.9 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.2 GO:0032588 trans-Golgi network membrane(GO:0032588)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.4 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.8 5.7 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.8 3.1 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.8 3.0 GO:0005521 lamin binding(GO:0005521)
0.7 2.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.7 3.6 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.7 3.4 GO:0016531 copper chaperone activity(GO:0016531)
0.7 2.0 GO:0070186 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
0.7 2.6 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.6 1.9 GO:0008517 folic acid transporter activity(GO:0008517)
0.6 8.9 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.6 2.4 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.5 4.0 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.5 2.5 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.5 2.3 GO:0046592 polyamine oxidase activity(GO:0046592)
0.4 1.4 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.3 2.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.3 1.3 GO:0033765 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.3 1.0 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.3 1.3 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.3 1.9 GO:0004126 cytidine deaminase activity(GO:0004126)
0.3 2.8 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.3 2.8 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.3 1.4 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.3 2.5 GO:0004096 catalase activity(GO:0004096)
0.3 1.5 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.2 2.2 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.2 0.9 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 1.1 GO:0002058 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.2 2.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.2 2.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.2 4.1 GO:0098988 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.2 3.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 0.8 GO:0070573 metallodipeptidase activity(GO:0070573)
0.1 0.4 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.1 0.6 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.1 1.0 GO:0001972 retinoic acid binding(GO:0001972)
0.1 1.7 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 1.8 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.1 9.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 3.1 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.5 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.7 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 2.0 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 5.4 GO:0015485 cholesterol binding(GO:0015485)
0.1 0.5 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.1 0.9 GO:1990239 steroid hormone binding(GO:1990239)
0.1 1.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.7 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.4 GO:0071814 low-density lipoprotein particle binding(GO:0030169) lipoprotein particle binding(GO:0071813) protein-lipid complex binding(GO:0071814)
0.1 0.6 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.7 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 4.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 2.7 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 1.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 1.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 4.2 GO:0050661 NADP binding(GO:0050661)
0.1 1.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 1.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.9 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 1.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.5 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.1 1.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.8 GO:0005112 Notch binding(GO:0005112)
0.1 0.7 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.6 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1 4.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.6 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 1.7 GO:0030165 PDZ domain binding(GO:0030165)
0.1 0.9 GO:2001069 glycogen binding(GO:2001069)
0.1 1.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 1.4 GO:0000339 RNA cap binding(GO:0000339)
0.1 0.6 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 1.0 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 3.0 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 1.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.4 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.9 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 1.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.4 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 1.1 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.0 0.8 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.9 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 2.6 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 2.1 GO:0005178 integrin binding(GO:0005178)
0.0 1.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 3.8 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 7.2 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.7 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 1.9 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 6.9 GO:0008236 serine-type peptidase activity(GO:0008236) serine hydrolase activity(GO:0017171)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0004960 thromboxane receptor activity(GO:0004960)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 4.4 GO:0015293 symporter activity(GO:0015293)
0.0 0.3 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.5 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 3.3 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 1.4 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 2.2 GO:0005179 hormone activity(GO:0005179)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 3.7 GO:0042393 histone binding(GO:0042393)
0.0 1.8 GO:0019955 cytokine binding(GO:0019955)
0.0 0.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 1.0 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 4.8 GO:0051015 actin filament binding(GO:0051015)
0.0 1.0 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 1.9 GO:0005262 calcium channel activity(GO:0005262)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.4 PID S1P S1P4 PATHWAY S1P4 pathway
0.2 1.7 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 1.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 1.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 0.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 3.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 2.1 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 2.5 PID FOXO PATHWAY FoxO family signaling
0.1 3.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 1.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 2.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 2.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.5 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.4 3.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3 2.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.2 4.8 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 3.4 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 2.0 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.1 1.7 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 2.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 6.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 4.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 0.7 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 0.7 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 0.9 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 2.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.6 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.9 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.7 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 1.6 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives