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PRJEB1986: zebrafish developmental stages transcriptome

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Results for nr3c2

Z-value: 0.59

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Transcription factors associated with nr3c2

Gene Symbol Gene ID Gene Info
nr3c2
ENSDARG00000102082 nuclear receptor subfamily 3, group C, member 2
nr3c2
ENSDARG00000115513 nuclear receptor subfamily 3, group C, member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr3c2dr11_v1_chr1_-_37087966_370879660.019.8e-01Click!

Activity profile of nr3c2 motif

Sorted Z-values of nr3c2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_41096058 2.16 ENSDART00000028373
fkbp5
FK506 binding protein 5
chr6_+_41099787 1.28 ENSDART00000186884
fkbp5
FK506 binding protein 5
chr18_-_24996634 0.99 ENSDART00000170210
si:ch211-196l7.4
si:ch211-196l7.4
chr15_+_37559570 0.85 ENSDART00000085522
hspb6
heat shock protein, alpha-crystallin-related, b6
chr24_-_38097305 0.84 ENSDART00000124321
crp2
C-reactive protein 2
chr10_+_33754967 0.62 ENSDART00000153442
rxfp2a
relaxin/insulin-like family peptide receptor 2a
chr15_+_40188076 0.56 ENSDART00000063779
efhd1
EF-hand domain family, member D1
chr16_+_50089417 0.56 ENSDART00000153675
nr1d2a
nuclear receptor subfamily 1, group D, member 2a
chr15_-_24883956 0.55 ENSDART00000113199
aipl1
aryl hydrocarbon receptor interacting protein-like 1
chr7_+_48288762 0.49 ENSDART00000083569
oaz2b
ornithine decarboxylase antizyme 2b
chr7_+_58699718 0.46 ENSDART00000049264
sdr16c5b
short chain dehydrogenase/reductase family 16C, member 5b
chr10_-_24689725 0.42 ENSDART00000079566
si:ch211-287a12.9
si:ch211-287a12.9
chr10_+_26667475 0.38 ENSDART00000133281
ENSDART00000147013
si:ch73-52f15.5
si:ch73-52f15.5
chr17_+_6276559 0.35 ENSDART00000131075
dusp23b
dual specificity phosphatase 23b
chr6_+_50451337 0.33 ENSDART00000155051
mych
myelocytomatosis oncogene homolog
chr9_+_22388686 0.32 ENSDART00000182731
ENSDART00000181462
dgkg
diacylglycerol kinase, gamma
chr5_+_9382301 0.32 ENSDART00000124017
ugt2a7
UDP glucuronosyltransferase 2 family, polypeptide A7
chr11_+_5880562 0.32 ENSDART00000129663
ENSDART00000130768
ENSDART00000160909
dazap1
DAZ associated protein 1
chr20_-_38836161 0.31 ENSDART00000061358
si:dkey-221h15.4
si:dkey-221h15.4
chr5_+_9417409 0.29 ENSDART00000125421
ENSDART00000130265
ugt2b5
UDP glucuronosyltransferase 2 family, polypeptide B5
chr11_+_34522554 0.25 ENSDART00000109833
zmat3
zinc finger, matrin-type 3
chr10_-_13178853 0.24 ENSDART00000163740
ENSDART00000166327
ENSDART00000160265
ENSDART00000164299
musk
muscle, skeletal, receptor tyrosine kinase
chr2_+_29257942 0.24 ENSDART00000184362
ENSDART00000025562
cdh18a
cadherin 18, type 2a
chr23_+_44732863 0.24 ENSDART00000160044
ENSDART00000172268
atp1b2a
ATPase Na+/K+ transporting subunit beta 2a
chr14_-_28001986 0.23 ENSDART00000054115
tsc22d3
TSC22 domain family, member 3
chr11_-_34147205 0.23 ENSDART00000173216
atp13a3
ATPase 13A3
chr2_-_48396061 0.22 ENSDART00000161657
si:ch211-195j11.30
si:ch211-195j11.30
chr9_+_23895711 0.20 ENSDART00000034686
cops8
COP9 signalosome subunit 8
chr18_-_19491162 0.20 ENSDART00000090413
snapc5
small nuclear RNA activating complex, polypeptide 5
chr25_-_3470910 0.20 ENSDART00000029067
ENSDART00000186737
hbp1
HMG-box transcription factor 1
chr5_+_23256187 0.17 ENSDART00000168717
ENSDART00000142915
si:dkey-125i10.3
si:dkey-125i10.3
chr17_+_29345606 0.16 ENSDART00000086164
kctd3
potassium channel tetramerization domain containing 3
chr5_+_9360394 0.16 ENSDART00000124642
FP236810.2

chr21_+_6291027 0.16 ENSDART00000180467
ENSDART00000184952
ENSDART00000184006
fnbp1b
formin binding protein 1b
chr5_+_30518441 0.15 ENSDART00000132664
hmbsa
hydroxymethylbilane synthase a
chr21_+_6290566 0.14 ENSDART00000161647
fnbp1b
formin binding protein 1b
chr22_-_36519590 0.14 ENSDART00000129318
CABZ01045212.1

chr23_-_16734009 0.14 ENSDART00000125449
si:ch211-224l10.4
si:ch211-224l10.4
chr25_+_10416583 0.13 ENSDART00000073907
ehf
ets homologous factor
chr14_+_52571134 0.13 ENSDART00000166708
rpl26
ribosomal protein L26
chr11_+_34523132 0.12 ENSDART00000192257
zmat3
zinc finger, matrin-type 3
chr9_-_30145080 0.12 ENSDART00000133746
abi3bpa
ABI family, member 3 (NESH) binding protein a
chr20_-_39391833 0.11 ENSDART00000135149
si:dkey-217m5.8
si:dkey-217m5.8
chr16_+_46430627 0.09 ENSDART00000127681
rpz6
rapunzel 6
chr24_-_23784701 0.07 ENSDART00000090368
sgk3
serum/glucocorticoid regulated kinase family, member 3
chr18_-_20608300 0.05 ENSDART00000140632
bcl2l13
BCL2 like 13
chr16_-_11932923 0.04 ENSDART00000103975
cd4-1
CD4-1 molecule
chr6_-_27057702 0.04 ENSDART00000149363
stk25a
serine/threonine kinase 25a
chr10_+_20364009 0.04 ENSDART00000186139
ENSDART00000080395
golga7
golgin A7
chr17_-_6613458 0.04 ENSDART00000175024
si:ch211-189e2.3
si:ch211-189e2.3
chr15_+_31462664 0.03 ENSDART00000174267
ENSDART00000185665
ENSDART00000060087
or102-1
odorant receptor, family C, subfamily 102, member 1
chr3_-_37476475 0.03 ENSDART00000148107
si:ch211-278a6.1
si:ch211-278a6.1
chr10_-_24689280 0.03 ENSDART00000191476
si:ch211-287a12.9
si:ch211-287a12.9
chr22_-_16275236 0.02 ENSDART00000149051
cdc14ab
cell division cycle 14Ab
chr24_-_20641000 0.02 ENSDART00000166135
zbtb47b
zinc finger and BTB domain containing 47b
chr6_+_4255319 0.01 ENSDART00000170351
nbeal1
neurobeachin-like 1
chr22_+_19538626 0.00 ENSDART00000189174
BX936298.2

Network of associatons between targets according to the STRING database.

First level regulatory network of nr3c2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.2 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.6 GO:0045762 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.2 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.2 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.0 0.5 GO:0006595 polyamine metabolic process(GO:0006595)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.2 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.6 GO:0032922 circadian regulation of gene expression(GO:0032922)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0 0.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.8 GO:0005811 lipid particle(GO:0005811)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.5 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.3 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.2 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.0 0.8 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.4 PID REG GR PATHWAY Glucocorticoid receptor regulatory network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis