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PRJEB1986: zebrafish developmental stages transcriptome

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Results for nr2f2

Z-value: 0.89

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Transcription factors associated with nr2f2

Gene Symbol Gene ID Gene Info
ENSDARG00000040926 nuclear receptor subfamily 2, group F, member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr2f2dr11_v1_chr18_-_23874929_238749290.427.4e-02Click!

Activity profile of nr2f2 motif

Sorted Z-values of nr2f2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_45128375 2.45 ENSDART00000164805
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr17_-_25737452 2.13 ENSDART00000152021
si:ch211-214p16.3
chr24_-_29586082 1.91 ENSDART00000136763
vav 3 guanine nucleotide exchange factor a
chr17_-_14613711 1.71 ENSDART00000157345
serine dehydratase-like
chr1_+_25848231 1.65 ENSDART00000027973
fatty acid binding protein 2, intestinal
chr4_-_16451375 1.61 ENSDART00000192700
ENSDART00000128835
wu:fc23c09
chr4_-_5317006 1.53 ENSDART00000150867
si:ch211-214j24.15
chr10_-_11385155 1.50 ENSDART00000064214
placenta-specific 8, tandem duplicate 1
chr7_-_26457208 1.44 ENSDART00000173519
zgc:172079
chr12_+_22607761 1.41 ENSDART00000153112
si:dkey-219e21.2
chr9_-_46382637 1.38 ENSDART00000085738
lactase
chr7_-_5487593 1.35 ENSDART00000136594
Rho guanine nucleotide exchange factor (GEF) 11
chr24_-_14712427 1.32 ENSDART00000176316
junctophilin 1a
chr22_+_35089031 1.31 ENSDART00000076040
serum response factor a
chr7_+_73444325 1.30 ENSDART00000123016
si:ch211-142d6.2
chr22_-_31517300 1.20 ENSDART00000164799
solute carrier family 6 (neurotransmitter transporter), member 6b
chr20_-_25522911 1.14 ENSDART00000063058
cytochrome P450, family 2, subfamily N, polypeptide 13
chr17_+_450956 1.11 ENSDART00000183022
ENSDART00000171386
zgc:194887
chr12_-_31457301 1.09 ENSDART00000043887
ENSDART00000148603
acyl-CoA synthetase long chain family member 5
chr9_-_9982696 1.05 ENSDART00000192548
ENSDART00000125852
UDP glucuronosyltransferase 1 family a, b
chr2_-_8102169 1.04 ENSDART00000131955
plastin 1 (I isoform)
chr5_+_8919698 1.00 ENSDART00000046440
1-acylglycerol-3-phosphate O-acyltransferase 9, like
chr19_-_677713 0.96 ENSDART00000025146
solute carrier family 6 (neutral amino acid transporter), member 19a, tandem duplicate 1
chr22_+_15331214 0.94 ENSDART00000136566
sulfotransferase family 3, cytosolic sulfotransferase 4
chr25_-_12803723 0.93 ENSDART00000158787
carbonic anhydrase Va
chr20_+_25568694 0.92 ENSDART00000063107
ENSDART00000063128
cytochrome P450, family 2, subfamily P, polypeptide 7
chr8_+_43053519 0.91 ENSDART00000147178
prion protein a
chr5_-_36549024 0.90 ENSDART00000097671
zgc:158432
chr23_-_44786844 0.89 ENSDART00000148669
si:ch73-269m23.5
chr4_+_2655358 0.88 ENSDART00000007638
B cell receptor associated protein 29
chr9_+_30633184 0.87 ENSDART00000191310
TBC1 domain family, member 4
chr5_-_3839285 0.87 ENSDART00000122292
MLX interacting protein like
chr17_+_13031497 0.86 ENSDART00000115208
F-box protein 33
chr3_+_12744083 0.85 ENSDART00000158554
ENSDART00000169545
cytochrome P450, family 2, subfamily k, polypeptide 21
chr23_-_18030399 0.84 ENSDART00000136967
peptidase M20 domain containing 1, tandem duplicate 1
chr20_-_15090862 0.83 ENSDART00000063892
ENSDART00000122592
si:dkey-239i20.2
chr4_-_31064105 0.83 ENSDART00000157670
si:dkey-11n14.1
chr7_+_65398161 0.82 ENSDART00000166109
ENSDART00000157399
ubiquitin specific peptidase 47
chr15_-_1843831 0.81 ENSDART00000156718
ENSDART00000154175
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr3_+_12732382 0.81 ENSDART00000158403
cytochrome P450, family 2, subfamily k, polypeptide 19
chr11_-_6974022 0.81 ENSDART00000172851
si:ch211-43f4.1
chr18_+_26829086 0.79 ENSDART00000098356
solute carrier family 28 (concentrative nucleoside transporter), member 1
chr12_+_26670778 0.78 ENSDART00000144355
Rho GTPase activating protein 12b
chr3_-_46410387 0.77 ENSDART00000156822
cell death-inducing p53 target 1
chr4_-_8152746 0.77 ENSDART00000012928
ENSDART00000177482
WNK lysine deficient protein kinase 1b
chr13_-_3516473 0.77 ENSDART00000146240
parkin RBR E3 ubiquitin protein ligase
chr9_+_9502610 0.76 ENSDART00000061525
ENSDART00000125174
nuclear receptor subfamily 1, group I, member 2
chr18_-_12957451 0.75 ENSDART00000140403
SLIT-ROBO Rho GTPase activating protein 1a
chr19_+_3056450 0.75 ENSDART00000141324
ENSDART00000082353
heat shock transcription factor 1
chr3_-_16227683 0.74 ENSDART00000111707
calcium channel, voltage-dependent, beta 1 subunit
chr17_-_29194219 0.74 ENSDART00000157340
spectrin, beta, non-erythrocytic 5
chr8_+_47188154 0.74 ENSDART00000137319
si:dkeyp-100a1.6
chr18_+_36037223 0.74 ENSDART00000144410
transmembrane protein 91
chr2_-_53592532 0.73 ENSDART00000184066
chemokine (C-C motif) ligand 25a
chr12_+_49125510 0.73 ENSDART00000185804

chr25_-_21085661 0.72 ENSDART00000099355
proline rich 5a (renal)
chr20_+_43379029 0.71 ENSDART00000142486
ENSDART00000186486
unc-93 homolog A
chr3_-_18805225 0.71 ENSDART00000133471
ENSDART00000131758
methionine sulfoxide reductase B1a
chr8_+_999421 0.71 ENSDART00000149528
fatty acid binding protein 1b, tandem duplicate 1
chr6_-_49873020 0.70 ENSDART00000148511
GNAS complex locus
chr24_-_1341543 0.70 ENSDART00000169341
neuropilin 1a
chr25_-_31118923 0.70 ENSDART00000009126
ENSDART00000188286
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
chr18_+_27926839 0.69 ENSDART00000191835
homeodomain interacting protein kinase 3b
chr3_-_4455951 0.69 ENSDART00000193908
ENSDART00000074077
tripartite motif containing 35-3
chr2_+_43755274 0.68 ENSDART00000138620
Rho GTPase activating protein 12a
chr4_-_858434 0.68 ENSDART00000006961
sine oculis binding protein homolog (Drosophila) b
chr25_-_19420949 0.67 ENSDART00000181338
microtubule-associated protein 1Ab
chr17_+_12408405 0.66 ENSDART00000154827
ENSDART00000048440
ENSDART00000156429
ketohexokinase
chr11_+_30314885 0.66 ENSDART00000187418
ENSDART00000123244
UDP glucuronosyltransferase 1 family, polypeptide B2
chr23_-_45504991 0.66 ENSDART00000148761
collagen type XXIV alpha 1
chr23_-_46126444 0.65 ENSDART00000030004

chr2_-_57076687 0.63 ENSDART00000161523
solute carrier family 25, member 42
chr8_-_33154677 0.63 ENSDART00000133300
zinc finger and BTB domain containing 34
chr14_+_740032 0.63 ENSDART00000165014
klotho beta
chr12_-_20362041 0.62 ENSDART00000184145
ENSDART00000105952
aquaporin 8a, tandem duplicate 2
chr7_-_58244220 0.61 ENSDART00000180450
un-named hu7910
chr15_+_47618221 0.61 ENSDART00000168722
PAF1 homolog, Paf1/RNA polymerase II complex component
chr18_+_26829362 0.61 ENSDART00000132728
solute carrier family 28 (concentrative nucleoside transporter), member 1
chr4_-_18309917 0.60 ENSDART00000189084
plexin C1
chr21_-_9446747 0.60 ENSDART00000158790
protein tyrosine phosphatase, non-receptor type 13
chr15_-_34418525 0.60 ENSDART00000147582
alkylglycerol monooxygenase
chr15_-_30857350 0.59 ENSDART00000138988
A kinase (PRKA) anchor protein 1b
chr21_-_41617372 0.59 ENSDART00000187171

chr25_-_31898552 0.59 ENSDART00000156128
si:ch73-330k17.3
chr23_+_44633858 0.59 ENSDART00000180728
si:ch73-265d7.2
chr20_+_36682051 0.58 ENSDART00000130513
nuclear receptor coactivator 1
chr21_-_21096437 0.57 ENSDART00000186552
ankyrin 1, erythrocytic b
chr24_-_11127493 0.56 ENSDART00000144066
myosin VIIA and Rab interacting protein
chr7_-_24520866 0.56 ENSDART00000077039
fatty acid amide hydrolase 2b
chr22_-_16400484 0.56 ENSDART00000135987
laminin, alpha 3
chr24_+_39137001 0.56 ENSDART00000181086
ENSDART00000183724
ENSDART00000193466
TBC1 domain family, member 24
chr11_+_6116096 0.55 ENSDART00000159680
nuclear receptor subfamily 2, group F, member 6b
chr6_+_39499623 0.55 ENSDART00000036057
si:ch211-173n18.3
chr1_-_58868306 0.55 ENSDART00000166615
dynamin 2b
chr4_-_53354589 0.54 ENSDART00000169031
si:dkey-250k10.4
chr16_+_4078240 0.53 ENSDART00000160890
inositol polyphosphate-5-phosphatase B
chr1_-_19215336 0.53 ENSDART00000162949
ENSDART00000170680
protein tyrosine phosphatase, receptor type, D, b
chr3_+_1179601 0.52 ENSDART00000173378
TRIO and F-actin binding protein b
chr3_-_1317290 0.52 ENSDART00000047094

chr15_-_2726662 0.51 ENSDART00000108856
si:ch211-235m3.5
chr13_-_9886579 0.51 ENSDART00000101926
si:ch211-117n7.7
chr7_-_38183331 0.51 ENSDART00000149382
ATP-binding cassette, sub-family C (CFTR/MRP), member 12
chr23_-_18017946 0.50 ENSDART00000104592
peptidase M20 domain containing 1, tandem duplicate 2
chr8_-_53108207 0.50 ENSDART00000111023
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
chr3_+_30257582 0.50 ENSDART00000159497
ENSDART00000103457
ENSDART00000121883
myosin binding protein C, fast type a
chr2_-_42960353 0.50 ENSDART00000098303
otoconin 90
chr25_+_34246625 0.50 ENSDART00000082578
BCL2 interacting protein 2
chr4_+_25917915 0.50 ENSDART00000138603
vezatin, adherens junctions transmembrane protein
chr12_-_36260532 0.49 ENSDART00000022533
potassium inwardly-rectifying channel, subfamily J, member 2a
chr20_+_2281933 0.49 ENSDART00000137579
si:ch73-18b11.2
chr25_+_418932 0.48 ENSDART00000059193
protogenin homolog b (Gallus gallus)
chr4_-_19693978 0.48 ENSDART00000100974
ENSDART00000040405
staphylococcal nuclease and tudor domain containing 1
chr15_+_28268135 0.48 ENSDART00000152536
ENSDART00000188550
myosin Ic, paralog b
chr20_+_50115335 0.48 ENSDART00000031139
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4b
chr15_+_47386939 0.47 ENSDART00000128224

chr25_+_22017182 0.47 ENSDART00000156517
si:dkey-217l24.1
chr13_-_37254777 0.47 ENSDART00000139734
spectrin repeat containing, nuclear envelope 2b
chr16_-_22294265 0.47 ENSDART00000124718
aquaporin 10a
chr9_+_38075851 0.46 ENSDART00000135314
calcium channel, voltage-dependent, beta 4a subunit
chr5_+_31605322 0.46 ENSDART00000135037
si:dkey-220k22.3
chr22_-_3595439 0.46 ENSDART00000083308
protein tyrosine phosphatase, receptor type, s, a
chr24_-_26715174 0.45 ENSDART00000079726
phospholipase D1b
chr17_-_15274648 0.45 ENSDART00000141257
c-ros oncogene 1 , receptor tyrosine kinase
chr5_+_43470544 0.45 ENSDART00000111587
Rho-related BTB domain containing 2a
chr3_+_12718100 0.44 ENSDART00000162343
ENSDART00000192425
cytochrome P450, family 2, subfamily k, polypeptide 20
chr5_-_67115872 0.44 ENSDART00000065262
ribosomal protein S6 kinase, polypeptide 4
chr8_+_36339470 0.44 ENSDART00000191250

chr9_+_32859967 0.43 ENSDART00000168992
si:dkey-145p14.5
chr1_+_58094551 0.42 ENSDART00000146316
si:ch211-114l13.1
chr5_-_24124118 0.42 ENSDART00000051550
capping protein (actin filament), gelsolin-like a
chr5_-_33607062 0.42 ENSDART00000048350
si:dkey-34e4.1
chr20_-_52967878 0.42 ENSDART00000164460
GATA binding protein 4
chr13_-_41546779 0.42 ENSDART00000163331
protocadherin-related 15a
chr18_+_5172848 0.41 ENSDART00000190642

chr2_+_3533458 0.41 ENSDART00000133007
glutamic pyruvate transaminase (alanine aminotransferase) 2, like
chr25_-_18002937 0.40 ENSDART00000149696
centrosomal protein 290
chr17_+_25856671 0.39 ENSDART00000064817
WAPL cohesin release factor a
chr25_-_35143360 0.39 ENSDART00000188033
zgc:165555
chr20_+_39250673 0.39 ENSDART00000153003
RALBP1 associated Eps domain containing 1
chr19_-_27564980 0.39 ENSDART00000171967
si:dkeyp-46h3.8
chr21_+_34992550 0.38 ENSDART00000109041
ENSDART00000135400
transmembrane protease, serine 15
chr25_+_34247353 0.38 ENSDART00000148914
BCL2 interacting protein 2
chr20_+_46213553 0.38 ENSDART00000100532
syntaxin 7-like
chr3_+_12755535 0.38 ENSDART00000161286
cytochrome P450, family 2, subfamily K, polypeptide17
chr4_-_9533345 0.38 ENSDART00000128501
si:ch73-139j3.4
chr6_-_55354004 0.38 ENSDART00000165911
PDX1 C-terminal inhibiting factor 1
chr18_-_37007294 0.38 ENSDART00000088309
mitogen-activated protein kinase kinase kinase 10
chr22_+_15323930 0.38 ENSDART00000142416
si:dkey-236e20.3
chr7_+_38267136 0.38 ENSDART00000173613
G patch domain containing 1
chr7_+_59649399 0.37 ENSDART00000123520
ENSDART00000040771
ribosomal protein L34
chr11_+_33284837 0.37 ENSDART00000166239
ENSDART00000111412
NTPase, KAP family P-loop domain containing 1
chr5_+_32009080 0.37 ENSDART00000186885
suppressor of cancer cell invasion
chr4_-_47096170 0.37 ENSDART00000161079
si:dkey-26m3.3
chr21_-_28523548 0.37 ENSDART00000077910
ependymin-like 2
chr4_+_33547662 0.37 ENSDART00000150439
si:dkey-84h14.2
chr19_-_3056235 0.36 ENSDART00000137020
block of proliferation 1
chr4_-_9579299 0.36 ENSDART00000183079
ENSDART00000192968
ENSDART00000091809
SH3 and multiple ankyrin repeat domains 3b
chr10_-_21953643 0.36 ENSDART00000188921
ENSDART00000193569

chr17_-_6076266 0.35 ENSDART00000171084
epoxide hydrolase 2, cytoplasmic
chr8_-_19051906 0.35 ENSDART00000089024
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Bb
chr2_+_42715995 0.35 ENSDART00000143419
ENSDART00000183914
ENSDART00000184371
ENSDART00000185485
ENSDART00000037332
finTRIM family, member 12
chr5_-_7897316 0.35 ENSDART00000160743
ENSDART00000160912
opsin 4xb
chr1_-_44314 0.34 ENSDART00000160050
transmembrane protein 39A
chr9_+_17984358 0.34 ENSDART00000192399
A kinase (PRKA) anchor protein 11
chr2_-_20120904 0.34 ENSDART00000186002
ENSDART00000124724
dihydropyrimidine dehydrogenase b
chr7_-_51953807 0.34 ENSDART00000174102
ENSDART00000145645
ENSDART00000052054
cytochrome P450, family 2, subfamily X, polypeptide 10.2
chr2_+_3533117 0.34 ENSDART00000132572
glutamic pyruvate transaminase (alanine aminotransferase) 2, like
chr9_-_33121535 0.34 ENSDART00000166371
ENSDART00000138052
zgc:172014
chr4_-_63558838 0.34 ENSDART00000191708
ENSDART00000190740
ENSDART00000186476
si:dkey-16p6.1
chr3_+_12710350 0.34 ENSDART00000157959
cytochrome P450, family 2, subfamily K, polypeptide 18
chr4_+_34119824 0.33 ENSDART00000165637
si:ch211-223g7.6
chr18_-_37007061 0.33 ENSDART00000136432
mitogen-activated protein kinase kinase kinase 10
chr6_-_1587291 0.33 ENSDART00000067592
ENSDART00000178877
zgc:123305
chr18_-_158541 0.33 ENSDART00000188914
ENSDART00000191052
transient receptor potential cation channel, subfamily M, member 7
chr12_-_14551077 0.33 ENSDART00000188717

chr9_+_24936496 0.33 ENSDART00000157474
solute carrier family 39 (zinc transporter), member 10
chr4_-_36139585 0.33 ENSDART00000132071
zinc finger protein 992
chr23_-_46040618 0.32 ENSDART00000161415

chr21_+_1119046 0.31 ENSDART00000184678

chr22_-_20814450 0.31 ENSDART00000089076
DOT1-like histone H3K79 methyltransferase
chr11_+_6115621 0.30 ENSDART00000165031
ENSDART00000027666
ENSDART00000161458
nuclear receptor subfamily 2, group F, member 6b
chr18_+_45200043 0.30 ENSDART00000015786
LARGE xylosyl- and glucuronyltransferase 2
chr18_-_39200557 0.30 ENSDART00000132367
ENSDART00000183672
si:ch211-235f12.2
mitogen-activated protein kinase 6
chr1_-_52292235 0.30 ENSDART00000132638
si:dkey-121b10.7
chr21_+_7188943 0.30 ENSDART00000172174
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr17_-_6076084 0.30 ENSDART00000058890
epoxide hydrolase 2, cytoplasmic
chr12_-_6033824 0.30 ENSDART00000131301
ENSDART00000139419
ENSDART00000032050
glucose-6-phosphatase a, catalytic subunit, tandem duplicate 1
chr5_-_62317496 0.30 ENSDART00000180089
zgc:85789
chr13_-_33114933 0.29 ENSDART00000140543
ENSDART00000075953
zinc finger, FYVE domain containing 26
chr12_+_30368145 0.29 ENSDART00000153454
si:ch211-225b10.4
chr7_-_52096498 0.29 ENSDART00000098688
ENSDART00000098690
cytochrome P450, family 2, subfamily X, polypeptide 10.2
chr9_-_22822084 0.29 ENSDART00000142020
nebulin
chr23_-_24493768 0.29 ENSDART00000135559
ENSDART00000046933
sulfotransferase family 1, cytosolic sulfotransferase 5
chr4_+_53246788 0.29 ENSDART00000184708
ENSDART00000169256
si:dkey-250k10.1
chr5_-_24238733 0.29 ENSDART00000138170
phospholipid scramblase 3a
chr25_+_34247107 0.28 ENSDART00000148507
BCL2 interacting protein 2
chr9_+_54984537 0.28 ENSDART00000029528
motile sperm domain containing 2
chr16_+_11558868 0.28 ENSDART00000112497
ENSDART00000180445
zgc:198329
chr21_+_40944530 0.28 ENSDART00000022976
potassium channel tetramerization domain containing 16b
chr4_+_69619 0.28 ENSDART00000164425
MANSC domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of nr2f2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0006549 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
0.4 1.1 GO:2000193 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.3 1.3 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.3 0.9 GO:0009750 response to fructose(GO:0009750)
0.2 0.7 GO:0072679 thymocyte migration(GO:0072679)
0.2 0.9 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.7 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.7 GO:0002164 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.1 0.5 GO:0071871 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.1 0.4 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.1 0.5 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.1 0.6 GO:0042264 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.6 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.3 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 0.3 GO:0046125 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.5 GO:0032530 regulation of microvillus organization(GO:0032530) regulation of microvillus assembly(GO:0032534)
0.1 1.0 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.3 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.7 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.1 1.2 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.1 0.5 GO:0052651 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.3 GO:0005991 trehalose metabolic process(GO:0005991)
0.1 0.3 GO:0046689 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.1 1.4 GO:1901642 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.1 4.7 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.1 0.3 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.1 0.3 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1 0.3 GO:0034729 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.1 0.8 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.1 0.4 GO:0016572 histone phosphorylation(GO:0016572)
0.1 0.2 GO:0019483 beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
0.1 0.4 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.1 0.4 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 2.6 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.1 0.7 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.5 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.4 GO:0016559 peroxisome fission(GO:0016559)
0.1 0.4 GO:0097107 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 0.2 GO:0072020 proximal straight tubule development(GO:0072020)
0.0 0.8 GO:1903286 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 1.0 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 1.2 GO:0051923 sulfation(GO:0051923)
0.0 1.3 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.3 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.0 0.1 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 1.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.5 GO:0050482 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.1 GO:0071548 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401) short-chain fatty acid catabolic process(GO:0019626) response to dexamethasone(GO:0071548)
0.0 0.5 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.0 1.2 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.7 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.8 GO:0009408 response to heat(GO:0009408)
0.0 0.6 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.5 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.6 GO:1902287 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.8 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.7 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 0.4 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.2 GO:0016576 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.2 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.2 GO:1901998 toxin transport(GO:1901998)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:0061178 insulin secretion involved in cellular response to glucose stimulus(GO:0035773) regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.6 GO:0060841 venous blood vessel development(GO:0060841)
0.0 0.2 GO:0016139 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.0 0.3 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.1 GO:0009078 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.0 0.1 GO:0098920 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.0 0.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.3 GO:0046473 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 0.1 GO:1905048 regulation of metallopeptidase activity(GO:1905048)
0.0 0.8 GO:0031647 regulation of protein stability(GO:0031647)
0.0 1.2 GO:0051693 actin filament capping(GO:0051693)
0.0 0.2 GO:0042493 response to drug(GO:0042493)
0.0 0.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.2 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.1 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.1 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.3 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.1 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.9 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.6 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.1 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.8 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.7 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:0051932 synaptic transmission, GABAergic(GO:0051932)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0030314 junctional membrane complex(GO:0030314)
0.2 0.7 GO:0005592 collagen type XI trimer(GO:0005592)
0.2 0.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.4 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.5 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.7 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.5 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 1.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.7 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.6 GO:0005902 microvillus(GO:0005902)
0.0 0.7 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0016841 ammonia-lyase activity(GO:0016841)
0.2 0.6 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.2 0.6 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.2 0.7 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.2 2.0 GO:0008422 beta-glucosidase activity(GO:0008422)
0.2 2.4 GO:0005504 fatty acid binding(GO:0005504)
0.2 0.6 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.7 GO:0051430 mu-type opioid receptor binding(GO:0031852) dopamine receptor binding(GO:0050780) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 1.0 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.5 GO:0015105 arsenite transmembrane transporter activity(GO:0015105)
0.1 0.9 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 1.2 GO:0004046 aminoacylase activity(GO:0004046)
0.1 1.2 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.1 1.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 1.1 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.3 GO:0015927 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
0.1 0.4 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.8 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 5.5 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 0.3 GO:0019777 Atg12 transferase activity(GO:0019777)
0.1 0.7 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.3 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.1 0.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.3 GO:0002058 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.1 0.6 GO:0015250 water channel activity(GO:0015250)
0.1 0.6 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.5 GO:0004630 phospholipase D activity(GO:0004630)
0.1 0.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.7 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.5 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.2 GO:0004557 alpha-galactosidase activity(GO:0004557)
0.1 0.4 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 1.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.5 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.8 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.6 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 2.6 GO:0015370 solute:sodium symporter activity(GO:0015370)
0.0 0.6 GO:0030507 spectrin binding(GO:0030507)
0.0 2.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 2.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.3 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.9 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.5 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.3 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.1 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.2 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 1.1 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.1 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.6 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.3 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.5 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.7 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.4 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.5 PID FGF PATHWAY FGF signaling pathway
0.0 0.5 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.8 PID P73PATHWAY p73 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 1.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 0.7 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 1.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.6 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade