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PRJEB1986: zebrafish developmental stages transcriptome

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Results for nr2c2

Z-value: 0.95

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Transcription factors associated with nr2c2

Gene Symbol Gene ID Gene Info
ENSDARG00000042477 nuclear receptor subfamily 2, group C, member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr2c2dr11_v1_chr8_+_53120278_53120278-0.606.3e-03Click!

Activity profile of nr2c2 motif

Sorted Z-values of nr2c2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_45705525 5.99 ENSDART00000148959
endothelin receptor type Ab
chr4_-_16451375 5.65 ENSDART00000192700
ENSDART00000128835
wu:fc23c09
chr21_-_44512893 4.27 ENSDART00000166853
zgc:136410
chr16_-_5115993 3.58 ENSDART00000138654
ttk protein kinase
chr24_-_1021318 3.26 ENSDART00000181403
v-ral simian leukemia viral oncogene homolog Aa (ras related)
chr22_-_7050 3.11 ENSDART00000127829
ATPase family, AAA domain containing 3
chr4_+_12031958 2.99 ENSDART00000044154
troponin T2c, cardiac
chr14_+_989733 2.99 ENSDART00000161487
ENSDART00000127317
si:ch73-308l14.2
chr19_-_8534985 2.94 ENSDART00000191064
dolichyl-phosphate mannosyltransferase polypeptide 3
chr8_+_15251448 2.66 ENSDART00000063717
zgc:171480
chr19_-_3056235 2.66 ENSDART00000137020
block of proliferation 1
chr3_-_31804481 2.43 ENSDART00000028270
glial fibrillary acidic protein
chr13_-_37127970 2.42 ENSDART00000135510
spectrin repeat containing, nuclear envelope 2b
chr22_-_17595310 2.37 ENSDART00000099056
glutathione peroxidase 4a
chr23_-_10696626 2.30 ENSDART00000177571
forkhead box P1a
chr1_-_44933094 2.27 ENSDART00000147527
si:dkey-9i23.14
chr5_+_43870389 2.10 ENSDART00000141002
zgc:112966
chr22_-_15587360 2.02 ENSDART00000142717
ENSDART00000138978
tropomyosin 4a
chr1_+_15062 2.01 ENSDART00000169005
centrosomal protein 97
chr3_-_25119839 1.99 ENSDART00000154724
chondroadherin-like a
chr25_+_27410352 1.98 ENSDART00000154362
protection of telomeres 1 homolog
chr18_+_1615 1.95 ENSDART00000082450
homer scaffolding protein 2
chr23_+_44634187 1.93 ENSDART00000143688
si:ch73-265d7.2
chr21_-_308852 1.89 ENSDART00000151613
LHFPL tetraspan subfamily member 2a
chr6_-_11523987 1.85 ENSDART00000189363
GULP, engulfment adaptor PTB domain containing 1b
chr14_+_97017 1.79 ENSDART00000159300
ENSDART00000169523
minichromosome maintenance complex component 7
chr23_+_2914577 1.78 ENSDART00000184897
zgc:158828
chr2_-_42960353 1.78 ENSDART00000098303
otoconin 90
chr9_-_33121535 1.77 ENSDART00000166371
ENSDART00000138052
zgc:172014
chr9_-_32300783 1.76 ENSDART00000078596
heat shock 60 protein 1
chr20_+_36806398 1.74 ENSDART00000153317
ABRA C-terminal like
chr19_-_27564458 1.73 ENSDART00000123155
si:dkeyp-46h3.6
chr7_+_25000060 1.72 ENSDART00000039265
ENSDART00000141814
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr9_-_32300611 1.69 ENSDART00000127938
heat shock 60 protein 1
chr16_+_54875530 1.68 ENSDART00000149795
nuclear receptor subfamily 0, group B, member 2a
chr21_-_22317920 1.67 ENSDART00000191083
ENSDART00000108701
glycerophosphodiester phosphodiesterase domain containing 4b
chr3_+_39566999 1.64 ENSDART00000146867
aldolase a, fructose-bisphosphate, a
chr18_+_30441740 1.64 ENSDART00000189074
Gse1 coiled-coil protein
chr2_+_6067371 1.63 ENSDART00000053868
ENSDART00000145244
aldehyde dehydrogenase 9 family, member A1b
chr3_+_301479 1.62 ENSDART00000165169

chr9_+_22782027 1.58 ENSDART00000090816
replication timing regulatory factor 1
chr25_+_418932 1.57 ENSDART00000059193
protogenin homolog b (Gallus gallus)
chr23_-_16737161 1.55 ENSDART00000132573
si:ch211-224l10.4
chr9_+_33216945 1.53 ENSDART00000134029
si:ch211-125e6.12
chr25_+_18587338 1.50 ENSDART00000180287
MET proto-oncogene, receptor tyrosine kinase
chr3_-_34561624 1.46 ENSDART00000129313
septin 9a
chr3_+_34121156 1.44 ENSDART00000174929
aldehyde dehydrogenase 3 family, member B1
chr20_+_26943072 1.43 ENSDART00000153215
cell division cycle associated 4
chr8_+_39802506 1.43 ENSDART00000018862
HNF1 homeobox a
chr23_+_30730121 1.40 ENSDART00000134141
additional sex combs like transcriptional regulator 1
chr14_+_22498757 1.39 ENSDART00000021657
SMYD family member 5
chr3_-_36419641 1.37 ENSDART00000173545
component of oligomeric golgi complex 1
chr1_-_59232267 1.37 ENSDART00000169658
ENSDART00000163257
A kinase (PRKA) anchor protein 8-like
chr8_+_36570508 1.35 ENSDART00000145868
polymerase (DNA directed), delta 2, regulatory subunit
chr18_-_43866526 1.35 ENSDART00000111309
trehalase (brush-border membrane glycoprotein)
chr7_+_22718251 1.32 ENSDART00000027718
ENSDART00000143341
fragile X mental retardation, autosomal homolog 2
chr20_-_25877793 1.32 ENSDART00000177333
ENSDART00000184619
exocyst complex component 1
chr20_-_45807982 1.32 ENSDART00000074546
fermitin family member 1
chr1_-_51720633 1.31 ENSDART00000045894
ribonuclease H2, subunit A
chr7_+_19374683 1.29 ENSDART00000162700
small nuclear ribonucleoprotein polypeptide F
chr4_+_47656992 1.29 ENSDART00000161148
zinc finger protein 1040
chr6_+_40775800 1.27 ENSDART00000085090
si:ch211-157b11.8
chr11_+_6116503 1.27 ENSDART00000176170
nuclear receptor subfamily 2, group F, member 6b
chr19_+_20274944 1.27 ENSDART00000151237
oxidoreductase NAD-binding domain containing 1
chr4_-_25858620 1.27 ENSDART00000128968
nuclear receptor subfamily 2, group C, member 1
chr5_+_35786141 1.27 ENSDART00000022043
ENSDART00000127383
StAR-related lipid transfer (START) domain containing 8
chr13_-_39159810 1.27 ENSDART00000131508
collagen, type IX, alpha 1b
chr15_-_35246742 1.26 ENSDART00000131479
mitochondrial fission factor
chr18_-_127558 1.26 ENSDART00000149556
transient receptor potential cation channel, subfamily M, member 7
chr12_+_19138452 1.23 ENSDART00000141346
ENSDART00000066397
PHD finger protein 5A
chr9_-_32684008 1.23 ENSDART00000041751
excision repair cross-complementation group 1
chr12_+_48681601 1.22 ENSDART00000187831
uroporphyrinogen III synthase
chr18_-_48508585 1.20 ENSDART00000133364
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 4
chr12_+_27024676 1.19 ENSDART00000153104
male-specific lethal 1 homolog b (Drosophila)
chr17_+_53424415 1.19 ENSDART00000157022
solute carrier family 9 member A1b
chr8_+_23802384 1.18 ENSDART00000137820
si:ch211-163l21.8
chr10_+_31244619 1.18 ENSDART00000145562
ENSDART00000184412
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr6_+_1787160 1.17 ENSDART00000113505
myosin, light chain 9b, regulatory
chr9_+_32860345 1.16 ENSDART00000121751
si:dkey-145p14.5
chr6_+_52931841 1.14 ENSDART00000174358
si:dkeyp-3f10.12
chr2_-_56649883 1.13 ENSDART00000191786
glutathione peroxidase 4b
chr18_-_19819812 1.13 ENSDART00000060344
alpha and gamma adaptin binding protein
chr9_+_32978302 1.13 ENSDART00000007630
nescient helix loop helix 2
chr3_+_25999477 1.12 ENSDART00000024316
minichromosome maintenance complex component 5
chr10_+_43994471 1.11 ENSDART00000138242
ENSDART00000186359
claudin 5b
chr5_-_3839285 1.10 ENSDART00000122292
MLX interacting protein like
chr21_+_8198652 1.09 ENSDART00000011096
nuclear receptor subfamily 6, group A, member 1b
chr17_-_25303486 1.08 ENSDART00000162235
peptidylprolyl isomerase E (cyclophilin E)
chr16_-_39131666 1.08 ENSDART00000075517
growth differentiation factor 6a
chr23_+_30736895 1.08 ENSDART00000042944
additional sex combs like transcriptional regulator 1
chr2_-_25143373 1.07 ENSDART00000160108
neutral cholesterol ester hydrolase 1a
chr13_-_39160018 1.06 ENSDART00000168795
collagen, type IX, alpha 1b
chr2_-_7666021 1.06 ENSDART00000180007

chr20_-_34164278 1.04 ENSDART00000153128
hemicentin 1
chr5_-_32890807 1.04 ENSDART00000007512
polymerase (DNA directed), epsilon 3 (p17 subunit)
chr17_-_22137199 1.04 ENSDART00000089689
mitochondrial ribosomal protein S5
chr15_+_8394819 1.03 ENSDART00000147086
transmembrane protein 160
chr21_-_1640547 1.01 ENSDART00000151041
zgc:152948
chr18_-_34549721 1.01 ENSDART00000137101
ENSDART00000021880
signal sequence receptor, gamma
chr18_-_48517040 1.00 ENSDART00000143645
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 3
chr18_-_18850302 1.00 ENSDART00000131965
ENSDART00000167624
transglutaminase 2, like
chr3_+_40289418 0.98 ENSDART00000017304
cleavage and polyadenylation specific factor 4
chr24_+_81527 0.98 ENSDART00000192139
reversion-inducing-cysteine-rich protein with kazal motifs
chr3_-_18792492 0.98 ENSDART00000134208
ENSDART00000034373
hydroxyacylglutathione hydrolase
chr6_-_14004772 0.98 ENSDART00000185629
zgc:92027
chr5_-_26330313 0.97 ENSDART00000148656
ARVCF, delta catenin family member b
chr22_-_14262115 0.97 ENSDART00000168264
si:ch211-246m6.5
chr13_-_36566260 0.96 ENSDART00000030133
synaptojanin 2 binding protein
chr4_-_56157199 0.96 ENSDART00000169806
si:ch211-207e19.15
chr4_+_38981587 0.96 ENSDART00000142713
si:dkey-66k12.3
chr8_+_36570791 0.95 ENSDART00000145566
ENSDART00000180527
polymerase (DNA directed), delta 2, regulatory subunit
chr1_+_12195700 0.95 ENSDART00000040307
tudor domain containing 7 a
chr13_-_25199260 0.94 ENSDART00000057605
adenosine kinase a
chr3_+_31680592 0.94 ENSDART00000172456
myosin, light chain kinase 5
chr8_+_32742650 0.94 ENSDART00000138117
hemicentin 2
chr24_-_21172122 0.93 ENSDART00000154259
ATPase H+ transporting V1 subunit Ab
chr13_+_713941 0.93 ENSDART00000109737
cytochrome c oxidase assembly homolog 15 (yeast)
chr9_-_25255490 0.93 ENSDART00000141502
5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a
chr1_+_24387659 0.92 ENSDART00000130356
quinoid dihydropteridine reductase b2
chr25_-_25575717 0.92 ENSDART00000067138
hypermethylated in cancer 1 like
chr7_+_35193832 0.92 ENSDART00000189002
zinc finger, DHHC-type containing 1
chr9_+_32859967 0.90 ENSDART00000168992
si:dkey-145p14.5
chr9_+_32301456 0.90 ENSDART00000078608
ENSDART00000185153
ENSDART00000144947
heat shock 10 protein 1
chr14_-_48103207 0.89 ENSDART00000056712
electron-transferring-flavoprotein dehydrogenase
chr17_+_32374876 0.89 ENSDART00000183851
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b
chr4_-_16833518 0.89 ENSDART00000179867
lactate dehydrogenase Ba
chr8_+_23439340 0.89 ENSDART00000109932
ENSDART00000185469
forkhead box P3b
chr23_-_24234371 0.88 ENSDART00000124539
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
chr5_+_37035978 0.88 ENSDART00000167418
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr17_-_49407091 0.87 ENSDART00000021950
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b
chr7_+_38267136 0.86 ENSDART00000173613
G patch domain containing 1
chr20_+_25445826 0.86 ENSDART00000012581
phosphoribosylformylglycinamidine synthase
chr9_-_28990649 0.86 ENSDART00000078823
protein tyrosine phosphatase, non-receptor type 4a
chr16_+_23972126 0.86 ENSDART00000132742
ENSDART00000145330
apolipoprotein C-I
chr19_+_2877079 0.85 ENSDART00000160847
HGH1 homolog (S. cerevisiae)
chr1_+_58353661 0.85 ENSDART00000140074
si:dkey-222h21.2
chr1_-_26664840 0.85 ENSDART00000102500
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr16_-_29146624 0.85 ENSDART00000159814
ENSDART00000009826
myocyte enhancer factor 2d
chr14_-_6286966 0.85 ENSDART00000168174
elongator complex protein 1
chr13_-_35808904 0.84 ENSDART00000171667
mitogen-activated protein kinase kinase kinase 4
chr17_-_45733401 0.84 ENSDART00000185727
ADP-ribosylation factor 6b
chr2_-_22659450 0.83 ENSDART00000115025
THAP domain containing 4
chr7_+_23940933 0.83 ENSDART00000173628
si:dkey-183c6.7
chr20_-_21994901 0.82 ENSDART00000004984
dishevelled associated activator of morphogenesis 1b
chr23_-_29394505 0.81 ENSDART00000017728
phosphogluconate dehydrogenase
chr25_+_25766033 0.81 ENSDART00000103638
ENSDART00000039952
isocitrate dehydrogenase 3 (NAD+) alpha
chr25_-_16076257 0.81 ENSDART00000140780
ovochymase 2
chr18_-_7448047 0.80 ENSDART00000193213
ENSDART00000131940
ENSDART00000186944
ENSDART00000052803
si:dkey-30c15.10
chr21_-_21515466 0.80 ENSDART00000147593
nectin cell adhesion molecule 3b
chr13_-_24260609 0.80 ENSDART00000138747
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr17_+_24036791 0.80 ENSDART00000140767
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2b
chr20_+_46286082 0.79 ENSDART00000073519
trace amine associated receptor 14f
chr1_-_44581937 0.79 ENSDART00000009858
thioredoxin-related transmembrane protein 2b
chr14_+_30413758 0.78 ENSDART00000092953
CCR4-NOT transcription complex, subunit 7
chr18_-_29972709 0.78 ENSDART00000131207
si:ch211-220f16.2
chr9_-_1939232 0.78 ENSDART00000146131
homeobox D3a
chr10_+_20128267 0.78 ENSDART00000064615
dematin actin binding protein
chr10_-_21362071 0.76 ENSDART00000125167
avidin
chr11_-_6974022 0.76 ENSDART00000172851
si:ch211-43f4.1
chr4_+_37503994 0.76 ENSDART00000158217
zinc finger protein 1102
chr23_-_28808480 0.76 ENSDART00000078167
DNA fragmentation factor, alpha polypeptide
chr13_+_7241170 0.75 ENSDART00000109434
apoptosis-inducing factor, mitochondrion-associated, 2
chr25_+_15647993 0.75 ENSDART00000186578
ENSDART00000031828
spondin 1b
chr5_-_41860556 0.74 ENSDART00000140154
si:dkey-65b12.12
chr7_+_17543487 0.73 ENSDART00000126652
Danio rerio novel immune-type receptor 1l (nitr1l), mRNA.
chr3_-_7134113 0.73 ENSDART00000180849

chr7_+_5936601 0.72 ENSDART00000181693
si:dkey-23a13.11
chr2_+_58377395 0.72 ENSDART00000193511
VAMP (vesicle-associated membrane protein)-associated protein A, like
chr19_+_32158010 0.71 ENSDART00000005255
mitochondrial ribosomal protein L53
chr18_+_14529005 0.71 ENSDART00000186379
potassium voltage-gated channel, subfamily G, member 4a
chr3_+_50201240 0.71 ENSDART00000156347
epsin 3a
chr2_+_35880600 0.71 ENSDART00000004277
laminin, gamma 1
chr12_-_33568174 0.71 ENSDART00000142329
tudor and KH domain containing
chr12_+_26670778 0.71 ENSDART00000144355
Rho GTPase activating protein 12b
chr20_-_49117438 0.71 ENSDART00000057700
N(alpha)-acetyltransferase 20, NatB catalytic subunit
chr11_+_11751006 0.71 ENSDART00000180372
ENSDART00000081018
junction plakoglobin a
chr24_+_36389536 0.70 ENSDART00000179898
mitogen-activated protein kinase kinase kinase 14b
chr3_-_32590164 0.70 ENSDART00000151151
tetraspanin 4b
chr17_-_40110782 0.69 ENSDART00000126929
si:dkey-187k19.2
chr3_+_27770110 0.69 ENSDART00000017962
enoyl-CoA delta isomerase 1
chr10_+_24692076 0.69 ENSDART00000181600
transmembrane phosphatase with tensin homology
chr8_+_2530065 0.69 ENSDART00000063943
mitochondrial ribosomal protein L40
chr19_-_874888 0.69 ENSDART00000007206
eomesodermin homolog a
chr16_-_24605969 0.68 ENSDART00000163305
ENSDART00000167121
FXYD domain containing ion transport regulator 6 like
chr10_+_17235370 0.68 ENSDART00000038780
signal peptide peptidase 3
chr16_-_32128345 0.68 ENSDART00000102100
ENSDART00000137699
CCR4-NOT transcription complex, subunit 3a
chr1_+_54737353 0.67 ENSDART00000130675
ENSDART00000162075
phosphatidylinositol 4-kinase type 2 alpha
chr14_+_34501245 0.67 ENSDART00000131424
lymphocyte cytosolic protein 2b
chr16_+_42829735 0.67 ENSDART00000014956
polymerase (RNA) III (DNA directed) polypeptide G like b
chr19_-_24484758 0.67 ENSDART00000052422
metaxin 1b
chr10_+_589501 0.65 ENSDART00000188415

chr9_+_24936496 0.65 ENSDART00000157474
solute carrier family 39 (zinc transporter), member 10
chr2_-_22660232 0.65 ENSDART00000174742
THAP domain containing 4
chr23_+_8797143 0.65 ENSDART00000132992
SRY (sex determining region Y)-box 18
chr9_-_43082945 0.64 ENSDART00000142257
coiled-coil domain containing 141
chr6_-_21873266 0.64 ENSDART00000151658
ENSDART00000151152
ENSDART00000151179
si:dkey-19e4.5
chr19_+_2631565 0.64 ENSDART00000171487
family with sequence similarity 126, member A
chr10_+_35417099 0.64 ENSDART00000063398
HERV-H LTR-associating 2a, tandem duplicate 1
chr2_-_55853943 0.64 ENSDART00000122576
retinal homeobox gene 2
chr4_-_42074960 0.64 ENSDART00000164406
zgc:174696

Network of associatons between targets according to the STRING database.

First level regulatory network of nr2c2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:1905133 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.9 3.4 GO:0045041 positive regulation of interleukin-6 production(GO:0032755) protein import into mitochondrial intermembrane space(GO:0045041)
0.9 6.0 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.6 1.8 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.6 1.2 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.5 1.4 GO:0005991 trehalose metabolic process(GO:0005991)
0.4 1.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.4 2.0 GO:0051972 regulation of telomerase activity(GO:0051972)
0.3 2.1 GO:0001955 blood vessel maturation(GO:0001955)
0.3 1.0 GO:0006089 lactate metabolic process(GO:0006089)
0.3 6.5 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.3 0.9 GO:0050995 negative regulation of lipid transport(GO:0032369) negative regulation of lipid catabolic process(GO:0050995)
0.3 0.8 GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis.(GO:0002926)
0.3 0.8 GO:0071918 urea transmembrane transport(GO:0071918)
0.2 1.9 GO:0021627 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.2 1.9 GO:0046546 development of primary male sexual characteristics(GO:0046546)
0.2 0.7 GO:0055109 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.2 1.1 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2 0.7 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.2 2.9 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.2 0.6 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.2 1.2 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.2 0.5 GO:0033335 anal fin development(GO:0033335)
0.2 0.5 GO:0019408 dolichol biosynthetic process(GO:0019408)
0.2 0.9 GO:0044209 AMP salvage(GO:0044209)
0.1 1.6 GO:0021707 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 2.7 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.4 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.1 0.6 GO:0051645 Golgi localization(GO:0051645)
0.1 0.7 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.4 GO:0007414 axonal defasciculation(GO:0007414)
0.1 0.9 GO:0090497 skin morphogenesis(GO:0043589) mesenchymal cell migration(GO:0090497)
0.1 0.5 GO:1904667 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.1 1.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 1.2 GO:0044090 positive regulation of vacuole organization(GO:0044090)
0.1 2.0 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 1.8 GO:1903963 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 1.4 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.1 0.6 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.4 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.5 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 0.6 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 3.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 0.8 GO:0031106 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.1 1.0 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.8 GO:0030262 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.1 1.2 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.1 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.8 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.6 GO:0048714 positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.1 2.1 GO:0018149 peptide cross-linking(GO:0018149)
0.1 0.6 GO:0035092 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.9 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.9 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.9 GO:0030719 P granule organization(GO:0030719)
0.1 1.6 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.1 0.5 GO:0006574 valine catabolic process(GO:0006574)
0.1 0.6 GO:0051673 membrane disruption in other organism(GO:0051673)
0.1 0.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.8 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 1.2 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.1 0.7 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.4 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.9 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 0.9 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 1.6 GO:0001966 thigmotaxis(GO:0001966)
0.1 0.7 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.1 0.8 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.1 4.5 GO:0060048 cardiac muscle contraction(GO:0060048)
0.1 0.3 GO:0071926 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.1 0.5 GO:0034633 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.1 1.6 GO:0051289 protein homotetramerization(GO:0051289)
0.1 0.2 GO:0072020 proximal straight tubule development(GO:0072020)
0.1 1.0 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.7 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 0.6 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 0.3 GO:0010873 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873) triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372) reverse cholesterol transport(GO:0043691)
0.1 0.8 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 1.8 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 1.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.9 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 1.4 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.1 GO:0050787 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.0 1.3 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.2 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 1.2 GO:0051085 'de novo' protein folding(GO:0006458) 'de novo' posttranslational protein folding(GO:0051084) chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.4 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.7 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 1.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 2.8 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.7 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 2.0 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 0.7 GO:0007032 endosome organization(GO:0007032)
0.0 0.8 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 1.3 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.9 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 3.5 GO:0006979 response to oxidative stress(GO:0006979)
0.0 1.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.0 GO:0071711 basement membrane organization(GO:0071711)
0.0 1.0 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.8 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.0 0.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.3 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 1.1 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 1.6 GO:0032200 telomere maintenance(GO:0000723) telomere organization(GO:0032200)
0.0 0.3 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 1.0 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.9 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.6 GO:0019226 transmission of nerve impulse(GO:0019226)
0.0 0.2 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.1 GO:0033292 T-tubule organization(GO:0033292)
0.0 0.6 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.8 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 0.2 GO:0001952 regulation of cell-matrix adhesion(GO:0001952)
0.0 0.7 GO:0043491 protein kinase B signaling(GO:0043491)
0.0 0.1 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.7 GO:0060840 artery development(GO:0060840)
0.0 0.2 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.1 GO:0007141 male meiosis I(GO:0007141)
0.0 0.9 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.3 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.9 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.5 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.9 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.3 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.3 GO:0070972 protein localization to endoplasmic reticulum(GO:0070972)
0.0 0.3 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 3.4 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 0.4 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.4 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 1.4 GO:0017157 regulation of exocytosis(GO:0017157)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.9 2.7 GO:0070545 PeBoW complex(GO:0070545)
0.5 2.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.4 2.5 GO:0035517 PR-DUB complex(GO:0035517)
0.3 1.3 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.3 1.3 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.3 1.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.3 1.0 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.2 1.0 GO:1990909 Wnt signalosome(GO:1990909)
0.2 0.6 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.2 0.7 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.2 2.9 GO:0042555 MCM complex(GO:0042555)
0.1 1.2 GO:0072487 MSL complex(GO:0072487)
0.1 1.8 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.5 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.1 0.8 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.3 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 1.4 GO:0017119 Golgi transport complex(GO:0017119)
0.1 4.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 3.6 GO:0000781 chromosome, telomeric region(GO:0000781)
0.1 1.0 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.8 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.7 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 1.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.7 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.1 0.5 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.3 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 0.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.3 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.1 1.2 GO:0009925 basal plasma membrane(GO:0009925)
0.1 2.4 GO:0005861 troponin complex(GO:0005861)
0.1 0.9 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 7.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 0.5 GO:0016272 prefoldin complex(GO:0016272)
0.1 1.2 GO:0005686 U2 snRNP(GO:0005686) U12-type spliceosomal complex(GO:0005689)
0.1 1.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.5 GO:0043186 P granule(GO:0043186)
0.0 0.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 1.5 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.7 GO:0030057 desmosome(GO:0030057)
0.0 3.4 GO:0000776 kinetochore(GO:0000776)
0.0 0.7 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.0 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.7 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.9 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.3 GO:0098843 postsynaptic endocytic zone(GO:0098843) postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.5 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.6 GO:0005811 lipid particle(GO:0005811)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.0 GO:0004962 endothelin receptor activity(GO:0004962)
0.7 3.5 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.6 2.2 GO:0043998 H2A histone acetyltransferase activity(GO:0043998)
0.5 1.6 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.5 1.6 GO:0043878 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878)
0.5 2.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.5 2.0 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.5 1.4 GO:0004555 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
0.4 1.8 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.3 3.0 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.2 0.9 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.2 1.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 2.8 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 0.9 GO:0004001 adenosine kinase activity(GO:0004001)
0.2 1.3 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2 1.1 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.2 0.7 GO:0033149 FFAT motif binding(GO:0033149)
0.2 1.7 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.2 0.8 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.2 0.8 GO:0009374 biotin binding(GO:0009374)
0.1 0.5 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 1.8 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 0.5 GO:0045547 dehydrodolichyl diphosphate synthase activity(GO:0045547)
0.1 0.9 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 1.0 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 0.9 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.5 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.5 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.1 0.6 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 4.7 GO:0051087 chaperone binding(GO:0051087)
0.1 0.7 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 1.2 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 2.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 4.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 0.7 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 3.3 GO:0019003 GDP binding(GO:0019003)
0.1 0.4 GO:1904121 phosphatidylethanolamine transporter activity(GO:1904121)
0.1 0.6 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.7 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.7 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.9 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.1 1.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.8 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.1 1.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.9 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.4 GO:0016415 octanoyltransferase activity(GO:0016415)
0.1 0.6 GO:0034584 piRNA binding(GO:0034584)
0.1 1.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.4 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.5 GO:0034632 retinol transporter activity(GO:0034632)
0.1 0.9 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.1 0.9 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 0.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.3 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 0.8 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 4.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.1 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 1.3 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 2.7 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.5 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 3.6 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 1.2 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.6 GO:0008143 poly(A) binding(GO:0008143)
0.0 1.7 GO:0005178 integrin binding(GO:0005178)
0.0 7.3 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.3 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.0 1.4 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0004557 alpha-galactosidase activity(GO:0004557)
0.0 0.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.8 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.8 GO:0050661 NADP binding(GO:0050661)
0.0 0.8 GO:0000049 tRNA binding(GO:0000049)
0.0 1.2 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 2.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.5 GO:0098631 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0 1.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 2.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 0.7 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 1.5 PID ARF6 PATHWAY Arf6 signaling events
0.1 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.2 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.9 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.8 PID ATR PATHWAY ATR signaling pathway
0.0 0.8 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 2.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.6 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.8 PID INSULIN PATHWAY Insulin Pathway
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.5 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.3 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.5 PID E2F PATHWAY E2F transcription factor network
0.0 0.4 PID P73PATHWAY p73 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 2.9 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 2.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.2 2.9 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 0.8 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 2.0 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 1.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 0.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.9 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.3 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 3.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.0 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 2.4 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 1.5 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 1.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 0.9 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 0.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.1 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.1 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.2 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.1 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 1.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.7 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins