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PRJEB1986: zebrafish developmental stages transcriptome

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Results for nkx3-2+nkx3.3-2

Z-value: 0.85

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Transcription factors associated with nkx3-2+nkx3.3-2

Gene Symbol Gene ID Gene Info
nkx3-2
ENSDARG00000037639 NK3 homeobox 2
nkx3.3-2
ENSDARG00000069327 NK3 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nkx3.2dr11_v1_chr14_-_215051_2150510.312.0e-01Click!
nkx3.3dr11_v1_chr13_-_40401870_40401870-0.213.8e-01Click!

Activity profile of nkx3-2+nkx3.3-2 motif

Sorted Z-values of nkx3-2+nkx3.3-2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_16636627 4.12 ENSDART00000128811
si:dkey-239j18.3
si:dkey-239j18.3
chr17_+_51746830 2.13 ENSDART00000184230
odc1
ornithine decarboxylase 1
chr23_-_21471022 2.08 ENSDART00000104206
her4.2
hairy-related 4, tandem duplicate 2
chr23_+_25292147 1.97 ENSDART00000131486
pa2g4b
proliferation-associated 2G4, b
chr20_-_25643667 1.83 ENSDART00000137457
si:dkeyp-117h8.4
si:dkeyp-117h8.4
chr6_+_13201358 1.73 ENSDART00000190290
CT009620.1

chr11_+_14333441 1.69 ENSDART00000171969
ptbp1b
polypyrimidine tract binding protein 1b
chr1_-_51710225 1.62 ENSDART00000057601
ENSDART00000152745
snrpb2
small nuclear ribonucleoprotein polypeptide B2
chr10_+_13209580 1.44 ENSDART00000000887
ENSDART00000136932
rassf6
Ras association (RalGDS/AF-6) domain family 6
chr7_+_20917966 1.40 ENSDART00000129161
wrap53
WD repeat containing, antisense to TP53
chr8_-_48847772 1.19 ENSDART00000122458
wrap73
WD repeat containing, antisense to TP73
chr24_+_17005647 1.15 ENSDART00000149149
zfx
zinc finger protein, X-linked
chr6_+_58622831 1.11 ENSDART00000128793
sp7
Sp7 transcription factor
chr5_-_26765188 1.10 ENSDART00000029450
rnf181
ring finger protein 181
chr22_+_9922301 1.05 ENSDART00000105924
blf
bloody fingers
chr4_+_17327704 1.04 ENSDART00000016075
ENSDART00000133160
nup37
nucleoporin 37
chr15_-_35246742 1.03 ENSDART00000131479
mff
mitochondrial fission factor
chr7_+_44715224 0.98 ENSDART00000184630
si:dkey-56m19.5
si:dkey-56m19.5
chr18_-_26781616 0.96 ENSDART00000136776
ENSDART00000076484
kti12
KTI12 chromatin associated homolog
chr3_-_53559581 0.93 ENSDART00000183499
notch3
notch 3
chr1_-_28860732 0.90 ENSDART00000177588
timmdc1
translocase of inner mitochondrial membrane domain containing 1
chr4_+_13931578 0.89 ENSDART00000142466
pphln1
periphilin 1
chr14_-_26392475 0.88 ENSDART00000170614
b4galt7
xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)
chr18_-_20458412 0.88 ENSDART00000012241
kif23
kinesin family member 23
chr9_-_34882516 0.88 ENSDART00000011163
asmtl
acetylserotonin O-methyltransferase-like
chr11_-_5953636 0.87 ENSDART00000140960
ENSDART00000123601
dda1
DET1 and DDB1 associated 1
chr15_-_41245962 0.85 ENSDART00000155359
smco4
single-pass membrane protein with coiled-coil domains 4
chr8_+_25299069 0.82 ENSDART00000114676
gstm.2
glutathione S-transferase mu tandem duplicate 2
chr4_+_45357558 0.81 ENSDART00000150769
si:ch211-162i8.5
si:ch211-162i8.5
chr2_-_51644044 0.81 ENSDART00000157899
dad1
defender against cell death 1
chr15_+_24676905 0.80 ENSDART00000078014
ENSDART00000143137
poldip2
polymerase (DNA-directed), delta interacting protein 2
chr8_+_24281512 0.79 ENSDART00000062845
mmp9
matrix metallopeptidase 9
chr18_-_29977431 0.77 ENSDART00000135357
si:ch211-220f16.2
si:ch211-220f16.2
chr8_+_20455134 0.74 ENSDART00000079618
rexo1
REX1, RNA exonuclease 1 homolog
chr9_-_9225980 0.74 ENSDART00000180301
cbsb
cystathionine-beta-synthase b
chr19_-_31802296 0.73 ENSDART00000103640
hey1
hes-related family bHLH transcription factor with YRPW motif 1
chr3_-_16413606 0.72 ENSDART00000127309
ENSDART00000017172
ENSDART00000136465
eftud2
elongation factor Tu GTP binding domain containing 2
chr12_+_26706745 0.71 ENSDART00000141401
arhgap12b
Rho GTPase activating protein 12b
chr23_-_33558161 0.70 ENSDART00000018301
itga5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr3_-_18384501 0.68 ENSDART00000027630
kdelr2a
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2a
chr18_+_22220656 0.67 ENSDART00000191862
ripor1
RHO family interacting cell polarization regulator 1
chr15_+_888704 0.66 ENSDART00000182796
si:dkey-7i4.9
si:dkey-7i4.9
chr19_+_43604643 0.63 ENSDART00000151168
si:ch211-199g17.9
si:ch211-199g17.9
chr7_-_25930594 0.63 ENSDART00000192834
BX005022.1

chr10_-_29831944 0.62 ENSDART00000063923
ENSDART00000136264
zpr1
ZPR1 zinc finger
chr13_+_12606821 0.62 ENSDART00000140096
ENSDART00000145136
metap1
methionyl aminopeptidase 1
chr1_-_48933 0.61 ENSDART00000171162
ildr1a
immunoglobulin-like domain containing receptor 1a
chr9_-_49829685 0.61 ENSDART00000162271
ttc21b
tetratricopeptide repeat domain 21B
chr16_+_26612401 0.60 ENSDART00000145571
epb41l4b
erythrocyte membrane protein band 4.1 like 4B
chr21_+_4403155 0.58 ENSDART00000161623
HTRA2 (1 of many)
si:dkey-84o3.3
chr5_-_31716713 0.58 ENSDART00000131443
dpm2
dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
chr1_+_16621345 0.57 ENSDART00000149026
pcm1
pericentriolar material 1
chr1_-_28861226 0.57 ENSDART00000075502
timmdc1
translocase of inner mitochondrial membrane domain containing 1
chr5_-_26764880 0.55 ENSDART00000140392
ENSDART00000134728
rnf181
ring finger protein 181
chr21_+_4388489 0.54 ENSDART00000144555
HTRA2 (1 of many)
si:dkey-84o3.3
chr3_-_32603191 0.53 ENSDART00000150997
si:ch73-248e21.7
si:ch73-248e21.7
chr11_-_36474306 0.52 ENSDART00000170678
ENSDART00000123591
usp48
ubiquitin specific peptidase 48
chr18_-_27858123 0.51 ENSDART00000142068
iqcg
IQ motif containing G
chr5_+_1983495 0.50 ENSDART00000179860
CT573103.2

chr10_+_10386435 0.50 ENSDART00000179214
ENSDART00000189799
ENSDART00000193875
sardh
sarcosine dehydrogenase
chr12_+_22580579 0.47 ENSDART00000171725
ENSDART00000192290
capgb
capping protein (actin filament), gelsolin-like b
chr18_-_38216584 0.46 ENSDART00000144622
si:dkey-10o6.2
si:dkey-10o6.2
chr4_-_13931508 0.46 ENSDART00000067174
zcrb1
zinc finger CCHC-type and RNA binding motif 1
chr18_+_16943911 0.46 ENSDART00000157609
si:dkey-8l13.5
si:dkey-8l13.5
chr20_-_438646 0.45 ENSDART00000009196
ufl1
UFM1-specific ligase 1
chr18_-_22094102 0.43 ENSDART00000100904
pard6a
par-6 family cell polarity regulator alpha
chr3_-_53559408 0.43 ENSDART00000073930
notch3
notch 3
chr23_+_12840080 0.42 ENSDART00000081016
ENSDART00000121697
smc1al
structural maintenance of chromosomes 1A, like
chr7_+_54222156 0.42 ENSDART00000165201
ENSDART00000158518
pacsin3
protein kinase C and casein kinase substrate in neurons 3
chr18_+_22174630 0.39 ENSDART00000089549
ripor1
RHO family interacting cell polarization regulator 1
chr1_-_18803919 0.39 ENSDART00000020970
pgm2
phosphoglucomutase 2
chr16_+_27444098 0.39 ENSDART00000157690
invs
inversin
chr11_+_13207898 0.39 ENSDART00000060310
atp5f1b
ATP synthase F1 subunit beta
chr24_-_31223232 0.38 ENSDART00000164155
alg14
ALG14, UDP-N-acetylglucosaminyltransferase subunit
chr16_-_24815091 0.37 ENSDART00000154269
ENSDART00000131025
kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr15_+_15173611 0.35 ENSDART00000155267
si:ch211-149e23.4
si:ch211-149e23.4
chr5_-_42083363 0.35 ENSDART00000162596
cxcl11.5
chemokine (C-X-C motif) ligand 11, duplicate 5
chr13_+_15581270 0.34 ENSDART00000189880
ENSDART00000190067
ENSDART00000041293
mark3a
MAP/microtubule affinity-regulating kinase 3a
chr15_-_36727462 0.34 ENSDART00000085971
nphs1
nephrosis 1, congenital, Finnish type (nephrin)
chr22_+_2830703 0.34 ENSDART00000145463
ENSDART00000144785
si:dkey-20i20.8
si:dkey-20i20.8
chr6_-_39198912 0.32 ENSDART00000077938
c1galt1b
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1b
chr1_+_1789357 0.30 ENSDART00000006449
atp1a1a.2
ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 2
chr24_+_21676921 0.30 ENSDART00000066677
si:ch211-140b10.6
si:ch211-140b10.6
chr7_-_6441865 0.30 ENSDART00000172831
hist1h2a10
histone cluster 1 H2A family member 10
chr7_-_4843401 0.30 ENSDART00000137489
si:dkey-83f18.8
si:dkey-83f18.8
chr2_-_59157790 0.29 ENSDART00000192303
ENSDART00000159362
ftr32
finTRIM family, member 32
chr11_-_12634017 0.29 ENSDART00000158286
ENSDART00000193090
CR450764.1

chr22_-_26514386 0.29 ENSDART00000125628
CR759791.1

chr6_+_374875 0.28 ENSDART00000171698
si:zfos-169g10.3
si:zfos-169g10.3
chr20_+_6773790 0.28 ENSDART00000169966
igfbp3
insulin-like growth factor binding protein 3
chr19_-_3777217 0.28 ENSDART00000160510
si:dkey-206d17.15
si:dkey-206d17.15
chr16_-_13623928 0.27 ENSDART00000164344
si:dkeyp-69b9.6
si:dkeyp-69b9.6
chr25_+_19670273 0.26 ENSDART00000073472
zgc:113426
zgc:113426
chr5_+_61843752 0.26 ENSDART00000130940
CR759879.1
Danio rerio interferon-induced protein with tetratricopeptide repeats 5 (LOC572297), mRNA.
chr16_+_28994709 0.25 ENSDART00000088023
gon4l
gon-4-like (C. elegans)
chr5_-_23117078 0.22 ENSDART00000051529
uprt
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
chr6_-_40038543 0.22 ENSDART00000154792
si:dkey-197j19.6
si:dkey-197j19.6
chr14_-_1200854 0.22 ENSDART00000106672
arl9
ADP-ribosylation factor-like 9
chr4_-_5077158 0.22 ENSDART00000155915
ahcyl2
adenosylhomocysteinase-like 2
chr20_-_30377221 0.21 ENSDART00000126229
rps7
ribosomal protein S7
chr19_+_19989380 0.19 ENSDART00000142841
osbpl3a
oxysterol binding protein-like 3a
chr9_+_32635546 0.18 ENSDART00000189909
rabl3
RAB, member of RAS oncogene family-like 3
chr4_+_71018579 0.18 ENSDART00000186727
si:dkeyp-80d11.10
si:dkeyp-80d11.10
chr20_+_46172649 0.17 ENSDART00000111317
taar13e
trace amine associated receptor 13e
chr6_-_29105727 0.17 ENSDART00000184355
fam69ab
family with sequence similarity 69, member Ab
chr25_+_16356083 0.16 ENSDART00000125925
ENSDART00000125444
tead1a
TEA domain family member 1a
chr22_-_27113332 0.13 ENSDART00000146951
ENSDART00000178855
xpnpep1
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chr17_-_21278582 0.12 ENSDART00000157518
hspa12a
heat shock protein 12A
chr17_+_31742923 0.12 ENSDART00000086696
arhgap5
Rho GTPase activating protein 5
chr17_+_6563307 0.12 ENSDART00000156454
adgrf3a
adhesion G protein-coupled receptor F3a
chr2_-_55797318 0.11 ENSDART00000158147
calr3b
calreticulin 3b
chr12_+_19030391 0.11 ENSDART00000153927
si:ch73-139e5.2
si:ch73-139e5.2
chr17_-_21278846 0.11 ENSDART00000181356
hspa12a
heat shock protein 12A
chr15_-_31027112 0.09 ENSDART00000100185
lgals9l4
lectin, galactoside-binding, soluble, 9 (galectin 9)-like 4
chr7_-_23777445 0.09 ENSDART00000173527
si:ch211-200p22.4
si:ch211-200p22.4
chrM_+_9735 0.07 ENSDART00000093613
mt-co3
cytochrome c oxidase III, mitochondrial
chr8_-_4031121 0.06 ENSDART00000169474
ENSDART00000163754
mtmr3
myotubularin related protein 3
chr21_-_11791909 0.05 ENSDART00000180893
RHOBTB3
si:dkey-6b12.5
chr16_-_16522013 0.02 ENSDART00000160602
nbeal2
neurobeachin-like 2
chr8_+_28547687 0.02 ENSDART00000110291
srxn1
sulfiredoxin 1 homolog (S. cerevisiae)
chr7_+_39688208 0.01 ENSDART00000189682
tbc1d14
TBC1 domain family, member 14
chr15_+_5360407 0.01 ENSDART00000110420
or112-1
odorant receptor, family A, subfamily 112, member 1
chr5_-_8907819 0.00 ENSDART00000188523
adamts12
ADAM metallopeptidase with thrombospondin type 1 motif, 12

Network of associatons between targets according to the STRING database.

First level regulatory network of nkx3-2+nkx3.3-2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0035019 somatic stem cell population maintenance(GO:0035019) symmetric cell division(GO:0098725)
0.3 1.4 GO:0030575 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.3 0.8 GO:0002544 granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
0.2 0.7 GO:0050666 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.2 2.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.2 1.1 GO:0097094 regulation of osteoblast proliferation(GO:0033688) craniofacial suture morphogenesis(GO:0097094)
0.2 0.8 GO:0070987 error-free translesion synthesis(GO:0070987)
0.2 0.9 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.2 0.5 GO:1901052 sarcosine metabolic process(GO:1901052)
0.2 0.6 GO:0070084 protein initiator methionine removal(GO:0070084)
0.1 0.9 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.7 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.1 0.6 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.6 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 2.1 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 0.4 GO:0072003 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.1 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.7 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.4 GO:1990592 IRE1-mediated unfolded protein response(GO:0036498) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.5 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 1.2 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.1 0.2 GO:0001779 natural killer cell differentiation(GO:0001779)
0.1 0.6 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 1.0 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.6 GO:0070193 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0 0.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.3 GO:0014028 notochord formation(GO:0014028)
0.0 0.4 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.8 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.1 GO:0032689 negative regulation of interferon-gamma production(GO:0032689) CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0 0.9 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.3 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.5 GO:0051014 actin filament severing(GO:0051014)
0.0 0.2 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.9 GO:0030166 proteoglycan biosynthetic process(GO:0030166)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.0 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 1.0 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 1.4 GO:0015030 Cajal body(GO:0015030)
0.1 0.6 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 1.6 GO:0005685 U1 snRNP(GO:0005685)
0.1 0.7 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.1 0.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.4 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 0.6 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.7 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.4 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.6 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.9 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.9 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.2 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.7 GO:0008305 integrin complex(GO:0008305)
0.0 4.1 GO:0005764 lysosome(GO:0005764)
0.0 0.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0030623 U5 snRNA binding(GO:0030623)
0.2 2.1 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.2 1.6 GO:0030619 U1 snRNA binding(GO:0030619)
0.2 0.7 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.4 GO:0071568 UFM1 transferase activity(GO:0071568)
0.1 0.7 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.1 0.9 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 0.5 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 0.9 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.1 1.4 GO:0005112 Notch binding(GO:0005112)
0.0 1.0 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.4 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 4.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.4 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 2.1 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.8 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.9 PID AURORA B PATHWAY Aurora B signaling
0.0 1.4 PID NOTCH PATHWAY Notch signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 0.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 2.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 0.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.9 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.9 REACTOME KINESINS Genes involved in Kinesins
0.0 1.4 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.0 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.7 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 2.3 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.6 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.8 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation