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PRJEB1986: zebrafish developmental stages transcriptome

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Results for nkx2.5

Z-value: 0.35

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Transcription factors associated with nkx2.5

Gene Symbol Gene ID Gene Info
ENSDARG00000018004 NK2 homeobox 5
ENSDARG00000116714 NK2 homeobox 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nkx2.5dr11_v1_chr14_+_24241241_24241241-0.455.5e-02Click!

Activity profile of nkx2.5 motif

Sorted Z-values of nkx2.5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_16764751 0.92 ENSDART00000113862
zgc:174154
chr12_-_16636627 0.90 ENSDART00000128811
si:dkey-239j18.3
chr14_+_16036139 0.45 ENSDART00000190733
PRELI domain containing 1a
chr5_+_250078 0.39 ENSDART00000127504
TraB domain containing 2A
chr3_-_13599482 0.39 ENSDART00000166639
Tu translation elongation factor, mitochondrial
chr12_-_17479078 0.39 ENSDART00000079115
3'-phosphoadenosine 5'-phosphosulfate synthase 2b
chr23_+_25292147 0.39 ENSDART00000131486
proliferation-associated 2G4, b
chr12_+_5102670 0.34 ENSDART00000166600
centrosomal protein 55 like
chr20_-_25643667 0.33 ENSDART00000137457
si:dkeyp-117h8.4
chr4_+_37406676 0.32 ENSDART00000130981
si:ch73-134f24.1
chr20_-_26588736 0.32 ENSDART00000134337
exocyst complex component 2
chr8_-_28349859 0.31 ENSDART00000062671
tubulin, alpha 8 like
chr9_+_30294096 0.31 ENSDART00000026551
sushi-repeat containing protein, X-linked
chr6_+_58622831 0.30 ENSDART00000128793
Sp7 transcription factor
chr15_-_35246742 0.30 ENSDART00000131479
mitochondrial fission factor
chr3_-_49514874 0.28 ENSDART00000167179
anti-silencing function 1Ba histone chaperone
chr25_-_11016675 0.27 ENSDART00000099572
mesoderm posterior ab
chr13_-_50614639 0.27 ENSDART00000170527
ventral expressed homeobox
chr17_+_13088594 0.27 ENSDART00000193207
gem (nuclear organelle) associated protein 2
chr10_-_33265566 0.27 ENSDART00000063642
transducin (beta)-like 2
chr6_-_19341184 0.26 ENSDART00000168236
ENSDART00000167674
MIF4G domain containing a
chr15_-_47865063 0.26 ENSDART00000151600
H3 histone, family 3B.1
chr15_+_823437 0.25 ENSDART00000155608
si:dkey-7i4.7
chr6_+_58832155 0.25 ENSDART00000144842
dynactin 2 (p50)
chr9_+_30475563 0.24 ENSDART00000133118
gap junction protein, alpha 5a
chr10_-_29831944 0.24 ENSDART00000063923
ENSDART00000136264
ZPR1 zinc finger
chr7_-_20464133 0.24 ENSDART00000078192
canopy4
chr12_+_20587179 0.24 ENSDART00000170127
arylsulfatase G
chr15_-_17138640 0.24 ENSDART00000080777
mitochondrial ribosomal protein L28
chr19_+_46240171 0.24 ENSDART00000162785
mitogen-activated protein kinase 15
chr7_-_67316903 0.24 ENSDART00000159408
proteasome 26S subunit, non-ATPase 7
chr12_-_13336703 0.24 ENSDART00000134356
LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
chr2_+_30513887 0.24 ENSDART00000137048
membrane-associated ring finger (C3HC4) 6
chr8_-_22558773 0.23 ENSDART00000074309
porcupine O-acyltransferase like
chr4_+_52356485 0.23 ENSDART00000170639
zgc:173705
chr7_+_40638210 0.23 ENSDART00000052236
motor neuron and pancreas homeobox 1
chr12_+_6098713 0.23 ENSDART00000139054
sphingomyelin synthase 1
chr13_-_6218248 0.23 ENSDART00000159052
si:zfos-1056e6.1
chr17_-_28797395 0.22 ENSDART00000134735
sec1 family domain containing 1
chr13_-_28610965 0.22 ENSDART00000043156
cytochrome P450, family 17, subfamily A, polypeptide 1
chr5_+_2002804 0.22 ENSDART00000064088
vitamin K epoxide reductase complex, subunit 1-like 1
chr7_+_24390939 0.22 ENSDART00000087494
ENSDART00000125463
HAUS augmin-like complex, subunit 3
chr16_-_31824525 0.21 ENSDART00000058737
cell division cycle 42, like
chr8_-_45759137 0.20 ENSDART00000123878
peptidylprolyl isomerase Aa (cyclophilin A)
chr11_+_39928828 0.20 ENSDART00000137516
ENSDART00000134082
vesicle-associated membrane protein 3 (cellubrevin)
chr6_+_55428924 0.20 ENSDART00000018270
nuclear receptor coactivator 5
chr20_+_34390196 0.20 ENSDART00000183596
tRNA methyltransferase 1-like
chr20_+_25904199 0.20 ENSDART00000016864
solute carrier family 35, member F6
chr6_+_11990733 0.20 ENSDART00000151075
bromodomain adjacent to zinc finger domain, 2Ba
chr4_+_13901458 0.20 ENSDART00000137549
periphilin 1
chr5_-_26765188 0.20 ENSDART00000029450
ring finger protein 181
chr12_-_44072716 0.20 ENSDART00000162509
si:ch73-329n5.3
chr22_+_25236888 0.19 ENSDART00000037286
zgc:172218
chr7_-_30639385 0.19 ENSDART00000173618
myosin IE, a
chr14_+_31493119 0.19 ENSDART00000006463
PHD finger protein 6
chr4_-_77130289 0.19 ENSDART00000174380

chr3_+_29640837 0.19 ENSDART00000132298
eukaryotic translation initiation factor 3, subunit D
chr3_+_35812040 0.19 ENSDART00000075903
ENSDART00000147712
cytokine receptor-like factor 3
chr12_+_22576404 0.19 ENSDART00000172053
capping protein (actin filament), gelsolin-like b
chr6_+_58832323 0.19 ENSDART00000042595
dynactin 2 (p50)
chr4_-_77125693 0.18 ENSDART00000174256

chr3_-_26805455 0.18 ENSDART00000180648
phosphatidylinositol glycan anchor biosynthesis, class Q
chr4_+_13428993 0.18 ENSDART00000067151
si:dkey-39a18.1
chr8_-_20243389 0.18 ENSDART00000184904
alkaline ceramidase 1
chr5_-_24543526 0.18 ENSDART00000046384
tRNA methyltransferase 2 homolog A
chr3_+_32571929 0.18 ENSDART00000151025
si:ch73-248e21.1
chr15_+_24676905 0.18 ENSDART00000078014
ENSDART00000143137
polymerase (DNA-directed), delta interacting protein 2
chr7_+_16352924 0.18 ENSDART00000158972
metallophosphoesterase domain containing 2a
chr3_-_32079916 0.18 ENSDART00000040900
BCL2 associated X, apoptosis regulator b
chr20_-_53996193 0.18 ENSDART00000004756
heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1
chr20_+_14789305 0.18 ENSDART00000002463
transmembrane p24 trafficking protein 5
chr16_-_17200120 0.18 ENSDART00000147739
glyceraldehyde-3-phosphate dehydrogenase
chr12_+_17201522 0.18 ENSDART00000014536
ENSDART00000152452
renalase, FAD-dependent amine oxidase
chr22_-_19552796 0.18 ENSDART00000148088
ENSDART00000105485
si:dkey-78l4.14
chr1_-_28860732 0.17 ENSDART00000177588
translocase of inner mitochondrial membrane domain containing 1
chr2_-_37280028 0.17 ENSDART00000139459
NAD kinase b
chr19_+_7292654 0.17 ENSDART00000140459
coiled-coil domain containing 127b
chr4_-_77135076 0.17 ENSDART00000174184
zgc:173770
chr12_-_19862912 0.17 ENSDART00000145788
shisa family member 9a
chr6_-_25952848 0.16 ENSDART00000076997
ENSDART00000148748
LIM domain only 4b
chr24_-_23839647 0.16 ENSDART00000125190
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr5_+_47975758 0.16 ENSDART00000097429

chr22_+_2229964 0.16 ENSDART00000112582
zinc finger protein 1161
chr8_+_25893071 0.16 ENSDART00000078161
transmembrane protein 115
chr9_+_8396755 0.16 ENSDART00000043067
zgc:171776
chr22_-_5663354 0.16 ENSDART00000081774
coiled-coil domain containing 51
chr22_-_4892937 0.16 ENSDART00000147002
si:ch73-256j6.4
chr14_-_33297287 0.16 ENSDART00000045555
ENSDART00000138294
ENSDART00000075056
RAB41, member RAS oncogene family
chr18_-_29977431 0.16 ENSDART00000135357
si:ch211-220f16.2
chr11_-_21031773 0.16 ENSDART00000065985
fibromodulin a
chr19_-_29832876 0.16 ENSDART00000005119
eukaryotic translation initiation factor 3, subunit I
chr13_-_31346392 0.15 ENSDART00000134343
ribosomal RNA processing 12 homolog
chr6_-_42036685 0.15 ENSDART00000155174
si:dkeyp-111e5.4
chr2_+_27010439 0.15 ENSDART00000030547
cadherin 7a
chr24_+_1294176 0.15 ENSDART00000106637
si:ch73-134f24.1
chr17_+_46739693 0.15 ENSDART00000097810
Pim proto-oncogene, serine/threonine kinase, related 22
chr11_-_8208464 0.15 ENSDART00000161283
Pim proto-oncogene, serine/threonine kinase, related 203
chr1_-_55118745 0.14 ENSDART00000133915
SERTA domain containing 2a
chr25_+_36152215 0.14 ENSDART00000036147
iroquois homeobox 5b
chr5_-_61638125 0.14 ENSDART00000134314
si:dkey-261j4.3
chr5_+_18047111 0.14 ENSDART00000132164
histone cell cycle regulator a
chr15_-_21155641 0.14 ENSDART00000061098
ENSDART00000046443
si:dkey-105h12.2
chr3_+_39600562 0.14 ENSDART00000134309
ENSDART00000007170
phosphoribosyl pyrophosphate synthetase-associated protein 2
chr22_+_38762693 0.14 ENSDART00000015016
ENSDART00000150187
alkaline phosphatase, intestinal, tandem duplicate 1
chr13_-_32899322 0.13 ENSDART00000133882
rho-associated, coiled-coil containing protein kinase 2a
chr2_+_24352497 0.13 ENSDART00000134909
Pim proto-oncogene, serine/threonine kinase, related 68
chr3_-_111350 0.13 ENSDART00000171887
zgc:110249
chr4_+_33423119 0.13 ENSDART00000189413
zinc finger protein 1065
chr1_+_46598764 0.13 ENSDART00000053240
calcium binding protein 39-like
chr22_+_2598998 0.13 ENSDART00000176665

chr7_-_67248829 0.13 ENSDART00000192442
zinc finger protein 143a
chr25_-_29080063 0.13 ENSDART00000181911
ENSDART00000138087
cytochrome c oxidase subunit Vaa
chr16_-_9675982 0.13 ENSDART00000113724
mal, T cell differentiation protein 2 (gene/pseudogene)
chr3_-_15487111 0.13 ENSDART00000011320
nuclear factor of activated T cells 2 interacting protein
chr17_-_10043273 0.13 ENSDART00000156078
bromodomain adjacent to zinc finger domain, 1A
chr2_-_8609653 0.13 ENSDART00000193354
ENSDART00000189489
ENSDART00000186144
si:ch211-71m22.1
chr13_+_7242916 0.13 ENSDART00000184238
apoptosis-inducing factor, mitochondrion-associated, 2
chr8_-_7440364 0.12 ENSDART00000180659
histone deacetylase 6
chr16_+_33142734 0.12 ENSDART00000138244
rhomboid, veinlet-like 2 (Drosophila)
chr5_+_24543862 0.12 ENSDART00000029699
ATPase H+ transporting V0 subunit a2b
chr8_+_21114338 0.12 ENSDART00000002186
uridine-cytidine kinase 2a
chr17_+_6538733 0.12 ENSDART00000193712
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr4_+_45357558 0.12 ENSDART00000150769
si:ch211-162i8.5
chr7_-_3669868 0.12 ENSDART00000172907
si:ch211-282j17.12
chr22_+_25236657 0.12 ENSDART00000138012
zgc:172218
chr20_-_5369105 0.12 ENSDART00000114316
serine palmitoyltransferase, long chain base subunit 2b
chr17_-_44249538 0.12 ENSDART00000008816
orthodenticle homeobox 2b
chr5_-_39982694 0.12 ENSDART00000138458
Pim proto-oncogene, serine/threonine kinase, related 200
chr7_-_35083585 0.12 ENSDART00000192732
agouti related neuropeptide
chr14_-_16476863 0.11 ENSDART00000089021
calnexin
chr22_+_5663529 0.11 ENSDART00000106141
translation machinery associated 7 homolog
chr24_+_15655233 0.11 ENSDART00000143160
F-box protein 15
chr7_-_59311165 0.11 ENSDART00000171105
meiosis 1 associated protein
chr14_+_49602 0.11 ENSDART00000035581
otopetrin 1
chr13_-_8229977 0.11 ENSDART00000139728
si:ch211-250c4.4
chr8_+_11471350 0.11 ENSDART00000092355
ENSDART00000136184
tight junction protein 2b (zona occludens 2)
chr17_+_30205258 0.11 ENSDART00000076596
ENSDART00000153795
spermatogenesis associated 17
chr1_-_49950643 0.11 ENSDART00000138301
sphingomyelin synthase 2
chr22_+_1330477 0.11 ENSDART00000157567

chr11_-_36474306 0.11 ENSDART00000170678
ENSDART00000123591
ubiquitin specific peptidase 48
chr22_+_25242322 0.11 ENSDART00000134628
si:ch211-226h8.8
chr12_-_26423439 0.11 ENSDART00000113978
synaptopodin 2-like b
chr22_-_18387059 0.11 ENSDART00000007769
testis-specific serine kinase 6
chr6_+_15373153 0.11 ENSDART00000155865
teleost multiple tissue opsin 2a
chr6_+_55285578 0.11 ENSDART00000180183
zgc:109913
chr23_+_22291440 0.11 ENSDART00000185126

chr4_+_73606482 0.10 ENSDART00000150765
si:ch211-165i18.2
chr11_-_34232906 0.10 ENSDART00000162150
large 60S subunit nuclear export GTPase 1
chr7_-_35083184 0.10 ENSDART00000100253
ENSDART00000135250
ENSDART00000173511
agouti related neuropeptide
chr5_-_13564961 0.10 ENSDART00000146827
si:ch211-230g14.3
chr1_+_47178529 0.10 ENSDART00000158432
ENSDART00000074450
ENSDART00000137448
MORC family CW-type zinc finger 3b
chr24_-_26945390 0.10 ENSDART00000123354
male-specific lethal 2 homolog b (Drosophila)
chr10_+_8481660 0.10 ENSDART00000109559

chr11_-_12634017 0.10 ENSDART00000158286
ENSDART00000193090

chr16_+_44906324 0.10 ENSDART00000074960
cd22 molecule
chr12_+_19030391 0.10 ENSDART00000153927
si:ch73-139e5.2
chr15_-_21132480 0.10 ENSDART00000078734
ENSDART00000157481
alpha-2-macroglobulin-like
chr14_+_31493306 0.10 ENSDART00000138341
PHD finger protein 6
chr8_+_48609521 0.10 ENSDART00000060765
natriuretic peptide B
chr16_-_41787421 0.09 ENSDART00000147210
si:dkey-199f5.8
chr7_-_38664947 0.09 ENSDART00000100546
ENSDART00000112405
six-cysteine containing astacin protease 1
chr21_+_19345558 0.09 ENSDART00000184733
heparanase
chr7_+_22585447 0.09 ENSDART00000149144
cholinergic receptor, nicotinic, beta 1 (muscle) like
chr7_-_16562200 0.09 ENSDART00000169093
ENSDART00000173491
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr20_-_46085840 0.09 ENSDART00000133714
trace amine associated receptor 12a
chr6_-_40657653 0.09 ENSDART00000154359
peptidylprolyl isomerase (cyclophilin)-like 1
chr24_-_7587401 0.09 ENSDART00000093163
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr6_+_24817852 0.09 ENSDART00000165609
BarH-like homeobox 2
chr22_+_1481307 0.08 ENSDART00000177429
si:ch211-255f4.2
chr18_+_33675664 0.08 ENSDART00000140043
si:dkey-47k20.8
chr6_-_7726849 0.08 ENSDART00000151511
solute carrier family 25, member 38b
chr16_+_9609721 0.08 ENSDART00000047920
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr5_-_42083363 0.08 ENSDART00000162596
chemokine (C-X-C motif) ligand 11, duplicate 5
chr5_+_43782267 0.08 ENSDART00000130355
nitric oxide synthase 2a, inducible
chr17_-_16342388 0.08 ENSDART00000017930
potassium channel, subfamily K, member 13a
chr16_+_26612401 0.08 ENSDART00000145571
erythrocyte membrane protein band 4.1 like 4B
chr23_-_24148646 0.08 ENSDART00000113598
Rho guanine nucleotide exchange factor (GEF) 19
chr19_-_31372896 0.08 ENSDART00000046609
scinderin
chr19_+_7292445 0.08 ENSDART00000026634
coiled-coil domain containing 127b
chr21_+_27513859 0.08 ENSDART00000065420
phosphofurin acidic cluster sorting protein 1a
chr2_-_51303937 0.08 ENSDART00000164111
si:ch211-215e19.8
chr2_+_42318012 0.07 ENSDART00000138137
finTRIM family, member 8
chr7_-_23777445 0.07 ENSDART00000173527
si:ch211-200p22.4
chr24_-_2917540 0.07 ENSDART00000164776
family with sequence similarity 69, member C
chr11_-_12379359 0.07 ENSDART00000187551
zgc:174353
chr4_+_33225161 0.07 ENSDART00000150851
si:dkey-247i3.5
chr7_+_19817306 0.07 ENSDART00000044425

chr22_+_26793389 0.07 ENSDART00000165381
Pim proto-oncogene, serine/threonine kinase, related 69
chr2_+_33726862 0.07 ENSDART00000146745
si:dkey-31m5.5
chr10_-_40410884 0.07 ENSDART00000150818
trace amine associated receptor 20n
chr11_-_18017287 0.06 ENSDART00000155443
glutamine-rich 1
chr19_-_11966015 0.06 ENSDART00000123409
si:ch1073-296d18.1
chr9_-_34944604 0.06 ENSDART00000140563
ENSDART00000136812
DCN1, defective in cullin neddylation 1, domain containing 2a
chr11_-_12379541 0.06 ENSDART00000171717
zgc:174353
chr14_+_21828993 0.06 ENSDART00000144367
C-terminal binding protein 1
chr1_+_58470287 0.06 ENSDART00000160245
ENSDART00000169945
si:ch73-236c18.7
chr25_-_28674739 0.06 ENSDART00000067073
leucine rich repeat containing 10
chr11_-_12363941 0.06 ENSDART00000192304
zgc:174353
chr15_+_11883804 0.06 ENSDART00000163255
G protein-coupled receptor 184
chr2_-_37280617 0.06 ENSDART00000190458
NAD kinase b

Network of associatons between targets according to the STRING database.

First level regulatory network of nkx2.5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.4 GO:0050427 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 0.2 GO:0061355 Wnt protein secretion(GO:0061355)
0.1 0.2 GO:0030237 female sex determination(GO:0030237) male sex determination(GO:0030238)
0.1 0.2 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 0.3 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.2 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.1 0.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 0.3 GO:0033688 regulation of osteoblast proliferation(GO:0033688) craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0060031 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) mediolateral intercalation(GO:0060031)
0.0 0.2 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.2 GO:0045429 regulation of nitric oxide biosynthetic process(GO:0045428) positive regulation of nitric oxide biosynthetic process(GO:0045429) positive regulation of reactive oxygen species biosynthetic process(GO:1903428) positive regulation of nitric oxide metabolic process(GO:1904407)
0.0 0.2 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.0 0.4 GO:0030719 P granule organization(GO:0030719)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:1905072 cardiac jelly development(GO:1905072)
0.0 0.1 GO:0051182 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.3 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.1 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343) positive regulation of feeding behavior(GO:2000253)
0.0 0.2 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.2 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.3 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.0 0.1 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.1 GO:0035994 response to muscle stretch(GO:0035994)
0.0 0.2 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.2 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.3 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.1 GO:0044211 CTP salvage(GO:0044211)
0.0 0.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.1 GO:0031282 regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.3 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
0.0 0.0 GO:0021557 oculomotor nerve development(GO:0021557)
0.0 0.1 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.0 0.1 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.0 0.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.2 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.3 GO:0032797 SMN complex(GO:0032797)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.0 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.5 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 0.5 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.2 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.2 GO:0031782 type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.1 0.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.2 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.1 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903) acetylspermidine deacetylase activity(GO:0047611)
0.0 0.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0070122 isopeptidase activity(GO:0070122)
0.0 1.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.0 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0048038 quinone binding(GO:0048038)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.1 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)