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PRJEB1986: zebrafish developmental stages transcriptome

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Results for nkx2.2b

Z-value: 0.44

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Transcription factors associated with nkx2.2b

Gene Symbol Gene ID Gene Info
ENSDARG00000101549 NK2 homeobox 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nkx2.2bdr11_v1_chr20_+_48782068_487820680.743.1e-04Click!

Activity profile of nkx2.2b motif

Sorted Z-values of nkx2.2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_16595406 1.63 ENSDART00000166798
si:dkey-239j18.2
chr12_-_16595177 1.57 ENSDART00000133962
si:dkey-239j18.2
chr1_-_55248496 1.01 ENSDART00000098615
nanos homolog 3
chr2_-_10877228 0.92 ENSDART00000138718
ENSDART00000034246
cell division cycle 7 homolog (S. cerevisiae)
chr12_+_6002715 0.91 ENSDART00000114961
si:ch211-131k2.3
chr9_-_33063083 0.80 ENSDART00000048550
si:ch211-125e6.5
chr3_-_16000168 0.68 ENSDART00000160628
NME/NM23 nucleoside diphosphate kinase 3
chr1_+_5485799 0.67 ENSDART00000022307
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr3_-_15999501 0.67 ENSDART00000160668
NME/NM23 nucleoside diphosphate kinase 3
chr12_-_10476448 0.66 ENSDART00000106172
Rac family small GTPase 1a
chr18_+_37272568 0.66 ENSDART00000132749
transmembrane protein 123
chr4_+_5333988 0.63 ENSDART00000129398
ENSDART00000163850
ENSDART00000067374
ENSDART00000150780
ENSDART00000150493
ENSDART00000150306
APEX nuclease (multifunctional DNA repair enzyme) 1
chr23_-_19827411 0.63 ENSDART00000187964
HAUS augmin-like complex, subunit 7
chr6_+_13201358 0.60 ENSDART00000190290

chr6_-_19341184 0.60 ENSDART00000168236
ENSDART00000167674
MIF4G domain containing a
chr6_+_22326624 0.59 ENSDART00000020333
ribonucleic acid export 1
chr4_-_16451375 0.59 ENSDART00000192700
ENSDART00000128835
wu:fc23c09
chr7_+_21275152 0.58 ENSDART00000173612
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr12_-_4301234 0.58 ENSDART00000152377
ENSDART00000152521
carbonic anhydrase XVb
chr20_+_2739804 0.57 ENSDART00000152655
synaptotagmin binding, cytoplasmic RNA interacting protein
chr1_+_30723380 0.56 ENSDART00000127943
ENSDART00000062628
ENSDART00000127670
bora, aurora kinase A activator
chr18_-_35407695 0.56 ENSDART00000191845
ENSDART00000141703
small nuclear ribonucleoprotein polypeptide A
chr21_+_15603597 0.55 ENSDART00000138626
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b
chr25_+_28589669 0.55 ENSDART00000193901
transmembrane protein 17
chr23_+_38245610 0.55 ENSDART00000191386
zinc finger protein 217
chr11_-_25257595 0.54 ENSDART00000123567
snail family zinc finger 1a
chr22_+_2229964 0.54 ENSDART00000112582
zinc finger protein 1161
chr11_-_30636163 0.53 ENSDART00000140516
zgc:153665
chr7_-_22790630 0.53 ENSDART00000173496
si:ch211-15b10.6
chr21_-_36619599 0.52 ENSDART00000065208
NOP16 nucleolar protein homolog (yeast)
chr4_+_5196469 0.52 ENSDART00000067386
RAD51 associated protein 1
chr13_-_30996072 0.51 ENSDART00000181661
WDFY family member 4
chr15_+_37589698 0.50 ENSDART00000076066
ENSDART00000153894
ENSDART00000156298
lin-37 DREAM MuvB core complex component
chr16_+_20915319 0.49 ENSDART00000079383
homeobox A9b
chr3_-_27647845 0.48 ENSDART00000151625
si:ch211-157c3.4
chr7_-_26518086 0.48 ENSDART00000058913
eukaryotic translation initiation factor 4A1A
chr20_+_2739531 0.48 ENSDART00000152269
synaptotagmin binding, cytoplasmic RNA interacting protein
chr2_-_37956768 0.48 ENSDART00000034595
cerebellin 10
chr4_+_28356606 0.47 ENSDART00000192995
si:ch73-263o4.4
chr14_+_10624911 0.47 ENSDART00000131295
nucleoporin 62 like
chr4_+_33225161 0.46 ENSDART00000150851
si:dkey-247i3.5
chr4_-_16876281 0.46 ENSDART00000016690
ENSDART00000044005
ENSDART00000042874
ENSDART00000125762
ENSDART00000185974
thymopoietin a
chr8_-_30779101 0.46 ENSDART00000062229
purinergic receptor P2X, ligand-gated ion channel, 7
chr4_+_5334202 0.45 ENSDART00000150409
APEX nuclease (multifunctional DNA repair enzyme) 1
chr18_-_27316599 0.45 ENSDART00000028294
zgc:56106
chr4_-_12477224 0.45 ENSDART00000027756
ENSDART00000182706
ENSDART00000127150
Rho guanine nucleotide exchange factor (GEF) 39
chr18_+_26428829 0.45 ENSDART00000190779
ENSDART00000193226
ENSDART00000110746
Bloom syndrome, RecQ helicase-like
chr6_+_13083146 0.45 ENSDART00000172158
trans-L-3-hydroxyproline dehydratase
chr17_+_19481049 0.45 ENSDART00000024194
kinesin family member 11
chr22_-_21676364 0.44 ENSDART00000183668
transducin like enhancer of split 2b
chr4_-_20081621 0.44 ENSDART00000024647
DENN/MADD domain containing 6B
chr19_-_22328154 0.44 ENSDART00000090464
si:ch73-196l6.5
chr5_-_26323137 0.43 ENSDART00000133823
ARVCF, delta catenin family member b
chr16_+_40340523 0.43 ENSDART00000102571
methyltransferase like 6
chr9_+_21722733 0.43 ENSDART00000102021
SRY (sex determining region Y)-box 1a
chr15_-_20468302 0.42 ENSDART00000018514
deltaC
chr25_+_10485103 0.42 ENSDART00000104576
proteasome 26S subunit, non-ATPase 13
chr21_-_14826066 0.41 ENSDART00000067001
nucleolar complex associated 4 homolog
chr16_-_14248892 0.41 ENSDART00000090329
ring finger protein 115
chr14_-_33297287 0.41 ENSDART00000045555
ENSDART00000138294
ENSDART00000075056
RAB41, member RAS oncogene family
chr14_+_14043793 0.41 ENSDART00000164376
Ras-related GTP binding A
chr20_+_51833030 0.41 ENSDART00000074330
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A
chr19_+_42231431 0.41 ENSDART00000102698
jumping translocation breakpoint
chr10_-_6494070 0.41 ENSDART00000171320
decapping mRNA 2
chr14_+_45608576 0.40 ENSDART00000173248
si:ch211-276i12.11
chr4_+_6032640 0.40 ENSDART00000157487
transcription factor EC
chr12_+_36413886 0.40 ENSDART00000126325
si:ch211-250n8.1
chr21_+_19547806 0.40 ENSDART00000159707
ENSDART00000184869
ENSDART00000181321
ENSDART00000058487
ENSDART00000058485
retinoic acid induced 14
chr5_+_28497956 0.40 ENSDART00000191935
notochord formation related
chr7_-_71585065 0.40 ENSDART00000128678
methyltransferase like 4
chr14_-_26392475 0.39 ENSDART00000170614
xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)
chr6_+_18544791 0.39 ENSDART00000167463
ENSDART00000169599
ATPase family, AAA domain containing 5b
chr9_-_18911608 0.39 ENSDART00000138785
si:dkey-239h2.3
chr10_+_44984946 0.39 ENSDART00000182520
H2A histone family, member Vb
chr17_-_10000339 0.39 ENSDART00000162893
sorting nexin 6
chr6_+_49255706 0.39 ENSDART00000156866
si:dkey-183k8.2
chr21_-_3007412 0.39 ENSDART00000190839
zgc:86839
chr2_+_38226145 0.39 ENSDART00000159396
si:ch211-14a17.11
chr3_-_34136778 0.38 ENSDART00000131951
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr17_-_26610814 0.38 ENSDART00000133402
ENSDART00000016608
mitochondrial ribosomal protein L57
chr14_-_25956804 0.38 ENSDART00000135627
ENSDART00000146022
ENSDART00000039660
secreted protein, acidic, cysteine-rich (osteonectin)
chr13_-_33317323 0.37 ENSDART00000110295
ENSDART00000144848
ENSDART00000136701
transmembrane protein 234
chr22_-_4892937 0.37 ENSDART00000147002
si:ch73-256j6.4
chr17_+_6538733 0.37 ENSDART00000193712
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr5_-_55914268 0.37 ENSDART00000014049
WD repeat domain 36
chr14_-_10617923 0.37 ENSDART00000133723
ENSDART00000131939
ENSDART00000136649
si:dkey-92i17.2
chr7_-_8309505 0.36 ENSDART00000182530
coagulation factor XIII, A1 polypeptide b
chr13_+_33304187 0.36 ENSDART00000075826
ENSDART00000145295
doublecortin domain containing 2B
chr7_-_67316903 0.36 ENSDART00000159408
proteasome 26S subunit, non-ATPase 7
chr18_-_22735002 0.36 ENSDART00000023721
nudix hydrolase 21
chr7_+_65296901 0.35 ENSDART00000162693
ENSDART00000161609
bolA family member 3
chr10_-_44924289 0.35 ENSDART00000171267
tubulin, alpha 7 like
chr3_-_26805455 0.35 ENSDART00000180648
phosphatidylinositol glycan anchor biosynthesis, class Q
chr4_-_5333971 0.35 ENSDART00000067375
O-sialoglycoprotein endopeptidase
chr22_-_29922872 0.35 ENSDART00000020249
dual specificity phosphatase 5
chr2_-_10632431 0.35 ENSDART00000122709
metal response element binding transcription factor 2
chr1_+_8534698 0.34 ENSDART00000021504
Smith-Magenis syndrome chromosome region, candidate 8b
chr7_-_35083585 0.34 ENSDART00000192732
agouti related neuropeptide
chr24_+_41989108 0.34 ENSDART00000169725
zinc finger and BTB domain containing 14
chr12_+_19138452 0.33 ENSDART00000141346
ENSDART00000066397
PHD finger protein 5A
chr18_-_14691727 0.33 ENSDART00000010129
peptide deformylase, mitochondrial
chr11_+_42422371 0.33 ENSDART00000163780
DENN/MADD domain containing 6Aa
chr7_+_37742299 0.33 ENSDART00000143300
bromodomain containing 7
chr9_+_6255682 0.32 ENSDART00000149827
UDP-glucuronate decarboxylase 1
chr25_+_19008497 0.32 ENSDART00000104420
SAMM50 sorting and assembly machinery component
chr23_+_19813677 0.32 ENSDART00000139192
ENSDART00000142308
emerin (Emery-Dreifuss muscular dystrophy)
chr4_+_38103421 0.31 ENSDART00000164164
zinc finger protein 1016
chr20_+_25712276 0.31 ENSDART00000121585
ENSDART00000185772
centrosomal protein 135
chr4_+_69823638 0.31 ENSDART00000165786
zinc finger protein 1087
chr11_+_1565806 0.31 ENSDART00000137479
v-myb avian myeloblastosis viral oncogene homolog-like 2b
chr10_-_25343521 0.31 ENSDART00000166348
ENSDART00000009477
chaperonin containing TCP1, subunit 8 (theta)
chr3_+_12829566 0.31 ENSDART00000157672
si:ch211-8c17.2
chr15_+_24746444 0.31 ENSDART00000032306
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1
chr5_-_17601759 0.31 ENSDART00000138387
si:ch211-130h14.6
chr6_-_42377307 0.31 ENSDART00000129302
ER membrane protein complex subunit 3
chr25_-_16755340 0.31 ENSDART00000124729
ENSDART00000110859
RIB43A domain with coiled-coils 2
chr17_-_33412868 0.30 ENSDART00000187521

chr13_+_36595618 0.30 ENSDART00000022684
cornichon family AMPA receptor auxiliary protein 1
chr16_+_3185541 0.30 ENSDART00000024088
WD repeat domain 21
chr7_-_35083184 0.29 ENSDART00000100253
ENSDART00000135250
ENSDART00000173511
agouti related neuropeptide
chr1_-_46832880 0.29 ENSDART00000142406
si:ch73-160h15.3
chr7_+_31132588 0.29 ENSDART00000173702
tight junction protein 1a
chr2_+_26498446 0.29 ENSDART00000078412
ribosomal protein S8a
chr16_+_23913943 0.29 ENSDART00000175404
ENSDART00000129525
apolipoprotein A-IV b, tandem duplicate 1
chr5_+_63390315 0.29 ENSDART00000124616
RAB14, member RAS oncogene family
chr24_+_5935377 0.29 ENSDART00000191989
ENSDART00000185932
ENSDART00000131768
abl-interactor 1a
chr5_-_52752514 0.29 ENSDART00000190162
family with sequence similarity 189, member A2
chr8_-_40205712 0.29 ENSDART00000158927
anaphase promoting complex subunit 5
chr15_-_16323750 0.29 ENSDART00000028500
nucleoredoxin
chr12_-_8511185 0.28 ENSDART00000179910

chr22_-_20720427 0.28 ENSDART00000105532
ornithine decarboxylase antizyme 1a
chr23_-_4225830 0.28 ENSDART00000170455
AAR2 splicing factor homolog (S. cerevisiae)
chr12_-_1031970 0.28 ENSDART00000105292
polymerase (RNA) III (DNA directed) polypeptide E
chr15_+_31526225 0.28 ENSDART00000154456
WD40 repeat domain 95
chr17_-_20228610 0.28 ENSDART00000125758
early B cell factor 3b
chr20_+_492529 0.27 ENSDART00000141709

chr11_+_3308656 0.27 ENSDART00000082458
SAP domain containing ribonucleoprotein
chr22_+_2100774 0.27 ENSDART00000106436
si:dkey-1b17.9
chr3_+_60716904 0.27 ENSDART00000168280
forkhead box J1a
chr3_+_39579393 0.26 ENSDART00000055170
ceroid-lipofuscinosis, neuronal 3
chr22_+_22303053 0.26 ENSDART00000129975
secretory carrier membrane protein 4
chr3_-_26806032 0.26 ENSDART00000143710
phosphatidylinositol glycan anchor biosynthesis, class Q
chr2_-_53525896 0.26 ENSDART00000057053
im:7138239
chr6_-_8465656 0.26 ENSDART00000178887
si:dkey-217d24.6
chr18_-_40481028 0.26 ENSDART00000134177
zgc:101040
chr14_+_22132896 0.26 ENSDART00000138274
cyclin G1
chr3_-_15487111 0.26 ENSDART00000011320
nuclear factor of activated T cells 2 interacting protein
chr2_-_24402341 0.26 ENSDART00000155442
ENSDART00000088572
zgc:154006
chr4_-_32471434 0.26 ENSDART00000152013
ENSDART00000183621
zinc finger protein 1085
chr6_-_7439490 0.25 ENSDART00000188825
FK506 binding protein 11
chr14_+_22132388 0.25 ENSDART00000109065
cyclin G1
chr14_-_45604667 0.25 ENSDART00000167016
si:ch211-276i12.9
chr7_-_67317119 0.25 ENSDART00000183915
proteasome 26S subunit, non-ATPase 7
chr25_-_29134000 0.25 ENSDART00000172027
ENSDART00000190447
poly (ADP-ribose) polymerase family, member 6b
chr8_-_18367736 0.25 ENSDART00000061679
DNA methyltransferase 1 associated protein 1
chr11_+_24900123 0.25 ENSDART00000044987
ENSDART00000148023
translocase of inner mitochondrial membrane 17 homolog A (yeast)
chr2_-_22530969 0.25 ENSDART00000159641
zinc finger protein 644a
chr16_+_5926520 0.25 ENSDART00000162229
unc-51 like kinase 4
chr14_-_21097574 0.24 ENSDART00000186803
ring finger protein 20, E3 ubiquitin protein ligase
chr4_+_26449406 0.24 ENSDART00000183291

chr14_+_12169979 0.24 ENSDART00000129953
ras homolog gene family, member Gd
chr3_-_7524363 0.24 ENSDART00000162970
zinc finger protein 1001
chr12_+_36109507 0.24 ENSDART00000175409
mitogen-activated protein kinase kinase 6
chr7_-_38087865 0.24 ENSDART00000052366
CCAAT/enhancer binding protein (C/EBP), alpha
chr19_+_627899 0.24 ENSDART00000148508
telomerase reverse transcriptase
chr24_-_30263301 0.24 ENSDART00000162328
sorting nexin 7
chr2_-_3038904 0.24 ENSDART00000186795
guanylate kinase 1a
chr13_-_22699024 0.24 ENSDART00000016946
glutamate dehydrogenase 1a
chr6_+_27923054 0.24 ENSDART00000136833
ENSDART00000145533
centrosomal protein 63
chr4_+_59234719 0.23 ENSDART00000170724
ENSDART00000192143
ENSDART00000109914
zinc finger protein 1086
chr10_-_27197044 0.23 ENSDART00000137928
autism susceptibility candidate 2a
chr5_-_67499279 0.23 ENSDART00000128050
si:dkey-251i10.3
chr2_-_21618629 0.23 ENSDART00000027587
v-ral simian leukemia viral oncogene homolog Ab (ras related)
chr23_+_1078072 0.23 ENSDART00000159263
ENSDART00000053527
solute carrier family 34 (type II sodium/phosphate cotransporter), member 2b
chr21_+_25793970 0.23 ENSDART00000101217
zgc:136892
chr6_-_13408680 0.23 ENSDART00000151566
formin-like 2b
chr4_-_41269844 0.23 ENSDART00000186177

chr14_-_42997145 0.23 ENSDART00000172801
protocadherin 10b
chr4_+_62184754 0.23 ENSDART00000168844
si:dkeyp-35e5.9
chr5_-_28052883 0.23 ENSDART00000188791
zgc:113436
chr15_-_684911 0.22 ENSDART00000161685
zgc:171901
chr12_+_29236274 0.22 ENSDART00000006505
mix-type homeobox gene 2
chr11_+_31285127 0.22 ENSDART00000160154
si:dkey-238i5.2
chr2_+_22531185 0.22 ENSDART00000171959
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr2_+_2967255 0.22 ENSDART00000167649
ENSDART00000166449
phosphoinositide-3-kinase, regulatory subunit 3a (gamma)
chr6_+_55212928 0.22 ENSDART00000083668
mannosidase beta like
chr5_+_3927989 0.22 ENSDART00000030125
zinc finger, HIT-type containing 3
chr7_-_44704910 0.22 ENSDART00000037850
dynein, cytoplasmic 1, light intermediate chain 2
chr3_+_18807524 0.22 ENSDART00000055757
transportin 2 (importin 3, karyopherin beta 2b)
chr16_-_45042236 0.22 ENSDART00000058383
transmembrane protein 147
chr11_-_7411436 0.21 ENSDART00000167312
adhesion G protein-coupled receptor L4
chr1_+_33328857 0.21 ENSDART00000137151
matrix-remodelling associated 5a
chr18_-_43866001 0.21 ENSDART00000150218
trehalase (brush-border membrane glycoprotein)
chr10_-_41302841 0.21 ENSDART00000020297
ENSDART00000160174
ENSDART00000183850
ENSDART00000169493
BRF2, RNA polymerase III transcription initiation factor
chr15_-_37589600 0.21 ENSDART00000154641
proline and serine rich 3
chr13_+_8840772 0.21 ENSDART00000059321
epithelial cell adhesion molecule
chr12_+_30726425 0.21 ENSDART00000153275
solute carrier family 35, member F3a
chr9_+_55056310 0.21 ENSDART00000047080
G protein-coupled receptor 143
chr6_-_13200585 0.21 ENSDART00000185321
eukaryotic translation elongation factor 1 beta 2
chr2_-_1514001 0.21 ENSDART00000057736
complement component 8, beta polypeptide

Network of associatons between targets according to the STRING database.

First level regulatory network of nkx2.2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.4 GO:2000425 regulation of apoptotic cell clearance(GO:2000425)
0.1 1.0 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.4 GO:1990120 messenger ribonucleoprotein complex assembly(GO:1990120)
0.1 1.4 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 0.5 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.1 0.3 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.1 0.4 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.1 0.3 GO:0060296 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.1 1.3 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 0.5 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.2 GO:0007571 age-dependent general metabolic decline(GO:0007571)
0.1 0.6 GO:0008343 adult feeding behavior(GO:0008343) positive regulation of feeding behavior(GO:2000253)
0.1 0.3 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 0.2 GO:0015074 DNA integration(GO:0015074)
0.1 0.4 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.3 GO:0090387 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.1 0.2 GO:0005991 trehalose metabolic process(GO:0005991)
0.1 0.2 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 0.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.2 GO:0021693 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698)
0.1 0.3 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.7 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.9 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 0.4 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 0.4 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.2 GO:0003156 regulation of organ formation(GO:0003156)
0.1 0.9 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 1.1 GO:0080111 DNA demethylation(GO:0080111)
0.1 0.5 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.5 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.3 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.1 GO:1902410 mitotic cytokinetic process(GO:1902410) mitotic cleavage furrow formation(GO:1903673)
0.0 0.3 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:0007414 axonal defasciculation(GO:0007414)
0.0 0.1 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
0.0 0.5 GO:0033198 response to ATP(GO:0033198)
0.0 0.3 GO:0015809 arginine transport(GO:0015809)
0.0 0.1 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 0.4 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.2 GO:0045056 transcytosis(GO:0045056)
0.0 0.2 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.0 0.3 GO:0006478 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.2 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.9 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.1 GO:0006953 acute-phase response(GO:0006953)
0.0 0.2 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.0 0.2 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.6 GO:0008354 germ cell migration(GO:0008354)
0.0 0.3 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.6 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 0.7 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.5 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.2 GO:0021794 thalamus development(GO:0021794)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.4 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.8 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.0 0.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.6 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.2 GO:0009146 dGTP catabolic process(GO:0006203) purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dGTP metabolic process(GO:0046070)
0.0 0.1 GO:0031284 regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.6 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0045901 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.3 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.0 0.3 GO:0032438 melanosome organization(GO:0032438)
0.0 0.2 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.3 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.4 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.5 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.1 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.0 0.2 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.4 GO:0019835 cytolysis(GO:0019835)
0.0 0.3 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.2 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.1 GO:0051225 spindle assembly(GO:0051225)
0.0 0.2 GO:0009303 rRNA transcription(GO:0009303) swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.0 0.1 GO:0006691 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0003139 secondary heart field specification(GO:0003139)
0.0 0.5 GO:0006405 RNA export from nucleus(GO:0006405)
0.0 0.2 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.8 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.2 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.1 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.0 0.2 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.4 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.4 GO:0000281 mitotic cytokinesis(GO:0000281)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0030689 Noc complex(GO:0030689)
0.1 0.4 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 0.4 GO:0042382 paraspeckles(GO:0042382)
0.1 1.0 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.4 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.2 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 0.6 GO:0070652 HAUS complex(GO:0070652)
0.1 0.6 GO:0035060 brahma complex(GO:0035060)
0.1 0.5 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 0.4 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.3 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.3 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0070743 interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.0 0.6 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 1.0 GO:0043186 P granule(GO:0043186)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.0 0.6 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.3 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.2 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 4.0 GO:0005764 lysosome(GO:0005764)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.5 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0008311 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.2 0.6 GO:0031782 type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.1 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.3 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.7 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.1 1.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.4 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 0.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.2 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.1 0.4 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.3 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 0.2 GO:0004555 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
0.1 0.2 GO:0072545 tyrosine binding(GO:0072545)
0.1 0.6 GO:0030619 U1 snRNA binding(GO:0030619)
0.1 0.3 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.6 GO:0008494 translation activator activity(GO:0008494)
0.1 0.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 1.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.4 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.1 0.5 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.3 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.4 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.5 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0019972 interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.3 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.1 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 0.6 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.1 GO:0005549 odorant binding(GO:0005549)
0.0 0.4 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.5 GO:0070122 isopeptidase activity(GO:0070122)
0.0 0.4 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.2 GO:0016793 dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793)
0.0 0.1 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 3.4 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.3 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.2 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.2 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.1 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.6 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.3 GO:0004860 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.4 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.5 PID ATM PATHWAY ATM pathway
0.0 0.6 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.5 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.4 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 1.1 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.0 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.6 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.2 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.6 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.2 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.5 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.9 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres