Project

PRJEB1986: zebrafish developmental stages transcriptome

Navigation
Downloads

Results for nkx2.2a

Z-value: 0.74

Motif logo

Transcription factors associated with nkx2.2a

Gene Symbol Gene ID Gene Info
ENSDARG00000053298 NK2 homeobox 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nkx2.2adr11_v1_chr17_-_42213822_42213822-0.681.3e-03Click!

Activity profile of nkx2.2a motif

Sorted Z-values of nkx2.2a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_32838110 2.23 ENSDART00000158077
arrestin 3b, retinal (X-arrestin)
chr25_-_7974494 1.65 ENSDART00000171446
histidine ammonia-lyase
chr7_+_50849142 1.62 ENSDART00000073806
procollagen C-endopeptidase enhancer b
chr22_+_20720808 1.31 ENSDART00000171321
si:dkey-211f22.5
chr19_+_40856807 1.30 ENSDART00000139083
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr24_-_7699356 1.24 ENSDART00000013117
synaptotagmin Vb
chr20_-_34090740 1.06 ENSDART00000062539
ENSDART00000008140
phosducin b
chr14_+_32837914 1.05 ENSDART00000158888
arrestin 3b, retinal (X-arrestin)
chr16_-_11798994 1.02 ENSDART00000135408
cornifelin
chr9_-_22158784 1.02 ENSDART00000167850
crystallin, gamma M2d14
chr19_-_12315693 1.00 ENSDART00000151158
neurocalcin delta b
chr9_-_22158325 1.00 ENSDART00000114568
crystallin, gamma M2d16
chr4_-_72609735 0.97 ENSDART00000174299
ENSDART00000159227
si:cabz01054394.6
chr12_-_19865585 0.93 ENSDART00000066386
shisa family member 9a
chr1_+_15137901 0.93 ENSDART00000111475
protocadherin 7a
chr19_-_12322356 0.92 ENSDART00000016128
neurocalcin delta b
chr5_+_54685175 0.92 ENSDART00000115016
pro-melanin-concentrating hormone, like
chr6_+_49255706 0.91 ENSDART00000156866
si:dkey-183k8.2
chr7_-_38698583 0.91 ENSDART00000173900
ENSDART00000126737
CD59 molecule (CD59 blood group)
chr2_+_5948534 0.89 ENSDART00000124324
ENSDART00000176461
solute carrier family 1 (glutamate transporter), member 7a
chr13_+_47710434 0.89 ENSDART00000188724
transmembrane protein 87B
chr9_-_9998087 0.88 ENSDART00000124423
UDP glucuronosyltransferase 1 family a, b
chr5_+_72087619 0.86 ENSDART00000062885
oxytocin
chr19_+_9344171 0.85 ENSDART00000133447
ENSDART00000104622
si:ch211-288g17.4
chr12_-_3237561 0.83 ENSDART00000164665
si:ch1073-13h15.3
chr11_-_11518469 0.77 ENSDART00000104254
keratin 15
chr5_-_23277939 0.75 ENSDART00000003514
proteolipid protein 1b
chr25_+_20077225 0.74 ENSDART00000136543
troponin I4b, tandem duplicate 1
chr6_+_4872883 0.74 ENSDART00000186730
ENSDART00000092290
ENSDART00000151674
protocadherin 9
chr5_-_47727819 0.73 ENSDART00000165249
cytochrome c oxidase, subunit VIIc
chr20_-_30920356 0.71 ENSDART00000022951
kinesin family member 25
chr12_+_16440708 0.69 ENSDART00000113810
ankyrin repeat domain 1b (cardiac muscle)
chr2_-_15318786 0.69 ENSDART00000135851
trans-2,3-enoyl-CoA reductase-like 2b
chr1_-_22735924 0.68 ENSDART00000134831
prominin 1 b
chr23_-_39784368 0.68 ENSDART00000110282
si:ch211-286f9.2
chr11_-_11471857 0.66 ENSDART00000030103
keratin 94
chr7_-_13884610 0.65 ENSDART00000006897
retinaldehyde binding protein 1a
chr21_-_42055872 0.65 ENSDART00000144767
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr8_+_28065803 0.65 ENSDART00000178481
potassium voltage-gated channel, Shal-related subfamily, member 3
chr13_-_23270576 0.63 ENSDART00000132828
si:dkey-103j14.5
chr2_-_24269911 0.63 ENSDART00000099532
myosin heavy chain 7
chr22_-_8006342 0.62 ENSDART00000162028
sc:d217
chr19_+_37848830 0.61 ENSDART00000042276
ENSDART00000180872
neurexophilin 1
chr1_-_9231952 0.60 ENSDART00000166515
si:dkeyp-57d7.4
chr16_+_30301539 0.59 ENSDART00000186018

chr20_-_34750045 0.58 ENSDART00000186130
zinc finger protein 395b
chr6_+_36795225 0.57 ENSDART00000171504
si:ch73-29l19.1
chr1_+_55662491 0.57 ENSDART00000152386
adhesion G protein-coupled receptor E8
chr5_-_30380593 0.57 ENSDART00000148039
sorting nexin 19a
chr8_-_13823091 0.57 ENSDART00000177174
ENSDART00000137021
calcium binding protein 4
chr12_-_25150239 0.55 ENSDART00000038415
ENSDART00000135368
ras homolog family member Q
chr13_+_28675686 0.55 ENSDART00000027213
internexin neuronal intermediate filament protein, alpha a
chr23_+_6795709 0.55 ENSDART00000149136
si:ch211-117c9.5
chr6_+_21395051 0.54 ENSDART00000017774
calcium channel, voltage-dependent, gamma subunit 5a
chr19_-_10656667 0.54 ENSDART00000081379
ENSDART00000151456
ENSDART00000143271
ENSDART00000182126
oleoyl-ACP hydrolase
chr25_-_32311048 0.53 ENSDART00000181806
ENSDART00000086334

chr9_-_11560427 0.53 ENSDART00000127942
ENSDART00000061442
crystallin, beta A2b
chr9_+_2762270 0.53 ENSDART00000123342
ENSDART00000001795
ENSDART00000177563
sp3a transcription factor
chr8_-_1698155 0.53 ENSDART00000186159

chr8_-_39739627 0.52 ENSDART00000135422
ENSDART00000067844
si:ch211-170d8.5
chr13_-_29424454 0.51 ENSDART00000026765
solute carrier family 18 (vesicular acetylcholine transporter), member 3a
chr7_+_41295974 0.50 ENSDART00000173568
ENSDART00000173544
si:dkey-86l18.10
chr6_-_54121035 0.50 ENSDART00000183970
tumor suppressor candidate 2a
chr15_-_30714130 0.50 ENSDART00000156914
ENSDART00000154714
musashi RNA-binding protein 2b
chr23_+_6795531 0.50 ENSDART00000092131
si:ch211-117c9.5
chr5_+_9408901 0.49 ENSDART00000193364

chr1_+_41690402 0.47 ENSDART00000177298
F-box protein 41
chr2_+_38924975 0.47 ENSDART00000109219
RAS (RAD and GEM)-like GTP binding 2
chr4_-_17838179 0.46 ENSDART00000146931
arginine vasopressin receptor 2, like
chr13_-_31829786 0.46 ENSDART00000138667
SERTA domain containing 4
chr25_+_35375848 0.46 ENSDART00000155721
anoctamin 3
chr6_+_11438972 0.46 ENSDART00000029314
collagen, type V, alpha 2b
chr20_-_34750363 0.45 ENSDART00000152845
zinc finger protein 395b
chr8_+_8845932 0.45 ENSDART00000112028
si:ch211-180f4.1
chr4_-_4387012 0.45 ENSDART00000191836
Danio rerio U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1-like (LOC100331497), mRNA.
chr24_-_14212521 0.44 ENSDART00000130825
XK, Kell blood group complex subunit-related family, member 9
chr4_-_25836684 0.44 ENSDART00000142491
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr17_-_45040813 0.44 ENSDART00000075514
ectonucleoside triphosphate diphosphohydrolase 5a
chr1_-_1894722 0.44 ENSDART00000165669
si:ch211-132g1.3
chr12_+_2631711 0.44 ENSDART00000114209
growth differentiation factor 10b
chr2_-_24270062 0.42 ENSDART00000192445
myosin heavy chain 7
chr7_-_29571615 0.42 ENSDART00000019140
RAR-related orphan receptor A, paralog b
chr2_+_15203322 0.42 ENSDART00000144171
ATP-binding cassette, sub-family A (ABC1), member 4b
chr3_+_56876280 0.42 ENSDART00000154197
amnion associated transmembrane protein
chr2_+_51783120 0.41 ENSDART00000177559
crystallin, gamma N1
chr20_-_6812688 0.41 ENSDART00000170934
insulin-like growth factor binding protein 1a
chr20_-_28349144 0.41 ENSDART00000179690
ENSDART00000188059
INO80 complex subunit
chr5_-_37117778 0.41 ENSDART00000149138
interleukin 13 receptor, alpha 2
chr15_-_1198886 0.40 ENSDART00000063285
latexin
chr4_+_842010 0.40 ENSDART00000067461
si:ch211-152c2.3
chr9_+_14010823 0.40 ENSDART00000143837
si:ch211-67e16.3
chr9_-_51323545 0.40 ENSDART00000139316
solute carrier family 4, sodium bicarbonate transporter, member 10b
chr7_-_16562200 0.40 ENSDART00000169093
ENSDART00000173491
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr20_-_35512932 0.40 ENSDART00000137690
adhesion G protein-coupled receptor F3b
chr7_-_28413224 0.39 ENSDART00000076502
RERG/RAS-like b
chr22_-_11626014 0.38 ENSDART00000063133
ENSDART00000160085
glucagon a
chr9_+_42095220 0.38 ENSDART00000148317
ENSDART00000134431
poly(rC) binding protein 3
chr11_-_3629201 0.38 ENSDART00000136577
ENSDART00000132121
inter-alpha-trypsin inhibitor heavy chain 3a
chr17_+_30205258 0.38 ENSDART00000076596
ENSDART00000153795
spermatogenesis associated 17
chr2_-_11662851 0.38 ENSDART00000145108
zgc:110130
chr2_+_31454562 0.37 ENSDART00000136360
si:dkey-32m20.1
chr23_-_24856025 0.37 ENSDART00000142171
synaptotagmin VIa
chr2_+_7192966 0.37 ENSDART00000142735
si:ch211-13f8.1
chr25_+_8407892 0.37 ENSDART00000153536
mucin 5.2
chr13_+_8840772 0.37 ENSDART00000059321
epithelial cell adhesion molecule
chr13_+_29352842 0.36 ENSDART00000113009
oxoglutarate dehydrogenase like
chr16_+_11652591 0.36 ENSDART00000133876
si:dkey-250k15.9
chr14_+_36886950 0.36 ENSDART00000183719
si:ch211-132p1.3
chr17_-_14726824 0.36 ENSDART00000162947
si:ch73-305o9.3
chr3_-_8873716 0.36 ENSDART00000171798
zinc finger protein 1150
chr19_-_677713 0.36 ENSDART00000025146
solute carrier family 6 (neutral amino acid transporter), member 19a, tandem duplicate 1
chr17_-_28770800 0.35 ENSDART00000156485
opsin 6, group member b
chr20_+_27020201 0.35 ENSDART00000126919
ENSDART00000016014
chromogranin A
chr24_+_3963684 0.34 ENSDART00000182959
ENSDART00000185926
ENSDART00000167043
ENSDART00000033394
phosphofructokinase, platelet a
chr15_+_7054754 0.34 ENSDART00000149800
forkhead box L2a
chr3_+_52737565 0.34 ENSDART00000108639
GEM interacting protein
chr17_-_20143946 0.33 ENSDART00000138911
actinin, alpha 2b
chr7_+_34231782 0.33 ENSDART00000173547
lactase-like a
chr8_+_14058646 0.33 ENSDART00000080852
UDP glucuronosyltransferase 5 family, polypeptide E1
chr16_+_17763848 0.33 ENSDART00000149408
ENSDART00000148878
thioesterase superfamily member 4
chr14_-_9400552 0.33 ENSDART00000129485
ENSDART00000131341
T-box 22
chr5_+_30179010 0.33 ENSDART00000134624
ADAM metallopeptidase with thrombospondin type 1 motif, 15a
chr10_+_15088534 0.32 ENSDART00000142865
si:ch211-95j8.3
chr21_-_37951819 0.32 ENSDART00000139549
si:dkey-38k9.5
chr23_-_14990865 0.32 ENSDART00000147799
ndrg family member 3b
chr24_-_32522587 0.32 ENSDART00000048968
ENSDART00000143781
zgc:56676
chr8_+_25302172 0.32 ENSDART00000046182
ENSDART00000145316
glutathione S-transferase mu tandem duplicate 3
chr8_-_13029297 0.32 ENSDART00000144305
DENN/MADD domain containing 2Da
chr22_-_20720427 0.31 ENSDART00000105532
ornithine decarboxylase antizyme 1a
chr10_-_39154594 0.31 ENSDART00000148825
solute carrier family 37 (glucose-6-phosphate transporter), member 4b
chr9_+_13999620 0.31 ENSDART00000143229
cd28-like molecule
chr21_+_11685009 0.31 ENSDART00000014668
proprotein convertase subtilisin/kexin type 1
chr12_-_34035364 0.31 ENSDART00000087065
TIMP metallopeptidase inhibitor 2a
chr18_+_8805575 0.30 ENSDART00000137098
IMP (inosine 5'-monophosphate) dehydrogenase 1a
chr6_-_52796212 0.30 ENSDART00000154133
recombination signal binding protein for immunoglobulin kappa J region-like
chr2_+_1486822 0.30 ENSDART00000132500
complement component 8, alpha polypeptide
chr1_-_45888608 0.30 ENSDART00000139219
patatin-like phospholipase domain containing 6
chr6_-_39218609 0.30 ENSDART00000133305
osteosarcoma amplified 9, endoplasmic reticulum lectin
chr3_-_11878490 0.30 ENSDART00000129961
coronin 7
chr21_+_11684830 0.29 ENSDART00000147473
proprotein convertase subtilisin/kexin type 1
chr8_-_9118958 0.29 ENSDART00000037922
solute carrier family 6 (neurotransmitter transporter), member 8
chr4_+_74255904 0.29 ENSDART00000174385
protein tyrosine phosphatase, receptor type, r
chr5_-_64823750 0.29 ENSDART00000140305
limb and CNS expressed 1
chr18_+_20468157 0.29 ENSDART00000100665
ENSDART00000147867
ENSDART00000060302
ENSDART00000180370
damage-specific DNA binding protein 2
chr7_-_67214972 0.29 ENSDART00000156861
switching B cell complex subunit SWAP70a
chr21_-_40015530 0.29 ENSDART00000084237
solute carrier family 47 (multidrug and toxin extrusion), member 2.1
chr11_-_34522249 0.29 ENSDART00000158616
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr21_-_25573064 0.29 ENSDART00000134310

chr15_+_28106498 0.29 ENSDART00000041707
unc-119 homolog a (C. elegans)
chr6_-_49873020 0.28 ENSDART00000148511
GNAS complex locus
chr16_-_11779508 0.27 ENSDART00000136329
ENSDART00000060145
ENSDART00000141101
platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit
chr21_-_14815952 0.27 ENSDART00000134278
ENSDART00000067004
phosphohistidine phosphatase 1
chr19_-_41213718 0.27 ENSDART00000077121
pyruvate dehydrogenase kinase, isozyme 4
chr11_+_25064519 0.27 ENSDART00000016181
ndrg family member 3a
chr13_-_33317323 0.27 ENSDART00000110295
ENSDART00000144848
ENSDART00000136701
transmembrane protein 234
chr6_-_40098641 0.26 ENSDART00000017402
inositol hexakisphosphate kinase 2b
chr5_-_55752169 0.26 ENSDART00000097424
potassium channel modulatory factor 1
chr9_-_15208129 0.26 ENSDART00000137043
ENSDART00000131512
par-3 family cell polarity regulator beta b
chr2_+_1487118 0.26 ENSDART00000147283
complement component 8, alpha polypeptide
chr19_+_47783137 0.26 ENSDART00000024777
ENSDART00000158979
c19h1orf109 homolog (H. sapiens)
chr25_-_5119162 0.26 ENSDART00000153961
shisa like 1b
chr13_-_32995324 0.26 ENSDART00000140542
ENSDART00000037740
potassium voltage-gated channel, subfamily F, member 1b
chr2_+_243778 0.26 ENSDART00000182262

chr4_-_16644708 0.26 ENSDART00000042307
SIN3-HDAC complex associated factor
chr18_-_14691727 0.26 ENSDART00000010129
peptide deformylase, mitochondrial
chr13_+_36770738 0.26 ENSDART00000146696
atlastin GTPase 1
chr4_+_4267451 0.26 ENSDART00000192069
anoctamin 2
chr23_+_40460333 0.26 ENSDART00000184658
SOGA family member 3b
chr14_+_29200772 0.25 ENSDART00000166608
si:dkey-34l15.2
chr14_+_31739568 0.25 ENSDART00000183507
adhesion G protein-coupled receptor G4a
chr16_-_41465542 0.25 ENSDART00000169116
ENSDART00000187446
copine IVa
chr6_-_7439490 0.25 ENSDART00000188825
FK506 binding protein 11
chr5_-_37900350 0.25 ENSDART00000084839
ENSDART00000084841
ENSDART00000133437
transmembrane protease, serine 13b
chr24_+_20927135 0.25 ENSDART00000144883
ENSDART00000131829
family with sequence similarity 162, member A
chr10_-_10018120 0.25 ENSDART00000132375
spermatid perinuclear RNA binding protein
chr1_-_28089557 0.25 ENSDART00000161024
ENSDART00000167875
small nuclear RNA activating complex, polypeptide 3
chr20_+_7084154 0.25 ENSDART00000136448
finTRIM family, member 85
chr21_+_9628854 0.25 ENSDART00000161753
ENSDART00000160711
mitogen-activated protein kinase 10
chr8_+_51050554 0.24 ENSDART00000166249
si:dkey-32e23.6
chr10_-_22127942 0.24 ENSDART00000133374
plac8 onzin related protein 2
chr21_-_37733571 0.24 ENSDART00000176214
membrane protein, palmitoylated 1
chr15_-_16070731 0.24 ENSDART00000122099
dynein, light chain, LC8-type 2a
chr2_-_17044959 0.24 ENSDART00000090260
chloride channel, voltage-sensitive 2a
chr8_+_3379815 0.24 ENSDART00000155995
zgc:136963
chr5_-_68927728 0.24 ENSDART00000132838
ankyrin 1, erythrocytic a
chr21_-_14803366 0.24 ENSDART00000190872
si:dkey-11o18.5
chr16_-_22225295 0.24 ENSDART00000163519

chr2_+_50477779 0.23 ENSDART00000122716

chr11_+_30314885 0.23 ENSDART00000187418
ENSDART00000123244
UDP glucuronosyltransferase 1 family, polypeptide B2
chr24_+_22039964 0.23 ENSDART00000081220
ankyrin repeat domain 33ba
chr16_+_21801277 0.23 ENSDART00000088407
tripartite motif containing 108
chr23_+_33907899 0.23 ENSDART00000159445
citrate synthase
chr13_-_15702672 0.23 ENSDART00000144445
ENSDART00000168950
creatine kinase, brain a
chr23_-_27701361 0.23 ENSDART00000186688
ENSDART00000183985
DnaJ (Hsp40) homolog, subfamily C, member 22
chr12_-_6880694 0.23 ENSDART00000171846
protocadherin-related 15b
chr11_+_34522554 0.22 ENSDART00000109833
zinc finger, matrin-type 3
chr8_+_20624510 0.22 ENSDART00000138604
nuclear factor I/C
chr11_+_42422638 0.22 ENSDART00000042599
ENSDART00000181175
DENN/MADD domain containing 6Aa
chr20_+_66857 0.22 ENSDART00000114999
leucine rich repeat and fibronectin type III domain containing 2b
chr19_+_29798064 0.21 ENSDART00000167803
ENSDART00000051804
MARCKS-like 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of nkx2.2a

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0019556 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.3 3.3 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.2 0.6 GO:0097623 potassium ion export(GO:0071435) potassium ion export across plasma membrane(GO:0097623)
0.2 1.0 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.2 0.5 GO:0042908 xenobiotic transport(GO:0042908)
0.2 0.6 GO:0006530 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.1 0.6 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.3 GO:0090278 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
0.1 0.3 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.9 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.5 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.1 0.4 GO:0035994 response to muscle stretch(GO:0035994)
0.1 0.3 GO:0035971 peptidyl-histidine dephosphorylation(GO:0035971)
0.1 0.3 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 0.4 GO:0042766 nucleosome mobilization(GO:0042766)
0.1 0.4 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.3 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 0.2 GO:0065001 specification of axis polarity(GO:0065001)
0.1 0.2 GO:0042730 fibrinolysis(GO:0042730)
0.1 0.2 GO:0090199 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 0.2 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.1 0.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.3 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 1.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.3 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.5 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.0 0.7 GO:0006570 tyrosine metabolic process(GO:0006570)
0.0 0.2 GO:0090299 regulation of neural crest formation(GO:0090299)
0.0 0.3 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.5 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.9 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.4 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.6 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.4 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.3 GO:1900186 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.3 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.3 GO:0055062 phosphate ion homeostasis(GO:0055062) trivalent inorganic anion homeostasis(GO:0072506)
0.0 0.6 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.3 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.5 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.0 0.5 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.3 GO:0061615 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.3 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.0 0.1 GO:0046351 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
0.0 0.1 GO:0072047 proximal/distal pattern formation involved in nephron development(GO:0072047) distal tubule morphogenesis(GO:0072156) proximal/distal pattern formation involved in pronephric nephron development(GO:0072196)
0.0 0.2 GO:0002931 response to ischemia(GO:0002931)
0.0 0.1 GO:0046125 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.2 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.7 GO:0007634 optokinetic behavior(GO:0007634)
0.0 0.3 GO:0048669 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.1 GO:0021698 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.8 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.7 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.2 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 4.4 GO:0007601 visual perception(GO:0007601)
0.0 1.5 GO:0048841 regulation of axon extension involved in axon guidance(GO:0048841)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.5 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.1 GO:0006972 hyperosmotic response(GO:0006972)
0.0 0.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.3 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 0.1 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.0 0.4 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.3 GO:0090316 positive regulation of intracellular protein transport(GO:0090316)
0.0 0.2 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.6 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.0 GO:2000378 negative regulation of gliogenesis(GO:0014014) positive regulation of DNA binding(GO:0043388) negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.0 0.1 GO:0086010 membrane depolarization(GO:0051899) membrane depolarization during action potential(GO:0086010)
0.0 0.0 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.7 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.0 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.1 GO:0034695 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.0 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.0 0.1 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.0 0.4 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.3 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.1 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 0.6 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 0.3 GO:0009411 response to UV(GO:0009411)
0.0 0.0 GO:0042543 protein N-linked glycosylation via arginine(GO:0042543)
0.0 0.1 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.4 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.0 1.7 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.2 GO:0019934 cGMP-mediated signaling(GO:0019934)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.6 GO:0005883 neurofilament(GO:0005883)
0.1 1.2 GO:0031045 dense core granule(GO:0031045)
0.1 0.7 GO:0071914 prominosome(GO:0071914)
0.1 0.2 GO:0019185 snRNA-activating protein complex(GO:0019185)
0.1 1.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.5 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.3 GO:0042583 chromaffin granule(GO:0042583)
0.1 0.9 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.8 GO:0043209 myelin sheath(GO:0043209)
0.0 0.4 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.8 GO:0032590 neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590)
0.0 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.3 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.7 GO:0005861 troponin complex(GO:0005861)
0.0 0.5 GO:0005844 polysome(GO:0005844)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.4 GO:0005882 intermediate filament(GO:0005882)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 0.1 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:1990923 PET complex(GO:1990923)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0016841 ammonia-lyase activity(GO:0016841)
0.2 0.9 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.2 0.7 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.6 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.6 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.3 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.4 GO:0031769 glucagon receptor binding(GO:0031769)
0.1 0.3 GO:0101006 protein histidine phosphatase activity(GO:0101006)
0.1 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.2 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 1.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.3 GO:0051430 mu-type opioid receptor binding(GO:0031852) dopamine receptor binding(GO:0050780) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.3 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.6 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.8 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.4 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.7 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 0.5 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.2 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.0 0.3 GO:0001032 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 3 promoter sequence-specific DNA binding(GO:0001006) RNA polymerase III regulatory region DNA binding(GO:0001016) RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 1.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.4 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 3.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 1.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.3 GO:0005113 patched binding(GO:0005113)
0.0 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.3 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.2 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.3 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.3 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.7 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.1 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 1.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0050699 WW domain binding(GO:0050699)
0.0 0.8 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.6 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.1 GO:0004133 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.0 0.5 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.1 GO:0052726 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726)
0.0 0.1 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.0 3.2 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.2 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.1 GO:0002061 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.0 3.0 GO:0015293 symporter activity(GO:0015293)
0.0 0.3 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.8 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.0 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.8 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.7 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 0.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.2 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 0.6 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.1 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.6 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 2.0 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors