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PRJEB1986: zebrafish developmental stages transcriptome

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Results for nfia

Z-value: 1.42

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Transcription factors associated with nfia

Gene Symbol Gene ID Gene Info
ENSDARG00000062420 nuclear factor I/A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nfiadr11_v1_chr22_-_16997246_169972460.571.1e-02Click!

Activity profile of nfia motif

Sorted Z-values of nfia motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_30729745 2.48 ENSDART00000103270
solute carrier family 22 (organic anion transporter), member 7a
chr6_+_13742899 2.21 ENSDART00000104722
cyclin-dependent kinase 5, regulatory subunit 2a (p39)
chr24_-_24038800 2.16 ENSDART00000080549
lysozyme
chr9_-_22182396 2.14 ENSDART00000101809
crystallin, gamma M2d6
chr3_-_55139127 2.00 ENSDART00000115324
hemoglobin, alpha embryonic 1.3
chr12_+_13256415 1.94 ENSDART00000144542
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, like
chr22_+_38767780 1.88 ENSDART00000149499
alkaline phosphatase, intestinal, tandem duplicate 1
chr5_-_41831646 1.84 ENSDART00000134326
si:dkey-65b12.6
chr16_+_31802203 1.82 ENSDART00000058739
ENSDART00000110834
wingless-type MMTV integration site family, member 4b
chr12_+_42436328 1.77 ENSDART00000167324
early B cell factor 3a
chr20_-_20533865 1.71 ENSDART00000125039
SIX homeobox 6b
chr17_-_19345521 1.70 ENSDART00000082085
goosecoid
chr17_-_19344999 1.70 ENSDART00000138315
goosecoid
chr2_-_27329214 1.68 ENSDART00000145835
thioredoxin related transmembrane protein 3a
chr10_-_26738209 1.67 ENSDART00000188590
fibroblast growth factor 13b
chr12_-_17712393 1.66 ENSDART00000143534
ENSDART00000010144
parvalbumin 2
chr25_+_20089986 1.64 ENSDART00000143441
ENSDART00000184073
troponin I4b, tandem duplicate 2
chr21_-_20939488 1.56 ENSDART00000039043
regulator of G protein signaling 7 binding protein b
chr23_-_32162810 1.56 ENSDART00000155905
nuclear receptor subfamily 4, group A, member 1
chr8_-_25980694 1.54 ENSDART00000135456
si:dkey-72l14.3
chr25_+_20081553 1.53 ENSDART00000174684
troponin I4b, tandem duplicate 1
chr21_+_22630627 1.52 ENSDART00000193092
si:dkeyp-69c1.7
chr8_+_48613040 1.51 ENSDART00000121432
natriuretic peptide A
chr23_-_4855122 1.44 ENSDART00000133701
solute carrier family 6 (neurotransmitter transporter), member 1a
chr1_+_26667872 1.44 ENSDART00000152803
ENSDART00000152144
ENSDART00000152785
ENSDART00000152393
hemogen
chr2_+_50626476 1.42 ENSDART00000018150
neuronal differentiation 6b
chr7_-_27686021 1.39 ENSDART00000079112
ENSDART00000100989
calcitonin/calcitonin-related polypeptide, alpha
chr17_-_30666037 1.37 ENSDART00000156509
ALK and LTK ligand 2b
chr3_+_34988670 1.35 ENSDART00000011319
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr16_-_55028740 1.35 ENSDART00000156368
ENSDART00000161704
zgc:114181
chr2_+_49522178 1.33 ENSDART00000056254
signal transducing adaptor family member 2a
chr15_+_19652807 1.32 ENSDART00000134321
ENSDART00000054426
lens intrinsic membrane protein 2.3
chr5_-_71705191 1.30 ENSDART00000187767
adenylate kinase 1
chr20_+_26702377 1.27 ENSDART00000077753
forkhead box C1b
chr3_+_26044969 1.27 ENSDART00000133523
HMG box domain containing 4a
chr9_+_12890161 1.23 ENSDART00000146477
si:ch211-167j6.4
chr17_+_51627209 1.23 ENSDART00000056886
zgc:113142
chr19_+_12915498 1.21 ENSDART00000132892
collagen triple helix repeat containing 1a
chr19_-_19721556 1.21 ENSDART00000165196
even-skipped homeobox 1
chr20_+_3934516 1.19 ENSDART00000165732
C-type lectin domain containing 11A
chr17_-_45040813 1.16 ENSDART00000075514
ectonucleoside triphosphate diphosphohydrolase 5a
chr22_-_23253252 1.16 ENSDART00000175556
LIM homeobox 9
chr16_-_45230084 1.13 ENSDART00000184652
si:dkey-33i11.4
chr1_+_49568335 1.12 ENSDART00000142957
collagen, type XVII, alpha 1a
chr14_-_34513103 1.12 ENSDART00000136306
zgc:194246
chr15_-_23645810 1.12 ENSDART00000168845
creatine kinase, muscle b
chr3_-_32541033 1.12 ENSDART00000151476
ENSDART00000055324
reticulocalbin 3, EF-hand calcium binding domain
chr6_-_15641686 1.11 ENSDART00000135583
melanophilin a
chr9_-_22057658 1.10 ENSDART00000101944
crystallin, gamma MX, like 1
chr12_+_42436920 1.08 ENSDART00000177303
early B cell factor 3a
chr20_+_9519391 1.05 ENSDART00000138797
RAD51 paralog B
chr18_+_15706160 1.05 ENSDART00000131524
si:ch211-264e16.1
chr11_-_44876005 1.04 ENSDART00000192006
opsin 6, group member a
chr22_+_18389271 1.03 ENSDART00000088270
YjeF N-terminal domain containing 3
chr16_+_10318893 1.02 ENSDART00000055380
tubulin, beta 5
chr23_-_11870962 1.00 ENSDART00000143481
si:dkey-178k16.1
chr15_+_29728377 1.00 ENSDART00000099958
zgc:153372
chr2_-_27900518 1.00 ENSDART00000109561
ENSDART00000077720
zgc:163121
chr23_-_22072716 0.99 ENSDART00000054362
polyhomeotic homolog 2a (Drosophila)
chr18_+_27318589 0.98 ENSDART00000037813
CD81 molecule b
chr21_+_22630297 0.97 ENSDART00000147175
si:dkeyp-69c1.7
chr10_-_36793412 0.97 ENSDART00000185966
dehydrogenase/reductase (SDR family) member 13a, tandem duplicate 2
chr7_-_17028015 0.97 ENSDART00000022441
developing brain homeobox 1a
chr13_-_29424454 0.97 ENSDART00000026765
solute carrier family 18 (vesicular acetylcholine transporter), member 3a
chr16_-_45209684 0.96 ENSDART00000184595
FXYD domain containing ion transport regulator 1 (phospholemman)
chr13_+_27951688 0.96 ENSDART00000050303
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr19_-_3381422 0.96 ENSDART00000105146
endothelin 1
chr3_+_32557615 0.96 ENSDART00000151608
paired box 10
chr15_-_34567370 0.95 ENSDART00000099793
sclerostin domain containing 1a
chr3_+_23221047 0.94 ENSDART00000009393
collagen, type I, alpha 1a
chr20_-_12642685 0.94 ENSDART00000173257
si:dkey-97l20.6
chr8_-_17997845 0.94 ENSDART00000121660
acyl-CoA thioesterase 11b
chr17_-_21793113 0.93 ENSDART00000104612
H6 family homeobox 3a
chr24_+_34113424 0.93 ENSDART00000105572
gastrulation brain homeobox 1
chr21_+_21374277 0.93 ENSDART00000079431
reticulon 2b
chr6_+_21202639 0.93 ENSDART00000083126
cell death-inducing DFFA-like effector c
chr12_+_6195191 0.92 ENSDART00000043236
ENSDART00000186420
protein kinase, cGMP-dependent, type Ib
chr22_+_28446365 0.91 ENSDART00000189359
ABI family, member 3 (NESH) binding protein b
chr16_+_23383316 0.91 ENSDART00000103220
keratinocyte associated protein 2
chr3_-_50865079 0.91 ENSDART00000164295
peripheral myelin protein 22a
chr7_-_71501970 0.91 ENSDART00000167823

chr1_+_37391141 0.90 ENSDART00000083593
ENSDART00000168647
SPARC-like 1
chr7_-_34184282 0.89 ENSDART00000183284
SMAD family member 6a
chr3_+_31621774 0.88 ENSDART00000076636
frizzled class receptor 2
chr17_+_20589553 0.88 ENSDART00000154447
si:ch73-288o11.4
chr2_-_4787566 0.87 ENSDART00000160663
ENSDART00000157808
tyrosine kinase, non-receptor, 2b
chr17_-_45552602 0.86 ENSDART00000154844
ENSDART00000034432
sushi domain containing 4
chr21_+_15824182 0.86 ENSDART00000065779
gonadotropin-releasing hormone 2
chr22_+_5106751 0.85 ENSDART00000138967
ataxia, cerebellar, Cayman type a
chr5_-_23317477 0.85 ENSDART00000090171
neuroligin 3b
chr1_-_43905252 0.84 ENSDART00000135477
ENSDART00000132089
si:dkey-22i16.3
chr11_-_31039533 0.84 ENSDART00000127355
immediate early response 2b
chr7_+_29951997 0.84 ENSDART00000173453
alpha-tropomyosin
chr19_+_41464870 0.82 ENSDART00000102778
distal-less homeobox 6a
chr3_+_32663865 0.82 ENSDART00000190240
si:dkey-16l2.16
chr20_+_19066858 0.82 ENSDART00000192086
SRY (sex determining region Y)-box 7
chr5_+_32222303 0.81 ENSDART00000051362
myosin heavy chain 4
chr20_-_44496245 0.80 ENSDART00000012229
FK506 binding protein 1b
chr19_+_35799384 0.80 ENSDART00000076023
angiopoietin 2b
chr24_+_2519761 0.80 ENSDART00000106619
neuritin 1a
chr14_+_3522334 0.80 ENSDART00000164547
farnesyltransferase, CAAX box, alpha
chr20_+_25340814 0.80 ENSDART00000063028
connective tissue growth factor a
chr5_-_32292965 0.79 ENSDART00000183522
ENSDART00000131983
myosin, heavy polypeptide 1.2, skeletal muscle
chr24_-_17039638 0.78 ENSDART00000048823
complement component 8, gamma polypeptide
chr12_+_18533198 0.78 ENSDART00000189729
meiosis specific with OB domains
chr8_-_52715911 0.78 ENSDART00000168241
tubulin, beta 2b
chr3_-_22228602 0.78 ENSDART00000017750
myosin, light chain 4, alkali; atrial, embryonic
chr21_-_25555355 0.77 ENSDART00000144228
si:dkey-17e16.9
chr9_+_38399912 0.76 ENSDART00000022246
ENSDART00000145892
BC1 (ubiquinol-cytochrome c reductase) synthesis-like
chr8_-_14121634 0.76 ENSDART00000184946
biglycan a
chr7_+_67451108 0.76 ENSDART00000163840
glycine cleavage system protein H (aminomethyl carrier), b
chr11_-_6265574 0.76 ENSDART00000181974
ENSDART00000104405
chemokine (C-C motif) ligand 25b
chr11_-_13151841 0.75 ENSDART00000161983
ELOVL fatty acid elongase 1b
chr16_-_17660594 0.75 ENSDART00000011936
coiled-coil domain containing 106a
chr3_-_50046004 0.74 ENSDART00000109544
si:ch1073-100f3.2
chr21_+_15713097 0.74 ENSDART00000015841
glutathione S-transferase theta 1b
chr19_+_9459050 0.73 ENSDART00000186419
si:ch211-288g17.3
chr9_+_45839260 0.73 ENSDART00000114814
twist2
chr5_-_41838354 0.73 ENSDART00000146793
si:dkey-65b12.6
chr17_+_16873417 0.73 ENSDART00000146276
iodothyronine deiodinase 2
chr1_+_50987535 0.73 ENSDART00000140657
malate dehydrogenase 1Aa, NAD (soluble)
chr20_-_27311675 0.72 ENSDART00000026088
ENSDART00000148361
ankyrin repeat and SOCS box containing 2a, tandem duplicate 1
chr8_+_4435894 0.72 ENSDART00000135464
ENSDART00000132540
SRR1 domain containing
chr11_-_3865472 0.72 ENSDART00000161426
GATA binding protein 2a
chr4_-_16412084 0.72 ENSDART00000188460
decorin
chr5_+_32247310 0.71 ENSDART00000182649
myosin, heavy chain a
chr10_+_43189325 0.70 ENSDART00000185584
versican b
chr16_+_29650698 0.70 ENSDART00000137153
tropomodulin 4 (muscle)
chr8_-_6877390 0.70 ENSDART00000170883
ENSDART00000005321
neurofilament, light polypeptide b
chr9_-_33107237 0.69 ENSDART00000013918
calsequestrin 2
chr11_-_7261717 0.69 ENSDART00000128959
zgc:113223
chr4_+_19535946 0.68 ENSDART00000192342
ENSDART00000183740
ENSDART00000180812
ENSDART00000180017
leucine rich repeat containing 4.1
chr17_+_27803608 0.68 ENSDART00000164943
QKI, KH domain containing, RNA binding a
chr2_+_26237322 0.68 ENSDART00000030520
paralemmin 1b
chr6_-_13408680 0.68 ENSDART00000151566
formin-like 2b
chr14_+_5861435 0.67 ENSDART00000041279
ENSDART00000147341
tubulin, beta 4B class IVb
chr12_+_34732262 0.67 ENSDART00000169634
si:dkey-21c1.8
chr21_+_11503212 0.66 ENSDART00000146701
si:dkey-184p9.7
chr12_-_8958353 0.66 ENSDART00000041728
cytochrome P450, family 26, subfamily A, polypeptide 1
chr1_-_22861348 0.66 ENSDART00000139412
si:dkey-92j12.6
chr21_-_22730832 0.66 ENSDART00000101797
F-box protein 40, tandem duplicate 1
chr7_-_31940590 0.65 ENSDART00000131009
brain-derived neurotrophic factor
chr6_-_41138854 0.65 ENSDART00000128723
ENSDART00000151055
ENSDART00000132484
solute carrier family 6 member 22, tandem duplicate 1
chr13_+_36633355 0.65 ENSDART00000135612
si:ch211-67f24.7
chr1_+_51475094 0.65 ENSDART00000146352
Meis homeobox 1 a
chr3_-_36612877 0.64 ENSDART00000167164
si:dkeyp-72e1.7
chr10_-_24689725 0.64 ENSDART00000079566
si:ch211-287a12.9
chr5_-_12713920 0.64 ENSDART00000099749
si:dkey-98f17.3
chr5_-_51830997 0.64 ENSDART00000163616
homer scaffolding protein 1b
chr7_-_16558665 0.64 ENSDART00000169399
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr13_-_17723417 0.64 ENSDART00000183834
voltage-dependent anion channel 2
chr9_-_15362556 0.64 ENSDART00000191233
fibronectin 1a
chr1_-_16394814 0.63 ENSDART00000013024
fibroblast growth factor 20a
chr5_-_37103487 0.63 ENSDART00000149211
interleukin 13 receptor, alpha 2
chr13_+_30804367 0.63 ENSDART00000053946
chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)
chr25_+_22587306 0.62 ENSDART00000067479
stimulated by retinoic acid 6
chr9_-_21976670 0.62 ENSDART00000104322
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr4_-_16341801 0.62 ENSDART00000140190
keratocan
chr18_-_20636549 0.61 ENSDART00000060259
wingless-type MMTV integration site family member 2
chr19_+_10831362 0.60 ENSDART00000053325
translocase of outer mitochondrial membrane 40 homolog, like
chr6_-_10809546 0.60 ENSDART00000151661
WAS/WASL interacting protein family, member 1b
chr7_+_18364176 0.60 ENSDART00000171606
ENSDART00000186368
CD248 molecule, endosialin a
chr4_+_22480169 0.59 ENSDART00000146272
ENSDART00000066904
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr2_-_14987282 0.59 ENSDART00000143057
holocytochrome c synthase a, tandem duplicate 2
chr1_-_23308225 0.59 ENSDART00000137567
ENSDART00000008201
small integral membrane protein 14
chr1_+_10305611 0.59 ENSDART00000043881
zgc:77880
chr6_+_9870192 0.59 ENSDART00000150894
si:ch211-222n4.6
chr4_+_37406676 0.59 ENSDART00000130981
si:ch73-134f24.1
chr13_-_9119867 0.59 ENSDART00000137255
si:dkey-112g5.15
chr8_-_10961991 0.59 ENSDART00000139603
tripartite motif containing 33
chr25_+_30298377 0.59 ENSDART00000153622
chromosome 11 open reading frame 96
chr3_-_6417328 0.59 ENSDART00000160979
Jupiter microtubule associated homolog 1b
chr3_+_32125452 0.58 ENSDART00000110396
zgc:194125
chr10_-_26273629 0.58 ENSDART00000147790
dachsous cadherin-related 1b
chr15_-_766015 0.57 ENSDART00000190648
si:dkey-7i4.15
chr13_+_22964868 0.57 ENSDART00000142129
tachykinin receptor 2
chr2_+_15069011 0.57 ENSDART00000145893
calponin 3, acidic b
chr17_+_33453689 0.57 ENSDART00000156894
Ras and Rab interactor 3
chr17_-_14700889 0.57 ENSDART00000179975
protein tyrosine phosphatase type IVA, member 2a
chr17_-_30839338 0.57 ENSDART00000139707
growth differentiation factor 7
chr2_-_6482240 0.56 ENSDART00000132623
regulator of G protein signaling 13
chr6_-_6993046 0.56 ENSDART00000053304
si:ch211-114n24.6
chr1_+_16463079 0.56 ENSDART00000078675
vacuolar protein sorting 37A
chr10_+_21576909 0.56 ENSDART00000168604
ENSDART00000166533
protocadherin 1 alpha 3
chr1_+_40801696 0.55 ENSDART00000147497
carboxypeptidase Z
chr25_-_13201458 0.55 ENSDART00000192451
si:ch211-194m7.4
chr25_-_19443421 0.55 ENSDART00000067362
cocaine- and amphetamine-regulated transcript 2
chr6_-_52566574 0.55 ENSDART00000098421
ubiquinol-cytochrome c reductase complex assembly factor 1
chr23_-_21515182 0.55 ENSDART00000142000
ring finger protein 207b
chr9_+_42607138 0.54 ENSDART00000138133
ENSDART00000002027
GULP, engulfment adaptor PTB domain containing 1a
chr13_+_27316934 0.54 ENSDART00000164533
eukaryotic translation elongation factor 1 alpha 1a
chr22_+_16308806 0.54 ENSDART00000162685
leucine rich repeat containing 39
chr1_+_23398405 0.54 ENSDART00000102646
ras homolog family member H
chr2_-_15040345 0.54 ENSDART00000109657
si:dkey-10f21.4
chr13_-_9024004 0.53 ENSDART00000169564
si:dkey-112g5.11
chr3_+_45401472 0.53 ENSDART00000156693
BAI1-associated protein 3
chr9_+_21151138 0.53 ENSDART00000133903
hydroxyacid oxidase 2 (long chain)
chr14_+_36886950 0.53 ENSDART00000183719
si:ch211-132p1.3
chr8_-_23884301 0.52 ENSDART00000185509
ENSDART00000147202
LHFPL tetraspan subfamily member 5b
chr4_+_2059692 0.52 ENSDART00000067427
YEATS domain containing 4

Network of associatons between targets according to the STRING database.

First level regulatory network of nfia

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:1905072 cardiac jelly development(GO:1905072)
0.5 1.4 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
0.4 1.7 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.4 1.2 GO:0097376 interneuron axon guidance(GO:0097376) spinal cord interneuron axon guidance(GO:0097377) dorsal spinal cord interneuron axon guidance(GO:0097378)
0.3 1.3 GO:0018343 protein farnesylation(GO:0018343)
0.3 1.0 GO:0042908 xenobiotic transport(GO:0042908)
0.3 1.3 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583)
0.3 0.9 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.3 0.9 GO:0042543 protein N-linked glycosylation via arginine(GO:0042543)
0.3 0.9 GO:2000257 regulation of protein activation cascade(GO:2000257)
0.3 0.9 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.3 1.1 GO:0051876 pigment granule dispersal(GO:0051876)
0.3 1.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.3 1.0 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.2 0.7 GO:0061614 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.2 0.9 GO:0035630 bone mineralization involved in bone maturation(GO:0035630)
0.2 1.4 GO:0070378 ERK5 cascade(GO:0070375) regulation of ERK5 cascade(GO:0070376) positive regulation of ERK5 cascade(GO:0070378)
0.2 1.3 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.2 3.4 GO:0010717 regulation of epithelial to mesenchymal transition(GO:0010717)
0.2 0.6 GO:1903673 mitotic cytokinetic process(GO:1902410) mitotic cleavage furrow formation(GO:1903673)
0.2 1.0 GO:0060584 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.2 0.8 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.2 0.5 GO:0060571 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.2 0.5 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.2 0.9 GO:0048664 neuron fate determination(GO:0048664)
0.2 1.2 GO:0006172 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.2 0.7 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.2 1.6 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.2 0.5 GO:0033335 anal fin development(GO:0033335)
0.2 1.7 GO:0003160 endocardium morphogenesis(GO:0003160)
0.2 0.6 GO:0035994 response to muscle stretch(GO:0035994)
0.2 0.8 GO:0072574 hepatocyte proliferation(GO:0072574) epithelial cell proliferation involved in liver morphogenesis(GO:0072575)
0.2 0.9 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.1 0.7 GO:0071422 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.1 0.7 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.1 0.7 GO:0016103 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.1 2.7 GO:0015671 oxygen transport(GO:0015671)
0.1 0.6 GO:0060956 cardiac endothelial cell differentiation(GO:0003348) endocardial cell differentiation(GO:0060956)
0.1 0.9 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.6 GO:0071938 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.1 0.4 GO:0046099 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine biosynthetic process(GO:0046099)
0.1 1.2 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.1 0.5 GO:0021742 abducens nucleus development(GO:0021742)
0.1 1.7 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.6 GO:0018063 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.1 0.5 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.1 1.2 GO:0072506 phosphate ion homeostasis(GO:0055062) trivalent inorganic anion homeostasis(GO:0072506)
0.1 0.9 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 1.0 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.5 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.1 0.7 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.1 0.3 GO:0044878 abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878)
0.1 0.8 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 1.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.4 GO:0010226 response to lithium ion(GO:0010226)
0.1 0.3 GO:0036315 response to sterol(GO:0036314) cellular response to sterol(GO:0036315) SREBP-SCAP complex retention in endoplasmic reticulum(GO:0036316) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.6 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.3 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.1 0.4 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.1 0.2 GO:0071548 response to dexamethasone(GO:0071548)
0.1 1.1 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.1 0.6 GO:0048569 post-embryonic organ development(GO:0048569)
0.1 0.5 GO:0090342 regulation of cell aging(GO:0090342)
0.1 0.4 GO:0090199 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 0.2 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.6 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.9 GO:0032095 regulation of response to food(GO:0032095)
0.1 1.4 GO:0007130 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.1 0.7 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.9 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.1 0.9 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 3.8 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.2 GO:0070314 G1 to G0 transition(GO:0070314)
0.1 0.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 0.2 GO:0021985 neurohypophysis development(GO:0021985)
0.1 0.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.2 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.1 0.4 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 0.2 GO:0018315 establishment of synaptic specificity at neuromuscular junction(GO:0007529) molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 0.4 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.3 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 1.2 GO:0042574 retinal metabolic process(GO:0042574)
0.1 0.5 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.1 0.4 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.1 0.2 GO:0014814 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.1 0.3 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.1 0.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.5 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 0.3 GO:0090527 actin filament reorganization(GO:0090527)
0.1 1.8 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.1 0.6 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.1 0.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 1.0 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 0.2 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 0.3 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.7 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 1.1 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.2 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 0.4 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 1.8 GO:0050654 chondroitin sulfate proteoglycan metabolic process(GO:0050654)
0.1 0.2 GO:0014909 smooth muscle cell migration(GO:0014909)
0.1 0.9 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.8 GO:0035141 medial fin morphogenesis(GO:0035141)
0.0 1.7 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 1.4 GO:0019835 cytolysis(GO:0019835)
0.0 0.2 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.1 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.2 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.3 GO:0010460 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.0 0.4 GO:0061056 sclerotome development(GO:0061056)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.4 GO:0007140 male meiosis(GO:0007140)
0.0 0.2 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 0.3 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.2 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 0.3 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.3 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.4 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.3 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.1 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.7 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.8 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.5 GO:0031280 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclic nucleotide metabolic process(GO:0030800) negative regulation of cyclic nucleotide biosynthetic process(GO:0030803) negative regulation of nucleotide biosynthetic process(GO:0030809) negative regulation of cAMP metabolic process(GO:0030815) negative regulation of cAMP biosynthetic process(GO:0030818) negative regulation of cyclase activity(GO:0031280) negative regulation of nucleotide metabolic process(GO:0045980) negative regulation of lyase activity(GO:0051350) negative regulation of purine nucleotide biosynthetic process(GO:1900372) negative regulation of purine nucleotide metabolic process(GO:1900543)
0.0 0.2 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.3 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.3 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.0 3.8 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.2 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 1.8 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.3 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 1.2 GO:0032456 endocytic recycling(GO:0032456)
0.0 1.4 GO:1901214 regulation of neuron death(GO:1901214)
0.0 0.8 GO:0060840 artery development(GO:0060840)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.0 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 1.0 GO:0021515 cell differentiation in spinal cord(GO:0021515)
0.0 0.3 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.3 GO:0050909 sensory perception of taste(GO:0050909)
0.0 1.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 1.1 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 1.9 GO:0031101 fin regeneration(GO:0031101)
0.0 0.3 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.2 GO:0022602 ovarian follicle development(GO:0001541) ovulation cycle process(GO:0022602) ovulation cycle(GO:0042698)
0.0 0.5 GO:1902622 regulation of neutrophil migration(GO:1902622)
0.0 0.1 GO:0034695 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.0 2.0 GO:0001503 ossification(GO:0001503)
0.0 0.2 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 1.0 GO:0007602 phototransduction(GO:0007602)
0.0 0.5 GO:0071875 adrenergic receptor signaling pathway(GO:0071875)
0.0 0.1 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.0 0.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.1 GO:0002820 negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823) regulation of T-helper 17 type immune response(GO:2000316) negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320) regulation of T-helper 17 cell lineage commitment(GO:2000328) negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 1.6 GO:0048469 cell maturation(GO:0048469)
0.0 0.1 GO:0019427 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.0 0.8 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.3 GO:0036065 fucosylation(GO:0036065)
0.0 0.1 GO:0018158 protein oxidation(GO:0018158)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.4 GO:0032355 response to estradiol(GO:0032355)
0.0 1.0 GO:0042493 response to drug(GO:0042493)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.2 GO:1901534 positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.3 GO:0071482 cellular response to light stimulus(GO:0071482)
0.0 0.4 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.4 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.5 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.8 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.5 GO:0060402 cytosolic calcium ion transport(GO:0060401) calcium ion transport into cytosol(GO:0060402)
0.0 0.3 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.1 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.6 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.3 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.0 0.4 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.2 GO:1900107 regulation of nodal signaling pathway(GO:1900107)
0.0 0.2 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.3 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 0.8 GO:0036293 response to hypoxia(GO:0001666) response to decreased oxygen levels(GO:0036293)
0.0 0.6 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.8 GO:0006936 muscle contraction(GO:0006936)
0.0 0.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 2.2 GO:0055074 calcium ion homeostasis(GO:0055074)
0.0 0.2 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.3 1.3 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.3 0.8 GO:0005960 glycine cleavage complex(GO:0005960)
0.2 2.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 1.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.2 1.3 GO:0030428 cell septum(GO:0030428)
0.1 0.7 GO:0005883 neurofilament(GO:0005883)
0.1 1.0 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.7 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.4 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.9 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 3.8 GO:0005861 troponin complex(GO:0005861)
0.1 1.4 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.4 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 0.6 GO:0046930 pore complex(GO:0046930)
0.1 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.3 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 1.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.2 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.1 0.4 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.7 GO:0042583 chromaffin granule(GO:0042583)
0.1 0.5 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 0.4 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 0.4 GO:0014704 intercalated disc(GO:0014704)
0.1 0.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 1.0 GO:0000813 ESCRT I complex(GO:0000813)
0.1 3.7 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.2 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.1 1.4 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.7 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.8 GO:0031430 M band(GO:0031430)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.1 GO:0043073 germ cell nucleus(GO:0043073)
0.0 0.4 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.3 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 1.0 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 2.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 1.3 GO:0030426 growth cone(GO:0030426)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.0 0.9 GO:0030496 midbody(GO:0030496)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126) COPI-coated vesicle membrane(GO:0030663)
0.0 0.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.3 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 17.3 GO:0005615 extracellular space(GO:0005615)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.8 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0016234 inclusion body(GO:0016234)
0.0 1.5 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.0 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 3.6 GO:0009986 cell surface(GO:0009986)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:0003796 lysozyme activity(GO:0003796)
0.5 1.4 GO:0031716 calcitonin receptor binding(GO:0031716)
0.3 1.3 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.3 0.9 GO:0030792 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.3 0.9 GO:0005183 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.3 1.0 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.2 1.7 GO:0016972 thiol oxidase activity(GO:0016972)
0.2 1.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2 1.9 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.2 1.4 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.2 2.7 GO:0031720 haptoglobin binding(GO:0031720)
0.2 0.7 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.2 0.6 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 1.0 GO:0031708 endothelin B receptor binding(GO:0031708)
0.2 2.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2 0.5 GO:0045545 syndecan binding(GO:0045545)
0.2 2.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2 1.3 GO:0004100 chitin synthase activity(GO:0004100)
0.2 0.9 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 1.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.7 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.1 0.7 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 1.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.4 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
0.1 0.6 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 0.6 GO:0015288 porin activity(GO:0015288)
0.1 0.4 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.1 1.0 GO:0036122 BMP binding(GO:0036122)
0.1 0.6 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.1 1.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 1.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.1 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 0.4 GO:0005461 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.1 1.3 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 0.3 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 1.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.6 GO:0034632 retinol transporter activity(GO:0034632)
0.1 0.5 GO:0004966 galanin receptor activity(GO:0004966)
0.1 1.1 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 0.9 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.2 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 0.6 GO:0043394 glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)
0.1 0.9 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.1 0.3 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.4 GO:0070325 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
0.1 0.2 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 1.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 5.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.3 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.1 1.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.3 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.1 2.3 GO:0005109 frizzled binding(GO:0005109)
0.1 2.1 GO:0005518 collagen binding(GO:0005518)
0.1 0.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.1 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 0.2 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.1 0.5 GO:0030546 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.1 0.7 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 0.2 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.0 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 2.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.0 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.4 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.9 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0070888 E-box binding(GO:0070888)
0.0 0.6 GO:0005537 mannose binding(GO:0005537)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.6 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.3 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.9 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.5 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.4 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.3 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.5 GO:0031386 protein tag(GO:0031386)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.4 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.4 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.5 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0008459 chondroitin 6-sulfotransferase activity(GO:0008459)
0.0 0.7 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.7 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.4 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.1 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.5 GO:0010181 FMN binding(GO:0010181)
0.0 0.3 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.5 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.4 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.0 GO:0017022 myosin binding(GO:0017022)
0.0 0.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.8 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.0 0.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 1.0 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 2.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.8 GO:0005178 integrin binding(GO:0005178)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.9 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 1.0 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.3 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.8 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 1.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:2001069 glycogen binding(GO:2001069)
0.0 0.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 7.0 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 1.3 GO:0008083 growth factor activity(GO:0008083)
0.0 0.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 1.1 GO:0005179 hormone activity(GO:0005179)
0.0 0.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.7 GO:0031625 ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.0 0.3 GO:0098631 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 0.6 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 1.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 2.7 PID AP1 PATHWAY AP-1 transcription factor network
0.1 3.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 0.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 2.0 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 0.9 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 1.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.7 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 1.0 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 0.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 0.5 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 1.9 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 0.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.0 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 1.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.1 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions