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PRJEB1986: zebrafish developmental stages transcriptome

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Results for nfatc2a

Z-value: 1.18

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Transcription factors associated with nfatc2a

Gene Symbol Gene ID Gene Info
ENSDARG00000100927 nuclear factor of activated T cells 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nfatc2adr11_v1_chr23_+_39089574_390895740.589.9e-03Click!

Activity profile of nfatc2a motif

Sorted Z-values of nfatc2a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_19616799 1.58 ENSDART00000143077
F-box protein 10
chr13_+_32740509 1.34 ENSDART00000076423
ENSDART00000160138
sine oculis binding protein homolog (Drosophila) a
chr13_-_298454 1.34 ENSDART00000135782
chitin synthase 1
chr6_-_48094342 1.29 ENSDART00000137458
solute carrier family 2 (facilitated glucose transporter), member 1b
chr22_-_3914162 1.26 ENSDART00000187174
ENSDART00000190612
ENSDART00000187928
ENSDART00000057224
ENSDART00000184758
major histocompatibility complex class I UMA
chr8_+_22931427 1.26 ENSDART00000063096
synaptophysin a
chr17_+_33340675 1.18 ENSDART00000184396
ENSDART00000077553
xanthine dehydrogenase
chr20_+_46040666 1.17 ENSDART00000060744
si:dkey-7c18.24
chr17_-_45370200 1.17 ENSDART00000186208
zinc finger protein 106a
chr14_+_40874608 1.14 ENSDART00000168448
si:ch211-106m9.1
chr5_-_26118855 1.14 ENSDART00000009028
elastase 3 like
chr20_-_805245 1.13 ENSDART00000131825
interphotoreceptor matrix proteoglycan 1a
chr3_+_12593558 1.11 ENSDART00000186891
ENSDART00000159252
ATP-binding cassette, sub-family A (ABC1), member 3b
chr23_+_40460333 1.07 ENSDART00000184658
SOGA family member 3b
chr16_+_45746549 1.03 ENSDART00000190403
progestin and adipoQ receptor family member VI
chr17_-_51938663 1.03 ENSDART00000179784
ergosterol biosynthesis 28 homolog
chr3_+_17744339 1.01 ENSDART00000132622
zinc finger protein 385C
chr8_+_53423408 0.95 ENSDART00000164792
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr3_+_9332984 0.94 ENSDART00000185184
ENSDART00000183535

chr21_-_21089781 0.91 ENSDART00000144361
ankyrin 1, erythrocytic b
chr8_-_46572298 0.90 ENSDART00000030470
sulfotransferase family 1, cytosolic sulfotransferase 3
chr10_-_7666810 0.88 ENSDART00000191479
prenylcysteine oxidase 1
chr17_-_6730247 0.88 ENSDART00000031091
visinin-like 1b
chr22_+_3914318 0.88 ENSDART00000188774
ENSDART00000082034
Danio rerio major histocompatibility complex class I ULA (mhc1ula), mRNA.
chr3_+_14463941 0.87 ENSDART00000170927
calponin 1, basic, smooth muscle, b
chr16_+_45739193 0.87 ENSDART00000184852
ENSDART00000156851
ENSDART00000154704
progestin and adipoQ receptor family member VI
chr7_+_60551133 0.86 ENSDART00000148038
leucine rich repeat and fibronectin type III domain containing 4b
chr17_+_27456804 0.86 ENSDART00000017756
ENSDART00000181461
ENSDART00000180178
cathepsin L.1
chr23_-_7826849 0.86 ENSDART00000157612
myelin transcription factor 1b
chr20_-_25518488 0.85 ENSDART00000186993
cytochrome P450, family 2, subfamily N, polypeptide 13
chr1_-_59415948 0.82 ENSDART00000168614
si:ch211-188p14.4
chr9_+_42063906 0.81 ENSDART00000048893
poly(rC) binding protein 3
chr25_-_5740334 0.80 ENSDART00000169622
ENSDART00000168720

chr25_-_21085661 0.80 ENSDART00000099355
proline rich 5a (renal)
chr20_+_31985461 0.80 ENSDART00000191961

chr9_-_23994225 0.78 ENSDART00000140346
collagen, type VI, alpha 3
chr5_+_63668735 0.78 ENSDART00000134261
ENSDART00000097330
dynamin 1b
chr8_-_4327473 0.77 ENSDART00000134378
cut-like homeobox 2b
chr12_+_33403694 0.77 ENSDART00000124083
fatty acid synthase
chr2_-_11082914 0.77 ENSDART00000081026
family with sequence similarity 151, member A
chr16_+_45930962 0.76 ENSDART00000124689
ENSDART00000041811
OTU deubiquitinase 7B
chr2_-_37353098 0.76 ENSDART00000056522
SKI-like proto-oncogene a
chr23_+_16948049 0.76 ENSDART00000139449
si:dkey-147f3.4
chr6_-_52428826 0.74 ENSDART00000047399
matrix metallopeptidase 24
chr5_-_37157510 0.74 ENSDART00000166710
leucine-rich repeats and calponin homology (CH) domain containing 2
chr8_+_26859639 0.74 ENSDART00000133440
PR domain containing 2, with ZNF domain a
chr2_-_33993533 0.74 ENSDART00000140910
ENSDART00000077304
patched 2
chr5_+_55626693 0.73 ENSDART00000168908
ENSDART00000161412
neurotrophic tyrosine kinase, receptor, type 2b
chr23_-_7797207 0.73 ENSDART00000181611
myelin transcription factor 1b
chr1_+_54626491 0.73 ENSDART00000136063
si:ch211-202h22.9
chr4_-_1720648 0.73 ENSDART00000103484
growth arrest-specific 2 like 3
chr9_-_42989297 0.73 ENSDART00000126871
titin, tandem duplicate 2
chr3_-_61181018 0.73 ENSDART00000187970
parvalbumin 4
chr2_+_33541928 0.73 ENSDART00000162852

chr8_-_7502166 0.73 ENSDART00000176938
cyclin-dependent kinase 20
chr23_+_17220986 0.72 ENSDART00000054761
nucleolar protein 4-like b
chr5_-_40190949 0.71 ENSDART00000175588
WD repeat and FYVE domain containing 3
chr9_-_49464993 0.71 ENSDART00000181471
xin actin binding repeat containing 2b
chr10_-_2682198 0.71 ENSDART00000183727
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr15_+_11693624 0.70 ENSDART00000193630
ENSDART00000161930
striatin, calmodulin binding protein 4
chr9_-_35069645 0.70 ENSDART00000122679
ENSDART00000077908
ENSDART00000077894
ENSDART00000125536
amyloid beta (A4) precursor protein b
chr17_-_17130942 0.70 ENSDART00000064241
neurexin 3a
chr16_+_43152727 0.70 ENSDART00000125590
ENSDART00000154493
ADAM metallopeptidase domain 22
chr14_-_2036604 0.70 ENSDART00000192446

chr20_-_43771871 0.70 ENSDART00000153304
matrilin 3a
chr23_-_25976656 0.69 ENSDART00000019519
adenosine deaminase
chr22_+_1911269 0.69 ENSDART00000164158
ENSDART00000168205
zinc finger protein 1156
chr1_+_38858399 0.69 ENSDART00000165454

chr23_+_19790962 0.69 ENSDART00000142228
filamin A, alpha (actin binding protein 280)
chr2_+_38804223 0.69 ENSDART00000147939
capping protein regulator and myosin 1 linker 3
chr12_-_7710563 0.69 ENSDART00000187382

chr3_-_18274691 0.69 ENSDART00000161140

chr2_+_24199276 0.69 ENSDART00000140575
microtubule associated protein 4 like
chr19_+_19241372 0.69 ENSDART00000184392
ENSDART00000165008
protein tyrosine phosphatase, non-receptor type 23, b
chr5_-_3209345 0.68 ENSDART00000171477

chr17_-_33289304 0.67 ENSDART00000135118
ENSDART00000040346
EFR3 homolog Ba (S. cerevisiae)
chr16_-_16212615 0.67 ENSDART00000059905
uridine phosphorylase 1
chr18_-_46063773 0.67 ENSDART00000078561
si:ch73-262h23.4
chr5_-_69041102 0.67 ENSDART00000161561
ankyrin 1, erythrocytic a
chr22_-_6562618 0.67 ENSDART00000106100
zgc:171490
chr9_-_27442339 0.66 ENSDART00000138602
syntaxin binding protein 5-like
chr1_+_45217425 0.66 ENSDART00000179983
ENSDART00000074683
si:ch211-239f4.1
chr3_-_33901483 0.65 ENSDART00000144774
ENSDART00000138765
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a
chr5_+_36768674 0.65 ENSDART00000146854
MAP/microtubule affinity-regulating kinase 4a
chr7_+_20966434 0.65 ENSDART00000185570
ephrin-B3b
chr11_+_29975830 0.65 ENSDART00000148929
si:ch73-226l13.2
chr21_+_6291027 0.65 ENSDART00000180467
ENSDART00000184952
ENSDART00000184006
formin binding protein 1b
chr11_+_41540862 0.65 ENSDART00000173210
potassium voltage-gated channel, shaker-related subfamily, beta member 2 a
chr19_-_677713 0.65 ENSDART00000025146
solute carrier family 6 (neutral amino acid transporter), member 19a, tandem duplicate 1
chr9_-_19092322 0.65 ENSDART00000131957
cytokine receptor family member b2
chr12_-_4651988 0.65 ENSDART00000182836
si:ch211-255p10.4
chr3_+_19621034 0.64 ENSDART00000025358
integrin beta 3a
chr10_+_21701568 0.64 ENSDART00000090748
protocadherin 1 gamma 9
chr12_+_10115964 0.64 ENSDART00000152369
si:dkeyp-118b1.2
chr9_-_12575776 0.64 ENSDART00000128931
ENSDART00000182695
insulin-like growth factor 2 mRNA binding protein 2a
chr17_+_890988 0.64 ENSDART00000186843

chr10_+_17026870 0.63 ENSDART00000184529
ENSDART00000157480

chr20_-_18731268 0.63 ENSDART00000183893
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr3_+_24482999 0.63 ENSDART00000059179
neuronal pentraxin receptor a
chr1_+_44442140 0.63 ENSDART00000190592
crystallin, beta B1, like 2
chr20_-_791788 0.62 ENSDART00000134128
interphotoreceptor matrix proteoglycan 1a
chr8_+_17143501 0.62 ENSDART00000061758
mesoderm induction early response 1, family member 3 b
chr9_+_17423941 0.62 ENSDART00000112884
ENSDART00000155233
kelch repeat and BTB (POZ) domain containing 7
chr12_+_18234557 0.62 ENSDART00000130741
family with sequence similarity 20, member Cb
chr12_-_17897134 0.61 ENSDART00000066407
neuronal pentraxin IIb
chr4_-_15420452 0.61 ENSDART00000016230
plexin A4
chr6_-_49078702 0.61 ENSDART00000135185
solute carrier family 5 (iodide transporter), member 8-like
chr9_+_7909490 0.61 ENSDART00000133063
ENSDART00000109288
myosin XVI
chr23_-_36003441 0.61 ENSDART00000164699
calcium binding and coiled-coil domain 1a
chr3_+_12732382 0.61 ENSDART00000158403
cytochrome P450, family 2, subfamily k, polypeptide 19
chr4_+_61995745 0.61 ENSDART00000171539

chr25_-_17395315 0.60 ENSDART00000064596
cytochrome P450, family 2, subfamily X, polypeptide 8
chr23_+_1181248 0.60 ENSDART00000170942
utrophin
chr22_-_17953529 0.60 ENSDART00000135716
neurocan b
chr22_+_17536989 0.60 ENSDART00000149531
heterogeneous nuclear ribonucleoprotein M
chr15_-_10455438 0.60 ENSDART00000158958
ENSDART00000192971
ENSDART00000162133
ENSDART00000185071
ENSDART00000192444
ENSDART00000165668
ENSDART00000175825
teneurin transmembrane protein 4
chr10_-_3258073 0.60 ENSDART00000113162
phosphatidylinositol 4-kinase, catalytic, alpha a
chr17_+_28683574 0.59 ENSDART00000152000
HECT domain containing 1
chr15_+_32710300 0.59 ENSDART00000167857
periostin, osteoblast specific factor b
chr4_+_74554605 0.59 ENSDART00000009653
potassium voltage-gated channel, shaker-related subfamily, member 1b
chr14_-_14604527 0.59 ENSDART00000190378
RAB9B, member RAS oncogene family
chr7_+_18176162 0.59 ENSDART00000109171
Ras converting CAAX endopeptidase 1a
chr3_-_5067585 0.59 ENSDART00000169609
thyrotrophic embryonic factor b
chr21_-_5958387 0.59 ENSDART00000130521
si:ch73-209e20.5
chr23_+_4288964 0.59 ENSDART00000138408
l(3)mbt-like 1 (Drosophila)
chr11_+_6819050 0.59 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr16_+_48714048 0.59 ENSDART00000148709
ENSDART00000150121
bromodomain containing 2b
chr2_+_24199073 0.59 ENSDART00000144110
microtubule associated protein 4 like
chr1_-_52201266 0.59 ENSDART00000143805
ENSDART00000023757
RAB3D, member RAS oncogene family, a
chr16_+_30117798 0.58 ENSDART00000135723
ENSDART00000000198
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E
chr22_-_294700 0.58 ENSDART00000189179

chr6_+_11850359 0.58 ENSDART00000109552
ENSDART00000188139
ENSDART00000181499
ENSDART00000178269
bromodomain adjacent to zinc finger domain, 2Ba
chr1_+_11977426 0.58 ENSDART00000103399
tetraspanin 5b
chr23_+_21566828 0.58 ENSDART00000134741
ENSDART00000111966
Rho guanine nucleotide exchange factor (GEF) 10-like b
chr12_-_3453589 0.58 ENSDART00000175918

chr20_+_41664350 0.58 ENSDART00000186247
family with sequence similarity 184, member A
chr11_-_24015845 0.57 ENSDART00000191783
chitinase, acidic.3
chr3_+_39540014 0.57 ENSDART00000074848
zgc:165423
chr22_+_28320792 0.57 ENSDART00000160562
ENSDART00000164138
interphotoreceptor matrix proteoglycan 2b
interphotoreceptor matrix proteoglycan 2b
chr4_+_74551606 0.57 ENSDART00000174339
potassium voltage-gated channel, shaker-related subfamily, member 1b
chr9_-_55790458 0.57 ENSDART00000161247
sosondowah ankyrin repeat domain family Ca
chr3_+_24459709 0.57 ENSDART00000180976
chromobox homolog 6b
chr4_+_331351 0.57 ENSDART00000132625
tubby like protein 4a
chr25_-_4235037 0.57 ENSDART00000093003
synaptotagmin VIIa
chr25_+_10811551 0.57 ENSDART00000167730
alanyl (membrane) aminopeptidase b
chr10_-_44411032 0.57 ENSDART00000111509

chr1_-_5455498 0.57 ENSDART00000040368
ENSDART00000114035
motor neuron and pancreas homeobox 2b
chr25_+_31122806 0.56 ENSDART00000067039
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8a
chr2_-_57143477 0.56 ENSDART00000167441
armadillo repeat containing 6
chr20_-_16548912 0.56 ENSDART00000137601
checkpoint suppressor 1
chr20_-_53624645 0.56 ENSDART00000083427
ENSDART00000152920
solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29
chr6_+_2195625 0.56 ENSDART00000155659
activin A receptor type 1Bb
chr11_-_38083397 0.55 ENSDART00000086516
ENSDART00000184033
kelch domain containing 8A
chr7_-_57933736 0.55 ENSDART00000142580
ankyrin 2b, neuronal
chr1_+_52632856 0.55 ENSDART00000011725
solute carrier family 44 (choline transporter), member 1a
chr5_-_41049690 0.55 ENSDART00000174936
ENSDART00000135030
PDZ domain containing 2
chr21_+_40417152 0.55 ENSDART00000171244
slingshot protein phosphatase 2b
chr20_-_25533739 0.55 ENSDART00000063064
cytochrome P450, family 2, subfamily AD, polypeptide 6
chr21_+_31150773 0.55 ENSDART00000126205
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr6_+_53349966 0.55 ENSDART00000167079
si:ch211-161c3.5
chr10_+_21677058 0.55 ENSDART00000171499
ENSDART00000157516
protocadherin 1 gamma b 2
chr23_+_37482727 0.55 ENSDART00000162737
agmatine ureohydrolase (agmatinase)
chr10_-_11385155 0.55 ENSDART00000064214
placenta-specific 8, tandem duplicate 1
chr13_-_11644806 0.55 ENSDART00000169953
dynactin 1b
chr25_+_10843985 0.55 ENSDART00000090386
ENSDART00000154975
si:ch211-147g22.4
chr12_-_45533034 0.55 ENSDART00000113004

chr21_-_2814709 0.54 ENSDART00000097664
semaphorin 4D
chr6_+_10450000 0.54 ENSDART00000151288
ENSDART00000187431
ENSDART00000192474
ENSDART00000188214
ENSDART00000184766
ENSDART00000190082
potassium channel, voltage gated eag related subfamily H, member 7
chr21_+_5915041 0.54 ENSDART00000151370
proline dehydrogenase (oxidase) 1a
chr15_-_37829160 0.54 ENSDART00000099425
chymotrypsin-like
chr9_-_22831836 0.54 ENSDART00000142585
nebulin
chr21_-_21096437 0.54 ENSDART00000186552
ankyrin 1, erythrocytic b
chr22_+_696931 0.54 ENSDART00000149712
ENSDART00000009756
G protein-coupled receptor 37 like 1a
chr8_+_17529151 0.54 ENSDART00000147760
si:ch73-70k4.1
chr22_+_31930650 0.54 ENSDART00000092090
dedicator of cytokinesis 3
chr6_-_39051319 0.54 ENSDART00000155093
tensin 2b
chr12_+_46960579 0.53 ENSDART00000149032
ornithine aminotransferase
chr10_+_24504292 0.53 ENSDART00000090059
microtubule associated tumor suppressor candidate 2a
chr24_+_12075009 0.53 ENSDART00000181141
chemokine (C-C motif) receptor 9b
chr14_+_9432627 0.53 ENSDART00000042727
si:dkeyp-86f7.4
chr1_+_45217619 0.53 ENSDART00000125037
si:ch211-239f4.1
chr7_-_38638276 0.52 ENSDART00000074463
six-cysteine containing astacin protease 4
chr12_-_15205087 0.52 ENSDART00000010068
sulfotransferase family 1, cytosolic sulfotransferase 6
chr5_+_70271799 0.52 ENSDART00000101316
zinc finger protein 618
chr17_-_1407593 0.52 ENSDART00000157622
ENSDART00000159458
zinc finger and BTB domain containing 42
chr15_+_30158652 0.52 ENSDART00000190682
nemo-like kinase, type 2
chr2_+_24638367 0.52 ENSDART00000088346
microtubule associated serine/threonine kinase 3a
chr22_+_2937485 0.52 ENSDART00000082222
ENSDART00000135507
ENSDART00000143258
centrosomal protein 19
chr16_-_48914757 0.51 ENSDART00000166740

chr18_+_5273953 0.51 ENSDART00000165073
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr16_-_13281380 0.51 ENSDART00000103882
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b
chr22_-_31059670 0.51 ENSDART00000022445
cullin-associated and neddylation-dissociated 2 (putative)
chr10_-_35236949 0.51 ENSDART00000145804
yippee-like 2a
chr8_-_33154677 0.51 ENSDART00000133300
zinc finger and BTB domain containing 34
chr6_-_53885514 0.51 ENSDART00000173812
ENSDART00000127144
calcium channel, voltage-dependent, alpha 2/delta subunit 2a
chr18_+_26719787 0.51 ENSDART00000141672
alpha-kinase 3a
chr5_-_13766651 0.51 ENSDART00000134064
MAX dimerization protein 1
chr10_+_21559605 0.51 ENSDART00000123648
ENSDART00000108584
protocadherin 1 alpha 3
protocadherin 1 alpha 3
chr21_+_4116437 0.50 ENSDART00000167791
ENSDART00000123759
Rap guanine nucleotide exchange factor (GEF) 1b
chr10_+_21576909 0.50 ENSDART00000168604
ENSDART00000166533
protocadherin 1 alpha 3

Network of associatons between targets according to the STRING database.

First level regulatory network of nfatc2a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0003322 pancreatic A cell development(GO:0003322)
0.4 1.2 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.3 1.3 GO:0006031 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.2 0.7 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.2 0.6 GO:0007414 axonal defasciculation(GO:0007414)
0.2 0.6 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.2 0.6 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.2 0.6 GO:0018315 establishment of synaptic specificity at neuromuscular junction(GO:0007529) molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.2 0.6 GO:0097377 interneuron axon guidance(GO:0097376) spinal cord interneuron axon guidance(GO:0097377) dorsal spinal cord interneuron axon guidance(GO:0097378)
0.2 0.9 GO:0030329 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.2 0.7 GO:0006114 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.2 0.5 GO:0010265 SCF complex assembly(GO:0010265)
0.2 0.5 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 0.6 GO:0044246 regulation of collagen metabolic process(GO:0010712) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246)
0.2 0.6 GO:0070166 enamel mineralization(GO:0070166)
0.2 0.6 GO:0010226 response to lithium ion(GO:0010226)
0.2 0.8 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.6 GO:2000815 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.1 0.6 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.4 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.1 0.6 GO:0006844 acyl carnitine transport(GO:0006844)
0.1 0.7 GO:0046103 adenosine catabolic process(GO:0006154) inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103)
0.1 0.5 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.1 0.7 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.7 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448) gamma-aminobutyric acid catabolic process(GO:0009450)
0.1 0.4 GO:0003250 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) endocardial cell development(GO:0060958) cell proliferation involved in heart valve development(GO:2000793)
0.1 0.5 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.6 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.1 0.6 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 1.1 GO:0009445 putrescine metabolic process(GO:0009445) putrescine biosynthetic process(GO:0009446)
0.1 0.3 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.1 0.6 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.3 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.5 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.5 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 0.3 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.1 0.6 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.1 0.4 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 0.3 GO:0051580 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
0.1 0.4 GO:0032801 receptor catabolic process(GO:0032801)
0.1 0.4 GO:0015677 copper ion import(GO:0015677)
0.1 0.4 GO:0015859 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.1 0.3 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.4 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.4 GO:0006590 thyroid hormone generation(GO:0006590)
0.1 0.5 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.1 1.8 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 0.4 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.1 0.4 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.4 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.3 GO:0072020 proximal straight tubule development(GO:0072020)
0.1 0.3 GO:0009097 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
0.1 0.3 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 0.4 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.3 GO:0019695 choline metabolic process(GO:0019695)
0.1 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.5 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.1 0.7 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.1 0.2 GO:0048917 posterior lateral line ganglion development(GO:0048917)
0.1 0.8 GO:0044206 pyrimidine-containing compound salvage(GO:0008655) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206)
0.1 1.5 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.1 0.5 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.1 0.2 GO:0042942 D-amino acid transport(GO:0042940) D-alanine transport(GO:0042941) D-serine transport(GO:0042942)
0.1 0.6 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.4 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.1 0.8 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.6 GO:0048790 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.1 0.2 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 0.5 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.1 0.3 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 0.3 GO:0051876 pigment granule dispersal(GO:0051876)
0.1 0.3 GO:0045109 intermediate filament organization(GO:0045109) intermediate filament bundle assembly(GO:0045110)
0.1 0.4 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.1 0.3 GO:0071387 cellular response to cortisol stimulus(GO:0071387)
0.1 1.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.2 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.1 0.5 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.1 0.3 GO:0001774 microglial cell activation(GO:0001774) regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.1 0.2 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 4.1 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.1 0.4 GO:0016572 histone phosphorylation(GO:0016572)
0.1 1.1 GO:0016203 muscle attachment(GO:0016203)
0.1 0.3 GO:0060402 cytosolic calcium ion transport(GO:0060401) calcium ion transport into cytosol(GO:0060402)
0.1 0.5 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 0.9 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.1 0.5 GO:0003428 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.1 0.2 GO:0060063 Spemann organizer formation at the embryonic shield(GO:0060063)
0.1 0.6 GO:0098900 regulation of action potential(GO:0098900)
0.1 0.7 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.2 GO:2000660 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.6 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.1 0.2 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.1 0.6 GO:0097090 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 0.3 GO:0099525 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.1 0.2 GO:0035973 aggrephagy(GO:0035973)
0.1 0.6 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.3 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.1 0.2 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 0.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.3 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1 0.4 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 0.3 GO:0036268 swimming(GO:0036268)
0.1 0.3 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.1 0.2 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.1 1.1 GO:0002574 thrombocyte differentiation(GO:0002574)
0.1 0.4 GO:0048680 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0 0.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 1.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.5 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.3 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.0 0.4 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.0 0.4 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.5 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 0.9 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.0 0.2 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.8 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 1.1 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 1.3 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.6 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.8 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 0.3 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.2 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.3 GO:0071233 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.0 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.6 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 0.3 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 1.2 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.1 GO:1904088 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.0 0.2 GO:0014909 smooth muscle cell migration(GO:0014909)
0.0 0.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.3 GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618) regulation of DNA-templated transcription in response to stress(GO:0043620)
0.0 0.1 GO:0032877 regulation of DNA endoreduplication(GO:0032875) positive regulation of DNA endoreduplication(GO:0032877) cell cycle comprising mitosis without cytokinesis(GO:0033301) DNA endoreduplication(GO:0042023)
0.0 0.5 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 1.9 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.1 GO:0034154 toll-like receptor 3 signaling pathway(GO:0034138) toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.7 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.3 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.3 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.5 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.0 0.5 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.9 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.2 GO:0050975 sensory perception of touch(GO:0050975)
0.0 0.3 GO:0042438 melanin biosynthetic process(GO:0042438)
0.0 0.2 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.0 0.8 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.8 GO:0001843 neural tube closure(GO:0001843)
0.0 0.3 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.0 0.1 GO:1901546 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.0 0.2 GO:0003262 endocardial progenitor cell migration to the midline involved in heart field formation(GO:0003262)
0.0 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.2 GO:0033119 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.4 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.5 GO:0021654 rhombomere boundary formation(GO:0021654)
0.0 0.5 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.5 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.0 0.1 GO:0048640 negative regulation of developmental growth(GO:0048640)
0.0 0.1 GO:0060547 negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.0 1.0 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.0 0.5 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 1.2 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 1.6 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.1 GO:0016103 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.5 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.1 GO:0010935 macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907)
0.0 6.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.1 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.4 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703) estrogen metabolic process(GO:0008210)
0.0 0.4 GO:0035860 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.1 GO:0032329 serine transport(GO:0032329) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.0 0.2 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 0.1 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.3 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 1.0 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.3 GO:2000406 positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
0.0 1.0 GO:0043113 receptor clustering(GO:0043113)
0.0 0.9 GO:0051294 establishment of spindle orientation(GO:0051294)
0.0 0.2 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.1 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.0 0.1 GO:0090311 regulation of protein deacetylation(GO:0090311)
0.0 0.2 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 0.5 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.2 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.0 0.1 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.3 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.7 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.2 GO:0001881 receptor recycling(GO:0001881)
0.0 0.0 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.6 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.7 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.2 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.2 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.0 1.5 GO:1990138 neuron projection extension(GO:1990138)
0.0 0.7 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.3 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.0 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 1.1 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.5 GO:1902667 regulation of axon guidance(GO:1902667)
0.0 0.5 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.4 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 2.8 GO:1990778 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.0 0.2 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.6 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:1902946 protein localization to early endosome(GO:1902946)
0.0 0.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.6 GO:0006826 iron ion transport(GO:0006826)
0.0 1.1 GO:0048017 inositol lipid-mediated signaling(GO:0048017)
0.0 0.1 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.0 0.4 GO:0060324 face development(GO:0060324)
0.0 0.3 GO:0097061 dendritic spine morphogenesis(GO:0060997) dendritic spine organization(GO:0097061)
0.0 0.2 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.3 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.8 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.2 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.1 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.9 GO:0007605 sensory perception of sound(GO:0007605)
0.0 3.6 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.9 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.1 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 0.2 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.0 0.4 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.7 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.0 0.1 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.0 0.2 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.2 GO:0046660 female sex differentiation(GO:0046660)
0.0 0.4 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 1.1 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.1 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 1.3 GO:0070509 calcium ion import(GO:0070509)
0.0 0.7 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.3 GO:0097192 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.0 0.4 GO:0035775 pronephric glomerulus morphogenesis(GO:0035775)
0.0 0.2 GO:0045471 response to ethanol(GO:0045471)
0.0 1.1 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.1 GO:0006501 macromitophagy(GO:0000423) C-terminal protein lipidation(GO:0006501)
0.0 0.2 GO:0001841 neural tube formation(GO:0001841)
0.0 0.5 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 0.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.3 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 1.1 GO:0017157 regulation of exocytosis(GO:0017157)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.1 GO:0043589 skin morphogenesis(GO:0043589) mesenchymal cell migration(GO:0090497)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0061709 reticulophagy(GO:0061709)
0.0 0.1 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168)
0.0 0.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 1.3 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.1 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.1 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.0 0.1 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.2 2.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.2 1.3 GO:0030428 cell septum(GO:0030428)
0.2 2.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 0.6 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.2 0.3 GO:0060076 excitatory synapse(GO:0060076)
0.1 0.4 GO:0033268 node of Ranvier(GO:0033268)
0.1 2.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.9 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.1 0.6 GO:0030315 T-tubule(GO:0030315)
0.1 0.4 GO:0043034 costamere(GO:0043034)
0.1 0.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.6 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.4 GO:0005845 mRNA cap binding complex(GO:0005845)
0.1 0.4 GO:0030897 HOPS complex(GO:0030897)
0.1 0.6 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 1.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 0.4 GO:0016586 RSC complex(GO:0016586)
0.1 0.2 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.2 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.0 0.7 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.5 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 1.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 3.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.7 GO:0005903 brush border(GO:0005903)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.7 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.9 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.1 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.0 0.3 GO:0032019 mitochondrial cloud(GO:0032019)
0.0 0.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.2 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 1.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.2 GO:1902636 kinociliary basal body(GO:1902636)
0.0 2.2 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 1.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.9 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.5 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.5 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 1.2 GO:0008305 integrin complex(GO:0008305)
0.0 0.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.4 GO:0044545 NSL complex(GO:0044545)
0.0 0.9 GO:0042641 actomyosin(GO:0042641)
0.0 3.0 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.2 GO:0001772 immunological synapse(GO:0001772)
0.0 0.4 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.2 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.2 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.2 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 0.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.3 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 1.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 2.1 GO:0099572 postsynaptic specialization(GO:0099572)
0.0 0.2 GO:0000792 heterochromatin(GO:0000792)
0.0 1.2 GO:0005604 basement membrane(GO:0005604)
0.0 1.5 GO:0005581 collagen trimer(GO:0005581)
0.0 3.8 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 3.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.1 GO:0005814 centriole(GO:0005814)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.7 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.1 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.2 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.5 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.2 GO:0030118 clathrin coat(GO:0030118)
0.0 1.4 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.2 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.1 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.2 GO:0043209 myelin sheath(GO:0043209)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0060175 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.2 0.6 GO:0004904 interferon receptor activity(GO:0004904)
0.2 0.6 GO:0070051 fibrinogen binding(GO:0070051)
0.2 2.5 GO:0030507 spectrin binding(GO:0030507)
0.2 0.6 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.2 0.7 GO:0097108 hedgehog family protein binding(GO:0097108)
0.2 1.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.2 0.9 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.2 0.8 GO:0050780 dopamine receptor binding(GO:0050780)
0.2 0.7 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.2 1.3 GO:0004100 chitin synthase activity(GO:0004100)
0.2 0.5 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.2 1.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.6 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.1 0.5 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 1.2 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.1 2.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.9 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.4 GO:0070883 pre-miRNA binding(GO:0070883)
0.1 0.9 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.8 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.6 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 0.3 GO:0009013 succinate-semialdehyde dehydrogenase (NAD+) activity(GO:0004777) succinate-semialdehyde dehydrogenase [NAD(P)+] activity(GO:0009013)
0.1 0.6 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.3 GO:0043621 protein self-association(GO:0043621)
0.1 0.5 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.1 0.4 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.4 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.1 0.4 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 0.6 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.4 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.6 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 1.0 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 0.2 GO:0052833 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.5 GO:0019809 spermidine binding(GO:0019809)
0.1 2.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.5 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.3 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697) type II activin receptor binding(GO:0070699)
0.1 1.3 GO:0045159 myosin II binding(GO:0045159)
0.1 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.3 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.1 0.3 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 0.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.4 GO:0032052 bile acid binding(GO:0032052)
0.1 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.5 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.2 GO:0048030 disaccharide binding(GO:0048030)
0.1 1.0 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 0.5 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 0.5 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.6 GO:0004568 chitinase activity(GO:0004568)
0.1 0.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.1 0.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.2 GO:0004903 growth hormone receptor activity(GO:0004903)
0.1 0.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 2.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.1 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.9 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0045547 dehydrodolichyl diphosphate synthase activity(GO:0045547)
0.0 1.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.1 GO:0008483 transaminase activity(GO:0008483)
0.0 0.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 3.0 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.6 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.8 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.3 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.5 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 1.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 0.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.6 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.3 GO:0070728 leucine binding(GO:0070728)
0.0 0.6 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 1.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0070052 collagen V binding(GO:0070052)
0.0 0.2 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.0 1.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.3 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.4 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.5 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 1.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.2 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.6 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 1.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0070336 flap-structured DNA binding(GO:0070336)
0.0 0.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.6 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0005542 folic acid binding(GO:0005542)
0.0 0.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 1.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.7 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.3 GO:1990239 steroid hormone binding(GO:1990239)
0.0 0.2 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 1.2 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 2.1 GO:0008201 heparin binding(GO:0008201)
0.0 1.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.4 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.3 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.3 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.3 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.0 0.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.2 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.0 0.8 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.4 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 1.0 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.4 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.3 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.0 0.1 GO:0030791 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.0 0.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 2.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0022842 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.5 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.3 GO:0042805 actinin binding(GO:0042805) muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.0 0.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.4 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 1.3 GO:0003774 motor activity(GO:0003774)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.3 GO:0017022 myosin binding(GO:0017022)
0.0 0.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 3.3 GO:0008017 microtubule binding(GO:0008017)
0.0 0.0 GO:0015369 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.0 0.1 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.4 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 3.6 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 1.3 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.4 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.1 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.3 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.4 GO:0019957 C-C chemokine binding(GO:0019957)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.2 PID FOXO PATHWAY FoxO family signaling
0.0 0.2 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.3 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.0 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.6 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.1 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.2 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.3 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.2 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.0 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.4 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.2 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.2 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.2 PID ARF 3PATHWAY Arf1 pathway
0.0 0.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.4 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.0 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 0.9 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 0.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 0.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 0.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 0.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 0.8 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.1 0.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 0.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.5 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 1.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.7 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 1.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 1.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.2 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.2 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.1 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis