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PRJEB1986: zebrafish developmental stages transcriptome

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Results for neurod1

Z-value: 1.75

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Transcription factors associated with neurod1

Gene Symbol Gene ID Gene Info
ENSDARG00000019566 neuronal differentiation 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
neurod1dr11_v1_chr9_-_44295071_442950710.598.1e-03Click!

Activity profile of neurod1 motif

Sorted Z-values of neurod1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_51065048 14.72 ENSDART00000168085

chr25_+_37130450 7.56 ENSDART00000183358
si:ch1073-174d20.1
chr3_-_50443607 7.03 ENSDART00000074036
recoverin a
chr8_+_21376290 6.52 ENSDART00000136765
elastase 2
chr12_+_46967789 6.48 ENSDART00000114866
ornithine aminotransferase
chr6_-_13783604 6.40 ENSDART00000149536
ENSDART00000041269
ENSDART00000150102
crystallin, beta A2a
chr5_-_26118855 6.21 ENSDART00000009028
elastase 3 like
chr23_+_2778813 5.67 ENSDART00000142621
DNA topoisomerase I
chr2_+_31475772 5.67 ENSDART00000130722
calcium channel, voltage-dependent, beta 2b
chr18_+_46773198 5.48 ENSDART00000174647

chr20_-_25522911 5.19 ENSDART00000063058
cytochrome P450, family 2, subfamily N, polypeptide 13
chr13_-_7031033 5.12 ENSDART00000193211

chr13_+_1369003 5.09 ENSDART00000146082
interferon gamma receptor 1
chr17_-_51829310 5.02 ENSDART00000154544
numb homolog (Drosophila)
chr16_+_52512025 4.63 ENSDART00000056095
fatty acid binding protein 10a, liver basic
chr14_-_33613794 4.57 ENSDART00000010022
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr21_+_10739846 4.28 ENSDART00000084011
complexin 4a
chr9_+_56422311 4.27 ENSDART00000171958
G protein-coupled receptor 39
chr6_-_9565526 4.19 ENSDART00000151470
mitogen-activated protein kinase kinase kinase 2
chr7_+_39389273 4.09 ENSDART00000191298
troponin I type 2b (skeletal, fast), tandem duplicate 2
chr20_-_44576949 4.01 ENSDART00000148639
UBX domain protein 2A
chr9_-_1200187 4.00 ENSDART00000158760
INO80 complex subunit Da
chr6_-_35487413 4.00 ENSDART00000102461
regulator of G protein signaling 8
chr4_-_1324141 3.98 ENSDART00000180720
pleiotrophin
chr18_+_45550783 3.79 ENSDART00000138075
kinesin family member C3
chr19_-_38830582 3.72 ENSDART00000189966
ENSDART00000183055
adhesion G protein-coupled receptor B2
chr16_-_29334672 3.65 ENSDART00000162835
brevican
chr21_+_6212844 3.64 ENSDART00000150301
formin binding protein 1b
chr19_-_27261102 3.48 ENSDART00000143919
gamma-aminobutyric acid (GABA) B receptor, 1b
chr23_+_20563779 3.47 ENSDART00000146008
CaM kinase-like vesicle-associated, like
chr6_+_46341306 3.44 ENSDART00000111905

chr2_+_31476065 3.44 ENSDART00000049219
calcium channel, voltage-dependent, beta 2b
chr21_-_14630831 3.42 ENSDART00000132142
ENSDART00000089967
calcium channel, voltage-dependent, N type, alpha 1B subunit, b
chr25_-_554142 3.40 ENSDART00000028997
myosin IXAb
chr14_+_40874608 3.40 ENSDART00000168448
si:ch211-106m9.1
chr12_-_14922955 3.38 ENSDART00000002078
neurogenic differentiation 2
chr20_-_39273505 3.29 ENSDART00000153114
clusterin
chr11_-_28911172 3.25 ENSDART00000168493
immunoglobin superfamily, member 21a
chr1_-_29045426 3.21 ENSDART00000019770
glycoprotein M6Ba
chr22_-_33679277 3.16 ENSDART00000169948

chr19_-_6134802 3.15 ENSDART00000140051
capicua transcriptional repressor a
chr12_+_31744217 3.12 ENSDART00000190361
si:dkey-49c17.3
chr3_-_60886984 3.09 ENSDART00000170974
phosphatidylinositol transfer protein, cytoplasmic 1
chr17_-_51202339 3.07 ENSDART00000167117
si:ch1073-469d17.2
chr2_-_37888429 3.05 ENSDART00000183277
mannose binding lectin 2
chr9_-_22831836 3.04 ENSDART00000142585
nebulin
chr11_-_37359416 3.04 ENSDART00000159184
ELKS/RAB6-interacting/CAST family member 2
chr21_-_43952958 3.04 ENSDART00000039571
calcium/calmodulin-dependent protein kinase II alpha
chr11_-_7050825 3.01 ENSDART00000179749
si:ch211-253b8.5
chr23_+_5465806 2.93 ENSDART00000149434
ENSDART00000148506
tubby like protein 1a
chr6_+_21740672 2.88 ENSDART00000193734
lipoma HMGIC fusion partner-like 4a
chr19_+_9174166 2.87 ENSDART00000104637
ENSDART00000150968
si:ch211-81a5.8
chr14_+_15622817 2.84 ENSDART00000158624
si:dkey-203a12.9
chr10_+_29431529 2.82 ENSDART00000158154
discs, large homolog 2 (Drosophila)
chr19_-_38872650 2.77 ENSDART00000146641
adhesion G protein-coupled receptor B2
chr14_-_21219659 2.75 ENSDART00000089867
protein phosphatase 2, regulatory subunit B, gamma b
chr13_-_30027730 2.73 ENSDART00000044009
stearoyl-CoA desaturase b
chr18_+_660578 2.72 ENSDART00000161203
si:dkey-205h23.2
chr24_-_1657276 2.69 ENSDART00000168131
si:ch73-378g22.1
chr14_+_32838110 2.67 ENSDART00000158077
arrestin 3b, retinal (X-arrestin)
chr10_-_24362775 2.65 ENSDART00000182104
phosphatidylinositol transfer protein, alpha b
chr21_+_13353263 2.62 ENSDART00000114677
si:ch73-62l21.1
chr1_-_40227166 2.60 ENSDART00000146680
si:ch211-113e8.3
chr12_-_35949936 2.59 ENSDART00000192583

chr23_-_5032587 2.57 ENSDART00000163903
potassium voltage-gated channel, shaker-related subfamily, member 2b
chr9_-_9980704 2.56 ENSDART00000130243
ENSDART00000193475
UDP glucuronosyltransferase 1 family a, b
chr20_-_18731268 2.56 ENSDART00000183893
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr14_+_32837914 2.55 ENSDART00000158888
arrestin 3b, retinal (X-arrestin)
chr8_-_26609259 2.54 ENSDART00000027301
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr3_+_23092762 2.53 ENSDART00000142884
ENSDART00000024136
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a
chr11_-_32723851 2.52 ENSDART00000155592
protocadherin 17
chr21_-_13085242 2.52 ENSDART00000044504
zgc:109965
chr2_+_50626476 2.52 ENSDART00000018150
neuronal differentiation 6b
chr22_+_17205608 2.51 ENSDART00000181267
RAB3B, member RAS oncogene family
chr13_+_3954540 2.49 ENSDART00000092646
leucine rich repeat containing 73
chr5_-_38342992 2.48 ENSDART00000140337
misshapen-like kinase 1
chr7_+_30823749 2.44 ENSDART00000085661
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr8_-_3716734 2.42 ENSDART00000172966
BICD family like cargo adaptor 1
chr21_-_16632808 2.39 ENSDART00000172645
unc-5 netrin receptor Da
chr20_-_39273987 2.37 ENSDART00000127173
clusterin
chr6_-_57426097 2.36 ENSDART00000171531
zinc finger, NFX1-type containing 1
chr6_+_9175886 2.36 ENSDART00000165333
si:ch211-207l14.1
chr25_+_7670683 2.34 ENSDART00000040275
potassium inwardly-rectifying channel, subfamily J, member 11, like
chr24_+_29449690 2.32 ENSDART00000105743
ENSDART00000193556
ENSDART00000145816
netrin g1a
chr2_+_5948534 2.31 ENSDART00000124324
ENSDART00000176461
solute carrier family 1 (glutamate transporter), member 7a
chr1_-_14233815 2.29 ENSDART00000044896
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr5_+_62611400 2.26 ENSDART00000132054
active BCR-related
chr8_+_7359294 2.25 ENSDART00000121708
proprotein convertase subtilisin/kexin type 1 inhibitor, like
chr10_-_44508249 2.24 ENSDART00000160018
dual specificity phosphatase 26
chr8_-_44868020 2.24 ENSDART00000142712
calcium channel, voltage-dependent, L type, alpha 1F subunit a
chr11_+_6159595 2.24 ENSDART00000178367
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr20_+_1412193 2.22 ENSDART00000064419
liver-enriched gene 1, tandem duplicate 1
chr23_+_5470967 2.19 ENSDART00000110522
ENSDART00000149050
tubby like protein 1a
chr3_+_50069610 2.19 ENSDART00000056619
zgc:103625
chr18_-_38088099 2.19 ENSDART00000146120
leucine zipper protein 2
chr21_+_39100289 2.18 ENSDART00000075958
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr15_+_3284416 2.17 ENSDART00000187665
ENSDART00000171723
forkhead box O1 a
chr16_+_21738194 2.17 ENSDART00000163688
Danio rerio si:ch211-154o6.4 (si:ch211-154o6.4), mRNA.
chr15_+_9053059 2.16 ENSDART00000012039
protein phosphatase, Mg2+/Mn2+ dependent, 1Na (putative)
chr18_+_9635178 2.16 ENSDART00000183486
piccolo presynaptic cytomatrix protein b
chr18_+_12147971 2.15 ENSDART00000162067
ENSDART00000168386
FYVE, RhoGEF and PH domain containing 4a
chr17_-_45040813 2.15 ENSDART00000075514
ectonucleoside triphosphate diphosphohydrolase 5a
chr11_-_28157129 2.13 ENSDART00000103450
lactamase, beta-like 1b
chr21_+_27382893 2.13 ENSDART00000005682
actinin alpha 3a
chr15_-_28094256 2.12 ENSDART00000142041
ENSDART00000132153
ENSDART00000146657
ENSDART00000048720
crystallin, beta A1a
chr5_-_40190949 2.12 ENSDART00000175588
WD repeat and FYVE domain containing 3
chr8_-_49935358 2.12 ENSDART00000159782
ENSDART00000156841
ATP/GTP binding protein 1

chr6_-_27139396 2.10 ENSDART00000055848
zgc:103559
chr24_-_17444067 2.08 ENSDART00000155843
contactin associated protein like 2a
chr7_+_10351038 2.06 ENSDART00000173256
si:cabz01029535.1
chr21_+_8427059 2.06 ENSDART00000143151
DENN/MADD domain containing 1A
chr13_-_44285793 2.05 ENSDART00000167383

chr15_+_30158652 2.05 ENSDART00000190682
nemo-like kinase, type 2
chr6_+_22597362 2.04 ENSDART00000131242
cytoglobin 2
chr13_+_228045 2.04 ENSDART00000161091
zgc:64201
chr18_-_38087875 2.04 ENSDART00000111301
leucine zipper protein 2
chr6_+_54538948 2.04 ENSDART00000149270
tubby like protein 1b
chr5_+_21891305 2.03 ENSDART00000136788
si:ch73-92i20.1
chr5_-_18513950 2.02 ENSDART00000145878
si:dkey-215k6.1
chr25_+_4541211 2.02 ENSDART00000129978
patatin-like phospholipase domain containing 2
chr5_-_23280098 2.01 ENSDART00000126540
ENSDART00000051533
proteolipid protein 1b
chr11_-_43226255 2.00 ENSDART00000172929
spectrin, beta, non-erythrocytic 1
chr10_-_17103651 1.98 ENSDART00000108959
ring finger protein 208
chr25_-_16818978 1.98 ENSDART00000104140
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr16_-_31644545 1.94 ENSDART00000181634

chr6_-_43449013 1.92 ENSDART00000122423
2-epi-5-epi-valiolone synthase
chr15_+_42933236 1.92 ENSDART00000167763
solute carrier family 8 (sodium/calcium exchanger), member 2b
chr3_+_26144765 1.92 ENSDART00000146267
ENSDART00000043932
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr20_-_25669813 1.91 ENSDART00000153118
si:dkeyp-117h8.2
chr14_-_4556896 1.91 ENSDART00000044678
ENSDART00000192863
gamma-aminobutyric acid type A receptor alpha2 subunit
chr15_-_29598679 1.88 ENSDART00000155153
si:ch211-207n23.2
chr5_+_69950882 1.88 ENSDART00000097359
DnaJ (Hsp40) homolog, subfamily C , member 25
chr5_-_51819027 1.88 ENSDART00000164267
homer scaffolding protein 1b
chr7_+_32722227 1.88 ENSDART00000126565
si:ch211-150g13.3
chr9_+_31795343 1.86 ENSDART00000139584
integrin, beta-like 1
chr25_-_20258508 1.85 ENSDART00000133860
ENSDART00000006840
ENSDART00000173434
dynamin 1-like
chr7_+_26224211 1.85 ENSDART00000173999
VGF nerve growth factor inducible
chr10_-_5847904 1.85 ENSDART00000161096
ankyrin repeat domain 55
chr23_-_1660708 1.84 ENSDART00000175138

chr19_-_10373630 1.84 ENSDART00000131517
si:ch211-232m10.6
chr3_+_50312422 1.84 ENSDART00000157689
growth arrest-specific 7a
chr22_-_21897203 1.82 ENSDART00000158501
ENSDART00000105566
ENSDART00000136795
guanine nucleotide binding protein (G protein), alpha 11a (Gq class)
chr9_+_25096500 1.82 ENSDART00000135074
ENSDART00000180436
ENSDART00000108629
leucine-rich repeats and calponin homology (CH) domain containing 1
chr19_+_43669122 1.78 ENSDART00000139151
si:ch211-193k19.1
chr17_+_32360673 1.78 ENSDART00000155519
si:ch211-139d20.3
chr8_+_8735285 1.78 ENSDART00000165655
ELK1, member of ETS oncogene family
chr7_+_29133321 1.78 ENSDART00000052346
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b
chr21_-_22737228 1.77 ENSDART00000151366
F-box protein 40, tandem duplicate 2
chr1_-_22370660 1.77 ENSDART00000127506
si:ch73-380n15.2
chr17_-_25397558 1.76 ENSDART00000182052
family with sequence similarity 167, member B
chr9_+_56422517 1.76 ENSDART00000168620
G protein-coupled receptor 39
chr1_+_21937201 1.76 ENSDART00000087729
lysine (K)-specific demethylase 4C
chr3_+_33340939 1.74 ENSDART00000128786
peptide YYa
chr5_-_33769211 1.74 ENSDART00000133504
DAB2 interacting protein b
chr6_-_51101834 1.73 ENSDART00000092493
protein tyrosine phosphatase, receptor type, t
chr3_+_50310684 1.73 ENSDART00000112152
growth arrest-specific 7a
chr13_+_28854438 1.72 ENSDART00000193407
ENSDART00000189554

chr13_+_3954715 1.71 ENSDART00000182477
ENSDART00000192142
ENSDART00000190962
leucine rich repeat containing 73
chr10_-_24371312 1.71 ENSDART00000149362
phosphatidylinositol transfer protein, alpha b
chr5_+_3501859 1.71 ENSDART00000080486
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1
chr13_-_27916439 1.71 ENSDART00000139081
ENSDART00000087097
opioid growth factor receptor-like 1
chr10_-_29120515 1.70 ENSDART00000162016
ENSDART00000149140
zona pellucida-like domain containing 1a
chr8_+_36666789 1.70 ENSDART00000144255
MAGI family member, X-linked b
chr6_-_35401282 1.69 ENSDART00000127612
regulator of G protein signaling 5a
chr7_-_28463106 1.69 ENSDART00000137799
tripartite motif containing 66
chr6_+_39493864 1.67 ENSDART00000086263
methyltransferase like 7A
chr17_-_44584811 1.67 ENSDART00000165059
ENSDART00000165252
solute carrier family 35, member F4
chr23_+_21544227 1.64 ENSDART00000140253
Rho guanine nucleotide exchange factor (GEF) 10-like b
chr24_-_38644937 1.64 ENSDART00000170194
solute carrier family 6, member 16b
chr4_-_20181964 1.62 ENSDART00000022539
fibrinogen-like 2a
chr18_+_10840071 1.61 ENSDART00000014496
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr24_+_32472155 1.59 ENSDART00000098859
neuronal differentiation 6a
chr12_+_21525496 1.58 ENSDART00000152974
carbonic anhydrase Xa
chr2_+_33541928 1.57 ENSDART00000162852

chr25_+_33849647 1.56 ENSDART00000121449
RAR-related orphan receptor A, paralog a
chr14_-_21218891 1.55 ENSDART00000158294
protein phosphatase 2, regulatory subunit B, gamma b
chr14_+_40641350 1.54 ENSDART00000074506
tenomodulin
chr13_-_40499296 1.54 ENSDART00000158338
Danio rerio cyclin and CBS domain divalent metal cation transport mediator 1 (cnnm1), mRNA.
chr19_+_43684376 1.54 ENSDART00000051723
si:ch211-193k19.1
chr11_+_6902946 1.53 ENSDART00000144006
CREB regulated transcription coactivator 1b
chr25_-_16818380 1.53 ENSDART00000155401
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr17_-_52579709 1.52 ENSDART00000156806
ribosomal protein S6 kinase-like 1
chr9_+_49712868 1.49 ENSDART00000192969
ENSDART00000183310
cysteine and serine rich nuclear protein 3
chr9_+_28693592 1.49 ENSDART00000110198
zgc:162780
chr18_+_48576527 1.49 ENSDART00000167555
potassium inwardly-rectifying channel, subfamily J, member 5
chr2_+_30878864 1.48 ENSDART00000009326
opioid receptor, kappa 1
chr18_+_3634652 1.48 ENSDART00000159913
leucine-rich repeats and calponin homology (CH) domain containing 3
chr18_+_15795748 1.46 ENSDART00000147024
ENSDART00000137681
nudix (nucleoside diphosphate linked moiety X)-type motif 4a
chr3_+_22242269 1.45 ENSDART00000168970
sodium channel, voltage-gated, type IV, alpha, b
chr1_+_32521469 1.45 ENSDART00000113818
ENSDART00000152580
neuroligin 4a
chr13_-_16226312 1.44 ENSDART00000163952
zgc:110045
chr7_-_23996133 1.44 ENSDART00000173761
si:dkey-183c6.8
chr6_-_46565466 1.43 ENSDART00000153673
potassium voltage-gated channel, Shab-related subfamily, member 1
chr6_-_35032792 1.42 ENSDART00000168256
discoidin domain receptor tyrosine kinase 2a
chr5_+_37854685 1.42 ENSDART00000051222
ENSDART00000185283
preproinsulin
chr2_-_37478418 1.41 ENSDART00000146103
death-associated protein kinase 3
chr11_+_29999414 1.40 ENSDART00000161160
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr5_-_52243424 1.40 ENSDART00000159078
endoplasmic reticulum aminopeptidase 2
chr19_-_9882821 1.39 ENSDART00000147128
calcium channel, voltage-dependent, gamma subunit 7a
chr5_+_20147830 1.39 ENSDART00000098727
SV2 related protein a

Network of associatons between targets according to the STRING database.

First level regulatory network of neurod1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.7 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
1.1 3.2 GO:0051580 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
0.9 3.5 GO:0035095 behavioral response to nicotine(GO:0035095)
0.8 3.4 GO:0060074 synapse maturation(GO:0060074)
0.7 2.9 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.7 6.5 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.7 2.1 GO:0000256 allantoin catabolic process(GO:0000256) purine nucleobase catabolic process(GO:0006145)
0.7 2.7 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.7 3.4 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.6 7.0 GO:0036368 cone photoresponse recovery(GO:0036368)
0.6 1.8 GO:1990868 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.6 2.4 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.6 2.8 GO:1901908 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.5 2.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.5 3.0 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.5 2.0 GO:0010896 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.5 1.9 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.4 3.1 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.4 5.2 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.4 4.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.4 2.1 GO:0099612 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.4 3.3 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.4 1.2 GO:0097264 self proteolysis(GO:0097264)
0.4 1.2 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.4 1.1 GO:1901546 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.4 0.4 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.4 1.9 GO:1903146 regulation of mitophagy(GO:1903146)
0.4 1.5 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.4 1.4 GO:0048521 positive regulation of epithelial cell differentiation(GO:0030858) negative regulation of behavior(GO:0048521) negative regulation of feeding behavior(GO:2000252)
0.3 2.4 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.3 1.0 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.3 5.7 GO:0006265 DNA topological change(GO:0006265)
0.3 3.3 GO:0099558 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.3 2.0 GO:0048745 smooth muscle tissue development(GO:0048745)
0.3 0.8 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.3 1.1 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.3 1.9 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.3 0.8 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.2 9.9 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.2 4.2 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.2 4.0 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.2 1.2 GO:0060402 cytosolic calcium ion transport(GO:0060401) calcium ion transport into cytosol(GO:0060402)
0.2 1.8 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.2 2.2 GO:1990402 embryonic liver development(GO:1990402)
0.2 2.2 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.2 2.4 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.2 2.2 GO:1990709 presynaptic active zone assembly(GO:1904071) presynaptic active zone organization(GO:1990709)
0.2 2.1 GO:0055062 phosphate ion homeostasis(GO:0055062) trivalent inorganic anion homeostasis(GO:0072506)
0.2 1.0 GO:0036371 protein localization to T-tubule(GO:0036371)
0.2 0.6 GO:0035973 aggrephagy(GO:0035973)
0.2 0.8 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.2 1.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.2 0.6 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.2 6.5 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.2 5.9 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.2 0.8 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.2 2.7 GO:0098508 endothelial to hematopoietic transition(GO:0098508)
0.2 0.6 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 0.7 GO:0002164 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.1 1.4 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 6.6 GO:0061512 protein localization to cilium(GO:0061512)
0.1 6.5 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 0.4 GO:0060262 N-terminal protein palmitoylation(GO:0006500) negative regulation of lipoprotein metabolic process(GO:0050748) regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.1 2.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 2.3 GO:0051764 actin crosslink formation(GO:0051764)
0.1 1.4 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 1.4 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.1 1.2 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.9 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 1.7 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 1.8 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 0.3 GO:0042420 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.1 2.0 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.1 5.2 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.1 1.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 1.0 GO:0061709 reticulophagy(GO:0061709)
0.1 2.0 GO:0015671 oxygen transport(GO:0015671)
0.1 1.5 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 0.8 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479)
0.1 1.9 GO:0098703 inorganic cation import into cell(GO:0098659) calcium ion import across plasma membrane(GO:0098703) inorganic ion import into cell(GO:0099587) calcium ion import into cell(GO:1990035)
0.1 4.1 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 1.9 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 1.8 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.1 0.6 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.1 5.7 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.1 0.9 GO:0021576 hindbrain formation(GO:0021576)
0.1 2.9 GO:0046847 filopodium assembly(GO:0046847)
0.1 1.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 2.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 2.2 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 2.5 GO:0003323 type B pancreatic cell development(GO:0003323)
0.1 0.4 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 2.3 GO:0070831 basement membrane assembly(GO:0070831)
0.1 1.9 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 1.4 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.1 0.8 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 5.8 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.9 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 1.7 GO:0007631 feeding behavior(GO:0007631)
0.1 1.0 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 2.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 1.2 GO:0007398 ectoderm development(GO:0007398)
0.1 0.5 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.1 0.5 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.1 0.7 GO:0045777 positive regulation of blood pressure(GO:0045777)
0.1 2.9 GO:0036269 swimming behavior(GO:0036269)
0.1 5.0 GO:0070509 calcium ion import(GO:0070509)
0.1 4.1 GO:0050919 negative chemotaxis(GO:0050919)
0.1 2.3 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1 2.5 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 1.4 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.1 1.9 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.1 7.3 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 0.4 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 0.2 GO:2000303 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1 0.4 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.3 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.9 GO:0050927 regulation of positive chemotaxis(GO:0050926) positive regulation of positive chemotaxis(GO:0050927) induction of positive chemotaxis(GO:0050930)
0.1 1.4 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 0.1 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 4.1 GO:0030042 actin filament depolymerization(GO:0030042)
0.0 0.6 GO:0051928 positive regulation of calcium ion transport(GO:0051928)
0.0 0.3 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.0 3.0 GO:0003146 heart jogging(GO:0003146)
0.0 1.0 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.2 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.0 0.9 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.3 GO:0090311 regulation of histone deacetylation(GO:0031063) regulation of protein deacetylation(GO:0090311)
0.0 0.8 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.4 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 1.1 GO:0021587 cerebellum morphogenesis(GO:0021587)
0.0 2.5 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 1.3 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 2.1 GO:0015914 phospholipid transport(GO:0015914)
0.0 4.7 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.4 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.4 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 1.4 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 1.9 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.1 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 4.1 GO:0006814 sodium ion transport(GO:0006814)
0.0 0.9 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 1.1 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.0 0.6 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.9 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.9 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.4 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.4 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0036076 ligamentous ossification(GO:0036076)
0.0 0.6 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.3 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.3 GO:0031638 zymogen activation(GO:0031638)
0.0 2.6 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.4 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0048669 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.6 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.4 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.3 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 1.3 GO:0006865 amino acid transport(GO:0006865)
0.0 0.2 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 1.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.5 GO:0042113 B cell activation(GO:0042113)
0.0 1.4 GO:0010942 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.0 0.5 GO:0001764 neuron migration(GO:0001764)
0.0 0.6 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.1 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 7.3 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)
0.0 0.2 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.4 GO:0032944 regulation of mononuclear cell proliferation(GO:0032944) regulation of T cell proliferation(GO:0042129) regulation of lymphocyte proliferation(GO:0050670) regulation of leukocyte proliferation(GO:0070663)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0060077 inhibitory synapse(GO:0060077)
0.6 5.7 GO:0042583 chromaffin granule(GO:0042583)
0.5 1.9 GO:0031673 H zone(GO:0031673)
0.4 3.5 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.4 2.0 GO:0008091 spectrin(GO:0008091)
0.3 1.1 GO:0043291 RAVE complex(GO:0043291)
0.3 2.1 GO:0033010 paranodal junction(GO:0033010)
0.2 6.2 GO:0043195 terminal bouton(GO:0043195)
0.2 8.9 GO:0043204 perikaryon(GO:0043204)
0.2 2.2 GO:0098982 GABA-ergic synapse(GO:0098982)
0.2 2.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.2 14.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 3.3 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.2 1.1 GO:0043194 axon initial segment(GO:0043194)
0.2 2.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 2.5 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 1.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 1.0 GO:0030315 T-tubule(GO:0030315)
0.1 1.4 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.7 GO:0071439 clathrin complex(GO:0071439)
0.1 2.0 GO:0043209 myelin sheath(GO:0043209)
0.1 3.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 2.3 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.1 0.6 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 4.1 GO:0005861 troponin complex(GO:0005861)
0.1 0.7 GO:0016586 RSC complex(GO:0016586)
0.1 0.3 GO:0044297 cell body(GO:0044297)
0.1 0.7 GO:0044295 axonal growth cone(GO:0044295)
0.1 6.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 3.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 2.5 GO:0030426 growth cone(GO:0030426)
0.1 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 4.4 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.4 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.9 GO:0008305 integrin complex(GO:0008305)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.8 GO:0005811 lipid particle(GO:0005811)
0.0 1.4 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 1.9 GO:0042383 sarcolemma(GO:0042383)
0.0 3.9 GO:0005884 actin filament(GO:0005884)
0.0 2.5 GO:0030018 Z disc(GO:0030018)
0.0 4.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 3.3 GO:0045202 synapse(GO:0045202)
0.0 1.9 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.7 GO:0060170 ciliary membrane(GO:0060170)
0.0 2.7 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.3 GO:0032420 stereocilium(GO:0032420)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 2.2 GO:0099572 postsynaptic specialization(GO:0099572)
0.0 1.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 1.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.3 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.1 GO:0030130 trans-Golgi network transport vesicle membrane(GO:0012510) clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.9 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.3 GO:0016324 apical plasma membrane(GO:0016324)
0.0 2.1 GO:0030880 RNA polymerase complex(GO:0030880)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 2.6 GO:0005912 adherens junction(GO:0005912)
0.0 19.7 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.1 GO:0098794 postsynapse(GO:0098794)
0.0 6.1 GO:0097458 neuron part(GO:0097458)
0.0 1.3 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.6 GO:0032052 bile acid binding(GO:0032052)
0.7 2.7 GO:0032896 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.6 4.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.6 1.8 GO:0042166 neurotransmitter binding(GO:0042165) acetylcholine binding(GO:0042166)
0.6 4.6 GO:0034452 dynactin binding(GO:0034452)
0.6 2.8 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.5 2.1 GO:0050897 cobalt ion binding(GO:0050897)
0.4 5.7 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.4 3.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.4 11.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.4 1.9 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.4 1.8 GO:0051430 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.4 3.2 GO:0004985 opioid receptor activity(GO:0004985)
0.3 1.7 GO:0031843 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.3 1.4 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.3 2.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.3 5.5 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.3 2.0 GO:0098809 nitrite reductase activity(GO:0098809)
0.3 1.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.3 2.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 1.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.3 0.8 GO:0097643 amylin receptor activity(GO:0097643)
0.3 1.0 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.2 1.2 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.2 0.7 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.2 2.4 GO:0005042 netrin receptor activity(GO:0005042)
0.2 0.9 GO:0042609 CD4 receptor binding(GO:0042609)
0.2 1.9 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.2 0.8 GO:0003796 lysozyme activity(GO:0003796)
0.2 1.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 2.0 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.2 1.8 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.2 9.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.2 0.8 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.2 0.8 GO:0071253 connexin binding(GO:0071253)
0.2 1.7 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.2 0.7 GO:0070052 collagen V binding(GO:0070052)
0.2 6.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 2.5 GO:0038191 neuropilin binding(GO:0038191)
0.2 1.2 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.2 2.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 1.4 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.2 3.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.9 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 1.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.1 2.9 GO:0050811 GABA receptor binding(GO:0050811)
0.1 2.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 1.3 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.1 3.4 GO:0051787 misfolded protein binding(GO:0051787)
0.1 2.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.8 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 2.0 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 9.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 3.8 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 1.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.2 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.7 GO:0004960 thromboxane receptor activity(GO:0004960)
0.1 5.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 2.6 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 6.5 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.1 0.4 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.6 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.3 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.1 0.4 GO:0047611 tubulin deacetylase activity(GO:0042903) acetylspermidine deacetylase activity(GO:0047611)
0.1 1.4 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.9 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 0.8 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.8 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 0.8 GO:0031628 opioid receptor binding(GO:0031628)
0.1 4.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 3.7 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 1.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.1 GO:0005222 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.3 GO:0008887 glycerate kinase activity(GO:0008887)
0.1 1.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 5.2 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 2.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 2.0 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.9 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.6 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.8 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.1 1.1 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.1 1.0 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.9 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 3.8 GO:0005178 integrin binding(GO:0005178)
0.1 1.0 GO:0048495 Roundabout binding(GO:0048495)
0.1 6.5 GO:0019905 syntaxin binding(GO:0019905)
0.1 0.7 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 1.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 0.5 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.1 1.2 GO:0004875 complement receptor activity(GO:0004875)
0.1 0.6 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 1.9 GO:0030145 manganese ion binding(GO:0030145)
0.1 1.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 4.1 GO:0008201 heparin binding(GO:0008201)
0.1 12.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.0 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 1.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.4 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.7 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 5.9 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 17.3 GO:0051015 actin filament binding(GO:0051015)
0.0 1.5 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 1.1 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.4 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 1.0 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 1.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 1.1 GO:0098632 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.6 GO:0071949 FAD binding(GO:0071949)
0.0 0.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 5.6 GO:0015293 symporter activity(GO:0015293)
0.0 2.6 GO:0045296 cadherin binding(GO:0045296)
0.0 2.6 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.5 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.4 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.0 0.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.7 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.5 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.8 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 16.2 GO:0004672 protein kinase activity(GO:0004672)
0.0 5.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 1.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.3 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.1 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.3 GO:0015248 sterol transporter activity(GO:0015248)
0.0 1.7 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 1.1 GO:0005179 hormone activity(GO:0005179)
0.0 6.6 GO:0004930 G-protein coupled receptor activity(GO:0004930)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.2 7.0 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.2 3.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 5.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 4.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 3.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 6.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 3.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 3.6 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 1.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 0.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 2.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.7 PID AURORA A PATHWAY Aurora A signaling
0.0 0.7 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.7 5.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.6 6.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.3 2.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.3 3.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.3 3.8 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 0.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.2 3.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 5.0 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.2 1.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 2.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.7 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 1.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 3.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.2 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 1.8 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 4.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 5.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 0.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.4 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1 0.9 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 5.4 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 1.9 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
0.1 1.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 0.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 2.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 0.8 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 4.3 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.9 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 2.1 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.1 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis