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PRJEB1986: zebrafish developmental stages transcriptome

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Results for mta3

Z-value: 0.25

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Transcription factors associated with mta3

Gene Symbol Gene ID Gene Info
mta3
ENSDARG00000054903 metastasis associated 1 family, member 3
mta3
ENSDARG00000113436 metastasis associated 1 family, member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mta3dr11_v1_chr12_+_25223843_25223873-0.483.7e-02Click!

Activity profile of mta3 motif

Sorted Z-values of mta3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_43056153 1.01 ENSDART00000186377
prnpa
prion protein a
chr21_+_25187210 0.84 ENSDART00000101147
ENSDART00000167528
si:dkey-183i3.5
si:dkey-183i3.5
chr2_-_22535 0.61 ENSDART00000157877
CABZ01092282.1

chr5_-_20678300 0.47 ENSDART00000088639
wscd2
WSC domain containing 2
chr13_+_1100197 0.43 ENSDART00000139560
ppp3r1a
protein phosphatase 3, regulatory subunit B, alpha a
chr11_-_44543082 0.42 ENSDART00000099568
gpr137bb
G protein-coupled receptor 137Bb
chr3_+_16566361 0.41 ENSDART00000132869
ENSDART00000080771
slc6a16a
solute carrier family 6, member 16a
chr2_-_43168292 0.41 ENSDART00000132588
crema
cAMP responsive element modulator a
chr14_-_572742 0.40 ENSDART00000168951
fgf2
fibroblast growth factor 2
chr11_-_32723851 0.37 ENSDART00000155592
pcdh17
protocadherin 17
chr14_-_2369849 0.37 ENSDART00000180422
ENSDART00000189731
ENSDART00000111748
pcdhb
protocadherin b
chr16_-_17207754 0.37 ENSDART00000063804
wu:fj39g12
wu:fj39g12
chr7_-_6592142 0.34 ENSDART00000160137
kcnj10a
potassium inwardly-rectifying channel, subfamily J, member 10a
chr21_+_44581654 0.30 ENSDART00000187201
ENSDART00000180360
ENSDART00000191543
ENSDART00000180039
ENSDART00000186308
TMEM164
transmembrane protein 164
chr10_-_9115383 0.29 ENSDART00000139324
si:dkeyp-41f9.3
si:dkeyp-41f9.3
chr23_-_24825863 0.27 ENSDART00000112493
syt6a
synaptotagmin VIa
chr20_-_51727860 0.25 ENSDART00000147044
brox
BRO1 domain and CAAX motif containing
chr12_-_14551077 0.25 ENSDART00000188717
FO704673.1

chr16_-_280835 0.25 ENSDART00000190541
LO017917.1

chr7_+_1579510 0.25 ENSDART00000190525
supt16h
SPT16 homolog, facilitates chromatin remodeling subunit
chr5_+_45138934 0.21 ENSDART00000041412
ENSDART00000136002
smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr3_-_5228137 0.18 ENSDART00000137105
myh9b
myosin, heavy chain 9b, non-muscle
chr9_-_1434484 0.17 ENSDART00000093412
osbpl6
oxysterol binding protein-like 6
chr5_-_25123807 0.16 ENSDART00000183171
abca2
ATP-binding cassette, sub-family A (ABC1), member 2
chr20_-_33675676 0.16 ENSDART00000147168
rock2b
rho-associated, coiled-coil containing protein kinase 2b
chr5_+_45139196 0.15 ENSDART00000113738
smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_-_56095275 0.15 ENSDART00000154701
si:ch211-178n15.1
si:ch211-178n15.1
chr2_-_16359042 0.14 ENSDART00000057216
arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr19_+_41769135 0.14 ENSDART00000087096
tinagl1
tubulointerstitial nephritis antigen-like 1
chr13_+_31545812 0.12 ENSDART00000076527
ppm1aa
protein phosphatase, Mg2+/Mn2+ dependent, 1Aa
chr2_+_13069168 0.09 ENSDART00000192832
prkag2b
protein kinase, AMP-activated, gamma 2 non-catalytic subunit b
chr10_-_43928937 0.09 ENSDART00000168014
ENSDART00000086220
mctp1b
multiple C2 domains, transmembrane 1b
chr13_+_23093743 0.08 ENSDART00000148034
pik3ap1
phosphoinositide-3-kinase adaptor protein 1
chr16_+_11029762 0.08 ENSDART00000091183
erfl3
Ets2 repressor factor like 3
chr25_-_35106751 0.05 ENSDART00000180682
ENSDART00000073457
zgc:194989
zgc:194989
chr22_-_7809904 0.05 ENSDART00000182269
ENSDART00000097201
ENSDART00000138522
si:ch73-44m9.3
si:ch73-44m9.1
si:ch73-44m9.3
si:ch73-44m9.1
chr16_+_13822137 0.02 ENSDART00000163251
flcn
folliculin
chr4_-_13255700 0.01 ENSDART00000162277
ENSDART00000026593
grip1
glutamate receptor interacting protein 1
chr4_+_77971104 0.00 ENSDART00000188609
zgc:113921
zgc:113921

Network of associatons between targets according to the STRING database.

First level regulatory network of mta3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.1 0.4 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.3 GO:0036268 swimming(GO:0036268)
0.0 0.2 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 0.4 GO:0030323 respiratory tube development(GO:0030323) lung development(GO:0030324)
0.0 0.4 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis