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PRJEB1986: zebrafish developmental stages transcriptome

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Results for meis1a+meis1b

Z-value: 1.36

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Transcription factors associated with meis1a+meis1b

Gene Symbol Gene ID Gene Info
ENSDARG00000002937 Meis homeobox 1 a
ENSDARG00000012078 Meis homeobox 1 b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
meis1adr11_v1_chr1_+_51496862_51496862-0.862.2e-06Click!
meis1bdr11_v1_chr13_-_5569562_5569562-0.588.9e-03Click!

Activity profile of meis1a+meis1b motif

Sorted Z-values of meis1a+meis1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_1796426 8.10 ENSDART00000173330
low density lipoprotein receptor-related protein 1Aa
chr16_+_52512025 7.43 ENSDART00000056095
fatty acid binding protein 10a, liver basic
chr20_+_35473288 3.50 ENSDART00000047195
meprin A, alpha (PABA peptide hydrolase), tandem duplicate 1
chr19_+_40856534 3.39 ENSDART00000051950
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr25_-_4482449 3.39 ENSDART00000056278
ENSDART00000149425
solute carrier family 25 member 22a
chr11_+_25459697 3.32 ENSDART00000161481
opsin 1 (cone pigments), short-wave-sensitive 2
chr19_+_48111285 3.22 ENSDART00000169420
NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 2
chr15_+_19652807 3.19 ENSDART00000134321
ENSDART00000054426
lens intrinsic membrane protein 2.3
chr13_-_7031033 3.12 ENSDART00000193211

chr16_-_13612650 3.04 ENSDART00000080372
D site albumin promoter binding protein b
chr19_+_40856807 3.03 ENSDART00000139083
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr24_+_3307857 2.95 ENSDART00000106527
glycogenin 1b
chr1_+_14432434 2.82 ENSDART00000024328
solute carrier family 34 (type II sodium/phosphate cotransporter), member 2a
chr18_+_1703984 2.80 ENSDART00000114010
SLIT and NTRK-like family, member 3a
chr9_-_43071519 2.76 ENSDART00000109099
titin, tandem duplicate 2
chr10_-_22831611 2.73 ENSDART00000160115
period circadian clock 1a
chr20_-_7176809 2.73 ENSDART00000012247
ENSDART00000125019
24-dehydrocholesterol reductase
chr20_-_5291012 2.68 ENSDART00000122892
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 3
chr16_-_16152199 2.66 ENSDART00000012718
fatty acid binding protein 11b
chr23_-_27875140 2.63 ENSDART00000143662
ankyrin repeat domain 33Aa
chr13_+_27314795 2.53 ENSDART00000128726
eukaryotic translation elongation factor 1 alpha 1a
chr24_-_27400017 2.52 ENSDART00000145829
chemokine (C-C motif) ligand 34b, duplicate 1
chr4_-_9549693 2.46 ENSDART00000160242

chr10_-_22249444 2.39 ENSDART00000148831
fibroblast growth factor 11b
chr19_-_6988837 2.37 ENSDART00000145741
ENSDART00000167640
zinc finger protein 384 like
chr4_+_7841627 2.34 ENSDART00000037997
upper zone of growth plate and cartilage matrix associated a
chr17_+_22311413 2.33 ENSDART00000151929
solute carrier family 8 (sodium/calcium exchanger), member 1b
chr6_-_8580857 2.31 ENSDART00000138858
ENSDART00000041142
myosin, heavy chain 11a, smooth muscle
chr13_+_27073901 2.29 ENSDART00000146227
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr16_-_13613475 2.29 ENSDART00000139102
D site albumin promoter binding protein b
chr2_+_394166 2.27 ENSDART00000155733
myosin light chain kinase family, member 4a
chr14_+_22172047 2.25 ENSDART00000114750
ENSDART00000148259
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr20_-_1151265 2.24 ENSDART00000012376
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr20_-_17041025 2.22 ENSDART00000063764
si:dkey-5n18.1
chr11_+_40649412 2.22 ENSDART00000043016
ENSDART00000134560
solute carrier family 45, member 1
chr5_-_26093945 2.22 ENSDART00000010199
ENSDART00000145096
family with sequence similarity 219, member Ab
chr13_-_21701323 2.18 ENSDART00000164112
si:dkey-191g9.7
chr7_-_65492048 2.17 ENSDART00000162381
dickkopf WNT signaling pathway inhibitor 3a
chr24_-_11325849 2.16 ENSDART00000182485
myosin VIIA and Rab interacting protein
chr18_+_28564640 2.16 ENSDART00000016983
spondin 1a
chr21_-_16399778 2.13 ENSDART00000136435
unc-5 netrin receptor Da
chr10_+_25726694 2.10 ENSDART00000140308
UDP glucuronosyltransferase 5 family, polypeptide D1
chr8_-_21268303 2.09 ENSDART00000067211
G protein-coupled receptor 37 like 1b
chr16_+_11558868 2.09 ENSDART00000112497
ENSDART00000180445
zgc:198329
chr5_+_26079178 2.08 ENSDART00000145920
si:dkey-201c13.2
chr11_-_36957127 2.06 ENSDART00000168528
calcium channel, voltage-dependent, L type, alpha 1D subunit, a
chr16_+_6944311 2.05 ENSDART00000144763
ELL associated factor 1
chr12_-_31461219 2.02 ENSDART00000148954
acyl-CoA synthetase long chain family member 5
chr21_+_11468934 2.01 ENSDART00000126045
ENSDART00000129744
ENSDART00000102368
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr25_+_10458990 1.95 ENSDART00000130354
ENSDART00000044738
RIC8 guanine nucleotide exchange factor A
chr7_+_73444325 1.93 ENSDART00000123016
si:ch211-142d6.2
chr2_+_7192966 1.92 ENSDART00000142735
si:ch211-13f8.1
chr5_-_13086616 1.91 ENSDART00000051664
yippee-like 1
chr16_-_50175069 1.89 ENSDART00000192979
lens intrinsic membrane protein 2.5
chr12_+_1286642 1.89 ENSDART00000157467
phosphatidylethanolamine N-methyltransferase
chr11_-_24428237 1.87 ENSDART00000189107
ENSDART00000103752
dishevelled segment polarity protein 1b
chr16_-_18960613 1.86 ENSDART00000183197
formin homology 2 domain containing 3b
chr8_+_19621511 1.86 ENSDART00000017128
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3a
chr10_+_21576909 1.85 ENSDART00000168604
ENSDART00000166533
protocadherin 1 alpha 3
chr6_+_58280936 1.85 ENSDART00000155244
Ral GTPase activating protein, beta subunit (non-catalytic)
chr3_-_1190132 1.85 ENSDART00000149709
single-pass membrane protein with aspartate-rich tail 1a
chr25_-_17403598 1.85 ENSDART00000104216
cytochrome P450, family 2, subfamily X, polypeptide 9
chr22_-_13851297 1.83 ENSDART00000080306
S100 calcium binding protein, beta (neural)
chr5_-_18446483 1.83 ENSDART00000180027
si:dkey-215k6.1
chr17_+_31185276 1.82 ENSDART00000062887
dispatched homolog 2 (Drosophila)
chr2_-_28671139 1.81 ENSDART00000165272
ENSDART00000164657
7-dehydrocholesterol reductase
chr13_+_3819475 1.78 ENSDART00000139958
QKI, KH domain containing, RNA binding b
chr7_-_13884610 1.78 ENSDART00000006897
retinaldehyde binding protein 1a
chr21_-_28523548 1.75 ENSDART00000077910
ependymin-like 2
chr16_+_50089417 1.75 ENSDART00000153675
nuclear receptor subfamily 1, group D, member 2a
chr9_-_22822084 1.73 ENSDART00000142020
nebulin
chr2_-_38125657 1.69 ENSDART00000143433
cerebellin 12
chr20_-_5267600 1.68 ENSDART00000099258
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 4
chr4_-_5291256 1.64 ENSDART00000150864
si:ch211-214j24.9
chr15_-_39963009 1.61 ENSDART00000157388
ly6 domain containing, pigment cell
chr7_+_34227075 1.61 ENSDART00000052477
ENSDART00000173732
lactase-like a
chr18_-_21271373 1.60 ENSDART00000060001
purine nucleoside phosphorylase 6
chr22_-_33679277 1.59 ENSDART00000169948

chr8_+_19621731 1.59 ENSDART00000144667
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3a
chr6_+_48041759 1.57 ENSDART00000140086
si:dkey-92f12.2
chr21_-_44556148 1.55 ENSDART00000163955
BRCA1/BRCA2-containing complex, subunit 3
chr6_+_3280939 1.55 ENSDART00000151359
lysine (K)-specific demethylase 4A, genome duplicate a
chr8_-_49399470 1.55 ENSDART00000136395
si:ch211-194e1.7
chr8_-_45838277 1.54 ENSDART00000046064
oxoglutarate (alpha-ketoglutarate) dehydrogenase a (lipoamide)
chr10_-_7974155 1.51 ENSDART00000147368
ENSDART00000075524
oxysterol binding protein 2
chr7_-_67214972 1.51 ENSDART00000156861
switching B cell complex subunit SWAP70a
chr9_-_22821901 1.48 ENSDART00000101711
nebulin
chr19_-_9503473 1.47 ENSDART00000091615
intermediate filament family orphan 1a
chr6_-_24203980 1.46 ENSDART00000170915
si:ch73-389b16.2
chr11_-_9948487 1.46 ENSDART00000189677
ENSDART00000113171
neuroligin 1
chr9_+_29643036 1.46 ENSDART00000023210
ENSDART00000175160
tripartite motif containing 13
chr23_+_40410644 1.43 ENSDART00000056328
ELOVL fatty acid elongase 4b
chr8_+_52284075 1.39 ENSDART00000098439
ubiquitin-conjugating enzyme E2D 4 (putative)
chr5_-_21030934 1.39 ENSDART00000133461
ENSDART00000098667
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1
chr16_-_18960333 1.39 ENSDART00000143185
formin homology 2 domain containing 3b
chr3_-_1232384 1.38 ENSDART00000053892
si:ch1073-314i13.4
chr21_+_43178831 1.38 ENSDART00000151512
AF4/FMR2 family, member 4
chr13_+_36770738 1.37 ENSDART00000146696
atlastin GTPase 1
chr13_+_24584401 1.36 ENSDART00000057599
fucose mutarotase
chr14_+_2243 1.34 ENSDART00000191193
cytokine like 1
chr17_+_18117358 1.34 ENSDART00000144894
B cell CLL/lymphoma 11Ba
chr15_+_9294620 1.33 ENSDART00000133588
ENSDART00000140009
solute carrier family 37 (glucose-6-phosphate transporter), member 4a
chr22_+_15336752 1.33 ENSDART00000139070
sulfotransferase family 3, cytosolic sulfotransferase 2
chr8_-_17771755 1.32 ENSDART00000063592
protein kinase C, zeta
chr8_+_22582146 1.31 ENSDART00000157655
ENSDART00000189892

chr5_+_31480342 1.31 ENSDART00000098197
si:dkey-220k22.1
chr24_+_4373033 1.29 ENSDART00000133360
cyclin Y
chr23_+_14432323 1.27 ENSDART00000178553

chr17_-_50331351 1.26 ENSDART00000149294
otoferlin b
chr15_-_29598444 1.26 ENSDART00000154847
si:ch211-207n23.2
chr22_+_5682635 1.25 ENSDART00000140680
ENSDART00000131308
deoxyribonuclease 1 like 4, tandem duplicate 2
chr24_-_17047918 1.24 ENSDART00000020204
methionine sulfoxide reductase B2
chr13_-_37545487 1.23 ENSDART00000131269
synaptotagmin XVI
chr10_+_41765944 1.22 ENSDART00000171484
ring finger protein 34b
chr18_+_507835 1.21 ENSDART00000189701
neural precursor cell expressed, developmentally down-regulated 4a
chr19_-_40826024 1.20 ENSDART00000131471
calcitonin receptor
chr3_-_60401826 1.19 ENSDART00000144030
ENSDART00000160821
si:ch211-214b16.4
chr9_+_27411502 1.18 ENSDART00000143994
si:dkey-193n17.9
chr24_+_27268001 1.18 ENSDART00000122639
vasoactive intestinal peptide receptor 2
chr25_-_35542739 1.18 ENSDART00000097651
si:ch211-87j1.4
chr7_+_6990510 1.17 ENSDART00000138948
copper chaperone for superoxide dismutase
chr2_-_50372467 1.17 ENSDART00000108900
contactin associated protein like 2b
chr17_-_43533095 1.17 ENSDART00000125162
si:dkey-21a6.5
chr5_-_43682930 1.17 ENSDART00000075017
si:dkey-40c11.1
chr12_+_2993523 1.16 ENSDART00000082297
leucine rich repeat containing 45
chr23_+_23183449 1.16 ENSDART00000132296
kelch-like family member 17
chr4_-_5302866 1.16 ENSDART00000138590
si:ch211-214j24.9
chr7_+_27898091 1.15 ENSDART00000186451
ENSDART00000173510
tubby bipartite transcription factor
chr3_+_29082267 1.14 ENSDART00000145615
calcium channel, voltage-dependent, T type, alpha 1I subunit
chr25_+_5604512 1.14 ENSDART00000042781
plexin b2b
chr24_-_20320480 1.12 ENSDART00000137366
mitogen-activated protein kinase kinase kinase 20
chr13_-_29505604 1.12 ENSDART00000110005
cadherin-related family member 1a
chr10_-_26512742 1.12 ENSDART00000135951
si:dkey-5g14.1
chr15_-_29598679 1.11 ENSDART00000155153
si:ch211-207n23.2
chr1_-_5455498 1.11 ENSDART00000040368
ENSDART00000114035
motor neuron and pancreas homeobox 2b
chr10_+_21722892 1.10 ENSDART00000162855
protocadherin 1 gamma 13
chr8_+_14792830 1.10 ENSDART00000139972
calcium channel, voltage-dependent, R type, alpha 1E subunit a
chr1_+_57331813 1.10 ENSDART00000152440
ENSDART00000062841
epsin 3b
chr23_+_20689255 1.09 ENSDART00000182420
ubiquitin specific peptidase 21
chr23_+_5470967 1.09 ENSDART00000110522
ENSDART00000149050
tubby like protein 1a
chr13_-_20519001 1.09 ENSDART00000168955
gdnf family receptor alpha 1a
chr20_+_23173710 1.09 ENSDART00000074172
sarcoglycan, beta (dystrophin-associated glycoprotein)
chr10_+_22782522 1.08 ENSDART00000079498
ENSDART00000145558
si:ch211-237l4.6
chr9_-_12575776 1.08 ENSDART00000128931
ENSDART00000182695
insulin-like growth factor 2 mRNA binding protein 2a
chr16_-_38001040 1.07 ENSDART00000133861
ENSDART00000138711
ENSDART00000143846
ENSDART00000146564
si:ch211-198c19.3
chr2_-_33676494 1.07 ENSDART00000141192
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr3_+_12861158 1.06 ENSDART00000171237
potassium inwardly-rectifying channel, subfamily J, member 2b
chr15_+_42933236 1.06 ENSDART00000167763
solute carrier family 8 (sodium/calcium exchanger), member 2b
chr23_-_11128601 1.06 ENSDART00000131232
contactin 3a, tandem duplicate 2
chr4_-_5302162 1.05 ENSDART00000177099
si:ch211-214j24.9
chr17_-_29771639 1.05 ENSDART00000086201
Usher syndrome 2A (autosomal recessive, mild)
chr18_-_7810214 1.04 ENSDART00000139505
ENSDART00000139188
SH3 and multiple ankyrin repeat domains 3a
chr5_-_67661102 1.04 ENSDART00000013605
zinc finger and BTB domain containing 20
chr6_+_58915889 1.02 ENSDART00000083628
DNA-damage-inducible transcript 3
chr23_-_36724575 1.02 ENSDART00000159560
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr8_-_31384607 1.01 ENSDART00000164134
ENSDART00000024872
cAMP responsive element binding protein 3-like 3 like
chr4_-_17629444 1.00 ENSDART00000108814
nuclear receptor interacting protein 2
chr9_-_12575569 0.99 ENSDART00000102419
insulin-like growth factor 2 mRNA binding protein 2a
chr3_-_30609659 0.99 ENSDART00000182516
ENSDART00000187047
ENSDART00000110597
synaptotagmin III
chr25_+_32525131 0.99 ENSDART00000156145
S-phase cyclin A-associated protein in the ER
chr20_-_8094718 0.98 ENSDART00000122902
si:ch211-232i5.3
chr15_-_20956384 0.98 ENSDART00000135770
tubulin folding cofactor E-like a
chr2_+_33335911 0.98 ENSDART00000126135
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr2_+_30147504 0.97 ENSDART00000190947
potassium voltage-gated channel, Shab-related subfamily, member 2
chr10_+_4806323 0.96 ENSDART00000161789
paralemmin 2
chr13_+_15182149 0.96 ENSDART00000193644
ENSDART00000134421
ENSDART00000086281
mitochondrial antiviral signaling protein
chr13_-_29505946 0.95 ENSDART00000026679
cadherin-related family member 1a
chr19_+_7567763 0.94 ENSDART00000140411
S100 calcium binding protein A11
chr10_-_3295197 0.92 ENSDART00000109131
slc25a1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1b
chr2_-_18830722 0.92 ENSDART00000165330
ENSDART00000165698
pre-B-cell leukemia homeobox 1a
chr6_+_39493864 0.90 ENSDART00000086263
methyltransferase like 7A
chr15_-_4415917 0.89 ENSDART00000062874
ATPase Na+/K+ transporting subunit beta 3b
chr6_+_54154807 0.89 ENSDART00000061735
nudix (nucleoside diphosphate linked moiety X)-type motif 3b
chr2_+_6127593 0.89 ENSDART00000184007
fizzy/cell division cycle 20 related 1b
chr21_-_19006631 0.88 ENSDART00000080269
ENSDART00000191682
phosphoglycerate mutase 2 (muscle)
chr23_-_29667544 0.87 ENSDART00000059339
calsyntenin 1
chr8_-_16464453 0.87 ENSDART00000098691
ring finger protein 11b
chr15_+_24588963 0.86 ENSDART00000155075
zgc:198241
chr16_-_8132742 0.86 ENSDART00000104323
SNF related kinase a
chr2_-_51719439 0.85 ENSDART00000170385
transglutaminase 1 like 1
chr2_+_11670270 0.85 ENSDART00000100524
finTRIM family, member 1
chr23_-_764135 0.84 ENSDART00000010248
ENSDART00000183978
microphthalmia-associated transcription factor b
chr22_+_35275468 0.84 ENSDART00000189516
ENSDART00000181572
ENSDART00000165353
ENSDART00000185352
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
chr24_+_39656834 0.84 ENSDART00000133942
ENSDART00000148089
ENSDART00000145075
STIP1 homology and U-Box containing protein 1
chr13_-_48161568 0.83 ENSDART00000109469
ENSDART00000188052
ENSDART00000193446
ENSDART00000189509
ENSDART00000184810
golgin A4
chr24_+_10039165 0.83 ENSDART00000144186
POU class 6 homeobox 2
chr4_-_18954001 0.83 ENSDART00000144814
si:dkey-31f5.8
chr21_+_37357578 0.83 ENSDART00000143621
nuclear receptor binding SET domain protein 1b
chr10_-_39011514 0.83 ENSDART00000075123
Purkinje cell protein 4a
chr11_+_41540862 0.82 ENSDART00000173210
potassium voltage-gated channel, shaker-related subfamily, beta member 2 a
chr25_-_4733221 0.82 ENSDART00000172689
dopamine receptor D4a
chr17_+_18117976 0.82 ENSDART00000123745
B cell CLL/lymphoma 11Ba
chr11_-_34480822 0.81 ENSDART00000129029
xyloside xylosyltransferase 1
chr24_-_20808283 0.80 ENSDART00000143759
vasoactive intestinal peptide receptor 1b
chr5_-_52569014 0.80 ENSDART00000165616
MAM domain containing 2a
chr25_+_336503 0.79 ENSDART00000160395

chr20_-_5328637 0.79 ENSDART00000075974
isthmin 2b
chr17_+_12138715 0.79 ENSDART00000112888
zgc:174379
chr16_+_30002605 0.79 ENSDART00000160555
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E
chr21_+_5888641 0.79 ENSDART00000091331
proline dehydrogenase (oxidase) 1a

Network of associatons between targets according to the STRING database.

First level regulatory network of meis1a+meis1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:2000191 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.6 2.2 GO:0070317 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.5 3.2 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.5 1.6 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.5 1.5 GO:0090219 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.5 2.8 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.4 4.9 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.3 3.4 GO:0015800 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.3 1.2 GO:0030091 protein repair(GO:0030091)
0.3 0.3 GO:0001659 temperature homeostasis(GO:0001659)
0.3 1.9 GO:0090178 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.3 1.3 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.2 1.0 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.2 1.9 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.2 1.2 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.2 0.7 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.2 0.9 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.2 3.4 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.2 1.4 GO:0006004 fucose metabolic process(GO:0006004)
0.2 0.9 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 3.7 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.2 3.2 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.2 0.8 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.2 2.1 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.2 1.0 GO:0098586 cytoplasmic pattern recognition receptor signaling pathway in response to virus(GO:0039528) cellular response to virus(GO:0098586)
0.2 3.4 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.2 2.6 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.2 2.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 0.9 GO:1901910 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.2 1.2 GO:2001271 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2 1.7 GO:1990748 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.2 2.8 GO:0048769 sarcomerogenesis(GO:0048769)
0.2 3.3 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.2 1.2 GO:0031106 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.2 0.8 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.2 2.3 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.1 1.0 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 1.0 GO:0098815 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 0.9 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 1.6 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.1 0.8 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 2.1 GO:0014812 muscle cell migration(GO:0014812)
0.1 1.5 GO:0097105 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 2.7 GO:0043153 response to hydrogen peroxide(GO:0042542) entrainment of circadian clock by photoperiod(GO:0043153)
0.1 0.8 GO:0016559 peroxisome fission(GO:0016559)
0.1 2.0 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.8 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.3 GO:0007414 axonal defasciculation(GO:0007414)
0.1 1.8 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.3 GO:0045299 otolith mineralization(GO:0045299)
0.1 0.3 GO:0030521 androgen receptor signaling pathway(GO:0030521) embryonic digestive tract morphogenesis(GO:0048557) regulation of androgen receptor signaling pathway(GO:0060765)
0.1 1.3 GO:0090049 regulation of cell migration involved in sprouting angiogenesis(GO:0090049)
0.1 0.5 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 0.4 GO:0090148 membrane fission(GO:0090148)
0.1 0.5 GO:0006788 heme oxidation(GO:0006788)
0.1 1.0 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 2.3 GO:0030856 regulation of epithelial cell differentiation(GO:0030856)
0.1 0.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 3.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 1.8 GO:0042446 hormone biosynthetic process(GO:0042446)
0.1 0.8 GO:0098900 regulation of action potential(GO:0098900)
0.1 0.4 GO:1901490 protein kinase D signaling(GO:0089700) regulation of lymphangiogenesis(GO:1901490)
0.1 0.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 1.5 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 1.4 GO:0098508 endothelial to hematopoietic transition(GO:0098508)
0.1 2.4 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.1 1.8 GO:0007634 optokinetic behavior(GO:0007634)
0.1 0.3 GO:0030852 regulation of granulocyte differentiation(GO:0030852) regulation of neutrophil differentiation(GO:0045658)
0.1 2.9 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 0.2 GO:2000257 regulation of protein activation cascade(GO:2000257)
0.1 1.8 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 0.3 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 0.6 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.4 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.1 1.7 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.1 0.5 GO:0042438 melanin biosynthetic process(GO:0042438)
0.1 1.0 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 0.5 GO:0045445 myoblast differentiation(GO:0045445)
0.1 2.1 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 0.5 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.4 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 1.9 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.5 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 2.2 GO:0061512 protein localization to cilium(GO:0061512)
0.0 1.1 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 1.3 GO:0051923 sulfation(GO:0051923)
0.0 0.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 6.1 GO:1901342 regulation of vasculature development(GO:1901342)
0.0 1.6 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 1.2 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 1.4 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 2.8 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.5 GO:0046473 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 1.8 GO:0035195 gene silencing by miRNA(GO:0035195)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:2001286 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.5 GO:0099565 chemical synaptic transmission, postsynaptic(GO:0099565)
0.0 0.8 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.6 GO:0055078 sodium ion homeostasis(GO:0055078)
0.0 0.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.9 GO:0007520 myoblast fusion(GO:0007520)
0.0 1.7 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.4 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 1.0 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.3 GO:0000266 mitochondrial fission(GO:0000266)
0.0 1.4 GO:0007623 circadian rhythm(GO:0007623)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.7 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 3.0 GO:0008202 steroid metabolic process(GO:0008202)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.4 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.7 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 0.3 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.4 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.7 GO:0021986 habenula development(GO:0021986)
0.0 0.8 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.7 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 1.8 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.1 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 0.2 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.4 GO:1902866 regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866)
0.0 4.0 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.7 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 4.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.1 GO:0097676 histone H3-K4 trimethylation(GO:0080182) histone H3-K36 dimethylation(GO:0097676)
0.0 2.6 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.8 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 1.1 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 1.3 GO:0006414 translational elongation(GO:0006414)
0.0 1.4 GO:0051028 mRNA transport(GO:0051028)
0.0 0.2 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.5 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.5 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 1.0 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 1.1 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.8 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.2 GO:0022011 myelination in peripheral nervous system(GO:0022011)
0.0 0.2 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.3 GO:0000959 mitochondrial RNA metabolic process(GO:0000959)
0.0 0.5 GO:0007416 synapse assembly(GO:0007416)
0.0 0.9 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.7 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.8 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.4 GO:0032526 response to retinoic acid(GO:0032526)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.4 GO:0032783 ELL-EAF complex(GO:0032783)
0.4 6.4 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.2 1.6 GO:0070552 BRISC complex(GO:0070552)
0.2 0.6 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.2 1.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 2.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 0.8 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 1.2 GO:0033010 paranodal junction(GO:0033010)
0.1 1.8 GO:1990246 uniplex complex(GO:1990246)
0.1 0.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 0.5 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.3 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.1 1.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.0 GO:0045240 dihydrolipoyl dehydrogenase complex(GO:0045240) oxoglutarate dehydrogenase complex(GO:0045252)
0.1 2.1 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.8 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.1 0.7 GO:0071914 prominosome(GO:0071914)
0.1 1.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 3.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 1.4 GO:0005903 brush border(GO:0005903)
0.1 0.8 GO:0098888 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 0.8 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 2.2 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 0.4 GO:0016589 NURF complex(GO:0016589)
0.1 0.7 GO:0061617 MICOS complex(GO:0061617)
0.1 2.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 1.0 GO:0030057 desmosome(GO:0030057)
0.1 1.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 1.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 4.5 GO:0042383 sarcolemma(GO:0042383)
0.0 2.8 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 3.4 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.4 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 4.1 GO:0030018 Z disc(GO:0030018)
0.0 4.1 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891) calcium channel complex(GO:0034704)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.4 GO:0099572 postsynaptic specialization(GO:0099572)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 2.8 GO:0000786 nucleosome(GO:0000786)
0.0 1.1 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 1.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.6 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.7 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 2.9 GO:0016459 myosin complex(GO:0016459)
0.0 2.3 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.6 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 2.9 GO:0005770 late endosome(GO:0005770)
0.0 0.4 GO:0032420 stereocilium(GO:0032420)
0.0 0.5 GO:0000795 synaptonemal complex(GO:0000795)
0.0 2.5 GO:0060076 excitatory synapse(GO:0060076)
0.0 1.1 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 7.4 GO:0032052 bile acid binding(GO:0032052)
0.9 5.1 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.5 2.8 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.5 1.8 GO:0044548 S100 protein binding(GO:0044548)
0.5 1.4 GO:0042806 fucose binding(GO:0042806)
0.4 2.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.4 2.2 GO:0039706 co-receptor binding(GO:0039706)
0.4 1.2 GO:0097643 amylin receptor activity(GO:0097643)
0.3 3.4 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.3 2.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.3 2.0 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.3 1.2 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.3 6.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.3 3.4 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.3 2.2 GO:0008515 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.3 3.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.3 2.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.3 2.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.2 0.7 GO:0009041 uridylate kinase activity(GO:0009041)
0.2 1.7 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 2.1 GO:0005042 netrin receptor activity(GO:0005042)
0.2 0.8 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.2 2.0 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.2 0.9 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.2 1.6 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.2 0.9 GO:1990757 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.2 0.9 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.2 4.6 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.2 2.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 2.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 1.0 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 1.6 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 1.8 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 1.6 GO:0043495 protein anchor(GO:0043495)
0.1 3.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 2.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 1.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.7 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 1.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.3 GO:0004776 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.1 1.9 GO:0005080 protein kinase C binding(GO:0005080)
0.1 1.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 2.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 2.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 2.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.5 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 2.2 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.6 GO:0070122 isopeptidase activity(GO:0070122)
0.1 1.0 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 1.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.6 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.2 GO:0098808 mRNA cap binding(GO:0098808)
0.1 3.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.4 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 2.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 1.8 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 0.4 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.6 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 1.3 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 5.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.5 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.7 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 1.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.8 GO:0051879 Hsp70 protein binding(GO:0030544) Hsp90 protein binding(GO:0051879)
0.1 0.9 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 1.5 GO:0008378 galactosyltransferase activity(GO:0008378)
0.1 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 1.8 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 0.7 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.9 GO:0001671 ATPase activator activity(GO:0001671)
0.0 2.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.4 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 2.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 2.2 GO:0017022 myosin binding(GO:0017022)
0.0 1.9 GO:0005109 frizzled binding(GO:0005109)
0.0 2.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.3 GO:0070888 E-box binding(GO:0070888)
0.0 0.4 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.5 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 1.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 1.3 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 1.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 10.0 GO:0051015 actin filament binding(GO:0051015)
0.0 0.3 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 3.2 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.0 1.8 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.5 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 1.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.8 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.9 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 3.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 2.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.7 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 1.1 GO:0005507 copper ion binding(GO:0005507)
0.0 0.5 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.4 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.3 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.6 GO:0044325 ion channel binding(GO:0044325)
0.0 1.3 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.8 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.7 GO:0030276 clathrin binding(GO:0030276)
0.0 0.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 2.5 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 10.1 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.9 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 1.8 PID RAS PATHWAY Regulation of Ras family activation
0.1 0.6 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 0.6 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.4 PID IGF1 PATHWAY IGF1 pathway
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 2.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.4 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.4 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.3 1.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.3 2.0 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2 5.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 1.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 4.5 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 1.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.9 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 1.6 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 3.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.2 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 0.8 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.1 0.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.4 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.5 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.3 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.7 REACTOME UNFOLDED PROTEIN RESPONSE Genes involved in Unfolded Protein Response
0.0 0.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation