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PRJEB1986: zebrafish developmental stages transcriptome

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Results for mef2d

Z-value: 1.95

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Transcription factors associated with mef2d

Gene Symbol Gene ID Gene Info
ENSDARG00000040237 myocyte enhancer factor 2d

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mef2ddr11_v1_chr16_-_29164379_29164379-0.894.3e-07Click!

Activity profile of mef2d motif

Sorted Z-values of mef2d motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_61205711 13.63 ENSDART00000055062
parvalbumin 1
chr24_-_24038800 9.03 ENSDART00000080549
lysozyme
chr8_-_11112058 8.62 ENSDART00000042755
adenosine monophosphate deaminase 1 (isoform M)
chr25_+_29160102 8.42 ENSDART00000162854
pyruvate kinase M1/2b
chr10_+_26800213 7.33 ENSDART00000078996
arrestin 3a, retinal (X-arrestin)
chr12_-_17712393 7.04 ENSDART00000143534
ENSDART00000010144
parvalbumin 2
chr1_+_7546259 6.97 ENSDART00000015732
myosin, light polypeptide 3, skeletal muscle
chr12_+_16440708 6.65 ENSDART00000113810
ankyrin repeat domain 1b (cardiac muscle)
chr12_-_17707449 6.60 ENSDART00000142427
ENSDART00000034914
parvalbumin 3
chr5_+_51597677 6.34 ENSDART00000048210
ENSDART00000184797
creatine kinase, mitochondrial 2b (sarcomeric)
chr15_+_19652807 5.76 ENSDART00000134321
ENSDART00000054426
lens intrinsic membrane protein 2.3
chr5_+_45677781 5.47 ENSDART00000163120
ENSDART00000126537
group-specific component (vitamin D binding protein)
chr3_+_59051503 5.42 ENSDART00000160767
rasd family member 4
chr5_+_36932718 5.20 ENSDART00000037879
cone-rod homeobox
chr16_-_43356018 5.05 ENSDART00000181683

chr2_+_16536453 4.84 ENSDART00000100287
G protein-coupled receptor kinase 7a
chr8_+_22930627 4.56 ENSDART00000187860
synaptophysin a
chr7_-_7420301 4.55 ENSDART00000102620
SIX homeobox 7
chr20_-_26001288 4.55 ENSDART00000136518
ENSDART00000063177
calpain 3b
chr1_+_19332837 4.48 ENSDART00000078594
tyrosinase-related protein 1b
chr14_+_32838110 4.48 ENSDART00000158077
arrestin 3b, retinal (X-arrestin)
chr17_-_12336987 4.36 ENSDART00000172001
synaptosomal-associated protein, 25b
chr4_-_9592402 4.34 ENSDART00000114060
cerebral dopamine neurotrophic factor
chr15_+_47903864 4.33 ENSDART00000063835
orthodenticle homolog 5
chr7_+_14291323 4.31 ENSDART00000053521
Rh family, C glycoprotein a
chr5_-_72125551 4.24 ENSDART00000149412
SET and MYND domain containing 1a
chr11_+_11201096 4.21 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myomesin 2a
chr9_+_31795343 4.16 ENSDART00000139584
integrin, beta-like 1
chr21_+_12010505 4.16 ENSDART00000123522
aquaporin 7
chr10_-_22845485 4.07 ENSDART00000079454
vesicle-associated membrane protein 2
chr21_-_22737228 4.03 ENSDART00000151366
F-box protein 40, tandem duplicate 2
chr6_-_35472923 3.96 ENSDART00000185907
regulator of G protein signaling 8
chr21_-_12272543 3.95 ENSDART00000081510
ENSDART00000151297
CUGBP, Elav-like family member 4
chr7_-_13381129 3.94 ENSDART00000164326
si:ch73-119p20.1
chr14_-_11430566 3.88 ENSDART00000137154
ENSDART00000091158
immunoresponsive gene 1, like
chr6_-_40697585 3.86 ENSDART00000113196
si:ch211-157b11.14
chr3_-_31079186 3.85 ENSDART00000145636
ENSDART00000140569
elongin B
elongin B
chr21_-_25685739 3.84 ENSDART00000129619
ENSDART00000101205
phosphorylase kinase, gamma 1b (muscle)
chr7_+_31879986 3.78 ENSDART00000138491
myosin binding protein C, cardiac
chr17_-_45552602 3.71 ENSDART00000154844
ENSDART00000034432
sushi domain containing 4
chr14_+_45675306 3.69 ENSDART00000105461
retinal outer segment membrane protein 1b
chr24_-_4765740 3.68 ENSDART00000121576
carboxypeptidase B1 (tissue)
chr14_+_11430796 3.66 ENSDART00000165275
si:ch211-153b23.3
chr23_-_38497705 3.65 ENSDART00000109493
teashirt zinc finger homeobox 2
chr25_+_31222069 3.65 ENSDART00000159373
troponin I type 2a (skeletal, fast), tandem duplicate 1
chr10_+_29698467 3.55 ENSDART00000163402
discs, large homolog 2 (Drosophila)
chr10_-_23358357 3.53 ENSDART00000135475
cell adhesion molecule 2a
chr22_-_906757 3.51 ENSDART00000193182

chr22_-_38137908 3.40 ENSDART00000104528
transmembrane 4 L six family member 4
chr16_-_32975951 3.29 ENSDART00000101969
ENSDART00000175149
malic enzyme 1, NADP(+)-dependent, cytosolic
chr19_+_5072918 3.27 ENSDART00000037126
enolase 2
chr22_+_17205608 3.27 ENSDART00000181267
RAB3B, member RAS oncogene family
chr17_-_15611744 3.26 ENSDART00000010496
four and a half LIM domains 5
chr15_+_40008370 3.23 ENSDART00000063783
integral membrane protein 2Ca
chr7_+_31879649 3.23 ENSDART00000099789
myosin binding protein C, cardiac
chr2_-_43168292 3.20 ENSDART00000132588
cAMP responsive element modulator a
chr21_-_131236 3.13 ENSDART00000160005
si:ch1073-398f15.1
chr12_-_19007834 3.12 ENSDART00000153248
chondroadherin-like b
chr25_+_14092871 3.03 ENSDART00000067239
guanylate cyclase activator 1g
chr19_+_15571290 3.03 ENSDART00000131134
forkhead box O6 b
chr25_+_16945348 3.01 ENSDART00000016591
fibroblast growth factor 6a
chr14_+_32837914 2.97 ENSDART00000158888
arrestin 3b, retinal (X-arrestin)
chr1_+_8601935 2.96 ENSDART00000152367
si:ch211-160d14.6
chr4_+_19534833 2.93 ENSDART00000140028
leucine rich repeat containing 4.1
chr10_+_37145007 2.90 ENSDART00000131777
CUE domain containing 1a
chr12_-_26064105 2.89 ENSDART00000168825
LIM domain binding 3b
chr23_+_6077503 2.85 ENSDART00000081714
ENSDART00000139834
myosin binding protein Ha
chr23_-_32157865 2.84 ENSDART00000000876
nuclear receptor subfamily 4, group A, member 1
chr7_-_28148310 2.81 ENSDART00000044208
LIM domain only 1
chr10_-_24371312 2.78 ENSDART00000149362
phosphatidylinositol transfer protein, alpha b
chr22_-_29204960 2.73 ENSDART00000131386
parvalbumin 7
chr5_-_33215261 2.71 ENSDART00000097935
ENSDART00000134777
si:dkey-226m8.10
chr5_+_66132394 2.68 ENSDART00000073892
zgc:114041
chr15_-_23645810 2.62 ENSDART00000168845
creatine kinase, muscle b
chr25_-_29363934 2.62 ENSDART00000166889
neuroplastin a
chr20_+_41549200 2.60 ENSDART00000135715
family with sequence similarity 184, member A
chr12_-_4028079 2.56 ENSDART00000128676
si:ch211-180a12.2
chr11_+_11200550 2.54 ENSDART00000181339
ENSDART00000187116
myomesin 2a
chr19_-_31035155 2.53 ENSDART00000161882
basic leucine zipper and W2 domains 2
chr4_-_4780667 2.51 ENSDART00000133973
si:ch211-258f14.2
chr3_+_28953274 2.49 ENSDART00000133528
ENSDART00000103602
lectin, galactoside-binding, soluble, 2a
chr14_-_30366196 2.47 ENSDART00000007022
platelet-derived growth factor receptor-like
chr8_+_44703864 2.43 ENSDART00000016225
steroidogenic acute regulatory protein
chr24_+_34089977 2.41 ENSDART00000157466
ankyrin repeat and SOCS box containing 10
chr13_-_22843562 2.40 ENSDART00000142738
phenazine biosynthesis like protein domain containing
chr23_+_22658700 2.38 ENSDART00000192248
enolase 1a, (alpha)
chr19_-_31035325 2.36 ENSDART00000147504
basic leucine zipper and W2 domains 2
chr25_+_19954576 2.35 ENSDART00000149335
potassium voltage-gated channel, shaker-related subfamily, member 1a
chr6_-_40722480 2.32 ENSDART00000188187
kelch repeat and BTB (POZ) domain containing 12
chr3_+_23092762 2.29 ENSDART00000142884
ENSDART00000024136
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a
chr7_-_66864756 2.27 ENSDART00000184462
ENSDART00000189424
adenosine monophosphate deaminase 3a
chr21_-_22730832 2.26 ENSDART00000101797
F-box protein 40, tandem duplicate 1
chr13_+_22249636 2.23 ENSDART00000108472
ENSDART00000173123
synaptopodin 2-like a
chr21_-_32487061 2.21 ENSDART00000114359
ENSDART00000131591
ENSDART00000131477
si:dkeyp-72g9.4
chr20_-_39271844 2.18 ENSDART00000192708
clusterin
chr21_-_22828593 2.18 ENSDART00000150993
angiopoietin-like 5
chr24_+_34085940 2.14 ENSDART00000171189
ankyrin repeat and SOCS box containing 10
chr23_-_21515182 2.13 ENSDART00000142000
ring finger protein 207b
chr5_-_51819027 2.05 ENSDART00000164267
homer scaffolding protein 1b
chr9_-_23990416 2.02 ENSDART00000113176
collagen, type VI, alpha 3
chr25_-_4482449 2.02 ENSDART00000056278
ENSDART00000149425
solute carrier family 25 member 22a
chr13_-_32635859 2.01 ENSDART00000146249
ENSDART00000145395
ENSDART00000148040
ENSDART00000100650
matrilin 3b
chr17_+_30442518 1.97 ENSDART00000155264
lipin 1
chr8_-_38616712 1.95 ENSDART00000141827
si:ch211-198d23.1
chr16_+_29663809 1.87 ENSDART00000191336
tropomodulin 4 (muscle)
chr8_+_52637507 1.85 ENSDART00000163830
si:dkey-90l8.3
chr2_+_9552456 1.85 ENSDART00000056896
DnaJ (Hsp40) homolog, subfamily B, member 4
chr18_+_19974289 1.85 ENSDART00000090334
ENSDART00000192982
SKI family transcriptional corepressor 1b
chr25_+_31264155 1.82 ENSDART00000012256
troponin I type 2a (skeletal, fast), tandem duplicate 3
chr23_+_20110086 1.81 ENSDART00000054664
troponin C type 1b (slow)
chr19_-_25519612 1.80 ENSDART00000133150
si:dkey-202e17.1
chr16_+_34523515 1.78 ENSDART00000041007
stathmin 1b
chr22_-_31059670 1.76 ENSDART00000022445
cullin-associated and neddylation-dissociated 2 (putative)
chr7_+_46004893 1.72 ENSDART00000183798
si:ch211-260e23.9
chr25_-_13381854 1.72 ENSDART00000164621
ENSDART00000169129
NDRG family member 4
chr22_+_20195280 1.72 ENSDART00000088603
ENSDART00000135692
si:dkey-110c1.7
chr7_-_48263516 1.70 ENSDART00000006619
ENSDART00000142370
ENSDART00000148273
ENSDART00000147968
RNA binding protein with multiple splicing 2b
chr8_+_21146262 1.69 ENSDART00000045684
porcupine O-acyltransferase
chr17_-_43558494 1.66 ENSDART00000103830
5'-nucleotidase, cytosolic IAb
chr19_-_7321221 1.66 ENSDART00000092375
oxidation resistance 1b
chr10_+_40836378 1.65 ENSDART00000085792
tripartite motif containing 69
chr20_+_16881883 1.63 ENSDART00000130107
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a
chr11_-_29685853 1.63 ENSDART00000128468
nuclear receptor subfamily 0, group B, member 1
chr3_+_14339728 1.62 ENSDART00000184127
phospholipid phosphatase related 2a
chr25_+_3677650 1.62 ENSDART00000154348
prion protein, related sequence 3
chr7_+_25059845 1.62 ENSDART00000077215
protein phosphatase 2, regulatory subunit B', beta
chr5_-_10946232 1.61 ENSDART00000163139
ENSDART00000031265
reticulon 4 receptor
chr7_-_33961551 1.59 ENSDART00000100104
SKI family transcriptional corepressor 1a
chr7_-_69298271 1.58 ENSDART00000122935
PH domain and leucine rich repeat protein phosphatase 2
chr4_+_11375894 1.55 ENSDART00000190471
ENSDART00000143963
piccolo presynaptic cytomatrix protein a
chr21_+_11684830 1.54 ENSDART00000147473
proprotein convertase subtilisin/kexin type 1
chr21_+_28445052 1.54 ENSDART00000077871
phosphorylase, glycogen, muscle A
chr10_-_39153959 1.53 ENSDART00000150193
ENSDART00000111362
solute carrier family 37 (glucose-6-phosphate transporter), member 4b
chr14_-_32405387 1.52 ENSDART00000184647
fibroblast growth factor 13a
chr2_+_2737422 1.51 ENSDART00000032459
aquaporin 1a (Colton blood group), tandem duplicate 1
chr9_-_52814204 1.50 ENSDART00000140771
ENSDART00000007401
si:ch211-45c16.2
chr10_+_15255012 1.50 ENSDART00000023766
very low density lipoprotein receptor
chr10_-_29816467 1.50 ENSDART00000055913
histone 2, H2, like
chr16_+_21738194 1.50 ENSDART00000163688
Danio rerio si:ch211-154o6.4 (si:ch211-154o6.4), mRNA.
chr6_-_15101477 1.48 ENSDART00000187713
ENSDART00000124132
four and a half LIM domains 2b
chr10_+_15255198 1.47 ENSDART00000139047
ENSDART00000172107
ENSDART00000183413
ENSDART00000185314
very low density lipoprotein receptor
chr4_-_4780510 1.46 ENSDART00000109609
si:ch211-258f14.2
chr8_+_44420108 1.46 ENSDART00000075381

chr9_-_12424791 1.45 ENSDART00000135447
ENSDART00000088199
zgc:162707
chr1_-_38815361 1.45 ENSDART00000148790
ENSDART00000148572
ENSDART00000149080
ankyrin repeat and SOCS box containing 5b
chr25_-_24074500 1.44 ENSDART00000040410
tyrosine hydroxylase
chr1_-_38813679 1.44 ENSDART00000148917
ankyrin repeat and SOCS box containing 5b
chr25_+_27923846 1.44 ENSDART00000047007
solute carrier family 13 member 1
chr13_+_25853757 1.41 ENSDART00000132521
B cell CLL/lymphoma 11Aa
chr7_+_27691647 1.40 ENSDART00000079091
cytochrome P450, family 2, subfamily R, polypeptide 1
chr21_+_11685009 1.37 ENSDART00000014668
proprotein convertase subtilisin/kexin type 1
chr11_-_31039533 1.37 ENSDART00000127355
immediate early response 2b
chr23_+_28648864 1.37 ENSDART00000189096
L1 cell adhesion molecule, paralog a
chr7_-_42206720 1.37 ENSDART00000110907
integrin alpha FG-GAP repeat containing 1
chr3_-_14103551 1.34 ENSDART00000127604
nuclear factor, interleukin 3 regulated, member 6
chr23_+_20687340 1.33 ENSDART00000143503
ubiquitin specific peptidase 21
chr1_+_36674584 1.33 ENSDART00000186772
ENSDART00000192274
endothelin receptor type Aa
chr14_-_7245971 1.32 ENSDART00000108796
storkhead box 2b
chr12_+_29173523 1.31 ENSDART00000153212
adhesion G protein-coupled receptor A1a
chr17_-_722218 1.30 ENSDART00000160385
solute carrier family 25 member 29
chr4_+_77060861 1.29 ENSDART00000174271
ENSDART00000174393
ENSDART00000150450
si:dkey-240n22.8
chr10_-_8033468 1.29 ENSDART00000140476
ATPase H+ transporting V0 subunit a2a
chr10_+_22724059 1.28 ENSDART00000136123
lysine (K)-specific demethylase 6B, b
chr1_+_44992207 1.28 ENSDART00000172357
transmembrane protein 132A
chr13_-_11536951 1.27 ENSDART00000018155
adenylosuccinate synthase
chr8_-_32497815 1.26 ENSDART00000122359
si:dkey-164f24.2
chr21_-_5799122 1.25 ENSDART00000129351
ENSDART00000151202
cyclin I
chr11_+_42474694 1.24 ENSDART00000056048
ENSDART00000184710
si:ch1073-165f9.2
chr6_-_19351495 1.22 ENSDART00000164287
growth factor receptor-bound protein 2a
chr3_-_49504023 1.22 ENSDART00000168108
protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a
chr24_-_20444844 1.21 ENSDART00000048940
villin-like
chr10_-_39154594 1.20 ENSDART00000148825
solute carrier family 37 (glucose-6-phosphate transporter), member 4b
chr17_-_50234004 1.20 ENSDART00000058706
v-fos FBJ murine osteosarcoma viral oncogene homolog Aa
chr7_+_6969909 1.20 ENSDART00000189886
actinin alpha 3b
chr4_+_6572364 1.20 ENSDART00000122574
protein phosphatase 1, regulatory subunit 3Aa
chr19_+_40983221 1.19 ENSDART00000144544
collagen, type I, alpha 2
chr18_+_23218980 1.19 ENSDART00000185014
myocyte enhancer factor 2aa
chr16_-_22713152 1.19 ENSDART00000140953
ENSDART00000143836
si:ch211-105c13.3
chr7_-_35515931 1.18 ENSDART00000193324
iroquois homeobox 6a
chr15_+_31886284 1.18 ENSDART00000156706
furry homolog a (Drosophila)
chr3_-_30609659 1.15 ENSDART00000182516
ENSDART00000187047
ENSDART00000110597
synaptotagmin III
chr7_+_42206847 1.13 ENSDART00000149250
phosphorylase kinase, beta
chr9_-_23891102 1.12 ENSDART00000186799
ankyrin repeat and SOCS box containing 18
chr7_-_3927813 1.12 ENSDART00000172991
ENSDART00000173392
si:dkey-88n24.12
chr6_+_57541776 1.12 ENSDART00000157330
N-terminal EF-hand calcium binding protein 3
chr22_-_29689485 1.11 ENSDART00000182173
programmed cell death 4b
chr17_+_43468732 1.09 ENSDART00000055487
charged multivesicular body protein 3
chr7_+_69841017 1.09 ENSDART00000169107

chr15_+_20543770 1.08 ENSDART00000092357
small G protein signaling modulator 2
chr23_-_35545554 1.07 ENSDART00000147915
ALK and LTK ligand 2a
chr14_+_24215046 1.07 ENSDART00000079215
stanniocalcin 2a
chr9_-_30808073 1.06 ENSDART00000146300
Kruppel-like factor 5b
chr9_-_23894392 1.06 ENSDART00000133417
ankyrin repeat and SOCS box containing 18
chr16_-_17188294 1.03 ENSDART00000165883
opsin 9
chr7_-_31938938 1.03 ENSDART00000132353
brain-derived neurotrophic factor
chr23_+_17354154 1.01 ENSDART00000155808
zgc:194282
chr16_-_17200120 1.00 ENSDART00000147739
glyceraldehyde-3-phosphate dehydrogenase
chr7_-_41964877 0.99 ENSDART00000092351
ENSDART00000193395
ENSDART00000187947
neuropilin (NRP) and tolloid (TLL)-like 2b
chr21_+_40944530 0.99 ENSDART00000022976
potassium channel tetramerization domain containing 16b
chr25_+_28679672 0.98 ENSDART00000139965
ENSDART00000134072
CCR4-NOT transcription complex, subunit 2

Network of associatons between targets according to the STRING database.

First level regulatory network of mef2d

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 GO:0097264 self proteolysis(GO:0097264)
1.4 7.0 GO:0003210 cardiac atrium formation(GO:0003210)
1.2 3.7 GO:0006957 complement activation, alternative pathway(GO:0006957) regulation of protein activation cascade(GO:2000257)
1.2 14.8 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
1.1 3.4 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857)
1.0 4.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.9 4.5 GO:0097066 response to thyroid hormone(GO:0097066)
0.8 3.2 GO:0010561 negative regulation of glycoprotein biosynthetic process(GO:0010561) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) negative regulation of glycoprotein metabolic process(GO:1903019)
0.8 4.8 GO:0007603 phototransduction, visible light(GO:0007603)
0.8 10.5 GO:0032264 IMP salvage(GO:0032264)
0.7 2.1 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.7 5.7 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.7 9.0 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.6 1.8 GO:0010265 SCF complex assembly(GO:0010265)
0.6 1.7 GO:0061355 Wnt protein secretion(GO:0061355)
0.5 1.6 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
0.5 4.3 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.5 1.5 GO:0052576 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
0.5 1.5 GO:0003091 renal water homeostasis(GO:0003091) renal water transport(GO:0003097)
0.5 3.9 GO:0090594 inflammatory response to wounding(GO:0090594)
0.5 1.4 GO:0006585 dopamine biosynthetic process from tyrosine(GO:0006585) dopamine biosynthetic process(GO:0042416)
0.4 6.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.4 2.4 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.4 4.2 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.4 2.3 GO:0016081 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.4 1.1 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.4 3.7 GO:0006450 regulation of translational fidelity(GO:0006450)
0.4 1.4 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.3 1.7 GO:0051145 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
0.3 3.3 GO:0006108 malate metabolic process(GO:0006108)
0.3 1.6 GO:0021731 trigeminal motor nucleus development(GO:0021731)
0.3 2.8 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.3 2.0 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.3 4.6 GO:0046549 retinal cone cell development(GO:0046549)
0.3 1.6 GO:0008584 male gonad development(GO:0008584)
0.3 1.3 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703) multi-organism behavior(GO:0051705)
0.2 5.4 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.2 1.4 GO:0071305 vitamin D3 metabolic process(GO:0070640) cellular response to vitamin D(GO:0071305)
0.2 1.9 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 2.2 GO:0015800 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.2 4.0 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2 0.9 GO:0070166 enamel mineralization(GO:0070166)
0.2 0.6 GO:0030043 actin filament fragmentation(GO:0030043)
0.2 3.0 GO:0035493 SNARE complex assembly(GO:0035493)
0.2 0.8 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.2 3.0 GO:0015858 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.2 0.8 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.2 2.9 GO:0016486 peptide hormone processing(GO:0016486)
0.2 2.5 GO:0090303 positive regulation of wound healing(GO:0090303)
0.2 5.5 GO:0051180 vitamin transport(GO:0051180)
0.2 1.1 GO:0070375 ERK5 cascade(GO:0070375) regulation of ERK5 cascade(GO:0070376) positive regulation of ERK5 cascade(GO:0070378)
0.2 9.4 GO:0006096 glycolytic process(GO:0006096)
0.2 2.2 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.2 1.6 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.2 7.3 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.7 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 1.0 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.5 GO:0045730 respiratory burst(GO:0045730)
0.1 0.8 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 0.5 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186) peptidyl-glutamine modification(GO:0018199)
0.1 5.7 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.1 0.9 GO:0003207 cardiac chamber formation(GO:0003207)
0.1 4.2 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.1 1.7 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 1.3 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 2.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.9 GO:0021634 optic nerve formation(GO:0021634)
0.1 1.1 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.1 1.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.9 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.1 3.8 GO:0042770 signal transduction in response to DNA damage(GO:0042770)
0.1 1.8 GO:0014823 response to activity(GO:0014823)
0.1 8.7 GO:0048469 cell maturation(GO:0048469)
0.1 4.0 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 1.5 GO:0007622 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.1 2.6 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 3.3 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.9 GO:0060612 adipose tissue development(GO:0060612)
0.1 0.7 GO:0006566 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.1 0.7 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 0.9 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 0.8 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 3.4 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 0.8 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 1.6 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 3.9 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.1 1.7 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 0.7 GO:0071715 icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571)
0.1 0.6 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 3.1 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 0.4 GO:0042693 muscle cell fate commitment(GO:0042693)
0.1 3.4 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.1 0.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 1.2 GO:0010737 protein kinase A signaling(GO:0010737)
0.1 0.3 GO:0034164 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 0.7 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.1 0.6 GO:0061709 reticulophagy(GO:0061709)
0.1 1.4 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 0.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.2 GO:0070285 pigment cell development(GO:0070285)
0.1 2.0 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.1 1.3 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.1 3.9 GO:0021549 cerebellum development(GO:0021549)
0.1 1.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 3.5 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 1.0 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.2 GO:0006833 water transport(GO:0006833)
0.0 0.3 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 2.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 3.8 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 2.2 GO:1901214 regulation of neuron death(GO:1901214)
0.0 5.3 GO:0006936 muscle contraction(GO:0006936)
0.0 1.2 GO:0051014 actin filament severing(GO:0051014)
0.0 2.0 GO:0007602 phototransduction(GO:0007602)
0.0 4.0 GO:0031101 fin regeneration(GO:0031101)
0.0 3.0 GO:1902652 cholesterol metabolic process(GO:0008203) secondary alcohol metabolic process(GO:1902652)
0.0 0.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 1.4 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 3.7 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 1.8 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 2.1 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 1.1 GO:0048634 regulation of muscle organ development(GO:0048634)
0.0 0.5 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 1.0 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.0 0.7 GO:0003171 atrioventricular valve development(GO:0003171)
0.0 1.2 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 3.3 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.5 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.6 GO:0016233 telomere capping(GO:0016233)
0.0 0.2 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) reelin-mediated signaling pathway(GO:0038026)
0.0 0.6 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 1.7 GO:0000045 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 0.4 GO:0036065 fucosylation(GO:0036065)
0.0 0.5 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.1 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.5 GO:1904894 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.0 1.6 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.8 GO:0006956 complement activation(GO:0006956)
0.0 1.6 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.1 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 1.3 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 1.2 GO:0009612 response to mechanical stimulus(GO:0009612)
0.0 2.7 GO:0007601 visual perception(GO:0007601)
0.0 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 2.3 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 1.4 GO:0006979 response to oxidative stress(GO:0006979)
0.0 1.9 GO:0061053 somite development(GO:0061053)
0.0 1.4 GO:0006814 sodium ion transport(GO:0006814)
0.0 0.1 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.7 5.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.6 3.9 GO:0030891 VCB complex(GO:0030891)
0.5 10.7 GO:0031430 M band(GO:0031430)
0.4 3.4 GO:0016586 RSC complex(GO:0016586)
0.4 5.0 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.4 4.5 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2 3.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.2 2.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2 4.0 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.2 2.2 GO:0042583 chromaffin granule(GO:0042583)
0.2 3.0 GO:0034361 very-low-density lipoprotein particle(GO:0034361)
0.2 5.9 GO:0031594 neuromuscular junction(GO:0031594)
0.2 2.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.2 7.3 GO:0005861 troponin complex(GO:0005861)
0.2 1.6 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 1.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.7 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 2.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 2.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 1.9 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 1.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 1.4 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.8 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 4.1 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.8 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.1 0.9 GO:0002142 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.1 1.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 3.9 GO:0008305 integrin complex(GO:0008305)
0.1 5.5 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 1.0 GO:0000815 ESCRT III complex(GO:0000815)
0.1 2.9 GO:0031941 filamentous actin(GO:0031941)
0.1 2.4 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 1.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.4 GO:0043204 perikaryon(GO:0043204)
0.0 1.0 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.7 GO:0016605 PML body(GO:0016605)
0.0 1.4 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.6 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 2.7 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.9 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.6 GO:0070187 telosome(GO:0070187)
0.0 0.2 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 6.2 GO:0070382 exocytic vesicle(GO:0070382)
0.0 2.3 GO:0030018 Z disc(GO:0030018)
0.0 0.6 GO:0035102 PRC1 complex(GO:0035102)
0.0 2.0 GO:0005581 collagen trimer(GO:0005581)
0.0 0.7 GO:0032590 neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590)
0.0 7.4 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.5 GO:0031985 Golgi cisterna(GO:0031985)
0.0 2.0 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.0 GO:0043025 neuronal cell body(GO:0043025)
0.0 2.8 GO:0030424 axon(GO:0030424)
0.0 1.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.5 GO:0005795 Golgi stack(GO:0005795)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 15.3 GO:0005615 extracellular space(GO:0005615)
0.0 1.3 GO:0000786 nucleosome(GO:0000786)
0.0 0.8 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.0 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 12.1 GO:0005739 mitochondrion(GO:0005739)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 9.0 GO:0003796 lysozyme activity(GO:0003796)
1.8 5.5 GO:0005499 vitamin D binding(GO:0005499)
1.6 6.5 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
1.4 8.4 GO:0004743 pyruvate kinase activity(GO:0004743)
1.0 4.8 GO:0050254 rhodopsin kinase activity(GO:0050254)
1.0 10.5 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.8 3.3 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.8 3.8 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.7 3.0 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.7 5.7 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.7 5.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.7 9.0 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.5 5.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.4 2.0 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.4 2.8 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.4 15.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.4 3.0 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.4 3.0 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.3 1.5 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.3 1.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.3 1.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 2.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.3 0.8 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.3 4.3 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.3 1.0 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.2 2.5 GO:0016936 galactoside binding(GO:0016936)
0.2 1.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.2 0.7 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.2 1.3 GO:0004962 endothelin receptor activity(GO:0004962)
0.2 2.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.2 1.1 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.2 0.5 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.2 1.4 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 2.2 GO:0051117 ATPase binding(GO:0051117)
0.1 0.7 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.1 2.9 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 2.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.6 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.1 3.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 3.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.5 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1 3.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 1.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 3.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 2.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 3.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.8 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 3.8 GO:0019003 GDP binding(GO:0019003)
0.1 1.6 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.4 GO:0071253 connexin binding(GO:0071253)
0.1 2.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.6 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 1.6 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 1.9 GO:0005523 tropomyosin binding(GO:0005523)
0.1 3.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 0.9 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.1 3.7 GO:0000049 tRNA binding(GO:0000049)
0.1 2.6 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 1.0 GO:0005165 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.1 3.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 4.2 GO:0005178 integrin binding(GO:0005178)
0.1 6.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.9 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.7 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 13.5 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.1 0.9 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.9 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.8 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 1.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 1.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.9 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.1 1.7 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 2.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.7 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 2.4 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 2.0 GO:0015296 anion:cation symporter activity(GO:0015296)
0.0 0.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 2.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 2.5 GO:0046332 SMAD binding(GO:0046332)
0.0 2.0 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 1.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.0 0.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0005372 water transmembrane transporter activity(GO:0005372)
0.0 0.4 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.4 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.8 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 1.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 2.2 GO:0015293 symporter activity(GO:0015293)
0.0 0.1 GO:0070186 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 22.5 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.4 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.9 GO:0044325 ion channel binding(GO:0044325)
0.0 1.0 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 1.5 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 1.9 GO:0008083 growth factor activity(GO:0008083)
0.0 0.3 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 3.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.9 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 5.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 4.4 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.2 3.0 PID REELIN PATHWAY Reelin signaling pathway
0.1 2.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 2.7 NABA COLLAGENS Genes encoding collagen proteins
0.1 0.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 2.1 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.7 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.1 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.0 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.4 PID SHP2 PATHWAY SHP2 signaling
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.4 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.8 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.4 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
1.4 4.1 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.9 8.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.4 2.9 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.3 9.3 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.3 7.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.2 4.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 1.6 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.2 1.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.2 2.0 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 4.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 0.7 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 1.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 0.9 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 0.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 3.9 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.9 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.0 0.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide