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PRJEB1986: zebrafish developmental stages transcriptome

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Results for mef2ca+mef2cb

Z-value: 1.09

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Transcription factors associated with mef2ca+mef2cb

Gene Symbol Gene ID Gene Info
ENSDARG00000009418 myocyte enhancer factor 2cb
ENSDARG00000029764 myocyte enhancer factor 2ca

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mef2cbdr11_v1_chr5_-_48285756_482857560.725.0e-04Click!
mef2cadr11_v1_chr10_-_43611643_436117180.522.4e-02Click!

Activity profile of mef2ca+mef2cb motif

Sorted Z-values of mef2ca+mef2cb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_45677781 4.60 ENSDART00000163120
ENSDART00000126537
group-specific component (vitamin D binding protein)
chr25_+_31222069 4.39 ENSDART00000159373
troponin I type 2a (skeletal, fast), tandem duplicate 1
chr3_-_61205711 4.27 ENSDART00000055062
parvalbumin 1
chr24_-_4765740 3.86 ENSDART00000121576
carboxypeptidase B1 (tissue)
chr14_+_32838110 3.78 ENSDART00000158077
arrestin 3b, retinal (X-arrestin)
chr6_-_12588044 3.41 ENSDART00000047896
solute carrier family 15 (oligopeptide transporter), member 1b
chr12_-_4028079 3.22 ENSDART00000128676
si:ch211-180a12.2
chr21_+_11684830 3.14 ENSDART00000147473
proprotein convertase subtilisin/kexin type 1
chr5_+_51597677 3.09 ENSDART00000048210
ENSDART00000184797
creatine kinase, mitochondrial 2b (sarcomeric)
chr2_+_16536453 2.94 ENSDART00000100287
G protein-coupled receptor kinase 7a
chr9_-_52814204 2.91 ENSDART00000140771
ENSDART00000007401
si:ch211-45c16.2
chr8_+_52637507 2.87 ENSDART00000163830
si:dkey-90l8.3
chr25_+_14092871 2.83 ENSDART00000067239
guanylate cyclase activator 1g
chr14_+_32837914 2.69 ENSDART00000158888
arrestin 3b, retinal (X-arrestin)
chr1_-_43915423 2.68 ENSDART00000181915
ENSDART00000113673
secretory calcium-binding phosphoprotein 5
chr8_+_34731982 2.58 ENSDART00000066050
4-hydroxyphenylpyruvate dioxygenase b
chr11_-_43104475 2.55 ENSDART00000125368
acylphosphatase 2, muscle type
chr21_+_11685009 2.51 ENSDART00000014668
proprotein convertase subtilisin/kexin type 1
chr17_-_12336987 2.46 ENSDART00000172001
synaptosomal-associated protein, 25b
chr25_+_29160102 2.36 ENSDART00000162854
pyruvate kinase M1/2b
chr7_+_15266093 2.34 ENSDART00000124676
synaptic vesicle glycoprotein 2Ba
chr1_+_8601935 2.27 ENSDART00000152367
si:ch211-160d14.6
chr7_-_71758307 2.15 ENSDART00000161067
ENSDART00000165253
myomesin 1b
chr16_-_43026273 2.10 ENSDART00000156820
ENSDART00000189080
si:dkey-7j14.5
chr10_-_22845485 2.08 ENSDART00000079454
vesicle-associated membrane protein 2
chr3_+_26135502 2.05 ENSDART00000146979
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr16_-_19890303 2.04 ENSDART00000147161
ENSDART00000079159
histone deacetylase 9b
chr2_-_43168292 2.01 ENSDART00000132588
cAMP responsive element modulator a
chr13_-_2189761 1.98 ENSDART00000166255
muscular LMNA-interacting protein
chr9_-_42873700 1.92 ENSDART00000125953
titin, tandem duplicate 1
chr10_-_41450367 1.92 ENSDART00000122682
ENSDART00000189549
calcium binding protein 1b
chr25_+_16945348 1.89 ENSDART00000016591
fibroblast growth factor 6a
chr10_-_24371312 1.85 ENSDART00000149362
phosphatidylinositol transfer protein, alpha b
chr18_+_7264961 1.84 ENSDART00000188461

chr21_+_12010505 1.84 ENSDART00000123522
aquaporin 7
chr3_-_49504023 1.82 ENSDART00000168108
protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a
chr20_+_13175379 1.81 ENSDART00000025644
protein phosphatase 2, regulatory subunit B', alpha isoform
chr10_-_24362775 1.75 ENSDART00000182104
phosphatidylinositol transfer protein, alpha b
chr23_+_17220986 1.73 ENSDART00000054761
nucleolar protein 4-like b
chr6_-_38816500 1.65 ENSDART00000190866
ENSDART00000104124
cyclic nucleotide gated channel alpha 3a
chr15_-_9031996 1.64 ENSDART00000124998
reticulon 2a
chr22_+_17205608 1.64 ENSDART00000181267
RAB3B, member RAS oncogene family
chr7_+_41295974 1.59 ENSDART00000173568
ENSDART00000173544
si:dkey-86l18.10
chr11_+_6819050 1.59 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr12_-_17707449 1.59 ENSDART00000142427
ENSDART00000034914
parvalbumin 3
chr23_+_6077503 1.57 ENSDART00000081714
ENSDART00000139834
myosin binding protein Ha
chr6_-_35472923 1.56 ENSDART00000185907
regulator of G protein signaling 8
chr20_-_39271844 1.56 ENSDART00000192708
clusterin
chr1_-_8101495 1.52 ENSDART00000161938
si:dkeyp-9d4.3
chr10_+_29698467 1.52 ENSDART00000163402
discs, large homolog 2 (Drosophila)
chr4_+_5180650 1.51 ENSDART00000067390
fibroblast growth factor 6b
chr18_+_40355408 1.50 ENSDART00000167134
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like
chr17_-_50233493 1.49 ENSDART00000172266
v-fos FBJ murine osteosarcoma viral oncogene homolog Aa
chr16_-_17541890 1.49 ENSDART00000131328
chloride channel, voltage-sensitive 1b
chr1_+_19708508 1.49 ENSDART00000054581
ENSDART00000131206
membrane-associated ring finger (C3HC4) 1
chr20_+_23173710 1.48 ENSDART00000074172
sarcoglycan, beta (dystrophin-associated glycoprotein)
chr7_-_41964877 1.45 ENSDART00000092351
ENSDART00000193395
ENSDART00000187947
neuropilin (NRP) and tolloid (TLL)-like 2b
chr25_+_35212919 1.45 ENSDART00000180127
anoctamin 5a
chr12_-_13886952 1.44 ENSDART00000110503
ADAM metallopeptidase domain 11
chr3_+_23092762 1.43 ENSDART00000142884
ENSDART00000024136
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a
chr6_+_11250033 1.42 ENSDART00000065411
ENSDART00000132677
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr3_+_59851537 1.42 ENSDART00000180997

chr5_+_62356304 1.41 ENSDART00000148381
aspartoacylase
chr11_+_25430851 1.41 ENSDART00000164999
ENSDART00000126403
si:dkey-13a21.4
chr2_+_6181383 1.40 ENSDART00000153307
si:ch73-344o19.1
chr14_+_23811808 1.40 ENSDART00000014411
potassium channel tetramerization domain containing 16a
chr3_-_30123113 1.39 ENSDART00000153562
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr23_-_7826849 1.39 ENSDART00000157612
myelin transcription factor 1b
chr25_+_14165447 1.39 ENSDART00000145387
SH3 and multiple ankyrin repeat domains 2
chr5_-_10946232 1.37 ENSDART00000163139
ENSDART00000031265
reticulon 4 receptor
chr16_+_25245857 1.37 ENSDART00000155220
kelch-like family member 38b
chr3_+_1735214 1.37 ENSDART00000185454

chr7_-_13381129 1.34 ENSDART00000164326
si:ch73-119p20.1
chr4_+_11375894 1.34 ENSDART00000190471
ENSDART00000143963
piccolo presynaptic cytomatrix protein a
chr17_-_43558494 1.33 ENSDART00000103830
5'-nucleotidase, cytosolic IAb
chr3_+_28953274 1.32 ENSDART00000133528
ENSDART00000103602
lectin, galactoside-binding, soluble, 2a
chr7_-_42206720 1.30 ENSDART00000110907
integrin alpha FG-GAP repeat containing 1
chr17_-_50234004 1.30 ENSDART00000058706
v-fos FBJ murine osteosarcoma viral oncogene homolog Aa
chr13_-_11536951 1.28 ENSDART00000018155
adenylosuccinate synthase
chr13_-_27767330 1.28 ENSDART00000131631
ENSDART00000112553
ENSDART00000189911
regulating synaptic membrane exocytosis 1a
chr6_-_49547680 1.27 ENSDART00000169678
protein phosphatase 4, regulatory subunit 1-like
chr9_-_43073960 1.27 ENSDART00000059460
titin, tandem duplicate 2
chr25_-_12809361 1.27 ENSDART00000162750
carbonic anhydrase Va
chr23_-_18030399 1.27 ENSDART00000136967
peptidase M20 domain containing 1, tandem duplicate 1
chr15_-_34845414 1.26 ENSDART00000009892
gamma-aminobutyric acid (GABA) B receptor, 1a
chr8_-_32497815 1.25 ENSDART00000122359
si:dkey-164f24.2
chr23_-_35347714 1.25 ENSDART00000161770
ENSDART00000165615
copine family member IX
chr7_-_71758613 1.24 ENSDART00000166724
myomesin 1b
chr14_-_27297123 1.23 ENSDART00000173423
protocadherin 11
chr10_-_2522588 1.23 ENSDART00000081926

chr9_+_29643036 1.23 ENSDART00000023210
ENSDART00000175160
tripartite motif containing 13
chr3_-_49138004 1.22 ENSDART00000167173
GIPC PDZ domain containing family, member 1
chr18_-_25177230 1.21 ENSDART00000013363
solute carrier organic anion transporter family, member 3A1
chr15_-_29162193 1.21 ENSDART00000138449
ENSDART00000099885
XIAP associated factor 1
chr23_-_27633730 1.21 ENSDART00000103639
ADP-ribosylation factor 3a
chr19_+_24394560 1.20 ENSDART00000142506
si:dkey-81h8.1
chr23_-_7125494 1.18 ENSDART00000111929
solute carrier organic anion transporter family, member 4A1
chr3_-_14103551 1.15 ENSDART00000127604
nuclear factor, interleukin 3 regulated, member 6
chr21_-_25685739 1.15 ENSDART00000129619
ENSDART00000101205
phosphorylase kinase, gamma 1b (muscle)
chr23_+_17981127 1.15 ENSDART00000012571
ENSDART00000145200
chitinase, acidic.6
chr7_-_31321027 1.14 ENSDART00000186878

chr6_+_8079974 1.14 ENSDART00000152071
si:ch211-207j7.2
chr1_-_49250490 1.14 ENSDART00000150386
si:ch73-6k14.2
chr16_-_17188294 1.13 ENSDART00000165883
opsin 9
chr13_+_22249636 1.13 ENSDART00000108472
ENSDART00000173123
synaptopodin 2-like a
chr9_+_22632126 1.13 ENSDART00000139434
ets variant 5a
chr5_-_29122834 1.13 ENSDART00000087197
whirlin b
chr15_+_40008370 1.12 ENSDART00000063783
integral membrane protein 2Ca
chr23_-_38497705 1.11 ENSDART00000109493
teashirt zinc finger homeobox 2
chr6_+_11250316 1.11 ENSDART00000137122
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr10_+_22724059 1.10 ENSDART00000136123
lysine (K)-specific demethylase 6B, b
chr3_-_5016893 1.09 ENSDART00000165968
cold shock domain containing C2
chr8_+_30456161 1.09 ENSDART00000085894
phosphoglucomutase 5
chr8_-_49935358 1.08 ENSDART00000159782
ENSDART00000156841
ATP/GTP binding protein 1

chr15_+_20543770 1.07 ENSDART00000092357
small G protein signaling modulator 2
chr20_-_7000225 1.06 ENSDART00000100098
adenylate cyclase 1a
chr18_+_23193820 1.05 ENSDART00000148106
myocyte enhancer factor 2aa
chr16_-_43356018 1.05 ENSDART00000181683

chr17_-_39886628 1.04 ENSDART00000002217
zmp:0000000545
chr20_+_18163821 1.03 ENSDART00000186507
aquaporin 4
chr21_+_43559123 1.02 ENSDART00000151212
G protein-coupled receptor 185 a
chr10_+_41765616 1.01 ENSDART00000170682
ring finger protein 34b
chr16_+_21738194 1.00 ENSDART00000163688
Danio rerio si:ch211-154o6.4 (si:ch211-154o6.4), mRNA.
chr4_-_4119396 0.98 ENSDART00000067409
ENSDART00000138221
leiomodin 2 (cardiac) b
chr24_+_34085940 0.97 ENSDART00000171189
ankyrin repeat and SOCS box containing 10
chr12_+_1000323 0.97 ENSDART00000054363
si:ch1073-272o11.3
chr17_-_722218 0.97 ENSDART00000160385
solute carrier family 25 member 29
chr21_+_9997418 0.97 ENSDART00000181454
ENSDART00000171579
hect domain and RLD 7
chr6_+_11438972 0.96 ENSDART00000029314
collagen, type V, alpha 2b
chr2_+_6885852 0.96 ENSDART00000016607
regulator of G protein signaling 5b
chr7_+_13830052 0.95 ENSDART00000191360
abhydrolase domain containing 2a
chr9_-_23891102 0.95 ENSDART00000186799
ankyrin repeat and SOCS box containing 18
chr2_-_37353098 0.95 ENSDART00000056522
SKI-like proto-oncogene a
chr11_+_25634041 0.93 ENSDART00000033657
glutamate receptor, metabotropic 6b
chr15_+_32867420 0.93 ENSDART00000159442
doublecortin-like kinase 1b
chr19_+_2590182 0.93 ENSDART00000162293
si:ch73-345f18.3
chr23_+_17980875 0.92 ENSDART00000163452
chitinase, acidic.6
chr4_-_72080351 0.92 ENSDART00000174925

chr11_+_11201096 0.92 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myomesin 2a
chr3_-_42981739 0.91 ENSDART00000167844
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
chr11_-_19650781 0.91 ENSDART00000165595
si:dkey-30j16.3
chr9_+_45227028 0.91 ENSDART00000185579
adenosine deaminase, RNA-specific, B1b
chr22_-_8509215 0.90 ENSDART00000140146
si:ch73-27e22.3
chr21_+_40944530 0.90 ENSDART00000022976
potassium channel tetramerization domain containing 16b
chr5_+_22264051 0.90 ENSDART00000143314
Rho GTPase activating protein 20b
chr16_-_22683038 0.89 ENSDART00000138130
S100 calcium binding protein T
chr12_-_26064480 0.88 ENSDART00000158215
ENSDART00000171206
ENSDART00000171212
ENSDART00000182956
ENSDART00000186779
LIM domain binding 3b
chr3_-_30609659 0.88 ENSDART00000182516
ENSDART00000187047
ENSDART00000110597
synaptotagmin III
chr14_+_11909966 0.88 ENSDART00000171829
FERM and PDZ domain containing 3
chr16_-_4026265 0.88 ENSDART00000149339
si:ch211-175f12.2
chr19_-_9662958 0.88 ENSDART00000041094
chloride channel, voltage-sensitive 1a
chr21_+_40589770 0.88 ENSDART00000164650
ENSDART00000161584
ENSDART00000161108
pyruvate dehydrogenase kinase, isozyme 3b
chr12_+_32323098 0.87 ENSDART00000188722
si:ch211-277e21.2
chr1_+_50968908 0.87 ENSDART00000150353
ENSDART00000012842
malate dehydrogenase 1Aa, NAD (soluble)
chr20_+_16881883 0.86 ENSDART00000130107
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a
chr24_-_21490628 0.86 ENSDART00000181546
ATPase phospholipid transporting 8A2
chr3_+_44947355 0.86 ENSDART00000083040
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr11_+_11200550 0.85 ENSDART00000181339
ENSDART00000187116
myomesin 2a
chr12_+_47794089 0.84 ENSDART00000160726
polymerase (RNA) III (DNA directed) polypeptide A
chr2_-_8611675 0.83 ENSDART00000138223
si:ch211-71m22.1
chr1_-_9195629 0.83 ENSDART00000143587
ENSDART00000192174
endoplasmic reticulum to nucleus signaling 2
chr20_+_34455645 0.83 ENSDART00000135789
methyltransferase like 11B
chr7_+_69356661 0.83 ENSDART00000177049

chr10_+_40836378 0.83 ENSDART00000085792
tripartite motif containing 69
chr11_-_1948784 0.82 ENSDART00000082475
nuclear receptor subfamily 1, group D, member 4b
chr10_+_37145007 0.82 ENSDART00000131777
CUE domain containing 1a
chr1_+_31113951 0.82 ENSDART00000129362
eukaryotic translation elongation factor 1 alpha 1b
chr8_+_22930627 0.81 ENSDART00000187860
synaptophysin a
chr7_+_42206847 0.79 ENSDART00000149250
phosphorylase kinase, beta
chr13_+_31172833 0.79 ENSDART00000176378

chr5_-_29122615 0.78 ENSDART00000144802
whirlin b
chr14_+_30291611 0.78 ENSDART00000173004
microtubule associated tumor suppressor 1a
chr4_+_6572364 0.78 ENSDART00000122574
protein phosphatase 1, regulatory subunit 3Aa
chr7_-_7420301 0.77 ENSDART00000102620
SIX homeobox 7
chr19_-_12648122 0.77 ENSDART00000151184
family with sequence similarity 210, member Aa
chr20_+_41549200 0.77 ENSDART00000135715
family with sequence similarity 184, member A
chr18_+_23193567 0.77 ENSDART00000190072
ENSDART00000171594
ENSDART00000181762
myocyte enhancer factor 2aa
chr10_-_2527342 0.76 ENSDART00000184168

chr1_-_1885516 0.76 ENSDART00000122187
ENSDART00000131675
si:ch211-132g1.3
chr18_-_8579907 0.76 ENSDART00000147284
si:ch211-220f12.1
chr8_+_47571211 0.76 ENSDART00000131460
phospholipase C, eta 2a
chr1_-_38813679 0.75 ENSDART00000148917
ankyrin repeat and SOCS box containing 5b
chr18_-_12416019 0.75 ENSDART00000144799
si:ch211-1e14.1
chr6_-_14139503 0.75 ENSDART00000089577
calcium channel, voltage-dependent, beta 4b subunit
chr23_-_1557195 0.74 ENSDART00000136436
epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
chr1_+_7546259 0.74 ENSDART00000015732
myosin, light polypeptide 3, skeletal muscle
chr25_-_31118923 0.74 ENSDART00000009126
ENSDART00000188286
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
chr5_-_25236340 0.73 ENSDART00000162774
ATP-binding cassette, sub-family A (ABC1), member 2
chr3_+_59051503 0.72 ENSDART00000160767
rasd family member 4
chr13_+_12175724 0.72 ENSDART00000166053
gamma-aminobutyric acid type A receptor gamma1 subunit
chr6_-_30859656 0.72 ENSDART00000156235
phosphodiesterase 4B, cAMP-specific a
chr20_-_40360571 0.72 ENSDART00000144768
sphingomyelin phosphodiesterase, acid-like 3A
chr16_+_5259886 0.71 ENSDART00000186668
plectin b
chr17_-_50374005 0.71 ENSDART00000149773
otoferlin b
chr8_-_32497581 0.69 ENSDART00000176298
ENSDART00000183340
si:dkey-164f24.2
chr18_+_23218980 0.69 ENSDART00000185014
myocyte enhancer factor 2aa
chr9_+_38088331 0.68 ENSDART00000123749
calcium channel, voltage-dependent, beta 4a subunit
chr11_-_18254 0.68 ENSDART00000167814
proline rich 13
chr25_-_8160030 0.67 ENSDART00000067159
tryptophan hydroxylase 1 (tryptophan 5-monooxygenase) a
chr21_+_15870752 0.67 ENSDART00000122015
family with sequence similarity 169, member Ab

Network of associatons between targets according to the STRING database.

First level regulatory network of mef2ca+mef2cb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.5 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.5 1.6 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.5 2.6 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.5 2.9 GO:0007603 phototransduction, visible light(GO:0007603)
0.4 2.6 GO:0006572 tyrosine catabolic process(GO:0006572)
0.4 1.6 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.4 3.4 GO:0006857 oligopeptide transport(GO:0006857)
0.4 5.6 GO:0016486 peptide hormone processing(GO:0016486)
0.4 1.5 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.3 1.4 GO:0003322 pancreatic A cell development(GO:0003322)
0.3 1.3 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.3 0.9 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
0.3 1.1 GO:0042985 negative regulation of glycoprotein biosynthetic process(GO:0010561) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) negative regulation of glycoprotein metabolic process(GO:1903019)
0.3 1.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.3 2.5 GO:0044805 late nucleophagy(GO:0044805)
0.2 2.9 GO:0006599 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.2 1.4 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.2 1.8 GO:0071331 cellular response to carbohydrate stimulus(GO:0071322) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.2 3.2 GO:0048769 sarcomerogenesis(GO:0048769)
0.2 1.0 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.2 2.1 GO:0006032 chitin catabolic process(GO:0006032)
0.2 0.5 GO:0090131 mesenchyme migration(GO:0090131)
0.2 1.4 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.2 2.5 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 0.9 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.2 0.8 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.2 3.2 GO:0006910 phagocytosis, recognition(GO:0006910)
0.2 2.3 GO:0015858 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.1 1.0 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 2.1 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.4 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 2.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 1.3 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.1 0.4 GO:0045730 respiratory burst(GO:0045730)
0.1 1.3 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.1 3.4 GO:0051180 vitamin transport(GO:0051180)
0.1 1.0 GO:0006833 water transport(GO:0006833)
0.1 0.4 GO:0055064 chloride ion homeostasis(GO:0055064)
0.1 0.7 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1 1.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 1.0 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 4.9 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 1.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.3 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.1 1.3 GO:0090303 positive regulation of wound healing(GO:0090303)
0.1 1.9 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 0.4 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.1 1.8 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 0.6 GO:0061709 reticulophagy(GO:0061709)
0.1 0.3 GO:0070166 enamel mineralization(GO:0070166)
0.1 2.6 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.1 0.7 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 4.5 GO:0015914 phospholipid transport(GO:0015914)
0.1 0.3 GO:0035521 monoubiquitinated protein deubiquitination(GO:0035520) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.3 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 2.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.7 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 0.5 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 1.4 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 1.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.7 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 1.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 0.5 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.1 0.5 GO:0002698 negative regulation of immune effector process(GO:0002698)
0.0 0.8 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.5 GO:0044247 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 2.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 1.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 1.4 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 1.2 GO:0044773 mitotic DNA damage checkpoint(GO:0044773)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.4 GO:0050975 sensory perception of touch(GO:0050975)
0.0 1.8 GO:0007602 phototransduction(GO:0007602)
0.0 0.4 GO:0009583 detection of light stimulus(GO:0009583)
0.0 2.4 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.0 0.1 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.0 3.8 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.7 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.2 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.0 0.7 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 3.9 GO:0006821 chloride transport(GO:0006821)
0.0 3.3 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 3.2 GO:0006936 muscle contraction(GO:0006936)
0.0 0.2 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.0 0.3 GO:0048041 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.0 0.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.1 GO:1901072 glucosamine-containing compound catabolic process(GO:1901072)
0.0 1.1 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.0 0.3 GO:0033151 V(D)J recombination(GO:0033151)
0.0 0.2 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.1 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.0 0.4 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.6 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 1.3 GO:1901214 regulation of neuron death(GO:1901214)
0.0 1.0 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.9 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.0 0.8 GO:0006073 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 0.5 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.4 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0 0.5 GO:0009408 response to heat(GO:0009408)
0.0 1.3 GO:0021549 cerebellum development(GO:0021549)
0.0 1.1 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 2.3 GO:0051260 protein homooligomerization(GO:0051260)
0.0 1.6 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.4 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.4 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.3 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.6 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 1.4 GO:0007269 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.4 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.6 GO:0061035 regulation of cartilage development(GO:0061035)
0.0 0.6 GO:0048634 regulation of muscle organ development(GO:0048634)
0.0 0.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.0 GO:0002093 auditory receptor cell morphogenesis(GO:0002093)
0.0 1.1 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 0.7 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.2 GO:0036294 cellular response to decreased oxygen levels(GO:0036294) cellular response to hypoxia(GO:0071456)
0.0 0.6 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.4 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 1.7 GO:0007601 visual perception(GO:0007601)
0.0 0.2 GO:2000134 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0031673 H zone(GO:0031673)
0.4 2.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.3 0.8 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.2 1.0 GO:0005588 collagen type V trimer(GO:0005588)
0.2 1.0 GO:0097524 sperm plasma membrane(GO:0097524)
0.2 1.9 GO:0002142 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.2 4.4 GO:0031430 M band(GO:0031430)
0.2 1.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.2 3.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.2 1.9 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.2 1.3 GO:0038039 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.2 1.6 GO:0042583 chromaffin granule(GO:0042583)
0.2 2.0 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 0.4 GO:0032998 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.1 1.3 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 4.8 GO:0005861 troponin complex(GO:0005861)
0.1 0.2 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 2.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 1.6 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 1.4 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.3 GO:0016460 myosin II complex(GO:0016460)
0.1 0.3 GO:0097519 DNA recombinase complex(GO:0097519)
0.1 1.3 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.1 1.0 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 1.5 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 3.9 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 1.3 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 1.4 GO:0048786 presynaptic active zone(GO:0048786)
0.1 1.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 1.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 2.1 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 1.7 GO:0031594 neuromuscular junction(GO:0031594)
0.1 2.0 GO:0016605 PML body(GO:0016605)
0.1 0.7 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 1.0 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.6 GO:1990246 uniplex complex(GO:1990246)
0.0 2.3 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.2 GO:0005921 gap junction(GO:0005921)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.5 GO:0005869 dynactin complex(GO:0005869)
0.0 1.5 GO:0031941 filamentous actin(GO:0031941)
0.0 2.6 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.7 GO:0032590 neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590)
0.0 0.9 GO:0070382 exocytic vesicle(GO:0070382)
0.0 2.7 GO:0030133 transport vesicle(GO:0030133)
0.0 1.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.5 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.6 GO:0008305 integrin complex(GO:0008305)
0.0 1.3 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0043186 P granule(GO:0043186)
0.0 0.1 GO:0000815 ESCRT III complex(GO:0000815)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 GO:0005499 vitamin D binding(GO:0005499)
0.9 2.6 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.6 2.9 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.5 3.6 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.5 2.0 GO:0005521 lamin binding(GO:0005521)
0.5 3.4 GO:0042936 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.4 2.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.4 1.8 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.4 2.8 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.3 2.3 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.2 1.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.2 1.8 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.2 2.9 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.2 0.6 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.2 2.1 GO:0004568 chitinase activity(GO:0004568)
0.2 4.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 3.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 0.9 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.2 1.0 GO:0008126 acetylesterase activity(GO:0008126)
0.2 1.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.4 GO:0031716 calcitonin receptor binding(GO:0031716)
0.1 0.7 GO:2001070 starch binding(GO:2001070)
0.1 1.0 GO:0005372 water transmembrane transporter activity(GO:0005372) water channel activity(GO:0015250)
0.1 0.4 GO:0019767 immunoglobulin receptor activity(GO:0019763) IgE receptor activity(GO:0019767)
0.1 2.0 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.6 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.7 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 2.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 5.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.9 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.1 1.3 GO:0016936 galactoside binding(GO:0016936)
0.1 1.7 GO:0005223 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 1.3 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.5 GO:0004133 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.1 2.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 3.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.3 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.1 1.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.9 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 1.9 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.4 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.9 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 1.8 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 1.1 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 0.4 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.1 0.4 GO:0002058 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.1 0.3 GO:0032038 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
0.1 1.3 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 2.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.3 GO:1990238 double-stranded DNA endodeoxyribonuclease activity(GO:1990238)
0.1 1.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.5 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1 0.3 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.1 0.4 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.1 0.7 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 1.1 GO:0042805 actinin binding(GO:0042805) muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.7 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.5 GO:0042287 MHC protein binding(GO:0042287)
0.0 1.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.0 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.7 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 2.2 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.1 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 1.8 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 2.0 GO:0044325 ion channel binding(GO:0044325)
0.0 1.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.4 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.5 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.8 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 1.1 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 1.9 GO:0005254 chloride channel activity(GO:0005254)
0.0 6.1 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.3 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 1.5 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 4.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 5.6 GO:0051015 actin filament binding(GO:0051015)
0.0 0.3 GO:0070122 isopeptidase activity(GO:0070122)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.0 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.4 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 0.7 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 1.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 1.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.5 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.3 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.6 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.1 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.5 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.7 2.1 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.6 5.6 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.3 2.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.2 4.6 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 1.8 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.1 0.7 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 1.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 2.1 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 0.8 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 0.7 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 0.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 0.8 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.4 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.4 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)