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PRJEB1986: zebrafish developmental stages transcriptome

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Results for mef2b

Z-value: 1.18

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Transcription factors associated with mef2b

Gene Symbol Gene ID Gene Info
ENSDARG00000093170 myocyte enhancer factor 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mef2bdr11_v1_chr22_+_18187857_181878570.361.3e-01Click!

Activity profile of mef2b motif

Sorted Z-values of mef2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_61205711 10.52 ENSDART00000055062
parvalbumin 1
chr5_+_51597677 7.06 ENSDART00000048210
ENSDART00000184797
creatine kinase, mitochondrial 2b (sarcomeric)
chr25_+_29160102 7.01 ENSDART00000162854
pyruvate kinase M1/2b
chr8_+_22930627 3.30 ENSDART00000187860
synaptophysin a
chr9_+_31795343 3.29 ENSDART00000139584
integrin, beta-like 1
chr10_-_22845485 3.25 ENSDART00000079454
vesicle-associated membrane protein 2
chr23_+_44614056 3.11 ENSDART00000188379
enolase 3, (beta, muscle)
chr6_-_14139503 3.08 ENSDART00000089577
calcium channel, voltage-dependent, beta 4b subunit
chr7_+_14291323 3.04 ENSDART00000053521
Rh family, C glycoprotein a
chr6_-_40722480 2.92 ENSDART00000188187
kelch repeat and BTB (POZ) domain containing 12
chr14_+_35901249 2.89 ENSDART00000105604
zgc:77938
chr20_-_26042070 2.88 ENSDART00000140255
si:dkey-12h9.6
chr5_-_72125551 2.87 ENSDART00000149412
SET and MYND domain containing 1a
chr20_-_26001288 2.84 ENSDART00000136518
ENSDART00000063177
calpain 3b
chr7_-_7420301 2.83 ENSDART00000102620
SIX homeobox 7
chr10_+_37145007 2.82 ENSDART00000131777
CUE domain containing 1a
chr1_+_8601935 2.79 ENSDART00000152367
si:ch211-160d14.6
chr17_-_12336987 2.78 ENSDART00000172001
synaptosomal-associated protein, 25b
chr6_-_40722200 2.70 ENSDART00000035101
kelch repeat and BTB (POZ) domain containing 12
chr11_+_11201096 2.66 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myomesin 2a
chr6_-_35472923 2.59 ENSDART00000185907
regulator of G protein signaling 8
chr3_-_32818607 2.58 ENSDART00000075465
myosin light chain, phosphorylatable, fast skeletal muscle a
chr25_-_29363934 2.44 ENSDART00000166889
neuroplastin a
chr13_+_9432501 2.43 ENSDART00000058064
zgc:123321
chr10_-_24371312 2.35 ENSDART00000149362
phosphatidylinositol transfer protein, alpha b
chr23_-_7826849 2.32 ENSDART00000157612
myelin transcription factor 1b
chr19_+_41169996 2.25 ENSDART00000048438
ankyrin repeat and SOCS box containing 4
chr23_-_32157865 2.22 ENSDART00000000876
nuclear receptor subfamily 4, group A, member 1
chr10_+_29698467 2.22 ENSDART00000163402
discs, large homolog 2 (Drosophila)
chr1_+_45080897 2.13 ENSDART00000129819
si:ch211-151p13.8
chr21_-_12272543 2.11 ENSDART00000081510
ENSDART00000151297
CUGBP, Elav-like family member 4
chr19_-_31035155 2.03 ENSDART00000161882
basic leucine zipper and W2 domains 2
chr2_+_1202347 1.95 ENSDART00000075837

chr21_+_11684830 1.93 ENSDART00000147473
proprotein convertase subtilisin/kexin type 1
chr19_-_31035325 1.93 ENSDART00000147504
basic leucine zipper and W2 domains 2
chr3_+_26135502 1.92 ENSDART00000146979
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr23_+_6077503 1.85 ENSDART00000081714
ENSDART00000139834
myosin binding protein Ha
chr7_-_27686021 1.85 ENSDART00000079112
ENSDART00000100989
calcitonin/calcitonin-related polypeptide, alpha
chr20_+_41549200 1.84 ENSDART00000135715
family with sequence similarity 184, member A
chr5_-_10946232 1.83 ENSDART00000163139
ENSDART00000031265
reticulon 4 receptor
chr3_+_23092762 1.80 ENSDART00000142884
ENSDART00000024136
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a
chr13_-_27767330 1.78 ENSDART00000131631
ENSDART00000112553
ENSDART00000189911
regulating synaptic membrane exocytosis 1a
chr2_-_4787566 1.76 ENSDART00000160663
ENSDART00000157808
tyrosine kinase, non-receptor, 2b
chr21_+_11685009 1.76 ENSDART00000014668
proprotein convertase subtilisin/kexin type 1
chr25_-_13381854 1.74 ENSDART00000164621
ENSDART00000169129
NDRG family member 4
chr18_+_7264961 1.74 ENSDART00000188461

chr20_+_34455645 1.70 ENSDART00000135789
methyltransferase like 11B
chr21_-_27185915 1.67 ENSDART00000135052
solute carrier family 8 (sodium/calcium exchanger), member 4a
chr21_+_12010505 1.63 ENSDART00000123522
aquaporin 7
chr23_-_38497705 1.57 ENSDART00000109493
teashirt zinc finger homeobox 2
chr23_+_20687340 1.56 ENSDART00000143503
ubiquitin specific peptidase 21
chr25_+_3677650 1.51 ENSDART00000154348
prion protein, related sequence 3
chr23_+_22658700 1.50 ENSDART00000192248
enolase 1a, (alpha)
chr4_-_23908802 1.47 ENSDART00000138873
cugbp, Elav-like family member 2
chr3_-_49504023 1.43 ENSDART00000168108
protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a
chr12_-_34035364 1.41 ENSDART00000087065
TIMP metallopeptidase inhibitor 2a
chr6_-_10780698 1.41 ENSDART00000151714
G protein-coupled receptor 155b
chr5_-_51819027 1.35 ENSDART00000164267
homer scaffolding protein 1b
chr10_-_2522588 1.34 ENSDART00000081926

chr21_-_25669820 1.34 ENSDART00000148236
transmembrane protein 179B
chr9_-_52814204 1.30 ENSDART00000140771
ENSDART00000007401
si:ch211-45c16.2
chr16_+_29663809 1.25 ENSDART00000191336
tropomodulin 4 (muscle)
chr1_-_21483832 1.23 ENSDART00000102790
glycine receptor, beta a
chr13_+_47710434 1.20 ENSDART00000188724
transmembrane protein 87B
chr24_-_20444844 1.18 ENSDART00000048940
villin-like
chr17_-_50234004 1.12 ENSDART00000058706
v-fos FBJ murine osteosarcoma viral oncogene homolog Aa
chr19_-_8096984 1.12 ENSDART00000146987
si:dkey-266f7.9
chr14_+_24215046 1.09 ENSDART00000079215
stanniocalcin 2a
chr4_+_77060861 1.07 ENSDART00000174271
ENSDART00000174393
ENSDART00000150450
si:dkey-240n22.8
chr1_+_19708508 1.05 ENSDART00000054581
ENSDART00000131206
membrane-associated ring finger (C3HC4) 1
chr14_-_7245971 1.04 ENSDART00000108796
storkhead box 2b
chr6_-_46403475 0.99 ENSDART00000154148
calcium/calmodulin-dependent protein kinase Ia
chr7_+_33457148 0.98 ENSDART00000133562
ENSDART00000074587
progestin and adipoQ receptor family member Vb
chr15_+_20543770 0.98 ENSDART00000092357
small G protein signaling modulator 2
chr16_-_17188294 0.95 ENSDART00000165883
opsin 9
chr13_-_37647209 0.91 ENSDART00000189102
si:dkey-188i13.10
chr23_+_20110086 0.91 ENSDART00000054664
troponin C type 1b (slow)
chr12_+_41697664 0.90 ENSDART00000162302
BCL2 interacting protein 3
chr14_-_32405387 0.87 ENSDART00000184647
fibroblast growth factor 13a
chr16_+_25245857 0.87 ENSDART00000155220
kelch-like family member 38b
chr23_+_3721042 0.87 ENSDART00000143323
small integral membrane protein 29
chr4_+_5180650 0.86 ENSDART00000067390
fibroblast growth factor 6b
chr9_-_23891102 0.82 ENSDART00000186799
ankyrin repeat and SOCS box containing 18
chr17_-_10025234 0.80 ENSDART00000008355
cofilin 2 (muscle)
chr17_+_45648836 0.78 ENSDART00000155037
zgc:162184
chr7_-_31938938 0.78 ENSDART00000132353
brain-derived neurotrophic factor
chr8_+_17987215 0.77 ENSDART00000113605
leucine-rich repeats and IQ motif containing 3
chr21_+_43559123 0.76 ENSDART00000151212
G protein-coupled receptor 185 a
chr13_-_12667220 0.75 ENSDART00000079594
family with sequence similarity 241 member A
chr11_-_26701611 0.74 ENSDART00000083010
acyl-CoA dehydrogenase family, member 9
chr19_-_7321221 0.72 ENSDART00000092375
oxidation resistance 1b
chr5_+_16580739 0.69 ENSDART00000135140
5-hydroxytryptamine (serotonin) receptor 7c
chr25_-_29988352 0.68 ENSDART00000067059
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5b
chr10_-_41450367 0.68 ENSDART00000122682
ENSDART00000189549
calcium binding protein 1b
chr9_-_23894392 0.67 ENSDART00000133417
ankyrin repeat and SOCS box containing 18
chr8_+_4337312 0.66 ENSDART00000182228
myosin, light chain 2b, regulatory, cardiac, slow
chr4_-_5863906 0.66 ENSDART00000169424
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
chr12_+_8373525 0.66 ENSDART00000152180
AT-rich interaction domain 5B
chr5_-_30151815 0.61 ENSDART00000156048
zinc finger and BTB domain containing 44
chr9_+_32178050 0.60 ENSDART00000169526
coenzyme Q10B
chr24_-_7777389 0.59 ENSDART00000138541
RPGR interacting protein 1
chr8_-_53166975 0.59 ENSDART00000114683
rabenosyn, RAB effector
chr23_-_25050329 0.56 ENSDART00000140216
arginine vasopressin receptor 2a, duplicate a
chr8_+_44420108 0.56 ENSDART00000075381

chr10_-_17501528 0.55 ENSDART00000144847
solute carrier family 2 (facilitated glucose transporter), member 11-like
chr25_-_12809361 0.52 ENSDART00000162750
carbonic anhydrase Va
chr10_-_8033468 0.51 ENSDART00000140476
ATPase H+ transporting V0 subunit a2a
chr15_-_36347858 0.50 ENSDART00000155274
ENSDART00000157936
si:dkey-23k10.2
chr9_-_28399071 0.50 ENSDART00000104317
ENSDART00000064343
Kruppel-like factor 7b
chr7_+_50464500 0.47 ENSDART00000191356
serine incorporator 4
chr5_+_64842730 0.47 ENSDART00000144732
leucine rich repeat containing 8 VRAC subunit Ab
chr10_-_2527342 0.46 ENSDART00000184168

chr1_-_58592866 0.46 ENSDART00000161039
adhesion G protein-coupled receptor E5b, duplicate 2
chr11_-_1948784 0.46 ENSDART00000082475
nuclear receptor subfamily 1, group D, member 4b
chr15_-_14552101 0.46 ENSDART00000171169
numb homolog (Drosophila)-like
chr7_-_48263516 0.46 ENSDART00000006619
ENSDART00000142370
ENSDART00000148273
ENSDART00000147968
RNA binding protein with multiple splicing 2b
chr3_-_18189283 0.46 ENSDART00000049240
transducer of ERBB2, 1a
chr3_-_13946446 0.45 ENSDART00000171249
glutaryl-CoA dehydrogenase b
chr3_+_32425202 0.44 ENSDART00000156464
proline rich 12b
chr21_+_40589770 0.42 ENSDART00000164650
ENSDART00000161584
ENSDART00000161108
pyruvate dehydrogenase kinase, isozyme 3b
chr10_+_29259882 0.41 ENSDART00000180606
synaptotagmin-like 2a
chr22_+_38310957 0.40 ENSDART00000040550
Tnf receptor-associated factor 5
chr16_-_17200120 0.38 ENSDART00000147739
glyceraldehyde-3-phosphate dehydrogenase
chr9_-_33107237 0.37 ENSDART00000013918
calsequestrin 2
chr25_+_35212919 0.37 ENSDART00000180127
anoctamin 5a
chr8_+_30456161 0.36 ENSDART00000085894
phosphoglucomutase 5
chr7_+_39006837 0.35 ENSDART00000173735
diacylglycerol kinase, zeta a
chr19_+_24394560 0.33 ENSDART00000142506
si:dkey-81h8.1
chr11_-_34478225 0.32 ENSDART00000189604
xyloside xylosyltransferase 1
chr17_-_50233493 0.32 ENSDART00000172266
v-fos FBJ murine osteosarcoma viral oncogene homolog Aa
chr2_+_37975026 0.31 ENSDART00000034802
si:rp71-1g18.13
chr22_-_20259309 0.30 ENSDART00000139160
si:dkey-110c1.10
chr11_-_18601955 0.29 ENSDART00000180565
zinc finger, MYND-type containing 8
chr9_-_48937240 0.29 ENSDART00000075627
ceramide synthase 6
chr1_-_45662774 0.28 ENSDART00000042158
serine hydrolase-like
chr10_+_29260096 0.23 ENSDART00000088973
synaptotagmin-like 2a
chr1_-_6494384 0.23 ENSDART00000109356
Kruppel-like factor 7a
chr17_-_13026634 0.23 ENSDART00000113713
family with sequence similarity 177, member A1
chr5_-_31926906 0.22 ENSDART00000187340
slingshot protein phosphatase 1b
chr24_+_8904135 0.22 ENSDART00000066782
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr6_+_43353271 0.21 ENSDART00000191775

chr24_+_26088143 0.19 ENSDART00000171129

chr23_-_3721444 0.19 ENSDART00000141682
nudix (nucleoside diphosphate linked moiety X)-type motif 3a
chr5_-_18911114 0.19 ENSDART00000014434
bri3 binding protein
chr16_-_16225260 0.18 ENSDART00000165790
granulito
chr7_-_52334840 0.18 ENSDART00000174173

chr4_+_14343706 0.17 ENSDART00000142845
prolactin 2
chr17_+_1992495 0.16 ENSDART00000192937

chr2_-_37353098 0.13 ENSDART00000056522
SKI-like proto-oncogene a
chr6_+_36942966 0.13 ENSDART00000028895
neuronal growth regulator 1
chr6_-_42003780 0.13 ENSDART00000032527
caveolin 3
chr10_-_8032885 0.12 ENSDART00000188619
ATPase H+ transporting V0 subunit a2a
chr5_-_25236340 0.11 ENSDART00000162774
ATP-binding cassette, sub-family A (ABC1), member 2
chr2_-_6182098 0.10 ENSDART00000156167
si:ch73-182a11.2
chr19_-_14155781 0.09 ENSDART00000169232
nuclear receptor subfamily 0, group B, member 2b
chr24_-_28333029 0.08 ENSDART00000149015
ENSDART00000129174
protein kinase, AMP-activated, gamma 2 non-catalytic subunit a
chr6_-_6248893 0.07 ENSDART00000124662
reticulon 4a
chr19_-_41069573 0.06 ENSDART00000111982
ENSDART00000193142
sarcoglycan, epsilon
chr4_-_13509946 0.04 ENSDART00000134720
interferon, gamma 1-2
chr20_-_7000225 0.04 ENSDART00000100098
adenylate cyclase 1a
chr20_-_24443680 0.03 ENSDART00000191337

chr11_+_29965822 0.03 ENSDART00000127049
interleukin-1 family member A
chr6_-_46768040 0.02 ENSDART00000154071
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 2
chr5_+_61657702 0.02 ENSDART00000134387
ENSDART00000171248
adaptor-related protein complex 2, beta 1 subunit
chr6_+_51713076 0.01 ENSDART00000146281
RIPOR family member 3
chr13_+_42011287 0.01 ENSDART00000131147
cytochrome P450, family 1, subfamily B, polypeptide 1
chr10_+_8688678 0.01 ENSDART00000147568
si:dkey-27b3.4
chr3_+_17456428 0.01 ENSDART00000090676
ENSDART00000182082
si:ch211-210g13.5

Network of associatons between targets according to the STRING database.

First level regulatory network of mef2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0097264 self proteolysis(GO:0097264)
0.6 2.6 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.6 2.3 GO:0003322 pancreatic A cell development(GO:0003322)
0.6 2.9 GO:0023041 neuronal signal transduction(GO:0023041)
0.6 4.6 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.6 1.7 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.5 7.1 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.5 1.9 GO:0031446 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.4 2.9 GO:0046292 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.4 3.0 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.3 4.5 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.3 1.5 GO:0021731 trigeminal motor nucleus development(GO:0021731)
0.3 0.8 GO:0030043 actin filament fragmentation(GO:0030043)
0.3 1.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.3 2.9 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.2 2.2 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.2 3.7 GO:0016486 peptide hormone processing(GO:0016486)
0.2 1.4 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.2 3.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.2 1.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.2 2.8 GO:1901642 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.2 2.8 GO:0046549 retinal cone cell development(GO:0046549)
0.2 1.4 GO:0071326 cellular response to carbohydrate stimulus(GO:0071322) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.2 1.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 1.7 GO:0042044 fluid transport(GO:0042044)
0.1 7.2 GO:0006096 glycolytic process(GO:0006096)
0.1 2.1 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 3.3 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.1 2.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 0.9 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 0.4 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.1 0.5 GO:0051148 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
0.1 2.4 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 1.9 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 1.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 1.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 3.1 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 1.6 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.1 0.7 GO:0060612 adipose tissue development(GO:0060612)
0.1 0.8 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.5 GO:0021634 optic nerve formation(GO:0021634)
0.1 0.9 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 1.9 GO:0055064 chloride ion homeostasis(GO:0055064)
0.1 0.6 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.5 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.6 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.6 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 1.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 1.2 GO:0051014 actin filament severing(GO:0051014)
0.0 0.2 GO:1901909 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 2.4 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.9 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.4 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.1 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.2 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.9 GO:0007602 phototransduction(GO:0007602)
0.0 0.7 GO:0015908 fatty acid transport(GO:0015908)
0.0 2.1 GO:0006936 muscle contraction(GO:0006936)
0.0 0.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 1.0 GO:0048477 oogenesis(GO:0048477)
0.0 0.8 GO:0006006 glucose metabolic process(GO:0006006)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.5 1.9 GO:0031673 H zone(GO:0031673)
0.5 2.8 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.3 5.3 GO:0031430 M band(GO:0031430)
0.1 2.6 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 1.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 2.9 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 1.8 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 3.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 2.2 GO:0031594 neuromuscular junction(GO:0031594)
0.1 3.3 GO:0008305 integrin complex(GO:0008305)
0.1 0.6 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 5.1 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 3.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 2.2 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 2.2 GO:0042383 sarcolemma(GO:0042383)
0.0 2.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.9 GO:0030426 growth cone(GO:0030426)
0.0 1.0 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.4 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 1.3 GO:0014069 postsynaptic density(GO:0014069)
0.0 3.8 GO:0030133 transport vesicle(GO:0030133)
0.0 2.3 GO:0030424 axon(GO:0030424)
0.0 3.6 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 7.0 GO:0004743 pyruvate kinase activity(GO:0004743)
0.6 1.9 GO:0031716 calcitonin receptor binding(GO:0031716)
0.6 2.9 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024) S-(hydroxymethyl)glutathione dehydrogenase activity(GO:0051903)
0.6 4.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.6 1.7 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.5 7.1 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.3 2.8 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.3 2.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.3 1.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.3 1.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.2 0.7 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.2 9.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 1.6 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.2 2.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 3.0 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 1.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 1.7 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 3.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.8 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.5 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.1 1.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 3.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.3 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.1 0.4 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 1.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 2.4 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 0.8 GO:0005165 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.1 1.3 GO:0005523 tropomyosin binding(GO:0005523)
0.1 3.3 GO:0005178 integrin binding(GO:0005178)
0.1 0.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.6 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.3 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.0 0.6 GO:0051117 ATPase binding(GO:0051117)
0.0 0.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 2.9 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.2 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 1.0 GO:0042287 MHC protein binding(GO:0042287)
0.0 1.9 GO:0044325 ion channel binding(GO:0044325)
0.0 0.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.4 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 1.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.0 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.9 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.7 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.0 3.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 13.4 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.6 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 3.6 GO:0051015 actin filament binding(GO:0051015)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 2.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 2.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.4 ST JNK MAPK PATHWAY JNK MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.5 1.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.4 3.7 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.2 3.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 2.2 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 0.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 2.6 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.7 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 2.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation