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PRJEB1986: zebrafish developmental stages transcriptome

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Results for mecp2

Z-value: 1.70

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Transcription factors associated with mecp2

Gene Symbol Gene ID Gene Info
ENSDARG00000014218 methyl CpG binding protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mecp2dr11_v1_chr8_-_7637626_76376400.624.5e-03Click!

Activity profile of mecp2 motif

Sorted Z-values of mecp2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_68563862 8.09 ENSDART00000182970

chr4_-_77557279 7.92 ENSDART00000180113

chr4_-_68564988 7.11 ENSDART00000191212

chr5_-_825920 5.24 ENSDART00000126982
zgc:158463
chr3_+_31396149 2.98 ENSDART00000151423
ENSDART00000193580
complement component 1, q subcomponent-like 3b
chr11_+_39969048 2.75 ENSDART00000193693
period circadian clock 3
chr19_-_11846958 2.66 ENSDART00000148516
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr19_-_47587719 2.58 ENSDART00000111108

chr9_-_32158288 2.55 ENSDART00000037182
ankyrin repeat domain 44
chr4_-_77561679 2.53 ENSDART00000180809

chr23_+_40908583 2.46 ENSDART00000180933

chr5_-_13685047 2.38 ENSDART00000018351
zgc:65851
chr4_+_55758103 2.27 ENSDART00000185964

chr10_-_36633882 2.27 ENSDART00000077161
ENSDART00000137688
remodeling and spacing factor 1b, tandem duplicate 1
remodeling and spacing factor 1b, tandem duplicate 1
chr20_+_32523576 2.22 ENSDART00000147319
Scm polycomb group protein like 4
chr19_-_6988837 2.21 ENSDART00000145741
ENSDART00000167640
zinc finger protein 384 like
chr20_-_45661049 2.16 ENSDART00000124582
ENSDART00000131251
N-ethylmaleimide-sensitive factor attachment protein, beta b
chr11_-_37589293 2.09 ENSDART00000172989
bassoon (presynaptic cytomatrix protein) b
chr10_-_9115383 2.06 ENSDART00000139324
si:dkeyp-41f9.3
chr19_-_677713 2.06 ENSDART00000025146
solute carrier family 6 (neutral amino acid transporter), member 19a, tandem duplicate 1
chr3_+_22059066 2.06 ENSDART00000155739
KAT8 regulatory NSL complex subunit 1b
chr19_+_232536 2.04 ENSDART00000137880
synaptic Ras GTPase activating protein 1a
chr15_-_18138607 2.03 ENSDART00000176690

chr10_-_2682198 1.99 ENSDART00000183727
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr16_+_34528409 1.96 ENSDART00000144718
progestin and adipoQ receptor family member VII, b
chr9_+_56422311 1.90 ENSDART00000171958
G protein-coupled receptor 39
chr13_+_51853716 1.89 ENSDART00000175341
ENSDART00000187855

chr8_-_4327473 1.89 ENSDART00000134378
cut-like homeobox 2b
chr6_+_41554794 1.88 ENSDART00000165424
SLIT-ROBO Rho GTPase activating protein 3
chr8_+_48966165 1.86 ENSDART00000165425
AP2 associated kinase 1a
chr20_-_52939501 1.85 ENSDART00000166508
farnesyl-diphosphate farnesyltransferase 1
chr2_-_50372467 1.85 ENSDART00000108900
contactin associated protein like 2b
chr17_-_6759006 1.82 ENSDART00000184692
ENSDART00000180530
visinin-like 1b
chr4_+_3438510 1.77 ENSDART00000155320
ataxin 7-like 1
chr14_-_2355833 1.75 ENSDART00000157677
si:ch73-233f7.6
chr4_+_23223881 1.73 ENSDART00000133056
ENSDART00000089126
thyrotropin releasing hormone degrading enzyme, tandem duplicate 1
chr12_+_22680115 1.73 ENSDART00000152879
actin binding LIM protein family, member 2
chr21_-_10446405 1.72 ENSDART00000167948
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr4_-_1360495 1.69 ENSDART00000164623
pleiotrophin
chr12_+_33038757 1.68 ENSDART00000153146
RNA binding fox-1 homolog 3a
chr10_+_41668483 1.66 ENSDART00000127073
leucine rich repeat containing 75Bb
chr1_-_54706039 1.66 ENSDART00000083633
exosome component 1
chr8_+_48965767 1.63 ENSDART00000008058
AP2 associated kinase 1a
chr17_+_389218 1.62 ENSDART00000162898
si:rp71-62i8.1
chr15_-_30816370 1.57 ENSDART00000142982
ENSDART00000050649
ENSDART00000136901
ENSDART00000100194
musashi RNA-binding protein 2b
chr19_+_41479990 1.57 ENSDART00000087187
argonaute RISC catalytic component 2
chr3_+_14463941 1.56 ENSDART00000170927
calponin 1, basic, smooth muscle, b
chr3_-_27880229 1.55 ENSDART00000151404
4-aminobutyrate aminotransferase
chr21_-_8513192 1.54 ENSDART00000084378
crumbs family member 2a
chr21_-_2814709 1.54 ENSDART00000097664
semaphorin 4D
chr14_-_2050057 1.51 ENSDART00000112875
protocadherin beta 15
chr15_-_37921998 1.48 ENSDART00000193597
ENSDART00000181443
ENSDART00000168790
si:dkey-238d18.5
chr25_-_35145920 1.46 ENSDART00000157137
si:dkey-261m9.19
chr9_+_17787864 1.45 ENSDART00000013111
diacylglycerol kinase, eta
chr19_-_9503473 1.45 ENSDART00000091615
intermediate filament family orphan 1a
chr6_-_21988375 1.44 ENSDART00000161257
plexin b1b
chr15_+_2559875 1.44 ENSDART00000178505
SH2B adaptor protein 2
chr17_+_52300018 1.43 ENSDART00000190302
estrogen-related receptor beta
chr9_-_55790458 1.43 ENSDART00000161247
sosondowah ankyrin repeat domain family Ca
chr17_-_11418513 1.42 ENSDART00000064412
ENSDART00000151847
AT rich interactive domain 4A (RBP1-like)
chr25_+_8063455 1.41 ENSDART00000073919
potassium voltage-gated channel, Shaw-related subfamily, member 1b
chr6_+_57741039 1.41 ENSDART00000169175
syntrophin alpha 1
chr10_-_44981295 1.41 ENSDART00000166528
purine-rich element binding protein Bb
chr15_+_28685625 1.41 ENSDART00000188797
ENSDART00000166036
neuro-oncological ventral antigen 2
chr20_-_24122881 1.39 ENSDART00000131857
BTB and CNC homology 1, basic leucine zipper transcription factor 2b
chr19_+_48372446 1.39 ENSDART00000161466
abhydrolase domain containing 5b
chr20_+_4060839 1.39 ENSDART00000178565
tripartite motif containing 67
chr13_-_31166544 1.38 ENSDART00000146250
ENSDART00000132129
ENSDART00000139591
mitogen-activated protein kinase 8a
chr23_+_2361184 1.38 ENSDART00000184469

chr6_+_58406014 1.37 ENSDART00000044241
potassium voltage-gated channel, KQT-like subfamily, member 2b
chr4_-_12102025 1.36 ENSDART00000048391
ENSDART00000023894
B-Raf proto-oncogene, serine/threonine kinase
chr4_+_20263097 1.35 ENSDART00000138820
leucine-rich repeats and transmembrane domains 2a
chr5_+_22633188 1.33 ENSDART00000128781
melatonin receptor 1C
chr9_-_135774 1.33 ENSDART00000160435

chr22_+_15331214 1.33 ENSDART00000136566
sulfotransferase family 3, cytosolic sulfotransferase 4
chr18_-_46881108 1.32 ENSDART00000190084
GRAM domain containing 1Bb
chr15_+_30158652 1.31 ENSDART00000190682
nemo-like kinase, type 2
chr8_+_2757821 1.30 ENSDART00000051403
ENSDART00000160551
SH3-domain GRB2-like endophilin B2a
chr19_+_3056450 1.30 ENSDART00000141324
ENSDART00000082353
heat shock transcription factor 1
chr3_+_48842918 1.29 ENSDART00000159420
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1a
chr11_+_19781053 1.29 ENSDART00000029680
ENSDART00000182743
Ca2+-dependent activator protein for secretion a
chr21_-_42100471 1.28 ENSDART00000166148
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr3_-_25054002 1.28 ENSDART00000086768
E1A binding protein p300 b
chr16_-_13388821 1.28 ENSDART00000144062
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b
chr23_-_44677315 1.20 ENSDART00000143054
kinesin family member 1C
chr8_-_3773374 1.18 ENSDART00000115036
BICD family like cargo adaptor 1
chr20_+_52389858 1.18 ENSDART00000185863
ENSDART00000166651
Rho GTPase activating protein 39
chr18_-_1143996 1.17 ENSDART00000189186
ENSDART00000136140
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr7_+_1534820 1.16 ENSDART00000192997
TOX high mobility group box family member 4 b
chr11_-_38510469 1.16 ENSDART00000162305
si:ch211-117k10.3
chr17_+_43629008 1.15 ENSDART00000184185
ENSDART00000181681
zinc finger protein 365
chr10_-_33156789 1.15 ENSDART00000192268
ENSDART00000182065
ENSDART00000081170
cut-like homeobox 1a
chr23_-_27694960 1.15 ENSDART00000135129
si:dkey-166n8.9
chr20_+_474288 1.14 ENSDART00000026794
5'-nucleotidase domain containing 1
chr16_-_52966811 1.14 ENSDART00000153758
ENSDART00000009256
bromodomain containing 9
chr21_+_45626136 1.11 ENSDART00000158742
interferon regulatory factor 1b
chr9_+_56422517 1.11 ENSDART00000168620
G protein-coupled receptor 39
chr5_+_69950882 1.11 ENSDART00000097359
DnaJ (Hsp40) homolog, subfamily C , member 25
chr8_+_29963024 1.10 ENSDART00000149372
patched 1
chr14_+_35024521 1.09 ENSDART00000158634
ENSDART00000170631
early B cell factor 3a
chr21_+_10021823 1.08 ENSDART00000163995
hect domain and RLD 7
chr18_+_29403017 1.08 ENSDART00000176966
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog a (paralog a)
chr5_-_24712405 1.07 ENSDART00000033630
si:ch211-106a19.1
chr15_+_44093286 1.06 ENSDART00000114352
zgc:112998
chr14_-_2196267 1.06 ENSDART00000161674
ENSDART00000125674
protocadherin 2 alpha b 8
protocadherin 2 alpha b 9
chr17_-_27235797 1.05 ENSDART00000130080
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr1_+_52632856 1.05 ENSDART00000011725
solute carrier family 44 (choline transporter), member 1a
chr6_-_59271270 1.04 ENSDART00000126870
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2b
chr1_-_18446161 1.04 ENSDART00000089442
kelch-like family member 5
chr15_+_45595385 1.04 ENSDART00000161937
ENSDART00000170214
ENSDART00000157450
ATG16 autophagy related 16-like 1 (S. cerevisiae)
chr5_-_37247654 1.04 ENSDART00000112312
leucine-rich repeats and calponin homology (CH) domain containing 2
chr22_-_38607504 1.04 ENSDART00000164609
si:ch211-126j24.1
chr2_-_2642476 1.03 ENSDART00000124032
SERPINE1 mRNA binding protein 1b
chr9_+_27411502 1.02 ENSDART00000143994
si:dkey-193n17.9
chr6_-_607063 1.01 ENSDART00000189900
lectin, galactoside-binding, soluble, 2b
chr18_+_50961953 1.00 ENSDART00000158768
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
chr15_+_45994123 1.00 ENSDART00000124704
leucine rich repeat and fibronectin type III domain containing 1
chr13_-_301309 1.00 ENSDART00000131747
chitin synthase 1
chr3_+_17806213 0.99 ENSDART00000055890
zinc finger protein 385C
chr5_+_45140914 0.99 ENSDART00000172702
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr9_+_30585552 0.99 ENSDART00000160590
ENSDART00000189815
ENSDART00000143766
TBC1 domain family, member 4
chr9_+_24159725 0.98 ENSDART00000137756
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2a
chr20_+_715739 0.97 ENSDART00000136768
myosin VIa
chr25_+_3994823 0.97 ENSDART00000154020
EPS8 like 2
chr21_-_45891262 0.95 ENSDART00000169816
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr15_+_31471808 0.95 ENSDART00000110078
odorant receptor, family C, subfamily 102, member 3
chr6_+_58915889 0.94 ENSDART00000083628
DNA-damage-inducible transcript 3
chr21_+_8427059 0.94 ENSDART00000143151
DENN/MADD domain containing 1A
chr6_-_36795111 0.94 ENSDART00000160669
ENSDART00000104256
ENSDART00000187751
ENSDART00000161928
ENSDART00000183264
optic atrophy 1 (autosomal dominant)
chr3_+_13637383 0.94 ENSDART00000166000
si:ch211-194b1.1
chr18_+_28564640 0.94 ENSDART00000016983
spondin 1a
chr4_+_121709 0.94 ENSDART00000186461
ENSDART00000172255
cAMP responsive element binding protein-like 2
chr7_+_1442059 0.93 ENSDART00000173391
si:cabz01090193.1
chr5_+_15992655 0.90 ENSDART00000182148
zinc and ring finger 3
chr1_-_23370395 0.90 ENSDART00000143014
ENSDART00000126785
ENSDART00000159138
PDS5 cohesin associated factor A
chr18_+_507835 0.89 ENSDART00000189701
neural precursor cell expressed, developmentally down-regulated 4a
chr18_+_45228691 0.88 ENSDART00000127953
LARGE xylosyl- and glucuronyltransferase 2
chr11_+_45436703 0.88 ENSDART00000168295
ENSDART00000173293
son of sevenless homolog 1 (Drosophila)
chr5_-_19861766 0.88 ENSDART00000088904
glycolipid transfer protein a
chr9_-_52206336 0.88 ENSDART00000114222
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1b
chr24_+_792429 0.88 ENSDART00000082523
inositol(myo)-1(or 4)-monophosphatase 2
chr25_+_4581214 0.88 ENSDART00000185552

chr5_-_29488245 0.87 ENSDART00000047719
ENSDART00000141154
ENSDART00000171165
calcium channel, voltage-dependent, N type, alpha 1B subunit, a
chr18_-_16590056 0.87 ENSDART00000143744
mgat4 family, member C
chr24_-_33276139 0.87 ENSDART00000128943
nuclear receptor binding protein 2b
chr13_-_40120252 0.87 ENSDART00000157852
cartilage acidic protein 1b
chr3_+_58655375 0.86 ENSDART00000186908

chr15_-_47895200 0.85 ENSDART00000027060
zmp:0000000529
chr13_+_681628 0.84 ENSDART00000016604
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr16_+_68069 0.84 ENSDART00000185385
ENSDART00000159652
SRY (sex determining region Y)-box 4b
chr6_-_57722816 0.83 ENSDART00000186163
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr6_+_39222598 0.83 ENSDART00000154991
beta-1,4-N-acetyl-galactosaminyl transferase 1b
chr8_+_29962635 0.83 ENSDART00000007640
patched 1
chr20_+_52458765 0.83 ENSDART00000057980
tissue specific transplantation antigen P35B
chr12_+_28749189 0.82 ENSDART00000013980
T-box 21
chr2_+_39108339 0.82 ENSDART00000085675
calsyntenin 2
chr3_+_35005062 0.81 ENSDART00000181163
protein kinase C, beta b
chr12_-_18961289 0.81 ENSDART00000168405
E1A binding protein p300 a
chr17_+_22587356 0.81 ENSDART00000157328
baculoviral IAP repeat containing 6
chr12_-_3705862 0.81 ENSDART00000193864
ENSDART00000185857

chr8_-_22739757 0.81 ENSDART00000182167
ENSDART00000171891
IQ motif and Sec7 domain 2a
chr2_-_5399437 0.81 ENSDART00000132411
si:ch1073-184j22.2
chr10_+_44042033 0.81 ENSDART00000190006
ENSDART00000046172
crystallin, beta A4
chr10_-_41156348 0.80 ENSDART00000058622
AP2 associated kinase 1b
chr10_-_22845485 0.80 ENSDART00000079454
vesicle-associated membrane protein 2
chr7_-_33921366 0.80 ENSDART00000052397
protein inhibitor of activated STAT, 1a
chr13_-_36525982 0.77 ENSDART00000114744
phosphofurin acidic cluster sorting protein 2
chr19_+_9032073 0.77 ENSDART00000127755
ash1 (absent, small, or homeotic)-like (Drosophila)
chr6_-_59271436 0.77 ENSDART00000174588
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2b
chr12_+_25845494 0.76 ENSDART00000170582
glutamate dehydrogenase 1b
chr2_-_32501501 0.76 ENSDART00000181309
Fas apoptotic inhibitory molecule 2a
chr22_-_13544244 0.76 ENSDART00000110136
contactin associated protein-like 5b
chr16_-_2807527 0.76 ENSDART00000148927
transforming growth factor, beta 2
chr5_-_49012569 0.75 ENSDART00000184690
si:dkey-172m14.2
chr18_-_399554 0.75 ENSDART00000164374
ENSDART00000186311
ENSDART00000181816
ENSDART00000181892
si:ch211-79l17.1
chr10_-_43392667 0.75 ENSDART00000183033
EGF-like repeats and discoidin I-like domains 3b
chr15_+_23208042 0.75 ENSDART00000006085
Cbl proto-oncogene, E3 ubiquitin protein ligase
chr5_+_22791686 0.74 ENSDART00000014806
neuronal PAS domain protein 2
chr1_+_38858399 0.74 ENSDART00000165454

chr1_-_53407448 0.74 ENSDART00000160033
ENSDART00000172322
ELMO/CED-12 domain containing 2
chr1_-_23557877 0.73 ENSDART00000145942
family with sequence similarity 184, member B
chr2_+_24507597 0.72 ENSDART00000133109
ribosomal protein S28
chr9_+_1505206 0.72 ENSDART00000093427
ENSDART00000137230
phosphodiesterase 11a
chr18_+_50461981 0.72 ENSDART00000158761

chr10_+_34377697 0.71 ENSDART00000189441
StAR-related lipid transfer (START) domain containing 13a
chr11_+_2687395 0.70 ENSDART00000082510
UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6
chr21_-_13751535 0.69 ENSDART00000111666
neural proliferation, differentiation and control, 1a
chr7_+_9922607 0.67 ENSDART00000184532
ENSDART00000113396
ceramide synthase 3a
chr13_-_51922290 0.66 ENSDART00000168648
serum response factor b
chr5_+_26079178 0.66 ENSDART00000145920
si:dkey-201c13.2
chr10_+_39476600 0.65 ENSDART00000135756
kirre like nephrin family adhesion molecule 3a
chr1_+_31864404 0.64 ENSDART00000075260
internexin neuronal intermediate filament protein, alpha b
chr3_-_39627412 0.64 ENSDART00000123292
si:dkey-27o4.1
chr8_+_50190742 0.64 ENSDART00000099863
solute carrier family 25 (mitochondrial iron transporter), member 37
chr24_-_20808283 0.64 ENSDART00000143759
vasoactive intestinal peptide receptor 1b
chr25_+_35067318 0.64 ENSDART00000186828

chr19_+_43822968 0.64 ENSDART00000171041
elongin A
chr13_+_14006118 0.63 ENSDART00000131875
ENSDART00000089528
attractin
chr17_-_5860222 0.62 ENSDART00000058894
si:ch73-340m8.2
chr4_-_789645 0.61 ENSDART00000164441
microtubule-associated protein, RP/EB family, member 3b

Network of associatons between targets according to the STRING database.

First level regulatory network of mecp2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.5 2.2 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.5 2.0 GO:0006114 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.4 1.8 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.3 1.4 GO:0010896 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.3 1.6 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.3 1.6 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.3 0.9 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.3 1.2 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.3 1.3 GO:0070208 protein heterotrimerization(GO:0070208)
0.3 4.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.2 1.0 GO:0031507 heterochromatin assembly(GO:0031507)
0.2 0.9 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.2 0.9 GO:0046324 positive regulation of fat cell differentiation(GO:0045600) regulation of glucose import(GO:0046324)
0.2 1.8 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.2 0.9 GO:0032801 receptor catabolic process(GO:0032801)
0.2 1.9 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.2 2.1 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.2 1.0 GO:0019079 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.2 1.0 GO:1901073 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.2 0.6 GO:0022009 central nervous system vasculogenesis(GO:0022009)
0.2 0.6 GO:0034035 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.2 0.6 GO:0045218 zonula adherens maintenance(GO:0045218)
0.2 0.5 GO:0097095 frontonasal suture morphogenesis(GO:0097095)
0.2 1.0 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.2 1.7 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.2 0.5 GO:0008344 adult locomotory behavior(GO:0008344)
0.1 0.7 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.1 0.4 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 2.7 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 0.7 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 1.0 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.1 0.8 GO:0098815 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 0.8 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.1 1.7 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.1 0.9 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.1 1.2 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.1 1.3 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 0.5 GO:0097272 ammonia homeostasis(GO:0097272)
0.1 1.0 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.1 0.4 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.5 GO:0007618 mating(GO:0007618)
0.1 0.6 GO:1901490 protein kinase D signaling(GO:0089700) regulation of lymphangiogenesis(GO:1901490)
0.1 0.6 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.1 0.3 GO:0048660 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.1 0.4 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 1.8 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 0.6 GO:0071623 negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.1 2.6 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 1.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.8 GO:0061056 sclerotome development(GO:0061056)
0.1 0.8 GO:0072676 lymphocyte migration(GO:0072676)
0.1 0.9 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.5 GO:0090075 relaxation of muscle(GO:0090075)
0.1 0.6 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.1 0.8 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 1.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 1.2 GO:0001556 oocyte maturation(GO:0001556)
0.1 0.5 GO:0048730 epidermis morphogenesis(GO:0048730)
0.1 0.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.7 GO:0009648 photoperiodism(GO:0009648)
0.1 0.2 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.1 1.4 GO:0009408 response to heat(GO:0009408)
0.1 0.9 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.2 GO:0071867 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.1 0.7 GO:0050688 regulation of defense response to virus(GO:0050688)
0.1 1.0 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 1.2 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 1.0 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 1.3 GO:0051923 sulfation(GO:0051923)
0.0 0.4 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.5 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.2 GO:0007613 memory(GO:0007613)
0.0 0.2 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.4 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.0 0.9 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.4 GO:0050975 sensory perception of touch(GO:0050975)
0.0 1.2 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.7 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 2.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:1990697 protein depalmitoleylation(GO:1990697)
0.0 0.5 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.8 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.7 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.3 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.5 GO:0061647 histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.0 0.8 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 1.2 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.6 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.6 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.2 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.5 GO:1990090 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.0 3.6 GO:0048511 rhythmic process(GO:0048511)
0.0 0.6 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 0.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0016139 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0032728 interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648) positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.8 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 1.2 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 1.1 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.3 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.0 1.3 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.8 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.9 GO:0006334 nucleosome assembly(GO:0006334)
0.0 5.4 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 1.2 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 1.0 GO:0007416 synapse assembly(GO:0007416)
0.0 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0044854 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.5 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.3 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.5 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.5 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.0 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 4.1 GO:0034765 regulation of ion transmembrane transport(GO:0034765)
0.0 2.1 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.4 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.1 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 0.4 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.7 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.1 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.0 1.1 GO:0007605 sensory perception of sound(GO:0007605)
0.0 3.3 GO:0006869 lipid transport(GO:0006869)
0.0 0.6 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.3 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0 0.1 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 0.0 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.6 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:0007076 mitotic chromosome condensation(GO:0007076)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0031213 RSF complex(GO:0031213)
0.5 2.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.3 1.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.3 1.9 GO:0043194 axon initial segment(GO:0043194)
0.3 1.6 GO:0005845 mRNA cap binding complex(GO:0005845)
0.2 0.7 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.2 1.8 GO:0033010 paranodal junction(GO:0033010)
0.2 2.1 GO:0098982 GABA-ergic synapse(GO:0098982)
0.2 1.7 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 0.7 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.1 0.6 GO:1990909 Wnt signalosome(GO:1990909)
0.1 2.1 GO:0044545 NSL complex(GO:0044545)
0.1 1.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.6 GO:0005883 neurofilament(GO:0005883)
0.1 1.0 GO:0030428 cell septum(GO:0030428)
0.1 0.8 GO:0016586 RSC complex(GO:0016586)
0.1 1.8 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.4 GO:0030314 junctional membrane complex(GO:0030314)
0.1 1.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.4 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 1.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.6 GO:0070449 elongin complex(GO:0070449)
0.1 0.5 GO:0035060 brahma complex(GO:0035060)
0.1 1.7 GO:0005844 polysome(GO:0005844)
0.1 1.8 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 2.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.5 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.0 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.9 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.3 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 3.1 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0016234 inclusion body(GO:0016234)
0.0 2.4 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 1.0 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 2.6 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.9 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.5 GO:0005921 gap junction(GO:0005921)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 0.4 GO:0071004 U2-type prespliceosome(GO:0071004) prespliceosome(GO:0071010)
0.0 0.3 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 1.7 GO:0005884 actin filament(GO:0005884)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.0 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.5 GO:0030175 filopodium(GO:0030175)
0.0 0.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.9 GO:0030136 clathrin-coated vesicle(GO:0030136)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.5 1.9 GO:0097108 hedgehog family protein binding(GO:0097108)
0.4 1.6 GO:0070883 pre-miRNA binding(GO:0070883)
0.4 1.2 GO:0030882 lipid antigen binding(GO:0030882)
0.4 2.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.4 4.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.3 2.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.3 0.9 GO:1901612 cardiolipin binding(GO:1901612)
0.3 2.7 GO:0008420 CTD phosphatase activity(GO:0008420)
0.3 2.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.3 0.9 GO:0052834 inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.2 0.7 GO:0047690 aspartyltransferase activity(GO:0047690)
0.2 1.7 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 1.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 0.6 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.2 0.6 GO:0070097 delta-catenin binding(GO:0070097)
0.2 3.0 GO:0030552 cAMP binding(GO:0030552)
0.2 0.5 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087)
0.1 1.2 GO:0034452 dynactin binding(GO:0034452)
0.1 0.7 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 1.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 1.4 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.8 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 1.0 GO:0004100 chitin synthase activity(GO:0004100)
0.1 0.8 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.8 GO:0035173 histone kinase activity(GO:0035173)
0.1 2.1 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 0.6 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 1.0 GO:0016936 galactoside binding(GO:0016936)
0.1 0.4 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 1.3 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.4 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 1.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 1.3 GO:0033691 sialic acid binding(GO:0033691)
0.1 1.3 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.5 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.1 3.6 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 0.2 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)
0.1 0.9 GO:0042285 xylosyltransferase activity(GO:0042285)
0.1 0.6 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 3.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.8 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.5 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.8 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 1.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 1.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.2 GO:0004557 alpha-galactosidase activity(GO:0004557)
0.1 1.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 1.6 GO:0008483 transaminase activity(GO:0008483)
0.1 0.7 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 1.3 GO:0004707 MAP kinase activity(GO:0004707)
0.0 2.4 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.8 GO:0033549 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.0 1.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.1 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.2 GO:0005461 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 1.8 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 5.5 GO:0042393 histone binding(GO:0042393)
0.0 0.1 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.0 0.4 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.4 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.8 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.0 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 1.2 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.5 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.8 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 1.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 6.9 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.3 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 3.5 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.2 GO:0034595 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.0 0.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.7 GO:0005178 integrin binding(GO:0005178)
0.0 1.2 GO:0008201 heparin binding(GO:0008201)
0.0 1.2 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.5 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.3 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.2 GO:0004890 GABA-A receptor activity(GO:0004890)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 2.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 0.7 PID REELIN PATHWAY Reelin signaling pathway
0.1 0.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.3 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.9 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 2.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.9 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.6 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 3.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.2 1.7 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 1.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 2.7 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.1 1.4 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 0.5 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.1 1.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 2.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 2.9 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.1 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.7 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.1 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 0.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.6 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.1 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway