Project

PRJEB1986: zebrafish developmental stages transcriptome

Navigation
Downloads

Results for maza+mazb

Z-value: 4.71

Motif logo

Transcription factors associated with maza+mazb

Gene Symbol Gene ID Gene Info
ENSDARG00000063555 si_ch211-166g5.4
ENSDARG00000087330 MYC-associated zinc finger protein a (purine-binding transcription factor)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mazadr11_v1_chr3_-_21106093_21106093-0.436.7e-02Click!
si:ch211-166g5.4dr11_v1_chr12_-_3773869_3773869-0.331.7e-01Click!

Activity profile of maza+mazb motif

Sorted Z-values of maza+mazb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_6954984 23.23 ENSDART00000145610
si:ch211-255g12.6
chr3_-_30861177 19.24 ENSDART00000154811
SH3 and multiple ankyrin repeat domains 1
chr2_-_43168292 18.31 ENSDART00000132588
cAMP responsive element modulator a
chr18_-_16123222 17.87 ENSDART00000061189
sarcospan (Kras oncogene-associated gene)
chr19_-_5125663 17.63 ENSDART00000005547
ENSDART00000132642
guanine nucleotide binding protein (G protein), beta polypeptide 3b
chr11_+_36989696 17.43 ENSDART00000045888
transketolase a
chr14_-_30642819 16.50 ENSDART00000078154
neuronal PAS domain protein 4a
chr5_-_67878064 15.91 ENSDART00000111203
transgelin 3a
chr21_+_1143141 15.58 ENSDART00000178294

chr11_-_44030962 14.14 ENSDART00000171910

chr11_-_11518469 13.89 ENSDART00000104254
keratin 15
chr6_+_54888493 13.70 ENSDART00000113331
neuron navigator 1b
chr4_-_77557279 12.99 ENSDART00000180113

chr19_+_43123331 12.46 ENSDART00000187836

chr11_-_1291012 11.88 ENSDART00000158390
ATPase plasma membrane Ca2+ transporting 2
chr8_+_22931427 11.68 ENSDART00000063096
synaptophysin a
chr17_-_46457622 11.50 ENSDART00000130215
transmembrane protein 179
chr19_-_26863626 11.32 ENSDART00000145568
proline-rich transmembrane protein 1
chr24_+_37080771 11.18 ENSDART00000159942
potassium voltage-gated channel, Shaw-related subfamily, member 3b
chr10_-_44026369 10.91 ENSDART00000185456
crystallin, beta B1
chr11_-_32723851 10.81 ENSDART00000155592
protocadherin 17
chr16_-_17207754 10.21 ENSDART00000063804
wu:fj39g12
chr19_-_25301711 10.16 ENSDART00000175739
regulating synaptic membrane exocytosis 3
chr4_+_20255160 10.08 ENSDART00000188658
leucine-rich repeats and transmembrane domains 2a
chr3_+_37827373 10.00 ENSDART00000039517
acid-sensing (proton-gated) ion channel 2
chr18_-_51015718 9.94 ENSDART00000190698

chr5_+_9348284 9.72 ENSDART00000149417
T-cell acute lymphocytic leukemia 2
chr7_-_10606 9.70 ENSDART00000192650
ENSDART00000186761

chr3_-_30625219 9.50 ENSDART00000151698
synaptotagmin III
chr12_+_5530247 9.35 ENSDART00000114637
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr2_-_44183451 9.28 ENSDART00000111246
cell adhesion molecule 3
chr7_-_72208248 9.19 ENSDART00000108916
zmp:0000001168
chr5_-_37935607 9.09 ENSDART00000141233
ENSDART00000084868
ENSDART00000125857
sodium channel, voltage-gated, type IV, beta b
chr9_+_13714379 9.07 ENSDART00000017593
ENSDART00000145503
transmembrane protein 237a
chr21_+_5169154 9.01 ENSDART00000102559
zgc:122979
chr13_+_28701233 9.00 ENSDART00000135931
si:ch211-67n3.9
chr25_-_30047477 8.96 ENSDART00000164859

chr14_+_22172047 8.95 ENSDART00000114750
ENSDART00000148259
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr18_-_46763170 8.95 ENSDART00000171880
delta/notch-like EGF repeat containing
chr21_+_25660613 8.93 ENSDART00000134017
si:dkey-17e16.15
chr19_-_1961024 8.86 ENSDART00000108784
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr13_+_1100197 8.83 ENSDART00000139560
protein phosphatase 3, regulatory subunit B, alpha a
chr19_-_5254699 8.78 ENSDART00000081951
syntaxin 1B
chr23_-_35756115 8.68 ENSDART00000043429
junctophilin 2
chr25_+_37366698 8.67 ENSDART00000165400
ENSDART00000192589
solute carrier family 1 (glial high affinity glutamate transporter), member 2b
chr2_+_22694382 8.58 ENSDART00000139196
kinesin family member 1Ab
chr1_+_37391141 8.53 ENSDART00000083593
ENSDART00000168647
SPARC-like 1
chr4_-_17793152 8.53 ENSDART00000134080
myosin binding protein C, slow type
chr3_+_22327738 8.52 ENSDART00000055675
growth hormone 1
chr3_+_32425202 8.47 ENSDART00000156464
proline rich 12b
chr2_-_5014939 8.44 ENSDART00000164506
discs, large (Drosophila) homolog 1, like
chr3_+_54168007 8.33 ENSDART00000109894
olfactomedin 2a
chr3_-_28120092 8.31 ENSDART00000151143
RNA binding fox-1 homolog 1
chr4_+_5537101 8.30 ENSDART00000008692
si:dkey-14d8.7
chr4_-_6459863 8.24 ENSDART00000138367
forkhead box P2
chr6_+_38381957 8.22 ENSDART00000087300
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr4_+_2619132 8.14 ENSDART00000128807
G protein-coupled receptor 22a
chr24_-_38110779 8.07 ENSDART00000147783
c-reactive protein, pentraxin-related
chr20_-_25518488 8.01 ENSDART00000186993
cytochrome P450, family 2, subfamily N, polypeptide 13
chr7_-_58098814 7.97 ENSDART00000147287
ENSDART00000043984
ankyrin 2b, neuronal
chr13_+_27073901 7.94 ENSDART00000146227
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr21_-_37889727 7.90 ENSDART00000163612
ENSDART00000180958
gamma-aminobutyric acid (GABA) A receptor, beta 4
chr6_+_54358529 7.89 ENSDART00000153704
ankyrin repeat and sterile alpha motif domain containing 1Ab
chr2_-_44183613 7.89 ENSDART00000079596
cell adhesion molecule 3
chr22_-_21845685 7.81 ENSDART00000105564
amino-terminal enhancer of split
chr1_-_31505144 7.81 ENSDART00000087115
regulating synaptic membrane exocytosis 1b
chr24_+_36452927 7.65 ENSDART00000168181
zgc:114120
chr22_+_32120156 7.64 ENSDART00000149666
dedicator of cytokinesis 3
chr10_+_22724059 7.63 ENSDART00000136123
lysine (K)-specific demethylase 6B, b
chr12_-_22039350 7.58 ENSDART00000153187
thyroid hormone receptor alpha b
chr10_-_37337579 7.52 ENSDART00000147705
oligodendrocyte myelin glycoprotein a
chr1_+_12009673 7.48 ENSDART00000080100
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr3_-_36115339 7.45 ENSDART00000187406
ENSDART00000123505
ENSDART00000151775
RAB11 family interacting protein 4 (class II) a
chr11_-_44543082 7.45 ENSDART00000099568
G protein-coupled receptor 137Bb
chr12_-_45349849 7.38 ENSDART00000183036
Danio rerio uncharacterized LOC100332446 (LOC100332446), mRNA.
chr4_+_55758103 7.34 ENSDART00000185964

chr9_-_49531762 7.33 ENSDART00000121875
xin actin binding repeat containing 2b
chr7_+_427503 7.27 ENSDART00000185942
neurexin 2
chr22_+_38159823 7.21 ENSDART00000104527
transmembrane 4 L six family member 18
chr13_-_21739142 7.19 ENSDART00000078460
si:dkey-191g9.5
chr14_-_7207961 7.18 ENSDART00000167994
ENSDART00000166532
storkhead box 2b
chr20_+_15982482 7.16 ENSDART00000020999
angiopoietin-like 1a
chr23_+_14217508 7.13 ENSDART00000143618
baculoviral IAP repeat containing 7
chr10_-_35542071 7.10 ENSDART00000162139
si:ch211-244c8.4
chr7_+_528593 7.08 ENSDART00000091955
neurexin 2b
chr15_-_12500938 7.04 ENSDART00000159627
sodium channel, voltage-gated, type IV, beta a
chr24_-_1985007 7.02 ENSDART00000189870
par-3 family cell polarity regulator
chr2_-_9646857 7.01 ENSDART00000056901
zgc:153615
chr3_-_3209432 6.97 ENSDART00000140635
si:ch211-229i14.2
chr14_-_2369849 6.90 ENSDART00000180422
ENSDART00000189731
ENSDART00000111748
protocadherin b
chr15_-_12113045 6.85 ENSDART00000159879
Down syndrome cell adhesion molecule like 1
chr8_+_46418996 6.81 ENSDART00000144285
si:ch211-196g2.4
chr8_-_14052349 6.80 ENSDART00000135811
ATPase plasma membrane Ca2+ transporting 3a
chr8_-_22660678 6.75 ENSDART00000181258
IQ motif and Sec7 domain 2a
chr1_-_22370660 6.74 ENSDART00000127506
si:ch73-380n15.2
chr18_+_21122818 6.72 ENSDART00000060015
ENSDART00000060184
choline kinase alpha
chr19_-_6193448 6.70 ENSDART00000151405
Ets2 repressor factor
chr25_-_12788370 6.70 ENSDART00000158551
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr3_-_52614747 6.65 ENSDART00000154365
tripartite motif containing 35-13
chr20_+_13969414 6.63 ENSDART00000049864
retinal degeneration 3
chr25_+_19954576 6.61 ENSDART00000149335
potassium voltage-gated channel, shaker-related subfamily, member 1a
chr18_+_12058403 6.60 ENSDART00000140854
ENSDART00000193632
ENSDART00000190519
ENSDART00000190685
ENSDART00000112671
bicaudal D homolog 1a
chr13_-_349952 6.56 ENSDART00000133731
ENSDART00000140326
ENSDART00000189389
ENSDART00000185865
ENSDART00000109634
ENSDART00000147058
ENSDART00000142695
si:ch1073-291c23.2
chr7_-_71837213 6.50 ENSDART00000168645
ENSDART00000160512
calcium channel, voltage-dependent, beta 2a
chr16_-_36798783 6.47 ENSDART00000145697
calbindin 1
chr23_+_6232895 6.46 ENSDART00000139795
synaptotagmin IIa
chr19_-_9760994 6.37 ENSDART00000139727
si:dkey-14o18.2
chr3_+_37824268 6.32 ENSDART00000137038
acid-sensing (proton-gated) ion channel 2
chr2_+_55199721 6.29 ENSDART00000016143
zmp:0000000521
chr1_-_45647846 6.29 ENSDART00000186881

chr1_+_44491077 6.24 ENSDART00000073736
reticulon 4 receptor-like 2 a
chr7_-_6604623 6.24 ENSDART00000172874
potassium inwardly-rectifying channel, subfamily J, member 10a
chr19_-_32804535 6.21 ENSDART00000175613
ENSDART00000052098
5'-nucleotidase, cytosolic IAa
chr4_+_1146346 6.14 ENSDART00000166467
cholinergic receptor, muscarinic 2a
chr14_-_1535430 6.11 ENSDART00000179228

chr20_-_14665002 6.07 ENSDART00000152816
secernin 2
chr15_-_2188332 6.00 ENSDART00000138941
ENSDART00000009564
short stature homeobox 2
chr6_+_22597362 5.94 ENSDART00000131242
cytoglobin 2
chr11_+_39969048 5.94 ENSDART00000193693
period circadian clock 3
chr12_+_48744016 5.86 ENSDART00000175518

chr25_-_19395476 5.80 ENSDART00000182622
microtubule-associated protein 1Ab
chr12_+_32729470 5.76 ENSDART00000175712
RNA binding fox-1 homolog 3a
chr21_-_21373242 5.72 ENSDART00000079629
protein phosphatase, Mg2+/Mn2+ dependent, 1Nb (putative)
chr11_-_97817 5.71 ENSDART00000092903
engulfment and cell motility 2
chr6_+_59029485 5.68 ENSDART00000050140

chr13_+_38430466 5.65 ENSDART00000132691
adhesion G protein-coupled receptor B3
chr4_-_1360495 5.65 ENSDART00000164623
pleiotrophin
chr24_-_38579066 5.64 ENSDART00000099869
solute carrier family 17 (vesicular glutamate transporter), member 7b
chr16_-_22683038 5.62 ENSDART00000138130
S100 calcium binding protein T
chr20_+_50115335 5.57 ENSDART00000031139
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4b
chr7_+_27977065 5.50 ENSDART00000089574
tubby bipartite transcription factor
chr8_-_51293265 5.46 ENSDART00000127875
ENSDART00000181145
bone morphogenetic protein 1a
chr19_+_9032073 5.43 ENSDART00000127755
ash1 (absent, small, or homeotic)-like (Drosophila)
chr16_-_12914288 5.41 ENSDART00000184221
calcium channel, voltage-dependent, gamma subunit 8b
chr4_+_20263097 5.38 ENSDART00000138820
leucine-rich repeats and transmembrane domains 2a
chr25_+_35706493 5.32 ENSDART00000176741
kinesin family member 21A
chr8_-_20230559 5.31 ENSDART00000193677
MLLT1, super elongation complex subunit a
chr3_-_10634438 5.27 ENSDART00000093037
ENSDART00000130761
ENSDART00000156617
mitogen-activated protein kinase kinase 4a
chr15_+_47903864 5.16 ENSDART00000063835
orthodenticle homolog 5
chr24_-_31942656 5.15 ENSDART00000180308
ENSDART00000016879
complement component 1, q subcomponent-like 3a
chr24_-_6501211 5.14 ENSDART00000186241
ENSDART00000109040
ENSDART00000136154
G protein-coupled receptor 158a
chr8_+_13849999 5.11 ENSDART00000143784
double C2-like domains, delta
chr16_-_27640995 5.10 ENSDART00000019658
NAC alpha domain containing
chr5_+_5689476 5.08 ENSDART00000022729
un-named sa808
chr7_-_32598383 5.03 ENSDART00000111055
potassium voltage-gated channel, shaker-related subfamily, member 4
chr20_+_50184934 5.02 ENSDART00000158388
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4b
chr8_-_5847533 5.00 ENSDART00000192489

chr12_-_13886952 5.00 ENSDART00000110503
ADAM metallopeptidase domain 11
chr21_+_11244068 4.98 ENSDART00000163432
AT-rich interaction domain 6
chr15_-_28618502 4.96 ENSDART00000086902
solute carrier family 6 (neurotransmitter transporter), member 4a
chr15_-_5467477 4.94 ENSDART00000123839
arrestin, beta 1
chr6_+_58492201 4.93 ENSDART00000156375
potassium voltage-gated channel, KQT-like subfamily, member 2b
chr19_+_9533008 4.93 ENSDART00000104607
family with sequence similarity 131, member Ba
chr20_-_51727860 4.86 ENSDART00000147044
BRO1 domain and CAAX motif containing
chr3_-_28075756 4.79 ENSDART00000122037
RNA binding fox-1 homolog 1
chr1_-_29045426 4.79 ENSDART00000019770
glycoprotein M6Ba
chr7_+_36539124 4.78 ENSDART00000173653
chromodomain helicase DNA binding protein 9
chr15_-_33925851 4.75 ENSDART00000187807
ENSDART00000187780
myelin associated glycoprotein
chr1_+_45351890 4.75 ENSDART00000145486
si:ch211-243a20.3
chr2_-_50372467 4.73 ENSDART00000108900
contactin associated protein like 2b
chr1_+_6307305 4.71 ENSDART00000183870

chr21_+_26697536 4.70 ENSDART00000004109
guanine nucleotide binding protein (G protein), gamma 3
chr18_-_41219790 4.70 ENSDART00000162387
ENSDART00000193753
zinc finger and BTB domain containing 38
chr2_+_48073972 4.68 ENSDART00000186442
Kruppel-like factor 6b
chr21_+_41649336 4.67 ENSDART00000164694
ENSDART00000181539
protein phosphatase 2, regulatory subunit B, beta b
chr25_+_336503 4.66 ENSDART00000160395

chr15_-_37543591 4.65 ENSDART00000180400
lysine (K)-specific methyltransferase 2Bb
chr5_-_68022631 4.63 ENSDART00000143199
WAS protein family, member 3a
chr10_-_9115383 4.62 ENSDART00000139324
si:dkeyp-41f9.3
chr20_-_34754617 4.62 ENSDART00000148066
zinc finger protein 395b
chr1_+_44127292 4.62 ENSDART00000160542
calcium binding protein 2a
chr8_+_14855471 4.58 ENSDART00000134775
si:dkey-21p1.3
chr2_-_4787566 4.57 ENSDART00000160663
ENSDART00000157808
tyrosine kinase, non-receptor, 2b
chr11_-_21304452 4.53 ENSDART00000163008
si:dkey-85p17.3
chr23_-_31693309 4.47 ENSDART00000146327
serum/glucocorticoid regulated kinase 1
chr22_+_883678 4.47 ENSDART00000140588
serine/threonine kinase 38b
chr10_-_7974155 4.47 ENSDART00000147368
ENSDART00000075524
oxysterol binding protein 2
chr2_-_5776030 4.46 ENSDART00000133851
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2b
chr20_+_33532296 4.46 ENSDART00000153153
potassium voltage-gated channel, subfamily F, member 1a
chr13_-_638485 4.41 ENSDART00000066080
ENSDART00000128969
slit homolog 1a (Drosophila)
chr19_-_41213718 4.39 ENSDART00000077121
pyruvate dehydrogenase kinase, isozyme 4
chr18_-_46464501 4.38 ENSDART00000040669
SPHK1 interactor, AKAP domain containing
chr16_+_24842662 4.36 ENSDART00000157333
si:dkey-79d12.6
chr9_-_704667 4.34 ENSDART00000147092
CASP8 and FADD-like apoptosis regulator b
chr14_+_40685469 4.34 ENSDART00000172839
tenomodulin
chr8_+_3496204 4.32 ENSDART00000085993
paxillin b
chr21_+_45841731 4.30 ENSDART00000038657
fatty acid hydroxylase domain containing 2
chr8_+_48603398 4.30 ENSDART00000074900
zgc:195023
chr5_-_5831037 4.30 ENSDART00000112856
zmp:0000000846
chr5_+_43427841 4.30 ENSDART00000177895
Rho-related BTB domain containing 2a
chr6_-_4228640 4.28 ENSDART00000162497
ENSDART00000179923
trafficking protein, kinesin binding 2
chr2_-_38125657 4.27 ENSDART00000143433
cerebellin 12
chr8_+_16990120 4.24 ENSDART00000018934
phosphodiesterase 4D, cAMP-specific
chr12_+_32388860 4.23 ENSDART00000075568
noggin 3
chr2_+_7192966 4.20 ENSDART00000142735
si:ch211-13f8.1
chr14_+_29550323 4.20 ENSDART00000157943
si:dkey-34l15.2
chr2_+_33052360 4.17 ENSDART00000134651
ring finger protein 220a
chr24_-_29729799 4.17 ENSDART00000181250
si:ch73-383g2.1
chr5_-_24642026 4.17 ENSDART00000139522
si:ch211-106a19.1
chr9_-_3834686 4.15 ENSDART00000141492
myosin IIIB

Network of associatons between targets according to the STRING database.

First level regulatory network of maza+mazb

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 17.4 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
3.3 16.5 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
3.2 13.0 GO:0006837 serotonin transport(GO:0006837) serotonin uptake(GO:0051610)
3.0 8.9 GO:0014014 negative regulation of gliogenesis(GO:0014014)
2.5 10.1 GO:0003161 cardiac conduction system development(GO:0003161)
2.5 7.5 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
2.5 7.5 GO:0060292 long term synaptic depression(GO:0060292)
2.5 7.4 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
1.8 8.9 GO:0030219 megakaryocyte differentiation(GO:0030219)
1.8 8.8 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
1.7 8.5 GO:0050996 positive regulation of lipid catabolic process(GO:0050996)
1.6 6.5 GO:1900271 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
1.6 8.0 GO:0036371 protein localization to T-tubule(GO:0036371)
1.6 34.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
1.3 3.8 GO:0042368 calcitriol biosynthetic process from calciol(GO:0036378) vitamin D biosynthetic process(GO:0042368) cellular alcohol metabolic process(GO:0044107) cellular alcohol biosynthetic process(GO:0044108)
1.2 4.9 GO:0060300 microglial cell activation(GO:0001774) regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
1.1 5.7 GO:0016322 neuron remodeling(GO:0016322)
1.1 6.6 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260)
1.0 4.1 GO:0010226 response to lithium ion(GO:0010226)
1.0 4.0 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.9 4.7 GO:0099612 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.9 5.5 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.9 5.5 GO:0032964 collagen biosynthetic process(GO:0032964)
0.9 6.2 GO:0036268 swimming(GO:0036268)
0.9 3.5 GO:0060074 synapse maturation(GO:0060074)
0.9 4.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.9 2.6 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.8 7.6 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.8 7.6 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.8 3.8 GO:0043029 T cell homeostasis(GO:0043029)
0.7 3.7 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.7 4.4 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
0.7 3.6 GO:0060251 regulation of glial cell proliferation(GO:0060251)
0.7 4.3 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.7 6.4 GO:0016121 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.7 5.6 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.6 6.4 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.6 2.5 GO:0090244 endodermal digestive tract morphogenesis(GO:0061031) Wnt signaling pathway involved in somitogenesis(GO:0090244) negative regulation of canonical Wnt signaling pathway involved in heart development(GO:1905067)
0.6 1.9 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.6 3.6 GO:0015846 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.6 1.8 GO:0001783 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) negative regulation of B cell proliferation(GO:0030889) negative regulation of B cell activation(GO:0050869) lymphocyte apoptotic process(GO:0070227) regulation of lymphocyte apoptotic process(GO:0070228)
0.6 1.8 GO:0035992 tendon formation(GO:0035992)
0.6 3.5 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.6 3.4 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.6 4.0 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.6 2.8 GO:0048025 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.5 5.5 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.5 3.2 GO:0006013 mannose metabolic process(GO:0006013)
0.5 8.2 GO:0045471 response to ethanol(GO:0045471)
0.5 16.8 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.5 2.5 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.5 5.3 GO:0060079 excitatory postsynaptic potential(GO:0060079) chemical synaptic transmission, postsynaptic(GO:0099565)
0.5 6.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.5 13.8 GO:0099633 protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645)
0.5 4.7 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.4 1.8 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.4 4.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.4 10.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.4 3.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.4 9.6 GO:0030537 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.4 7.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.4 2.8 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.4 1.2 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.4 5.0 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.4 4.2 GO:0035844 cloaca development(GO:0035844)
0.4 3.1 GO:0051013 microtubule severing(GO:0051013)
0.4 6.2 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.4 10.5 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.4 7.9 GO:0009649 entrainment of circadian clock(GO:0009649)
0.4 16.2 GO:0021854 hypothalamus development(GO:0021854)
0.3 5.8 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.3 3.4 GO:0006108 malate metabolic process(GO:0006108)
0.3 8.4 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.3 6.7 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.3 3.7 GO:0000710 meiotic mismatch repair(GO:0000710)
0.3 2.9 GO:1904861 excitatory synapse assembly(GO:1904861)
0.3 9.1 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.3 1.6 GO:0031650 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.3 8.7 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.3 4.4 GO:0045773 positive regulation of axon extension(GO:0045773)
0.3 10.8 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.3 9.7 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.3 5.9 GO:0015671 oxygen transport(GO:0015671)
0.3 2.8 GO:0099639 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.3 3.3 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.3 2.8 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.3 1.9 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.3 2.6 GO:0000305 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.3 5.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.3 3.9 GO:0031060 regulation of histone methylation(GO:0031060)
0.3 9.5 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.3 6.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.2 15.5 GO:0050919 negative chemotaxis(GO:0050919)
0.2 30.6 GO:0051260 protein homooligomerization(GO:0051260)
0.2 10.3 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 13.9 GO:0001764 neuron migration(GO:0001764)
0.2 5.1 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.2 4.8 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.2 2.6 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.2 4.4 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.2 0.2 GO:0002931 response to ischemia(GO:0002931)
0.2 3.4 GO:0042407 cristae formation(GO:0042407)
0.2 0.9 GO:0090579 establishment of mitotic sister chromatid cohesion(GO:0034087) establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169) transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.2 4.7 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.2 3.3 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2 3.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2 9.3 GO:0061512 protein localization to cilium(GO:0061512)
0.2 2.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 7.1 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.2 15.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.2 4.0 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.2 16.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.2 0.6 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.2 0.4 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.2 35.8 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.2 0.8 GO:0042481 regulation of odontogenesis(GO:0042481)
0.2 3.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 1.7 GO:0072576 liver morphogenesis(GO:0072576)
0.2 1.5 GO:0070293 renal absorption(GO:0070293)
0.2 1.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 5.2 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.2 8.2 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.2 2.0 GO:0030534 adult behavior(GO:0030534)
0.2 0.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 7.4 GO:0032465 regulation of cytokinesis(GO:0032465)
0.1 5.7 GO:0051781 positive regulation of cell division(GO:0051781)
0.1 4.5 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 3.1 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 15.3 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.1 3.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 3.4 GO:0051014 actin filament severing(GO:0051014)
0.1 3.6 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.1 4.3 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.1 1.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 0.8 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 2.4 GO:0010507 negative regulation of autophagy(GO:0010507)
0.1 1.5 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 0.9 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 8.5 GO:0048741 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.1 2.4 GO:0032526 response to retinoic acid(GO:0032526)
0.1 1.8 GO:0050796 regulation of insulin secretion(GO:0050796)
0.1 0.7 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.1 4.4 GO:0010675 regulation of cellular carbohydrate metabolic process(GO:0010675) regulation of glucose metabolic process(GO:0010906)
0.1 1.2 GO:0071384 response to corticosteroid(GO:0031960) response to glucocorticoid(GO:0051384) cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.1 12.4 GO:0034765 regulation of ion transmembrane transport(GO:0034765)
0.1 4.8 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 0.9 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 5.7 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 1.5 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 4.3 GO:0016126 sterol biosynthetic process(GO:0016126)
0.1 5.1 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 4.0 GO:0046058 cAMP metabolic process(GO:0046058)
0.1 7.0 GO:0051017 actin filament bundle assembly(GO:0051017)
0.1 1.6 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 1.5 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.1 4.8 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.1 4.5 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.1 3.2 GO:0007254 JNK cascade(GO:0007254)
0.1 1.8 GO:0071456 cellular response to hypoxia(GO:0071456)
0.1 15.0 GO:0007601 visual perception(GO:0007601)
0.1 1.4 GO:0030199 collagen fibril organization(GO:0030199)
0.1 2.4 GO:0045332 phospholipid translocation(GO:0045332)
0.1 0.7 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 1.7 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.1 3.1 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.1 10.4 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.1 2.5 GO:0001935 endothelial cell proliferation(GO:0001935)
0.1 1.2 GO:0070167 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.1 0.7 GO:1902807 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.1 0.8 GO:0051452 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.1 3.2 GO:0008016 regulation of heart contraction(GO:0008016)
0.1 1.8 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.1 3.5 GO:0006909 phagocytosis(GO:0006909)
0.0 3.8 GO:0017157 regulation of exocytosis(GO:0017157)
0.0 1.5 GO:0031102 neuron projection regeneration(GO:0031102)
0.0 2.2 GO:0007605 sensory perception of sound(GO:0007605)
0.0 3.5 GO:0007626 locomotory behavior(GO:0007626)
0.0 2.1 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 1.8 GO:0001706 endoderm formation(GO:0001706)
0.0 8.7 GO:0006869 lipid transport(GO:0006869)
0.0 0.5 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 3.3 GO:0021782 glial cell development(GO:0021782)
0.0 0.2 GO:0007183 SMAD protein complex assembly(GO:0007183) regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 1.9 GO:0006813 potassium ion transport(GO:0006813)
0.0 3.4 GO:0014032 neural crest cell development(GO:0014032)
0.0 5.0 GO:0051321 meiotic cell cycle(GO:0051321)
0.0 6.8 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 1.1 GO:0048268 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919) clathrin coat assembly(GO:0048268)
0.0 1.0 GO:0016358 dendrite development(GO:0016358)
0.0 0.7 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.2 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.5 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 4.4 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.5 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 1.4 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.2 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.8 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.3 GO:0019229 regulation of vasoconstriction(GO:0019229)
0.0 0.1 GO:0010002 cardioblast differentiation(GO:0010002) negative regulation of muscle organ development(GO:0048635)
0.0 2.9 GO:0045087 innate immune response(GO:0045087)
0.0 1.5 GO:0007018 microtubule-based movement(GO:0007018)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 18.6 GO:0043194 axon initial segment(GO:0043194)
1.7 8.7 GO:0030314 junctional membrane complex(GO:0030314)
1.3 6.5 GO:0042584 chromaffin granule membrane(GO:0042584)
1.0 4.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
1.0 28.0 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.9 5.7 GO:0043083 synaptic cleft(GO:0043083)
0.8 5.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.8 17.9 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.7 5.4 GO:0016586 RSC complex(GO:0016586)
0.7 6.6 GO:0033270 paranode region of axon(GO:0033270)
0.6 11.2 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.6 32.9 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.6 4.7 GO:0033010 paranodal junction(GO:0033010)
0.6 8.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.6 6.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.6 18.9 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.5 7.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.5 8.0 GO:0030315 T-tubule(GO:0030315)
0.4 3.5 GO:0032019 mitochondrial cloud(GO:0032019)
0.4 6.9 GO:0043195 terminal bouton(GO:0043195)
0.4 7.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.4 5.6 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.4 2.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.4 20.5 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.3 19.2 GO:0048786 presynaptic active zone(GO:0048786)
0.3 21.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.3 3.4 GO:0061617 MICOS complex(GO:0061617)
0.3 4.6 GO:0031209 SCAR complex(GO:0031209)
0.3 1.1 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.3 3.5 GO:0030056 hemidesmosome(GO:0030056)
0.3 9.1 GO:0035869 ciliary transition zone(GO:0035869)
0.2 3.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 2.8 GO:0016580 Sin3 complex(GO:0016580)
0.2 3.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 2.8 GO:0005922 connexon complex(GO:0005922)
0.2 4.5 GO:0009925 basal plasma membrane(GO:0009925)
0.2 2.6 GO:0044295 axonal growth cone(GO:0044295)
0.2 4.0 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.2 7.4 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2 16.1 GO:0005882 intermediate filament(GO:0005882)
0.2 10.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 1.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 5.6 GO:0030426 growth cone(GO:0030426)
0.2 5.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 2.8 GO:0030427 site of polarized growth(GO:0030427)
0.2 15.1 GO:0043025 neuronal cell body(GO:0043025)
0.1 3.7 GO:0000795 synaptonemal complex(GO:0000795)
0.1 4.8 GO:0030175 filopodium(GO:0030175)
0.1 12.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 4.3 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 3.1 GO:0030496 midbody(GO:0030496)
0.1 1.9 GO:0030057 desmosome(GO:0030057)
0.1 7.7 GO:0014069 postsynaptic density(GO:0014069)
0.1 1.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.8 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 6.5 GO:0005871 kinesin complex(GO:0005871)
0.1 3.7 GO:0031941 filamentous actin(GO:0031941)
0.1 4.7 GO:0035097 histone methyltransferase complex(GO:0035097)
0.1 4.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 2.7 GO:0005902 microvillus(GO:0005902)
0.1 9.4 GO:0070382 exocytic vesicle(GO:0070382)
0.0 2.8 GO:0031201 SNARE complex(GO:0031201)
0.0 2.8 GO:0000139 Golgi membrane(GO:0000139)
0.0 4.2 GO:0016459 myosin complex(GO:0016459)
0.0 0.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 3.0 GO:0005814 centriole(GO:0005814)
0.0 4.5 GO:0043235 receptor complex(GO:0043235)
0.0 2.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 4.3 GO:0045202 synapse(GO:0045202)
0.0 1.0 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 9.8 GO:0005929 cilium(GO:0005929)
0.0 1.5 GO:0008305 integrin complex(GO:0008305)
0.0 3.4 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 14.1 GO:0031410 cytoplasmic vesicle(GO:0031410)
0.0 40.0 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 3.9 GO:0005938 cell cortex(GO:0005938)
0.0 17.0 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 4.3 GO:0005874 microtubule(GO:0005874)
0.0 0.7 GO:0005811 lipid particle(GO:0005811)
0.0 88.6 GO:0016021 integral component of membrane(GO:0016021)
0.0 20.3 GO:0005829 cytosol(GO:0005829)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 17.4 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
2.9 26.0 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
2.8 8.5 GO:0070186 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
2.2 6.7 GO:0042166 neurotransmitter binding(GO:0042165) acetylcholine binding(GO:0042166)
2.2 6.5 GO:0005499 vitamin D binding(GO:0005499)
1.9 7.5 GO:0071253 connexin binding(GO:0071253)
1.7 5.0 GO:0005335 serotonin:sodium symporter activity(GO:0005335) serotonin transmembrane transporter activity(GO:0015222)
1.4 16.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
1.3 3.8 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) cholesterol 26-hydroxylase activity(GO:0031073)
1.2 19.9 GO:0048495 Roundabout binding(GO:0048495)
1.2 6.1 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
1.2 5.9 GO:0055077 gap junction hemi-channel activity(GO:0055077)
1.1 5.3 GO:0008545 JUN kinase kinase activity(GO:0008545)
1.0 15.1 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.9 6.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.8 5.9 GO:0098809 nitrite reductase activity(GO:0098809)
0.8 6.6 GO:0034452 dynactin binding(GO:0034452)
0.8 7.6 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.8 35.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.7 5.9 GO:0001222 transcription corepressor binding(GO:0001222)
0.7 6.4 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.7 20.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.7 3.4 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.6 4.3 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.6 2.4 GO:0070513 death domain binding(GO:0070513)
0.6 3.6 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.6 5.6 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.6 31.0 GO:0044325 ion channel binding(GO:0044325)
0.6 6.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.6 18.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.5 4.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.5 7.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.5 2.6 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.5 4.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.5 8.8 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.4 8.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.4 8.0 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.4 5.0 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.4 2.6 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.4 16.8 GO:0008013 beta-catenin binding(GO:0008013)
0.3 10.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.3 16.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.3 7.4 GO:0031267 small GTPase binding(GO:0031267)
0.3 13.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 16.7 GO:0015485 cholesterol binding(GO:0015485)
0.3 3.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.3 2.9 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.3 7.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.3 6.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.3 1.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.3 3.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.3 1.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.3 10.0 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.3 5.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.3 10.5 GO:0051087 chaperone binding(GO:0051087)
0.3 2.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.3 1.0 GO:0015105 arsenite transmembrane transporter activity(GO:0015105)
0.3 2.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.3 2.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.3 3.5 GO:0030506 ankyrin binding(GO:0030506)
0.2 7.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.2 0.7 GO:0019777 Atg12 transferase activity(GO:0019777)
0.2 9.4 GO:0004180 carboxypeptidase activity(GO:0004180)
0.2 4.2 GO:0005080 protein kinase C binding(GO:0005080)
0.2 1.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 4.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 8.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 2.8 GO:0045159 myosin II binding(GO:0045159)
0.2 11.8 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.2 4.1 GO:0003785 actin monomer binding(GO:0003785)
0.2 5.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 3.7 GO:0030983 mismatched DNA binding(GO:0030983)
0.2 4.3 GO:0050811 GABA receptor binding(GO:0050811)
0.2 5.5 GO:0004016 adenylate cyclase activity(GO:0004016)
0.2 4.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 3.2 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.2 3.7 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.2 3.5 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.2 1.5 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.2 17.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.2 8.8 GO:0017124 SH3 domain binding(GO:0017124)
0.2 5.1 GO:0015459 potassium channel regulator activity(GO:0015459)
0.2 10.2 GO:0051427 hormone receptor binding(GO:0051427)
0.2 1.8 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 0.9 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 1.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 5.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 2.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 1.5 GO:0042562 hormone binding(GO:0042562)
0.1 1.7 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 10.3 GO:0019902 phosphatase binding(GO:0019902)
0.1 1.6 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 3.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 10.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 7.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 15.0 GO:0003777 microtubule motor activity(GO:0003777)
0.1 4.8 GO:0030145 manganese ion binding(GO:0030145)
0.1 1.1 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 3.1 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 3.4 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 7.7 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 3.9 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.8 GO:0030274 LIM domain binding(GO:0030274)
0.1 5.4 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.1 1.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 15.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.5 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 5.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 3.1 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 1.9 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 1.6 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.3 GO:0004945 angiotensin type I receptor activity(GO:0001596) angiotensin type II receptor activity(GO:0004945)
0.1 3.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 1.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.7 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 2.3 GO:0008198 ferrous iron binding(GO:0008198)
0.1 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 2.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 5.6 GO:0008201 heparin binding(GO:0008201)
0.1 4.5 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.1 5.1 GO:0051082 unfolded protein binding(GO:0051082)
0.1 10.5 GO:0015293 symporter activity(GO:0015293)
0.1 0.9 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1 4.4 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.1 4.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.8 GO:0051117 ATPase binding(GO:0051117)
0.1 15.0 GO:0008017 microtubule binding(GO:0008017)
0.1 19.3 GO:0005096 GTPase activator activity(GO:0005096)
0.0 9.3 GO:0042277 peptide binding(GO:0042277)
0.0 0.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 5.9 GO:0003774 motor activity(GO:0003774)
0.0 14.2 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.2 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.5 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.5 GO:0005178 integrin binding(GO:0005178)
0.0 1.4 GO:0015631 tubulin binding(GO:0015631)
0.0 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0042285 xylosyltransferase activity(GO:0042285)
0.0 2.4 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.2 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.8 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 12.2 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.2 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.3 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 4.3 GO:0061630 ubiquitin protein ligase activity(GO:0061630)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 9.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.5 7.5 PID CONE PATHWAY Visual signal transduction: Cones
0.5 8.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.3 5.7 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.2 3.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 8.4 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.2 6.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.2 6.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.2 2.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 5.9 PID NOTCH PATHWAY Notch signaling pathway
0.1 1.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 4.7 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 1.6 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 9.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 0.7 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 2.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 3.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 3.9 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 1.5 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 3.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 2.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 1.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 0.9 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 3.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 17.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.9 6.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.7 8.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.7 13.8 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.7 8.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.6 8.8 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.6 13.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.6 13.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.5 3.8 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.5 6.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.5 4.0 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.5 7.9 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.4 4.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.4 12.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.4 3.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.3 4.9 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.3 8.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.3 3.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 15.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 2.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 3.4 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.2 2.7 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2 3.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.2 2.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.2 1.7 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.2 7.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 3.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.6 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.1 1.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 5.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 0.9 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 3.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 3.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 3.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 1.0 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 2.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 0.9 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.7 REACTOME G1 PHASE Genes involved in G1 Phase