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PRJEB1986: zebrafish developmental stages transcriptome

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Results for maff+mafga+mafgb

Z-value: 1.36

Motif logo

Transcription factors associated with maff+mafga+mafgb

Gene Symbol Gene ID Gene Info
ENSDARG00000018109 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ga
ENSDARG00000028957 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
ENSDARG00000100097 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Gb
ENSDARG00000111050 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mafgadr11_v1_chr3_-_55404985_554049850.922.2e-08Click!
mafgbdr11_v1_chr11_+_45323455_453234550.918.9e-08Click!
maffdr11_v1_chr12_-_19346678_193466780.561.3e-02Click!

Activity profile of maff+mafga+mafgb motif

Sorted Z-values of maff+mafga+mafgb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_32526799 14.46 ENSDART00000185755
si:ch73-367p23.2
chr15_-_34418525 5.84 ENSDART00000147582
alkylglycerol monooxygenase
chr22_+_19289970 4.84 ENSDART00000137976
ENSDART00000132386
si:dkey-21e2.15
chr6_-_35446110 4.52 ENSDART00000058773
regulator of G protein signaling 16
chr20_+_35473288 3.87 ENSDART00000047195
meprin A, alpha (PABA peptide hydrolase), tandem duplicate 1
chr8_+_554531 3.84 ENSDART00000193623

chr19_-_703898 3.73 ENSDART00000181096
ENSDART00000121462
solute carrier family 6 (neutral amino acid transporter), member 19a, tandem duplicate 2
chr12_-_32421046 3.70 ENSDART00000075567
ectonucleotide pyrophosphatase/phosphodiesterase 7, tandem duplicate 1
chr15_-_44512461 3.19 ENSDART00000155456
glutamate receptor, ionotropic, AMPA 4a
chr3_-_39171968 3.16 ENSDART00000154494
si:dkeyp-57f11.2
chr21_-_45613564 3.10 ENSDART00000160324

chr21_-_43606502 3.09 ENSDART00000151030
si:ch73-362m14.4
chr9_+_1162216 3.08 ENSDART00000165295
serine/threonine kinase 24a (STE20 homolog, yeast)
chr8_+_53452681 3.04 ENSDART00000166705
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr22_+_19290199 3.00 ENSDART00000148173
si:dkey-21e2.15
chr15_-_34408777 2.85 ENSDART00000139934
alkylglycerol monooxygenase
chr10_+_29698467 2.81 ENSDART00000163402
discs, large homolog 2 (Drosophila)
chr10_-_25699454 2.73 ENSDART00000064376
superoxide dismutase 1, soluble
chr2_-_32505091 2.71 ENSDART00000141884
ENSDART00000056639
Fas apoptotic inhibitory molecule 2a
chr9_-_43071519 2.68 ENSDART00000109099
titin, tandem duplicate 2
chr12_-_31422433 2.66 ENSDART00000186075
ENSDART00000153172
ENSDART00000066256
vesicle transport through interaction with t-SNAREs 1A
chr5_-_7897316 2.65 ENSDART00000160743
ENSDART00000160912
opsin 4xb
chr16_-_12173554 2.64 ENSDART00000110567
ENSDART00000155935
calsyntenin 3
chr3_-_32169754 2.63 ENSDART00000179010
troponin T type 1 (skeletal, slow)
chr11_-_11458208 2.62 ENSDART00000005485
keratin 93
chr14_+_31721171 2.59 ENSDART00000173034
adhesion G protein-coupled receptor G4a
chr16_+_10777116 2.53 ENSDART00000190902
ATPase Na+/K+ transporting subunit alpha 3b
chr9_-_42861080 2.53 ENSDART00000193688
titin, tandem duplicate 1
chr8_+_46939391 2.50 ENSDART00000146631
espin
chr22_+_19277361 2.50 ENSDART00000190075
ENSDART00000141097
ENSDART00000136943
si:dkey-21e2.13
chr23_-_26535875 2.49 ENSDART00000135988
si:dkey-205h13.2
chr9_-_23922011 2.42 ENSDART00000145734
collagen, type VI, alpha 3
chr8_+_53423408 2.38 ENSDART00000164792
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr8_-_46894362 2.37 ENSDART00000111124
acyl-CoA thioesterase 7
chr13_+_28675686 2.35 ENSDART00000027213
internexin neuronal intermediate filament protein, alpha a
chr14_-_8890437 2.34 ENSDART00000167242
si:ch73-45o6.2
chr7_+_49865049 2.32 ENSDART00000164165
solute carrier family 1 (glial high affinity glutamate transporter), member 2a
chr23_-_270847 2.30 ENSDART00000191867
ankyrin repeat and sterile alpha motif domain containing 1Aa
chr25_+_37443194 2.27 ENSDART00000163178
ENSDART00000190262
solute carrier family 10, member 3
chr19_+_43563179 2.23 ENSDART00000151478
CD164 sialomucin-like 2
chr17_+_27134806 2.20 ENSDART00000151901
ribosomal protein S6 kinase a, polypeptide 1
chr21_-_28340977 2.15 ENSDART00000141629
neurexin 2a
chr6_+_27667359 2.14 ENSDART00000159624
ENSDART00000049177
RAB6B, member RAS oncogene family a
chr7_+_36539124 2.11 ENSDART00000173653
chromodomain helicase DNA binding protein 9
chr14_-_2355833 2.11 ENSDART00000157677
si:ch73-233f7.6
chr24_-_17023392 2.03 ENSDART00000106058
prostaglandin D2 synthase b, tandem duplicate 2
chr2_+_20332044 2.02 ENSDART00000112131
phospholipid phosphatase related 4a
chr14_+_81919 2.01 ENSDART00000171444
stromal antigen 3
chr7_-_878473 1.99 ENSDART00000173567
si:cabz01080528.1
chr20_-_27864964 1.95 ENSDART00000153311
synapse differentiation inducing 1-like
chr10_-_27049170 1.93 ENSDART00000143451
cornichon family AMPA receptor auxiliary protein 2
chr16_-_17175731 1.93 ENSDART00000183057
opsin 9
chr21_+_30194904 1.91 ENSDART00000137023
ENSDART00000078403
si:ch211-59d17.3
chr7_+_25036188 1.91 ENSDART00000163957
ENSDART00000169749
sb:cb1058
chr19_-_19339285 1.87 ENSDART00000158413
ENSDART00000170479
chondroitin sulfate proteoglycan 5b
chr19_-_1961024 1.85 ENSDART00000108784
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr7_+_67486807 1.85 ENSDART00000159989
copine VII
chr22_+_2254972 1.84 ENSDART00000144906
zinc finger protein 1157
chr5_-_26950374 1.81 ENSDART00000050542
HtrA serine peptidase 4
chr8_+_25351863 1.80 ENSDART00000034092
deoxyribonuclease I-like 1-like
chr18_+_7286788 1.78 ENSDART00000022998
si:ch73-86n2.1
chr8_+_50983551 1.78 ENSDART00000142061
si:dkey-32e23.4
chr23_-_27345425 1.78 ENSDART00000022042
ENSDART00000191870
sodium channel, voltage gated, type VIII, alpha subunit a
chr23_+_2760573 1.77 ENSDART00000129719
DNA topoisomerase I
chr23_+_13375359 1.77 ENSDART00000151947
si:dkey-256k13.2
chr19_-_29887629 1.76 ENSDART00000066123
karyopherin alpha 6 (importin alpha 7)
chr3_-_41795917 1.75 ENSDART00000182662
galectin-related inter-fiber protein
chr10_+_1638876 1.74 ENSDART00000184484
ENSDART00000060946
ENSDART00000181251
small G protein signaling modulator 1b
chr21_+_9666347 1.73 ENSDART00000163853
mitogen-activated protein kinase 10
chr17_-_22062364 1.72 ENSDART00000114470
tau tubulin kinase 1b
chr1_+_34203817 1.70 ENSDART00000191432
ENSDART00000046094
ADP-ribosylation factor-like 6
chr7_-_18730474 1.70 ENSDART00000170374
si:dkey-38l22.2
chr6_-_51101834 1.68 ENSDART00000092493
protein tyrosine phosphatase, receptor type, t
chr23_-_26536055 1.68 ENSDART00000182719
si:dkey-205h13.2
chr23_+_216012 1.67 ENSDART00000181115
ENSDART00000004678
ENSDART00000190439
ENSDART00000189322
si:ch73-162j3.4
chr7_+_23515966 1.67 ENSDART00000186893
ENSDART00000186189
zgc:109889
chr14_+_33413980 1.66 ENSDART00000052780
ENSDART00000124437
ENSDART00000173327
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
chr7_+_25059845 1.63 ENSDART00000077215
protein phosphatase 2, regulatory subunit B', beta
chr3_+_15907458 1.63 ENSDART00000163525
mitogen-activated protein kinase 8 interacting protein 3
chr5_+_27137473 1.62 ENSDART00000181833
unc-5 netrin receptor Db
chr2_-_24996441 1.62 ENSDART00000144795
solute carrier family 35, member G2a
chr3_-_60142530 1.61 ENSDART00000153247
si:ch211-120g10.1
chr19_-_10425140 1.58 ENSDART00000145319
si:ch211-171h4.3
chr7_-_42206720 1.57 ENSDART00000110907
integrin alpha FG-GAP repeat containing 1
chr12_-_3903886 1.57 ENSDART00000184214
ENSDART00000041082
glycerophosphodiester phosphodiesterase domain containing 3b
chr21_+_18353703 1.56 ENSDART00000181396
ENSDART00000166359
si:ch73-287m6.1
chr17_-_37195163 1.53 ENSDART00000108514
additional sex combs like transcriptional regulator 2
chr2_+_55916911 1.52 ENSDART00000189483
ENSDART00000183647
ENSDART00000083470
ataxia, cerebellar, Cayman type b
chr5_-_18513950 1.49 ENSDART00000145878
si:dkey-215k6.1
chr6_-_10780698 1.49 ENSDART00000151714
G protein-coupled receptor 155b
chr23_-_4915118 1.48 ENSDART00000060714
ATPase H+ transporting accessory protein 1a
chr24_-_39771667 1.48 ENSDART00000181867
si:ch211-276f18.2
chr9_+_27411502 1.46 ENSDART00000143994
si:dkey-193n17.9
chr14_-_24110707 1.46 ENSDART00000133522
ENSDART00000123152
cytoplasmic polyadenylation element binding protein 4a
chr13_+_36146415 1.44 ENSDART00000140301
si:ch211-259k16.3
chr12_+_16168342 1.44 ENSDART00000079326
ENSDART00000170024
low density lipoprotein receptor-related protein 2b
chr11_-_41130239 1.44 ENSDART00000173268
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr17_+_20204122 1.43 ENSDART00000078672
gonadotropin-releasing hormone 3
chr3_-_57744323 1.41 ENSDART00000101829
lectin, galactoside-binding, soluble, 3 binding protein b
chr10_+_20113830 1.40 ENSDART00000139722
dematin actin binding protein
chr20_-_4793450 1.40 ENSDART00000053870
galactosylceramidase a
chr18_+_28106139 1.37 ENSDART00000089615
KIAA1549-like b
chr15_-_5563551 1.35 ENSDART00000099520
ATG16 autophagy related 16-like 2 (S. cerevisiae)
chr22_+_1796057 1.35 ENSDART00000170834
zinc finger protein 1179
chr8_+_14792830 1.33 ENSDART00000139972
calcium channel, voltage-dependent, R type, alpha 1E subunit a
chr2_+_3452590 1.33 ENSDART00000153935
cytochrome P450, family 8, subfamily B, polypeptide 2
chr11_+_25112269 1.32 ENSDART00000147546
ndrg family member 3a
chr3_+_15907297 1.32 ENSDART00000139206
mitogen-activated protein kinase 8 interacting protein 3
chr6_-_33685325 1.32 ENSDART00000181883
microtubule associated serine/threonine kinase 2
chr5_+_23118470 1.28 ENSDART00000149893
neurite extension and migration factor a
chr2_+_20331445 1.28 ENSDART00000186880
phospholipid phosphatase related 4a
chr6_-_31348999 1.26 ENSDART00000153734
DnaJ (Hsp40) homolog, subfamily C, member 6
chr5_+_59252701 1.25 ENSDART00000144829
uroplakin 3b
chr10_+_16501699 1.24 ENSDART00000121864
solute carrier family 27 (fatty acid transporter), member 6
chr8_-_25327809 1.24 ENSDART00000137242
EPS8-like 3b
chr15_-_1745408 1.24 ENSDART00000182311
syntaxin 1A (brain)
chr18_+_3332999 1.24 ENSDART00000160857
glycerophosphodiester phosphodiesterase domain containing 4a
chr7_-_57933736 1.23 ENSDART00000142580
ankyrin 2b, neuronal
chr19_-_41991104 1.22 ENSDART00000087055
trio Rho guanine nucleotide exchange factor a
chr7_+_72882446 1.21 ENSDART00000131113
ENSDART00000174223
adhesion G protein-coupled receptor L3
chr1_+_57331813 1.21 ENSDART00000152440
ENSDART00000062841
epsin 3b
chr17_-_50331351 1.20 ENSDART00000149294
otoferlin b
chr2_+_36862473 1.19 ENSDART00000135624
si:dkey-193b15.8
chr12_+_47280839 1.18 ENSDART00000187574
ryanodine receptor 2
chr3_+_22905341 1.17 ENSDART00000111435
histone deacetylase 5
chr17_-_5610514 1.17 ENSDART00000004043
ectonucleotide pyrophosphatase/phosphodiesterase 4
chr13_-_51973562 1.15 ENSDART00000166701
solute carrier family 30, member 10
chr14_+_25464681 1.15 ENSDART00000067500
ENSDART00000187601
si:dkey-280e21.3
chr16_-_29452039 1.13 ENSDART00000148960
si:ch211-113g11.6
chr7_-_24005268 1.13 ENSDART00000173608
si:dkey-183c6.9
chr1_-_45157243 1.11 ENSDART00000131882
mucin, multiple PTS and SEA group, member 1
chr7_+_42206847 1.11 ENSDART00000149250
phosphorylase kinase, beta
chr3_+_431208 1.11 ENSDART00000154296
ENSDART00000048733
si:ch73-308m11.1
si:dkey-167k11.5
chr20_+_27393668 1.11 ENSDART00000005473
transmembrane protein 179
chr3_-_33029426 1.10 ENSDART00000181287

chr21_-_10773344 1.10 ENSDART00000063244
gastrin-releasing peptide
chr9_+_33158191 1.10 ENSDART00000180786
dopey family member 2
chr24_+_32472155 1.09 ENSDART00000098859
neuronal differentiation 6a
chr24_-_982443 1.09 ENSDART00000063151
N-ethylmaleimide-sensitive factor attachment protein, gamma a
chr11_+_43401201 1.08 ENSDART00000190128
vasoactive intestinal peptide b
chr2_-_24369087 1.08 ENSDART00000081237
plasmalemma vesicle associated protein a
chr23_-_29502287 1.08 ENSDART00000141075
ENSDART00000053807
kinesin family member 1B
chr17_-_51938663 1.08 ENSDART00000179784
ergosterol biosynthesis 28 homolog
chr7_+_11543999 1.08 ENSDART00000173676
interleukin 16
chr15_-_36357889 1.07 ENSDART00000156377
si:dkey-23k10.5
chr21_+_9576176 1.07 ENSDART00000161289
ENSDART00000159899
ENSDART00000162834
mitogen-activated protein kinase 10
chr12_-_10300101 1.06 ENSDART00000126428
membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2)
chr3_+_5083407 1.03 ENSDART00000146883
si:ch73-338o16.4
chr14_-_30490763 1.02 ENSDART00000193166
ENSDART00000183471
ENSDART00000087859
mitochondrial calcium uptake family, member 3b
chr11_-_27874116 1.01 ENSDART00000180579
eukaryotic translation initiation factor 4 gamma, 3a
chr4_+_3358383 1.01 ENSDART00000075320
nicotinamide phosphoribosyltransferase a
chr13_-_36050303 1.01 ENSDART00000134955
ENSDART00000139087
legumain
chr5_-_63286077 1.00 ENSDART00000131274
tubulin folding cofactor E-like b
chr18_+_507835 1.00 ENSDART00000189701
neural precursor cell expressed, developmentally down-regulated 4a
chr11_-_37997419 0.99 ENSDART00000102870
solute carrier family 41 (magnesium transporter), member 1
chr25_+_13191615 0.97 ENSDART00000168849
si:ch211-147m6.2
chr10_+_23511816 0.97 ENSDART00000127255
zmp:0000000924
chr22_-_36774219 0.96 ENSDART00000056151
ENSDART00000168711
aminoacylase 1
chr17_-_24564674 0.96 ENSDART00000105435
ENSDART00000135086
ATP-binding cassette, sub-family H, member 1
chr19_+_17385561 0.95 ENSDART00000141397
ENSDART00000143913
ENSDART00000133626
ribosomal protein L15
chr18_-_8579907 0.94 ENSDART00000147284
si:ch211-220f12.1
chr24_-_32408404 0.94 ENSDART00000144157
si:ch211-56a11.2
chr19_-_46088429 0.94 ENSDART00000161385
phosphatidylserine synthase 1b
chr25_+_20077225 0.93 ENSDART00000136543
troponin I4b, tandem duplicate 1
chr4_+_22343093 0.92 ENSDART00000023588
guanylate cyclase activator 1A
chr5_-_21422390 0.90 ENSDART00000144198
teneurin transmembrane protein 1
chr17_+_33415319 0.90 ENSDART00000140805
ENSDART00000025501
ENSDART00000146447
synaptosomal-associated protein 23.1
chr6_+_34512313 0.90 ENSDART00000102554
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr5_-_41049690 0.89 ENSDART00000174936
ENSDART00000135030
PDZ domain containing 2
chr5_-_9625459 0.88 ENSDART00000143347
SH2B adaptor protein 3
chr20_+_20637866 0.88 ENSDART00000060203
ENSDART00000079079
reticulon 1b
chr21_-_2168515 0.88 ENSDART00000165455

chr11_+_30729745 0.86 ENSDART00000103270
solute carrier family 22 (organic anion transporter), member 7a
chr19_+_46372115 0.86 ENSDART00000163935
mediator complex subunit 30
chr1_+_6817292 0.86 ENSDART00000145822
ENSDART00000092118
erb-b2 receptor tyrosine kinase 4a
chr22_-_20379045 0.86 ENSDART00000183511
zinc finger and BTB domain containing 7a
chr7_+_7151832 0.85 ENSDART00000109485
galactose-3-O-sulfotransferase 3
chr8_-_554540 0.83 ENSDART00000163934
Danio rerio uncharacterized LOC100329294 (LOC100329294), mRNA.
chr20_-_45040916 0.83 ENSDART00000190001
kelch-like family member 29
chr21_-_7035599 0.83 ENSDART00000139777
si:ch211-93g21.1
chr3_-_31833266 0.83 ENSDART00000084932
ENSDART00000183617
mitogen-activated protein kinase kinase kinase 3
chr12_+_4900981 0.83 ENSDART00000171507
CD79b molecule, immunoglobulin-associated beta
chr7_+_33172066 0.82 ENSDART00000174013
si:ch211-194p6.12
chr18_-_15559817 0.82 ENSDART00000061681
si:ch211-245j22.3
chr11_+_2506516 0.81 ENSDART00000130886
ENSDART00000189767
si:ch73-190f16.2
chr9_-_18424844 0.80 ENSDART00000154351
ecto-NOX disulfide-thiol exchanger 1
chr9_+_17423941 0.79 ENSDART00000112884
ENSDART00000155233
kelch repeat and BTB (POZ) domain containing 7
chr8_+_51707781 0.79 ENSDART00000129372
kelch-like family member 22
chr11_-_25734417 0.79 ENSDART00000103570
bromodomain and PHD finger containing, 3a
chr2_-_36040820 0.78 ENSDART00000003550
nicotinamide nucleotide adenylyltransferase 2
chr19_-_9867001 0.78 ENSDART00000091695
calcium channel, voltage-dependent, gamma subunit 7a
chr7_+_56889879 0.78 ENSDART00000039810
myosin IXAa
chr3_-_40976288 0.78 ENSDART00000193553
cytochrome P450, family 3, subfamily c, polypeptide 1
chr6_+_4255319 0.78 ENSDART00000170351
neurobeachin-like 1
chr3_+_32403758 0.77 ENSDART00000156982
si:ch211-195b15.8
chr20_+_4793516 0.77 ENSDART00000053875
galectin 8a
chr5_+_65491390 0.77 ENSDART00000159921
si:dkey-21e5.1
chr7_+_18100996 0.76 ENSDART00000055810
zRAB1B, member RAS oncogene family a
chr8_-_4097722 0.76 ENSDART00000135006
cut-like homeobox 2b
chr20_+_14968031 0.76 ENSDART00000151805
ENSDART00000151448
ENSDART00000063874
ENSDART00000190910
vesicle-associated membrane protein 4

Network of associatons between targets according to the STRING database.

First level regulatory network of maff+mafga+mafgb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 8.7 GO:0046485 ether lipid metabolic process(GO:0046485)
0.8 2.3 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.4 1.8 GO:0007638 mechanosensory behavior(GO:0007638)
0.4 1.1 GO:0010312 detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
0.4 2.6 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.4 1.9 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.4 3.7 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.4 1.1 GO:0048917 posterior lateral line ganglion development(GO:0048917)
0.4 1.8 GO:1903146 regulation of mitophagy(GO:1903146)
0.3 2.9 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.3 5.2 GO:0048769 sarcomerogenesis(GO:0048769)
0.3 1.3 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.3 4.8 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.3 1.5 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.3 2.6 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.3 2.7 GO:0098869 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.3 1.1 GO:0070459 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.3 1.3 GO:0039694 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.3 1.3 GO:0032615 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.3 1.0 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.3 1.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.2 1.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.2 1.6 GO:0002931 response to ischemia(GO:0002931)
0.2 1.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.2 1.8 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.2 0.8 GO:0090161 Golgi ribbon formation(GO:0090161)
0.2 1.9 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.2 1.4 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.2 1.2 GO:0050820 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.2 2.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.2 0.8 GO:0007624 ultradian rhythm(GO:0007624)
0.2 0.5 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.2 0.8 GO:0048025 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 1.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 2.8 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 1.5 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.1 1.5 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 1.5 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 2.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 2.0 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.1 2.4 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 1.8 GO:0006265 DNA topological change(GO:0006265)
0.1 0.6 GO:0032218 riboflavin transport(GO:0032218)
0.1 1.2 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 0.7 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.1 0.9 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 5.0 GO:0007602 phototransduction(GO:0007602)
0.1 1.0 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 3.0 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.6 GO:0070207 protein homotrimerization(GO:0070207)
0.1 0.5 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.6 GO:0010460 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.1 1.3 GO:0072028 nephron morphogenesis(GO:0072028)
0.1 1.6 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 0.7 GO:0003422 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.1 1.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 1.6 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 1.6 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 7.8 GO:0070509 calcium ion import(GO:0070509)
0.1 2.1 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 0.4 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.1 1.1 GO:0050930 regulation of positive chemotaxis(GO:0050926) positive regulation of positive chemotaxis(GO:0050927) induction of positive chemotaxis(GO:0050930)
0.1 0.9 GO:0042407 cristae formation(GO:0042407)
0.1 1.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 4.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.8 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 0.8 GO:0009435 NAD biosynthetic process(GO:0009435)
0.1 1.4 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 1.6 GO:0000187 activation of MAPK activity(GO:0000187)
0.1 0.5 GO:0042214 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 0.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 1.0 GO:0098508 endothelial to hematopoietic transition(GO:0098508)
0.0 0.6 GO:0099638 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.4 GO:0046457 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.4 GO:0031179 peptide modification(GO:0031179)
0.0 0.8 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.5 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 1.7 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.1 GO:0033212 iron assimilation(GO:0033212)
0.0 0.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.7 GO:0055078 sodium ion homeostasis(GO:0055078)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 3.3 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.9 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 2.8 GO:0007254 JNK cascade(GO:0007254)
0.0 0.8 GO:0030183 B cell differentiation(GO:0030183)
0.0 1.2 GO:0072114 pronephros morphogenesis(GO:0072114)
0.0 2.0 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.6 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.0 1.2 GO:0015908 fatty acid transport(GO:0015908)
0.0 0.3 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 1.8 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.4 GO:0030819 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 3.6 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 1.5 GO:0006885 regulation of pH(GO:0006885) regulation of cellular pH(GO:0030641)
0.0 0.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.3 GO:0030431 sleep(GO:0030431)
0.0 0.9 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.2 GO:0044211 CTP salvage(GO:0044211)
0.0 0.5 GO:0051639 actin filament network formation(GO:0051639)
0.0 1.3 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 1.7 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108)
0.0 0.2 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 1.1 GO:0050922 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of chemotaxis(GO:0050922) negative regulation of axon guidance(GO:1902668)
0.0 0.3 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.0 0.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.7 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.2 GO:0070193 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0 0.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 1.1 GO:0051017 actin filament bundle assembly(GO:0051017)
0.0 0.1 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.0 0.9 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 0.6 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 0.2 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 1.7 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 1.1 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 1.2 GO:0017157 regulation of exocytosis(GO:0017157)
0.0 0.4 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 2.4 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.0 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.1 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.1 GO:0009313 oligosaccharide catabolic process(GO:0009313)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0044316 cone cell pedicle(GO:0044316)
0.5 2.3 GO:0005883 neurofilament(GO:0005883)
0.3 1.0 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.3 4.8 GO:0031209 SCAR complex(GO:0031209)
0.2 1.5 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.2 1.5 GO:0035517 PR-DUB complex(GO:0035517)
0.2 0.8 GO:0019815 B cell receptor complex(GO:0019815)
0.2 0.7 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.2 1.2 GO:0030315 T-tubule(GO:0030315)
0.2 2.0 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 1.4 GO:0061617 MICOS complex(GO:0061617)
0.1 1.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.8 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 7.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 4.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 2.8 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.7 GO:0061700 GATOR2 complex(GO:0061700)
0.1 2.0 GO:0008278 cohesin complex(GO:0008278)
0.1 3.6 GO:0005861 troponin complex(GO:0005861)
0.1 1.0 GO:1990246 uniplex complex(GO:1990246)
0.1 1.7 GO:0060170 ciliary membrane(GO:0060170)
0.1 4.5 GO:0031201 SNARE complex(GO:0031201)
0.1 1.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 1.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.8 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.7 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.5 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 2.7 GO:0005814 centriole(GO:0005814)
0.0 1.5 GO:0030426 growth cone(GO:0030426)
0.0 1.1 GO:0043204 perikaryon(GO:0043204)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 2.4 GO:0005581 collagen trimer(GO:0005581)
0.0 2.7 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.7 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.2 GO:0016324 apical plasma membrane(GO:0016324)
0.0 2.9 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 0.7 GO:0031941 filamentous actin(GO:0031941)
0.0 1.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.2 GO:0005871 kinesin complex(GO:0005871)
0.0 0.1 GO:0097225 sperm midpiece(GO:0097225)
0.0 2.3 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 8.4 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.5 GO:0005811 lipid particle(GO:0005811)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 8.7 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.6 2.9 GO:0008432 JUN kinase binding(GO:0008432)
0.6 1.8 GO:0048030 disaccharide binding(GO:0048030)
0.5 4.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.5 1.4 GO:0005183 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.4 1.3 GO:0008397 sterol 12-alpha-hydroxylase activity(GO:0008397)
0.4 2.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.3 2.7 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.3 2.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.3 1.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.3 2.8 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.3 2.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.3 1.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.3 3.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 3.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.2 2.0 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.2 6.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 0.6 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.2 2.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 1.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.2 1.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 1.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.2 1.5 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 1.5 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.1 1.8 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 3.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 2.6 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.9 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 0.6 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 2.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.9 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 1.8 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 5.0 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.6 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 1.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.7 GO:0070728 leucine binding(GO:0070728)
0.1 1.6 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 2.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.9 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 1.0 GO:0004046 aminoacylase activity(GO:0004046)
0.1 1.6 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 1.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.2 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 1.0 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 1.6 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 1.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.6 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 1.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.8 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 0.7 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 0.6 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.2 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.6 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 1.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.2 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.1 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.8 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 0.2 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.5 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 0.8 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0030273 melanin-concentrating hormone receptor activity(GO:0030273)
0.0 2.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:0019202 amino acid kinase activity(GO:0019202)
0.0 0.8 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.4 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160) ionotropic glutamate receptor binding(GO:0035255)
0.0 0.8 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 2.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 8.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 1.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 4.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.7 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 2.1 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0043295 glutathione binding(GO:0043295)
0.0 0.5 GO:0031267 small GTPase binding(GO:0031267)
0.0 1.4 GO:0042562 hormone binding(GO:0042562)
0.0 2.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.7 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.6 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 3.5 GO:0015293 symporter activity(GO:0015293)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 1.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 2.1 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0001607 neuromedin U receptor activity(GO:0001607)
0.0 0.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.3 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.7 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.1 GO:0001972 retinoic acid binding(GO:0001972)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.7 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 2.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 2.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.4 NABA COLLAGENS Genes encoding collagen proteins
0.1 0.9 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.9 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.2 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.9 PID EPO PATHWAY EPO signaling pathway
0.0 2.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 2.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.3 2.8 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 2.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.2 2.2 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.2 2.0 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 2.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.0 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 2.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 0.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 2.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 1.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.5 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation