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PRJEB1986: zebrafish developmental stages transcriptome

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Results for mafaa

Z-value: 0.50

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Transcription factors associated with mafaa

Gene Symbol Gene ID Gene Info
ENSDARG00000044155 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Aa

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mafaadr11_v1_chr6_-_32703317_327033170.019.8e-01Click!

Activity profile of mafaa motif

Sorted Z-values of mafaa motif

Promoter Log-likelihood Transcript Gene Gene Info
chr24_-_41312459 0.99 ENSDART00000041349
crystallin, gamma N2
chr16_+_1353894 0.80 ENSDART00000148426
cugbp, Elav-like family member 3b
chr22_-_15280638 0.70 ENSDART00000063008
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr23_-_21453614 0.68 ENSDART00000079274
hairy-related 4, tandem duplicate 1
chr1_+_59090972 0.67 ENSDART00000171497
microfibril associated protein 4
chr1_+_59090743 0.66 ENSDART00000100199
microfibril associated protein 4
chr23_+_3538463 0.64 ENSDART00000172758
si:dkey-9l20.3
chr12_-_47558276 0.63 ENSDART00000160260
gremlin 2, DAN family BMP antagonist b
chr23_+_21459263 0.59 ENSDART00000104209
hairy-related 4, tandem duplicate 3
chr11_+_12719944 0.58 ENSDART00000054837
ENSDART00000144954
adaptor-related protein complex 1, sigma 2 subunit
chr10_+_21780250 0.55 ENSDART00000183782
protocadherin 1 gamma 9
chr1_+_59090583 0.55 ENSDART00000150658
microfibril associated protein 4
chr25_-_27842654 0.53 ENSDART00000154852
ENSDART00000156906
ankyrin repeat and SOCS box containing 15a
chr19_-_28788466 0.52 ENSDART00000151793
SRY (sex determining region Y)-box 4a
chr11_-_36263886 0.52 ENSDART00000140397
nuclear transcription factor Y, alpha
chr1_-_625875 0.38 ENSDART00000167331
amyloid beta (A4) precursor protein a
chr1_-_26045007 0.36 ENSDART00000129259
G patch domain and ankyrin repeats 1
chr25_+_3217419 0.36 ENSDART00000104859
RCC1 domain containing 1
chr14_-_17588345 0.35 ENSDART00000143486
selenoprotein T, 2
chr6_-_39313027 0.34 ENSDART00000012644
keratin 4
chr20_+_54323218 0.33 ENSDART00000191096

chr13_-_28272299 0.33 ENSDART00000006393
T cell leukemia homeobox 1
chr19_+_29798064 0.30 ENSDART00000167803
ENSDART00000051804
MARCKS-like 1b
chr8_-_2591654 0.30 ENSDART00000049109
SET nuclear proto-oncogene a
chr6_-_33913184 0.29 ENSDART00000146373
nuclear autoantigenic sperm protein (histone-binding)
chr22_-_775776 0.28 ENSDART00000149749
retinoblastoma binding protein 5
chr19_-_3777217 0.27 ENSDART00000160510
si:dkey-206d17.15
chr8_+_50534948 0.26 ENSDART00000174435
phosphatidylethanolamine binding protein 4
chr14_-_30490763 0.25 ENSDART00000193166
ENSDART00000183471
ENSDART00000087859
mitochondrial calcium uptake family, member 3b
chr16_-_27676123 0.25 ENSDART00000180804
transforming growth factor beta regulator 4
chr12_+_30789611 0.25 ENSDART00000181501
aldehyde dehydrogenase 18 family, member A1
chr22_+_635813 0.25 ENSDART00000179067

chr16_-_46567344 0.25 ENSDART00000127721
si:dkey-152b24.7
chr18_-_48745517 0.25 ENSDART00000097259
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr20_-_23440955 0.24 ENSDART00000153386
solute carrier family 10, member 4
chr23_+_42338325 0.23 ENSDART00000169660
cytochrome P450, family 2, subfamily AA, polypeptide 7
chr4_+_19700308 0.22 ENSDART00000027919
paired box 4
chr25_-_3217115 0.22 ENSDART00000032390
general transcription factor IIH, polypeptide 1
chr17_-_48915427 0.20 ENSDART00000054781
galectin 8b
chr5_-_35137365 0.20 ENSDART00000141218
FCH domain only 2
chr20_-_39391833 0.20 ENSDART00000135149
si:dkey-217m5.8
chr13_+_4671698 0.20 ENSDART00000164617
ENSDART00000128494
ENSDART00000165776
phospholipase A2, group XIIB
chr13_-_50463938 0.20 ENSDART00000083857
cyclin J
chr21_-_13225402 0.19 ENSDART00000080347
WD repeat domain 34
chr8_-_3336273 0.18 ENSDART00000081160
zgc:173737
chr22_+_10606863 0.18 ENSDART00000147975
RAD54 like 2
chr15_-_17138640 0.17 ENSDART00000080777
mitochondrial ribosomal protein L28
chr7_+_6969909 0.17 ENSDART00000189886
actinin alpha 3b
chr22_+_21305682 0.17 ENSDART00000023521
outer dense fiber of sperm tails 3-like 2
chr21_-_17037907 0.16 ENSDART00000101263
ubiquitin-conjugating enzyme E2G 1b (UBC7 homolog, yeast)
chr13_+_6295173 0.16 ENSDART00000163855
angiopoietin 2a
chr21_-_1642739 0.16 ENSDART00000151118
zgc:152948
chr20_-_39219537 0.15 ENSDART00000005764
cytochrome P450, family 39, subfamily A, polypeptide 1
chr24_+_6353394 0.15 ENSDART00000165118

chr7_+_41421998 0.14 ENSDART00000083967
chondroitin polymerizing factor 2
chr3_+_8826905 0.14 ENSDART00000167474
ENSDART00000168088
si:dkeyp-30d6.2
chr8_-_14052349 0.13 ENSDART00000135811
ATPase plasma membrane Ca2+ transporting 3a
chr5_-_33230794 0.13 ENSDART00000144273
KN motif and ankyrin repeat domains 1b
chr2_+_38161318 0.13 ENSDART00000044264
matrix metallopeptidase 14b (membrane-inserted)
chr25_-_21156678 0.13 ENSDART00000156257
WNK lysine deficient protein kinase 1a
chr12_+_12789853 0.10 ENSDART00000064839
glutamate receptor, ionotropic, delta 1b
chr3_-_10677890 0.10 ENSDART00000155382
ENSDART00000171319
si:ch1073-144j5.2
chr24_+_37709191 0.10 ENSDART00000066558
2,4-dienoyl CoA reductase 2, peroxisomal
chr15_+_7086327 0.10 ENSDART00000114560
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr10_-_2788668 0.10 ENSDART00000131749
ENSDART00000124356
ENSDART00000085031
ash2 (absent, small, or homeotic)-like (Drosophila)
chr17_-_20202725 0.10 ENSDART00000133650
ecdysoneless homolog (Drosophila)
chr4_-_72468168 0.09 ENSDART00000182995
ENSDART00000174067

chr1_-_16676177 0.09 ENSDART00000159038
FSHD region gene 1
chr2_+_36828243 0.09 ENSDART00000135754
ENSDART00000140474
nardilysin a (N-arginine dibasic convertase)
chr12_-_19119176 0.08 ENSDART00000149180
aconitase 2, mitochondrial
chr21_+_19347655 0.08 ENSDART00000093155
heparanase
chr8_+_52479026 0.08 ENSDART00000162885
Danio rerio gamma-glutamyl hydrolase (LOC553228), mRNA.
chr9_-_1639884 0.08 ENSDART00000062850
ENSDART00000150947
alkylglycerone phosphate synthase
chr7_-_40578733 0.07 ENSDART00000173926
ENSDART00000010035
DnaJ (Hsp40) homolog, subfamily B, member 6b
chr10_-_57270 0.06 ENSDART00000058411
holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
chr5_-_40510397 0.06 ENSDART00000146237
ENSDART00000051065
follistatin a
chr12_-_11649690 0.06 ENSDART00000149713
BTB (POZ) domain containing 16
chr3_+_26322596 0.06 ENSDART00000172700
si:ch211-156b7.5
chr25_-_24240797 0.06 ENSDART00000132790
SPT2 chromatin protein domain containing 1
chr25_+_459901 0.05 ENSDART00000154895
protogenin homolog b (Gallus gallus)
chr22_+_5574952 0.05 ENSDART00000171774
zgc:171566
chr5_-_23795688 0.05 ENSDART00000099084
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4
chr24_+_80653 0.04 ENSDART00000158473
ENSDART00000129135
reversion-inducing-cysteine-rich protein with kazal motifs
chr6_-_13709591 0.04 ENSDART00000151771
chondroitin polymerizing factor b
chr7_-_7493758 0.04 ENSDART00000036703
prefoldin subunit 2
chr7_+_27603211 0.04 ENSDART00000148782
cytochrome P450, family 2, subfamily R, polypeptide 1
chr22_+_12477996 0.04 ENSDART00000177704

chr2_-_37896965 0.03 ENSDART00000129852
hexose-binding lectin 1
chr19_-_42566527 0.03 ENSDART00000147818
ENSDART00000142135
si:dkey-228a15.1
chr6_-_25371196 0.03 ENSDART00000187291
zgc:153916
chr4_-_50926767 0.03 ENSDART00000183430
si:ch211-208f21.3
chr15_-_45110011 0.02 ENSDART00000182047
ENSDART00000188662

chr23_+_42652877 0.02 ENSDART00000035654
cytochrome P450, family 2, subfamily AE, polypeptide 1
chr4_-_8030583 0.02 ENSDART00000113628
si:ch211-240l19.8
chr20_-_22476255 0.02 ENSDART00000103510
platelet-derived growth factor receptor, alpha polypeptide
chr16_+_42465518 0.02 ENSDART00000058699
si:ch211-215k15.4
chr8_-_21071476 0.01 ENSDART00000184184
ENSDART00000100288
zgc:112962
chr6_-_131401 0.00 ENSDART00000151251
si:zfos-323e3.4
chr4_+_9911534 0.00 ENSDART00000109452
SET binding factor 1
chr18_-_26126258 0.00 ENSDART00000145875
ankyrin repeat domain 34C

Network of associatons between targets according to the STRING database.

First level regulatory network of mafaa

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 1.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.3 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 1.3 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.2 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.3 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.0 0.2 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.1 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.0 0.2 GO:0006699 bile acid biosynthetic process(GO:0006699) bile acid metabolic process(GO:0008206)
0.0 0.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.5 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:1903963 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328) arachidonate transport(GO:1903963)
0.0 0.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.1 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.0 0.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.0 GO:1905048 regulation of metallopeptidase activity(GO:1905048)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:1990246 uniplex complex(GO:1990246)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.6 GO:0036122 BMP binding(GO:0036122)
0.1 1.9 GO:0003823 antigen binding(GO:0003823)
0.0 0.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.3 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0003994 aconitate hydratase activity(GO:0003994)
0.0 0.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 1.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.6 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.1 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis