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PRJEB1986: zebrafish developmental stages transcriptome

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Results for lhx3+lhx4

Z-value: 0.89

Motif logo

Transcription factors associated with lhx3+lhx4

Gene Symbol Gene ID Gene Info
ENSDARG00000003803 LIM homeobox 3
ENSDARG00000039458 LIM homeobox 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX3dr11_v1_chr5_+_71802014_718020140.789.1e-05Click!
lhx4dr11_v1_chr8_-_14484599_144845990.408.8e-02Click!

Activity profile of lhx3+lhx4 motif

Sorted Z-values of lhx3+lhx4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_34641237 5.90 ENSDART00000133996
short stature homeobox
chr9_-_22099536 4.87 ENSDART00000101923

chr25_+_31276842 3.77 ENSDART00000187238
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr25_+_31227747 3.61 ENSDART00000033872
troponin I type 2a (skeletal, fast), tandem duplicate 1
chr9_+_2574122 2.60 ENSDART00000166326
ENSDART00000191822
si:ch73-167c12.2
chr14_+_46313396 2.55 ENSDART00000047525
crystallin, beta A1, like 1
chr11_+_24002503 2.46 ENSDART00000164702
chitinase, acidic.2
chr11_+_24001993 2.32 ENSDART00000168215
chitinase, acidic.2
chr21_-_20939488 2.32 ENSDART00000039043
regulator of G protein signaling 7 binding protein b
chr20_+_4060839 2.29 ENSDART00000178565
tripartite motif containing 67
chr15_-_37850969 2.17 ENSDART00000031418
heat shock cognate 70
chr5_-_41494831 2.15 ENSDART00000051081
eukaryotic translation elongation factor 2, like 2
chr3_+_21225750 2.03 ENSDART00000139213
zgc:153968
chr5_+_2815021 1.99 ENSDART00000020472
4-hydroxyphenylpyruvate dioxygenase a
chr2_+_2223837 1.97 ENSDART00000101038
ENSDART00000129354
transmembrane inner ear
chr7_+_24573721 1.91 ENSDART00000173938
ENSDART00000173681
si:dkeyp-75h12.7
chr15_-_46779934 1.87 ENSDART00000085136
chloride channel 2c
chr13_-_29421331 1.87 ENSDART00000150228
choline O-acetyltransferase a
chr10_-_27049170 1.77 ENSDART00000143451
cornichon family AMPA receptor auxiliary protein 2
chr6_+_7444899 1.74 ENSDART00000053775
ADP-ribosylation factor 3b
chr16_+_46111849 1.72 ENSDART00000172232
synaptic vesicle glycoprotein 2A
chr15_-_44601331 1.69 ENSDART00000161514
zgc:165508
chr1_-_5455498 1.66 ENSDART00000040368
ENSDART00000114035
motor neuron and pancreas homeobox 2b
chr23_-_39666519 1.64 ENSDART00000110868
ENSDART00000190961
von Willebrand factor A domain containing 1
chr9_-_49493305 1.62 ENSDART00000148707
ENSDART00000148561
xin actin binding repeat containing 2b
chr3_+_29714775 1.60 ENSDART00000041388
calcium channel, voltage-dependent, gamma subunit 2a
chr7_-_66868543 1.55 ENSDART00000149680
adenosine monophosphate deaminase 3a
chr17_-_31483469 1.51 ENSDART00000062907
ENSDART00000061547
leukocyte receptor tyrosine kinase
chr18_-_38088099 1.48 ENSDART00000146120
leucine zipper protein 2
chr16_-_28856112 1.41 ENSDART00000078543
synaptotagmin XIb
chr4_+_9669717 1.40 ENSDART00000004604
si:dkey-153k10.9
chr5_+_71802014 1.39 ENSDART00000124939
ENSDART00000097164
LIM homeobox 3
chr17_+_13664442 1.39 ENSDART00000171689
leucine rich repeat and fibronectin type III domain containing 5a
chr4_-_4387012 1.37 ENSDART00000191836
Danio rerio U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1-like (LOC100331497), mRNA.
chr25_+_13406069 1.36 ENSDART00000010495
zinc and ring finger 1
chr9_+_54039006 1.35 ENSDART00000112441
toll-like receptor 7
chr8_-_34052019 1.34 ENSDART00000040126
ENSDART00000159208
ENSDART00000048994
ENSDART00000098822
pre-B-cell leukemia homeobox 3b
chr7_-_71829649 1.32 ENSDART00000160449
calcium channel, voltage-dependent, beta 2a
chr20_+_41664350 1.30 ENSDART00000186247
family with sequence similarity 184, member A
chr24_-_7697274 1.29 ENSDART00000186077
synaptotagmin Vb
chr17_+_16564921 1.27 ENSDART00000151904
forkhead box N3
chr1_-_21901589 1.26 ENSDART00000140553
FERM and PDZ domain containing 1a
chr15_-_46718759 1.24 ENSDART00000085926
ENSDART00000154577
zgc:162872
chr22_-_21897203 1.24 ENSDART00000158501
ENSDART00000105566
ENSDART00000136795
guanine nucleotide binding protein (G protein), alpha 11a (Gq class)
chr3_-_48716422 1.23 ENSDART00000164979
si:ch211-114m9.1
chr20_+_52389858 1.23 ENSDART00000185863
ENSDART00000166651
Rho GTPase activating protein 39
chr18_+_1703984 1.23 ENSDART00000114010
SLIT and NTRK-like family, member 3a
chr10_+_45089820 1.22 ENSDART00000175481
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr10_+_22381802 1.21 ENSDART00000112484
neuroligin 2b
chr16_-_27749172 1.20 ENSDART00000145198
STEAP family member 4
chr9_+_38481780 1.19 ENSDART00000087241
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr17_+_50524573 1.18 ENSDART00000187974

chr18_+_21408794 1.18 ENSDART00000140161
N-terminal EF-hand calcium binding protein 2
chr23_-_30954738 1.15 ENSDART00000188996
oxysterol binding protein-like 2a
chr1_+_33969015 1.15 ENSDART00000042984
ENSDART00000146530
eph receptor A6
chr1_-_19215336 1.14 ENSDART00000162949
ENSDART00000170680
protein tyrosine phosphatase, receptor type, D, b
chr23_+_16638639 1.14 ENSDART00000143545
syntaphilin b
chr6_-_51386656 1.13 ENSDART00000154732
ENSDART00000177990
ENSDART00000184928
ENSDART00000180197
protein tyrosine phosphatase, receptor type, t
chr18_+_924949 1.12 ENSDART00000170888
ENSDART00000193163
pyruvate kinase M1/2a
chr19_+_5480327 1.12 ENSDART00000148794
junction plakoglobin b
chr20_+_32523576 1.11 ENSDART00000147319
Scm polycomb group protein like 4
chr14_-_4556896 1.11 ENSDART00000044678
ENSDART00000192863
gamma-aminobutyric acid type A receptor alpha2 subunit
chr11_+_30663300 1.10 ENSDART00000161662
tau tubulin kinase 1a
chr20_+_32552912 1.08 ENSDART00000009691
Scm polycomb group protein like 4
chr8_+_10561922 1.06 ENSDART00000133348
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5-like
chr25_-_4146947 1.05 ENSDART00000129268
fatty acid desaturase 2
chr3_+_7808459 1.05 ENSDART00000162374
hook microtubule-tethering protein 2
chr7_+_29954709 1.05 ENSDART00000173904
alpha-tropomyosin
chr10_+_26972755 1.05 ENSDART00000042162
transmembrane 7 superfamily member 2
chr7_+_25033924 1.05 ENSDART00000170873
sb:cb1058
chr23_-_306796 1.05 ENSDART00000143125
ankyrin repeat and sterile alpha motif domain containing 1Aa
chr8_+_26141680 1.04 ENSDART00000078334
cadherin, EGF LAG seven-pass G-type receptor 3
chr20_-_5291012 1.02 ENSDART00000122892
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 3
chr21_+_45841731 1.02 ENSDART00000038657
fatty acid hydroxylase domain containing 2
chr8_-_34051548 1.02 ENSDART00000105204
pre-B-cell leukemia homeobox 3b
chr19_+_43297546 1.01 ENSDART00000168002
lysosomal protein transmembrane 5
chr10_-_2524297 1.01 ENSDART00000192475

chr14_-_413273 1.00 ENSDART00000163976
ENSDART00000179907
FAT atypical cadherin 4
chr22_-_26865181 1.00 ENSDART00000138311
heme oxygenase 2a
chr9_+_54290896 1.00 ENSDART00000149175
POU class 4 homeobox 3
chr6_+_39905021 0.99 ENSDART00000064904
endonuclease, polyU-specific
chr14_-_2933185 0.99 ENSDART00000161677
ENSDART00000162446
ENSDART00000109378
si:dkey-201i24.6
chr20_-_2949028 0.97 ENSDART00000104667
ENSDART00000193151
ENSDART00000131946
cyclin-dependent kinase 19
chr23_-_32100106 0.96 ENSDART00000044658
LETM1 domain containing 1
chr2_+_20430366 0.95 ENSDART00000155108
si:ch211-153l6.6
chr8_+_52637507 0.93 ENSDART00000163830
si:dkey-90l8.3
chr23_-_18024543 0.93 ENSDART00000139695
peptidase M20 domain containing 1, tandem duplicate 1
chr17_+_15433518 0.92 ENSDART00000026180
fatty acid binding protein 7, brain, a
chr8_+_8459192 0.91 ENSDART00000140942
ENSDART00000014939
catechol-O-methyltransferase a
chr3_-_59297532 0.91 ENSDART00000187991

chr4_-_18309917 0.89 ENSDART00000189084
plexin C1
chr17_+_38476300 0.89 ENSDART00000123298
StAR-related lipid transfer (START) domain containing 9
chr2_-_1548330 0.89 ENSDART00000082155
ENSDART00000108481
ENSDART00000111272
Dab, reelin signal transducer, homolog 1b (Drosophila)
chr6_+_51773873 0.87 ENSDART00000156516
transmembrane protein 74B
chr16_-_38118003 0.87 ENSDART00000058667
si:dkey-23o4.6
chr22_-_31517300 0.86 ENSDART00000164799
solute carrier family 6 (neurotransmitter transporter), member 6b
chr6_-_28980756 0.86 ENSDART00000014661
glomulin, FKBP associated protein b
chr17_+_15433671 0.86 ENSDART00000149568
fatty acid binding protein 7, brain, a
chr24_+_13316737 0.85 ENSDART00000191658
somatomedin B and thrombospondin type 1 domain containing
chr7_-_28148310 0.85 ENSDART00000044208
LIM domain only 1
chr9_+_24159280 0.85 ENSDART00000184624
ENSDART00000178422
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2a
chr3_+_32553714 0.84 ENSDART00000165638
paired box 10
chr12_-_48006835 0.84 ENSDART00000108989
ADAM metallopeptidase with thrombospondin type 1 motif, 14
chr6_-_11768198 0.83 ENSDART00000183463
membrane-associated ring finger (C3HC4) 7
chr9_+_33009284 0.83 ENSDART00000036926
VANGL planar cell polarity protein 1
chr16_-_45178430 0.83 ENSDART00000165186
si:dkey-33i11.9
chr5_+_4436405 0.83 ENSDART00000167969

chr19_-_5865766 0.83 ENSDART00000191007

chr7_+_10701938 0.82 ENSDART00000158162
aryl-hydrocarbon receptor nuclear translocator 2
chr21_-_14811058 0.81 ENSDART00000143100
phosphohistidine phosphatase 1
chr3_-_47876427 0.81 ENSDART00000180844
ENSDART00000124480
adhesion G protein-coupled receptor L1a
chr18_+_39487486 0.80 ENSDART00000126978
acyl-CoA dehydrogenase long chain
chr1_+_6862917 0.80 ENSDART00000182953
erb-b2 receptor tyrosine kinase 4a
chr7_+_17229980 0.80 ENSDART00000184910
solute carrier family 6 (neurotransmitter transporter), member 5
chr20_+_34933183 0.80 ENSDART00000062738
synaptosomal-associated protein, 25a
chr13_+_1089942 0.80 ENSDART00000054322
cannabinoid receptor interacting protein 1b
chr9_-_48407408 0.80 ENSDART00000058248
zgc:172182
chr2_+_37227011 0.79 ENSDART00000126587
ENSDART00000084958
sterile alpha motif domain containing 7
chr1_+_38858399 0.79 ENSDART00000165454

chr12_-_26383242 0.79 ENSDART00000152941
ubiquitin specific peptidase 54b
chr6_+_52350443 0.79 ENSDART00000151612
ENSDART00000151349
si:ch211-239j9.1
chr18_+_15644559 0.79 ENSDART00000061794
nuclear receptor subfamily 1, group H, member 4
chr13_-_29420885 0.78 ENSDART00000024225
choline O-acetyltransferase a
chr14_-_858985 0.78 ENSDART00000148687
ENSDART00000149375
solute carrier family 34 (type II sodium/phosphate cotransporter), member 1a
chr21_+_3093419 0.78 ENSDART00000162520
SHC adaptor protein 3
chr16_+_51326237 0.78 ENSDART00000168525

chr12_-_6880694 0.78 ENSDART00000171846
protocadherin-related 15b
chr17_-_45040813 0.77 ENSDART00000075514
ectonucleoside triphosphate diphosphohydrolase 5a
chr21_-_2814709 0.77 ENSDART00000097664
semaphorin 4D
chr4_-_2219705 0.76 ENSDART00000131046
si:ch73-278m9.1
chr14_-_17306261 0.76 ENSDART00000191747
janus kinase and microtubule interacting protein 1
chr12_+_1139690 0.75 ENSDART00000160442

chr22_-_31060579 0.75 ENSDART00000182376
cullin-associated and neddylation-dissociated 2 (putative)
chr9_+_27339505 0.75 ENSDART00000011822
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr9_+_29643036 0.75 ENSDART00000023210
ENSDART00000175160
tripartite motif containing 13
chr8_+_43340995 0.75 ENSDART00000038566
refilin A
chr8_-_39952727 0.74 ENSDART00000181310
calcium binding protein 1a
chr15_+_9327252 0.73 ENSDART00000144381
sarcoglycan, gamma
chr1_-_34750169 0.72 ENSDART00000149380
si:dkey-151m22.8
chr2_+_29491314 0.72 ENSDART00000181774
discs, large (Drosophila) homolog-associated protein 1a
chr5_-_21422390 0.71 ENSDART00000144198
teneurin transmembrane protein 1
chr10_-_43404027 0.71 ENSDART00000086227
EGF-like repeats and discoidin I-like domains 3b
chr2_+_42072231 0.70 ENSDART00000084517
valosin containing protein (p97)/p47 complex interacting protein 1
chr12_+_1000323 0.70 ENSDART00000054363
si:ch1073-272o11.3
chr23_-_20051369 0.70 ENSDART00000049836
biglycan b
chr6_-_57539141 0.69 ENSDART00000156967
itchy E3 ubiquitin protein ligase a
chr6_-_43677125 0.69 ENSDART00000150128
forkhead box P1b
chr11_+_28476298 0.69 ENSDART00000122319
leucine rich repeat containing 38b
chr9_+_45227028 0.69 ENSDART00000185579
adenosine deaminase, RNA-specific, B1b
chr7_+_31891110 0.69 ENSDART00000173883
myosin binding protein C, cardiac
chr21_-_275377 0.68 ENSDART00000157509
relaxin 1
chr10_-_5844915 0.68 ENSDART00000185929
ankyrin repeat domain 55
chr3_-_56456527 0.68 ENSDART00000156553
cytohesin 1a
chr21_+_21195487 0.67 ENSDART00000181746
ENSDART00000184832
RPTOR independent companion of MTOR, complex 2b
chr10_-_5847655 0.66 ENSDART00000192773
ankyrin repeat domain 55
chr18_+_19972853 0.66 ENSDART00000180071
SKI family transcriptional corepressor 1b
chr1_-_22757145 0.66 ENSDART00000134719
prominin 1 b
chr5_+_69747417 0.65 ENSDART00000153717
si:ch211-275j6.5
chr7_+_66822229 0.65 ENSDART00000112109
lymphatic vessel endothelial hyaluronic receptor 1a
chr19_-_41371978 0.65 ENSDART00000166063
ENSDART00000170343
solute carrier family 25 (aspartate/glutamate carrier), member 13
chr11_-_25733910 0.65 ENSDART00000171935
bromodomain and PHD finger containing, 3a
chr7_+_13382852 0.64 ENSDART00000166318
diacylglycerol lipase, alpha
chr4_-_5019113 0.64 ENSDART00000189321
ENSDART00000081990
striatin interacting protein 2
chr6_-_56103718 0.64 ENSDART00000191002
glucosaminyl (N-acetyl) transferase family member 7
chr11_+_40812590 0.63 ENSDART00000186690
ERBB receptor feedback inhibitor 1a
chr15_+_34592215 0.63 ENSDART00000099776
tetraspanin 13a
chr10_-_17083180 0.63 ENSDART00000170083
family with sequence similarity 166, member B
chr7_-_11596450 0.62 ENSDART00000173863
StAR-related lipid transfer (START) domain containing 5
chr21_+_27278120 0.62 ENSDART00000193882
si:dkey-175m17.7
chr2_-_9059955 0.62 ENSDART00000022768
adenylate kinase 5
chr17_+_43623598 0.62 ENSDART00000154138
zinc finger protein 365
chr17_+_28533102 0.61 ENSDART00000156218
MAM domain containing glycosylphosphatidylinositol anchor 2a
chr25_+_7671640 0.61 ENSDART00000145367
potassium inwardly-rectifying channel, subfamily J, member 11, like
chr3_-_32337653 0.61 ENSDART00000156918
ENSDART00000156551
si:dkey-16p21.8
chr22_-_14739491 0.61 ENSDART00000133385
low density lipoprotein receptor-related protein 1Ba
chr7_+_71547747 0.61 ENSDART00000180869
adenylate cyclase activating polypeptide 1a
chr2_+_38554260 0.60 ENSDART00000171527
cadherin 24, type 2b
chr20_-_9462433 0.60 ENSDART00000152674
ENSDART00000040557
zgc:101840
chr4_+_12111154 0.60 ENSDART00000036779
transmembrane protein 178B
chr6_+_23887314 0.59 ENSDART00000163188
zinc finger protein 648
chr14_-_45512807 0.59 ENSDART00000173172
si:ch211-114c17.1
chr21_-_39327223 0.59 ENSDART00000115097
apoptosis-inducing factor, mitochondrion-associated, 5
chr9_-_38021889 0.58 ENSDART00000183482
ENSDART00000124333
adenylate cyclase 5
chr25_-_13839743 0.58 ENSDART00000158780
mitogen-activated protein kinase 8 interacting protein 1a
chr17_-_2386569 0.58 ENSDART00000121614
phospholipase C beta 2
chr3_+_39853788 0.57 ENSDART00000154869
calcium channel, voltage-dependent, T type, alpha 1H subunit a
chr13_+_18371208 0.57 ENSDART00000138172
cell division cycle and apoptosis regulator 1
chr10_-_34870667 0.56 ENSDART00000161272
doublecortin-like kinase 1a
chr1_-_15797663 0.56 ENSDART00000177122
sarcoglycan zeta
chr24_+_24461341 0.56 ENSDART00000147658
basic helix-loop-helix family, member e22
chr10_-_34871737 0.56 ENSDART00000138755
doublecortin-like kinase 1a
chr22_+_34784075 0.56 ENSDART00000167538
ligand dependent nuclear receptor corepressor
chr23_-_37113215 0.55 ENSDART00000146835
zgc:193690
chr3_-_30061985 0.55 ENSDART00000189583
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr17_+_11675362 0.55 ENSDART00000157911
kinesin family member 26Ba
chr25_-_25058508 0.55 ENSDART00000087570
ENSDART00000178891

chr5_+_19712011 0.54 ENSDART00000131924
family with sequence similarity 222, member A
chr5_-_34185115 0.54 ENSDART00000192771
fibrinogen C domain containing 1
chr21_-_5799122 0.54 ENSDART00000129351
ENSDART00000151202
cyclin I
chr6_-_59271270 0.53 ENSDART00000126870
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2b

Network of associatons between targets according to the STRING database.

First level regulatory network of lhx3+lhx4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.5 1.4 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.4 4.8 GO:0006032 chitin catabolic process(GO:0006032)
0.3 1.0 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.3 2.0 GO:0006572 tyrosine catabolic process(GO:0006572)
0.3 1.2 GO:0099563 modification of synaptic structure(GO:0099563)
0.3 1.2 GO:0015677 copper ion import(GO:0015677)
0.3 0.8 GO:0035971 peptidyl-histidine dephosphorylation(GO:0035971)
0.3 0.8 GO:0010265 SCF complex assembly(GO:0010265)
0.2 0.7 GO:0061182 negative regulation of chondrocyte differentiation(GO:0032331) negative regulation of cartilage development(GO:0061037) negative regulation of chondrocyte development(GO:0061182) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158) negative regulation of bone development(GO:1903011)
0.2 0.9 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.2 1.1 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.2 1.1 GO:0002159 desmosome assembly(GO:0002159)
0.2 1.5 GO:0070285 pigment cell development(GO:0070285)
0.2 0.6 GO:0021611 facial nerve formation(GO:0021611)
0.2 1.1 GO:0006788 heme oxidation(GO:0006788)
0.2 0.7 GO:0048313 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.2 1.2 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.2 1.3 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.2 0.6 GO:0071926 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.2 0.8 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.2 1.5 GO:0072506 phosphate ion homeostasis(GO:0055062) trivalent inorganic anion homeostasis(GO:0072506)
0.2 7.9 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 2.2 GO:0042026 protein refolding(GO:0042026)
0.1 0.4 GO:0009750 response to fructose(GO:0009750)
0.1 0.7 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 0.5 GO:0051876 pigment granule dispersal(GO:0051876)
0.1 0.6 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 2.0 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 1.7 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 5.8 GO:0030282 bone mineralization(GO:0030282)
0.1 0.9 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.1 1.6 GO:0032264 IMP salvage(GO:0032264)
0.1 1.2 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 0.4 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.1 0.9 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.1 0.8 GO:0043092 amino acid import(GO:0043090) L-amino acid import(GO:0043092)
0.1 0.6 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 1.6 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.1 1.0 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.5 GO:0097272 ammonia homeostasis(GO:0097272)
0.1 0.6 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 0.8 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.1 1.8 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 2.7 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 0.5 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.1 0.4 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.1 1.5 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.8 GO:0048796 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.1 0.5 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.2 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 3.3 GO:0016126 sterol biosynthetic process(GO:0016126)
0.1 2.0 GO:0055064 chloride ion homeostasis(GO:0055064)
0.1 0.3 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.1 0.8 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 0.7 GO:0015813 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.1 0.8 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 1.3 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 0.7 GO:0038203 TORC2 signaling(GO:0038203)
0.1 2.0 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 0.5 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.1 0.7 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 0.4 GO:0032475 otolith formation(GO:0032475)
0.1 0.9 GO:0006825 copper ion transport(GO:0006825)
0.0 0.4 GO:0098700 equilibrioception(GO:0050957) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.8 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.7 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 1.3 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.4 GO:0019430 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 1.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.7 GO:0006415 translational termination(GO:0006415)
0.0 0.6 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.0 0.7 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.3 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.6 GO:0045471 response to ethanol(GO:0045471)
0.0 1.2 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.5 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.2 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 1.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.4 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 0.5 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.2 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.0 0.6 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 2.1 GO:0006414 translational elongation(GO:0006414)
0.0 0.4 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.7 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.2 GO:0070207 protein trimerization(GO:0070206) protein homotrimerization(GO:0070207)
0.0 0.5 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.3 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.6 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 3.9 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.2 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.4 GO:0003181 atrioventricular valve morphogenesis(GO:0003181)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 1.1 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.7 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 1.8 GO:0006165 nucleoside diphosphate phosphorylation(GO:0006165)
0.0 1.1 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.1 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.5 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.3 GO:0042119 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 0.3 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 1.1 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108)
0.0 0.2 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.9 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.8 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.7 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0010692 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.0 0.1 GO:0035138 pectoral fin morphogenesis(GO:0035138)
0.0 0.2 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 1.8 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.6 GO:0034332 adherens junction organization(GO:0034332)
0.0 0.3 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.4 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.1 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.9 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.1 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.1 GO:0099565 regulation of postsynaptic membrane potential(GO:0060078) chemical synaptic transmission, postsynaptic(GO:0099565)
0.0 0.2 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 1.0 GO:0061515 myeloid cell development(GO:0061515)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0060077 inhibitory synapse(GO:0060077)
0.2 7.4 GO:0005861 troponin complex(GO:0005861)
0.1 0.8 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.4 GO:0031673 H zone(GO:0031673)
0.1 1.3 GO:0031045 dense core granule(GO:0031045)
0.1 0.7 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.3 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.1 1.1 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.7 GO:0071914 prominosome(GO:0071914)
0.1 1.1 GO:0030057 desmosome(GO:0030057)
0.0 3.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.6 GO:0000243 commitment complex(GO:0000243)
0.0 0.8 GO:0005903 brush border(GO:0005903)
0.0 0.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.8 GO:0032420 stereocilium(GO:0032420)
0.0 0.7 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.7 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 1.0 GO:0042734 presynaptic membrane(GO:0042734)
0.0 2.1 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.5 GO:0005869 dynactin complex(GO:0005869)
0.0 1.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.7 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.6 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.6 GO:0043204 perikaryon(GO:0043204)
0.0 0.7 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.6 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.6 GO:0016342 catenin complex(GO:0016342)
0.0 0.5 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.5 GO:0005902 microvillus(GO:0005902)
0.0 0.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.7 GO:0032432 actin filament bundle(GO:0032432)
0.0 1.1 GO:0005884 actin filament(GO:0005884)
0.0 0.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 8.4 GO:0043005 neuron projection(GO:0043005)
0.0 0.8 GO:0045211 postsynaptic membrane(GO:0045211)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.4 4.8 GO:0004568 chitinase activity(GO:0004568)
0.3 1.2 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.3 0.9 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.3 0.8 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.3 0.8 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 1.4 GO:0032052 bile acid binding(GO:0032052)
0.2 0.9 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.2 0.6 GO:0030882 lipid antigen binding(GO:0030882)
0.2 2.7 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.2 0.8 GO:0101006 protein histidine phosphatase activity(GO:0101006)
0.2 1.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.2 0.7 GO:0031005 filamin binding(GO:0031005)
0.2 1.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 1.0 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.2 0.5 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087)
0.2 0.6 GO:0016521 pituitary adenylate cyclase activating polypeptide activity(GO:0016521)
0.1 1.0 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.1 2.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 1.6 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 1.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.5 GO:0072571 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.1 0.8 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 0.5 GO:0004135 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.1 0.4 GO:0019777 Atg12 transferase activity(GO:0019777)
0.1 0.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.6 GO:0016531 copper chaperone activity(GO:0016531)
0.1 1.8 GO:0005504 fatty acid binding(GO:0005504)
0.1 1.9 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.9 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.6 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.4 GO:0019960 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 1.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.3 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.1 0.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 1.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.7 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.9 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.7 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 3.1 GO:0043022 ribosome binding(GO:0043022)
0.1 0.6 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 1.0 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.1 1.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 2.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.2 GO:0001635 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.1 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.0 1.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 1.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.7 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.8 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.6 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 1.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 1.0 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.9 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.0 0.8 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.4 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.3 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.6 GO:0070122 isopeptidase activity(GO:0070122)
0.0 0.4 GO:0030507 spectrin binding(GO:0030507)
0.0 1.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.5 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 2.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.8 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 1.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.5 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.6 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.7 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.5 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.4 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 2.0 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 2.4 GO:0042393 histone binding(GO:0042393)
0.0 1.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.6 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.7 GO:0046332 SMAD binding(GO:0046332)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 0.6 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.2 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.4 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 2.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.2 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.3 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.7 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 2.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 1.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.0 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 0.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 0.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.4 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)