Project

PRJEB1986: zebrafish developmental stages transcriptome

Navigation
Downloads

Results for irf4a+irf4b

Z-value: 0.67

Motif logo

logo of

Transcription factors associated with irf4a+irf4b

Gene Symbol Gene ID Gene Info
irf4a
ENSDARG00000006560 interferon regulatory factor 4a
irf4b
ENSDARG00000055374 interferon regulatory factor 4b
irf4b
ENSDARG00000115381 interferon regulatory factor 4b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
irf4bdr11_v1_chr20_+_26556372_26556372-0.331.7e-01Click!
irf4adr11_v1_chr2_-_879800_8798000.039.1e-01Click!

Activity profile of irf4a+irf4b motif

Sorted Z-values of irf4a+irf4b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_68562464 0.88 ENSDART00000192954
BX548011.4

chr16_+_46497149 0.83 ENSDART00000135151
ENSDART00000058324
rpz4
rapunzel 4
chr9_-_23765480 0.80 ENSDART00000027212
si:ch211-219a4.6
si:ch211-219a4.6
chr9_+_23765587 0.78 ENSDART00000145120
si:ch211-219a4.3
si:ch211-219a4.3
chr15_-_29556757 0.75 ENSDART00000060049
hspa13
heat shock protein 70 family, member 13
chr6_+_15762647 0.73 ENSDART00000127133
ENSDART00000128939
iqca1
IQ motif containing with AAA domain 1
chr25_+_16646113 0.73 ENSDART00000110426
cecr2
cat eye syndrome chromosome region, candidate 2
chr18_-_24988645 0.71 ENSDART00000136434
ENSDART00000085735
chd2
chromodomain helicase DNA binding protein 2
chr12_+_35650321 0.70 ENSDART00000190446
BX255898.1

chr20_-_3911546 0.68 ENSDART00000169787
cnksr3
cnksr family member 3
chr15_+_31911989 0.67 ENSDART00000111472
brca2
breast cancer 2, early onset
chr15_+_2421729 0.66 ENSDART00000082294
ENSDART00000156428
hephl1a
hephaestin-like 1a
chr1_+_31674297 0.65 ENSDART00000044214
wbp1lb
WW domain binding protein 1-like b
chr2_-_59157790 0.59 ENSDART00000192303
ENSDART00000159362
ftr32
finTRIM family, member 32
chr23_-_35396845 0.58 ENSDART00000142038
ENSDART00000049373
ENSDART00000181978
ENSDART00000171357
cmtr1
cap methyltransferase 1
chr4_-_12795436 0.57 ENSDART00000131026
ENSDART00000075127
b2m
beta-2-microglobulin
chr15_+_2421432 0.57 ENSDART00000193772
hephl1a
hephaestin-like 1a
chr20_-_51547464 0.51 ENSDART00000099486
disp1
dispatched homolog 1 (Drosophila)
chr18_-_23874929 0.49 ENSDART00000134910
nr2f2
nuclear receptor subfamily 2, group F, member 2
chr25_+_28862660 0.48 ENSDART00000154681
si:ch211-106e7.2
si:ch211-106e7.2
chr5_-_13766651 0.46 ENSDART00000134064
mxd1
MAX dimerization protein 1
chr13_+_24263049 0.45 ENSDART00000135992
ENSDART00000088005
abcb10
ATP-binding cassette, sub-family B (MDR/TAP), member 10
chr8_-_27687095 0.45 ENSDART00000086946
mov10b.1
Moloney leukemia virus 10b, tandem duplicate 1
chr4_-_12795030 0.45 ENSDART00000150427
b2m
beta-2-microglobulin
chr15_-_40175894 0.43 ENSDART00000156632
si:ch211-281l24.3
si:ch211-281l24.3
chr23_-_30045661 0.42 ENSDART00000122239
ENSDART00000103480
ccdc187
coiled-coil domain containing 187
chr14_-_25309058 0.42 ENSDART00000159569
htr4
5-hydroxytryptamine receptor 4
chr19_+_43669122 0.41 ENSDART00000139151
si:ch211-193k19.1
si:ch211-193k19.1
chr4_-_17669881 0.41 ENSDART00000066997
dram1
DNA-damage regulated autophagy modulator 1
chr15_-_17071328 0.39 ENSDART00000122617
si:ch211-24o10.6
si:ch211-24o10.6
chr16_+_27383717 0.38 ENSDART00000132329
ENSDART00000136256
stx17
syntaxin 17
chr1_-_1885516 0.37 ENSDART00000122187
ENSDART00000131675
si:ch211-132g1.3
si:ch211-132g1.3
chr1_-_35924495 0.36 ENSDART00000184424
smad1
SMAD family member 1
chr17_+_40879331 0.36 ENSDART00000046003
slc4a1ap
solute carrier family 4 (anion exchanger), member 1, adaptor protein
chr7_+_19615056 0.36 ENSDART00000124752
ENSDART00000190297
si:ch211-212k18.15
si:ch211-212k18.15
chr5_+_28260158 0.36 ENSDART00000181434
ncaph
non-SMC condensin I complex, subunit H
chr21_+_45626136 0.36 ENSDART00000158742
irf1b
interferon regulatory factor 1b
chr2_-_43739740 0.35 ENSDART00000113849
kif5ba
kinesin family member 5B, a
chr1_-_7570181 0.35 ENSDART00000103588
mxa
myxovirus (influenza) resistance A
chr8_+_38564942 0.34 ENSDART00000085371
rfk
riboflavin kinase
chr25_+_36045072 0.33 ENSDART00000126326
rpgrip1l
RPGRIP1-like
chr3_-_49554912 0.32 ENSDART00000159392
CR847534.1

chr10_+_7703251 0.32 ENSDART00000165134
ggcx
gamma-glutamyl carboxylase
chr2_+_15586632 0.32 ENSDART00000164903
BX510342.1

chr7_+_42461850 0.32 ENSDART00000190350
adamts18
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr18_-_23875219 0.32 ENSDART00000059976
nr2f2
nuclear receptor subfamily 2, group F, member 2
chr23_-_12906228 0.32 ENSDART00000138807
ndnl2
necdin-like 2
chr3_+_15773991 0.30 ENSDART00000089923
znf652
zinc finger protein 652
chr12_-_35936329 0.30 ENSDART00000166634
rnf213b
ring finger protein 213b
chr24_-_26885897 0.29 ENSDART00000180512
fndc3bb
fibronectin type III domain containing 3Bb
chr19_-_7110617 0.29 ENSDART00000104838
psmb8a
proteasome subunit beta 8A
chr1_+_38153944 0.29 ENSDART00000135666
galnt7
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr13_+_17694845 0.28 ENSDART00000079778
ifit8
interferon-induced protein with tetratricopeptide repeats 8
chr24_-_11467549 0.28 ENSDART00000082264
pxdc1b
PX domain containing 1b
chr13_+_22476742 0.28 ENSDART00000078759
ENSDART00000130101
ENSDART00000137220
ENSDART00000133065
ENSDART00000147348
ldb3a
LIM domain binding 3a
chr6_+_41554794 0.27 ENSDART00000165424
srgap3
SLIT-ROBO Rho GTPase activating protein 3
chr23_-_29553430 0.27 ENSDART00000157773
ENSDART00000126384
ube4b
ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)
chr5_+_59397739 0.26 ENSDART00000148659
clip2
CAP-GLY domain containing linker protein 2
chr6_-_18560190 0.25 ENSDART00000168636
tefm
transcription elongation factor, mitochondrial
chr17_-_22552678 0.25 ENSDART00000079401
si:ch211-125o16.4
si:ch211-125o16.4
chr2_+_2818645 0.25 ENSDART00000163587
rock1
Rho-associated, coiled-coil containing protein kinase 1
chr6_-_10728057 0.25 ENSDART00000002247
sp3b
Sp3b transcription factor
chr19_-_791016 0.24 ENSDART00000037515
msto1
misato 1, mitochondrial distribution and morphology regulator
chr6_-_18400548 0.24 ENSDART00000179797
ENSDART00000164891
trim25
tripartite motif containing 25
chr20_-_6476705 0.23 ENSDART00000077095
trappc8
trafficking protein particle complex 8
chr11_-_30508843 0.23 ENSDART00000101667
ENSDART00000179930
map4k3a
mitogen-activated protein kinase kinase kinase kinase 3a
chr15_-_42760110 0.23 ENSDART00000152490
si:ch211-181d7.3
si:ch211-181d7.3
chr19_+_791538 0.22 ENSDART00000146554
ENSDART00000138406
tmem79a
transmembrane protein 79a
chr1_-_36771712 0.22 ENSDART00000148386
prmt9
protein arginine methyltransferase 9
chr12_+_36109507 0.22 ENSDART00000175409
map2k6
mitogen-activated protein kinase kinase 6
chr22_-_10605045 0.22 ENSDART00000184812
bap1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr18_-_25905574 0.22 ENSDART00000143899
ENSDART00000163369
sema4ba
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Ba
chr3_-_4501026 0.20 ENSDART00000163052
zgc:162198
zgc:162198
chr15_-_1835189 0.20 ENSDART00000154369
taf15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr16_+_35661331 0.19 ENSDART00000161725
map7d1a
MAP7 domain containing 1a
chr8_-_51340773 0.19 ENSDART00000060633
kansl3
KAT8 regulatory NSL complex subunit 3
chr21_+_17301790 0.19 ENSDART00000145057
tsc1b
TSC complex subunit 1b
chr8_-_51340931 0.19 ENSDART00000178209
kansl3
KAT8 regulatory NSL complex subunit 3
chr19_+_10832092 0.19 ENSDART00000191851
tomm40l
translocase of outer mitochondrial membrane 40 homolog, like
chr14_-_25309360 0.18 ENSDART00000088940
htr4
5-hydroxytryptamine receptor 4
chr22_-_8692305 0.17 ENSDART00000181602
CR450686.4

chr23_-_29553691 0.17 ENSDART00000053804
ube4b
ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)
chr12_+_36109071 0.17 ENSDART00000171268
map2k6
mitogen-activated protein kinase kinase 6
chr7_-_26579465 0.17 ENSDART00000173820
si:dkey-62k3.6
si:dkey-62k3.6
chr3_+_36127287 0.17 ENSDART00000058605
ENSDART00000182500
scpep1
serine carboxypeptidase 1
chr4_-_18434924 0.16 ENSDART00000190271
socs2
suppressor of cytokine signaling 2
chr15_-_41734639 0.16 ENSDART00000154230
ENSDART00000167443
ftr90
finTRIM family, member 90
chr8_-_18229169 0.16 ENSDART00000131764
ENSDART00000143036
ENSDART00000145986
si:ch211-241d21.5
si:ch211-241d21.5
chr7_-_19614916 0.15 ENSDART00000169029
zgc:194655
zgc:194655
chr20_-_35012093 0.15 ENSDART00000062761
cnstb
consortin, connexin sorting protein b
chr5_+_65157576 0.15 ENSDART00000159599
cfap157
cilia and flagella associated protein 157
chr7_+_19482877 0.15 ENSDART00000077868
si:ch211-212k18.7
si:ch211-212k18.7
chr22_+_25236657 0.15 ENSDART00000138012
zgc:172218
zgc:172218
chr9_+_23003208 0.14 ENSDART00000021060
eaf2
ELL associated factor 2
chr15_-_43995028 0.14 ENSDART00000172485
ENSDART00000186320
nlrc3l
NLR family, CARD domain containing 3-like
chr6_+_34511886 0.14 ENSDART00000179450
lrp8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr16_-_41667101 0.13 ENSDART00000084528
atp2c1
ATPase secretory pathway Ca2+ transporting 1
chr4_-_26107841 0.13 ENSDART00000172012
si:ch211-244b2.4
si:ch211-244b2.4
chr9_-_32837860 0.13 ENSDART00000142227
mxe
myxovirus (influenza virus) resistance E
chr17_+_35362851 0.12 ENSDART00000137659
cmpk2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr21_+_25793970 0.12 ENSDART00000101217
CLDN4 (1 of many)
zgc:136892
chr8_+_47897734 0.12 ENSDART00000140266
mfn2
mitofusin 2
chr5_+_21922534 0.11 ENSDART00000148092
si:ch73-92i20.1
si:ch73-92i20.1
chr20_+_13781779 0.11 ENSDART00000142999
ENSDART00000152471
lpgat1
lysophosphatidylglycerol acyltransferase 1
chr2_-_13333932 0.11 ENSDART00000150238
ENSDART00000168258
si:dkey-185p13.1
vps4b
si:dkey-185p13.1
vacuolar protein sorting 4b homolog B (S. cerevisiae)
chr1_-_7582859 0.11 ENSDART00000110696
mxb
myxovirus (influenza) resistance B
chr7_+_19483277 0.10 ENSDART00000173750
si:ch211-212k18.7
si:ch211-212k18.7
chr3_-_26171668 0.10 ENSDART00000113890
rabep2
rabaptin, RAB GTPase binding effector protein 2
chr5_+_31959954 0.09 ENSDART00000142826
myo1hb
myosin IHb
chr21_-_22543611 0.09 ENSDART00000177084
myo5b
myosin VB
chr17_+_43895158 0.09 ENSDART00000111123
msh4
mutS homolog 4
chr9_-_30576522 0.08 ENSDART00000101085
morc3a
MORC family CW-type zinc finger 3a
chr4_-_8611841 0.08 ENSDART00000067322
fbxl14b
F-box and leucine-rich repeat protein 14b
chr4_+_11464255 0.07 ENSDART00000008584
gdi2
GDP dissociation inhibitor 2
chr12_-_28975705 0.06 ENSDART00000129173
znf646
zinc finger protein 646
chr21_-_37933833 0.06 ENSDART00000184138
ENSDART00000177664
FO704750.1

chr15_+_34069746 0.06 ENSDART00000163513
arl4aa
ADP-ribosylation factor-like 4aa
chr4_+_66668652 0.04 ENSDART00000169500
si:ch211-149o24.4
si:ch211-149o24.4
chr6_-_52235118 0.04 ENSDART00000191243
tomm34
translocase of outer mitochondrial membrane 34
chr2_-_24554416 0.03 ENSDART00000052061
cnn2
calponin 2
chr12_-_23658888 0.03 ENSDART00000088319
map3k8
mitogen-activated protein kinase kinase kinase 8
chr5_+_66063807 0.03 ENSDART00000122405
jak2b
Janus kinase 2b
chr17_+_30448452 0.03 ENSDART00000153939
lpin1
lipin 1
chr7_+_17908235 0.03 ENSDART00000077113
mta2
metastasis associated 1 family, member 2
chr7_-_20464133 0.03 ENSDART00000078192
cnpy4
canopy4
chr25_+_15997957 0.03 ENSDART00000140047
ppfibp2b
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr18_-_23875370 0.02 ENSDART00000130163
nr2f2
nuclear receptor subfamily 2, group F, member 2
chr6_+_11250316 0.02 ENSDART00000137122
atg9a
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr20_+_2227860 0.02 ENSDART00000152321
tmem200a
transmembrane protein 200A
chr10_+_8101729 0.02 ENSDART00000138875
ENSDART00000123447
ENSDART00000185333
pstpip2
proline-serine-threonine phosphatase interacting protein 2
chr9_+_42269059 0.02 ENSDART00000113435
si:dkey-10c21.1
si:dkey-10c21.1
chr6_-_1566581 0.02 ENSDART00000192993
trim107
tripartite motif containing 107
chr22_+_19365220 0.02 ENSDART00000132781
ENSDART00000135672
ENSDART00000153630
si:dkey-21e2.12
si:dkey-21e2.12
chr2_-_37140423 0.02 ENSDART00000144220
tspan37
tetraspanin 37
chr25_-_483808 0.01 ENSDART00000104720
si:ch1073-385f13.3
si:ch1073-385f13.3
chr9_+_34089156 0.01 ENSDART00000000005
ccdc80
coiled-coil domain containing 80
chr17_-_40879108 0.01 ENSDART00000010362
supt7l
SPT7-like STAGA complex gamma subunit
chr20_+_38525567 0.00 ENSDART00000147787
znf512
zinc finger protein 512

Network of associatons between targets according to the STRING database.

First level regulatory network of irf4a+irf4b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0060843 lymphatic endothelial cell fate commitment(GO:0060838) venous endothelial cell differentiation(GO:0060843) venous endothelial cell fate commitment(GO:0060845)
0.1 0.6 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.1 0.3 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.1 0.5 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.3 GO:0003347 epicardial cell to mesenchymal cell transition(GO:0003347) negative regulation of adherens junction organization(GO:1903392)
0.1 0.2 GO:0039535 RIG-I signaling pathway(GO:0039529) regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039531) regulation of RIG-I signaling pathway(GO:0039535)
0.1 1.0 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.1 0.3 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 1.2 GO:0006825 copper ion transport(GO:0006825)
0.1 0.3 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.2 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 0.4 GO:0050688 regulation of defense response to virus(GO:0050688)
0.1 0.4 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.1 0.8 GO:0042026 protein refolding(GO:0042026)
0.0 0.7 GO:0008585 sex determination(GO:0007530) female gonad development(GO:0008585)
0.0 0.3 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.0 0.6 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.4 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.1 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.5 GO:0042694 muscle cell fate specification(GO:0042694)
0.0 0.3 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.3 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.1 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.1 GO:0014005 microglia development(GO:0014005)
0.0 0.4 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.1 GO:0055071 manganese ion homeostasis(GO:0055071)
0.0 0.2 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0003241 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.1 GO:0048662 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.0 0.2 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 0.2 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.7 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.4 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.2 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.2 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.1 0.7 GO:0031010 ISWI-type complex(GO:0031010)
0.1 0.3 GO:0043034 costamere(GO:0043034)
0.0 0.4 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.3 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.6 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.4 GO:0044545 NSL complex(GO:0044545)
0.0 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.5 GO:0043186 P granule(GO:0043186)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.1 0.8 GO:0001972 retinoic acid binding(GO:0001972)
0.1 1.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.3 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.1 0.6 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.3 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.2 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.6 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.2 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.7 PID FOXM1 PATHWAY FOXM1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 0.6 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.7 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation